MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Atrial Premature Complexes

(UMLS:C0033036)

Definition:: A type of cardiac arrhythmia with premature atrial contractions or beats caused by signals originating from ectopic atrial sites. The ectopic signals may or may not conduct to the HEART VENTRICLES. Atrial premature complexes are characterized by premature P waves on ECG which are different in configuration from the P waves generated by the normal pacemaker complex in the SINOATRIAL NODE.
UMLS ID:: C0033036
MeSH ID:: D018880

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.067.325.250|C14.280.123.375.250

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.073.325.050

Synonym(s)

Atrial Premature Complexes

APC

Atrial Ectopic Beats

Atrial Premature Complex (APC)

Atrial ectopic

Atrial ectopic beats

Atrial extrasystoles

Atrial premature beats

Atrial premature complex

10.

Atrial premature contractions

11.

Atrial premature depolarisation

12.

Atrial premature depolarization

13.

Atrial premature systoles

14.

Ectopic atrial beats

15.

Ectopic atrial beats, NOS

16.

Ectopic supraventricular rhythms

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Albuterol	2462383	CTD
2	Digitoxin	2447325	CTD
3	Digoxin	66122	CTD
4	Disopyramide	2564745	CTD
5	Dobutamine	8319327	CTD
6	Naloxone	574740	CTD
7	Ritodrine	2450324	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Heart Block	44.3%
2	Tachycardia	44.3%
3	Tachyarrhythmia	44.3%
4	Long QT Syndrome	37.9%
5	Sick Sinus Syndrome	35.5%
6	Sinus Arrhythmia	33.3%
7	Atrial Fibrillation	33.3%
8	Atrial Flutter	33.3%
9	Ventricular Fibrillation	33.3%
10	Ventricular Flutter	33.3%
11	Parasystole	33.3%
12	Paroxysmal atrial fibrillation	33.3%
13	Bradycardia	33.3%
14	Adams-Stokes Syndrome	29%
15	Atrioventricular Block	29%
16	Bundle-Branch Block	29%
17	Sinoatrial Block	29%
18	Tachycardia, Paroxysmal	29%
19	Supraventricular tachycardia	29%
20	Tachycardia, Ventricular	29%
21	Tachycardia, Reciprocating	29%
22	Myocardial Ischemia	26.8%
23	Postpericardiotomy Syndrome	25.8%
24	Lown-Ganong-Levine Syndrome	25.8%
25	Romano-Ward Syndrome	24.8%
26	Cardiac Tamponade	24.8%
27	Endocarditis	24.8%
28	Cardiac Arrest	24.8%
29	Heart failure	24.8%
30	Pericardial effusion	24.8%
31	Pericarditis	24.8%
32	Pneumopericardium	24.8%
33	Cor pulmonale	24.8%
34	Ventricular Outflow Obstruction	24.8%
35	Ventricular Dysfunction	24.8%
36	Cardiomyopathies	24.8%
37	Pleuropericarditis	24.8%
38	Aortic Valve Stenosis	23.5%
39	Cardiomyopathy, Dilated	23.5%
40	Pulmonary Valve Stenosis	23.5%
41	Cardiac Output, High	23.5%
42	Myocardial Stunning	23.5%
43	Low Cardiac Output Syndrome	23.5%
44	Myocardial Reperfusion Injury	22.1%
45	Sinus Arrest, Cardiac	21.9%
46	Cardiomegaly	21.9%
47	Cardiac Hypertrophy	21.9%
48	Tachycardia, Atrioventricular Nodal Reentry	21.6%
49	Tachycardia, Ectopic Atrial	21.6%
50	Tachycardia, Ectopic Junctional	21.6%
51	Sinus Tachycardia	21.6%
52	Torsades de Pointes	21.6%
53	Accelerated Idioventricular Rhythm	21.6%
54	Wolff-Parkinson-White Syndrome	21.5%
55	Rheumatic Heart Disease	19.7%
56	Tricuspid Atresia	19.6%
57	Arrhythmogenic Right Ventricular Dysplasia	19.6%
58	Hypertrophic Cardiomyopathy	17.5%
59	Hypertrophic obstructive cardiomyopathy	17.5%
60	Coronary heart disease	15.7%
61	Myocardial Infarction	15.7%
62	Acute Coronary Syndrome	15.7%
63	Sudden Cardiac Death	15.6%
64	Supravalvular aortic stenosis	15.5%
65	Vascular Diseases	15.4%
66	Aortic Valve Insufficiency	14.6%
67	Restrictive cardiomyopathy	14.6%
68	Endocardial Fibroelastosis	14.6%
69	Heart Rupture, Post-Infarction	14.6%
70	Mitral Valve Insufficiency	14.6%
71	Mitral Valve Stenosis	14.6%
72	Myocarditis	14.6%
73	Pericarditis, Constrictive	14.6%
74	Pulmonary Valve Insufficiency	14.6%
75	Tricuspid Valve Insufficiency	14.6%
76	Tricuspid Valve Stenosis	14.6%
77	Ventricular Dysfunction, Left	14.6%
78	Right Ventricular Dysfunction	14.6%
79	Endomyocardial Fibrosis	14.6%
80	Carditis	14.6%
81	Heart Failure, Systolic	14.6%
82	Heart Failure, Diastolic	14.6%
83	Carcinoid Heart Disease	13.8%
84	Angina Pectoris	13.8%
85	Edema, Cardiac	13.7%
86	Shock, Cardiogenic	13.5%
87	Polydipsia	13.4%
88	Bacterial Endocarditis	13.4%
89	Kounis Syndrome	13.3%
90	Aortic coarctation	13%
91	Cor Triatriatum	13%
92	Coronary Vessel Anomalies	13%
93	Patent ductus arteriosus	13%
94	Ebstein Anomaly	13%
95	Heart Septal Defects	13%
96	Tetralogy of Fallot	13%
97	Transposition of Great Vessels	13%
98	Hypoplastic Left Heart Syndrome	13%
99	Left Ventricular Hypertrophy	13%
100	Right Ventricular Hypertrophy	13%
101	Reperfusion Injury	12.6%
102	Vasoplegia	12.6%
103	Pregnancy Complications, Cardiovascular	12.4%
104	Cardiovascular Abnormalities	12.4%
105	Ascites	12.4%
106	Fibrosis	12.4%
107	Gliosis	12.4%
108	Growth Disorders	12.4%
109	Hemorrhage	12.4%
110	Hyperbilirubinemia	12.4%
111	Hyperplasia	12.4%
112	Hypomenorrhea	12.4%
113	Inflammation	12.4%
114	Intraoperative Complications	12.4%
115	Ischemia	12.4%
116	Lithiasis	12.4%
117	Malacoplakia	12.4%
118	Menstruation Disturbances	12.4%
119	Metaplasia	12.4%
120	Nerve Degeneration	12.4%
121	Ochronosis	12.4%
122	Polymenorrhea	12.4%
123	Postoperative Complications	12.4%
124	Sclerosis	12.4%
125	Shock	12.4%
126	Ulcer	12.4%
127	Hyperammonemia	12.4%
128	Hyperamylasemia	12.4%
129	Teratogenesis	12.4%
130	Cardiac Death	12.4%
131	Hypovolemia	12.4%
132	Hyperuricemia	12.4%
133	Leukoaraiosis	12.4%
134	Dysbacteriosis	12.4%
135	Delayed Graft Function	12.4%
136	Cirrhosis	12.4%
137	Neointima	12.4%
138	Dysbiosis	12.4%
139	Coronary Aneurysm	11.9%
140	Infarction	11.8%
141	Postoperative Hemorrhage	11.8%
142	Shock, Hemorrhagic	11.8%
143	Systemic Inflammatory Response Syndrome	11.8%
144	Diabetic Cardiomyopathies	11.8%
145	Cardiomyopathy, Alcoholic	11.7%
146	Chagas Cardiomyopathy	11.7%
147	Vascular Remodeling	11.3%
148	Dextrocardia	11.2%
149	Dyspnea, Paroxysmal	10.9%
150	Coronary Thrombosis	10.8%
151	Coronary Artery Disease	10.8%
152	Extravasation of Diagnostic and Therapeutic Materials	10.3%
153	Neoplastic Processes	10.3%
154	Coronary Occlusion	10.3%
155	Microvascular Angina	10.3%
156	Coronary Stenosis	10.3%
157	ST segment elevation myocardial infarction	10.3%
158	Necrosis	10.1%
159	Granulomatosis, Orofacial	10.1%
160	Pigmentation Disorders	10.1%
161	Respiratory Aspiration	10.1%
162	Acantholysis	9.9%
163	Chromosome Aberrations	9.9%
164	Dehydration	9.9%
165	Granuloma	9.9%
166	Leukocytosis	9.9%
167	Pleocytosis	9.9%
168	Aortic Valve Prolapse	9.7%
169	Tricuspid Valve Prolapse	9.7%
170	Takotsubo Cardiomyopathy	9.7%
171	Angina, Unstable	9.2%
172	Noonan Syndrome	8.8%
173	Aortopulmonary Septal Defect	8.6%
174	Double Outlet Right Ventricle	8.6%
175	Endocardial Cushion Defects	8.6%
176	Myocardial bridging	8.6%
177	Aorticopulmonary Septal Defect	8.6%
178	Genomic Instability	8.6%
179	Chromosomal Instability	8.5%
180	No-Reflow Phenomenon	8.4%
181	Aneurysm	8.3%
182	Angiomatosis	8.3%
183	Aortic Diseases	8.3%
184	Arterial Occlusive Diseases	8.3%
185	Hyperemia	8.3%
186	Hypotension	8.3%
187	Superior Vena Cava Syndrome	8.3%
188	Telangiectasis	8.3%
189	Vasculitis	8.3%
190	Venous Insufficiency	8.3%
191	Peripheral Vascular Diseases	8.3%
192	Embolism and Thrombosis	8.3%
193	Angiodysplasia	8.3%
194	Capillary Leak Syndrome	8.3%
195	Prehypertension	8.3%
196	Azotemia	8.2%
197	Muscle Weakness	8.1%
198	Menorrhagia	8.1%
199	Marfan Syndrome	8%
200	Arteriovenous fistula	7.9%
201	Aortic Aneurysm	7.8%
202	Aortitis	7.8%
203	Leriche Syndrome	7.8%
204	Periphlebitis	7.8%
205	Phlebitis	7.8%
206	Thromboangiitis Obliterans	7.8%
207	Incisional hernia	7.8%
208	jaundice	7.8%
209	Primary Graft Dysfunction	7.8%
210	Sudden infant death syndrome	7.7%
211	Embolism, Amniotic Fluid	7.7%
212	Signs and Symptoms	7.7%
213	Pathological Conditions, Anatomical	7.7%
214	Coronary Restenosis	7.7%
215	Acute Disease	7.3%
216	Acute-Phase Reaction	7.3%
217	Amenorrhea	7.3%
218	Chronic disease	7.3%
219	Critical Illness	7.3%
220	Sudden death	7.3%
221	Subacute Bacterial Endocarditis	7.3%
222	Fat necrosis	7.3%
223	Gangrene	7.3%
224	Graft Occlusion, Vascular	7.3%
225	Granuloma, Plasma Cell	7.3%
226	Hematoma	7.3%
227	Iatrogenic Disease	7.3%
228	Multiple Organ Failure	7.3%
229	Oligomenorrhea	7.3%
230	Premenstrual syndrome	7.3%
231	Recurrence	7.3%
232	Retrograde Degeneration	7.3%
233	Retroperitoneal fibrosis	7.3%
234	Serositis	7.3%
235	Subcutaneous Emphysema	7.3%
236	Surgical Wound Dehiscence	7.3%
237	Syndrome	7.3%
238	Wallerian Degeneration	7.3%
239	Pyogenic granuloma	7.3%
240	Exsanguination	7.3%
241	Disease Progression	7.3%
242	Seroma	7.3%
243	Premenstrual Tension	7.3%
244	Delayed Emergence from Anesthesia	7.3%
245	Infant Death	7.3%
246	Anastomotic Leak	7.3%
247	Intraoperative Awareness	7.3%
248	Cardiotoxicity	7.2%
249	Retinal Vein Occlusion	7.2%
250	Pain, Postoperative	7.1%
251	Postoperative Nausea and Vomiting	7%
252	Angina Pectoris, Variant	7%
253	Vascular System Injuries	6.9%
254	Dysmenorrhea	6.8%
255	Failed Back Surgery Syndrome	6.8%
256	Eye Hemorrhage	6.8%
257	Compartment syndromes	6.7%
258	Hepatic Veno-Occlusive Disease	6.7%
259	Peliosis Hepatis	6.7%
260	Varicocele	6.7%
261	Hemoptysis	6.6%
262	Cerebrovascular Disorders	6.6%
263	Diabetic Angiopathies	6.6%
264	Splenic Infarction	6.6%
265	Cerebrovascular Insufficiency	6.6%
266	Vascular Neoplasms	6.6%
267	Spinal Cord Vascular Diseases	6.6%
268	Hemorrhoids	6.6%
269	Thoracic Outlet Syndrome	6.6%
270	Ecchymosis	6.6%
271	Petechiae	6.6%
272	Purpura	6.6%
273	Malignant Atrophic Papulosis	6.6%
274	Shwartzman Phenomenon	6.5%
275	May-Thurner Syndrome	6.5%
276	Postphlebitic Syndrome	6.5%
277	Atrial Premature Complexes	6.5%
278	Truncus Arteriosus, Persistent	6.4%
279	Asphyxia	6.1%
280	Granuloma, Respiratory Tract	6.1%
281	Shock, Traumatic	6.1%
282	Scimitar Syndrome	6%
283	Disease susceptibility	6%
284	Fetal Death	6%
285	Foreign-Body Reaction	6%
286	Gastrointestinal Hemorrhage	6%
287	Hemarthrosis	6%
288	Hemoperitoneum	6%
289	Hemothorax	6%
290	Neoplasm Invasiveness	6%
291	Neoplasm Metastasis	6%
292	Neoplasm Recurrence, Local	6%
293	Prosthesis Failure	6%
294	Injection Site Reaction	6%
295	Retrobulbar Hemorrhage	6%
296	Aseptic Necrosis of Bone	6%
297	Peritoneal Fibrosis	6%
298	Carcinogenesis	6%
299	Neurogenic Inflammation	6%
300	Perinatal death	6%
301	Infusion site reaction	6%
302	Nephrogenic Fibrosing Dermopathy	6%
303	Corneal Endothelial Cell Loss	6%
304	Encapsulating Peritoneal Sclerosis	6%
305	Suppuration	6%
306	Nephrogenic Systemic Fibrosis	6%
307	Metastasis	6%
308	Intermittent Claudication	5.9%
309	Thrombophlebitis	5.9%
310	Dental Pulp Necrosis	5.9%
311	Granuloma, Foreign-Body	5.9%
312	Mediastinal Emphysema	5.9%
313	Surgical Wound Infection	5.9%
314	Facies	5.9%
315	Embryo Loss	5.9%
316	Afferent Loop Syndrome	5.8%
317	Sex Chromosome Aberrations	5.8%
318	Short Bowel Syndrome	5.8%
319	Uterine hemorrhage	5.8%
320	Epistaxis	5.7%
321	Hand-Arm Vibration Syndrome	5.7%
322	Purpura, Hyperglobulinemic	5.7%
323	Endotoxic shock	5.7%
324	Septic Shock	5.7%
325	Toxic Shock Syndrome	5.7%
326	Aortic Rupture	5.6%
327	Optic Neuropathy, Ischemic	5.6%
328	Anterior Ischemic Optic Neuropathy	5.6%
329	Mesenteric vascular insufficiency	5.6%
330	Chromosome Fragility	5.5%
331	Blue Toe Syndrome	5.5%
332	Angioedema	5.5%
333	Colitis, Ischemic	5.4%
334	Intracranial Embolism and Thrombosis	5.4%
335	Carotid Stenosis	5.4%
336	Intracranial Aneurysm	5.4%
337	Subarachnoid Hemorrhage	5.4%
338	Cerebral Hemorrhage	5.4%
339	Hematoma, Subdural	5.4%
340	Hematoma, Epidural, Cranial	5.4%
341	Moyamoya Disease	5.2%
342	Jaundice, Obstructive	5.2%
343	Aortic Aneurysm, Abdominal	5.2%
344	Aortic Aneurysm, Thoracic	5.2%
345	Drowning	5.1%
346	Carotid Artery Thrombosis	5%
347	Fetal Growth Retardation	5%
348	DNA Degradation, Necrotic	5%
349	Vasculitis, Central Nervous System	5%
350	Aneuploidy	4.9%
351	Polyploidy	4.9%
352	Microsatellite Instability	4.9%
353	Livedo Reticularis	4.9%
354	Cicatrix	4.9%
355	Hematuria	4.9%
356	Granuloma Annulare	4.9%
357	Chromosome Breakage	4.9%
358	Aneurysm, Dissecting	4.9%
359	Arteriosclerosis	4.9%
360	Arteritis	4.9%
361	Embolism	4.9%
362	Erythromelalgia	4.9%
363	Fibromuscular Dysplasia	4.9%
364	Malignant Hypertension	4.9%
365	Raynaud Disease	4.9%
366	Thromboembolism	4.9%
367	Thrombosis	4.9%
368	Essential Hypertension	4.9%
369	Aneurysm, Ruptured	4.9%
370	Iliac Aneurysm	4.9%
371	Pulmonary artery stenosis	4.9%
372	White Coat Hypertension	4.9%
373	Systemic Vasculitis	4.9%
374	Embolus	4.9%
375	Brain Death	4.9%
376	Tissue Adhesions	4.8%
377	Trisomy	4.8%
378	Hematoma, Epidural, Spinal	4.8%
379	Turner Syndrome	4.8%
380	Kearns-Sayre syndrome	4.8%
381	Hematemesis	4.3%
382	Polyarteritis Nodosa	4.3%
383	Takayasu Arteritis	4.3%
384	Purpura Fulminans	4.3%
385	Intracranial Arteriosclerosis	4.3%
386	Cerebral Atherosclerosis	4.3%
387	Cerebral Arteriosclerosis	4.3%
388	Giant Cell Epulis	4.3%
389	Williams Syndrome	4.2%
390	Micronuclei, Chromosome-Defective	4.1%
391	Asthenia	4.1%
392	Body Temperature Changes	4.1%
393	Calculi	4.1%
394	Cyanosis	4.1%
395	Edema	4.1%
396	Failure to Thrive	4.1%
397	Fatigue	4.1%
398	Feminization	4.1%
399	Fetal Distress	4.1%
400	Hernia	4.1%
401	Hypertrophy	4.1%
402	Motion Sickness	4.1%
403	Nails, Malformed	4.1%
404	polyps	4.1%
405	Rupture, Spontaneous	4.1%
406	Signs and Symptoms, Digestive	4.1%
407	Signs and Symptoms, Respiratory	4.1%
408	Skin Manifestations	4.1%
409	Chills	4.1%
410	Lassitude	4.1%
411	Enterocele	4.1%
412	Atheroma	4.1%
413	Pseudophakia	4.1%
414	Urological Manifestations	4.1%
415	Stenosis	4.1%
416	Facial asymmetry	4.1%
417	Mobility Limitation	4.1%
418	Somnolence	4.1%
419	Plaque, Amyloid	4.1%
420	Plaque, Atherosclerotic	4.1%
421	Basal Ganglia Hemorrhage	4.1%
422	Hematoma, Subdural, Intracranial	4.1%
423	Hematoma, Subdural, Chronic	4.1%
424	Hematoma, Subdural, Acute	4.1%
425	Retinal Artery Occlusion	4%
426	Retinal Vasculitis	4%
427	Hypertensive Retinopathy	4%
428	Cross Infection	3.9%
429	Hyphema	3.9%
430	Retinal Neovascularization	3.9%
431	Septicemia	3.9%
432	Vitreous Hemorrhage	3.9%
433	Sepsis	3.9%
434	Anterior Compartment Syndrome	3.9%
435	Vasculitis, Leukocytoclastic, Cutaneous	3.9%
436	Gastric Antral Vascular Ectasia	3.9%
437	Abdominal Compartment Syndrome	3.9%
438	Abscess	3.9%
439	Carotid Artery Diseases	3.9%
440	Brain Ischemia	3.9%
441	Ectopia Cordis	3.9%
442	Empyema	3.9%
443	Femur Head Necrosis	3.9%
444	Fetal Resorption	3.9%
445	Hypotension, Orthostatic	3.9%
446	Lymphatic Metastasis	3.9%
447	Neoplasms, Unknown Primary	3.9%
448	Peptic Ulcer Hemorrhage	3.9%
449	Cerebrovascular accident	3.9%
450	Varicose Ulcer	3.9%
451	Leukemic Infiltration	3.9%
452	Premenstrual Dysphoric Disorder	3.9%
453	Choroidal Neovascularization	3.9%
454	Vasospasm, Intracranial	3.9%
455	Spinal Cord Ischemia	3.9%
456	Intracranial Arterial Diseases	3.9%
457	Single umbilical artery	3.9%
458	Neoplasm Micrometastasis	3.9%
459	Post-Exercise Hypotension	3.9%
460	Giant Cell Arteritis	3.9%
461	Temporal Arteritis	3.9%
462	Dumping Syndrome	3.9%
463	Cicatrix, Hypertrophic	3.9%
464	Metrorrhagia	3.9%
465	Cerebral Thrombosis	3.7%
466	Intracranial Embolism	3.7%
467	Intracranial Thrombosis	3.7%
468	Subacute Combined Degeneration	3.7%
469	Eosinophilic Granuloma	3.7%
470	Brain Infarction	3.7%
471	Phantom pain	3.6%
472	Phantom Limb Pain	3.6%
473	Hematoma, Subdural, Spinal	3.6%
474	CREST Syndrome	3.6%
475	Kartagener Syndrome	3.5%
476	Cyst	3.4%
477	Eye Manifestations	3.4%
478	Neurologic Manifestations	3.4%
479	Leukoplakia	3.4%
480	Reticulocytosis	3.4%
481	Airway Remodeling	3.4%
482	Retinal Hemorrhage	3.3%
483	Mesenteric Vascular Occlusion	3.3%
484	Mucocutaneous Lymph Node Syndrome	3.3%
485	Thrombocytopenic purpura	3.3%
486	Ventricular Remodeling	3.3%
487	Kernicterus	3.3%
488	Choroid Hemorrhage	3.3%
489	Diabetic Retinopathy	3.3%
490	Melena	3.3%
491	Sturge-Weber Syndrome	3.3%
492	Alopecia	3.3%
493	Androgenetic Alopecia	3.3%
494	Renal Colic	3.3%
495	Putaminal Hemorrhage	3.3%
496	Renal hypertension	3.3%
497	Postpartum Hemorrhage	3.3%
498	Renal Artery Obstruction	3.3%
499	Renal Artery Stenosis	3.3%
500	Abdominal Pain	3.2%
501	Vertebral Artery Dissection	3.2%
502	Gingival Hemorrhage	3.2%
503	Hemangioma, Cavernous	3.2%
504	Keloid	3.2%
505	Basal Ganglia Cerebrovascular Disease	3.2%
506	Monosomy	3.2%
507	Vascular Headaches	3.2%
508	Tetraploidy	3.2%
509	Stillbirth	3.2%
510	Scurvy	3.2%
511	Arteriosclerosis Obliterans	3.2%
512	Atherosclerosis	3.2%
513	Air Embolism	3.2%
514	Endarteritis	3.2%
515	Venous Thrombosis	3.2%
516	Deep Vein Thrombosis	3.2%
517	Venous Thromboembolism	3.2%
518	Subarachnoid Hemorrhage, Traumatic	3.2%
519	Carotid Artery, Internal, Dissection	3.2%
520	Lemierre Syndrome	3.1%
521	Viremia	3%
522	Parasitemia	3%
523	Sinus Thrombosis, Intracranial	2.9%
524	Carotid Artery Injuries	2.9%
525	Cellulitis	2.8%
526	Dural Arteriovenous Fistula	2.8%
527	Infarction, Middle Cerebral Artery	2.8%
528	Infarction, Anterior Cerebral Artery	2.8%
529	Infarction, Posterior Cerebral Artery	2.8%
530	Ischemic contracture	2.8%
531	Angioedemas, Hereditary	2.8%
532	Hypergammaglobulinemia	2.8%
533	Cryoglobulinemia	2.8%
534	Leukomalacia, Periventricular	2.8%
535	Diabetic Foot	2.8%
536	Eye pain	2.7%
537	Cerebral Infarction	2.7%
538	Brain Stem Infarctions	2.7%
539	Diverticulum	2.7%
540	Diverticulosis	2.7%
541	Muscular Atrophy	2.7%
542	Pulmonary Embolism	2.6%
543	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.6%
544	Cerebral Arterial Diseases	2.6%
545	Vertebrobasilar Insufficiency	2.6%
546	Anterior Spinal Artery Syndrome	2.6%
547	Basilar Artery Stenosis	2.6%
548	Vertebral Artery Stenosis	2.6%
549	Intracranial Hemorrhage, Hypertensive	2.6%
550	Transient Cerebral Ischemia	2.6%
551	Granuloma, Laryngeal	2.5%
552	Cavernous Sinus Thrombosis	2.5%
553	Sagittal Sinus Thrombosis	2.5%
554	Bacteremia	2.5%
555	Cell Transformation, Viral	2.5%
556	Anorexia	2.4%
557	Anoxia	2.4%
558	Constipation	2.4%
559	Diarrhea	2.4%
560	Dyspepsia	2.4%
561	Eructation	2.4%
562	Fever	2.4%
563	Flatulence	2.4%
564	Flushing	2.4%
565	Halitosis	2.4%
566	Heartburn	2.4%
567	Diaphragmatic Hernia	2.4%
568	Hiccough	2.4%
569	Hypercalciuria	2.4%
570	Hypercapnia	2.4%
571	Hyperphagia	2.4%
572	Intestinal Polyps	2.4%
573	Nausea	2.4%
574	Pallor	2.4%
575	Psychophysiologic Disorders	2.4%
576	Splenomegaly	2.4%
577	Vomiting	2.4%
578	Fungemia	2.4%
579	Hypocapnia	2.4%
580	Dyschezia	2.4%
581	Hypoxia	2.4%
582	Hyperoxia	2.4%
583	Lower Urinary Tract Symptoms	2.4%
584	Hypoxemia	2.4%
585	Urinoma	2.4%
586	Shy-Drager Syndrome	2.4%
587	Purpura, Thrombotic Thrombocytopenic	2.4%
588	Lateral Medullary Syndrome	2.3%
589	Abdomen, Acute	2.3%
590	Behcet Syndrome	2.2%
591	Waldenstrom Macroglobulinemia	2.2%
592	Multiple Myeloma	2.2%
593	Waterhouse-Friderichsen Syndrome	2.1%
594	Hypertension, Renovascular	2.1%
595	Hypoxia-Ischemia, Brain	2.1%
596	Hereditary Angioedema Type III	2.1%
597	Hereditary Angioedema Types I and II	2.1%
598	Philadelphia Chromosome	2.1%
599	Respiratory Tract Fistula	2%
600	Body Weight	2%
601	Endotoxemia	2%
602	Ataxia Telangiectasia	2%
603	Apnea	2%
604	Cheyne-Stokes Respiration	2%
605	Decerebrate State	2%
606	Dyspnea	2%
607	Hemiparesis	2%
608	Hepatomegaly	2%
609	Hyperventilation	2%
610	Meningism	2%
611	Mouth Breathing	2%
612	Paresis	2%
613	Parovarian Cyst	2%
614	Pruritus	2%
615	Pseudoxanthoma Elasticum	2%
616	Seizures	2%
617	Sensation Disorders	2%
618	Sneezing	2%
619	Spermatocele	2%
620	Erythema	2%
621	Oral Fistula	2%
622	Complex partial seizures	2%
623	Necrolytic Migratory Erythema	2%
624	Tachypnea	2%
625	Monoparesis	2%
626	Cutaneous Fistula	2%
627	Gait Disorders, Neurologic	2%
628	Neuromuscular Manifestations	2%
629	Hepatic Vein Thrombosis	2%
630	Budd-Chiari Syndrome	2%
631	Autoimmune thrombocytopenia	2%
632	Immune thrombocytopenic purpura	2%
633	Mental Fatigue	2%
634	Hirsutism	2%
635	Orthostatic intolerance	2%
636	Hypoventilation	2%
637	Vaginal Fistula	1.9%
638	Rectocele	1.9%
639	Body Weight Changes	1.9%
640	Pulmonary Infarction	1.9%
641	Dementia, Vascular	1.9%
642	Subclavian Steal Syndrome	1.9%
643	Sarcopenia	1.9%
644	Pituitary Apoplexy	1.9%
645	Lupus Vasculitis, Central Nervous System	1.8%
646	Hoarseness	1.8%
647	Sleep Wake Disorders	1.8%
648	Pupil Disorders	1.7%
649	Neurobehavioral Manifestations	1.7%
650	Nasal Polyps	1.7%
651	Pleural Rub	1.7%
652	Rales	1.7%
653	Respiratory Sounds	1.7%
654	Rhonchi	1.7%
655	Stridor	1.7%
656	Wheezing	1.7%
657	Asterixis	1.7%
658	Ballismus	1.7%
659	Vertigo	1.6%
660	Pain	1.6%
661	Ache	1.6%
662	Meningocele	1.6%
663	Oliguria	1.6%
664	Polyuria	1.6%
665	Proteinuria	1.6%
666	Urinary Calculi	1.6%
667	Encephalocele	1.6%
668	Rheumatoid Vasculitis	1.6%
669	Granulomatosis with polyangiitis	1.6%
670	Gait Ataxia	1.6%
671	Back Pain	1.6%
672	Bulimia	1.6%
673	Neck Pain	1.6%
674	Chest Pain	1.6%
675	Colonic Polyps	1.6%
676	Dizziness	1.6%
677	Dysuria	1.6%
678	Facial Pain	1.6%
679	Fever of Unknown Origin	1.6%
680	Flank Pain	1.6%
681	Headache	1.6%
682	Nocturia	1.6%
683	Pain, Intractable	1.6%
684	Pelvic Pain	1.6%
685	Snoring	1.6%
686	Chronic pain	1.6%
687	Lightheadedness	1.6%
688	Pain, Referred	1.6%
689	Prostatism	1.6%
690	Throbbing Headache	1.6%
691	Labor Pain	1.6%
692	Cancer Pain	1.6%
693	Nociceptive Pain	1.6%
694	Underweight	1.6%
695	Overweight	1.6%
696	Cerebral Amyloid Angiopathy	1.6%
697	Candidemia	1.5%
698	Voice Disorders	1.4%
699	Voice Disturbance	1.4%
700	Gagging	1.4%
701	Akathisia	1.4%
702	Restlessness	1.4%
703	Psychomotor Agitation	1.4%
704	Leukoplakia, Oral	1.4%
705	Vesicovaginal Fistula	1.4%
706	Biliary Fistula	1.3%
707	Gastric Fistula	1.3%
708	Congenital diaphragmatic hernia	1.3%
709	Morning Sickness	1.3%
710	Gait Apraxia	1.3%
711	Anosmia	1.3%
712	Ataxia	1.3%
713	Athetosis	1.3%
714	Catalepsy	1.3%
715	Dental Fistula	1.3%
716	Dystonia	1.3%
717	Hemiplegia	1.3%
718	Locked-In Syndrome	1.3%
719	Muscle Hypertonia	1.3%
720	Muscle hypotonia	1.3%
721	Myoclonus	1.3%
722	Myotonia	1.3%
723	Neuralgia	1.3%
724	Oroantral Fistula	1.3%
725	Paraplegia	1.3%
726	Pseudobulbar Palsy	1.3%
727	Quadriplegia	1.3%
728	Spasm	1.3%
729	Spastic Paraplegia	1.3%
730	Status Epilepticus	1.3%
731	Taste Disorders	1.3%
732	Tremor	1.3%
733	Monoplegia	1.3%
734	Hypokinesia	1.3%
735	Gastroparesis	1.3%
736	Paraparesis	1.3%
737	Bradykinesia	1.3%
738	Waxy flexibility	1.3%
739	Action Tremor	1.3%
740	Resting Tremor	1.3%
741	Dysosmia	1.3%
742	Quadriparesis	1.3%
743	Olfaction Disorders	1.3%
744	Myokymia	1.3%
745	Somatosensory Disorders	1.3%
746	Neuropathic pain	1.3%
747	Hyperkinesia	1.3%
748	Intention tremor	1.3%
749	Rectal Prolapse	1.3%
750	Uterine Prolapse	1.3%
751	Vaginal Prolapse	1.3%
752	Weight Gain	1.3%
753	Jet Lag Syndrome	1.2%
754	Reflex, Abnormal	1.2%
755	Hyporeflexia	1.2%
756	Hyperreflexia	1.2%
757	Emaciation	1.2%
758	Low Back Pain	1.2%
759	Visceral Pain	1.2%
760	Birth Weight	1.2%
761	Vision Disorders	1.1%
762	Metamorphopsia	1.1%
763	Visual Impairment	1.1%
764	Bronchial Fistula	1.1%
765	Metatarsalgia	1.1%
766	Pancreatic Fistula	1.1%
767	Anisocoria	1.1%
768	Confusion	1.1%
769	Facial paralysis	1.1%
770	Intestinal Fistula	1.1%
771	Lethargy	1.1%
772	Memory Disorders	1.1%
773	Muscle Cramp	1.1%
774	Perceptual Disorders	1.1%
775	Psychomotor Disorders	1.1%
776	Tonic Pupil	1.1%
777	Anhedonia	1.1%
778	Disorientation	1.1%
779	Gastroschisis	1.1%
780	Enterocutaneous Fistula	1.1%
781	Fetal Hypoxia	1.1%
782	Facial Paresis	1.1%
783	Memory Loss	1.1%
784	Hemisensory Neglect	1.1%
785	Dysacusis	1.1%
786	Mastodynia	1.1%
787	Respiratory Paralysis	1.1%
788	Salivary Gland Fistula	1.1%
789	Chorea	1.1%
790	Cystocele	1.1%
791	Tetany	1.1%
792	Urinary Incontinence	1.1%
793	Breakthrough Pain	1.1%
794	Albuminuria	1.1%
795	Hemoglobinuria	1.1%
796	Alice in Wonderland Syndrome	1.1%
797	MELAS Syndrome	1.1%
798	Alexia	1%
799	Cachexia	1%
800	Dyslexia	1%
801	Umbilical hernia	1%
802	Hydrops Fetalis	1%
803	Toothache	1%
804	Fetal Weight	1%
805	Hyperemesis Gravidarum	1%
806	Dysgeusia	1%
807	Formication	1%
808	Hyperalgesia	1%
809	Hyperesthesia	1%
810	Hypesthesia	1%
811	Language Disorders	1%
812	Numbness	1%
813	Paresthesia	1%
814	Paraparesis, Spastic	1%
815	Trismus	1%
816	Epilepsia Partialis Continua	1%
817	Hypogeusia	1%
818	Brown-Sequard Syndrome	1%
819	Lockjaw	1%
820	Allodynia	1%
821	Ageusia	1%
822	Brain Hemorrhage, Traumatic	1%
823	Consciousness Disorders	1%
824	Mental Retardation	1%
825	Depressed Level of Consciousness	1%
826	Mental deficiency	1%
827	Intellectual Disability	1%
828	Catatonia	0.9%
829	Musculoskeletal Pain	0.9%
830	Ophthalmoplegia	0.9%
831	External Ophthalmoplegia	0.9%
832	Aphonia	0.9%
833	Arthralgia	0.9%
834	Sleep Deprivation	0.9%
835	Polyarthralgia	0.9%
836	Dysphonia	0.9%
837	Cerebrospinal Fluid Otorrhea	0.9%
838	Cerebrospinal Fluid Rhinorrhea	0.9%
839	Obesity	0.9%
840	Fabry Disease	0.8%
841	Vocal Cord Paralysis	0.8%
842	Diplopia	0.8%
843	Muscle Rigidity	0.8%
844	Muscle Spasticity	0.8%
845	Scotoma	0.8%
846	Photophobia	0.8%
847	Cogwheel Rigidity	0.8%
848	Hemifacial Spasm	0.8%
849	Amaurosis	0.8%
850	Blindness	0.8%
851	Nuchal Rigidity	0.8%
852	Urinary Bladder Fistula	0.8%
853	Agnosia	0.8%
854	Apraxias	0.8%
855	Hallucinations	0.8%
856	Hemianopsia	0.8%
857	Hyperacusis	0.8%
858	Tinnitus	0.8%
859	Visual Agnosia	0.8%
860	Anosognosia	0.8%
861	Wernicke-Korsakoff Syndrome	0.8%
862	Phonophobia	0.8%
863	Hearing Loss	0.8%
864	Cerebellar Ataxia	0.8%
865	Torticollis	0.8%
866	Tinea Pedis	0.8%
867	Sciatica	0.8%
868	Urge Incontinence	0.8%
869	Tardive Dyskinesia	0.8%
870	Agraphia	0.8%
871	Anomia	0.8%
872	Cluttering	0.8%
873	Language Development Disorders	0.8%
874	Speech Disorders	0.8%
875	Syncope	0.8%
876	Stupor	0.8%
877	Dysgraphia	0.8%
878	Presyncope	0.8%
879	Dyslalia	0.8%
880	Dyskinesia, Drug-Induced	0.7%
881	Alcohol Withdrawal Seizures	0.7%
882	Aphasia	0.7%
883	Articulation Disorders	0.7%
884	Echolalia	0.7%
885	Stuttering	0.7%
886	Dysphasia	0.7%
887	Amblyopia	0.7%
888	Amnesia	0.7%
889	Delirium	0.7%
890	Horner Syndrome	0.7%
891	Dissociative Amnesia	0.7%
892	Color blindness	0.7%
893	Global Amnesia	0.7%
894	Rectal Fistula	0.7%
895	Anal Fistula	0.7%
896	Shoulder Pain	0.7%
897	Pediatric Obesity	0.7%
898	Dysarthria	0.7%
899	Amaurosis Fugax	0.7%
900	Blindness, Cortical	0.7%
901	Dyscalculia	0.7%
902	Deafness	0.7%
903	Hearing Loss, Sudden	0.7%
904	Gerstmann Syndrome	0.7%
905	Hearing Loss, Bilateral	0.7%
906	Hearing Loss, High-Frequency	0.7%
907	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
908	Prosopagnosia	0.7%
909	Apraxia, Ideomotor	0.7%
910	Persistent Vegetative State	0.7%
911	Charles Bonnet Syndrome	0.7%
912	Hearing Loss, Unilateral	0.7%
913	Complete Hearing Loss	0.7%
914	Alien Hand Syndrome	0.7%
915	Deaf Mutism	0.7%
916	Kidney Calculi	0.6%
917	Ureteral Calculi	0.6%
918	Akathisia, Drug-Induced	0.6%
919	Myalgia	0.6%
920	Mutism	0.6%
921	Selective Mutism	0.6%
922	Retrograde amnesia	0.6%
923	Amnesia, Anterograde	0.6%
924	Alexia, Pure	0.6%
925	Auditory Perceptual Disorders	0.5%
926	Amnesia, Transient Global	0.5%
927	Ophthalmoplegic Migraine	0.5%
928	Progressive supranuclear palsy	0.5%

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