MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

AIDS related complex

(UMLS:C0001857)

Definition:: A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.
UMLS ID:: C0001857
MeSH ID:: D000386

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.782.815.616.400.080|C02.800.801.400.080|C02.839.080

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.673.480.080

Synonym(s)

AIDS related complex

AIDS RELATED COMPLEX

AIDS-like syndrome

AIDS-related complex

ARC

ARC - Acquired immunodeficiency syndrome-related complex

Acquired immune deficiency syndrome-related complex

Acquired immunodeficiency syndrome-like syndrome

aids-related complex

10.

aids-related complex (ARC)

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Stavudine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Acquired Immunodeficiency Syndrome	56%
2	HIV Seropositivity	47.7%
3	HIV Wasting Syndrome	37.2%
4	AIDS Dementia Complex	37%
5	AIDS-Associated Nephropathy	37%
6	HIV-Associated Lipodystrophy Syndrome	33.2%
7	AIDS-Related Opportunistic Infections	30.8%
8	Simian Acquired Immunodeficiency Syndrome	30.1%
9	Rift Valley Fever	22.8%
10	Condylomata Acuminata	22.3%
11	Dengue Fever	21.7%
12	Yellow Fever	21.7%
13	Murine Acquired Immunodeficiency Syndrome	21.3%
14	Hepatitis E	21.2%
15	Hemorrhagic Fever, Crimean	21.1%
16	Subacute Sclerosing Panencephalitis	21.1%
17	Arbovirus Infections	20.4%
18	Warts	19.6%
19	Phlebotomus Fever	19%
20	Leukoencephalopathy, Progressive Multifocal	19%
21	Hemorrhagic Fever, American	18.3%
22	Lassa Fever	18.3%
23	Orthomyxoviridae Infections	17.8%
24	Picornaviridae Infections	17.8%
25	Reoviridae Infections	17.8%
26	Hepatitis, Viral, Human	16.9%
27	Viremia	16.8%
28	HTLV-I Infections	16.3%
29	Epstein-Barr Virus Infections	16.2%
30	Hepatitis C	16.2%
31	West Nile Fever	16.2%
32	Zika Virus Infection	16.2%
33	Genital Herpes	15.9%
34	Hemorrhagic Fever with Renal Syndrome	15.4%
35	Opportunistic Infections	15%
36	Hepatitis, Viral, Animal	14.5%
37	Pneumonia, Viral	14.4%
38	Hepatitis B	13.8%
39	Molluscum Contagiosum	13.8%
40	Hepatitis A	13.8%
41	Epidermodysplasia Verruciformis	13%
42	Chronic Fatigue Syndrome	12.8%
43	Pseudorabies	12.4%
44	Erythema Infectiosum	12.1%
45	Herpesviridae Infections	11.8%
46	Polyomavirus Infections	11.8%
47	Herpes Zoster Ophthalmicus	11.7%
48	Enterovirus Infections	11%
49	Flavivirus Infections	11%
50	Paramyxoviridae Infections	11%
51	Cardiovirus Infections	11%
52	Rhabdoviridae Infections	11%
53	Keratitis, Herpetic	10.9%
54	Cytomegalovirus Retinitis	10.9%
55	Exanthema Subitum	10.8%
56	Lymphopenia	10%
57	Herpangina	9.8%
58	Foot-and-Mouth Disease	9.5%
59	Hepatitis C, Chronic	9.4%
60	Eczema Herpeticum	9.4%
61	Common Cold	9.2%
62	Influenza	9.2%
63	Catarrh	9.2%
64	AIDS related complex	9.1%
65	Sexually Transmitted Diseases	8.9%
66	Retroviridae Infections	8.8%
67	Agammaglobulinemia	8.6%
68	Superinfection	8.5%
69	Herpes Labialis	8.2%
70	Hepatitis B, Chronic	8.2%
71	Burkitt Lymphoma	8%
72	Cytomegalovirus Infections	7.6%
73	Smallpox	7.6%
74	Varicella Zoster Virus Infection	7.6%
75	Coxsackievirus Infections	7.6%
76	Rubella	7.6%
77	Coronavirus Infections	7.6%
78	Nipah Virus Infection	7.6%
79	Hydrophobia	7.6%
80	HIV Infections	7.4%
81	Autoimmune Diseases	6.9%
82	Hypersensitivity	6.9%
83	Immunoproliferative Disorders	6.9%
84	Immune reconstitution syndrome	6.9%
85	Immune Reconstitution Inflammatory Syndrome	6.9%
86	Job Syndrome	6.6%
87	Porcine Reproductive and Respiratory Syndrome	6.4%
88	Measles	5.9%
89	Pleurodynia, Epidemic	5.9%
90	Respiratory Syncytial Virus Infections	5.9%
91	Transfusion Reaction	5.8%
92	Hypotensive Transfusion Reaction	5.8%
93	Chronic granulomatous disease	5.7%
94	Chickenpox	5.6%
95	Vesicular Stomatitis	5.6%
96	Ataxia Telangiectasia	5.5%
97	Infectious Mononucleosis	5.2%
98	Gastroenteritis, Transmissible, of Swine	5%
99	Severe Acute Respiratory Syndrome	5%
100	Mumps	4.9%
101	Bell Palsy	4.8%
102	Glomerulonephritis, Membranoproliferative	4.8%
103	Poliomyelitis	4.8%
104	Autoimmune Lymphoproliferative Syndrome	4.2%
105	Immune Complex Diseases	4%
106	Antiphospholipid Syndrome	4%
107	Latex allergy	4%
108	Wiskott-Aldrich Syndrome	4%
109	Thrombocytopenic purpura	3.7%
110	Autoimmune thrombocytopenia	3.6%
111	Immune thrombocytopenic purpura	3.6%
112	Environmental Illness	3.5%
113	Lupus Erythematosus, Systemic	3.4%
114	Lymphoproliferative Disorders	3.4%
115	Overlap syndrome	3.4%
116	Addison Disease	3.4%
117	Paraproteinemias	3.4%
118	Pemphigus	3.4%
119	Autoimmune thyroiditis	3.4%
120	Primary Adrenal Insufficiency	3.4%
121	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.3%
122	Autoimmune hepatitis	3.3%
123	Primary amyloidosis	3.3%
124	Monoclonal Gammopathy of Undetermined Significance	3.3%
125	Asthma, Aspirin-Induced	3%
126	Herpes Zoster Oticus	2.9%
127	Hypergammaglobulinemia	2.9%
128	Latent Autoimmune Diabetes in Adults	2.9%
129	Dermatitis Herpetiformis	2.9%
130	Kounis Syndrome	2.9%
131	Serum Sickness	2.9%
132	Transfusion-Related Acute Lung Injury	2.9%
133	anaphylaxis	2.7%
134	Food Allergy	2.7%
135	Anaphylactic shock	2.7%
136	Multiple Myeloma	2.6%
137	Rheumatoid Arthritis	2.5%
138	Juvenile arthritis	2.5%
139	Graves Disease	2.5%
140	Anti-Glomerular Basement Membrane Disease	2.5%
141	Respiratory Hypersensitivity	2.3%
142	Sick Building Syndrome	2.2%
143	Multiple Chemical Sensitivity	2.2%
144	Sezary Syndrome	2.2%
145	Plasmacytoma	2.2%
146	Tumor Lysis Syndrome	2.2%
147	Urticaria	2.2%
148	Vasculitis, Leukocytoclastic, Cutaneous	2.2%
149	Kernicterus	2%
150	Milk Allergy	2%
151	Schnitzler Syndrome	2%
152	Wheat Hypersensitivity	2%
153	Myasthenia Gravis, Autoimmune, Experimental	2%
154	Lymphoma	1.9%
155	Myasthenia Gravis	1.9%
156	Uveomeningoencephalitic Syndrome	1.9%
157	Mastocytosis	1.9%
158	Drug Eruptions	1.9%
159	Heavy Chain Disease	1.9%
160	Granulomatosis with polyangiitis	1.9%
161	Dermatitis, Allergic Contact	1.9%
162	Hydrops Fetalis	1.8%
163	Stiff-Person Syndrome	1.7%
164	Polyradiculoneuropathy	1.7%
165	Polyradiculoneuritis	1.7%
166	Cryoglobulinemia	1.6%
167	Felty Syndrome	1.6%
168	POEMS Syndrome	1.6%
169	Lupus Nephritis	1.6%
170	Mastocytosis, Systemic	1.6%
171	Lupus Vasculitis, Central Nervous System	1.5%
172	Neuromyelitis Optica	1.5%
173	Leukoencephalitis, Acute Hemorrhagic	1.5%
174	Vasculitis, Central Nervous System	1.5%
175	Dermatitis, Atopic	1.5%
176	Rheumatoid Vasculitis	1.5%
177	Angioedema	1.4%
178	Multiple Sclerosis	1.4%
179	Hodgkin Disease	1.4%
180	Leukemia, Plasma Cell	1.4%
181	Lymphoma, Non-Hodgkin	1.4%
182	Leukemia, T-Cell	1.4%
183	Acute Generalized Exanthematous Pustulosis	1.4%
184	Leukemia, B-Cell	1.4%
185	Lambert-Eaton Myasthenic Syndrome	1.3%
186	Waldenstrom Macroglobulinemia	1.3%
187	Sicca Syndrome	1.3%
188	Sjogren's Syndrome	1.3%
189	Asthma	1.3%
190	Composite Lymphoma	1.2%
191	Encephalomyelitis, Acute Disseminated	1.2%
192	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1.2%
193	Erythema Nodosum	1.2%
194	Neuritis, Autoimmune, Experimental	1.2%
195	Dermatitis, Photoallergic	1.2%
196	Lymphangioleiomyomatosis	1.2%
197	Asthma, Exercise-Induced	1.2%
198	Status Asthmaticus	1.2%
199	Multiple Sclerosis, Chronic Progressive	1.2%
200	Multiple Sclerosis, Relapsing-Remitting	1.2%
201	Lymphoma, Follicular	1.2%
202	T-Cell Lymphoma	1.2%
203	Mantle cell lymphoma	1.2%
204	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.2%
205	Leukemia, Large Granular Lymphocytic	1.2%
206	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.2%
207	Aspergillosis, Allergic Bronchopulmonary	1.1%
208	Guillain-Barre Syndrome	1.1%
209	Asthma, Occupational	1.1%
210	Hereditary Angioedema Type III	1%
211	Hereditary Angioedema Types I and II	1%
212	Lymphoma, T-Cell, Cutaneous	1%
213	Lymphoma, AIDS-Related	1%
214	Enteropathy-Associated T-Cell Lymphoma	1%
215	Primary Effusion Lymphoma	1%
216	Farmer's Lung	1%
217	Angioedemas, Hereditary	1%
218	Hay fever	1%
219	Rhinitis, Allergic, Perennial	1%
220	Mycosis Fungoides	1%
221	Lymphomatoid Papulosis	1%
222	Plasmablastic lymphoma	1%
223	Toxic Epidermal Necrolysis	1%
224	Stevens-Johnson Syndrome	1%
225	Lymphomatoid Granulomatosis	0.9%
226	Giant Cell Arteritis	0.9%
227	Temporal Arteritis	0.9%
228	Myelitis, Transverse	0.8%
229	Miller Fisher Syndrome	0.7%

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