MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Heart Rupture, Post-Infarction

(UMLS:C0018814)

Definition:: Laceration or tearing of cardiac tissues appearing after MYOCARDIAL INFARCTION.
UMLS ID:: C0018814
MeSH ID:: D006342

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.470.475

Synonym(s)

Heart Rupture, Post-Infarction

MYOCARDIAL RUPTURE (POST INFARCT)

Post Infarct Cardiac Rupture

Associated Drug(s)

	Name	Reference(s)	Data Source
1	4-phenylbutyric acid	25450231	CTD
2	Atropine	10668020	CTD
3	Cocaine	1469169	CTD
4	Dobutamine	9518421 10668020 10789822	CTD
5	Donepezil	21750701	CTD
6	Prednisone	15219313	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cardiac Tamponade	31%
2	Endocarditis	31%
3	Cardiac Arrest	31%
4	Heart failure	31%
5	Pericardial effusion	31%
6	Pericarditis	31%
7	Pneumopericardium	31%
8	Cor pulmonale	31%
9	Ventricular Outflow Obstruction	31%
10	Ventricular Dysfunction	31%
11	Cardiomyopathies	31%
12	Pleuropericarditis	31%
13	Myocardial Ischemia	27.9%
14	Aortic Valve Stenosis	26.7%
15	Cardiomyopathy, Dilated	26.7%
16	Pulmonary Valve Stenosis	26.7%
17	Hypertrophic Cardiomyopathy	21.3%
18	Hypertrophic obstructive cardiomyopathy	21.3%
19	Cardiac Output, High	20.9%
20	Myocardial Stunning	20.9%
21	Low Cardiac Output Syndrome	20.9%
22	Cardiomegaly	20.5%
23	Postpericardiotomy Syndrome	20.5%
24	Cardiac Hypertrophy	20.5%
25	Rheumatic Heart Disease	20.1%
26	Aortic Valve Insufficiency	20%
27	Restrictive cardiomyopathy	20%
28	Endocardial Fibroelastosis	20%
29	Heart Block	20%
30	Mitral Valve Insufficiency	20%
31	Mitral Valve Stenosis	20%
32	Myocarditis	20%
33	Pericarditis, Constrictive	20%
34	Pulmonary Valve Insufficiency	20%
35	Tachycardia	20%
36	Tricuspid Valve Insufficiency	20%
37	Tricuspid Valve Stenosis	20%
38	Tachyarrhythmia	20%
39	Ventricular Dysfunction, Left	20%
40	Right Ventricular Dysfunction	20%
41	Endomyocardial Fibrosis	20%
42	Carditis	20%
43	Heart Failure, Systolic	20%
44	Heart Failure, Diastolic	20%
45	Supravalvular aortic stenosis	19.6%
46	Lown-Ganong-Levine Syndrome	19.6%
47	Tricuspid Atresia	18.5%
48	Arrhythmogenic Right Ventricular Dysplasia	18.5%
49	Vascular Diseases	18.5%
50	Coronary heart disease	17.8%
51	Myocardial Infarction	17.8%
52	Acute Coronary Syndrome	17.8%
53	Myocardial Reperfusion Injury	17.7%
54	Long QT Syndrome	15.9%
55	Aortic Valve Prolapse	14.8%
56	Tricuspid Valve Prolapse	14.8%
57	Takotsubo Cardiomyopathy	14.8%
58	Adams-Stokes Syndrome	14.6%
59	Atrioventricular Block	14.6%
60	Bundle-Branch Block	14.6%
61	Atrial Premature Complexes	14.6%
62	Sinoatrial Block	14.6%
63	Tachycardia, Paroxysmal	14.6%
64	Supraventricular tachycardia	14.6%
65	Tachycardia, Ventricular	14.6%
66	Wolff-Parkinson-White Syndrome	14.6%
67	Tachycardia, Reciprocating	14.6%
68	Sick Sinus Syndrome	14.6%
69	Kounis Syndrome	13.6%
70	Sinus Arrhythmia	13.3%
71	Atrial Fibrillation	13.3%
72	Atrial Flutter	13.3%
73	Edema, Cardiac	13.3%
74	Ventricular Fibrillation	13.3%
75	Ventricular Flutter	13.3%
76	Parasystole	13.3%
77	Paroxysmal atrial fibrillation	13.3%
78	Bradycardia	13.3%
79	Diabetic Cardiomyopathies	13.3%
80	Aortic coarctation	13.2%
81	Cor Triatriatum	13.2%
82	Coronary Vessel Anomalies	13.2%
83	Patent ductus arteriosus	13.2%
84	Ebstein Anomaly	13.2%
85	Heart Septal Defects	13.2%
86	Tetralogy of Fallot	13.2%
87	Transposition of Great Vessels	13.2%
88	Hypoplastic Left Heart Syndrome	13.2%
89	Cardiomyopathy, Alcoholic	13.2%
90	Sudden Cardiac Death	13.2%
91	Left Ventricular Hypertrophy	13.2%
92	Right Ventricular Hypertrophy	13.2%
93	Angina Pectoris	13.2%
94	Chagas Cardiomyopathy	13.1%
95	Coronary Aneurysm	13.1%
96	Coronary Occlusion	13%
97	Microvascular Angina	13%
98	Coronary Stenosis	13%
99	ST segment elevation myocardial infarction	13%
100	Bacterial Endocarditis	12.3%
101	Coronary Thrombosis	12.2%
102	Pregnancy Complications, Cardiovascular	12.2%
103	Cardiovascular Abnormalities	12.2%
104	Coronary Artery Disease	12.2%
105	Tachycardia, Atrioventricular Nodal Reentry	12%
106	Tachycardia, Ectopic Atrial	12%
107	Tachycardia, Ectopic Junctional	12%
108	Sinus Tachycardia	12%
109	Torsades de Pointes	12%
110	Accelerated Idioventricular Rhythm	12%
111	Carcinoid Heart Disease	11.7%
112	Romano-Ward Syndrome	11.7%
113	Coronary Restenosis	10.8%
114	Dextrocardia	10.6%
115	Aneurysm	10.3%
116	Angiomatosis	10.3%
117	Aortic Diseases	10.3%
118	Arterial Occlusive Diseases	10.3%
119	Hyperemia	10.3%
120	Hypotension	10.3%
121	Superior Vena Cava Syndrome	10.3%
122	Telangiectasis	10.3%
123	Vasculitis	10.3%
124	Venous Insufficiency	10.3%
125	Peripheral Vascular Diseases	10.3%
126	Embolism and Thrombosis	10.3%
127	Angiodysplasia	10.3%
128	Capillary Leak Syndrome	10.3%
129	Prehypertension	10.3%
130	Dyspnea, Paroxysmal	9.9%
131	Shock, Cardiogenic	9.8%
132	Sinus Arrest, Cardiac	9.8%
133	Aortopulmonary Septal Defect	9.7%
134	Double Outlet Right Ventricle	9.7%
135	Endocardial Cushion Defects	9.7%
136	Myocardial bridging	9.7%
137	Aorticopulmonary Septal Defect	9.7%
138	Angina, Unstable	9.7%
139	Aortic Aneurysm	8.9%
140	Aortitis	8.9%
141	Leriche Syndrome	8.9%
142	Periphlebitis	8.9%
143	Phlebitis	8.9%
144	Thromboangiitis Obliterans	8.9%
145	Truncus Arteriosus, Persistent	8%
146	Angina Pectoris, Variant	8%
147	Postphlebitic Syndrome	7.7%
148	Noonan Syndrome	7.6%
149	Embolism, Amniotic Fluid	7.6%
150	Vascular System Injuries	7.3%
151	Retinal Vein Occlusion	7.2%
152	Subacute Bacterial Endocarditis	7.1%
153	Compartment syndromes	7%
154	Hepatic Veno-Occlusive Disease	7%
155	Peliosis Hepatis	7%
156	Varicocele	7%
157	Thrombophlebitis	6.9%
158	Cerebrovascular Disorders	6.8%
159	Diabetic Angiopathies	6.8%
160	Reperfusion Injury	6.8%
161	Splenic Infarction	6.8%
162	Cerebrovascular Insufficiency	6.8%
163	Vascular Neoplasms	6.8%
164	Spinal Cord Vascular Diseases	6.8%
165	Vasoplegia	6.8%
166	Blue Toe Syndrome	6.8%
167	Marfan Syndrome	6.8%
168	Hemorrhoids	6.7%
169	Thoracic Outlet Syndrome	6.7%
170	Aneurysm, Dissecting	6.7%
171	Arteriosclerosis	6.7%
172	Arteritis	6.7%
173	Embolism	6.7%
174	Erythromelalgia	6.7%
175	Fibromuscular Dysplasia	6.7%
176	Malignant Hypertension	6.7%
177	Raynaud Disease	6.7%
178	Thromboembolism	6.7%
179	Thrombosis	6.7%
180	Essential Hypertension	6.7%
181	Aneurysm, Ruptured	6.7%
182	Iliac Aneurysm	6.7%
183	Malignant Atrophic Papulosis	6.7%
184	Pulmonary artery stenosis	6.7%
185	White Coat Hypertension	6.7%
186	Systemic Vasculitis	6.7%
187	Embolus	6.7%
188	Shwartzman Phenomenon	6.6%
189	May-Thurner Syndrome	6.6%
190	Arteriovenous fistula	6.5%
191	Aortic Aneurysm, Abdominal	6.5%
192	Aortic Aneurysm, Thoracic	6.5%
193	Aortic Rupture	6%
194	Intracranial Embolism and Thrombosis	5.7%
195	Carotid Stenosis	5.7%
196	Intracranial Aneurysm	5.7%
197	Carotid Artery Thrombosis	5.5%
198	Hand-Arm Vibration Syndrome	5.4%
199	Optic Neuropathy, Ischemic	5.2%
200	Anterior Ischemic Optic Neuropathy	5.2%
201	Mesenteric vascular insufficiency	5.2%
202	Moyamoya Disease	5.1%
203	Angioedema	5%
204	Colitis, Ischemic	5%
205	Arteriosclerosis Obliterans	4.9%
206	Atherosclerosis	4.9%
207	Air Embolism	4.9%
208	Endarteritis	4.9%
209	Polyarteritis Nodosa	4.9%
210	Takayasu Arteritis	4.9%
211	Venous Thrombosis	4.9%
212	Deep Vein Thrombosis	4.9%
213	Williams Syndrome	4.9%
214	Venous Thromboembolism	4.9%
215	Scimitar Syndrome	4.9%
216	Intracranial Arteriosclerosis	4.9%
217	Cerebral Atherosclerosis	4.9%
218	Cerebral Arteriosclerosis	4.9%
219	Retinal Artery Occlusion	4.5%
220	Retinal Vasculitis	4.5%
221	Hypertensive Retinopathy	4.5%
222	Vasculitis, Central Nervous System	4.5%
223	Anterior Compartment Syndrome	4.4%
224	Vasculitis, Leukocytoclastic, Cutaneous	4.4%
225	Gastric Antral Vascular Ectasia	4.4%
226	Abdominal Compartment Syndrome	4.4%
227	Cerebral Thrombosis	4.4%
228	Intracranial Embolism	4.4%
229	Intracranial Thrombosis	4.4%
230	Carotid Artery Diseases	4.4%
231	Brain Ischemia	4.4%
232	Ectopia Cordis	4.4%
233	Hypotension, Orthostatic	4.4%
234	Cerebrovascular accident	4.4%
235	Varicose Ulcer	4.4%
236	Vasospasm, Intracranial	4.4%
237	Spinal Cord Ischemia	4.4%
238	Intracranial Arterial Diseases	4.4%
239	Primary Graft Dysfunction	4.4%
240	Single umbilical artery	4.4%
241	Post-Exercise Hypotension	4.4%
242	Brain Infarction	3.9%
243	Sinus Thrombosis, Intracranial	3.8%
244	Turner Syndrome	3.7%
245	Giant Cell Arteritis	3.7%
246	Temporal Arteritis	3.7%
247	Kearns-Sayre syndrome	3.5%
248	Cavernous Sinus Thrombosis	3.5%
249	Sagittal Sinus Thrombosis	3.5%
250	Lemierre Syndrome	3.4%
251	Mesenteric Vascular Occlusion	3.4%
252	Mucocutaneous Lymph Node Syndrome	3.4%
253	Intermittent Claudication	3.4%
254	Pulmonary Embolism	3.4%
255	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.4%
256	Diabetic Retinopathy	3.4%
257	Sturge-Weber Syndrome	3.4%
258	Livedo Reticularis	3.3%
259	Renal hypertension	3.3%
260	Renal Artery Obstruction	3.3%
261	Renal Artery Stenosis	3.3%
262	No-Reflow Phenomenon	3.3%
263	Hemangioma, Cavernous	3.3%
264	Basal Ganglia Cerebrovascular Disease	3.3%
265	Vertebral Artery Dissection	3.3%
266	Vascular Headaches	3.3%
267	Scurvy	3.3%
268	CREST Syndrome	3.2%
269	Cerebral Arterial Diseases	3.2%
270	Vertebrobasilar Insufficiency	3.2%
271	Anterior Spinal Artery Syndrome	3.2%
272	Basilar Artery Stenosis	3.2%
273	Vertebral Artery Stenosis	3.2%
274	Intracranial Hemorrhage, Hypertensive	3.2%
275	Transient Cerebral Ischemia	3.2%
276	Subarachnoid Hemorrhage, Traumatic	3.2%
277	Carotid Artery, Internal, Dissection	3.2%
278	Cerebral Infarction	3.2%
279	Brain Stem Infarctions	3.2%
280	Infarction, Middle Cerebral Artery	3.2%
281	Infarction, Anterior Cerebral Artery	3.2%
282	Infarction, Posterior Cerebral Artery	3.2%
283	Kartagener Syndrome	3.1%
284	Lateral Medullary Syndrome	2.9%
285	Hepatic Vein Thrombosis	2.8%
286	Budd-Chiari Syndrome	2.8%
287	Carotid Artery Injuries	2.8%
288	Pulmonary Infarction	2.7%
289	Dural Arteriovenous Fistula	2.7%
290	Subclavian Steal Syndrome	2.7%
291	Ischemic contracture	2.7%
292	Angioedemas, Hereditary	2.6%
293	Cryoglobulinemia	2.6%
294	Leukomalacia, Periventricular	2.6%
295	Diabetic Foot	2.6%
296	Basal Ganglia Hemorrhage	2.5%
297	Hypertension, Renovascular	2.4%
298	Subarachnoid Hemorrhage	2.4%
299	Hypoxia-Ischemia, Brain	2.4%
300	Cerebral Hemorrhage	2.4%
301	Hereditary Angioedema Type III	2.4%
302	Hereditary Angioedema Types I and II	2.4%
303	Shy-Drager Syndrome	2.2%
304	Purpura, Hyperglobulinemic	2.2%
305	Putaminal Hemorrhage	2.2%
306	Granulomatosis with polyangiitis	2.1%
307	Dementia, Vascular	2%
308	Cerebral Amyloid Angiopathy	2%
309	Pituitary Apoplexy	2%
310	Behcet Syndrome	1.9%
311	Waldenstrom Macroglobulinemia	1.9%
312	Multiple Myeloma	1.9%
313	Ataxia Telangiectasia	1.7%
314	Pseudoxanthoma Elasticum	1.7%
315	Rheumatoid Vasculitis	1.6%
316	Lupus Vasculitis, Central Nervous System	1.6%
317	Hematoma, Subdural	1.2%
318	Hematoma, Epidural, Cranial	1.2%
319	Hematoma, Subdural, Intracranial	1%
320	Hematoma, Subdural, Chronic	1%
321	Hematoma, Subdural, Acute	1%
322	Brain Hemorrhage, Traumatic	1%
323	MELAS Syndrome	1%
324	Fabry Disease	0.7%

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