MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypohidrosis

(UMLS:C0020620)

Definition:: Abnormally diminished or absent perspiration. Both generalized and segmented (reduced or absent sweating in circumscribed locations) forms of the disease are usually associated with other underlying conditions.
UMLS ID:: C0020620
MeSH ID:: D007007

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.946.370

Synonym(s)

Hypohidrosis

HYPOHIDROSIS

Hypohydrosis

OLIGIDRIA

Oligohidrosis

hypohidrosis

oligohidrosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Topiramate	FAERS: 29 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
2	Finasteride	FAERS: 10		US FAERS
3	Lamotrigine	FAERS: 6		US FAERS
4	Zonisamide	FAERS: 5		US FAERS
5	Thyroxine	FAERS: 4		US FAERS
6	fesoterodine	FAERS: 4		US FAERS
7	Duloxetine Hydrochloride	FAERS: 3		US FAERS
8	Amoxicillin-Potassium Clavulanate Combination	FAERS: 2		US FAERS
9	Bexarotene	FAERS: 2		US FAERS
10	Erlotinib Hydrochloride	FAERS: 2		US FAERS
11	Gabapentin	FAERS: 2		US FAERS
12	Risperidone	FAERS: 2		SIDER US FAERS
13	Solifenacin Succinate	FAERS: 2		US FAERS
14	Sunitinib	FAERS: 2		US FAERS
15	Triamcinolone Acetonide	FAERS: 2		US FAERS
16	oxybutynin	FAERS: 2		SIDER US FAERS
17	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 1		US FAERS
18	Amlodipine	FAERS: 1		US FAERS
19	Aripiprazole	FAERS: 1		US FAERS
20	Asenapine	FAERS: 1		US FAERS
21	Canagliflozin	FAERS: 1		US FAERS
22	Capecitabine	FAERS: 1		US FAERS
23	Droxidopa	FAERS: 1		US FAERS
24	Duavee	FAERS: 1		US FAERS
25	Enalapril	FAERS: 1		US FAERS
26	Levofloxacin	FAERS: 1		US FAERS
27	Lisdexamfetamine Dimesylate	FAERS: 1		US FAERS
28	Lurasidone Hydrochloride	FAERS: 1		US FAERS
29	Morphine	FAERS: 1		US FAERS
30	Moxifloxacin	FAERS: 1		US FAERS
31	Moxifloxacin	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
32	Pregabalin	FAERS: 1		SIDER US FAERS
33	Qlaira	FAERS: 1		US FAERS
34	Ruxolitinib phosphate	FAERS: 1		US FAERS
35	Thyroxine	FAERS: 1		US FAERS
36	Tolterodine Tartrate	FAERS: 1		US FAERS
37	Varenicline	FAERS: 1		US FAERS
38	Vemurafenib	FAERS: 1		US FAERS
39	lumacaftor, ivacaftor drug combination	FAERS: 1		US FAERS
40	osimertinib	FAERS: 1		US FAERS
41	ziprasidone	FAERS: 1		US FAERS
42	Atropine			SIDER
43	Citalopram	Canada Vigilance: 1		Canada Vigilance
44	Citalopram			SIDER
45	Dicyclomine			SIDER
46	Fluoxetine	Canada Vigilance: 1		Canada Vigilance
47	Glycopyrrolate			SIDER
48	Mepenzolate bromide			SIDER
49	Methotrexate		5501901	CTD
50	N-Methylscopolamine			SIDER
51	PCI 32765	Canada Vigilance: 1		Canada Vigilance
52	Paroxetine			SIDER
53	Propantheline			SIDER
54	Venlafaxine Hydrochloride			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Miliaria	46.7%
2	Hidradenitis	46.7%
3	Miliaria Rubra	46.7%
4	Breast Diseases	31%
5	Dermatitis	31%
6	Exanthema	31%
7	Facial Dermatoses	31%
8	Hair Diseases	31%
9	Hand Dermatoses	31%
10	keratoacanthoma	31%
11	Keratosis	31%
12	Nail Diseases	31%
13	Photosensitivity Disorders	31%
14	Prurigo	31%
15	Pyoderma	31%
16	Rosacea	31%
17	Sebaceous Gland Diseases	31%
18	Skin Diseases, Vesiculobullous	31%
19	Skin Ulcer	31%
20	Skin Diseases, Papulosquamous	31%
21	Skin Diseases, Vascular	31%
22	Acneiform Eruptions	31%
23	Ocular Rosacea	31%
24	Subcorneal pustular dermatosis	31%
25	Erythematotelangiectatic Rosacea	31%
26	Papulopustular Rosacea	31%
27	Chronic Actinic Dermatitis	31%
28	Pyoderma Gangrenosum	30%
29	Lupus Erythematosus, Cutaneous	27.9%
30	Panniculitis	27.9%
31	Systemic Scleroderma	27.9%
32	Morphea	27.9%
33	Acne Vulgaris	26.7%
34	Contact Dermatitis	26.7%
35	Eczema	26.7%
36	Erythema Multiforme	26.7%
37	Intertrigo	26.7%
38	Neurodermatitis	26.7%
39	Rhinophyma	26.7%
40	Perioral Dermatitis	26.7%
41	Acne	26.7%
42	Sweating, Gustatory	23.6%
43	Auriculotemporal Syndrome	23.6%
44	Foot Ulcer	23.1%
45	Foot Diseases	22%
46	Dermatitis, Phototoxic	22%
47	Pityriasis Lichenoides et Varioliformis Acuta	22%
48	Pityriasis Lichenoides	22%
49	Phototoxicity	22%
50	Skin Abnormalities	20.9%
51	Skin Diseases, Infectious	20.9%
52	Skin Neoplasms	20.9%
53	Pigmentation Disorders	20.9%
54	Lipomatosis	20.5%
55	Pruritus	20.5%
56	Erythema	20.5%
57	Necrolytic Migratory Erythema	20.5%
58	Cutaneous Fistula	20.5%
59	Nephrogenic Fibrosing Dermopathy	20.5%
60	Nephrogenic Systemic Fibrosis	20.5%
61	Dermatitis Herpetiformis	20.3%
62	Acrodermatitis	20%
63	Cholesteatoma	20%
64	Pressure Ulcer	20%
65	Dermatitis, Atopic	20%
66	Epidermolysis Bullosa	20%
67	Folliculitis	20%
68	Foot Dermatoses	20%
69	Gynecomastia	20%
70	Hypertrichosis	20%
71	Hypotrichosis	20%
72	Leg Ulcer	20%
73	Parakeratosis	20%
74	Parapsoriasis	20%
75	Pityriasis	20%
76	Psoriasis	20%
77	Sebaceous Gland Neoplasms	20%
78	Sweet Syndrome	20%
79	Onycholysis	20%
80	Hyperpigmentation	20%
81	Porokeratosis	20%
82	Lichenoid Eruptions	20%
83	Gianotti-Crosti Syndrome	20%
84	Chloracne	20%
85	Keratoderma, Palmoplantar	20%
86	Dermatitis, Irritant	19.6%
87	Acne Conglobata	19.6%
88	Connective Tissue Diseases	18.5%
89	Panniculitis, Lupus Erythematosus	18.4%
90	Xeroderma Pigmentosum	17.9%
91	Necrobiosis Lipoidica Diabeticorum	17.9%
92	Lupus Erythematosus, Discoid	17.8%
93	Scleroderma, Limited	17.8%
94	Dermatitis, Photoallergic	17.5%
95	Urticaria Pigmentosa	17.1%
96	Hidradenitis Suppurativa	16.4%
97	Xeroderma	16.2%
98	Dermatomyositis	16.2%
99	Diaper Rash	16.1%
100	Dermatitis, Occupational	15.5%
101	Cutis Laxa	15.3%
102	Mastocytosis	15.1%
103	Lichen Planus	14.8%
104	Melanosis	14.8%
105	Chloasma	14.8%
106	Pityriasis Rosea	14.8%
107	Pityriasis Rubra Pilaris	14.8%
108	Vitiligo	14.8%
109	Dermatitis, Allergic Contact	14.8%
110	Lichen Nitidus	14.8%
111	Papillon-Lefevre Disease	14.6%
112	Erythema Induratum	14.4%
113	Erythema Infectiosum	14.1%
114	Exanthema Subitum	14%
115	Erythema Nodosum	13.7%
116	Acantholysis	13.6%
117	Breast Cyst	13.6%
118	Actinic keratosis	13.6%
119	Pemphigoid, Benign Mucous Membrane	13.6%
120	Pemphigus	13.6%
121	Piedra	13.6%
122	Sunburn	13.6%
123	Argyria	13.3%
124	Ectodermal Dysplasia	13.3%
125	Hirsutism	13.3%
126	Lactation Disorder	13.3%
127	Mastitis	13.3%
128	Urticaria	13.3%
129	Aplasia Cutis Congenita	13.3%
130	Adiposis Dolorosa	13.2%
131	Pruritus Vulvae	13.2%
132	Mastocytoma	13.1%
133	Pruritus Ani	13.1%
134	Tinea Capitis	12.7%
135	Onychomycosis	12.7%
136	Toxic Epidermal Necrolysis	12.6%
137	Stevens-Johnson Syndrome	12.6%
138	Pseudoxanthoma Elasticum	12.6%
139	Granuloma Annulare	12.4%
140	Acanthosis Nigricans	12.2%
141	Alopecia Areata	12.2%
142	Lentigo	12.2%
143	Ecthyma	11.5%
144	Hyperkeratosis, Epidermolytic	11%
145	Collagen Diseases	10.3%
146	Mixed Connective Tissue Disease	10.3%
147	Mucinoses	10.3%
148	Dermatomycoses	10.2%
149	Mucocutaneous Lymph Node Syndrome	10.2%
150	Skin Diseases, Bacterial	10.2%
151	Alopecia	10.1%
152	Androgenetic Alopecia	10.1%
153	Drug Eruptions	10%
154	Lipodystrophy	10%
155	Livedo Reticularis	10%
156	Malignant Atrophic Papulosis	10%
157	Behcet Syndrome	10%
158	Lice Infestations	9.9%
159	Varicose Ulcer	9.9%
160	Breast Neoplasms, Male	9.9%
161	Triple Negative Breast Neoplasms	9.9%
162	Polyarteritis Nodosa	9.8%
163	Takayasu Arteritis	9.8%
164	Ichthyosis, X-Linked	9.8%
165	Galactorrhea	9.8%
166	Sjogren-Larsson Syndrome	9.8%
167	Tinea Pedis	8.9%
168	Albinism	8.7%
169	Erythema Chronicum Migrans	8.5%
170	Lichen Planus, Oral	8.4%
171	Nail-Patella Syndrome	8.2%
172	Porphyrias, Hepatic	8.1%
173	Larva Migrans	7.6%
174	Leishmaniasis	7.6%
175	Molluscum Contagiosum	7.6%
176	Angioedema	7.5%
177	Onchocerciasis	7.5%
178	Chromoblastomycosis	7.4%
179	Dermatophytosis	7.4%
180	Sporotrichosis	7.4%
181	Tinea	7.4%
182	Tinea Versicolor	7.4%
183	Trichophytosis	7.4%
184	Hyalohyphomycosis	7.4%
185	Mycetoma	7.3%
186	Cartilage Diseases	7.3%
187	Rheumatism	7.3%
188	Chondromalacia	7.3%
189	Acute Generalized Exanthematous Pustulosis	7.3%
190	Lupus Erythematosus, Systemic	7%
191	Overlap syndrome	7%
192	Scleromyxedema	6.7%
193	Leishmaniasis, Cutaneous	6.1%
194	Eczema Herpeticum	6.1%
195	Warts	6.1%
196	Fusariosis	6%
197	Candidiasis, Chronic Mucocutaneous	5.9%
198	Cutaneous Candidiasis	5.9%
199	Erysipelas	5.9%
200	Serum Sickness	5.9%
201	Staphylococcal Skin Infections	5.9%
202	Variegate Porphyria	5.9%
203	Acute intermittent porphyria	5.9%
204	Porphyria Cutanea Tarda	5.9%
205	Erythrasma	5.9%
206	Carcinoma, Lobular	5.9%
207	Arthritis, Psoriatic	5.8%
208	CREST Syndrome	5.6%
209	Hereditary Angioedema Type III	5.4%
210	Hereditary Angioedema Types I and II	5.4%
211	Dupuytren Contracture	5%
212	Angioedemas, Hereditary	5%
213	Epidermodysplasia Verruciformis	4.9%
214	Herpes Labialis	4.9%
215	Giant Cell Arteritis	4.9%
216	Temporal Arteritis	4.9%
217	Diabetic Foot	4.9%
218	Staphylococcal Scalded Skin Syndrome	4.8%
219	Mesenteric Panniculitis	4.5%
220	Panniculitis, Peritoneal	4.5%
221	Tietze's Syndrome	4.5%
222	Orbital Cellulitis	4.5%
223	Myxoid cyst	4.5%
224	Peutz-Jeghers Syndrome	4.5%
225	Myxedema	4.4%
226	carbuncle	4.3%
227	Blastomycosis	4.2%
228	HIV-Associated Lipodystrophy Syndrome	4.2%
229	Condylomata Acuminata	4.1%
230	Furunculosis	4.1%
231	furuncle	4.1%
232	Cellulitis	4%
233	Impetigo	4%
234	Rhinoscleroma	3.8%
235	Menkes Kinky Hair Syndrome	3.5%
236	Osteochondritis	3.4%
237	Polymyalgia Rheumatica	3.4%
238	Osteogenesis Imperfecta	3.4%
239	Keloid	3.3%
240	Noonan Syndrome	2.9%
241	Rheumatoid Arthritis	2.7%
242	Juvenile arthritis	2.7%
243	Lupus Nephritis	2.6%
244	Marfan Syndrome	2.5%
245	Rheumatoid Nodule	2.5%
246	Homocystinuria	2.4%
247	Laryngomalacia	2.3%
248	Pectus carinatum	2.3%
249	Felty Syndrome	2%
250	Bronchomalacia	2%
251	Tracheomalacia	2%
252	Rheumatoid Vasculitis	1.6%
253	Mucopolysaccharidosis III	1.6%
254	Sicca Syndrome	1.4%
255	Sjogren's Syndrome	1.4%
256	Lupus Vasculitis, Central Nervous System	1.1%
257	Mucopolysaccharidosis II	1.1%

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