MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Mycetoma

(UMLS:C0024449)

Definition:: A chronic progressive subcutaneous infection caused by species of fungi (eumycetoma), or actinomycetes (actinomycetoma). It is characterized by tumefaction, abscesses, and tumor-like granules representing microcolonies of pathogens, such as MADURELLA fungi and bacteria ACTINOMYCETES, with different grain colors.
UMLS ID:: C0024449
MeSH ID:: D008271

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.410.040.692.606|C01.252.825.557|C01.539.800.200.500|C01.539.800.720.557|C01.703.295.522

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.838.208.557|C17.800.838.765.557

Synonym(s)

Mycetoma

Mycetoma, NOS

Mycetoma, unspecified

Mycetomata

fungal mycetoma

madura foot

maduramycosis

maduromycosis

mycetoma

10.

mycetomas

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Itraconazole	22205798 22760037	CTD
2	Ketoconazole	22205798 22760037	CTD
3	Voriconazole	22205798 22760037	CTD
4	posaconazole	22205798 22760037	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Ecthyma	50.3%
2	Erythrasma	49.9%
3	Erysipelas	49.5%
4	Staphylococcal Skin Infections	49.5%
5	Hidradenitis Suppurativa	49.3%
6	Erythema Chronicum Migrans	47.9%
7	Candidiasis, Chronic Mucocutaneous	47.6%
8	Cutaneous Candidiasis	47.6%
9	Chromoblastomycosis	44.2%
10	Dermatophytosis	44.2%
11	Sporotrichosis	44.2%
12	Tinea	44.2%
13	Tinea Versicolor	44.2%
14	Trichophytosis	44.2%
15	Hyalohyphomycosis	44.2%
16	Impetigo	40.6%
17	Blastomycosis	40.4%
18	Erythema Induratum	38.6%
19	Rhinoscleroma	37.1%
20	Staphylococcal Scalded Skin Syndrome	36.5%
21	Tinea Capitis	35.2%
22	Onychomycosis	35.2%
23	Furunculosis	33.7%
24	furuncle	33.7%
25	Fusariosis	32.8%
26	Tinea Pedis	30.6%
27	carbuncle	30.1%
28	Cellulitis	27.2%
29	Skin Diseases, Bacterial	27%
30	Mycetoma	26.5%
31	Bacteremia	24.9%
32	Central Nervous System Bacterial Infections	24.5%
33	Dermatomycoses	24.1%
34	Bacterial Endocarditis	22.9%
35	Syphilis	22.4%
36	Borrelia Infections	21.4%
37	Leptospirosis	21.4%
38	Lyme Neuroborreliosis	20.9%
39	Piedra	20.7%
40	Subacute Bacterial Endocarditis	20.5%
41	Ulcerative stomatitis	20.4%
42	Lyme Disease	19.9%
43	Relapsing Fever	19.9%
44	Gram-Negative Bacterial Infections	19.5%
45	Candidemia	19.4%
46	Pelvic Infection	19.1%
47	Wound Infection	19.1%
48	Soft Tissue Infection	19.1%
49	Community-Acquired Infections	19.1%
50	Chlamydia Infections	18.8%
51	Gonorrhea	18.8%
52	Neurosyphilis	18.1%
53	Pyoderma Gangrenosum	17.7%
54	Central Nervous System Infection	17.4%
55	Eye Infection	17.4%
56	Respiratory Tract Infections	17.4%
57	Bacterial Vaginosis	17.3%
58	Fungemia	17.3%
59	Bone Diseases, Infectious	17.1%
60	Pregnancy Complications, Infectious	17.1%
61	Arthritis, Infectious	17%
62	Suppuration	17%
63	Cross Infection	16.9%
64	Septicemia	16.9%
65	Sepsis	16.9%
66	Joint Tuberculosis	16.7%
67	Tuberculosis, Osteoarticular	16.7%
68	Bone Tuberculosis	16.7%
69	Pertussis	16.1%
70	Clostridium Infections	16.1%
71	Listeriosis	16.1%
72	Staphylococcal Infections	16.1%
73	Streptococcal Infections	16.1%
74	Bacillaceae Infections	16.1%
75	Clostridium difficile infection	16.1%
76	Neuroaspergillosis	16%
77	Opportunistic Infections	16%
78	Xeroderma Pigmentosum	15.9%
79	Aspergillosis	15.8%
80	Candidiasis	15.8%
81	Coccidioidomycosis	15.8%
82	Histoplasmosis	15.8%
83	Paracoccidioidomycosis	15.8%
84	Zygomycosis	15.8%
85	Phaeohyphomycosis	15.8%
86	Pneumocystis Infections	15.8%
87	Panophthalmitis	15.7%
88	Pneumonia, Bacterial	15.7%
89	Actinomycosis	15.6%
90	Corynebacterium Infections	15.6%
91	Mycobacterium Infections	15.6%
92	Endotoxemia	15.6%
93	Urinary tract infection	15.4%
94	Mycoses	15.2%
95	Human Ehrlichiosis	14.8%
96	Dermatitis, Atopic	14.8%
97	Epidermolysis Bullosa	14.8%
98	Lupus Erythematosus, Cutaneous	14.7%
99	Panniculitis	14.7%
100	Systemic Scleroderma	14.7%
101	Morphea	14.7%
102	Erysipelothrix infection	14.7%
103	Hordeolum	14.6%
104	Bacterial conjunctivitis	14.6%
105	Sexually Transmitted Diseases	14.3%
106	Otomycosis	14.2%
107	Central Nervous System Fungal Infections	14.1%
108	Gram-Positive Bacterial Infections	14%
109	Meningitis, Listeria	13.8%
110	Lymphogranuloma Venereum	13.8%
111	Brain Abscess	13.8%
112	Erythema Infectiosum	13.8%
113	Exanthema Subitum	13.7%
114	Invasive Pulmonary Aspergillosis	13.7%
115	Human anaplasmosis	13.6%
116	Japanese Spotted Fever	13.1%
117	Acne Vulgaris	13.1%
118	Contact Dermatitis	13.1%
119	Eczema	13.1%
120	Erythema Multiforme	13.1%
121	Intertrigo	13.1%
122	Neurodermatitis	13.1%
123	Rhinophyma	13.1%
124	Perioral Dermatitis	13.1%
125	Acne	13.1%
126	Ophthalmia Neonatorum	12.9%
127	Trachoma	12.9%
128	Lung Diseases, Fungal	12.9%
129	Meningitis, Cryptococcal	12.4%
130	Breast Diseases	12.3%
131	Dermatitis	12.3%
132	Exanthema	12.3%
133	Facial Dermatoses	12.3%
134	Hair Diseases	12.3%
135	Hand Dermatoses	12.3%
136	keratoacanthoma	12.3%
137	Keratosis	12.3%
138	Nail Diseases	12.3%
139	Photosensitivity Disorders	12.3%
140	Prurigo	12.3%
141	Pyoderma	12.3%
142	Rosacea	12.3%
143	Sebaceous Gland Diseases	12.3%
144	Skin Diseases, Vesiculobullous	12.3%
145	Skin Ulcer	12.3%
146	Sweat Gland Diseases	12.3%
147	Skin Diseases, Papulosquamous	12.3%
148	Skin Diseases, Vascular	12.3%
149	Acneiform Eruptions	12.3%
150	Ocular Rosacea	12.3%
151	Subcorneal pustular dermatosis	12.3%
152	Erythematotelangiectatic Rosacea	12.3%
153	Papulopustular Rosacea	12.3%
154	Chronic Actinic Dermatitis	12.3%
155	Bordetella Infections	12%
156	Brucellosis	12%
157	Campylobacter infection	12%
158	Enterobacteriaceae Infections	12%
159	Pseudomonas Infections	12%
160	Q Fever	12%
161	Vibrio Infections	12%
162	Helicobacter Infections	12%
163	Neisseriaceae Infections	12%
164	Burkholderia Infections	12%
165	Flavobacteriaceae Infections	12%
166	Moraxellaceae Infections	12%
167	Burkholderia cepacia Infection	12%
168	Dermatomyositis	12%
169	Infection	11.9%
170	Meningitis, Pneumococcal	11.9%
171	Necrobiosis Lipoidica Diabeticorum	11.9%
172	Dermatitis Herpetiformis	11.9%
173	Panniculitis, Lupus Erythematosus	11.9%
174	Acrodermatitis	11.8%
175	Sebaceous Gland Neoplasms	11.8%
176	Porokeratosis	11.8%
177	Gianotti-Crosti Syndrome	11.8%
178	Keratoderma, Palmoplantar	11.8%
179	Bacterial Infections	11.7%
180	Dermatitis, Phototoxic	11.7%
181	Pityriasis Lichenoides et Varioliformis Acuta	11.7%
182	Pityriasis Lichenoides	11.7%
183	Phototoxicity	11.7%
184	Tuberculosis, Spinal	11.6%
185	Diphtheria	11.3%
186	Leprosy	11.3%
187	Mycobacterium Infections, Nontuberculous	11.3%
188	Tuberculosis	11.3%
189	Mycobacterium abscessus Infection	11.3%
190	Foot Diseases	11.2%
191	Skin Abnormalities	11%
192	Skin Neoplasms	11%
193	Pigmentation Disorders	11%
194	Lipomatosis	11%
195	Pruritus	11%
196	Erythema	11%
197	Necrolytic Migratory Erythema	11%
198	Cutaneous Fistula	11%
199	Nephrogenic Fibrosing Dermopathy	11%
200	Nephrogenic Systemic Fibrosis	11%
201	Tuberculosis, Meningeal	10.9%
202	Foot Ulcer	10.8%
203	Pseudoxanthoma Elasticum	10.8%
204	Xeroderma	10.8%
205	Gas Gangrene	10.8%
206	Pneumococcal Infections	10.8%
207	Scarlet Fever	10.8%
208	Tetanus	10.8%
209	Meningitis, Haemophilus	10.7%
210	Rocky Mountain Spotted Fever	10.7%
211	Dermatitis, Photoallergic	10.6%
212	Syphilis, Congenital	10.4%
213	Endophthalmitis	10.4%
214	Peritonitis	10.4%
215	Osteomyelitis	10.3%
216	Periostitis	10.3%
217	Surgical Wound Infection	10.3%
218	Abscess	10.3%
219	Adnexitis	10.3%
220	Empyema	10.3%
221	Pelvic Inflammatory Disease	10.3%
222	Lice Infestations	10.1%
223	Mucormycosis	10%
224	Mastocytosis	9.9%
225	Ectodermal Dysplasia	9.8%
226	Aplasia Cutis Congenita	9.8%
227	Urticaria Pigmentosa	9.7%
228	Meningitis, Bacterial	9.6%
229	Superinfection	9.5%
230	Corneal Ulcer	9.4%
231	Puerperal Infection	9.3%
232	Spondylitis	9.3%
233	Appendicitis	9.3%
234	Bacteriuria	9.3%
235	Pyuria	9.3%
236	Pyomyositis	9.3%
237	Endotoxic shock	9.3%
238	Septic Shock	9.3%
239	Toxic Shock Syndrome	9.3%
240	Cutis Laxa	9.2%
241	Mycobacterium avium-intracellulare Infection	9.2%
242	Lymph Node Tuberculosis	9.2%
243	Tuberculosis, Miliary	9.2%
244	Tuberculosis, Multidrug-Resistant	9.2%
245	Leprosy, Multibacillary	9.2%
246	Latent Tuberculosis	9.2%
247	Larva Migrans	9.2%
248	Leishmaniasis	9.2%
249	Molluscum Contagiosum	9.2%
250	Onchocerciasis	9.1%
251	Toxic Epidermal Necrolysis	9%
252	Stevens-Johnson Syndrome	9%
253	Actinomycetales Infections	9%
254	Oral candidiasis	9%
255	Pulmonary Aspergillosis	8.9%
256	Bronchopulmonary Aspergillosis	8.9%
257	Erythema Nodosum	8.9%
258	Lupus Erythematosus, Discoid	8.7%
259	Scleroderma, Limited	8.7%
260	Rheumatic Fever	8.7%
261	Dermatitis, Irritant	8.6%
262	Acne Conglobata	8.6%
263	Enterocolitis, Pseudomembranous	8.6%
264	pseudomembranous colitis	8.6%
265	Ichthyosis, X-Linked	8.6%
266	Sjogren-Larsson Syndrome	8.5%
267	Warts	8.4%
268	Arthritis, Reactive	8.4%
269	Acinetobacter Infections	8.3%
270	Bacteroides Infections	8.3%
271	Cholera	8.3%
272	Escherichia coli Infections	8.3%
273	Haemophilus Infections	8.3%
274	Klebsiella Infections	8.3%
275	Meningococcal Infections	8.3%
276	Mycoplasma Infections	8.3%
277	Pasteurella Infections	8.3%
278	Proteus Infections	8.3%
279	Rickettsia Infections	8.3%
280	Salmonella infections	8.3%
281	Scrub Typhus	8.3%
282	Serratia Infections	8.3%
283	Ureaplasma Infections	8.3%
284	Tuberculosis, Gastrointestinal	8.3%
285	Tuberculosis, Central Nervous System	8.2%
286	Borderline leprosy	8.1%
287	Leprosy, Lepromatous	8.1%
288	Tuberculoid leprosy	8.1%
289	Extensively Drug-Resistant Tuberculosis	8.1%
290	Meningitis, Fungal	8%
291	Dermatitis, Occupational	8%
292	Candidiasis, Vulvovaginal	7.9%
293	Botulism	7.9%
294	Psoas Abscess	7.9%
295	Abdominal Abscess	7.9%
296	AIDS-Related Opportunistic Infections	7.9%
297	Dermatitis, Allergic Contact	7.8%
298	Papillon-Lefevre Disease	7.8%
299	Behcet Syndrome	7.6%
300	Connective Tissue Diseases	7.5%
301	Tuberculosis, Pulmonary	7.5%
302	Hyperkeratosis, Epidermolytic	7.4%
303	Anhidrosis	7.3%
304	Cholesteatoma	7.3%
305	Pressure Ulcer	7.3%
306	Folliculitis	7.3%
307	Foot Dermatoses	7.3%
308	Gynecomastia	7.3%
309	Hypertrichosis	7.3%
310	Hypohidrosis	7.3%
311	Hypotrichosis	7.3%
312	Leg Ulcer	7.3%
313	Miliaria	7.3%
314	Parakeratosis	7.3%
315	Parapsoriasis	7.3%
316	Pityriasis	7.3%
317	Psoriasis	7.3%
318	Sweet Syndrome	7.3%
319	Hidradenitis	7.3%
320	Onycholysis	7.3%
321	Miliaria Rubra	7.3%
322	Hyperpigmentation	7.3%
323	Lichenoid Eruptions	7.3%
324	Chloracne	7.3%
325	Toxoplasmosis, Cerebral	7.3%
326	Rheumatic Heart Disease	7.3%
327	Granuloma Annulare	7.2%
328	Albinism	7%
329	Diverticulitis	7%
330	Leishmaniasis, Cutaneous	6.8%
331	Eczema Herpeticum	6.8%
332	Dysentery, Bacillary	6.6%
333	Acantholysis	6.6%
334	Breast Cyst	6.6%
335	Actinic keratosis	6.6%
336	Pemphigoid, Benign Mucous Membrane	6.6%
337	Pemphigus	6.6%
338	Sunburn	6.6%
339	Argyria	6.5%
340	Hirsutism	6.5%
341	Lactation Disorder	6.5%
342	Mastitis	6.5%
343	Urticaria	6.5%
344	Adiposis Dolorosa	6.5%
345	Pruritus Vulvae	6.5%
346	Mastocytoma	6.5%
347	Pruritus Ani	6.5%
348	Nocardia Infections	6.5%
349	Pulmonary Nocardiosis	6.5%
350	Psittacosis	6.5%
351	Paratyphoid Fever	6.5%
352	Plague	6.5%
353	Typhoid Fever	6.5%
354	TYPHUS	6.5%
355	Yersinia pseudotuberculosis Infections	6.5%
356	Bubonic Plague	6.5%
357	Diaper Rash	6.5%
358	Lung Abscess	6.4%
359	Diverticulum	6.4%
360	Diverticulosis	6.4%
361	Discitis	6.3%
362	Mastoiditis	6.3%
363	Petrositis	6.3%
364	Epidermodysplasia Verruciformis	6.2%
365	Herpes Labialis	6.2%
366	Skin Diseases, Infectious	6.1%
367	Waterhouse-Friderichsen Syndrome	6%
368	Mucocutaneous Lymph Node Syndrome	5.9%
369	Salmonella Infections, Animal	5.9%
370	Drug Eruptions	5.9%
371	Lipodystrophy	5.9%
372	Livedo Reticularis	5.9%
373	Malignant Atrophic Papulosis	5.9%
374	Polyarteritis Nodosa	5.9%
375	Takayasu Arteritis	5.9%
376	Retropharyngeal Abscess	5.8%
377	Epidural Abscess	5.8%
378	Salmonella food poisoning	5.8%
379	Peritonsillar Abscess	5.7%
380	Condylomata Acuminata	5.7%
381	Tuberculosis, Renal	5.5%
382	Liver Abscess	5.5%
383	Nail-Patella Syndrome	5.4%
384	Porphyrias, Hepatic	5.4%
385	Lichen Planus	4.9%
386	Melanosis	4.9%
387	Chloasma	4.9%
388	Pityriasis Rosea	4.9%
389	Pityriasis Rubra Pilaris	4.9%
390	Vitiligo	4.9%
391	Lichen Nitidus	4.9%
392	Aspergillosis, Allergic Bronchopulmonary	4.8%
393	Alopecia	4.4%
394	Sweating, Gustatory	4.4%
395	Androgenetic Alopecia	4.4%
396	Auriculotemporal Syndrome	4.4%
397	Varicose Ulcer	4.3%
398	Breast Neoplasms, Male	4.3%
399	Triple Negative Breast Neoplasms	4.3%
400	Galactorrhea	4.3%
401	Giant Cell Arteritis	4.2%
402	Temporal Arteritis	4.2%
403	Collagen Diseases	4.1%
404	Mixed Connective Tissue Disease	4.1%
405	Mucinoses	4.1%
406	Lemierre Syndrome	4%
407	CREST Syndrome	4%
408	Angioedema	3.9%
409	Acute Generalized Exanthematous Pustulosis	3.9%
410	Cartilage Diseases	3.7%
411	Rheumatism	3.7%
412	Chondromalacia	3.7%
413	Lupus Erythematosus, Systemic	3.7%
414	Overlap syndrome	3.7%
415	Acanthosis Nigricans	3.6%
416	Alopecia Areata	3.6%
417	Lentigo	3.6%
418	Serum Sickness	3.5%
419	Variegate Porphyria	3.5%
420	Acute intermittent porphyria	3.5%
421	Porphyria Cutanea Tarda	3.5%
422	Carcinoma, Lobular	3.5%
423	Arthritis, Psoriatic	3.5%
424	Liver Abscess, Amebic	3.5%
425	Menkes Kinky Hair Syndrome	3.4%
426	Dupuytren Contracture	3.3%
427	Lichen Planus, Oral	3.3%
428	HIV-Associated Lipodystrophy Syndrome	3%
429	Angioedemas, Hereditary	2.7%
430	Diabetic Foot	2.7%
431	Noonan Syndrome	2.5%
432	Scleromyxedema	2.4%
433	Hereditary Angioedema Type III	2.4%
434	Hereditary Angioedema Types I and II	2.4%
435	Marfan Syndrome	2.4%
436	Homocystinuria	2.3%
437	Peutz-Jeghers Syndrome	2.2%
438	Mesenteric Panniculitis	2.2%
439	Panniculitis, Peritoneal	2.2%
440	Tietze's Syndrome	2.2%
441	Orbital Cellulitis	2.2%
442	Myxoid cyst	2.2%
443	Myxedema	2.2%
444	Osteochondritis	2%
445	Polymyalgia Rheumatica	2%
446	Osteogenesis Imperfecta	2%
447	Keloid	2%
448	Rheumatoid Arthritis	1.8%
449	Juvenile arthritis	1.8%
450	Lupus Nephritis	1.8%
451	Laryngomalacia	1.7%
452	Pectus carinatum	1.7%
453	Rheumatoid Nodule	1.3%
454	Felty Syndrome	1.2%
455	Bronchomalacia	1.2%
456	Tracheomalacia	1.2%
457	Rheumatoid Vasculitis	1.1%
458	Lupus Vasculitis, Central Nervous System	1.1%
459	Mucopolysaccharidosis III	1.1%
460	Sicca Syndrome	1%
461	Sjogren's Syndrome	1%
462	Mucopolysaccharidosis II	0.9%

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