MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Collagen Diseases

(UMLS:C0009326)

Definition:: Historically, a heterogeneous group of acute and chronic diseases, including rheumatoid arthritis, systemic lupus erythematosus, progressive systemic sclerosis, dermatomyositis, etc. This classification was based on the notion that "collagen" was equivalent to "connective tissue", but with the present recognition of the different types of collagen and the aggregates derived from them as distinct entities, the term "collagen diseases" now pertains exclusively to those inherited conditions in which the primary defect is at the gene level and affects collagen biosynthesis, post-translational modification, or extracellular processing directly. (From Cecil Textbook of Medicine, 19th ed, p1494)
UMLS ID:: C0009326
MeSH ID:: D003095

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.200

Synonym(s)

Collagen Diseases

COLLAGEN DISORDER

Collagen Disease

Collagen Vascular Disease

Collagen disease

Collagen disease, NOS

Collagen diseases

Collagen disorder

Collagen disorder, NOS

10.

Disease;collagen

11.

Musculoskeletal Pain Disorder

12.

RHEUMATOLOGIC PROBLEM

13.

Rheumatic Disease

14.

Rheumatism

15.

Rheumatologic Disorder

16.

collagen disease

17.

collagen diseases

18.

collagen disorder

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Prednisolone		2792461	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Mixed Connective Tissue Disease	42.9%
2	Mucinoses	42.9%
3	Lupus Erythematosus, Cutaneous	38.1%
4	Panniculitis	38.1%
5	Systemic Scleroderma	38.1%
6	Morphea	38.1%
7	Scleromyxedema	31%
8	Cartilage Diseases	30%
9	Rheumatism	30%
10	Chondromalacia	30%
11	Panniculitis, Lupus Erythematosus	29.3%
12	Lupus Erythematosus, Systemic	28.6%
13	Overlap syndrome	28.6%
14	Lupus Erythematosus, Discoid	27.3%
15	Scleroderma, Limited	27.3%
16	Cutis Laxa	25.9%
17	Dermatomyositis	21.8%
18	Mesenteric Panniculitis	20.9%
19	Panniculitis, Peritoneal	20.9%
20	Tietze's Syndrome	20.9%
21	Orbital Cellulitis	20.9%
22	Myxoid cyst	20.9%
23	Myxedema	20.5%
24	Dupuytren Contracture	20.4%
25	Cellulitis	16.3%
26	Osteochondritis	15.8%
27	Polymyalgia Rheumatica	15.8%
28	Pyoderma Gangrenosum	15.3%
29	Pseudoxanthoma Elasticum	15.2%
30	Breast Diseases	14.3%
31	Dermatitis	14.3%
32	Exanthema	14.3%
33	Facial Dermatoses	14.3%
34	Hair Diseases	14.3%
35	Hand Dermatoses	14.3%
36	keratoacanthoma	14.3%
37	Keratosis	14.3%
38	Nail Diseases	14.3%
39	Photosensitivity Disorders	14.3%
40	Prurigo	14.3%
41	Pyoderma	14.3%
42	Rosacea	14.3%
43	Sebaceous Gland Diseases	14.3%
44	Skin Diseases, Vesiculobullous	14.3%
45	Skin Ulcer	14.3%
46	Sweat Gland Diseases	14.3%
47	Skin Diseases, Papulosquamous	14.3%
48	Skin Diseases, Vascular	14.3%
49	Acneiform Eruptions	14.3%
50	Ocular Rosacea	14.3%
51	Subcorneal pustular dermatosis	14.3%
52	Erythematotelangiectatic Rosacea	14.3%
53	Papulopustular Rosacea	14.3%
54	Chronic Actinic Dermatitis	14.3%
55	Erythema Induratum	14.1%
56	Acne Vulgaris	13.6%
57	Contact Dermatitis	13.6%
58	Eczema	13.6%
59	Erythema Multiforme	13.6%
60	Intertrigo	13.6%
61	Neurodermatitis	13.6%
62	Rhinophyma	13.6%
63	Perioral Dermatitis	13.6%
64	Acne	13.6%
65	Rheumatoid Arthritis	12.5%
66	Rheumatoid Nodule	12.5%
67	Juvenile arthritis	12.5%
68	Dermatitis, Phototoxic	12.4%
69	Pityriasis Lichenoides et Varioliformis Acuta	12.4%
70	Pityriasis Lichenoides	12.4%
71	Phototoxicity	12.4%
72	Foot Ulcer	12.4%
73	Lupus Nephritis	11.9%
74	Noonan Syndrome	11.5%
75	Dermatitis, Irritant	11.1%
76	Acne Conglobata	11.1%
77	Laryngomalacia	10.5%
78	Anhidrosis	10.3%
79	Cholesteatoma	10.3%
80	Pressure Ulcer	10.3%
81	Dermatitis Herpetiformis	10.3%
82	Folliculitis	10.3%
83	Foot Dermatoses	10.3%
84	Gynecomastia	10.3%
85	Hypertrichosis	10.3%
86	Hypohidrosis	10.3%
87	Hypotrichosis	10.3%
88	Leg Ulcer	10.3%
89	Miliaria	10.3%
90	Parakeratosis	10.3%
91	Parapsoriasis	10.3%
92	Pityriasis	10.3%
93	Psoriasis	10.3%
94	Sweet Syndrome	10.3%
95	Hidradenitis	10.3%
96	Onycholysis	10.3%
97	Miliaria Rubra	10.3%
98	Hyperpigmentation	10.3%
99	Lichenoid Eruptions	10.3%
100	Chloracne	10.3%
101	Pectus carinatum	10.3%
102	Marfan Syndrome	10.2%
103	Acrodermatitis	10.2%
104	Sebaceous Gland Neoplasms	10.2%
105	Porokeratosis	10.2%
106	Gianotti-Crosti Syndrome	10.2%
107	Keratoderma, Palmoplantar	10.2%
108	Dermatitis, Atopic	10.1%
109	Epidermolysis Bullosa	10.1%
110	Felty Syndrome	10%
111	Foot Diseases	10%
112	Bronchomalacia	10%
113	Tracheomalacia	10%
114	Diaper Rash	9.9%
115	Dermatitis, Photoallergic	9.9%
116	Homocystinuria	9.9%
117	Skin Abnormalities	9.5%
118	Skin Diseases, Infectious	9.5%
119	Skin Neoplasms	9.5%
120	Pigmentation Disorders	9.5%
121	CREST Syndrome	9.4%
122	Lipomatosis	9.3%
123	Pruritus	9.3%
124	Erythema	9.3%
125	Necrolytic Migratory Erythema	9.3%
126	Cutaneous Fistula	9.3%
127	Nephrogenic Fibrosing Dermopathy	9.3%
128	Nephrogenic Systemic Fibrosis	9.3%
129	Urticaria Pigmentosa	9.1%
130	Xeroderma Pigmentosum	9%
131	Dermatitis, Occupational	8.8%
132	Lichen Planus	8.5%
133	Melanosis	8.5%
134	Chloasma	8.5%
135	Pityriasis Rosea	8.5%
136	Pityriasis Rubra Pilaris	8.5%
137	Vitiligo	8.5%
138	Lichen Nitidus	8.5%
139	Dermatitis, Allergic Contact	8.3%
140	Rheumatoid Vasculitis	8.3%
141	Papillon-Lefevre Disease	8.3%
142	Xeroderma	8.2%
143	Mucopolysaccharidosis III	8.1%
144	Necrobiosis Lipoidica Diabeticorum	8.1%
145	Acanthosis Nigricans	7.6%
146	Alopecia Areata	7.6%
147	Lentigo	7.6%
148	Erythema Infectiosum	7.5%
149	Exanthema Subitum	7.4%
150	Erythema Nodosum	7.3%
151	Sicca Syndrome	7.1%
152	Sjogren's Syndrome	7.1%
153	Toxic Epidermal Necrolysis	7%
154	Stevens-Johnson Syndrome	7%
155	Acantholysis	7%
156	Breast Cyst	7%
157	Actinic keratosis	7%
158	Pemphigoid, Benign Mucous Membrane	7%
159	Pemphigus	7%
160	Piedra	7%
161	Sunburn	7%
162	Tinea Capitis	6.9%
163	Onychomycosis	6.9%
164	Mastocytosis	6.8%
165	Argyria	6.8%
166	Hirsutism	6.8%
167	Lactation Disorder	6.8%
168	Mastitis	6.8%
169	Urticaria	6.8%
170	Adiposis Dolorosa	6.7%
171	Ectodermal Dysplasia	6.7%
172	Pruritus Vulvae	6.7%
173	Aplasia Cutis Congenita	6.7%
174	Mastocytoma	6.7%
175	Pruritus Ani	6.7%
176	Hyperkeratosis, Epidermolytic	6.5%
177	Ecthyma	6.1%
178	Alopecia	5.7%
179	Sweating, Gustatory	5.7%
180	Androgenetic Alopecia	5.7%
181	Auriculotemporal Syndrome	5.7%
182	Lice Infestations	5.6%
183	Varicose Ulcer	5.6%
184	Breast Neoplasms, Male	5.6%
185	Triple Negative Breast Neoplasms	5.6%
186	Galactorrhea	5.6%
187	Hidradenitis Suppurativa	5.5%
188	Mucopolysaccharidosis II	5.4%
189	Ichthyosis, X-Linked	5.3%
190	Behcet Syndrome	5.3%
191	Sjogren-Larsson Syndrome	5.2%
192	Dermatomycoses	5.2%
193	Mucocutaneous Lymph Node Syndrome	5.2%
194	Skin Diseases, Bacterial	5.2%
195	Tinea Pedis	5.2%
196	Lichen Planus, Oral	5.1%
197	Drug Eruptions	5.1%
198	Lipodystrophy	5.1%
199	Livedo Reticularis	5.1%
200	Malignant Atrophic Papulosis	5.1%
201	Granuloma Annulare	5%
202	Polyarteritis Nodosa	5%
203	Takayasu Arteritis	5%
204	Lupus Vasculitis, Central Nervous System	4.9%
205	Albinism	4.6%
206	Erythema Chronicum Migrans	4.5%
207	Larva Migrans	4.3%
208	Leishmaniasis	4.3%
209	Molluscum Contagiosum	4.3%
210	Angioedema	4.2%
211	Onchocerciasis	4.2%
212	Chromoblastomycosis	4.2%
213	Dermatophytosis	4.2%
214	Nail-Patella Syndrome	4.2%
215	Sporotrichosis	4.2%
216	Tinea	4.2%
217	Tinea Versicolor	4.2%
218	Trichophytosis	4.2%
219	Hyalohyphomycosis	4.2%
220	Acute Generalized Exanthematous Pustulosis	4.1%
221	Porphyrias, Hepatic	4.1%
222	Mycetoma	4.1%
223	Leishmaniasis, Cutaneous	3.7%
224	Eczema Herpeticum	3.7%
225	Fusariosis	3.7%
226	Hereditary Angioedema Type III	3.5%
227	Hereditary Angioedema Types I and II	3.5%
228	Warts	3.4%
229	Candidiasis, Chronic Mucocutaneous	3.3%
230	Cutaneous Candidiasis	3.3%
231	Erysipelas	3.3%
232	Serum Sickness	3.3%
233	Staphylococcal Skin Infections	3.3%
234	Variegate Porphyria	3.3%
235	Acute intermittent porphyria	3.3%
236	Porphyria Cutanea Tarda	3.3%
237	Erythrasma	3.3%
238	Carcinoma, Lobular	3.3%
239	Arthritis, Psoriatic	3.3%
240	Angioedemas, Hereditary	3%
241	Epidermodysplasia Verruciformis	3%
242	Herpes Labialis	3%
243	Diabetic Foot	3%
244	Staphylococcal Scalded Skin Syndrome	2.9%
245	Peutz-Jeghers Syndrome	2.9%
246	carbuncle	2.7%
247	Condylomata Acuminata	2.5%
248	Furunculosis	2.5%
249	furuncle	2.5%
250	Giant Cell Arteritis	2.5%
251	Temporal Arteritis	2.5%
252	Impetigo	2.4%
253	Blastomycosis	2.4%
254	HIV-Associated Lipodystrophy Syndrome	2.3%
255	Rhinoscleroma	2.1%
256	Menkes Kinky Hair Syndrome	1.8%

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