MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

No-Reflow Phenomenon

(UMLS:C0232347)

Definition:: Markedly reduced or absent REPERFUSION in an infarct zone following the removal of an obstruction or constriction of an artery.
UMLS ID:: C0232347
MeSH ID:: D054318

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.585.500.562

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.513.677

Synonym(s)

No-Reflow Phenomenon

No reflow phenomenon

No reflow vascular flow

Vascular flow, no reflow

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Carvedilol		16824628 18840580	CTD
2	Eptifibatide		16327040	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Infarction	33.1%
2	Shock, Cardiogenic	28.8%
3	ST segment elevation myocardial infarction	26%
4	Reperfusion Injury	22.7%
5	Vasoplegia	22.7%
6	Myocardial Reperfusion Injury	21.2%
7	Polydipsia	20.5%
8	Ascites	20.2%
9	Fibrosis	20.2%
10	Gliosis	20.2%
11	Growth Disorders	20.2%
12	Hemorrhage	20.2%
13	Hyperbilirubinemia	20.2%
14	Hyperplasia	20.2%
15	Hypomenorrhea	20.2%
16	Inflammation	20.2%
17	Intraoperative Complications	20.2%
18	Lithiasis	20.2%
19	Malacoplakia	20.2%
20	Menstruation Disturbances	20.2%
21	Metaplasia	20.2%
22	Nerve Degeneration	20.2%
23	Ochronosis	20.2%
24	Polymenorrhea	20.2%
25	Postoperative Complications	20.2%
26	Sclerosis	20.2%
27	Shock	20.2%
28	Ulcer	20.2%
29	Hyperammonemia	20.2%
30	Hyperamylasemia	20.2%
31	Teratogenesis	20.2%
32	Cardiac Death	20.2%
33	Hypovolemia	20.2%
34	Hyperuricemia	20.2%
35	Leukoaraiosis	20.2%
36	Dysbacteriosis	20.2%
37	Delayed Graft Function	20.2%
38	Cirrhosis	20.2%
39	Neointima	20.2%
40	Dysbiosis	20.2%
41	Coronary heart disease	19.8%
42	Postoperative Hemorrhage	19.8%
43	Shock, Hemorrhagic	19.8%
44	Systemic Inflammatory Response Syndrome	19.8%
45	Acute Coronary Syndrome	19.8%
46	Angina Pectoris	17.4%
47	Aneurysm	16.9%
48	Angiomatosis	16.9%
49	Aortic Diseases	16.9%
50	Arterial Occlusive Diseases	16.9%
51	Hyperemia	16.9%
52	Hypotension	16.9%
53	Superior Vena Cava Syndrome	16.9%
54	Telangiectasis	16.9%
55	Vasculitis	16.9%
56	Venous Insufficiency	16.9%
57	Peripheral Vascular Diseases	16.9%
58	Embolism and Thrombosis	16.9%
59	Angiodysplasia	16.9%
60	Capillary Leak Syndrome	16.9%
61	Prehypertension	16.9%
62	Vascular Remodeling	16.6%
63	Coronary Aneurysm	16.3%
64	Kounis Syndrome	16.1%
65	Extravasation of Diagnostic and Therapeutic Materials	15.9%
66	Neoplastic Processes	15.9%
67	Necrosis	15.4%
68	Granulomatosis, Orofacial	15.4%
69	Pigmentation Disorders	15.4%
70	Respiratory Aspiration	15.4%
71	Acantholysis	15.1%
72	Chromosome Aberrations	15.1%
73	Dehydration	15.1%
74	Granuloma	15.1%
75	Leukocytosis	15.1%
76	Pleocytosis	15.1%
77	Aortic Aneurysm	14.9%
78	Aortitis	14.9%
79	Leriche Syndrome	14.9%
80	Periphlebitis	14.9%
81	Phlebitis	14.9%
82	Thromboangiitis Obliterans	14.9%
83	Primary Graft Dysfunction	14.8%
84	Sudden infant death syndrome	14.6%
85	Coronary Thrombosis	14.3%
86	Postpericardiotomy Syndrome	14.3%
87	Coronary Artery Disease	14.3%
88	Menorrhagia	13.7%
89	Chromosomal Instability	13.3%
90	Vascular System Injuries	13.3%
91	Incisional hernia	13.2%
92	jaundice	13.2%
93	Acute Disease	13.2%
94	Acute-Phase Reaction	13.2%
95	Amenorrhea	13.2%
96	Chronic disease	13.2%
97	Critical Illness	13.2%
98	Sudden death	13.2%
99	Fat necrosis	13.2%
100	Gangrene	13.2%
101	Graft Occlusion, Vascular	13.2%
102	Granuloma, Plasma Cell	13.2%
103	Hematoma	13.2%
104	Iatrogenic Disease	13.2%
105	Multiple Organ Failure	13.2%
106	Oligomenorrhea	13.2%
107	Premenstrual syndrome	13.2%
108	Recurrence	13.2%
109	Retrograde Degeneration	13.2%
110	Retroperitoneal fibrosis	13.2%
111	Serositis	13.2%
112	Subcutaneous Emphysema	13.2%
113	Surgical Wound Dehiscence	13.2%
114	Syndrome	13.2%
115	Wallerian Degeneration	13.2%
116	Pyogenic granuloma	13.2%
117	Exsanguination	13.2%
118	Disease Progression	13.2%
119	Seroma	13.2%
120	Premenstrual Tension	13.2%
121	Delayed Emergence from Anesthesia	13.2%
122	Infant Death	13.2%
123	Anastomotic Leak	13.2%
124	Intraoperative Awareness	13.2%
125	Retinal Vein Occlusion	13.1%
126	Coronary Occlusion	13%
127	Microvascular Angina	13%
128	Coronary Stenosis	13%
129	Compartment syndromes	12.8%
130	Hepatic Veno-Occlusive Disease	12.8%
131	Peliosis Hepatis	12.8%
132	Varicocele	12.8%
133	Cerebrovascular Disorders	12.6%
134	Diabetic Angiopathies	12.6%
135	Splenic Infarction	12.6%
136	Cerebrovascular Insufficiency	12.6%
137	Vascular Neoplasms	12.6%
138	Spinal Cord Vascular Diseases	12.6%
139	Genomic Instability	12.6%
140	Hemorrhoids	12.5%
141	Thoracic Outlet Syndrome	12.5%
142	Sinus Arrhythmia	12.4%
143	Atrial Fibrillation	12.4%
144	Atrial Flutter	12.4%
145	Ventricular Fibrillation	12.4%
146	Ventricular Flutter	12.4%
147	Parasystole	12.4%
148	Paroxysmal atrial fibrillation	12.4%
149	Bradycardia	12.4%
150	Pain, Postoperative	12.3%
151	Postphlebitic Syndrome	12.3%
152	Heart Block	11.9%
153	Tachycardia	11.9%
154	Tachyarrhythmia	11.9%
155	Malignant Atrophic Papulosis	11.9%
156	Azotemia	11.9%
157	Shwartzman Phenomenon	11.8%
158	Dysmenorrhea	11.8%
159	Failed Back Surgery Syndrome	11.8%
160	Muscle Weakness	11.8%
161	Angina, Unstable	11.8%
162	Signs and Symptoms	11.8%
163	Postoperative Nausea and Vomiting	11.8%
164	Pathological Conditions, Anatomical	11.8%
165	Sick Sinus Syndrome	11.1%
166	Eye Hemorrhage	11%
167	Endotoxic shock	10.7%
168	Septic Shock	10.7%
169	Toxic Shock Syndrome	10.7%
170	Hemoptysis	10.7%
171	Thrombophlebitis	10.7%
172	Ecchymosis	10.6%
173	Petechiae	10.6%
174	Purpura	10.6%
175	Heart Diseases	10.6%
176	Hand-Arm Vibration Syndrome	10.5%
177	Asphyxia	10.4%
178	Granuloma, Respiratory Tract	10.4%
179	Shock, Traumatic	10.4%
180	Blue Toe Syndrome	10.4%
181	Cardiotoxicity	10.2%
182	Optic Neuropathy, Ischemic	10.2%
183	Anterior Ischemic Optic Neuropathy	10.2%
184	Mesenteric vascular insufficiency	10.2%
185	Arteriovenous fistula	10.2%
186	Disease susceptibility	10.1%
187	Fetal Death	10.1%
188	Foreign-Body Reaction	10.1%
189	Gastrointestinal Hemorrhage	10.1%
190	Hemarthrosis	10.1%
191	Hemoperitoneum	10.1%
192	Hemothorax	10.1%
193	Neoplasm Invasiveness	10.1%
194	Neoplasm Metastasis	10.1%
195	Neoplasm Recurrence, Local	10.1%
196	Prosthesis Failure	10.1%
197	Injection Site Reaction	10.1%
198	Retrobulbar Hemorrhage	10.1%
199	Aseptic Necrosis of Bone	10.1%
200	Peritoneal Fibrosis	10.1%
201	Carcinogenesis	10.1%
202	Neurogenic Inflammation	10.1%
203	Perinatal death	10.1%
204	Infusion site reaction	10.1%
205	Nephrogenic Fibrosing Dermopathy	10.1%
206	Corneal Endothelial Cell Loss	10.1%
207	Encapsulating Peritoneal Sclerosis	10.1%
208	Suppuration	10.1%
209	Nephrogenic Systemic Fibrosis	10.1%
210	Metastasis	10.1%
211	Intermittent Claudication	10%
212	Angioedema	9.9%
213	Dental Pulp Necrosis	9.9%
214	Granuloma, Foreign-Body	9.9%
215	Mediastinal Emphysema	9.9%
216	Surgical Wound Infection	9.9%
217	Facies	9.9%
218	Embryo Loss	9.9%
219	Colitis, Ischemic	9.9%
220	Aneurysm, Dissecting	9.9%
221	Aortic Rupture	9.9%
222	Arteriosclerosis	9.9%
223	Arteritis	9.9%
224	Embolism	9.9%
225	Erythromelalgia	9.9%
226	Fibromuscular Dysplasia	9.9%
227	Malignant Hypertension	9.9%
228	Long QT Syndrome	9.9%
229	Raynaud Disease	9.9%
230	Thromboembolism	9.9%
231	Thrombosis	9.9%
232	Essential Hypertension	9.9%
233	Aneurysm, Ruptured	9.9%
234	Iliac Aneurysm	9.9%
235	Pulmonary artery stenosis	9.9%
236	White Coat Hypertension	9.9%
237	Systemic Vasculitis	9.9%
238	Embolus	9.9%
239	Afferent Loop Syndrome	9.8%
240	Sex Chromosome Aberrations	9.8%
241	Short Bowel Syndrome	9.8%
242	Uterine hemorrhage	9.8%
243	Sudden Cardiac Death	9.8%
244	Intracranial Embolism and Thrombosis	9.8%
245	Tissue Adhesions	9.8%
246	Hematoma, Epidural, Spinal	9.8%
247	Carotid Stenosis	9.8%
248	Intracranial Aneurysm	9.8%
249	Purpura, Hyperglobulinemic	9.8%
250	Chromosome Fragility	9.8%
251	Jaundice, Obstructive	9.8%
252	Aortic Aneurysm, Abdominal	9.8%
253	Aortic Aneurysm, Thoracic	9.8%
254	Subarachnoid Hemorrhage	9.7%
255	Cerebral Hemorrhage	9.7%
256	Coronary Restenosis	9.7%
257	Cardiac Output, High	9.4%
258	Myocardial Stunning	9.4%
259	Low Cardiac Output Syndrome	9.4%
260	Hematoma, Subdural	9.1%
261	Hematoma, Epidural, Cranial	9.1%
262	Angina Pectoris, Variant	9.1%
263	Epistaxis	9%
264	Moyamoya Disease	9%
265	Sinus Arrest, Cardiac	8.9%
266	Carotid Artery Thrombosis	8.9%
267	Livedo Reticularis	8.6%
268	Vasculitis, Central Nervous System	8.6%
269	Adams-Stokes Syndrome	8.4%
270	Atrioventricular Block	8.4%
271	Bundle-Branch Block	8.4%
272	Atrial Premature Complexes	8.4%
273	Sinoatrial Block	8.4%
274	Tachycardia, Paroxysmal	8.4%
275	Supraventricular tachycardia	8.4%
276	Tachycardia, Ventricular	8.4%
277	Tachycardia, Reciprocating	8.4%
278	Trisomy	8.3%
279	Drowning	8.3%
280	Hematoma, Subdural, Spinal	8.1%
281	Fetal Growth Retardation	8.1%
282	DNA Degradation, Necrotic	8.1%
283	Aneuploidy	8%
284	Polyploidy	8%
285	Microsatellite Instability	8%
286	Pregnancy Complications, Cardiovascular	8%
287	Cardiovascular Abnormalities	8%
288	Cicatrix	7.9%
289	Hematuria	7.9%
290	Granuloma Annulare	7.9%
291	Chromosome Breakage	7.9%
292	May-Thurner Syndrome	7.9%
293	Brain Death	7.9%
294	Hematemesis	7.8%
295	Polyarteritis Nodosa	7.8%
296	Takayasu Arteritis	7.8%
297	Purpura Fulminans	7.8%
298	Intracranial Arteriosclerosis	7.8%
299	Cerebral Atherosclerosis	7.8%
300	Cerebral Arteriosclerosis	7.8%
301	Scimitar Syndrome	7.6%
302	Cardiomegaly	7.6%
303	Retinal Artery Occlusion	7.6%
304	Retinal Vasculitis	7.6%
305	Hypertensive Retinopathy	7.6%
306	Cardiac Hypertrophy	7.6%
307	Cross Infection	7.5%
308	Hyphema	7.5%
309	Retinal Neovascularization	7.5%
310	Septicemia	7.5%
311	Vitreous Hemorrhage	7.5%
312	Sepsis	7.5%
313	Hematoma, Subdural, Intracranial	7.5%
314	Hematoma, Subdural, Chronic	7.5%
315	Hematoma, Subdural, Acute	7.5%
316	Anterior Compartment Syndrome	7.4%
317	Vasculitis, Leukocytoclastic, Cutaneous	7.4%
318	Gastric Antral Vascular Ectasia	7.4%
319	Abdominal Compartment Syndrome	7.4%
320	Abscess	7.4%
321	Carotid Artery Diseases	7.4%
322	Brain Ischemia	7.4%
323	Empyema	7.4%
324	Femur Head Necrosis	7.4%
325	Fetal Resorption	7.4%
326	Hypotension, Orthostatic	7.4%
327	Lymphatic Metastasis	7.4%
328	Neoplasms, Unknown Primary	7.4%
329	Peptic Ulcer Hemorrhage	7.4%
330	Cerebrovascular accident	7.4%
331	Varicose Ulcer	7.4%
332	Leukemic Infiltration	7.4%
333	Premenstrual Dysphoric Disorder	7.4%
334	Choroidal Neovascularization	7.4%
335	Vasospasm, Intracranial	7.4%
336	Spinal Cord Ischemia	7.4%
337	Intracranial Arterial Diseases	7.4%
338	Neoplasm Micrometastasis	7.4%
339	Post-Exercise Hypotension	7.4%
340	Embolism, Amniotic Fluid	7.3%
341	Dumping Syndrome	7.3%
342	Cicatrix, Hypertrophic	7.3%
343	Metrorrhagia	7.3%
344	Basal Ganglia Hemorrhage	7.2%
345	Romano-Ward Syndrome	7%
346	Cerebral Thrombosis	6.8%
347	Intracranial Embolism	6.8%
348	Intracranial Thrombosis	6.8%
349	Tachycardia, Atrioventricular Nodal Reentry	6.8%
350	Tachycardia, Ectopic Atrial	6.8%
351	Tachycardia, Ectopic Junctional	6.8%
352	Sinus Tachycardia	6.8%
353	Torsades de Pointes	6.8%
354	Accelerated Idioventricular Rhythm	6.8%
355	Asthenia	6.7%
356	Body Temperature Changes	6.7%
357	Calculi	6.7%
358	Cyanosis	6.7%
359	Edema	6.7%
360	Giant Cell Epulis	6.7%
361	Failure to Thrive	6.7%
362	Fatigue	6.7%
363	Feminization	6.7%
364	Fetal Distress	6.7%
365	Hernia	6.7%
366	Hypertrophy	6.7%
367	Motion Sickness	6.7%
368	Nails, Malformed	6.7%
369	polyps	6.7%
370	Rupture, Spontaneous	6.7%
371	Signs and Symptoms, Digestive	6.7%
372	Signs and Symptoms, Respiratory	6.7%
373	Skin Manifestations	6.7%
374	Chills	6.7%
375	Lassitude	6.7%
376	Enterocele	6.7%
377	Atheroma	6.7%
378	Pseudophakia	6.7%
379	Urological Manifestations	6.7%
380	Stenosis	6.7%
381	Facial asymmetry	6.7%
382	Mobility Limitation	6.7%
383	Somnolence	6.7%
384	Plaque, Amyloid	6.7%
385	Plaque, Atherosclerotic	6.7%
386	Arteriosclerosis Obliterans	6.5%
387	Atherosclerosis	6.5%
388	Air Embolism	6.5%
389	Endarteritis	6.5%
390	Venous Thrombosis	6.5%
391	Deep Vein Thrombosis	6.5%
392	Venous Thromboembolism	6.5%
393	Giant Cell Arteritis	6.5%
394	Temporal Arteritis	6.5%
395	Micronuclei, Chromosome-Defective	6.5%
396	Phantom pain	6.5%
397	Phantom Limb Pain	6.5%
398	Brain Infarction	6.5%
399	Viremia	6.4%
400	Parasitemia	6.4%
401	CREST Syndrome	6.1%
402	Retinal Hemorrhage	6.1%
403	Mesenteric Vascular Occlusion	6%
404	Mucocutaneous Lymph Node Syndrome	6%
405	Choroid Hemorrhage	6%
406	Diabetic Retinopathy	6%
407	Melena	6%
408	Sturge-Weber Syndrome	6%
409	Putaminal Hemorrhage	6%
410	Renal hypertension	5.9%
411	Postpartum Hemorrhage	5.9%
412	Renal Artery Obstruction	5.9%
413	Renal Artery Stenosis	5.9%
414	Gingival Hemorrhage	5.9%
415	Hemangioma, Cavernous	5.9%
416	Keloid	5.9%
417	Basal Ganglia Cerebrovascular Disease	5.9%
418	Monosomy	5.9%
419	Vascular Headaches	5.9%
420	Tetraploidy	5.9%
421	Stillbirth	5.9%
422	Scurvy	5.9%
423	Edema, Cardiac	5.8%
424	Subacute Combined Degeneration	5.7%
425	Abdominal Pain	5.7%
426	Thrombocytopenic purpura	5.7%
427	Eosinophilic Granuloma	5.7%
428	Cardiac Tamponade	5.6%
429	Endocarditis	5.6%
430	Cardiac Arrest	5.6%
431	Heart failure	5.6%
432	Pericardial effusion	5.6%
433	Pericarditis	5.6%
434	Pneumopericardium	5.6%
435	Cor pulmonale	5.6%
436	Ventricular Outflow Obstruction	5.6%
437	Ventricular Dysfunction	5.6%
438	Cardiomyopathies	5.6%
439	Pleuropericarditis	5.6%
440	Vertebral Artery Dissection	5.6%
441	Subarachnoid Hemorrhage, Traumatic	5.3%
442	Carotid Artery, Internal, Dissection	5.3%
443	Cyst	5.3%
444	Eye Manifestations	5.3%
445	Neurologic Manifestations	5.3%
446	Sinus Thrombosis, Intracranial	5.3%
447	Lemierre Syndrome	5.2%
448	Leukoplakia	5.1%
449	Reticulocytosis	5.1%
450	Airway Remodeling	5.1%
451	Ventricular Remodeling	5%
452	Alopecia	5%
453	Cellulitis	5%
454	Kernicterus	5%
455	Pulmonary Embolism	5%
456	Androgenetic Alopecia	5%
457	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5%
458	Bacteremia	5%
459	Ischemic contracture	5%
460	Aortic Valve Stenosis	5%
461	Cardiomyopathy, Dilated	5%
462	Pulmonary Valve Stenosis	5%
463	Cell Transformation, Viral	5%
464	Angioedemas, Hereditary	4.9%
465	Renal Colic	4.9%
466	Tricuspid Atresia	4.9%
467	Arrhythmogenic Right Ventricular Dysplasia	4.9%
468	Cryoglobulinemia	4.9%
469	Leukomalacia, Periventricular	4.9%
470	Fungemia	4.9%
471	Left Ventricular Hypertrophy	4.9%
472	Right Ventricular Hypertrophy	4.9%
473	Carotid Artery Injuries	4.9%
474	Diabetic Foot	4.9%
475	Cerebral Arterial Diseases	4.9%
476	Vertebrobasilar Insufficiency	4.9%
477	Anterior Spinal Artery Syndrome	4.9%
478	Basilar Artery Stenosis	4.9%
479	Vertebral Artery Stenosis	4.9%
480	Intracranial Hemorrhage, Hypertensive	4.9%
481	Transient Cerebral Ischemia	4.9%
482	Cerebral Infarction	4.8%
483	Brain Stem Infarctions	4.8%
484	Infarction, Middle Cerebral Artery	4.8%
485	Infarction, Anterior Cerebral Artery	4.8%
486	Infarction, Posterior Cerebral Artery	4.8%
487	Eye pain	4.7%
488	Muscular Atrophy	4.6%
489	Purpura, Thrombotic Thrombocytopenic	4.6%
490	Cavernous Sinus Thrombosis	4.6%
491	Sagittal Sinus Thrombosis	4.6%
492	Bacterial Endocarditis	4.5%
493	Abdomen, Acute	4.5%
494	Anorexia	4.4%
495	Anoxia	4.4%
496	Constipation	4.4%
497	Diarrhea	4.4%
498	Dyspepsia	4.4%
499	Eructation	4.4%
500	Fever	4.4%
501	Flatulence	4.4%
502	Flushing	4.4%
503	Halitosis	4.4%
504	Heartburn	4.4%
505	Diaphragmatic Hernia	4.4%
506	Hiccough	4.4%
507	Hypercalciuria	4.4%
508	Hypercapnia	4.4%
509	Hyperphagia	4.4%
510	Intestinal Polyps	4.4%
511	Nausea	4.4%
512	Pallor	4.4%
513	Psychophysiologic Disorders	4.4%
514	Splenomegaly	4.4%
515	Vomiting	4.4%
516	Hypocapnia	4.4%
517	Dyschezia	4.4%
518	Hypoxia	4.4%
519	Hyperoxia	4.4%
520	Lower Urinary Tract Symptoms	4.4%
521	Hypoxemia	4.4%
522	Urinoma	4.4%
523	Endotoxemia	4.4%
524	Granuloma, Laryngeal	4.4%
525	Myocardial Ischemia	4.3%
526	Shy-Drager Syndrome	4.2%
527	Rheumatic Heart Disease	4.1%
528	Hypergammaglobulinemia	4.1%
529	Lateral Medullary Syndrome	4%
530	Diverticulum	4%
531	Diverticulosis	4%
532	Aortic coarctation	3.9%
533	Cor Triatriatum	3.9%
534	Coronary Vessel Anomalies	3.9%
535	Patent ductus arteriosus	3.9%
536	Dyspnea, Paroxysmal	3.9%
537	Ebstein Anomaly	3.9%
538	Heart Septal Defects	3.9%
539	Tetralogy of Fallot	3.9%
540	Transposition of Great Vessels	3.9%
541	Hypoplastic Left Heart Syndrome	3.9%
542	Hypertension, Renovascular	3.9%
543	Hypoxia-Ischemia, Brain	3.9%
544	Hereditary Angioedema Type III	3.9%
545	Hereditary Angioedema Types I and II	3.9%
546	Hepatic Vein Thrombosis	3.7%
547	Budd-Chiari Syndrome	3.7%
548	Behcet Syndrome	3.7%
549	Waldenstrom Macroglobulinemia	3.7%
550	Multiple Myeloma	3.7%
551	Hypertrophic Cardiomyopathy	3.7%
552	Pulmonary Infarction	3.7%
553	Hypertrophic obstructive cardiomyopathy	3.7%
554	Autoimmune thrombocytopenia	3.7%
555	Immune thrombocytopenic purpura	3.7%
556	Subclavian Steal Syndrome	3.6%
557	Philadelphia Chromosome	3.6%
558	Sarcopenia	3.6%
559	Waterhouse-Friderichsen Syndrome	3.5%
560	Respiratory Tract Fistula	3.5%
561	Apnea	3.4%
562	Cheyne-Stokes Respiration	3.4%
563	Decerebrate State	3.4%
564	Dyspnea	3.4%
565	Hemiparesis	3.4%
566	Hepatomegaly	3.4%
567	Hyperventilation	3.4%
568	Meningism	3.4%
569	Mouth Breathing	3.4%
570	Paresis	3.4%
571	Parovarian Cyst	3.4%
572	Pruritus	3.4%
573	Seizures	3.4%
574	Sensation Disorders	3.4%
575	Sneezing	3.4%
576	Spermatocele	3.4%
577	Erythema	3.4%
578	Oral Fistula	3.4%
579	Complex partial seizures	3.4%
580	Necrolytic Migratory Erythema	3.4%
581	Tachypnea	3.4%
582	Monoparesis	3.4%
583	Cutaneous Fistula	3.4%
584	Gait Disorders, Neurologic	3.4%
585	Neuromuscular Manifestations	3.4%
586	Ataxia Telangiectasia	3.4%
587	Pseudoxanthoma Elasticum	3.3%
588	Mental Fatigue	3.3%
589	Hirsutism	3.3%
590	Orthostatic intolerance	3.3%
591	Hypoventilation	3.3%
592	Aortic Valve Insufficiency	3.3%
593	Restrictive cardiomyopathy	3.3%
594	Dextrocardia	3.3%
595	Endocardial Fibroelastosis	3.3%
596	Heart Rupture, Post-Infarction	3.3%
597	Mitral Valve Insufficiency	3.3%
598	Mitral Valve Stenosis	3.3%
599	Myocarditis	3.3%
600	Pericarditis, Constrictive	3.3%
601	Pulmonary Valve Insufficiency	3.3%
602	Tricuspid Valve Insufficiency	3.3%
603	Tricuspid Valve Stenosis	3.3%
604	Ventricular Dysfunction, Left	3.3%
605	Right Ventricular Dysfunction	3.3%
606	Endomyocardial Fibrosis	3.3%
607	Carditis	3.3%
608	Heart Failure, Systolic	3.3%
609	Heart Failure, Diastolic	3.3%
610	Pituitary Apoplexy	3.3%
611	Vaginal Fistula	3.3%
612	Rectocele	3.3%
613	Body Weight Changes	3.3%
614	Back Pain	3.3%
615	Bulimia	3.3%
616	Neck Pain	3.3%
617	Chest Pain	3.3%
618	Colonic Polyps	3.3%
619	Dizziness	3.3%
620	Dysuria	3.3%
621	Facial Pain	3.3%
622	Fever of Unknown Origin	3.3%
623	Flank Pain	3.3%
624	Headache	3.3%
625	Nocturia	3.3%
626	Pain, Intractable	3.3%
627	Pelvic Pain	3.3%
628	Snoring	3.3%
629	Chronic pain	3.3%
630	Lightheadedness	3.3%
631	Pain, Referred	3.3%
632	Prostatism	3.3%
633	Throbbing Headache	3.3%
634	Labor Pain	3.3%
635	Cancer Pain	3.3%
636	Nociceptive Pain	3.3%
637	Supravalvular aortic stenosis	3.3%
638	Lown-Ganong-Levine Syndrome	3.3%
639	Dementia, Vascular	3.2%
640	Candidemia	3.1%
641	Lupus Vasculitis, Central Nervous System	3%
642	Gait Ataxia	3%
643	Granulomatosis with polyangiitis	3%
644	Hoarseness	2.9%
645	Cerebral Amyloid Angiopathy	2.9%
646	Sleep Wake Disorders	2.9%
647	Body Weight	2.8%
648	Rheumatoid Vasculitis	2.8%
649	Pupil Disorders	2.8%
650	Neurobehavioral Manifestations	2.8%
651	Nasal Polyps	2.7%
652	Carcinoid Heart Disease	2.7%
653	Emaciation	2.7%
654	Low Back Pain	2.7%
655	Visceral Pain	2.7%
656	Pleural Rub	2.7%
657	Rales	2.7%
658	Respiratory Sounds	2.7%
659	Rhonchi	2.7%
660	Stridor	2.7%
661	Wheezing	2.7%
662	Asterixis	2.7%
663	Ballismus	2.7%
664	Vertigo	2.7%
665	Pain	2.6%
666	Ache	2.6%
667	Meningocele	2.6%
668	Oliguria	2.6%
669	Polyuria	2.6%
670	Proteinuria	2.6%
671	Urinary Calculi	2.6%
672	Encephalocele	2.6%
673	Wolff-Parkinson-White Syndrome	2.6%
674	Underweight	2.6%
675	Overweight	2.6%
676	Aortopulmonary Septal Defect	2.6%
677	Double Outlet Right Ventricle	2.6%
678	Endocardial Cushion Defects	2.6%
679	Myocardial bridging	2.6%
680	Aorticopulmonary Septal Defect	2.6%
681	Akathisia	2.6%
682	Restlessness	2.6%
683	Psychomotor Agitation	2.6%
684	Vesicovaginal Fistula	2.5%
685	Biliary Fistula	2.5%
686	Gastric Fistula	2.5%
687	Congenital diaphragmatic hernia	2.5%
688	Morning Sickness	2.5%
689	Noonan Syndrome	2.5%
690	Myocardial Infarction	2.5%
691	Diabetic Cardiomyopathies	2.5%
692	Anosmia	2.5%
693	Ataxia	2.5%
694	Athetosis	2.5%
695	Cardiomyopathy, Alcoholic	2.5%
696	Catalepsy	2.5%
697	Dental Fistula	2.5%
698	Dystonia	2.5%
699	Ectopia Cordis	2.5%
700	Hemiplegia	2.5%
701	Locked-In Syndrome	2.5%
702	Muscle Hypertonia	2.5%
703	Muscle hypotonia	2.5%
704	Myoclonus	2.5%
705	Myotonia	2.5%
706	Neuralgia	2.5%
707	Oroantral Fistula	2.5%
708	Paraplegia	2.5%
709	Pseudobulbar Palsy	2.5%
710	Quadriplegia	2.5%
711	Spasm	2.5%
712	Spastic Paraplegia	2.5%
713	Status Epilepticus	2.5%
714	Taste Disorders	2.5%
715	Tremor	2.5%
716	Monoplegia	2.5%
717	Hypokinesia	2.5%
718	Gastroparesis	2.5%
719	Paraparesis	2.5%
720	Bradykinesia	2.5%
721	Waxy flexibility	2.5%
722	Action Tremor	2.5%
723	Resting Tremor	2.5%
724	Dysosmia	2.5%
725	Quadriparesis	2.5%
726	Olfaction Disorders	2.5%
727	Myokymia	2.5%
728	Somatosensory Disorders	2.5%
729	Single umbilical artery	2.5%
730	Neuropathic pain	2.5%
731	Hyperkinesia	2.5%
732	Intention tremor	2.5%
733	Chagas Cardiomyopathy	2.4%
734	Rectal Prolapse	2.4%
735	Uterine Prolapse	2.4%
736	Vaginal Prolapse	2.4%
737	Gait Apraxia	2.4%
738	Cachexia	2.4%
739	Weight Gain	2.4%
740	Subacute Bacterial Endocarditis	2.3%
741	Voice Disorders	2.3%
742	Voice Disturbance	2.3%
743	Marfan Syndrome	2.2%
744	Gagging	2.2%
745	Leukoplakia, Oral	2.2%
746	Aortic Valve Prolapse	2.2%
747	Tricuspid Valve Prolapse	2.2%
748	Takotsubo Cardiomyopathy	2.2%
749	Umbilical hernia	2.1%
750	Toothache	2.1%
751	Alexia	2.1%
752	Dyslexia	2.1%
753	Vision Disorders	2.1%
754	Metamorphopsia	2.1%
755	Visual Impairment	2.1%
756	Hyperemesis Gravidarum	2%
757	Bronchial Fistula	2%
758	Metatarsalgia	2%
759	Pancreatic Fistula	2%
760	Dysgeusia	2%
761	Formication	2%
762	Hyperalgesia	2%
763	Hyperesthesia	2%
764	Hypesthesia	2%
765	Language Disorders	2%
766	Numbness	2%
767	Paresthesia	2%
768	Paraparesis, Spastic	2%
769	Trismus	2%
770	Epilepsia Partialis Continua	2%
771	Hypogeusia	2%
772	Brown-Sequard Syndrome	2%
773	Lockjaw	2%
774	Allodynia	2%
775	Ageusia	2%
776	Alice in Wonderland Syndrome	2%
777	Anisocoria	2%
778	Confusion	2%
779	Facial paralysis	2%
780	Intestinal Fistula	2%
781	Lethargy	2%
782	Memory Disorders	2%
783	Muscle Cramp	2%
784	Perceptual Disorders	2%
785	Psychomotor Disorders	2%
786	Tonic Pupil	2%
787	Anhedonia	2%
788	Disorientation	2%
789	Gastroschisis	2%
790	Enterocutaneous Fistula	2%
791	Fetal Hypoxia	2%
792	Facial Paresis	2%
793	Memory Loss	2%
794	Hemisensory Neglect	2%
795	Dysacusis	2%
796	Mastodynia	2%
797	Respiratory Paralysis	2%
798	Salivary Gland Fistula	2%
799	Chorea	2%
800	Cystocele	2%
801	Tetany	2%
802	Urinary Incontinence	2%
803	Breakthrough Pain	2%
804	Albuminuria	1.9%
805	Hemoglobinuria	1.9%
806	Truncus Arteriosus, Persistent	1.9%
807	Jet Lag Syndrome	1.9%
808	Reflex, Abnormal	1.9%
809	Hyporeflexia	1.9%
810	Hyperreflexia	1.9%
811	Birth Weight	1.8%
812	Agraphia	1.8%
813	Anomia	1.8%
814	Cluttering	1.8%
815	Language Development Disorders	1.8%
816	Speech Disorders	1.8%
817	Syncope	1.8%
818	Stupor	1.8%
819	Dysgraphia	1.8%
820	Presyncope	1.8%
821	Dyslalia	1.8%
822	MELAS Syndrome	1.8%
823	Aphasia	1.7%
824	Articulation Disorders	1.7%
825	Echolalia	1.7%
826	Stuttering	1.7%
827	Dysphasia	1.7%
828	Consciousness Disorders	1.7%
829	Mental Retardation	1.7%
830	Depressed Level of Consciousness	1.7%
831	Mental deficiency	1.7%
832	Intellectual Disability	1.7%
833	Catatonia	1.7%
834	Musculoskeletal Pain	1.7%
835	Ophthalmoplegia	1.7%
836	External Ophthalmoplegia	1.7%
837	Dural Arteriovenous Fistula	1.7%
838	Dysarthria	1.7%
839	Diplopia	1.7%
840	Muscle Rigidity	1.7%
841	Muscle Spasticity	1.7%
842	Scotoma	1.7%
843	Photophobia	1.7%
844	Cogwheel Rigidity	1.7%
845	Hemifacial Spasm	1.7%
846	Amaurosis	1.7%
847	Blindness	1.7%
848	Nuchal Rigidity	1.7%
849	Aphonia	1.6%
850	Arthralgia	1.6%
851	Sleep Deprivation	1.6%
852	Polyarthralgia	1.6%
853	Dysphonia	1.6%
854	Cerebrospinal Fluid Otorrhea	1.6%
855	Cerebrospinal Fluid Rhinorrhea	1.6%
856	Agnosia	1.6%
857	Apraxias	1.6%
858	Hallucinations	1.6%
859	Hemianopsia	1.6%
860	Hyperacusis	1.6%
861	Tinnitus	1.6%
862	Visual Agnosia	1.6%
863	Anosognosia	1.6%
864	Wernicke-Korsakoff Syndrome	1.6%
865	Phonophobia	1.6%
866	Hearing Loss	1.6%
867	Cerebellar Ataxia	1.6%
868	Torticollis	1.6%
869	Obesity	1.6%
870	Sciatica	1.6%
871	Urge Incontinence	1.6%
872	Tardive Dyskinesia	1.6%
873	Brain Hemorrhage, Traumatic	1.6%
874	Hydrops Fetalis	1.5%
875	Amaurosis Fugax	1.5%
876	Blindness, Cortical	1.5%
877	Dyscalculia	1.5%
878	Deafness	1.4%
879	Hearing Loss, Sudden	1.4%
880	Gerstmann Syndrome	1.4%
881	Hearing Loss, Bilateral	1.4%
882	Hearing Loss, High-Frequency	1.4%
883	Hearing Loss, Mixed Conductive-Sensorineural	1.4%
884	Prosopagnosia	1.4%
885	Apraxia, Ideomotor	1.4%
886	Persistent Vegetative State	1.4%
887	Charles Bonnet Syndrome	1.4%
888	Hearing Loss, Unilateral	1.4%
889	Complete Hearing Loss	1.4%
890	Alien Hand Syndrome	1.4%
891	Deaf Mutism	1.4%
892	Fetal Weight	1.4%
893	Vocal Cord Paralysis	1.4%
894	Kearns-Sayre syndrome	1.4%
895	Urinary Bladder Fistula	1.4%
896	Mutism	1.4%
897	Selective Mutism	1.4%
898	Tinea Pedis	1.4%
899	Amblyopia	1.4%
900	Amnesia	1.4%
901	Delirium	1.4%
902	Horner Syndrome	1.4%
903	Dissociative Amnesia	1.4%
904	Color blindness	1.4%
905	Global Amnesia	1.4%
906	Fabry Disease	1.4%
907	Rectal Fistula	1.4%
908	Anal Fistula	1.4%
909	Shoulder Pain	1.3%
910	Pediatric Obesity	1.3%
911	Alexia, Pure	1.3%
912	Turner Syndrome	1.3%
913	Dyskinesia, Drug-Induced	1.3%
914	Alcohol Withdrawal Seizures	1.2%
915	Retrograde amnesia	1.2%
916	Amnesia, Anterograde	1.2%
917	Akathisia, Drug-Induced	1.2%
918	Myalgia	1.2%
919	Kidney Calculi	1.1%
920	Ureteral Calculi	1.1%
921	Amnesia, Transient Global	1%
922	Auditory Perceptual Disorders	1%
923	Kartagener Syndrome	1%
924	Ophthalmoplegic Migraine	0.9%
925	Progressive supranuclear palsy	0.9%
926	Williams Syndrome	0.8%

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