MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Takotsubo Cardiomyopathy

(UMLS:C1739395)

Definition:: A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.
UMLS ID:: C1739395
MeSH ID:: D054549

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.945.900.500

Synonym(s)

Takotsubo Cardiomyopathy

Broken-heart syndrome

Left ventricular ballooning syndrome

Stress cardiomyopathy

Takotsubo cardiomyopathy

Takotsubo syndrome

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amphetamine	18177388	CTD
2	Cocaine	18180533	CTD
3	Dipyridamole	20340053	CTD
4	Disopyramide	18827420	CTD
5	Dobutamine	View details 19204641 19358948 19716052 19838460 20486954 20505295	CTD
6	Epinephrine	View details 17087335 19204641 19300450 19358948 19584984 19720784 20455042	CTD
7	Fluorouracil	19300240 19305108	CTD
8	Ketamine	19204641	CTD
9	Metoprolol	19300450	CTD
10	Nortriptyline	18568805	CTD
11	Succinylcholine	18829243	CTD
12	lumiracoxib	18092115	CTD
13	zolmitriptan	24100257	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Right Ventricular Dysfunction	34.4%
2	Cardiac Tamponade	25.4%
3	Endocarditis	25.4%
4	Cardiac Arrest	25.4%
5	Heart failure	25.4%
6	Pericardial effusion	25.4%
7	Pericarditis	25.4%
8	Pneumopericardium	25.4%
9	Cor pulmonale	25.4%
10	Ventricular Outflow Obstruction	25.4%
11	Cardiomyopathies	25.4%
12	Pleuropericarditis	25.4%
13	Myocardial Ischemia	23%
14	Aortic Valve Stenosis	19.8%
15	Cardiomyopathy, Dilated	19.8%
16	Pulmonary Valve Stenosis	19.8%
17	Cardiac Output, High	17.2%
18	Myocardial Stunning	17.2%
19	Low Cardiac Output Syndrome	17.2%
20	Cardiomegaly	16.9%
21	Postpericardiotomy Syndrome	16.9%
22	Cardiac Hypertrophy	16.9%
23	Rheumatic Heart Disease	16.6%
24	Vascular Diseases	16.4%
25	Heart Block	14.9%
26	Tachycardia	14.9%
27	Tachyarrhythmia	14.9%
28	Aortic Valve Insufficiency	14.8%
29	Restrictive cardiomyopathy	14.8%
30	Endocardial Fibroelastosis	14.8%
31	Heart Rupture, Post-Infarction	14.8%
32	Mitral Valve Insufficiency	14.8%
33	Mitral Valve Stenosis	14.8%
34	Myocarditis	14.8%
35	Pericarditis, Constrictive	14.8%
36	Pulmonary Valve Insufficiency	14.8%
37	Tricuspid Valve Insufficiency	14.8%
38	Tricuspid Valve Stenosis	14.8%
39	Endomyocardial Fibrosis	14.8%
40	Carditis	14.8%
41	Heart Failure, Systolic	14.8%
42	Heart Failure, Diastolic	14.8%
43	Hypertrophic Cardiomyopathy	14.6%
44	Hypertrophic obstructive cardiomyopathy	14.6%
45	Tricuspid Atresia	13.8%
46	Arrhythmogenic Right Ventricular Dysplasia	13.8%
47	Coronary heart disease	13.2%
48	Myocardial Infarction	13.2%
49	Myocardial Reperfusion Injury	13.2%
50	Acute Coronary Syndrome	13.2%
51	Supravalvular aortic stenosis	12.9%
52	Lown-Ganong-Levine Syndrome	12.9%
53	Long QT Syndrome	11.8%
54	Pregnancy Complications, Cardiovascular	10.8%
55	Cardiovascular Abnormalities	10.8%
56	Kounis Syndrome	10.1%
57	Sinus Arrhythmia	9.9%
58	Atrial Fibrillation	9.9%
59	Atrial Flutter	9.9%
60	Edema, Cardiac	9.9%
61	Ventricular Fibrillation	9.9%
62	Ventricular Flutter	9.9%
63	Parasystole	9.9%
64	Paroxysmal atrial fibrillation	9.9%
65	Bradycardia	9.9%
66	Diabetic Cardiomyopathies	9.9%
67	Aortic coarctation	9.8%
68	Cor Triatriatum	9.8%
69	Coronary Vessel Anomalies	9.8%
70	Patent ductus arteriosus	9.8%
71	Ebstein Anomaly	9.8%
72	Heart Septal Defects	9.8%
73	Tetralogy of Fallot	9.8%
74	Transposition of Great Vessels	9.8%
75	Hypoplastic Left Heart Syndrome	9.8%
76	Angina Pectoris	9.8%
77	Cardiomyopathy, Alcoholic	9.8%
78	Sudden Cardiac Death	9.8%
79	Left Ventricular Hypertrophy	9.8%
80	Right Ventricular Hypertrophy	9.8%
81	Chagas Cardiomyopathy	9.7%
82	Carcinoid Heart Disease	9.7%
83	Adams-Stokes Syndrome	9.7%
84	Aortic Valve Prolapse	9.7%
85	Atrioventricular Block	9.7%
86	Bundle-Branch Block	9.7%
87	Atrial Premature Complexes	9.7%
88	Sick Sinus Syndrome	9.7%
89	Sinoatrial Block	9.7%
90	Tachycardia, Paroxysmal	9.7%
91	Supraventricular tachycardia	9.7%
92	Tricuspid Valve Prolapse	9.7%
93	Tachycardia, Ventricular	9.7%
94	Wolff-Parkinson-White Syndrome	9.7%
95	Tachycardia, Reciprocating	9.7%
96	Bacterial Endocarditis	9.5%
97	Coronary Aneurysm	8.9%
98	Coronary Occlusion	8.6%
99	Microvascular Angina	8.6%
100	Coronary Stenosis	8.6%
101	ST segment elevation myocardial infarction	8.6%
102	Aneurysm	8.5%
103	Angiomatosis	8.5%
104	Aortic Diseases	8.5%
105	Arterial Occlusive Diseases	8.5%
106	Hyperemia	8.5%
107	Hypotension	8.5%
108	Superior Vena Cava Syndrome	8.5%
109	Telangiectasis	8.5%
110	Vasculitis	8.5%
111	Venous Insufficiency	8.5%
112	Peripheral Vascular Diseases	8.5%
113	Embolism and Thrombosis	8.5%
114	Angiodysplasia	8.5%
115	Capillary Leak Syndrome	8.5%
116	Prehypertension	8.5%
117	Coronary Thrombosis	8.1%
118	Coronary Artery Disease	8.1%
119	Dextrocardia	7.9%
120	Romano-Ward Syndrome	7.7%
121	Dyspnea, Paroxysmal	7.4%
122	Tachycardia, Atrioventricular Nodal Reentry	7.2%
123	Tachycardia, Ectopic Atrial	7.2%
124	Tachycardia, Ectopic Junctional	7.2%
125	Sinus Tachycardia	7.2%
126	Torsades de Pointes	7.2%
127	Accelerated Idioventricular Rhythm	7.2%
128	Aortic Aneurysm	6.6%
129	Aortitis	6.6%
130	Leriche Syndrome	6.6%
131	Periphlebitis	6.6%
132	Phlebitis	6.6%
133	Thromboangiitis Obliterans	6.6%
134	Shock, Cardiogenic	6.5%
135	Sinus Arrest, Cardiac	6.5%
136	Aortopulmonary Septal Defect	6.4%
137	Double Outlet Right Ventricle	6.4%
138	Endocardial Cushion Defects	6.4%
139	Myocardial bridging	6.4%
140	Aorticopulmonary Septal Defect	6.4%
141	Angina, Unstable	6.4%
142	Coronary Restenosis	6.4%
143	Vascular System Injuries	6%
144	Embolism, Amniotic Fluid	5.8%
145	Compartment syndromes	5.7%
146	Hepatic Veno-Occlusive Disease	5.7%
147	Peliosis Hepatis	5.7%
148	Varicocele	5.7%
149	Noonan Syndrome	5.7%
150	Cerebrovascular Disorders	5.6%
151	Diabetic Angiopathies	5.6%
152	Reperfusion Injury	5.6%
153	Splenic Infarction	5.6%
154	Cerebrovascular Insufficiency	5.6%
155	Vascular Neoplasms	5.6%
156	Spinal Cord Vascular Diseases	5.6%
157	Vasoplegia	5.6%
158	Hemorrhoids	5.6%
159	Thoracic Outlet Syndrome	5.6%
160	Retinal Vein Occlusion	5.5%
161	Postphlebitic Syndrome	5.4%
162	Marfan Syndrome	5%
163	Malignant Atrophic Papulosis	5%
164	Aneurysm, Dissecting	4.9%
165	Arteriosclerosis	4.9%
166	Arteritis	4.9%
167	Embolism	4.9%
168	Erythromelalgia	4.9%
169	Fibromuscular Dysplasia	4.9%
170	Malignant Hypertension	4.9%
171	Raynaud Disease	4.9%
172	Shwartzman Phenomenon	4.9%
173	Thromboembolism	4.9%
174	Thrombosis	4.9%
175	Essential Hypertension	4.9%
176	Aneurysm, Ruptured	4.9%
177	Iliac Aneurysm	4.9%
178	Pulmonary artery stenosis	4.9%
179	White Coat Hypertension	4.9%
180	Systemic Vasculitis	4.9%
181	Embolus	4.9%
182	May-Thurner Syndrome	4.9%
183	Subacute Bacterial Endocarditis	4.9%
184	Truncus Arteriosus, Persistent	4.8%
185	Angina Pectoris, Variant	4.8%
186	Arteriovenous fistula	4.6%
187	Blue Toe Syndrome	4.6%
188	Hand-Arm Vibration Syndrome	4.4%
189	Thrombophlebitis	4.4%
190	Aortic Aneurysm, Abdominal	4.3%
191	Aortic Aneurysm, Thoracic	4.3%
192	Optic Neuropathy, Ischemic	4.3%
193	Anterior Ischemic Optic Neuropathy	4.3%
194	Mesenteric vascular insufficiency	4.3%
195	Angioedema	4.1%
196	Colitis, Ischemic	4.1%
197	Intracranial Embolism and Thrombosis	4.1%
198	Carotid Stenosis	4%
199	Intracranial Aneurysm	4%
200	Aortic Rupture	3.9%
201	Scimitar Syndrome	3.9%
202	Carotid Artery Thrombosis	3.5%
203	Moyamoya Disease	3.5%
204	Retinal Artery Occlusion	3.4%
205	Retinal Vasculitis	3.4%
206	Hypertensive Retinopathy	3.4%
207	Vasculitis, Central Nervous System	3.3%
208	Anterior Compartment Syndrome	3.3%
209	Vasculitis, Leukocytoclastic, Cutaneous	3.3%
210	Gastric Antral Vascular Ectasia	3.3%
211	Abdominal Compartment Syndrome	3.3%
212	Carotid Artery Diseases	3.3%
213	Brain Ischemia	3.3%
214	Ectopia Cordis	3.3%
215	Hypotension, Orthostatic	3.3%
216	Cerebrovascular accident	3.3%
217	Varicose Ulcer	3.3%
218	Vasospasm, Intracranial	3.3%
219	Spinal Cord Ischemia	3.3%
220	Intracranial Arterial Diseases	3.3%
221	Primary Graft Dysfunction	3.3%
222	Single umbilical artery	3.3%
223	Post-Exercise Hypotension	3.3%
224	Polyarteritis Nodosa	3.3%
225	Takayasu Arteritis	3.3%
226	Arteriosclerosis Obliterans	3.2%
227	Atherosclerosis	3.2%
228	Air Embolism	3.2%
229	Endarteritis	3.2%
230	Venous Thrombosis	3.2%
231	Deep Vein Thrombosis	3.2%
232	Venous Thromboembolism	3.2%
233	Intracranial Arteriosclerosis	3.2%
234	Cerebral Atherosclerosis	3.2%
235	Cerebral Arteriosclerosis	3.2%
236	Williams Syndrome	2.9%
237	Cerebral Thrombosis	2.8%
238	Intracranial Embolism	2.8%
239	Intracranial Thrombosis	2.8%
240	Turner Syndrome	2.8%
241	Kearns-Sayre syndrome	2.6%
242	Brain Infarction	2.6%
243	Mesenteric Vascular Occlusion	2.5%
244	Mucocutaneous Lymph Node Syndrome	2.5%
245	Diabetic Retinopathy	2.5%
246	Sturge-Weber Syndrome	2.5%
247	Livedo Reticularis	2.5%
248	Renal hypertension	2.5%
249	Renal Artery Obstruction	2.5%
250	Renal Artery Stenosis	2.5%
251	Hemangioma, Cavernous	2.4%
252	Basal Ganglia Cerebrovascular Disease	2.4%
253	Giant Cell Arteritis	2.4%
254	Temporal Arteritis	2.4%
255	Vascular Headaches	2.4%
256	Scurvy	2.4%
257	CREST Syndrome	2.3%
258	Intermittent Claudication	2.2%
259	Pulmonary Embolism	2.2%
260	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.2%
261	Sinus Thrombosis, Intracranial	2.2%
262	No-Reflow Phenomenon	2.2%
263	Vertebral Artery Dissection	2.2%
264	Cerebral Arterial Diseases	2.1%
265	Vertebrobasilar Insufficiency	2.1%
266	Anterior Spinal Artery Syndrome	2.1%
267	Basilar Artery Stenosis	2.1%
268	Vertebral Artery Stenosis	2.1%
269	Intracranial Hemorrhage, Hypertensive	2.1%
270	Transient Cerebral Ischemia	2.1%
271	Kartagener Syndrome	2.1%
272	Dural Arteriovenous Fistula	2%
273	Subarachnoid Hemorrhage, Traumatic	2%
274	Carotid Artery, Internal, Dissection	2%
275	Lemierre Syndrome	2%
276	Ischemic contracture	2%
277	Angioedemas, Hereditary	2%
278	Cryoglobulinemia	2%
279	Leukomalacia, Periventricular	2%
280	Diabetic Foot	1.9%
281	Cerebral Infarction	1.9%
282	Brain Stem Infarctions	1.9%
283	Cavernous Sinus Thrombosis	1.9%
284	Sagittal Sinus Thrombosis	1.9%
285	Carotid Artery Injuries	1.9%
286	Infarction, Middle Cerebral Artery	1.8%
287	Infarction, Anterior Cerebral Artery	1.8%
288	Infarction, Posterior Cerebral Artery	1.8%
289	Hepatic Vein Thrombosis	1.7%
290	Budd-Chiari Syndrome	1.7%
291	Shy-Drager Syndrome	1.6%
292	Pulmonary Infarction	1.6%
293	Purpura, Hyperglobulinemic	1.6%
294	Hypertension, Renovascular	1.6%
295	Subarachnoid Hemorrhage	1.6%
296	Hypoxia-Ischemia, Brain	1.6%
297	Cerebral Hemorrhage	1.6%
298	Hereditary Angioedema Type III	1.6%
299	Hereditary Angioedema Types I and II	1.6%
300	Basal Ganglia Hemorrhage	1.6%
301	Subclavian Steal Syndrome	1.6%
302	Lateral Medullary Syndrome	1.6%
303	Behcet Syndrome	1.4%
304	Waldenstrom Macroglobulinemia	1.4%
305	Multiple Myeloma	1.4%
306	Pituitary Apoplexy	1.3%
307	Ataxia Telangiectasia	1.3%
308	Pseudoxanthoma Elasticum	1.3%
309	Putaminal Hemorrhage	1.2%
310	Granulomatosis with polyangiitis	1.2%
311	Dementia, Vascular	1.2%
312	Cerebral Amyloid Angiopathy	1.2%
313	Rheumatoid Vasculitis	1.1%
314	Lupus Vasculitis, Central Nervous System	1.1%
315	Hematoma, Subdural	0.7%
316	Hematoma, Epidural, Cranial	0.7%
317	MELAS Syndrome	0.6%
318	Brain Hemorrhage, Traumatic	0.6%
319	Hematoma, Subdural, Intracranial	0.6%
320	Hematoma, Subdural, Chronic	0.6%
321	Hematoma, Subdural, Acute	0.6%
322	Fabry Disease	0.5%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234