MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypertrophic obstructive cardiomyopathy

(UMLS:C4551472)

UMLS ID:: C4551472
MeSH ID:: D002312

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.238.100|C14.280.484.150.070.160

Synonym(s)

Hypertrophic obstructive cardiomyopathy

CARDIOMYOPATHY, HYPERTROPHIC OBSTRUCTIVE

HOCM - Hypertrophic obstructive cardiomyopathy

Hypertrophic cardiomyopathy

Obstructive cardiomyopathy

Obstructive hypertrophic cardiomyopathy

cardiomyopathy; hypertrophic, obstructive

obstructive hypertrophic cardiomyopathy

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Betamethasone	FAERS: 3	US FAERS
2	Celecoxib	FAERS: 1	US FAERS
3	Prednisone	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Cardiomyopathy, Dilated	45.3%
2	Pulmonary Valve Stenosis	40.3%
3	Restrictive cardiomyopathy	38.8%
4	Endocardial Fibroelastosis	38.8%
5	Myocarditis	38.8%
6	Endomyocardial Fibrosis	38.8%
7	Carditis	38.8%
8	Supravalvular aortic stenosis	36.4%
9	Myocardial Ischemia	35.7%
10	Cardiac Tamponade	35.2%
11	Endocarditis	35.2%
12	Cardiac Arrest	35.2%
13	Heart failure	35.2%
14	Pericardial effusion	35.2%
15	Pericarditis	35.2%
16	Pneumopericardium	35.2%
17	Cor pulmonale	35.2%
18	Ventricular Outflow Obstruction	35.2%
19	Ventricular Dysfunction	35.2%
20	Pleuropericarditis	35.2%
21	Arrhythmogenic Right Ventricular Dysplasia	33.7%
22	Aortic Valve Insufficiency	32.2%
23	Mitral Valve Insufficiency	32.2%
24	Mitral Valve Stenosis	32.2%
25	Pulmonary Valve Insufficiency	32.2%
26	Tricuspid Valve Insufficiency	32.2%
27	Tricuspid Valve Stenosis	32.2%
28	Myocardial Reperfusion Injury	32%
29	Tricuspid Atresia	30.4%
30	Diabetic Cardiomyopathies	29.2%
31	Cardiomyopathy, Alcoholic	29%
32	Chagas Cardiomyopathy	28.9%
33	Cardiac Output, High	26.8%
34	Myocardial Stunning	26.8%
35	Low Cardiac Output Syndrome	26.8%
36	Cardiomegaly	26.4%
37	Postpericardiotomy Syndrome	26.4%
38	Cardiac Hypertrophy	26.4%
39	Rheumatic Heart Disease	26%
40	Aortic Valve Stenosis	25.9%
41	Heart Block	25.7%
42	Tachycardia	25.7%
43	Tachyarrhythmia	25.7%
44	Lown-Ganong-Levine Syndrome	21.9%
45	Vascular Diseases	21.6%
46	Coronary heart disease	21.4%
47	Myocardial Infarction	21.4%
48	Acute Coronary Syndrome	21.4%
49	Long QT Syndrome	21.4%
50	Heart Rupture, Post-Infarction	21.3%
51	Pericarditis, Constrictive	21.3%
52	Ventricular Dysfunction, Left	21.3%
53	Right Ventricular Dysfunction	21.3%
54	Heart Failure, Systolic	21.3%
55	Heart Failure, Diastolic	21.3%
56	Aortic Valve Prolapse	21.1%
57	Tricuspid Valve Prolapse	21.1%
58	Sick Sinus Syndrome	18.7%
59	Adams-Stokes Syndrome	17.5%
60	Atrioventricular Block	17.5%
61	Bundle-Branch Block	17.5%
62	Atrial Premature Complexes	17.5%
63	Sinoatrial Block	17.5%
64	Tachycardia, Paroxysmal	17.5%
65	Supraventricular tachycardia	17.5%
66	Tachycardia, Ventricular	17.5%
67	Wolff-Parkinson-White Syndrome	17.5%
68	Tachycardia, Reciprocating	17.5%
69	Kounis Syndrome	17.4%
70	Aortic coarctation	17%
71	Cor Triatriatum	17%
72	Coronary Vessel Anomalies	17%
73	Patent ductus arteriosus	17%
74	Ebstein Anomaly	17%
75	Heart Septal Defects	17%
76	Tetralogy of Fallot	17%
77	Transposition of Great Vessels	17%
78	Hypoplastic Left Heart Syndrome	17%
79	Carcinoid Heart Disease	17%
80	Angina Pectoris	17%
81	Bacterial Endocarditis	16.9%
82	Pregnancy Complications, Cardiovascular	16.3%
83	Cardiovascular Abnormalities	16.3%
84	Sinus Arrhythmia	16%
85	Atrial Fibrillation	16%
86	Atrial Flutter	16%
87	Edema, Cardiac	16%
88	Ventricular Fibrillation	16%
89	Ventricular Flutter	16%
90	Parasystole	16%
91	Paroxysmal atrial fibrillation	16%
92	Bradycardia	16%
93	Coronary Aneurysm	16%
94	Sudden Cardiac Death	15.9%
95	Left Ventricular Hypertrophy	15.9%
96	Right Ventricular Hypertrophy	15.9%
97	Cardiomyopathies	15.1%
98	Takotsubo Cardiomyopathy	14.6%
99	Coronary Occlusion	14.6%
100	Microvascular Angina	14.6%
101	Coronary Stenosis	14.6%
102	ST segment elevation myocardial infarction	14.6%
103	Coronary Thrombosis	14.6%
104	Coronary Artery Disease	14.6%
105	Romano-Ward Syndrome	14.5%
106	Dextrocardia	14.2%
107	Tachycardia, Atrioventricular Nodal Reentry	13.5%
108	Tachycardia, Ectopic Atrial	13.5%
109	Tachycardia, Ectopic Junctional	13.5%
110	Sinus Tachycardia	13.5%
111	Torsades de Pointes	13.5%
112	Accelerated Idioventricular Rhythm	13.5%
113	Dyspnea, Paroxysmal	12.8%
114	Williams Syndrome	12.2%
115	Hypertrophic Cardiomyopathy	12.2%
116	Hypertrophic obstructive cardiomyopathy	12.2%
117	Aneurysm	11.7%
118	Angiomatosis	11.7%
119	Aortic Diseases	11.7%
120	Arterial Occlusive Diseases	11.7%
121	Hyperemia	11.7%
122	Hypotension	11.7%
123	Superior Vena Cava Syndrome	11.7%
124	Telangiectasis	11.7%
125	Vasculitis	11.7%
126	Venous Insufficiency	11.7%
127	Peripheral Vascular Diseases	11.7%
128	Embolism and Thrombosis	11.7%
129	Angiodysplasia	11.7%
130	Capillary Leak Syndrome	11.7%
131	Prehypertension	11.7%
132	Shock, Cardiogenic	11.7%
133	Aortopulmonary Septal Defect	11.6%
134	Double Outlet Right Ventricle	11.6%
135	Endocardial Cushion Defects	11.6%
136	Myocardial bridging	11.6%
137	Aorticopulmonary Septal Defect	11.6%
138	Angina, Unstable	11.6%
139	Coronary Restenosis	11.2%
140	Sinus Arrest, Cardiac	10.9%
141	Noonan Syndrome	10.8%
142	Aortic Aneurysm	10.7%
143	Aortitis	10.7%
144	Leriche Syndrome	10.7%
145	Periphlebitis	10.7%
146	Phlebitis	10.7%
147	Thromboangiitis Obliterans	10.7%
148	Embolism, Amniotic Fluid	10%
149	Marfan Syndrome	9.7%
150	Kearns-Sayre syndrome	9.5%
151	Retinal Vein Occlusion	9.4%
152	Subacute Bacterial Endocarditis	9.3%
153	Vascular System Injuries	9.3%
154	Postphlebitic Syndrome	9%
155	Truncus Arteriosus, Persistent	9%
156	Angina Pectoris, Variant	9%
157	Arteriovenous fistula	8.9%
158	Compartment syndromes	8.9%
159	Hepatic Veno-Occlusive Disease	8.9%
160	Peliosis Hepatis	8.9%
161	Varicocele	8.9%
162	Cerebrovascular Disorders	8.8%
163	Diabetic Angiopathies	8.8%
164	Reperfusion Injury	8.8%
165	Splenic Infarction	8.8%
166	Cerebrovascular Insufficiency	8.8%
167	Vascular Neoplasms	8.8%
168	Spinal Cord Vascular Diseases	8.8%
169	Vasoplegia	8.8%
170	Hemorrhoids	8.7%
171	Thoracic Outlet Syndrome	8.7%
172	Malignant Atrophic Papulosis	8.6%
173	Shwartzman Phenomenon	8.5%
174	May-Thurner Syndrome	8.5%
175	Thrombophlebitis	8.1%
176	Blue Toe Syndrome	7.7%
177	Aortic Rupture	7.4%
178	Hand-Arm Vibration Syndrome	7.3%
179	Aortic Aneurysm, Abdominal	7.3%
180	Aortic Aneurysm, Thoracic	7.3%
181	Scimitar Syndrome	7.2%
182	Intracranial Embolism and Thrombosis	7.2%
183	Carotid Stenosis	7.1%
184	Intracranial Aneurysm	7.1%
185	Optic Neuropathy, Ischemic	7.1%
186	Anterior Ischemic Optic Neuropathy	7.1%
187	Mesenteric vascular insufficiency	7.1%
188	Aneurysm, Dissecting	7.1%
189	Arteriosclerosis	7.1%
190	Arteritis	7.1%
191	Embolism	7.1%
192	Erythromelalgia	7.1%
193	Fibromuscular Dysplasia	7.1%
194	Malignant Hypertension	7.1%
195	Raynaud Disease	7.1%
196	Thromboembolism	7.1%
197	Thrombosis	7.1%
198	Essential Hypertension	7.1%
199	Aneurysm, Ruptured	7.1%
200	Iliac Aneurysm	7.1%
201	Pulmonary artery stenosis	7.1%
202	White Coat Hypertension	7.1%
203	Systemic Vasculitis	7.1%
204	Embolus	7.1%
205	Angioedema	6.9%
206	Colitis, Ischemic	6.9%
207	Carotid Artery Thrombosis	6.7%
208	Moyamoya Disease	6.7%
209	Vasculitis, Central Nervous System	6.2%
210	Polyarteritis Nodosa	5.9%
211	Takayasu Arteritis	5.9%
212	Intracranial Arteriosclerosis	5.8%
213	Cerebral Atherosclerosis	5.8%
214	Cerebral Arteriosclerosis	5.8%
215	Turner Syndrome	5.6%
216	Retinal Artery Occlusion	5.4%
217	Retinal Vasculitis	5.4%
218	Hypertensive Retinopathy	5.4%
219	Anterior Compartment Syndrome	5.3%
220	Vasculitis, Leukocytoclastic, Cutaneous	5.3%
221	Gastric Antral Vascular Ectasia	5.3%
222	Abdominal Compartment Syndrome	5.3%
223	Carotid Artery Diseases	5.3%
224	Brain Ischemia	5.3%
225	Ectopia Cordis	5.3%
226	Hypotension, Orthostatic	5.3%
227	Cerebrovascular accident	5.3%
228	Varicose Ulcer	5.3%
229	Vasospasm, Intracranial	5.3%
230	Spinal Cord Ischemia	5.3%
231	Intracranial Arterial Diseases	5.3%
232	Primary Graft Dysfunction	5.3%
233	Single umbilical artery	5.3%
234	Post-Exercise Hypotension	5.3%
235	Cerebral Thrombosis	5.1%
236	Intracranial Embolism	5.1%
237	Intracranial Thrombosis	5.1%
238	Giant Cell Arteritis	4.9%
239	Temporal Arteritis	4.9%
240	Arteriosclerosis Obliterans	4.9%
241	Atherosclerosis	4.9%
242	Air Embolism	4.9%
243	Endarteritis	4.9%
244	Venous Thrombosis	4.9%
245	Deep Vein Thrombosis	4.9%
246	Venous Thromboembolism	4.9%
247	Brain Infarction	4.8%
248	CREST Syndrome	4.5%
249	Mesenteric Vascular Occlusion	4.3%
250	Mucocutaneous Lymph Node Syndrome	4.3%
251	Diabetic Retinopathy	4.3%
252	Sturge-Weber Syndrome	4.3%
253	Livedo Reticularis	4.3%
254	Kartagener Syndrome	4.3%
255	Renal hypertension	4.3%
256	Renal Artery Obstruction	4.3%
257	Renal Artery Stenosis	4.3%
258	Hemangioma, Cavernous	4.2%
259	Basal Ganglia Cerebrovascular Disease	4.2%
260	Vascular Headaches	4.2%
261	Scurvy	4.2%
262	Vertebral Artery Dissection	4.2%
263	Sinus Thrombosis, Intracranial	4.2%
264	Lemierre Syndrome	4.1%
265	Subarachnoid Hemorrhage, Traumatic	4.1%
266	Carotid Artery, Internal, Dissection	4.1%
267	Infarction, Middle Cerebral Artery	3.8%
268	Infarction, Anterior Cerebral Artery	3.8%
269	Infarction, Posterior Cerebral Artery	3.8%
270	Intermittent Claudication	3.7%
271	Pulmonary Embolism	3.7%
272	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.7%
273	Cerebral Infarction	3.7%
274	Brain Stem Infarctions	3.7%
275	No-Reflow Phenomenon	3.7%
276	Cavernous Sinus Thrombosis	3.7%
277	Sagittal Sinus Thrombosis	3.7%
278	Carotid Artery Injuries	3.7%
279	Cerebral Arterial Diseases	3.6%
280	Vertebrobasilar Insufficiency	3.6%
281	Anterior Spinal Artery Syndrome	3.6%
282	Basilar Artery Stenosis	3.6%
283	Vertebral Artery Stenosis	3.6%
284	Intracranial Hemorrhage, Hypertensive	3.6%
285	Transient Cerebral Ischemia	3.6%
286	Dural Arteriovenous Fistula	3.6%
287	Ischemic contracture	3.6%
288	Angioedemas, Hereditary	3.6%
289	Cryoglobulinemia	3.5%
290	Leukomalacia, Periventricular	3.5%
291	Diabetic Foot	3.5%
292	Basal Ganglia Hemorrhage	3.2%
293	Lateral Medullary Syndrome	3.2%
294	Shy-Drager Syndrome	3%
295	Purpura, Hyperglobulinemic	3%
296	Hypertension, Renovascular	2.9%
297	Subarachnoid Hemorrhage	2.9%
298	Hypoxia-Ischemia, Brain	2.9%
299	Cerebral Hemorrhage	2.9%
300	Hepatic Vein Thrombosis	2.9%
301	Budd-Chiari Syndrome	2.9%
302	Hereditary Angioedema Type III	2.9%
303	Hereditary Angioedema Types I and II	2.9%
304	Pulmonary Infarction	2.8%
305	Subclavian Steal Syndrome	2.8%
306	Behcet Syndrome	2.7%
307	Waldenstrom Macroglobulinemia	2.7%
308	Multiple Myeloma	2.7%
309	Putaminal Hemorrhage	2.6%
310	Dementia, Vascular	2.5%
311	Pituitary Apoplexy	2.5%
312	Ataxia Telangiectasia	2.4%
313	Pseudoxanthoma Elasticum	2.4%
314	Granulomatosis with polyangiitis	2.3%
315	Cerebral Amyloid Angiopathy	2.2%
316	Lupus Vasculitis, Central Nervous System	2.2%
317	Rheumatoid Vasculitis	2.1%
318	Hematoma, Subdural	1.4%
319	Hematoma, Epidural, Cranial	1.4%
320	MELAS Syndrome	1.3%
321	Brain Hemorrhage, Traumatic	1.3%
322	Hematoma, Subdural, Intracranial	1.2%
323	Hematoma, Subdural, Chronic	1.2%
324	Hematoma, Subdural, Acute	1.2%
325	Fabry Disease	1%

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