MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cerebral Arteriosclerosis

(UMLS:C0877854)

UMLS ID:: C0877854
MeSH ID:: D002537

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.510.800

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.137.126.372|C14.907.253.560.350

Synonym(s)

Cerebral Arteriosclerosis

CEREBROVASCULAR ARTERIOSCLEROSIS

Cerebral arteriosclerosis

Cerebral vascular arteriosclerosis

arteriosclerosis; cerebral

arteriosclerosis; cerebrovascular

cerebral; arteriosclerosis

cerebrovascular; arteriosclerosis

cerebrovascular; disorder, arteriosclerotic

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 11	US FAERS
2	rofecoxib	FAERS: 9	OFFSIDES US FAERS
3	Rivaroxaban	FAERS: 4	US FAERS
4	Rosiglitazone	FAERS: 4	US FAERS
5	Carbamazepine	FAERS: 2	US FAERS
6	Celecoxib	FAERS: 2	OFFSIDES US FAERS
7	aliskiren	FAERS: 2	US FAERS
8	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
9	Anastrozole	FAERS: 1	US FAERS
10	Baclofen	FAERS: 1	US FAERS
11	Capecitabine	FAERS: 1	US FAERS
12	Cinacalcet	FAERS: 1	US FAERS
13	Donepezil	FAERS: 1	US FAERS
14	Droxidopa	FAERS: 1	US FAERS
15	Ezetimibe, Simvastatin Drug Combination	FAERS: 1	US FAERS
16	Felodipine	FAERS: 1	US FAERS
17	Fingolimod Hydrochloride	FAERS: 1	US FAERS
18	Fluoxetine	FAERS: 1	US FAERS
19	Glyburide	FAERS: 1	US FAERS
20	MDV 3100	FAERS: 1	US FAERS
21	Naproxen	FAERS: 1	US FAERS
22	Nicardipine	FAERS: 1	US FAERS
23	Risperidone	FAERS: 1	US FAERS
24	Sertraline	FAERS: 1	US FAERS
25	Sitagliptin Phosphate	FAERS: 1	US FAERS
26	Tiotropium Bromide	FAERS: 1	US FAERS
27	Tramadol	FAERS: 1	US FAERS
28	Valsartan	FAERS: 1	US FAERS
29	Varenicline	FAERS: 1	US FAERS
30	carbidopa, levodopa drug combination	FAERS: 1	US FAERS
31	paricalcitol	FAERS: 1	US FAERS
32	ponatinib	FAERS: 1	US FAERS
33	testosterone 17 beta-cypionate	FAERS: 1	US FAERS
34	Acetaminophen		OFFSIDES
35	Ampicillin		OFFSIDES
36	Aripiprazole		OFFSIDES
37	Aspirin		OFFSIDES
38	Atenolol		OFFSIDES
39	Beclomethasone		OFFSIDES
40	Beclomethasone		OFFSIDES
41	Bisacodyl		OFFSIDES
42	Brimonidine Tartrate		OFFSIDES
43	Carboplatin		OFFSIDES
44	Cefadroxil		OFFSIDES
45	Chlorhexidine		OFFSIDES
46	Chloroquine		OFFSIDES
47	Desvenlafaxine Succinate		OFFSIDES
48	Diazepam		OFFSIDES
49	Docetaxel		OFFSIDES
50	Doxepin		OFFSIDES
51	Dronabinol		OFFSIDES
52	Ephedrine		OFFSIDES
53	Eptifibatide		OFFSIDES
54	Estrogens, Conjugated (USP)		OFFSIDES
55	Fentanyl		OFFSIDES
56	Formoterol Fumarate		OFFSIDES
57	Fosinopril		OFFSIDES
58	Fulvestrant		OFFSIDES
59	Furosemide		OFFSIDES
60	Ifosfamide		SIDER
61	Lenalidomide		OFFSIDES
62	Letrozole		OFFSIDES
63	Lisinopril		OFFSIDES
64	Lovastatin		OFFSIDES
65	Metformin		OFFSIDES
66	Mometasone Furoate		OFFSIDES
67	Nabumetone		OFFSIDES
68	Nalidixic Acid		SIDER
69	Nortriptyline		OFFSIDES
70	Oxaprozin		OFFSIDES
71	Pamidronate		OFFSIDES
72	Paroxetine		OFFSIDES
73	Pyridostigmine Bromide		OFFSIDES
74	Quinidine		OFFSIDES
75	Rosuvastatin Calcium		OFFSIDES
76	Rosuvastatin Calcium		OFFSIDES
77	Salmeterol Xinafoate		OFFSIDES
78	Simethicone		OFFSIDES
79	Tadalafil		OFFSIDES
80	Tamoxifen		OFFSIDES
81	Topiramate		OFFSIDES
82	Travoprost		OFFSIDES
83	Vinorelbine		OFFSIDES
84	Vitamin E		OFFSIDES
85	Zinc Sulfate		OFFSIDES
86	Zoledronic Acid		OFFSIDES
87	acetaminophen, dextropropoxyphene, drug combination		OFFSIDES
88	argatroban		OFFSIDES
89	benazepril		OFFSIDES
90	candesartan cilexetil		OFFSIDES
91	chlorhexidine gluconate		OFFSIDES
92	dolasetron		OFFSIDES
93	exemestane		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Moyamoya Disease	46.2%
2	Intracranial Aneurysm	45.7%
3	Cerebral Arterial Diseases	42.9%
4	Carotid Stenosis	34.9%
5	Intracranial Embolism and Thrombosis	34.8%
6	Carotid Artery Diseases	34%
7	Brain Ischemia	34%
8	Cerebrovascular accident	34%
9	Vasospasm, Intracranial	34%
10	Basal Ganglia Cerebrovascular Disease	34%
11	Infarction, Middle Cerebral Artery	33.1%
12	Infarction, Anterior Cerebral Artery	33.1%
13	Infarction, Posterior Cerebral Artery	33.1%
14	Brain Infarction	32%
15	Vascular Headaches	32%
16	Leriche Syndrome	31.3%
17	Thromboangiitis Obliterans	31.3%
18	Vasculitis, Central Nervous System	30.9%
19	Carotid Artery Thrombosis	29.3%
20	Leukomalacia, Periventricular	29.2%
21	Arteriosclerosis Obliterans	28.9%
22	Atherosclerosis	28.9%
23	Coronary Artery Disease	27.9%
24	Cerebral Amyloid Angiopathy	26.8%
25	Myocardial Ischemia	26.8%
26	Malignant Atrophic Papulosis	26.2%
27	Carotid Artery Injuries	26%
28	Spinal Cord Vascular Diseases	24.8%
29	Aneurysm	24.7%
30	Angiomatosis	24.7%
31	Aortic Diseases	24.7%
32	Hyperemia	24.7%
33	Hypotension	24.7%
34	Superior Vena Cava Syndrome	24.7%
35	Telangiectasis	24.7%
36	Vasculitis	24.7%
37	Venous Insufficiency	24.7%
38	Peripheral Vascular Diseases	24.7%
39	Embolism and Thrombosis	24.7%
40	Angiodysplasia	24.7%
41	Capillary Leak Syndrome	24.7%
42	Prehypertension	24.7%
43	Hypoxia-Ischemia, Brain	24.3%
44	Fibromuscular Dysplasia	24.3%
45	Pulmonary artery stenosis	24.3%
46	Basal Ganglia Hemorrhage	24.2%
47	Cerebral Infarction	23.9%
48	Brain Stem Infarctions	23.9%
49	Subarachnoid Hemorrhage, Traumatic	23.6%
50	Intermittent Claudication	23.6%
51	Cerebral Thrombosis	23.5%
52	Intracranial Embolism	23.5%
53	Intracranial Thrombosis	23.5%
54	Aortic Aneurysm	23.5%
55	Aortitis	23.5%
56	Periphlebitis	23.5%
57	Phlebitis	23.5%
58	Vertebrobasilar Insufficiency	22.4%
59	Basilar Artery Stenosis	22.4%
60	Vertebral Artery Stenosis	22.4%
61	Intracranial Hemorrhage, Hypertensive	22.4%
62	Transient Cerebral Ischemia	22.4%
63	Retinal Vein Occlusion	21.5%
64	Carotid Artery, Internal, Dissection	21.1%
65	Thoracic Outlet Syndrome	20.7%
66	Vascular System Injuries	20.6%
67	Compartment syndromes	20.1%
68	Hepatic Veno-Occlusive Disease	20.1%
69	Peliosis Hepatis	20.1%
70	Varicocele	20.1%
71	Vertebral Artery Dissection	20%
72	Giant Cell Arteritis	19.9%
73	Temporal Arteritis	19.9%
74	Lateral Medullary Syndrome	19.8%
75	Diabetic Angiopathies	19.8%
76	Reperfusion Injury	19.8%
77	Retinal Artery Occlusion	19.8%
78	Splenic Infarction	19.8%
79	Vascular Neoplasms	19.8%
80	Vasoplegia	19.8%
81	Hemorrhoids	19.7%
82	Myocardial Reperfusion Injury	19.6%
83	Shwartzman Phenomenon	19.5%
84	Pituitary Apoplexy	19.5%
85	Postphlebitic Syndrome	19.4%
86	Putaminal Hemorrhage	18.8%
87	Subarachnoid Hemorrhage	18.7%
88	Cerebral Hemorrhage	18.7%
89	Hand-Arm Vibration Syndrome	18.5%
90	Coronary Aneurysm	18.3%
91	Optic Neuropathy, Ischemic	18.1%
92	Anterior Ischemic Optic Neuropathy	18.1%
93	Sinus Thrombosis, Intracranial	17.9%
94	Thrombophlebitis	17.6%
95	Dementia, Vascular	16.9%
96	Aortic Rupture	16.8%
97	Subclavian Steal Syndrome	16.7%
98	Mesenteric vascular insufficiency	16.7%
99	Mesenteric Vascular Occlusion	16.5%
100	Blue Toe Syndrome	16.4%
101	Angioedema	16.3%
102	Colitis, Ischemic	16.3%
103	Renal Artery Obstruction	16.3%
104	Renal Artery Stenosis	16.3%
105	Arteriovenous fistula	15.8%
106	Lupus Vasculitis, Central Nervous System	15.8%
107	Coronary heart disease	15.6%
108	Myocardial Infarction	15.6%
109	Acute Coronary Syndrome	15.6%
110	Aortic Aneurysm, Abdominal	15.4%
111	Aortic Aneurysm, Thoracic	15.4%
112	Heart Diseases	15.3%
113	Cavernous Sinus Thrombosis	15.1%
114	Sagittal Sinus Thrombosis	15.1%
115	Coronary Thrombosis	15%
116	Aneurysm, Dissecting	14.6%
117	Arteritis	14.6%
118	Embolism	14.6%
119	Erythromelalgia	14.6%
120	Malignant Hypertension	14.6%
121	Raynaud Disease	14.6%
122	Thromboembolism	14.6%
123	Thrombosis	14.6%
124	Essential Hypertension	14.6%
125	Aneurysm, Ruptured	14.6%
126	Iliac Aneurysm	14.6%
127	White Coat Hypertension	14.6%
128	Systemic Vasculitis	14.6%
129	Embolus	14.6%
130	Spinal Cord Ischemia	14.6%
131	Subdural Effusion	14.2%
132	Akinetic Mutism	14.2%
133	Anoxic Encephalopathy	14.2%
134	Basal Ganglia Diseases	14.2%
135	Brain Damage, Chronic	14.2%
136	Cerebellar Diseases	14.2%
137	Encephalitis	14.2%
138	Encephalomalacia	14.2%
139	Epilepsy	14.2%
140	Hydrocephalus	14.2%
141	Congenital Hydrocephalus	14.2%
142	Hypothalamic Diseases	14.2%
143	Thalamic Diseases	14.2%
144	Intracranial Hypertension	14.2%
145	Aura	14.2%
146	Leukoencephalopathy	14.2%
147	Neuroaxonal Dystrophies	14.2%
148	Headache Disorders	14.2%
149	Intracranial Hypotension	14.2%
150	Brain Edema	14.2%
151	Brain Hypoxia	14.2%
152	Aqueductal Stenosis	14.2%
153	Meningoencephalitis	13.9%
154	Encephalomyelitis	13.9%
155	Shy-Drager Syndrome	13.6%
156	Scimitar Syndrome	13.4%
157	Kounis Syndrome	13.2%
158	May-Thurner Syndrome	13%
159	Angina Pectoris	13%
160	Polyarteritis Nodosa	12.9%
161	Takayasu Arteritis	12.9%
162	Brain Hemorrhage, Traumatic	12.8%
163	Hypotension, Orthostatic	12.6%
164	Post-Exercise Hypotension	12.6%
165	Pregnancy Complications, Cardiovascular	12.4%
166	Cardiovascular Abnormalities	12.4%
167	Arterial Occlusive Diseases	12.3%
168	Sturge-Weber Syndrome	12.3%
169	Embolism, Amniotic Fluid	12.1%
170	Dandy-Walker Syndrome	11.9%
171	Pneumocephalus	11.9%
172	Retinal Vasculitis	11.9%
173	Hypertensive Retinopathy	11.9%
174	Brain Abscess	11.8%
175	Multiple System Atrophy	11.8%
176	Anterior Compartment Syndrome	11.7%
177	Vasculitis, Leukocytoclastic, Cutaneous	11.7%
178	Gastric Antral Vascular Ectasia	11.7%
179	Abdominal Compartment Syndrome	11.7%
180	Varicose Ulcer	11.7%
181	Parkinsonian Disorders	11.7%
182	Primary Graft Dysfunction	11.7%
183	Brain Diseases, Metabolic	11.6%
184	Dementia	11.6%
185	MELAS Syndrome	11.5%
186	Posterior Leukoencephalopathy Syndrome	11.2%
187	Posterior reversible encephalopathy syndrome	11.2%
188	Meningitis	11.1%
189	Movement Disorders	11.1%
190	Pachymeningitis	11.1%
191	Spinal Cord Diseases	11.1%
192	Brain Injuries	10.9%
193	Brain Neoplasms	10.8%
194	Lewy Body Disease	10.8%
195	CREST Syndrome	10.8%
196	Ocular Motility Disorders	10.4%
197	Cyclophoria	10.4%
198	Epilepsy, Post-Traumatic	10.3%
199	Coronary Occlusion	10.3%
200	Microvascular Angina	10.3%
201	Coronary Stenosis	10.3%
202	ST segment elevation myocardial infarction	10.3%
203	Mucocutaneous Lymph Node Syndrome	9.9%
204	Cerebrovascular Disorders	9.9%
205	Cerebrovascular Insufficiency	9.9%
206	Hematoma, Subdural	9.9%
207	Hematoma, Epidural, Cranial	9.9%
208	Diabetic Retinopathy	9.9%
209	Brain Death	9.9%
210	Marchiafava-Bignami Disease	9.8%
211	Livedo Reticularis	9.8%
212	Myelitis	9.8%
213	Renal hypertension	9.8%
214	Hemangioma, Cavernous	9.7%
215	Scurvy	9.7%
216	Meige Syndrome	9.6%
217	Cerebral Ventriculitis	9.6%
218	Air Embolism	9.6%
219	Endarteritis	9.6%
220	Venous Thrombosis	9.6%
221	Deep Vein Thrombosis	9.6%
222	Venous Thromboembolism	9.6%
223	Anterior Spinal Artery Syndrome	9.6%
224	Ataxia Telangiectasia	9.5%
225	Central Nervous System Infection	9.3%
226	Lemierre Syndrome	9.2%
227	Epidural Abscess	9%
228	Myoclonic Epilepsy	8.9%
229	Epilepsy, Temporal Lobe	8.9%
230	Epilepsy, Rolandic	8.9%
231	Benign Rolandic Epilepsy	8.9%
232	Amblyopia	8.9%
233	Parkinson Disease	8.7%
234	Huntington Disease	8.6%
235	Shock, Cardiogenic	8.6%
236	Angina, Unstable	8.5%
237	Cerebellar Neoplasms	8.4%
238	Cerebral Palsy	8.4%
239	Epilepsies, Partial	8.4%
240	Epilepsy, Generalized	8.4%
241	Pseudotumor Cerebri	8.4%
242	Hypertensive Encephalopathy	8.4%
243	Simple Partial Seizures	8.4%
244	Epilepsy, Reflex	8.4%
245	Headache Disorders, Primary	8.4%
246	Headache Disorders, Secondary	8.4%
247	Medication overuse headache	8.4%
248	Ischemic contracture	8.4%
249	Angioedemas, Hereditary	8.4%
250	Tricuspid Atresia	8.4%
251	Arrhythmogenic Right Ventricular Dysplasia	8.4%
252	Cryoglobulinemia	8.4%
253	Fabry Disease	8.3%
254	Diabetic Foot	8.3%
255	Cardiac Tamponade	8.2%
256	Endocarditis	8.2%
257	Cardiac Arrest	8.2%
258	Heart failure	8.2%
259	Pericardial effusion	8.2%
260	Pericarditis	8.2%
261	Pneumopericardium	8.2%
262	Cor pulmonale	8.2%
263	Ventricular Outflow Obstruction	8.2%
264	Ventricular Dysfunction	8.2%
265	Cardiomyopathies	8.2%
266	Pleuropericarditis	8.2%
267	Neuroleptic Malignant Syndrome	8.2%
268	Myelinolysis, Central Pontine	8.2%
269	Dystonia Musculorum Deformans	8.1%
270	Creutzfeldt-Jakob disease	8.1%
271	Hematoma, Subdural, Intracranial	8.1%
272	Hematoma, Subdural, Chronic	8.1%
273	Hematoma, Subdural, Acute	8.1%
274	Prion Diseases	7.9%
275	Stiff-Person Syndrome	7.9%
276	Pulmonary Embolism	7.9%
277	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.9%
278	Aortic Valve Stenosis	7.8%
279	Cardiomyopathy, Dilated	7.8%
280	Pulmonary Valve Stenosis	7.8%
281	No-Reflow Phenomenon	7.8%
282	Coronary Restenosis	7.7%
283	Bacterial Endocarditis	7.6%
284	Progressive supranuclear palsy	7.6%
285	Amnesia, Transient Global	7.5%
286	Arteriosclerosis	7.3%
287	Purpura, Hyperglobulinemic	7.3%
288	Cranial nerve diseases	7.2%
289	Demyelinating Diseases	7.2%
290	Demyelination	7.2%
291	Neuromuscular Diseases	7.2%
292	Chronobiology Disorders	7.2%
293	Leukoencephalopathy, Progressive Multifocal	7.2%
294	Striatonigral Degeneration	7.1%
295	Limbic Encephalitis	7.1%
296	Pituitary Diseases	7.1%
297	Presenile dementia	7%
298	Senile dementia	7%
299	Spinal Cord Injuries	6.8%
300	Subacute Combined Degeneration	6.8%
301	Spinal Muscular Atrophy	6.8%
302	Progressive Muscular Atrophy	6.8%
303	Kluver-Bucy Syndrome	6.8%
304	Cardiac Output, High	6.7%
305	Myocardial Stunning	6.7%
306	Low Cardiac Output Syndrome	6.7%
307	Juvenile Myoclonic Epilepsy	6.7%
308	Myoclonic Epilepsies, Progressive	6.7%
309	Asterixis	6.6%
310	Ballismus	6.6%
311	Cardiomegaly	6.6%
312	Postpericardiotomy Syndrome	6.6%
313	Cardiac Hypertrophy	6.6%
314	Behcet Syndrome	6.6%
315	Heart Block	6.5%
316	Tachycardia	6.5%
317	Tachyarrhythmia	6.5%
318	Rheumatic Heart Disease	6.5%
319	Waldenstrom Macroglobulinemia	6.5%
320	Multiple Myeloma	6.5%
321	Aortic coarctation	6.5%
322	Cor Triatriatum	6.5%
323	Coronary Vessel Anomalies	6.5%
324	Patent ductus arteriosus	6.5%
325	Ebstein Anomaly	6.5%
326	Heart Septal Defects	6.5%
327	Tetralogy of Fallot	6.5%
328	Transposition of Great Vessels	6.5%
329	Meningitis, Bacterial	6.5%
330	Meningitis, Fungal	6.5%
331	Hypoplastic Left Heart Syndrome	6.5%
332	Brain Injuries, Diffuse	6.4%
333	Traumatic Brain Injury	6.4%
334	Cerebellar Ataxia	6.4%
335	Intracranial Arteriosclerosis	6.4%
336	Cerebral Atherosclerosis	6.4%
337	Hypertension, Renovascular	6.4%
338	Supratentorial Neoplasms	6.4%
339	Cerebral Arteriosclerosis	6.4%
340	Hepatolenticular Degeneration	6.4%
341	Hereditary Angioedema Type III	6.4%
342	Hereditary Angioedema Types I and II	6.4%
343	Angina Pectoris, Variant	6.4%
344	Poliomyelitis	6.3%
345	Amyotrophic Lateral Sclerosis	6.1%
346	Persistent Vegetative State	6.1%
347	Arachnoiditis	6.1%
348	Aseptic Meningitis	6.1%
349	Syringomyelia	6.1%
350	Essential Tremor	6.1%
351	Familial Tremor	6.1%
352	Pneumorrhachis	6.1%
353	Writer's Cramp	6.1%
354	Paraneoplastic Cerebellar Degeneration	6%
355	Motor Neuron Disease	6%
356	Trauma, Nervous System	6%
357	Pseudoxanthoma Elasticum	6%
358	MPTP Poisoning	5.9%
359	Leukoencephalitis, Acute Hemorrhagic	5.9%
360	Pituitary Adenoma	5.9%
361	Pituitary Neoplasms	5.9%
362	Chronic Fatigue Syndrome	5.9%
363	Hepatic Vein Thrombosis	5.9%
364	Budd-Chiari Syndrome	5.9%
365	Nervous System Neoplasms	5.8%
366	Neurologic Manifestations	5.8%
367	Neurotoxicity Syndromes	5.8%
368	Intracranial Arterial Diseases	5.8%
369	Toxoplasmosis, Cerebral	5.8%
370	Hypertrophic Cardiomyopathy	5.8%
371	Pulmonary Infarction	5.8%
372	Hypertrophic obstructive cardiomyopathy	5.8%
373	Reye Syndrome	5.7%
374	Hepatic Encephalopathy	5.7%
375	Ophthalmoplegic Migraine	5.7%
376	Post-Traumatic Headache	5.6%
377	Tension Headache	5.6%
378	Epilepsy, Complex Partial	5.6%
379	Migraine Disorders	5.6%
380	Abdominal Migraine	5.6%
381	Status Migrainosus	5.6%
382	Cervicogenic Headache	5.6%
383	Dextrocardia	5.6%
384	Long QT Syndrome	5.6%
385	Encephalomyelitis, Acute Disseminated	5.6%
386	Spinal Cord Neoplasms	5.4%
387	Miller Fisher Syndrome	5.4%
388	Friedreich Ataxia	5.2%
389	Restless Legs Syndrome	5.2%
390	Lafora Disease	5.2%
391	Unverricht-Lundborg Syndrome	5.2%
392	Supravalvular aortic stenosis	5.1%
393	Lown-Ganong-Levine Syndrome	5.1%
394	Canavan Disease	5.1%
395	Alexander Disease	5.1%
396	Polyradiculoneuropathy	5%
397	Polyradiculoneuritis	5%
398	Akathisia, Drug-Induced	5%
399	Sleep Wake Disorders	5%
400	Central Nervous System Fungal Infections	5%
401	Conus Medullaris Syndrome	5%
402	Dural Arteriovenous Fistula	4.9%
403	Brain Diseases, Metabolic, Inborn	4.9%
404	Myelitis, Transverse	4.9%
405	Mitochondrial Encephalomyopathies	4.9%
406	Rheumatoid Vasculitis	4.9%
407	Granulomatosis with polyangiitis	4.9%
408	Aortic Valve Insufficiency	4.9%
409	Restrictive cardiomyopathy	4.9%
410	Endocardial Fibroelastosis	4.9%
411	Heart Rupture, Post-Infarction	4.9%
412	Mitral Valve Insufficiency	4.9%
413	Mitral Valve Stenosis	4.9%
414	Myocarditis	4.9%
415	Pericarditis, Constrictive	4.9%
416	Pulmonary Valve Insufficiency	4.9%
417	Tricuspid Valve Insufficiency	4.9%
418	Tricuspid Valve Stenosis	4.9%
419	Ventricular Dysfunction, Left	4.9%
420	Right Ventricular Dysfunction	4.9%
421	Endomyocardial Fibrosis	4.9%
422	Carditis	4.9%
423	Heart Failure, Systolic	4.9%
424	Heart Failure, Diastolic	4.9%
425	Sick Sinus Syndrome	4.8%
426	Autonomic Dysreflexia	4.6%
427	Complex Regional Pain Syndromes	4.6%
428	Opsoclonus-Myoclonus Syndrome	4.6%
429	Carcinoid Heart Disease	4.6%
430	Empty Sella Syndrome	4.6%
431	Hyperpituitarism	4.6%
432	Hypopituitarism	4.6%
433	Hypophysitis	4.6%
434	Noonan Syndrome	4.4%
435	Auditory Perceptual Disorders	4.3%
436	Adams-Stokes Syndrome	4.3%
437	Atrioventricular Block	4.3%
438	Bundle-Branch Block	4.3%
439	Atrial Premature Complexes	4.3%
440	Sinoatrial Block	4.3%
441	Tachycardia, Paroxysmal	4.3%
442	Supraventricular tachycardia	4.3%
443	Tachycardia, Ventricular	4.3%
444	Wolff-Parkinson-White Syndrome	4.3%
445	Tachycardia, Reciprocating	4.3%
446	Aortopulmonary Septal Defect	4.3%
447	Double Outlet Right Ventricle	4.3%
448	Endocardial Cushion Defects	4.3%
449	Myocardial bridging	4.3%
450	Aorticopulmonary Septal Defect	4.3%
451	Wernicke Encephalopathy	4.3%
452	Diffuse Axonal Injury	4.3%
453	AIDS Dementia Complex	4.3%
454	Brain Stem Neoplasms	4.2%
455	Dyskinesia, Drug-Induced	4.2%
456	Tuberculosis, Meningeal	4.2%
457	Cluster Headache	4.2%
458	Migraine with Aura	4.2%
459	Familial Hemiplegic Migraine	4.2%
460	Chronic Paroxysmal Hemicrania	4.2%
461	SUNCT Syndrome	4.2%
462	Paroxysmal Hemicrania	4.2%
463	Central Nervous System Bacterial Infections	4.2%
464	Subacute Bacterial Endocarditis	4.1%
465	Marfan Syndrome	4%
466	Sinus Arrhythmia	3.9%
467	Atrial Fibrillation	3.9%
468	Atrial Flutter	3.9%
469	Edema, Cardiac	3.9%
470	Ventricular Fibrillation	3.9%
471	Ventricular Flutter	3.9%
472	Parasystole	3.9%
473	Paroxysmal atrial fibrillation	3.9%
474	Bradycardia	3.9%
475	Diabetic Cardiomyopathies	3.9%
476	Peripheral Nerve Injuries	3.9%
477	Frontotemporal dementia	3.9%
478	Cardiomyopathy, Alcoholic	3.9%
479	Ectopia Cordis	3.9%
480	Sudden Cardiac Death	3.9%
481	Left Ventricular Hypertrophy	3.9%
482	Right Ventricular Hypertrophy	3.9%
483	Single umbilical artery	3.9%
484	Chagas Cardiomyopathy	3.9%
485	Myasthenia Gravis	3.9%
486	Kernicterus	3.9%
487	Adrenoleukodystrophy	3.8%
488	Scrapie	3.8%
489	Central Cord Syndrome	3.8%
490	Chorea	3.8%
491	Dysautonomia	3.7%
492	Vagus Nerve Disorder	3.7%
493	Glossopharyngeal Neuralgia	3.7%
494	Abducens Nerve Diseases	3.7%
495	Heavy Metal Poisoning, Nervous System	3.7%
496	Neuromuscular Junction Diseases	3.7%
497	Tauopathies	3.7%
498	Trochlear Nerve Diseases	3.7%
499	Peripheral Nervous System Diseases	3.7%
500	Subacute Sclerosing Panencephalitis	3.7%
501	Romano-Ward Syndrome	3.7%
502	Brain Contusion	3.7%
503	Lambert-Eaton Myasthenic Syndrome	3.5%
504	Meningitis, Cryptococcal	3.5%
505	Guillain-Barre Syndrome	3.5%
506	Meningitis, Listeria	3.4%
507	Meningitis, Haemophilus	3.4%
508	Meningitis, Pneumococcal	3.4%
509	Sleep Disorders, Circadian Rhythm	3.4%
510	Brain Concussion	3.4%
511	Hyperprolactinemia	3.4%
512	Pick Disease of the Brain	3.3%
513	Botulism	3.3%
514	Central Nervous System Cysts	3.3%
515	Progressive bulbar palsy	3.3%
516	Bulbar palsy	3.3%
517	Dyspnea, Paroxysmal	3.3%
518	Aortic Valve Prolapse	3.2%
519	Tricuspid Valve Prolapse	3.2%
520	Takotsubo Cardiomyopathy	3.2%
521	Torticollis	3.2%
522	Tachycardia, Atrioventricular Nodal Reentry	3.2%
523	Tachycardia, Ectopic Atrial	3.2%
524	Tachycardia, Ectopic Junctional	3.2%
525	Sinus Tachycardia	3.2%
526	Torsades de Pointes	3.2%
527	Accelerated Idioventricular Rhythm	3.2%
528	Truncus Arteriosus, Persistent	3.2%
529	Choroid Plexus Papilloma	3.2%
530	Myopathy	3.1%
531	Optic Neuropathy	3.1%
532	Olfactory Nerve Injuries	3%
533	Facial Nerve Diseases	3%
534	Craniocerebral Trauma	3%
535	Parasomnia	3%
536	Dyssomnias	3%
537	Vestibulocochlear Nerve Diseases	3%
538	Decerebrate State	3%
539	Hemiparesis	3%
540	Hydranencephaly	3%
541	Meningism	3%
542	Neural Tube Defects	3%
543	Paresis	3%
544	Seizures	3%
545	Sensation Disorders	3%
546	Tethered Cord Syndrome	3%
547	Central Nervous System Neoplasms	3%
548	Complex partial seizures	3%
549	Iniencephaly	3%
550	Craniorachischisis	3%
551	Exencephaly	3%
552	Monoparesis	3%
553	Septo-Optic Dysplasia	3%
554	Cortical Dysplasia	3%
555	Neurogenic Inflammation	3%
556	Gait Disorders, Neurologic	3%
557	Neuromuscular Manifestations	3%
558	Malformations of Cortical Development	3%
559	Causalgia	3%
560	Sweating, Gustatory	3%
561	Auriculotemporal Syndrome	3%
562	Alice in Wonderland Syndrome	2.9%
563	Tuberculosis, Central Nervous System	2.9%
564	Acromegaly	2.8%
565	Horner Syndrome	2.8%
566	Neuromyelitis Optica	2.8%
567	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.8%
568	Refsum Disease	2.8%
569	Multiple Sclerosis	2.7%
570	Facial Nerve Injuries	2.6%
571	West Nile Fever	2.6%
572	Reflex Sympathetic Dystrophy	2.6%
573	Nocturnal Myoclonus Syndrome	2.6%
574	Sinus Arrest, Cardiac	2.6%
575	Pupil Disorders	2.6%
576	Neurobehavioral Manifestations	2.6%
577	Paraneoplastic Encephalomyelitis	2.5%
578	Galactosemias	2.5%
579	Urea Cycle Disorders, Inborn	2.5%
580	Tyrosinemias	2.5%
581	Uveomeningoencephalitic Syndrome	2.5%
582	Vertigo	2.5%
583	Alcohol-Induced Disorders, Nervous System	2.5%
584	Jet Lag Syndrome	2.5%
585	Neuroaspergillosis	2.4%
586	Turner Syndrome	2.4%
587	Tardive Dyskinesia	2.4%
588	Tuberous Sclerosis	2.4%
589	Ophthalmoplegia	2.4%
590	External Ophthalmoplegia	2.4%
591	Myasthenia Gravis, Autoimmune, Experimental	2.3%
592	Homocystinuria	2.3%
593	Leigh Disease	2.3%
594	Kearns-Sayre syndrome	2.2%
595	Pseudorabies	2.2%
596	Voice Disorders	2.2%
597	Voice Disturbance	2.2%
598	Acrodynia	2.2%
599	Smith-Magenis syndrome	2.1%
600	Prolactinoma	2.1%
601	Growth Hormone-Secreting Pituitary Adenoma	2.1%
602	Williams Syndrome	2.1%
603	Vocal Cord Paralysis	2.1%
604	Neurosyphilis	2.1%
605	Neuritis	2%
606	Polyneuritis	2%
607	Radiculitis	2%
608	Polyneuropathy	2%
609	Mononeuritis	2%
610	Mononeuropathies	2%
611	Brachial Plexus Neuropathies	2%
612	Radiculopathy	2%
613	Mononeuropathy Multiplex	2%
614	Nerve Root Compression	2%
615	Charcot-Marie-Tooth Disease	2%
616	Nelson Syndrome	2%
617	Menkes Kinky Hair Syndrome	2%
618	Brachial Plexus Neuritis	1.9%
619	Neuralgic Amyotrophy	1.9%
620	Myotonia Congenita	1.9%
621	Cerebrospinal Fluid Otorrhea	1.8%
622	Cerebrospinal Fluid Rhinorrhea	1.8%
623	Neuritis, Autoimmune, Experimental	1.8%
624	Gait Ataxia	1.8%
625	Reflex, Abnormal	1.8%
626	Hyporeflexia	1.8%
627	Hyperreflexia	1.8%
628	Lyme Neuroborreliosis	1.8%
629	Alcohol Withdrawal Seizures	1.8%
630	Kartagener Syndrome	1.8%
631	Zellweger Syndrome	1.8%
632	Coma, Post-Head Injury	1.8%
633	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.7%
634	Myositis	1.7%
635	Optic Atrophy	1.7%
636	Optic Neuritis	1.7%
637	Papilledema	1.7%
638	Strabismus	1.7%
639	Tolosa-Hunt Syndrome	1.7%
640	Isaacs syndrome	1.7%
641	Arsenic Poisoning	1.7%
642	Myotonic Disorders	1.7%
643	Myasthenic Syndromes, Congenital	1.7%
644	Toxoplasmosis, Congenital	1.6%
645	Diabetic Neuropathies	1.6%
646	Facial Injuries	1.6%
647	Facial Neuralgia	1.6%
648	Myotonic Dystrophy	1.6%
649	Diabetic Amyotrophy	1.6%
650	Diabetic Autonomic Neuropathy	1.6%
651	Sleep Talking	1.6%
652	Manganese Poisoning	1.6%
653	Sleep Disorders, Intrinsic	1.6%
654	Orthostatic intolerance	1.6%
655	Malaria, Cerebral	1.6%
656	Akathisia	1.6%
657	Restlessness	1.6%
658	Psychomotor Agitation	1.6%
659	Anosmia	1.6%
660	Ataxia	1.6%
661	Athetosis	1.6%
662	Catalepsy	1.6%
663	Dystonia	1.6%
664	Hemiplegia	1.6%
665	Locked-In Syndrome	1.6%
666	Meningeal Neoplasms	1.6%
667	Meningomyelocele	1.6%
668	Muscle Hypertonia	1.6%
669	Muscle hypotonia	1.6%
670	Myoclonus	1.6%
671	Myotonia	1.6%
672	Neuralgia	1.6%
673	Paraplegia	1.6%
674	Pseudobulbar Palsy	1.6%
675	Quadriplegia	1.6%
676	Spasm	1.6%
677	Spastic Paraplegia	1.6%
678	Status Epilepticus	1.6%
679	Taste Disorders	1.6%
680	Tremor	1.6%
681	Spina Bifida	1.6%
682	Monoplegia	1.6%
683	Hypokinesia	1.6%
684	Paraparesis	1.6%
685	Bradykinesia	1.6%
686	Waxy flexibility	1.6%
687	Action Tremor	1.6%
688	Resting Tremor	1.6%
689	Dysosmia	1.6%
690	Quadriparesis	1.6%
691	Mercury Poisoning, Nervous System	1.6%
692	Olfaction Disorders	1.6%
693	Myokymia	1.6%
694	Lead Poisoning, Nervous System	1.6%
695	Vestibular Neuronitis	1.6%
696	Somatosensory Disorders	1.6%
697	Neuropathic pain	1.6%
698	Hyperkinesia	1.6%
699	Intention tremor	1.6%
700	Neurocysticercosis	1.6%
701	Multiple Sclerosis, Chronic Progressive	1.6%
702	Multiple Sclerosis, Relapsing-Remitting	1.6%
703	Tarsal Tunnel Syndrome	1.6%
704	Cauda Equina Syndrome	1.6%
705	Glycogen storage disease type II	1.5%
706	Waterhouse-Friderichsen Syndrome	1.4%
707	Gait Apraxia	1.4%
708	Vision Disorders	1.4%
709	Metamorphopsia	1.4%
710	Visual Impairment	1.4%
711	Fibromyalgia	1.4%
712	Medial Tibial Stress Syndrome	1.4%
713	Facial Hemiatrophy	1.4%
714	Melkersson-Rosenthal Syndrome	1.4%
715	Mitochondrial Myopathies	1.4%
716	Anisocoria	1.4%
717	Confusion	1.4%
718	Facial paralysis	1.4%
719	Lethargy	1.4%
720	Memory Disorders	1.4%
721	Muscle Cramp	1.4%
722	Perceptual Disorders	1.4%
723	Psychomotor Disorders	1.4%
724	Tonic Pupil	1.4%
725	Eosinophilia-Myalgia Syndrome	1.4%
726	Anhedonia	1.4%
727	Disorientation	1.4%
728	Facial Paresis	1.4%
729	Memory Loss	1.4%
730	Hemisensory Neglect	1.4%
731	Dysacusis	1.4%
732	Sleep Bruxism	1.4%
733	Anencephaly	1.4%
734	Meningocele	1.4%
735	Muscular Atrophy	1.4%
736	Respiratory Paralysis	1.4%
737	Encephalocele	1.4%
738	Optic Nerve Glioma	1.4%
739	Alstrom Syndrome	1.4%
740	Acoustic Neuroma	1.4%
741	Tetany	1.3%
742	Carpal Tunnel Syndrome	1.3%
743	neurofibroma	1.3%
744	Sciatica	1.3%
745	Amyloid Neuropathies, Familial	1.3%
746	Sciatic Neuropathy	1.2%
747	Ulnar Neuropathies	1.2%
748	Lesion of Sciatic Nerve	1.2%
749	Ulnar Neuritis	1.2%
750	Radial nerve compression	1.2%
751	Radial Tunnel Syndrome	1.2%
752	Peroneal Neuropathies	1.2%
753	Radial Neuropathy	1.2%
754	Median Neuropathy	1.2%
755	Sciatic Nerve Palsy	1.2%
756	Femoral Neuropathy	1.2%
757	Tibial Neuropathy	1.2%
758	Ulnar Nerve Palsy	1.2%
759	Postural Orthostatic Tachycardia Syndrome	1.2%
760	Radial nerve palsy	1.2%
761	Duane Retraction Syndrome	1.2%
762	Consciousness Disorders	1.2%
763	Mental Retardation	1.2%
764	Muscle Weakness	1.2%
765	Depressed Level of Consciousness	1.2%
766	Mental deficiency	1.2%
767	Intellectual Disability	1.2%
768	Mobius Syndrome	1.2%
769	Bell Palsy	1.2%
770	Catatonia	1.2%
771	Herpes Zoster Oticus	1.2%
772	Familial Periodic Paralysis	1.2%
773	Aphonia	1.2%
774	Sleep Deprivation	1.2%
775	Dysphonia	1.2%
776	Gaucher Disease	1.2%
777	Cubital Tunnel Syndrome	1.1%
778	Myalgia	1%
779	Neuronal Ceroid-Lipofuscinoses	1%
780	Classical Lissencephalies and Subcortical Band Heterotopias	1%
781	Tay-Sachs Disease	1%
782	Esotropia	1%
783	Exotropia	1%
784	Sleep Apnea Syndromes	1%
785	Polymyositis	1%
786	Disorders of Excessive Somnolence	1%
787	Sleep Initiation and Maintenance Disorders	1%
788	Night Terrors	1%
789	Somnambulism	1%
790	Trigeminal Nerve Disorder	1%
791	Transient Insomnia	1%
792	Sleep Paralysis	1%
793	Chronic Insomnia	1%
794	REM Sleep Behavior Disorder	1%
795	Hypersomnia	1%
796	Dermal Sinus	1%
797	Dysgeusia	1%
798	Formication	1%
799	Hyperalgesia	1%
800	Hyperesthesia	1%
801	Hypesthesia	1%
802	Language Disorders	1%
803	Numbness	1%
804	Paresthesia	1%
805	Paraparesis, Spastic	1%
806	Spina Bifida Cystica	1%
807	Trismus	1%
808	Spina Bifida Occulta	1%
809	Epilepsia Partialis Continua	1%
810	Hypogeusia	1%
811	Meningeal Carcinomatosis	1%
812	Brown-Sequard Syndrome	1%
813	Lissencephaly	1%
814	Polymicrogyria	1%
815	Pachygyria	1%
816	Schizencephaly	1%
817	Lockjaw	1%
818	Allodynia	1%
819	Lead Poisoning, Nervous System, Childhood	1%
820	Lead Poisoning, Nervous System, Adult	1%
821	Periventricular Nodular Heterotopia	1%
822	Ageusia	1%
823	Niemann-Pick Disease, Type C	1%
824	Aicardi's syndrome	0.9%
825	Hoarseness	0.9%
826	Cockayne Syndrome	0.9%
827	Alcohol Withdrawal Delirium	0.9%
828	Eye Injuries	0.8%
829	Muscular Dystrophy	0.8%
830	Congenital nystagmus	0.8%
831	Orbital Myositis	0.8%
832	Holoprosencephaly	0.8%
833	Diplopia	0.8%
834	Muscle Rigidity	0.8%
835	Muscle Spasticity	0.8%
836	Scotoma	0.8%
837	Photophobia	0.8%
838	Cogwheel Rigidity	0.8%
839	Hemifacial Spasm	0.8%
840	Amaurosis	0.8%
841	Blindness	0.8%
842	Nuchal Rigidity	0.8%
843	Pyomyositis	0.8%
844	Optic Atrophy, Hereditary, Leber	0.8%
845	Agnosia	0.8%
846	Apraxias	0.8%
847	Hallucinations	0.8%
848	Hemianopsia	0.8%
849	Hyperacusis	0.8%
850	Tinnitus	0.8%
851	Visual Agnosia	0.8%
852	Anosognosia	0.8%
853	Wernicke-Korsakoff Syndrome	0.8%
854	Phonophobia	0.8%
855	Hearing Loss	0.8%
856	Sarcopenia	0.8%
857	Alexia	0.8%
858	Polyradiculopathy	0.8%
859	Dyslexia	0.8%
860	Amnesia	0.7%
861	Delirium	0.7%
862	Dissociative Amnesia	0.7%
863	Color blindness	0.7%
864	Global Amnesia	0.7%
865	Cri-du-Chat Syndrome	0.7%
866	Down Syndrome	0.7%
867	Trisomy 21	0.7%
868	POEMS Syndrome	0.7%
869	Neurofibrosarcoma	0.7%
870	Meningioma	0.7%
871	Microcephaly	0.7%
872	Macrocephaly	0.7%
873	Hypokalemic periodic paralysis	0.7%
874	Porencephaly	0.7%
875	Sleep Apnea, Obstructive	0.6%
876	Sleep Apnea, Central	0.6%
877	Narcolepsy	0.6%
878	Trigeminal Neuralgia	0.6%
879	Kleine-Levin Syndrome	0.6%
880	Agraphia	0.6%
881	Anomia	0.6%
882	Cluttering	0.6%
883	Language Development Disorders	0.6%
884	Speech Disorders	0.6%
885	Syncope	0.6%
886	Stupor	0.6%
887	Dysgraphia	0.6%
888	Presyncope	0.6%
889	Dyslalia	0.6%
890	Prader-Willi Syndrome	0.6%
891	Phantom pain	0.6%
892	Phantom Limb Pain	0.6%
893	Eye Burns	0.5%
894	Welander Distal Myopathy	0.5%
895	Amaurosis Fugax	0.5%
896	Blindness, Cortical	0.5%
897	Dyscalculia	0.5%
898	Rett Syndrome	0.5%
899	Deafness	0.5%
900	Hearing Loss, Sudden	0.5%
901	Gerstmann Syndrome	0.5%
902	Hearing Loss, Bilateral	0.5%
903	Hearing Loss, High-Frequency	0.5%
904	Hearing Loss, Mixed Conductive-Sensorineural	0.5%
905	Prosopagnosia	0.5%
906	Apraxia, Ideomotor	0.5%
907	Charles Bonnet Syndrome	0.5%
908	Hearing Loss, Unilateral	0.5%
909	Complete Hearing Loss	0.5%
910	Alien Hand Syndrome	0.5%
911	Deaf Mutism	0.5%
912	Rubinstein-Taybi Syndrome	0.5%
913	Cataplexy	0.5%
914	Aphasia	0.5%
915	Articulation Disorders	0.5%
916	Echolalia	0.5%
917	Stuttering	0.5%
918	Dysphasia	0.5%
919	Dermatomyositis	0.5%
920	Corneal Scar	0.5%
921	Muscular Dystrophy, Duchenne	0.5%
922	Retrograde amnesia	0.5%
923	Amnesia, Anterograde	0.5%
924	Mutism	0.4%
925	Selective Mutism	0.4%
926	Fragile X Syndrome	0.4%
927	Dysarthria	0.4%
928	Corneal Perforation	0.3%
929	Alexia, Pure	0.3%
930	Mucopolysaccharidosis II	0.3%

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