MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vertebral Artery Dissection

(UMLS:C0338586)

Definition:: Splitting of the vessel wall in the VERTEBRAL ARTERY. Interstitial hemorrhage into the media of the vessel wall can lead to occlusion of the vertebral artery, aneurysm formation, or THROMBOEMBOLISM. Vertebral artery dissection is often associated with TRAUMA and injuries to the head-neck region but can occur spontaneously.
UMLS ID:: C0338586
MeSH ID:: D020217

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.350.875|C10.900.250.650

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.055.050.575|C14.907.253.535.800

Classification 3:

Name:

Wounds and Injuries
MeSH Tree Number(s):: C26.915.200.600

Synonym(s)

Vertebral Artery Dissection

Dissection of vertebral artery

Vertebral artery dissection

dissection of vertebral artery

vertebral artery dissection

vertebral dissection artery

Associated Drug(s)

	Name	Number of Reports	Data Source
1	NuvaRing	FAERS: 16	US FAERS
2	Fingolimod Hydrochloride	FAERS: 6	US FAERS
3	Norgestrel	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
4	apixaban	FAERS: 3	US FAERS
5	Rivaroxaban	FAERS: 2	US FAERS
6	lenvatinib	FAERS: 2	US FAERS
7	zolmitriptan	FAERS: 2	US FAERS
8	Albuterol	FAERS: 1	US FAERS
9	Dabigatran	FAERS: 1	US FAERS
10	Dimethyl Fumarate	FAERS: 1	US FAERS
11	Ethinyl Estradiol-Norgestrel Combination	FAERS: 1	US FAERS
12	Lisdexamfetamine Dimesylate	FAERS: 1	US FAERS
13	Rosiglitazone	FAERS: 1	US FAERS
14	Sildenafil Citrate	FAERS: 1	US FAERS
15	Sildenafil Citrate	FAERS: 1	US FAERS
16	Sumatriptan	FAERS: 1	US FAERS
17	Testosterone	FAERS: 1	US FAERS
18	etonogestrel	FAERS: 1	US FAERS
19	Albuterol	Canada Vigilance: 1	Canada Vigilance

Similar ADE(s)

	Name	Semantic Similarity
1	Carotid Artery Injuries	48.9%
2	Carotid Artery, Internal, Dissection	43%
3	Subarachnoid Hemorrhage, Traumatic	30.2%
4	Basal Ganglia Cerebrovascular Disease	28.1%
5	Vasculitis, Central Nervous System	27.8%
6	Intracranial Embolism and Thrombosis	27.5%
7	Intracranial Aneurysm	27.4%
8	Moyamoya Disease	27.2%
9	Brain Infarction	26.9%
10	Vascular Headaches	26.4%
11	Carotid Artery Diseases	25.9%
12	Brain Ischemia	25.9%
13	Cerebrovascular accident	25.9%
14	Vasospasm, Intracranial	25.9%
15	Intracranial Arterial Diseases	25.9%
16	Leukomalacia, Periventricular	25%
17	Dementia, Vascular	24.2%
18	Carotid Artery Thrombosis	23.9%
19	Carotid Stenosis	22.6%
20	Aortic Aneurysm	22.5%
21	Infarction, Middle Cerebral Artery	22.2%
22	Infarction, Anterior Cerebral Artery	22.2%
23	Infarction, Posterior Cerebral Artery	22.2%
24	Basal Ganglia Hemorrhage	22.1%
25	Brain Hemorrhage, Traumatic	21.8%
26	Aortic Rupture	21.1%
27	Hypoxia-Ischemia, Brain	20.6%
28	Cerebral Infarction	20.4%
29	Brain Stem Infarctions	20.4%
30	Intracranial Arteriosclerosis	20%
31	Cerebral Atherosclerosis	20%
32	Cerebral Arteriosclerosis	20%
33	Brain Injuries	19.7%
34	Peripheral Nerve Injuries	19.6%
35	Spinal Cord Vascular Diseases	19.6%
36	Vascular System Injuries	19.5%
37	Craniocerebral Trauma	19.3%
38	Pneumocephalus	19.1%
39	Myocardial Ischemia	19.1%
40	Cerebral Thrombosis	18.8%
41	Intracranial Embolism	18.8%
42	Intracranial Thrombosis	18.8%
43	Coronary Aneurysm	18.7%
44	Spinal Cord Injuries	18.7%
45	Giant Cell Arteritis	18.4%
46	Temporal Arteritis	18.4%
47	Putaminal Hemorrhage	17.4%
48	Lupus Vasculitis, Central Nervous System	17.4%
49	Cerebral Arterial Diseases	17.4%
50	Vertebrobasilar Insufficiency	17.4%
51	Basilar Artery Stenosis	17.4%
52	Vertebral Artery Stenosis	17.4%
53	Intracranial Hemorrhage, Hypertensive	17.4%
54	Transient Cerebral Ischemia	17.4%
55	Lateral Medullary Syndrome	17.1%
56	Pituitary Apoplexy	17.1%
57	Aortitis	16.9%
58	Leriche Syndrome	16.9%
59	Periphlebitis	16.9%
60	Phlebitis	16.9%
61	Thromboangiitis Obliterans	16.9%
62	Epilepsy, Post-Traumatic	16.8%
63	Angiomatosis	16.5%
64	Aortic Diseases	16.5%
65	Arterial Occlusive Diseases	16.5%
66	Hyperemia	16.5%
67	Hypotension	16.5%
68	Superior Vena Cava Syndrome	16.5%
69	Telangiectasis	16.5%
70	Vasculitis	16.5%
71	Venous Insufficiency	16.5%
72	Peripheral Vascular Diseases	16.5%
73	Embolism and Thrombosis	16.5%
74	Angiodysplasia	16.5%
75	Capillary Leak Syndrome	16.5%
76	Prehypertension	16.5%
77	Aneurysm, Ruptured	16.3%
78	Iliac Aneurysm	16.3%
79	Thoracic Outlet Syndrome	16.2%
80	Retinal Vein Occlusion	16.2%
81	Meningoencephalitis	16%
82	Myocardial Reperfusion Injury	15.8%
83	Hand-Arm Vibration Syndrome	15.5%
84	Multiple System Atrophy	15.4%
85	Optic Neuropathy, Ischemic	15.2%
86	Anterior Ischemic Optic Neuropathy	15.2%
87	Subarachnoid Hemorrhage	15.2%
88	Cerebral Hemorrhage	15.2%
89	Shy-Drager Syndrome	15%
90	Aortic Aneurysm, Abdominal	14.8%
91	Aortic Aneurysm, Thoracic	14.8%
92	Malignant Atrophic Papulosis	14.8%
93	Shwartzman Phenomenon	14.7%
94	Encephalomyelitis	14.7%
95	Sinus Thrombosis, Intracranial	14.5%
96	Brain Concussion	14.4%
97	Compartment syndromes	14.3%
98	Hepatic Veno-Occlusive Disease	14.3%
99	Peliosis Hepatis	14.3%
100	Varicocele	14.3%
101	Diabetic Angiopathies	14.2%
102	Reperfusion Injury	14.2%
103	Splenic Infarction	14.2%
104	Vascular Neoplasms	14.2%
105	Vasoplegia	14.2%
106	Hemorrhoids	14.1%
107	Hematoma, Subdural	14.1%
108	Hematoma, Epidural, Cranial	14.1%
109	Postphlebitic Syndrome	14%
110	Dandy-Walker Syndrome	13.7%
111	Subdural Effusion	13.5%
112	Lewy Body Disease	13.4%
113	Brain Injuries, Diffuse	13.4%
114	Traumatic Brain Injury	13.4%
115	Thrombophlebitis	13.4%
116	Subclavian Steal Syndrome	13.1%
117	Arteriovenous fistula	13%
118	Ocular Motility Disorders	12.8%
119	Cyclophoria	12.8%
120	Mesenteric vascular insufficiency	12.5%
121	Facial Injuries	12.4%
122	Cavernous Sinus Thrombosis	12.3%
123	Sagittal Sinus Thrombosis	12.3%
124	Angioedema	12.3%
125	Colitis, Ischemic	12.3%
126	Brain Abscess	12.1%
127	Stiff-Person Syndrome	12.1%
128	Coma, Post-Head Injury	12%
129	Spinal Cord Ischemia	11.9%
130	Blue Toe Syndrome	11.8%
131	Autonomic Dysreflexia	11.8%
132	Olfactory Nerve Injuries	11.8%
133	Sturge-Weber Syndrome	11.8%
134	Akinetic Mutism	11.7%
135	Anoxic Encephalopathy	11.7%
136	Basal Ganglia Diseases	11.7%
137	Brain Damage, Chronic	11.7%
138	Cerebellar Diseases	11.7%
139	Encephalitis	11.7%
140	Encephalomalacia	11.7%
141	Epilepsy	11.7%
142	Hydrocephalus	11.7%
143	Congenital Hydrocephalus	11.7%
144	Hypothalamic Diseases	11.7%
145	Thalamic Diseases	11.7%
146	Intracranial Hypertension	11.7%
147	Aura	11.7%
148	Leukoencephalopathy	11.7%
149	Neuroaxonal Dystrophies	11.7%
150	Headache Disorders	11.7%
151	Intracranial Hypotension	11.7%
152	Brain Edema	11.7%
153	Brain Hypoxia	11.7%
154	Aqueductal Stenosis	11.7%
155	Hematoma, Subdural, Intracranial	11.7%
156	Hematoma, Subdural, Chronic	11.7%
157	Hematoma, Subdural, Acute	11.7%
158	Parkinsonian Disorders	11.7%
159	MELAS Syndrome	11.6%
160	Central Cord Syndrome	11.5%
161	Cerebral Amyloid Angiopathy	11.5%
162	Brain Neoplasms	11.5%
163	Coronary Thrombosis	11.4%
164	Coronary Artery Disease	11.4%
165	Marchiafava-Bignami Disease	11.3%
166	Parkinson Disease	11.3%
167	Coronary heart disease	11.2%
168	Myocardial Infarction	11.2%
169	Acute Coronary Syndrome	11.2%
170	Epidural Abscess	11.1%
171	Progressive supranuclear palsy	11%
172	Scimitar Syndrome	11%
173	Ataxia Telangiectasia	10.8%
174	Subacute Combined Degeneration	10.8%
175	Myelitis	10.8%
176	Meningitis	10.7%
177	Movement Disorders	10.7%
178	Pachymeningitis	10.7%
179	Spinal Cord Diseases	10.7%
180	Posterior Leukoencephalopathy Syndrome	10.6%
181	Posterior reversible encephalopathy syndrome	10.6%
182	Facial Nerve Injuries	10.6%
183	Huntington Disease	10.6%
184	Brain Contusion	10.6%
185	Hypotension, Orthostatic	10.5%
186	Post-Exercise Hypotension	10.5%
187	Cranial nerve diseases	10.4%
188	Demyelinating Diseases	10.4%
189	Demyelination	10.4%
190	Neuromuscular Diseases	10.4%
191	Chronobiology Disorders	10.4%
192	Prion Diseases	10.4%
193	Diffuse Axonal Injury	10.3%
194	Ophthalmoplegic Migraine	10.3%
195	Amyotrophic Lateral Sclerosis	10.2%
196	Brain Diseases, Metabolic	10.2%
197	Dementia	10.2%
198	Heart Diseases	10.1%
199	Striatonigral Degeneration	10.1%
200	Spinal Muscular Atrophy	10.1%
201	Progressive Muscular Atrophy	10.1%
202	Leukoencephalopathy, Progressive Multifocal	10%
203	Motor Neuron Disease	10%
204	Brain Death	10%
205	Dystonia Musculorum Deformans	10%
206	Kounis Syndrome	9.9%
207	Neuroleptic Malignant Syndrome	9.9%
208	Myelinolysis, Central Pontine	9.9%
209	Restless Legs Syndrome	9.8%
210	May-Thurner Syndrome	9.8%
211	Arteriosclerosis	9.8%
212	Arteritis	9.8%
213	Embolism	9.8%
214	Erythromelalgia	9.8%
215	Fibromuscular Dysplasia	9.8%
216	Malignant Hypertension	9.8%
217	Raynaud Disease	9.8%
218	Thromboembolism	9.8%
219	Thrombosis	9.8%
220	Essential Hypertension	9.8%
221	Pulmonary artery stenosis	9.8%
222	White Coat Hypertension	9.8%
223	Systemic Vasculitis	9.8%
224	Embolus	9.8%
225	Angina Pectoris	9.8%
226	Polyarteritis Nodosa	9.8%
227	Takayasu Arteritis	9.8%
228	Meige Syndrome	9.7%
229	Cerebral Ventriculitis	9.7%
230	Leukoencephalitis, Acute Hemorrhagic	9.7%
231	Cerebellar Neoplasms	9.5%
232	Amblyopia	9.5%
233	Central Nervous System Infection	9.5%
234	Polyradiculoneuropathy	9.4%
235	Polyradiculoneuritis	9.4%
236	Cerebrospinal Fluid Otorrhea	9.4%
237	Cerebrospinal Fluid Rhinorrhea	9.4%
238	Poliomyelitis	9.3%
239	Miller Fisher Syndrome	9.2%
240	Asterixis	9.1%
241	Ballismus	9.1%
242	Embolism, Amniotic Fluid	9.1%
243	Nervous System Neoplasms	9%
244	Neurologic Manifestations	9%
245	Neurotoxicity Syndromes	9%
246	Eye Burns	9%
247	Cerebrovascular Disorders	9%
248	Cerebrovascular Insufficiency	9%
249	Limbic Encephalitis	9%
250	CREST Syndrome	8.8%
251	Myoclonic Epilepsy	8.8%
252	Epilepsy, Temporal Lobe	8.8%
253	Epilepsy, Rolandic	8.8%
254	Benign Rolandic Epilepsy	8.8%
255	Pregnancy Complications, Cardiovascular	8.8%
256	Cardiovascular Abnormalities	8.8%
257	Myelitis, Transverse	8.7%
258	Creutzfeldt-Jakob disease	8.6%
259	MPTP Poisoning	8.6%
260	Retinal Artery Occlusion	8.5%
261	Retinal Vasculitis	8.5%
262	Hypertensive Retinopathy	8.5%
263	Anterior Compartment Syndrome	8.4%
264	Vasculitis, Leukocytoclastic, Cutaneous	8.4%
265	Gastric Antral Vascular Ectasia	8.4%
266	Abdominal Compartment Syndrome	8.4%
267	Varicose Ulcer	8.4%
268	Primary Graft Dysfunction	8.4%
269	Hepatolenticular Degeneration	8.4%
270	Chronic Fatigue Syndrome	8.3%
271	Fabry Disease	8.3%
272	Conus Medullaris Syndrome	8.3%
273	Aneurysm	8.3%
274	Presenile dementia	8.2%
275	Senile dementia	8.2%
276	Encephalomyelitis, Acute Disseminated	8.2%
277	Eye Injuries	8.1%
278	Amnesia, Transient Global	8.1%
279	Anterior Spinal Artery Syndrome	8.1%
280	Complex Regional Pain Syndromes	8%
281	Sleep Wake Disorders	8%
282	Opsoclonus-Myoclonus Syndrome	8%
283	Frostbite	7.8%
284	Meningitis, Bacterial	7.8%
285	Meningitis, Fungal	7.8%
286	Lemierre Syndrome	7.6%
287	Guillain-Barre Syndrome	7.5%
288	Canavan Disease	7.5%
289	Alexander Disease	7.5%
290	Mesenteric Vascular Occlusion	7.5%
291	Mucocutaneous Lymph Node Syndrome	7.5%
292	Coronary Occlusion	7.4%
293	Microvascular Angina	7.4%
294	Coronary Stenosis	7.4%
295	ST segment elevation myocardial infarction	7.4%
296	Diabetic Retinopathy	7.4%
297	Pituitary Adenoma	7.4%
298	Pituitary Neoplasms	7.4%
299	Livedo Reticularis	7.4%
300	Dyskinesia, Drug-Induced	7.4%
301	Renal hypertension	7.4%
302	Renal Artery Obstruction	7.4%
303	Renal Artery Stenosis	7.4%
304	Spinal Cord Neoplasms	7.4%
305	Hemangioma, Cavernous	7.3%
306	Cerebral Palsy	7.3%
307	Epilepsies, Partial	7.3%
308	Epilepsy, Generalized	7.3%
309	Pseudotumor Cerebri	7.3%
310	Hypertensive Encephalopathy	7.3%
311	Simple Partial Seizures	7.3%
312	Epilepsy, Reflex	7.3%
313	Headache Disorders, Primary	7.3%
314	Headache Disorders, Secondary	7.3%
315	Medication overuse headache	7.3%
316	Scurvy	7.3%
317	Akathisia, Drug-Induced	7.3%
318	Cerebellar Ataxia	7.3%
319	Supratentorial Neoplasms	7.3%
320	Paraneoplastic Cerebellar Degeneration	7.3%
321	Toxoplasmosis, Cerebral	7.2%
322	Lambert-Eaton Myasthenic Syndrome	7.1%
323	Myasthenia Gravis	7%
324	Lafora Disease	7%
325	Unverricht-Lundborg Syndrome	7%
326	Friedreich Ataxia	7%
327	Juvenile Myoclonic Epilepsy	6.9%
328	Myoclonic Epilepsies, Progressive	6.9%
329	Persistent Vegetative State	6.9%
330	Neuromyelitis Optica	6.6%
331	Ischemic contracture	6.6%
332	Angioedemas, Hereditary	6.6%
333	Tricuspid Atresia	6.6%
334	Arrhythmogenic Right Ventricular Dysplasia	6.6%
335	Cryoglobulinemia	6.5%
336	Shock, Cardiogenic	6.5%
337	Arteriosclerosis Obliterans	6.5%
338	Atherosclerosis	6.5%
339	Air Embolism	6.5%
340	Endarteritis	6.5%
341	Venous Thrombosis	6.5%
342	Deep Vein Thrombosis	6.5%
343	Venous Thromboembolism	6.5%
344	Diabetic Foot	6.5%
345	Pituitary Diseases	6.5%
346	Angina, Unstable	6.5%
347	Sleep Disorders, Circadian Rhythm	6.4%
348	Causalgia	6.3%
349	Kluver-Bucy Syndrome	6.3%
350	Arachnoiditis	6.3%
351	Aseptic Meningitis	6.3%
352	Syringomyelia	6.3%
353	Essential Tremor	6.3%
354	Familial Tremor	6.3%
355	Pneumorrhachis	6.3%
356	Writer's Cramp	6.3%
357	Botulism	6.2%
358	Central Nervous System Cysts	6.2%
359	Progressive bulbar palsy	6.1%
360	Bulbar palsy	6.1%
361	Dural Arteriovenous Fistula	6.1%
362	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6%
363	Tuberculosis, Meningeal	6%
364	Bacterial Endocarditis	5.9%
365	Mitochondrial Encephalomyopathies	5.9%
366	Corneal Scar	5.9%
367	Purpura, Hyperglobulinemic	5.9%
368	Hip Fractures	5.8%
369	Dysautonomia	5.8%
370	Vagus Nerve Disorder	5.8%
371	Glossopharyngeal Neuralgia	5.8%
372	Abducens Nerve Diseases	5.8%
373	Heavy Metal Poisoning, Nervous System	5.8%
374	Neuromuscular Junction Diseases	5.8%
375	Tauopathies	5.8%
376	Trochlear Nerve Diseases	5.8%
377	Peripheral Nervous System Diseases	5.8%
378	Scrapie	5.8%
379	Crush syndrome	5.7%
380	Femoral Fractures	5.7%
381	Tibial Fractures	5.7%
382	Chorea	5.7%
383	Intermittent Claudication	5.6%
384	Pulmonary Embolism	5.6%
385	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5.6%
386	Athletic Injuries	5.6%
387	Hand Injuries	5.6%
388	Soft Tissue Injuries	5.6%
389	Sprain	5.6%
390	Sprains and Strains	5.6%
391	Tendon Injuries	5.6%
392	Laceration	5.6%
393	Wounds, Penetrating	5.6%
394	Heat Cramps	5.6%
395	Rupture	5.6%
396	Aortic Valve Stenosis	5.6%
397	Cardiomyopathy, Dilated	5.6%
398	Pulmonary Valve Stenosis	5.6%
399	Adrenoleukodystrophy	5.6%
400	No-Reflow Phenomenon	5.6%
401	Coronary Restenosis	5.5%
402	Vertebral Artery Dissection	5.5%
403	Reye Syndrome	5.5%
404	Cardiac Tamponade	5.5%
405	Endocarditis	5.5%
406	Cardiac Arrest	5.5%
407	Heart failure	5.5%
408	Pericardial effusion	5.5%
409	Pericarditis	5.5%
410	Pneumopericardium	5.5%
411	Cor pulmonale	5.5%
412	Ventricular Outflow Obstruction	5.5%
413	Ventricular Dysfunction	5.5%
414	Cardiomyopathies	5.5%
415	Pleuropericarditis	5.5%
416	Hepatic Encephalopathy	5.5%
417	Horner Syndrome	5.5%
418	Central Nervous System Fungal Infections	5.4%
419	Behcet Syndrome	5.4%
420	Waldenstrom Macroglobulinemia	5.4%
421	Multiple Myeloma	5.4%
422	Auditory Perceptual Disorders	5.3%
423	Multiple Sclerosis	5.3%
424	Brain Stem Neoplasms	5.2%
425	Medial Tibial Stress Syndrome	5.2%
426	Myasthenia Gravis, Autoimmune, Experimental	5.2%
427	Corneal Perforation	5.1%
428	Tuberous Sclerosis	5.1%
429	Post-Traumatic Headache	5.1%
430	Tension Headache	5.1%
431	Epilepsy, Complex Partial	5.1%
432	Migraine Disorders	5.1%
433	Abdominal Migraine	5.1%
434	Status Migrainosus	5.1%
435	Cervicogenic Headache	5.1%
436	Reflex Sympathetic Dystrophy	5.1%
437	Nocturnal Myoclonus Syndrome	5.1%
438	Myopathy	5.1%
439	Optic Neuropathy	5.1%
440	Subacute Sclerosing Panencephalitis	5.1%
441	Frontotemporal dementia	5%
442	Facial Nerve Diseases	5%
443	Parasomnia	5%
444	Dyssomnias	5%
445	Hip Dislocation	5%
446	Shoulder Dislocation	5%
447	Splenic Rupture	5%
448	Hip Dysplasia	5%
449	Pseudoxanthoma Elasticum	5%
450	Vestibulocochlear Nerve Diseases	5%
451	Decerebrate State	5%
452	Hemiparesis	5%
453	Hydranencephaly	5%
454	Meningism	5%
455	Neural Tube Defects	5%
456	Paresis	5%
457	Seizures	5%
458	Sensation Disorders	5%
459	Tethered Cord Syndrome	5%
460	Central Nervous System Neoplasms	5%
461	Complex partial seizures	5%
462	Iniencephaly	5%
463	Craniorachischisis	5%
464	Exencephaly	5%
465	Monoparesis	5%
466	Septo-Optic Dysplasia	5%
467	Cortical Dysplasia	5%
468	Neurogenic Inflammation	5%
469	Gait Disorders, Neurologic	5%
470	Neuromuscular Manifestations	5%
471	Malformations of Cortical Development	5%
472	Jet Lag Syndrome	4.9%
473	Sweating, Gustatory	4.9%
474	Auriculotemporal Syndrome	4.9%
475	Heart Block	4.9%
476	Tachycardia	4.9%
477	Tachyarrhythmia	4.9%
478	Brain Diseases, Metabolic, Inborn	4.9%
479	Aortic coarctation	4.9%
480	Cor Triatriatum	4.9%
481	Coronary Vessel Anomalies	4.9%
482	Patent ductus arteriosus	4.9%
483	Ebstein Anomaly	4.9%
484	Heart Septal Defects	4.9%
485	Tetralogy of Fallot	4.9%
486	Transposition of Great Vessels	4.9%
487	Hypoplastic Left Heart Syndrome	4.9%
488	Aneurysm, Dissecting	4.9%
489	Carpal Tunnel Syndrome	4.9%
490	Bites and Stings	4.9%
491	Extravasation of Diagnostic and Therapeutic Materials	4.9%
492	Tympanic Membrane Perforation	4.9%
493	Tooth Injuries	4.9%
494	Hypertension, Renovascular	4.9%
495	Torticollis	4.9%
496	Refsum Disease	4.9%
497	Alice in Wonderland Syndrome	4.8%
498	Hereditary Angioedema Type III	4.8%
499	Hereditary Angioedema Types I and II	4.8%
500	Angina Pectoris, Variant	4.8%
501	Asphyxia	4.8%
502	Esophageal Perforation	4.8%
503	Shock, Traumatic	4.8%
504	Central Nervous System Bacterial Infections	4.8%
505	Self Mutilation	4.8%
506	Cardiac Output, High	4.8%
507	Myocardial Stunning	4.8%
508	Low Cardiac Output Syndrome	4.8%
509	Ophthalmoplegia	4.8%
510	External Ophthalmoplegia	4.8%
511	Chilblains	4.7%
512	Cardiomegaly	4.7%
513	Postpericardiotomy Syndrome	4.7%
514	Spinal Fractures	4.7%
515	Cardiac Hypertrophy	4.7%
516	Charcot-Marie-Tooth Disease	4.7%
517	Rheumatic Heart Disease	4.7%
518	Meningitis, Cryptococcal	4.7%
519	Meningitis, Listeria	4.7%
520	Meningitis, Haemophilus	4.7%
521	Meningitis, Pneumococcal	4.7%
522	Acrodynia	4.5%
523	Empty Sella Syndrome	4.5%
524	Hyperpituitarism	4.5%
525	Hypopituitarism	4.5%
526	Hypophysitis	4.5%
527	Pupil Disorders	4.5%
528	Neurobehavioral Manifestations	4.5%
529	Wernicke Encephalopathy	4.4%
530	AIDS Dementia Complex	4.4%
531	Paraneoplastic Encephalomyelitis	4.4%
532	Dextrocardia	4.4%
533	Long QT Syndrome	4.4%
534	Uveomeningoencephalitic Syndrome	4.3%
535	Vertigo	4.3%
536	Alcohol-Induced Disorders, Nervous System	4.3%
537	Vocal Cord Paralysis	4.3%
538	Hepatic Vein Thrombosis	4.2%
539	Budd-Chiari Syndrome	4.2%
540	Choroid Plexus Papilloma	4.2%
541	Trauma, Nervous System	4.2%
542	Drowning	4.2%
543	Hypertrophic Cardiomyopathy	4.2%
544	Pulmonary Infarction	4.2%
545	Hypertrophic obstructive cardiomyopathy	4.2%
546	Brachial Plexus Neuritis	4.2%
547	Neuralgic Amyotrophy	4.2%
548	Kernicterus	4.1%
549	Cluster Headache	4%
550	Migraine with Aura	4%
551	Familial Hemiplegic Migraine	4%
552	Chronic Paroxysmal Hemicrania	4%
553	SUNCT Syndrome	4%
554	Paroxysmal Hemicrania	4%
555	Cubital Tunnel Syndrome	4%
556	Tardive Dyskinesia	4%
557	Myotonia Congenita	4%
558	Neuritis, Autoimmune, Experimental	4%
559	Gait Ataxia	4%
560	Myotonic Dystrophy	4%
561	Voice Disorders	3.9%
562	Voice Disturbance	3.9%
563	Rheumatoid Vasculitis	3.9%
564	Sick Sinus Syndrome	3.9%
565	Smith-Magenis syndrome	3.9%
566	West Nile Fever	3.9%
567	Alcohol Withdrawal Seizures	3.9%
568	Iliotibial Band Syndrome	3.7%
569	Supravalvular aortic stenosis	3.7%
570	Lown-Ganong-Levine Syndrome	3.7%
571	Radiation injury	3.7%
572	Tarsal Tunnel Syndrome	3.7%
573	Cauda Equina Syndrome	3.7%
574	Granulomatosis with polyangiitis	3.7%
575	Optic Nerve Glioma	3.6%
576	Multiple Sclerosis, Chronic Progressive	3.6%
577	Multiple Sclerosis, Relapsing-Remitting	3.6%
578	Carcinoid Heart Disease	3.6%
579	Noonan Syndrome	3.6%
580	Akathisia	3.6%
581	Restlessness	3.6%
582	Psychomotor Agitation	3.6%
583	Kearns-Sayre syndrome	3.6%
584	Neuritis	3.5%
585	Polyneuritis	3.5%
586	Radiculitis	3.5%
587	Polyneuropathy	3.5%
588	Mononeuritis	3.5%
589	Mononeuropathies	3.5%
590	Brachial Plexus Neuropathies	3.5%
591	Radiculopathy	3.5%
592	Mononeuropathy Multiplex	3.5%
593	Nerve Root Compression	3.5%
594	Hyperprolactinemia	3.5%
595	Tuberculosis, Central Nervous System	3.5%
596	Pick Disease of the Brain	3.5%
597	Reflex, Abnormal	3.4%
598	Hyporeflexia	3.4%
599	Hyperreflexia	3.4%
600	Alstrom Syndrome	3.4%
601	Marfan Syndrome	3.3%
602	Human Bite	3.3%
603	Brain Diseases	3.3%
604	Contusions	3.3%
605	Decompression Sickness	3.3%
606	Finger Injuries	3.3%
607	Flail Chest	3.3%
608	Fractures, Closed	3.3%
609	Pathological fracture	3.3%
610	Heart Injuries	3.3%
611	Heat Exhaustion	3.3%
612	Heat Stroke	3.3%
613	Knee Injuries	3.3%
614	Foot Injuries	3.3%
615	Decapitation	3.3%
616	Ankle Fracture	3.3%
617	Avulsion fracture	3.3%
618	Compression fracture	3.3%
619	Osteoporotic Fractures	3.3%
620	Splenosis	3.3%
621	Aortic Valve Insufficiency	3.3%
622	Restrictive cardiomyopathy	3.3%
623	Endocardial Fibroelastosis	3.3%
624	Heart Rupture, Post-Infarction	3.3%
625	Mitral Valve Insufficiency	3.3%
626	Mitral Valve Stenosis	3.3%
627	Myocarditis	3.3%
628	Pericarditis, Constrictive	3.3%
629	Pulmonary Valve Insufficiency	3.3%
630	Tricuspid Valve Insufficiency	3.3%
631	Tricuspid Valve Stenosis	3.3%
632	Ventricular Dysfunction, Left	3.3%
633	Right Ventricular Dysfunction	3.3%
634	Endomyocardial Fibrosis	3.3%
635	Carditis	3.3%
636	Heart Failure, Systolic	3.3%
637	Heart Failure, Diastolic	3.3%
638	Subacute Bacterial Endocarditis	3.3%
639	Adams-Stokes Syndrome	3.2%
640	Atrioventricular Block	3.2%
641	Bundle-Branch Block	3.2%
642	Atrial Premature Complexes	3.2%
643	Sinoatrial Block	3.2%
644	Tachycardia, Paroxysmal	3.2%
645	Supraventricular tachycardia	3.2%
646	Tachycardia, Ventricular	3.2%
647	Wolff-Parkinson-White Syndrome	3.2%
648	Tachycardia, Reciprocating	3.2%
649	Aortopulmonary Septal Defect	3.2%
650	Double Outlet Right Ventricle	3.2%
651	Endocardial Cushion Defects	3.2%
652	neurofibroma	3.2%
653	Myocardial bridging	3.2%
654	Gait Apraxia	3.2%
655	Aorticopulmonary Septal Defect	3.2%
656	Sciatica	3.2%
657	Myositis	3.1%
658	Optic Atrophy	3.1%
659	Optic Neuritis	3.1%
660	Papilledema	3.1%
661	Strabismus	3.1%
662	Tolosa-Hunt Syndrome	3.1%
663	Isaacs syndrome	3.1%
664	Arsenic Poisoning	3.1%
665	Myotonic Disorders	3.1%
666	Myasthenic Syndromes, Congenital	3.1%
667	Neuroaspergillosis	3.1%
668	Acromegaly	3.1%
669	Diabetic Neuropathies	3%
670	Facial Neuralgia	3%
671	Diabetic Amyotrophy	3%
672	Diabetic Autonomic Neuropathy	3%
673	Sleep Talking	3%
674	Manganese Poisoning	3%
675	Sleep Disorders, Intrinsic	3%
676	Orthostatic intolerance	3%
677	Anosmia	3%
678	Ataxia	3%
679	Athetosis	3%
680	Catalepsy	3%
681	Dystonia	3%
682	Hemiplegia	3%
683	Locked-In Syndrome	3%
684	Meningeal Neoplasms	3%
685	Meningomyelocele	3%
686	Muscle Hypertonia	3%
687	Muscle hypotonia	3%
688	Myoclonus	3%
689	Myotonia	3%
690	Neuralgia	3%
691	Paraplegia	3%
692	Pseudobulbar Palsy	3%
693	Quadriplegia	3%
694	Spasm	3%
695	Spastic Paraplegia	3%
696	Status Epilepticus	3%
697	Taste Disorders	3%
698	Tremor	3%
699	Spina Bifida	3%
700	Monoplegia	3%
701	Hypokinesia	3%
702	Paraparesis	3%
703	Bradykinesia	3%
704	Waxy flexibility	3%
705	Action Tremor	3%
706	Resting Tremor	3%
707	Dysosmia	3%
708	Quadriparesis	3%
709	Mercury Poisoning, Nervous System	3%
710	Olfaction Disorders	3%
711	Myokymia	3%
712	Lead Poisoning, Nervous System	3%
713	Vestibular Neuronitis	3%
714	Somatosensory Disorders	3%
715	Neuropathic pain	3%
716	Hyperkinesia	3%
717	Intention tremor	3%
718	Acoustic Neuroma	3%
719	Amyloid Neuropathies, Familial	3%
720	Romano-Ward Syndrome	2.9%
721	Tendinitis	2.9%
722	Lung Injury	2.9%
723	Tendinopathy	2.9%
724	Foreign-Body Reaction	2.8%
725	Insect Bites and Stings	2.8%
726	Paralysis, Obstetric	2.8%
727	Sunburn	2.8%
728	Tooth Avulsion	2.8%
729	Near Drowning	2.8%
730	Osteoradionecrosis	2.8%
731	Pseudorabies	2.8%
732	Sinus Arrhythmia	2.8%
733	Atrial Fibrillation	2.8%
734	Atrial Flutter	2.8%
735	Edema, Cardiac	2.8%
736	Ventricular Fibrillation	2.8%
737	Ventricular Flutter	2.8%
738	Parasystole	2.8%
739	Paroxysmal atrial fibrillation	2.8%
740	Bradycardia	2.8%
741	Diabetic Cardiomyopathies	2.8%
742	Menkes Kinky Hair Syndrome	2.8%
743	Cardiomyopathy, Alcoholic	2.8%
744	Ectopia Cordis	2.8%
745	Sudden Cardiac Death	2.8%
746	Left Ventricular Hypertrophy	2.8%
747	Right Ventricular Hypertrophy	2.8%
748	Single umbilical artery	2.8%
749	Galactosemias	2.8%
750	Urea Cycle Disorders, Inborn	2.8%
751	Tyrosinemias	2.8%
752	Chagas Cardiomyopathy	2.8%
753	Vision Disorders	2.7%
754	Metamorphopsia	2.7%
755	Visual Impairment	2.7%
756	Williams Syndrome	2.7%
757	Fibromyalgia	2.7%
758	Neurosyphilis	2.7%
759	Facial Hemiatrophy	2.7%
760	Melkersson-Rosenthal Syndrome	2.7%
761	Mitochondrial Myopathies	2.7%
762	Anisocoria	2.7%
763	Confusion	2.7%
764	Facial paralysis	2.7%
765	Lethargy	2.7%
766	Memory Disorders	2.7%
767	Muscle Cramp	2.7%
768	Perceptual Disorders	2.7%
769	Psychomotor Disorders	2.7%
770	Tonic Pupil	2.7%
771	Eosinophilia-Myalgia Syndrome	2.7%
772	Anhedonia	2.7%
773	Disorientation	2.7%
774	Facial Paresis	2.7%
775	Memory Loss	2.7%
776	Hemisensory Neglect	2.7%
777	Dysacusis	2.7%
778	Sleep Bruxism	2.7%
779	Anencephaly	2.7%
780	Meningocele	2.7%
781	Muscular Atrophy	2.7%
782	Respiratory Paralysis	2.7%
783	Encephalocele	2.7%
784	Tetany	2.6%
785	Classical Lissencephalies and Subcortical Band Heterotopias	2.6%
786	Homocystinuria	2.6%
787	Leigh Disease	2.6%
788	Neoplasms, Radiation-Induced	2.5%
789	Uterine Rupture	2.5%
790	Dyspnea, Paroxysmal	2.5%
791	Prolactinoma	2.4%
792	Growth Hormone-Secreting Pituitary Adenoma	2.4%
793	Sciatic Neuropathy	2.4%
794	Ulnar Neuropathies	2.4%
795	Lesion of Sciatic Nerve	2.4%
796	Ulnar Neuritis	2.4%
797	Radial nerve compression	2.4%
798	Radial Tunnel Syndrome	2.4%
799	Peroneal Neuropathies	2.4%
800	Radial Neuropathy	2.4%
801	Median Neuropathy	2.4%
802	Sciatic Nerve Palsy	2.4%
803	Femoral Neuropathy	2.4%
804	Tibial Neuropathy	2.4%
805	Ulnar Nerve Palsy	2.4%
806	Postural Orthostatic Tachycardia Syndrome	2.4%
807	Radial nerve palsy	2.4%
808	Lyme Neuroborreliosis	2.4%
809	Tachycardia, Atrioventricular Nodal Reentry	2.4%
810	Tachycardia, Ectopic Atrial	2.4%
811	Tachycardia, Ectopic Junctional	2.4%
812	Sinus Tachycardia	2.4%
813	Torsades de Pointes	2.4%
814	Accelerated Idioventricular Rhythm	2.4%
815	Truncus Arteriosus, Persistent	2.4%
816	Duane Retraction Syndrome	2.4%
817	Consciousness Disorders	2.4%
818	Mental Retardation	2.4%
819	Muscle Weakness	2.4%
820	Depressed Level of Consciousness	2.4%
821	Mental deficiency	2.4%
822	Intellectual Disability	2.4%
823	Mobius Syndrome	2.4%
824	Bell Palsy	2.4%
825	Catatonia	2.4%
826	Herpes Zoster Oticus	2.4%
827	Familial Periodic Paralysis	2.4%
828	Aphonia	2.4%
829	Sleep Deprivation	2.4%
830	Dysphonia	2.4%
831	Nelson Syndrome	2.3%
832	Waterhouse-Friderichsen Syndrome	2.3%
833	Alexia	2.3%
834	Dyslexia	2.3%
835	Toxoplasmosis, Congenital	2.3%
836	Malaria, Cerebral	2.2%
837	Cardiotoxicity	2.2%
838	Neurocysticercosis	2.2%
839	Leukemia, Radiation-Induced	2.2%
840	Radiation Pneumonitis	2.2%
841	Radiation Fibrosis	2.2%
842	Pseudarthrosis	2.2%
843	Smoke Inhalation Injury	2.2%
844	Aortic Valve Prolapse	2.2%
845	Tricuspid Valve Prolapse	2.2%
846	Optic Atrophy, Hereditary, Leber	2.2%
847	Takotsubo Cardiomyopathy	2.2%
848	Turner Syndrome	2.2%
849	Myalgia	2.1%
850	Neuronal Ceroid-Lipofuscinoses	2.1%
851	Esotropia	2.1%
852	Exotropia	2.1%
853	Sleep Apnea Syndromes	2.1%
854	Polymyositis	2.1%
855	Disorders of Excessive Somnolence	2.1%
856	Sleep Initiation and Maintenance Disorders	2.1%
857	Night Terrors	2.1%
858	Somnambulism	2.1%
859	Trigeminal Nerve Disorder	2.1%
860	Transient Insomnia	2.1%
861	Sleep Paralysis	2.1%
862	Chronic Insomnia	2.1%
863	REM Sleep Behavior Disorder	2.1%
864	Hypersomnia	2.1%
865	Neurofibrosarcoma	2.1%
866	Dermal Sinus	2.1%
867	Dysgeusia	2.1%
868	Formication	2.1%
869	Hyperalgesia	2.1%
870	Hyperesthesia	2.1%
871	Hypesthesia	2.1%
872	Language Disorders	2.1%
873	Numbness	2.1%
874	Paresthesia	2.1%
875	Paraparesis, Spastic	2.1%
876	Spina Bifida Cystica	2.1%
877	Trismus	2.1%
878	Spina Bifida Occulta	2.1%
879	Epilepsia Partialis Continua	2.1%
880	Hypogeusia	2.1%
881	Meningeal Carcinomatosis	2.1%
882	Brown-Sequard Syndrome	2.1%
883	Lissencephaly	2.1%
884	Polymicrogyria	2.1%
885	Pachygyria	2.1%
886	Schizencephaly	2.1%
887	Lockjaw	2.1%
888	Allodynia	2.1%
889	Lead Poisoning, Nervous System, Childhood	2.1%
890	Lead Poisoning, Nervous System, Adult	2.1%
891	Periventricular Nodular Heterotopia	2.1%
892	Ageusia	2.1%
893	Zellweger Syndrome	2.1%
894	Carbamoyl-Phosphate Synthase I Deficiency Disease	2%
895	Abnormalities, Radiation-Induced	2%
896	Aicardi's syndrome	2%
897	Radiation Injuries, Experimental	2%
898	Hoarseness	2%
899	Cockayne Syndrome	1.9%
900	Alcohol Withdrawal Delirium	1.9%
901	Polyradiculopathy	1.9%
902	Granuloma, Foreign-Body	1.9%
903	Enthesopathy	1.9%
904	Uterine Perforation	1.9%
905	Sinus Arrest, Cardiac	1.9%
906	Muscular Dystrophy	1.9%
907	Congenital nystagmus	1.9%
908	Orbital Myositis	1.9%
909	Glycogen storage disease type II	1.8%
910	Diplopia	1.8%
911	Muscle Rigidity	1.8%
912	Muscle Spasticity	1.8%
913	Scotoma	1.8%
914	Photophobia	1.8%
915	Cogwheel Rigidity	1.8%
916	Hemifacial Spasm	1.8%
917	Amaurosis	1.8%
918	Blindness	1.8%
919	Nuchal Rigidity	1.8%
920	Pyomyositis	1.8%
921	Agnosia	1.8%
922	Apraxias	1.8%
923	Hallucinations	1.8%
924	Hemianopsia	1.8%
925	Hyperacusis	1.8%
926	Tinnitus	1.8%
927	Visual Agnosia	1.8%
928	Anosognosia	1.8%
929	Wernicke-Korsakoff Syndrome	1.8%
930	Phonophobia	1.8%
931	Hearing Loss	1.8%
932	Sarcopenia	1.8%
933	Holoprosencephaly	1.8%
934	Amnesia	1.6%
935	Delirium	1.6%
936	Dissociative Amnesia	1.6%
937	Color blindness	1.6%
938	Global Amnesia	1.6%
939	Cri-du-Chat Syndrome	1.6%
940	Down Syndrome	1.6%
941	Trisomy 21	1.6%
942	POEMS Syndrome	1.6%
943	Meningioma	1.6%
944	Microcephaly	1.6%
945	Macrocephaly	1.6%
946	Hypokalemic periodic paralysis	1.6%
947	Sleep Apnea, Obstructive	1.6%
948	Sleep Apnea, Central	1.6%
949	Narcolepsy	1.6%
950	Trigeminal Neuralgia	1.6%
951	Kleine-Levin Syndrome	1.6%
952	Porencephaly	1.6%
953	Agraphia	1.6%
954	Anomia	1.6%
955	Cluttering	1.6%
956	Language Development Disorders	1.6%
957	Speech Disorders	1.6%
958	Syncope	1.6%
959	Stupor	1.6%
960	Dysgraphia	1.6%
961	Presyncope	1.6%
962	Dyslalia	1.6%
963	Kartagener Syndrome	1.6%
964	Gaucher Disease	1.5%
965	Prader-Willi Syndrome	1.5%
966	Phantom pain	1.5%
967	Phantom Limb Pain	1.5%
968	Welander Distal Myopathy	1.4%
969	Amaurosis Fugax	1.4%
970	Blindness, Cortical	1.4%
971	Dyscalculia	1.4%
972	Rett Syndrome	1.4%
973	Deafness	1.4%
974	Hearing Loss, Sudden	1.4%
975	Gerstmann Syndrome	1.4%
976	Hearing Loss, Bilateral	1.4%
977	Hearing Loss, High-Frequency	1.4%
978	Hearing Loss, Mixed Conductive-Sensorineural	1.4%
979	Prosopagnosia	1.4%
980	Apraxia, Ideomotor	1.4%
981	Charles Bonnet Syndrome	1.4%
982	Hearing Loss, Unilateral	1.4%
983	Complete Hearing Loss	1.4%
984	Alien Hand Syndrome	1.4%
985	Deaf Mutism	1.4%
986	Cataplexy	1.4%
987	Aphasia	1.4%
988	Articulation Disorders	1.4%
989	Echolalia	1.4%
990	Stuttering	1.4%
991	Dysphasia	1.4%
992	Tay-Sachs Disease	1.3%
993	Dermatomyositis	1.3%
994	Niemann-Pick Disease, Type C	1.3%
995	Muscular Dystrophy, Duchenne	1.3%
996	Dysarthria	1.3%
997	Retrograde amnesia	1.3%
998	Amnesia, Anterograde	1.3%
999	Rubinstein-Taybi Syndrome	1.2%
1000	Mutism	1.2%
1001	Selective Mutism	1.2%
1002	Fragile X Syndrome	1.1%
1003	Alexia, Pure	1.1%
1004	Mucopolysaccharidosis II	0.9%

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