MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hand-Arm Vibration Syndrome

(UMLS:C1363854)

Definition:: An occupational disorder resulting from prolonged exposure to vibration, affecting the fingers, hands, and forearms. It occurs in workers who regularly use vibrating tools such as jackhammers, power chain saws, riveters, etc. Symptoms include episodic finger blanching, NUMBNESS, tingling, and loss of nerve sensitivity.
UMLS ID:: C1363854
MeSH ID:: D053421

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.829.380

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.440

Classification 3:

Name:

Occupational Diseases
MeSH Tree Number(s):: C24.400

Synonym(s)

Hand-Arm Vibration Syndrome

Hand and arm vibration syndrome

Hand-arm vibration syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Albuterol	FAERS: 1		US FAERS
2	Moxifloxacin	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Thoracic Outlet Syndrome	31.9%
2	Brachial Plexus Neuritis	29.2%
3	Neuralgic Amyotrophy	29.2%
4	Tarsal Tunnel Syndrome	26.6%
5	Cauda Equina Syndrome	26.6%
6	Causalgia	26.4%
7	Aortic Aneurysm	25.4%
8	Aortitis	25.4%
9	Leriche Syndrome	25.4%
10	Periphlebitis	25.4%
11	Phlebitis	25.4%
12	Thromboangiitis Obliterans	25.4%
13	Neuritis	25%
14	Polyneuritis	25%
15	Radiculitis	25%
16	Polyneuropathy	25%
17	Mononeuritis	25%
18	Mononeuropathies	25%
19	Brachial Plexus Neuropathies	25%
20	Radiculopathy	25%
21	Mononeuropathy Multiplex	25%
22	Nerve Root Compression	25%
23	Thrombophlebitis	24.8%
24	Complex Regional Pain Syndromes	24.3%
25	Myocardial Ischemia	23.2%
26	Postphlebitic Syndrome	23.1%
27	Guillain-Barre Syndrome	22.8%
28	Carotid Artery Thrombosis	22.2%
29	Aortic Rupture	22.2%
30	Retinal Vein Occlusion	22.1%
31	Carpal Tunnel Syndrome	22.1%
32	Sciatica	21.9%
33	Coronary Aneurysm	21.8%
34	Aneurysm	21.8%
35	Angiomatosis	21.8%
36	Aortic Diseases	21.8%
37	Arterial Occlusive Diseases	21.8%
38	Hyperemia	21.8%
39	Hypotension	21.8%
40	Superior Vena Cava Syndrome	21.8%
41	Telangiectasis	21.8%
42	Vasculitis	21.8%
43	Venous Insufficiency	21.8%
44	Peripheral Vascular Diseases	21.8%
45	Embolism and Thrombosis	21.8%
46	Angiodysplasia	21.8%
47	Capillary Leak Syndrome	21.8%
48	Prehypertension	21.8%
49	Moyamoya Disease	21.6%
50	Blue Toe Syndrome	21.4%
51	Malignant Atrophic Papulosis	20.9%
52	Aortic Aneurysm, Abdominal	20.8%
53	Aortic Aneurysm, Thoracic	20.8%
54	Shwartzman Phenomenon	20.8%
55	Intracranial Embolism and Thrombosis	20.7%
56	Myocardial Reperfusion Injury	20.6%
57	Carotid Stenosis	20.3%
58	Intracranial Aneurysm	20.3%
59	Peripheral Nerve Injuries	20.2%
60	Cerebrovascular Disorders	20%
61	Coronary Thrombosis	20%
62	Cerebrovascular Insufficiency	20%
63	Isaacs syndrome	20%
64	Spinal Cord Vascular Diseases	20%
65	Coronary Artery Disease	20%
66	Cubital Tunnel Syndrome	19.9%
67	Diabetic Neuropathies	19.7%
68	Diabetic Amyotrophy	19.7%
69	Diabetic Autonomic Neuropathy	19.7%
70	Neuralgia	19.6%
71	Neuropathic pain	19.6%
72	Vasculitis, Central Nervous System	19.5%
73	Sciatic Neuropathy	18.6%
74	Ulnar Neuropathies	18.6%
75	Lesion of Sciatic Nerve	18.6%
76	Ulnar Neuritis	18.6%
77	Radial nerve compression	18.6%
78	Radial Tunnel Syndrome	18.6%
79	Peroneal Neuropathies	18.6%
80	Radial Neuropathy	18.6%
81	Median Neuropathy	18.6%
82	Sciatic Nerve Palsy	18.6%
83	Femoral Neuropathy	18.6%
84	Tibial Neuropathy	18.6%
85	Ulnar Nerve Palsy	18.6%
86	Radial nerve palsy	18.6%
87	Intracranial Arteriosclerosis	18.5%
88	Cerebral Atherosclerosis	18.5%
89	Cerebral Arteriosclerosis	18.5%
90	Vascular System Injuries	17.9%
91	Acrodynia	17.8%
92	Cerebral Thrombosis	17.6%
93	Intracranial Embolism	17.6%
94	Intracranial Thrombosis	17.6%
95	Reflex Sympathetic Dystrophy	17.5%
96	Compartment syndromes	17.4%
97	Hepatic Veno-Occlusive Disease	17.4%
98	Peliosis Hepatis	17.4%
99	Varicocele	17.4%
100	Motor Neuron Disease	17.4%
101	Giant Cell Arteritis	17.3%
102	Temporal Arteritis	17.3%
103	Arteriovenous fistula	17.3%
104	Polyarteritis Nodosa	17.2%
105	Takayasu Arteritis	17.2%
106	Diabetic Angiopathies	17.1%
107	Reperfusion Injury	17.1%
108	Splenic Infarction	17.1%
109	Vascular Neoplasms	17.1%
110	Vasoplegia	17.1%
111	Hemorrhoids	17%
112	Brain Infarction	16.9%
113	Coronary heart disease	16.9%
114	Myocardial Infarction	16.9%
115	Acute Coronary Syndrome	16.9%
116	Infarction, Middle Cerebral Artery	16.7%
117	Infarction, Anterior Cerebral Artery	16.7%
118	Infarction, Posterior Cerebral Artery	16.7%
119	Optic Neuropathy, Ischemic	16.7%
120	Anterior Ischemic Optic Neuropathy	16.7%
121	Polyradiculoneuropathy	16.6%
122	Polyradiculoneuritis	16.6%
123	Subarachnoid Hemorrhage, Traumatic	16.4%
124	Carotid Artery, Internal, Dissection	16.4%
125	Neuromuscular Junction Diseases	16.4%
126	Sinus Thrombosis, Intracranial	16.1%
127	Aneurysm, Dissecting	16.1%
128	Arteriosclerosis	16.1%
129	Arteritis	16.1%
130	Embolism	16.1%
131	Erythromelalgia	16.1%
132	Fibromuscular Dysplasia	16.1%
133	Malignant Hypertension	16.1%
134	Raynaud Disease	16.1%
135	Thromboembolism	16.1%
136	Thrombosis	16.1%
137	Essential Hypertension	16.1%
138	Aneurysm, Ruptured	16.1%
139	Iliac Aneurysm	16.1%
140	Pulmonary artery stenosis	16.1%
141	White Coat Hypertension	16.1%
142	Systemic Vasculitis	16.1%
143	Embolus	16.1%
144	Vertebral Artery Dissection	15.5%
145	Polyradiculopathy	15.4%
146	Cavernous Sinus Thrombosis	15.4%
147	Sagittal Sinus Thrombosis	15.4%
148	Miller Fisher Syndrome	15.2%
149	Cerebral Infarction	15.1%
150	Brain Stem Infarctions	15.1%
151	Agricultural Workers' Diseases	15.1%
152	Persian Gulf Syndrome	15.1%
153	Lemierre Syndrome	15%
154	Carotid Artery Diseases	14.7%
155	Brain Ischemia	14.7%
156	Hypotension, Orthostatic	14.7%
157	Cerebrovascular accident	14.7%
158	Vasospasm, Intracranial	14.7%
159	Spinal Cord Ischemia	14.7%
160	Intracranial Arterial Diseases	14.7%
161	Post-Exercise Hypotension	14.7%
162	Carotid Artery Injuries	14.6%
163	Mesenteric vascular insufficiency	14.3%
164	Lateral Medullary Syndrome	14.2%
165	Stiff-Person Syndrome	14.1%
166	Kounis Syndrome	14.1%
167	Sturge-Weber Syndrome	14%
168	Angioedema	14%
169	Colitis, Ischemic	13.9%
170	Coronary Occlusion	13.9%
171	Microvascular Angina	13.9%
172	Coronary Stenosis	13.9%
173	ST segment elevation myocardial infarction	13.9%
174	May-Thurner Syndrome	13.9%
175	Angina Pectoris	13.8%
176	Basal Ganglia Cerebrovascular Disease	13.8%
177	Vascular Headaches	13.5%
178	Embolism, Amniotic Fluid	13.5%
179	Myopathy	13.4%
180	Sleep Disorders, Circadian Rhythm	13.4%
181	Arteriosclerosis Obliterans	13.3%
182	Atherosclerosis	13.3%
183	Air Embolism	13.3%
184	Endarteritis	13.3%
185	Venous Thrombosis	13.3%
186	Deep Vein Thrombosis	13.3%
187	Venous Thromboembolism	13.3%
188	Basal Ganglia Hemorrhage	13.2%
189	Shy-Drager Syndrome	13%
190	Retinal Artery Occlusion	12.9%
191	Retinal Vasculitis	12.9%
192	Hypertensive Retinopathy	12.9%
193	Dementia, Vascular	12.8%
194	Anterior Compartment Syndrome	12.7%
195	Vasculitis, Leukocytoclastic, Cutaneous	12.7%
196	Gastric Antral Vascular Ectasia	12.7%
197	Abdominal Compartment Syndrome	12.7%
198	Varicose Ulcer	12.6%
199	Primary Graft Dysfunction	12.6%
200	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	12.5%
201	Coronary Restenosis	12.4%
202	CREST Syndrome	12.3%
203	Neuritis, Autoimmune, Experimental	12.2%
204	Cerebral Arterial Diseases	12.1%
205	Vertebrobasilar Insufficiency	12.1%
206	Anterior Spinal Artery Syndrome	12.1%
207	Basilar Artery Stenosis	12.1%
208	Vertebral Artery Stenosis	12.1%
209	Intracranial Hemorrhage, Hypertensive	12.1%
210	Transient Cerebral Ischemia	12.1%
211	Putaminal Hemorrhage	12.1%
212	Poliomyelitis	11.8%
213	Leukomalacia, Periventricular	11.8%
214	neurofibroma	11.7%
215	Hypoxia-Ischemia, Brain	11.7%
216	Scimitar Syndrome	11.7%
217	Spinal Muscular Atrophy	11.6%
218	Progressive Muscular Atrophy	11.6%
219	Shock, Cardiogenic	11.5%
220	Chronic Fatigue Syndrome	11.5%
221	Angina, Unstable	11.4%
222	Heart Diseases	11.3%
223	Lupus Vasculitis, Central Nervous System	11.3%
224	Progressive bulbar palsy	11.3%
225	Bulbar palsy	11.3%
226	Subclavian Steal Syndrome	10.8%
227	Intermittent Claudication	10.6%
228	Pulmonary Embolism	10.6%
229	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	10.6%
230	Mesenteric Vascular Occlusion	10.6%
231	Mucocutaneous Lymph Node Syndrome	10.6%
232	Myasthenia Gravis	10.6%
233	Diabetic Retinopathy	10.5%
234	No-Reflow Phenomenon	10.5%
235	Livedo Reticularis	10.5%
236	Renal hypertension	10.4%
237	Renal Artery Obstruction	10.4%
238	Renal Artery Stenosis	10.4%
239	Charcot-Marie-Tooth Disease	10.4%
240	Hemangioma, Cavernous	10.3%
241	Amyotrophic Lateral Sclerosis	10.3%
242	Scurvy	10.3%
243	POEMS Syndrome	10.3%
244	Angina Pectoris, Variant	10.2%
245	Subarachnoid Hemorrhage	10%
246	Cerebral Hemorrhage	10%
247	Ataxia Telangiectasia	9.8%
248	Pituitary Apoplexy	9.8%
249	Pneumoconiosis	9.6%
250	Hepatic Vein Thrombosis	9.5%
251	Budd-Chiari Syndrome	9.5%
252	Dermatitis, Occupational	9.5%
253	Cranial nerve diseases	9.4%
254	Demyelinating Diseases	9.4%
255	Demyelination	9.4%
256	Chronobiology Disorders	9.4%
257	Pulmonary Infarction	9.4%
258	Botulism	9%
259	Pregnancy Complications, Cardiovascular	9%
260	Cardiovascular Abnormalities	9%
261	Cerebral Amyloid Angiopathy	8.9%
262	Ischemic contracture	8.9%
263	Angioedemas, Hereditary	8.9%
264	Tricuspid Atresia	8.9%
265	Arrhythmogenic Right Ventricular Dysplasia	8.9%
266	Cryoglobulinemia	8.8%
267	Diabetic Foot	8.8%
268	Myositis	8.6%
269	Myotonic Disorders	8.6%
270	Myasthenic Syndromes, Congenital	8.6%
271	Hypertension, Renovascular	8.5%
272	Hereditary Angioedema Type III	8.5%
273	Hereditary Angioedema Types I and II	8.5%
274	Multiple System Atrophy	8.5%
275	Aortic Valve Stenosis	8.5%
276	Cardiomyopathy, Dilated	8.5%
277	Pulmonary Valve Stenosis	8.5%
278	Lambert-Eaton Myasthenic Syndrome	8.4%
279	Amyloid Neuropathies, Familial	8.4%
280	Brain Hemorrhage, Traumatic	8.2%
281	Asthma, Occupational	8.1%
282	Granulomatosis with polyangiitis	7.8%
283	Trauma, Nervous System	7.7%
284	Purpura, Hyperglobulinemic	7.6%
285	Neurofibrosarcoma	7.6%
286	MELAS Syndrome	7.6%
287	Nervous System Neoplasms	7.5%
288	Neurologic Manifestations	7.5%
289	Neurotoxicity Syndromes	7.5%
290	Restless Legs Syndrome	7.5%
291	Ocular Motility Disorders	7.4%
292	Cyclophoria	7.4%
293	Hypertrophic Cardiomyopathy	7.3%
294	Hypertrophic obstructive cardiomyopathy	7.3%
295	Cardiac Tamponade	7.3%
296	Endocarditis	7.3%
297	Cardiac Arrest	7.3%
298	Heart failure	7.3%
299	Pericardial effusion	7.3%
300	Pericarditis	7.3%
301	Pneumopericardium	7.3%
302	Cor pulmonale	7.3%
303	Ventricular Outflow Obstruction	7.3%
304	Ventricular Dysfunction	7.3%
305	Cardiomyopathies	7.3%
306	Pleuropericarditis	7.3%
307	Encephalomyelitis	7.1%
308	Fibromyalgia	7.1%
309	Prion Diseases	7.1%
310	Autonomic Dysreflexia	7.1%
311	Medial Tibial Stress Syndrome	7.1%
312	Bacterial Endocarditis	7.1%
313	Mitochondrial Myopathies	7.1%
314	Eosinophilia-Myalgia Syndrome	7%
315	Asbestosis	7%
316	Berylliosis	7%
317	Heart Block	7%
318	Silicosis	7%
319	Tachycardia	7%
320	Tachyarrhythmia	7%
321	Hematoma, Subdural	7%
322	Hematoma, Epidural, Cranial	7%
323	Subacute Combined Degeneration	7%
324	Supravalvular aortic stenosis	6.9%
325	Lown-Ganong-Levine Syndrome	6.9%
326	Myotonic Dystrophy	6.9%
327	Aortic coarctation	6.9%
328	Cor Triatriatum	6.9%
329	Coronary Vessel Anomalies	6.9%
330	Patent ductus arteriosus	6.9%
331	Ebstein Anomaly	6.9%
332	Heart Septal Defects	6.9%
333	Tetralogy of Fallot	6.9%
334	Transposition of Great Vessels	6.9%
335	Hypoplastic Left Heart Syndrome	6.9%
336	Ophthalmoplegic Migraine	6.9%
337	Meningoencephalitis	6.9%
338	Behcet Syndrome	6.9%
339	Alstrom Syndrome	6.8%
340	Waldenstrom Macroglobulinemia	6.8%
341	Multiple Myeloma	6.8%
342	Parkinson Disease	6.7%
343	Myotonia Congenita	6.4%
344	Hematoma, Subdural, Intracranial	6.4%
345	Hematoma, Subdural, Chronic	6.4%
346	Hematoma, Subdural, Acute	6.4%
347	Myasthenia Gravis, Autoimmune, Experimental	6.4%
348	Refsum Disease	6.4%
349	Marchiafava-Bignami Disease	6.4%
350	Rheumatoid Vasculitis	6.4%
351	Sick Sinus Syndrome	6.3%
352	Polymyositis	6.3%
353	Sleep Wake Disorders	6.2%
354	Lewy Body Disease	6.2%
355	Pseudoxanthoma Elasticum	6.2%
356	Spinal Cord Injuries	6.1%
357	Striatonigral Degeneration	6.1%
358	Dural Arteriovenous Fistula	6%
359	Dandy-Walker Syndrome	5.9%
360	Familial Periodic Paralysis	5.9%
361	Farmer's Lung	5.9%
362	Dextrocardia	5.9%
363	Long QT Syndrome	5.9%
364	Pneumocephalus	5.9%
365	Asterixis	5.9%
366	Ballismus	5.9%
367	Cardiac Output, High	5.8%
368	Myocardial Stunning	5.8%
369	Low Cardiac Output Syndrome	5.8%
370	Progressive supranuclear palsy	5.7%
371	Adams-Stokes Syndrome	5.7%
372	Atrioventricular Block	5.7%
373	Bundle-Branch Block	5.7%
374	Cardiomegaly	5.7%
375	Postpericardiotomy Syndrome	5.7%
376	Atrial Premature Complexes	5.7%
377	Sinoatrial Block	5.7%
378	Tachycardia, Paroxysmal	5.7%
379	Supraventricular tachycardia	5.7%
380	Tachycardia, Ventricular	5.7%
381	Wolff-Parkinson-White Syndrome	5.7%
382	Tachycardia, Reciprocating	5.7%
383	Cardiac Hypertrophy	5.7%
384	Aortopulmonary Septal Defect	5.7%
385	Double Outlet Right Ventricle	5.7%
386	Endocardial Cushion Defects	5.7%
387	Myocardial bridging	5.7%
388	Aorticopulmonary Septal Defect	5.7%
389	Leukoencephalitis, Acute Hemorrhagic	5.7%
390	Rheumatic Heart Disease	5.7%
391	Myelitis	5.6%
392	Myelitis, Transverse	5.5%
393	Brain Diseases	5.5%
394	Dysautonomia	5.5%
395	Meningitis	5.5%
396	Movement Disorders	5.5%
397	Pachymeningitis	5.5%
398	Spinal Cord Diseases	5.5%
399	Vagus Nerve Disorder	5.5%
400	Glossopharyngeal Neuralgia	5.5%
401	Abducens Nerve Diseases	5.5%
402	Heavy Metal Poisoning, Nervous System	5.5%
403	Tauopathies	5.5%
404	Trochlear Nerve Diseases	5.5%
405	Epidural Abscess	5.4%
406	Olfactory Nerve Injuries	5.4%
407	Aortic Valve Insufficiency	5.4%
408	Restrictive cardiomyopathy	5.4%
409	Endocardial Fibroelastosis	5.4%
410	Heart Rupture, Post-Infarction	5.4%
411	Mitral Valve Insufficiency	5.4%
412	Mitral Valve Stenosis	5.4%
413	Myocarditis	5.4%
414	Pericarditis, Constrictive	5.4%
415	Pulmonary Valve Insufficiency	5.4%
416	Tricuspid Valve Insufficiency	5.4%
417	Tricuspid Valve Stenosis	5.4%
418	Ventricular Dysfunction, Left	5.4%
419	Right Ventricular Dysfunction	5.4%
420	Endomyocardial Fibrosis	5.4%
421	Carditis	5.4%
422	Heart Failure, Systolic	5.4%
423	Heart Failure, Diastolic	5.4%
424	MPTP Poisoning	5.3%
425	Muscular Dystrophy	5.3%
426	Neuroleptic Malignant Syndrome	5.3%
427	Myelinolysis, Central Pontine	5.3%
428	Orbital Myositis	5.3%
429	Pyomyositis	5.2%
430	Neuromyelitis Optica	5.2%
431	Myalgia	5.1%
432	Opsoclonus-Myoclonus Syndrome	5.1%
433	Encephalomyelitis, Acute Disseminated	5.1%
434	Mitochondrial Encephalomyopathies	5.1%
435	Tachycardia, Atrioventricular Nodal Reentry	5.1%
436	Tachycardia, Ectopic Atrial	5.1%
437	Tachycardia, Ectopic Junctional	5.1%
438	Sinus Tachycardia	5.1%
439	Torsades de Pointes	5.1%
440	Accelerated Idioventricular Rhythm	5.1%
441	Truncus Arteriosus, Persistent	5.1%
442	Dyskinesia, Drug-Induced	5%
443	Central Nervous System Cysts	5%
444	Dystonia Musculorum Deformans	4.9%
445	Subdural Effusion	4.9%
446	Parkinsonian Disorders	4.9%
447	Nocturnal Myoclonus Syndrome	4.9%
448	Romano-Ward Syndrome	4.8%
449	Kearns-Sayre syndrome	4.7%
450	Facial Nerve Injuries	4.7%
451	Subacute Bacterial Endocarditis	4.7%
452	Brain Injuries	4.7%
453	Brain Neoplasms	4.6%
454	Multiple Sclerosis	4.6%
455	Spinal Cord Neoplasms	4.6%
456	Leukoencephalopathy, Progressive Multifocal	4.6%
457	Noonan Syndrome	4.6%
458	Central Nervous System Infection	4.5%
459	Optic Neuropathy	4.5%
460	Horner Syndrome	4.4%
461	Aortic Valve Prolapse	4.4%
462	Tricuspid Valve Prolapse	4.4%
463	Takotsubo Cardiomyopathy	4.4%
464	Epilepsy, Post-Traumatic	4.4%
465	Hypokalemic periodic paralysis	4.4%
466	Akathisia, Drug-Induced	4.4%
467	Facial Nerve Diseases	4.3%
468	Craniocerebral Trauma	4.3%
469	Parasomnia	4.3%
470	Dyssomnias	4.3%
471	Welander Distal Myopathy	4.3%
472	Vestibulocochlear Nerve Diseases	4.3%
473	Decerebrate State	4.3%
474	Hemiparesis	4.3%
475	Hydranencephaly	4.3%
476	Meningism	4.3%
477	Neural Tube Defects	4.3%
478	Paresis	4.3%
479	Seizures	4.3%
480	Sensation Disorders	4.3%
481	Tethered Cord Syndrome	4.3%
482	Central Nervous System Neoplasms	4.3%
483	Complex partial seizures	4.3%
484	Iniencephaly	4.3%
485	Craniorachischisis	4.3%
486	Exencephaly	4.3%
487	Monoparesis	4.3%
488	Septo-Optic Dysplasia	4.3%
489	Cortical Dysplasia	4.3%
490	Neurogenic Inflammation	4.3%
491	Gait Disorders, Neurologic	4.3%
492	Neuromuscular Manifestations	4.3%
493	Malformations of Cortical Development	4.3%
494	Fabry Disease	4.3%
495	Sweating, Gustatory	4.3%
496	Auriculotemporal Syndrome	4.3%
497	Limbic Encephalitis	4.3%
498	Huntington Disease	4.2%
499	Sinus Arrhythmia	4.2%
500	Atrial Fibrillation	4.2%
501	Atrial Flutter	4.2%
502	Edema, Cardiac	4.2%
503	Ventricular Fibrillation	4.2%
504	Ventricular Flutter	4.2%
505	Parasystole	4.2%
506	Paroxysmal atrial fibrillation	4.2%
507	Bradycardia	4.2%
508	Diabetic Cardiomyopathies	4.2%
509	Cardiomyopathy, Alcoholic	4.2%
510	Ectopia Cordis	4.2%
511	Sudden Cardiac Death	4.2%
512	Left Ventricular Hypertrophy	4.2%
513	Right Ventricular Hypertrophy	4.2%
514	Single umbilical artery	4.2%
515	Chagas Cardiomyopathy	4.2%
516	Meige Syndrome	4.2%
517	Cerebral Ventriculitis	4.2%
518	Marfan Syndrome	4.2%
519	Scrapie	4.1%
520	Central Cord Syndrome	4.1%
521	Presenile dementia	4%
522	Senile dementia	4%
523	Meningitis, Bacterial	4%
524	Meningitis, Fungal	4%
525	Chorea	4%
526	Lafora Disease	4%
527	Unverricht-Lundborg Syndrome	4%
528	Brain Abscess	4%
529	Ophthalmoplegia	4%
530	External Ophthalmoplegia	4%
531	Carcinoid Heart Disease	3.9%
532	Jet Lag Syndrome	3.9%
533	Canavan Disease	3.9%
534	Alexander Disease	3.9%
535	Cerebellar Neoplasms	3.9%
536	Posterior Leukoencephalopathy Syndrome	3.8%
537	Posterior reversible encephalopathy syndrome	3.8%
538	Tuberous Sclerosis	3.8%
539	Dermatomyositis	3.7%
540	Muscular Dystrophy, Duchenne	3.7%
541	Williams Syndrome	3.7%
542	Pupil Disorders	3.7%
543	Neurobehavioral Manifestations	3.7%
544	Brain Death	3.6%
545	Coma, Post-Head Injury	3.6%
546	Friedreich Ataxia	3.6%
547	Akinetic Mutism	3.6%
548	Anoxic Encephalopathy	3.6%
549	Arachnoiditis	3.6%
550	Basal Ganglia Diseases	3.6%
551	Brain Damage, Chronic	3.6%
552	Cerebellar Diseases	3.6%
553	Encephalitis	3.6%
554	Encephalomalacia	3.6%
555	Epilepsy	3.6%
556	Hydrocephalus	3.6%
557	Congenital Hydrocephalus	3.6%
558	Hypothalamic Diseases	3.6%
559	Aseptic Meningitis	3.6%
560	Syringomyelia	3.6%
561	Thalamic Diseases	3.6%
562	Intracranial Hypertension	3.6%
563	Aura	3.6%
564	Leukoencephalopathy	3.6%
565	Essential Tremor	3.6%
566	Neuroaxonal Dystrophies	3.6%
567	Familial Tremor	3.6%
568	Headache Disorders	3.6%
569	Intracranial Hypotension	3.6%
570	Paraneoplastic Encephalomyelitis	3.6%
571	Brain Edema	3.6%
572	Brain Hypoxia	3.6%
573	Aqueductal Stenosis	3.6%
574	Pneumorrhachis	3.6%
575	Writer's Cramp	3.6%
576	Uveomeningoencephalitic Syndrome	3.5%
577	Vertigo	3.5%
578	Alcohol-Induced Disorders, Nervous System	3.5%
579	Vocal Cord Paralysis	3.5%
580	Sinus Arrest, Cardiac	3.5%
581	Dyspnea, Paroxysmal	3.5%
582	Amblyopia	3.5%
583	Myoclonic Epilepsy	3.4%
584	Epilepsy, Temporal Lobe	3.4%
585	Creutzfeldt-Jakob disease	3.4%
586	Epilepsy, Rolandic	3.4%
587	Benign Rolandic Epilepsy	3.4%
588	Paraneoplastic Cerebellar Degeneration	3.4%
589	Brain Injuries, Diffuse	3.4%
590	Traumatic Brain Injury	3.4%
591	Cerebellar Ataxia	3.4%
592	Supratentorial Neoplasms	3.4%
593	Torticollis	3.4%
594	Multiple Sclerosis, Chronic Progressive	3.4%
595	Multiple Sclerosis, Relapsing-Remitting	3.4%
596	Cerebrospinal Fluid Otorrhea	3.4%
597	Cerebrospinal Fluid Rhinorrhea	3.4%
598	Gait Ataxia	3.4%
599	Tuberculosis, Meningeal	3.3%
600	Hepatolenticular Degeneration	3.2%
601	Tardive Dyskinesia	3.1%
602	Persistent Vegetative State	3.1%
603	Juvenile Myoclonic Epilepsy	3.1%
604	Myoclonic Epilepsies, Progressive	3.1%
605	Alice in Wonderland Syndrome	3.1%
606	Voice Disorders	3.1%
607	Voice Disturbance	3.1%
608	Alcohol Withdrawal Seizures	3%
609	Smith-Magenis syndrome	3%
610	Brain Concussion	3%
611	Akathisia	3%
612	Restlessness	3%
613	Psychomotor Agitation	3%
614	Optic Nerve Glioma	2.9%
615	Pituitary Adenoma	2.9%
616	Pituitary Neoplasms	2.9%
617	Brain Diseases, Metabolic	2.9%
618	Optic Atrophy	2.9%
619	Optic Neuritis	2.9%
620	Papilledema	2.9%
621	Strabismus	2.9%
622	Tolosa-Hunt Syndrome	2.9%
623	Arsenic Poisoning	2.9%
624	Dementia	2.9%
625	Central Nervous System Fungal Infections	2.9%
626	Conus Medullaris Syndrome	2.9%
627	Toxoplasmosis, Cerebral	2.9%
628	Diffuse Axonal Injury	2.8%
629	Brain Stem Neoplasms	2.8%
630	Facial Injuries	2.8%
631	Facial Neuralgia	2.8%
632	Sleep Talking	2.8%
633	Manganese Poisoning	2.8%
634	Sleep Disorders, Intrinsic	2.8%
635	Orthostatic intolerance	2.8%
636	Anosmia	2.8%
637	Ataxia	2.8%
638	Athetosis	2.8%
639	Catalepsy	2.8%
640	Dystonia	2.8%
641	Hemiplegia	2.8%
642	Locked-In Syndrome	2.8%
643	Meningeal Neoplasms	2.8%
644	Meningomyelocele	2.8%
645	Muscle Hypertonia	2.8%
646	Muscle hypotonia	2.8%
647	Myoclonus	2.8%
648	Myotonia	2.8%
649	Paraplegia	2.8%
650	Pseudobulbar Palsy	2.8%
651	Quadriplegia	2.8%
652	Spasm	2.8%
653	Spastic Paraplegia	2.8%
654	Status Epilepticus	2.8%
655	Taste Disorders	2.8%
656	Tremor	2.8%
657	Spina Bifida	2.8%
658	Monoplegia	2.8%
659	Hypokinesia	2.8%
660	Paraparesis	2.8%
661	Bradykinesia	2.8%
662	Waxy flexibility	2.8%
663	Action Tremor	2.8%
664	Resting Tremor	2.8%
665	Dysosmia	2.8%
666	Quadriparesis	2.8%
667	Mercury Poisoning, Nervous System	2.8%
668	Olfaction Disorders	2.8%
669	Myokymia	2.8%
670	Lead Poisoning, Nervous System	2.8%
671	Vestibular Neuronitis	2.8%
672	Somatosensory Disorders	2.8%
673	Hyperkinesia	2.8%
674	Intention tremor	2.8%
675	Amnesia, Transient Global	2.8%
676	Gait Apraxia	2.7%
677	Meningitis, Cryptococcal	2.7%
678	Meningitis, Listeria	2.7%
679	Meningitis, Haemophilus	2.7%
680	Meningitis, Pneumococcal	2.7%
681	Frontotemporal dementia	2.7%
682	Cerebral Palsy	2.7%
683	Epilepsies, Partial	2.7%
684	Epilepsy, Generalized	2.7%
685	Pseudotumor Cerebri	2.7%
686	Hypertensive Encephalopathy	2.7%
687	Simple Partial Seizures	2.7%
688	Epilepsy, Reflex	2.7%
689	Postural Orthostatic Tachycardia Syndrome	2.7%
690	Headache Disorders, Primary	2.7%
691	Headache Disorders, Secondary	2.7%
692	Medication overuse headache	2.7%
693	Reflex, Abnormal	2.6%
694	Hyporeflexia	2.6%
695	Hyperreflexia	2.6%
696	Choroid Plexus Papilloma	2.5%
697	Turner Syndrome	2.5%
698	Subacute Sclerosing Panencephalitis	2.5%
699	Brain Contusion	2.4%
700	Vision Disorders	2.4%
701	Metamorphopsia	2.4%
702	Visual Impairment	2.4%
703	Central Nervous System Bacterial Infections	2.4%
704	Adrenoleukodystrophy	2.4%
705	Facial Hemiatrophy	2.4%
706	Melkersson-Rosenthal Syndrome	2.4%
707	Anisocoria	2.3%
708	Confusion	2.3%
709	Facial paralysis	2.3%
710	Lethargy	2.3%
711	Memory Disorders	2.3%
712	Muscle Cramp	2.3%
713	Perceptual Disorders	2.3%
714	Psychomotor Disorders	2.3%
715	Tonic Pupil	2.3%
716	Anhedonia	2.3%
717	Disorientation	2.3%
718	Facial Paresis	2.3%
719	Memory Loss	2.3%
720	Hemisensory Neglect	2.3%
721	Dysacusis	2.3%
722	Sleep Bruxism	2.3%
723	Anencephaly	2.3%
724	Meningocele	2.3%
725	Muscular Atrophy	2.3%
726	Respiratory Paralysis	2.3%
727	Encephalocele	2.3%
728	Classical Lissencephalies and Subcortical Band Heterotopias	2.3%
729	Tetany	2.3%
730	Kartagener Syndrome	2.3%
731	Auditory Perceptual Disorders	2.3%
732	Acoustic Neuroma	2.2%
733	Post-Traumatic Headache	2.2%
734	Tension Headache	2.2%
735	Epilepsy, Complex Partial	2.2%
736	Migraine Disorders	2.2%
737	Abdominal Migraine	2.2%
738	Status Migrainosus	2.2%
739	Cervicogenic Headache	2.2%
740	Pituitary Diseases	2.2%
741	Esotropia	2.1%
742	Exotropia	2.1%
743	Sleep Apnea Syndromes	2.1%
744	Kluver-Bucy Syndrome	2.1%
745	Alexia	2.1%
746	Dyslexia	2.1%
747	Disorders of Excessive Somnolence	2.1%
748	Sleep Initiation and Maintenance Disorders	2.1%
749	Night Terrors	2.1%
750	Somnambulism	2.1%
751	Trigeminal Nerve Disorder	2.1%
752	Transient Insomnia	2.1%
753	Sleep Paralysis	2.1%
754	Chronic Insomnia	2.1%
755	REM Sleep Behavior Disorder	2.1%
756	Hypersomnia	2.1%
757	Dermal Sinus	2.1%
758	Dysgeusia	2.1%
759	Formication	2.1%
760	Hyperalgesia	2.1%
761	Hyperesthesia	2.1%
762	Hypesthesia	2.1%
763	Language Disorders	2.1%
764	Numbness	2.1%
765	Paresthesia	2.1%
766	Paraparesis, Spastic	2.1%
767	Spina Bifida Cystica	2.1%
768	Trismus	2.1%
769	Spina Bifida Occulta	2.1%
770	Epilepsia Partialis Continua	2.1%
771	Hypogeusia	2.1%
772	Meningeal Carcinomatosis	2.1%
773	Brown-Sequard Syndrome	2.1%
774	Lissencephaly	2.1%
775	Polymicrogyria	2.1%
776	Pachygyria	2.1%
777	Schizencephaly	2.1%
778	Lockjaw	2.1%
779	Allodynia	2.1%
780	Lead Poisoning, Nervous System, Childhood	2.1%
781	Lead Poisoning, Nervous System, Adult	2.1%
782	Periventricular Nodular Heterotopia	2.1%
783	Ageusia	2.1%
784	Tuberculosis, Central Nervous System	2.1%
785	Duane Retraction Syndrome	2%
786	West Nile Fever	2%
787	Consciousness Disorders	2%
788	Mental Retardation	2%
789	Muscle Weakness	2%
790	Depressed Level of Consciousness	2%
791	Mental deficiency	2%
792	Intellectual Disability	2%
793	Mobius Syndrome	2%
794	Bell Palsy	2%
795	Catatonia	2%
796	Herpes Zoster Oticus	2%
797	Cluster Headache	2%
798	Migraine with Aura	2%
799	Familial Hemiplegic Migraine	2%
800	Chronic Paroxysmal Hemicrania	2%
801	SUNCT Syndrome	2%
802	Paroxysmal Hemicrania	2%
803	Aphonia	2%
804	Sleep Deprivation	2%
805	Dysphonia	2%
806	Optic Atrophy, Hereditary, Leber	1.8%
807	Eye Injuries	1.8%
808	Empty Sella Syndrome	1.8%
809	Hyperpituitarism	1.8%
810	Hypopituitarism	1.8%
811	Hypophysitis	1.8%
812	Congenital nystagmus	1.8%
813	Diplopia	1.7%
814	Muscle Rigidity	1.7%
815	Muscle Spasticity	1.7%
816	Scotoma	1.7%
817	Photophobia	1.7%
818	Cogwheel Rigidity	1.7%
819	Hemifacial Spasm	1.7%
820	Amaurosis	1.7%
821	Blindness	1.7%
822	Nuchal Rigidity	1.7%
823	Reye Syndrome	1.7%
824	Neuroaspergillosis	1.7%
825	Sleep Apnea, Obstructive	1.7%
826	Sleep Apnea, Central	1.7%
827	Hepatic Encephalopathy	1.7%
828	Narcolepsy	1.7%
829	Trigeminal Neuralgia	1.7%
830	Kleine-Levin Syndrome	1.7%
831	Agraphia	1.7%
832	Anomia	1.7%
833	Cluttering	1.7%
834	Language Development Disorders	1.7%
835	Speech Disorders	1.7%
836	Syncope	1.7%
837	Stupor	1.7%
838	Dysgraphia	1.7%
839	Presyncope	1.7%
840	Dyslalia	1.7%
841	Agnosia	1.7%
842	Apraxias	1.7%
843	Hallucinations	1.7%
844	Hemianopsia	1.7%
845	Hyperacusis	1.7%
846	Tinnitus	1.7%
847	Visual Agnosia	1.7%
848	Anosognosia	1.7%
849	Wernicke-Korsakoff Syndrome	1.7%
850	Phonophobia	1.7%
851	Hearing Loss	1.7%
852	Sarcopenia	1.7%
853	Neuronal Ceroid-Lipofuscinoses	1.7%
854	Hyperprolactinemia	1.6%
855	Pick Disease of the Brain	1.5%
856	Cataplexy	1.5%
857	Aphasia	1.5%
858	Articulation Disorders	1.5%
859	Echolalia	1.5%
860	Stuttering	1.5%
861	Dysphasia	1.5%
862	Aicardi's syndrome	1.5%
863	Pseudorabies	1.5%
864	Hoarseness	1.5%
865	Cockayne Syndrome	1.5%
866	Alcohol Withdrawal Delirium	1.5%
867	Amnesia	1.5%
868	Delirium	1.5%
869	Dissociative Amnesia	1.5%
870	Color blindness	1.5%
871	Global Amnesia	1.5%
872	Cri-du-Chat Syndrome	1.5%
873	Down Syndrome	1.5%
874	Brain Diseases, Metabolic, Inborn	1.5%
875	Trisomy 21	1.5%
876	Meningioma	1.5%
877	Microcephaly	1.5%
878	Macrocephaly	1.5%
879	Dysarthria	1.5%
880	Neurosyphilis	1.5%
881	Toxoplasmosis, Congenital	1.4%
882	Porencephaly	1.4%
883	Eye Burns	1.4%
884	Malaria, Cerebral	1.4%
885	Neurocysticercosis	1.4%
886	Amaurosis Fugax	1.4%
887	Blindness, Cortical	1.4%
888	Dyscalculia	1.4%
889	Rett Syndrome	1.4%
890	Deafness	1.4%
891	Hearing Loss, Sudden	1.4%
892	Gerstmann Syndrome	1.4%
893	Hearing Loss, Bilateral	1.4%
894	Hearing Loss, High-Frequency	1.4%
895	Hearing Loss, Mixed Conductive-Sensorineural	1.4%
896	Prosopagnosia	1.4%
897	Apraxia, Ideomotor	1.4%
898	Charles Bonnet Syndrome	1.4%
899	Hearing Loss, Unilateral	1.4%
900	Complete Hearing Loss	1.4%
901	Alien Hand Syndrome	1.4%
902	Deaf Mutism	1.4%
903	Holoprosencephaly	1.4%
904	Waterhouse-Friderichsen Syndrome	1.3%
905	Mutism	1.3%
906	Selective Mutism	1.3%
907	Acromegaly	1.3%
908	Prader-Willi Syndrome	1.3%
909	Wernicke Encephalopathy	1.3%
910	Menkes Kinky Hair Syndrome	1.3%
911	AIDS Dementia Complex	1.3%
912	Phantom pain	1.3%
913	Phantom Limb Pain	1.3%
914	Lyme Neuroborreliosis	1.3%
915	Corneal Scar	1.2%
916	Retrograde amnesia	1.2%
917	Amnesia, Anterograde	1.2%
918	Alexia, Pure	1.2%
919	Kernicterus	1.1%
920	Corneal Perforation	1.1%
921	Fragile X Syndrome	1.1%
922	Nelson Syndrome	1%
923	Rubinstein-Taybi Syndrome	1%
924	Prolactinoma	1%
925	Growth Hormone-Secreting Pituitary Adenoma	1%
926	Galactosemias	0.9%
927	Urea Cycle Disorders, Inborn	0.9%
928	Tyrosinemias	0.9%
929	Homocystinuria	0.8%
930	Leigh Disease	0.8%
931	Mucopolysaccharidosis II	0.8%
932	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.7%
933	Glycogen storage disease type II	0.7%
934	Zellweger Syndrome	0.6%
935	Gaucher Disease	0.6%
936	Tay-Sachs Disease	0.5%
937	Niemann-Pick Disease, Type C	0.5%

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