MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lateral Medullary Syndrome

(UMLS:C0043019)

Definition:: INFARCTION of the dorsolateral aspect of MEDULLA OBLONGATA in the BRAIN STEM. It is caused by occlusion of the VERTEBRAL ARTERY and/or the posterior inferior cerebellar artery. Clinical manifestations vary with the size of infarction, but may include loss of pain and temperature sensation in the ipsilateral face and contralateral body below the chin; ipsilateral HORNER SYNDROME; ipsilateral ATAXIA; DYSARTHRIA; VERTIGO; nausea, hiccup; dysphagia; and VOCAL CORD PARALYSIS. (From Adams et al., Principles of Neurology, 6th ed, p801)
UMLS ID:: C0043019
MeSH ID:: D014854

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.150.477.100.500|C10.228.140.300.775.200.100.500

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.092.477.100.500|C14.907.253.855.200.100.500

Synonym(s)

Lateral Medullary Syndrome

Inferior cerebellar artery syndrome

LATERAL BULBAR SYNDROME

LMS - Lateral medullary syndrome

Lateral medullary syndrome

Posterior inferior cerebellar artery syndrome

VIEUSSEUX-WALLENBERG SYNDROME

WALLENBERG SYNDROME

Wallenberg Syndrome

10.

Wallenberg syndrome

11.

Wallenberg's Syndrome

12.

Wallenberg's syndrome

13.

lateral medullary syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Minocycline	FAERS: 3		US FAERS
2	Rivaroxaban	FAERS: 3		US FAERS
3	Thyroxine	FAERS: 2		US FAERS
4	teriflunomide	FAERS: 2		US FAERS
5	Celecoxib	FAERS: 1		US FAERS
6	Droxidopa	FAERS: 1		US FAERS
7	Methamphetamine	FAERS: 1		US FAERS
8	Minocycline	FAERS: 1		US FAERS
9	carbidopa, levodopa drug combination	FAERS: 1		US FAERS
10	iopromide	FAERS: 1		US FAERS
11	rofecoxib	FAERS: 1		US FAERS
12	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride			OFFSIDES
13	Aspirin		10929277	CTD
14	Buprenorphine			OFFSIDES
15	Cocaine		3399066	CTD
16	Glyburide			OFFSIDES
17	Levetiracetam			OFFSIDES
18	Phenprocoumon			OFFSIDES
19	tizanidine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cerebral Infarction	45.5%
2	Basal Ganglia Cerebrovascular Disease	36.9%
3	Carotid Artery Diseases	34.7%
4	Vasospasm, Intracranial	34.7%
5	Intracranial Arterial Diseases	34.7%
6	Vascular Headaches	33.7%
7	Intracranial Embolism and Thrombosis	33.2%
8	Hypoxia-Ischemia, Brain	32.6%
9	Leukomalacia, Periventricular	32.5%
10	Vasculitis, Central Nervous System	31.5%
11	Infarction, Middle Cerebral Artery	31.1%
12	Infarction, Anterior Cerebral Artery	31.1%
13	Infarction, Posterior Cerebral Artery	31.1%
14	Vertebrobasilar Insufficiency	29.6%
15	Basilar Artery Stenosis	29.6%
16	Vertebral Artery Stenosis	29.6%
17	Transient Cerebral Ischemia	29.6%
18	Dementia, Vascular	26.5%
19	Moyamoya Disease	25.3%
20	Carotid Artery Injuries	24.6%
21	Carotid Artery Thrombosis	23.1%
22	Carotid Stenosis	22.6%
23	Intracranial Aneurysm	22.6%
24	Basal Ganglia Hemorrhage	21.1%
25	Spinal Cord Vascular Diseases	20.6%
26	Encephalomyelitis	20.2%
27	Intracranial Arteriosclerosis	19.8%
28	Cerebral Atherosclerosis	19.8%
29	Cerebral Arteriosclerosis	19.8%
30	Subdural Effusion	19.4%
31	Meningoencephalitis	19.3%
32	Cerebral Arterial Diseases	19.1%
33	Intracranial Hemorrhage, Hypertensive	19.1%
34	Akinetic Mutism	18.9%
35	Anoxic Encephalopathy	18.9%
36	Basal Ganglia Diseases	18.9%
37	Brain Damage, Chronic	18.9%
38	Cerebellar Diseases	18.9%
39	Encephalitis	18.9%
40	Encephalomalacia	18.9%
41	Epilepsy	18.9%
42	Hydrocephalus	18.9%
43	Congenital Hydrocephalus	18.9%
44	Hypothalamic Diseases	18.9%
45	Thalamic Diseases	18.9%
46	Intracranial Hypertension	18.9%
47	Aura	18.9%
48	Leukoencephalopathy	18.9%
49	Neuroaxonal Dystrophies	18.9%
50	Headache Disorders	18.9%
51	Intracranial Hypotension	18.9%
52	Brain Edema	18.9%
53	Brain Hypoxia	18.9%
54	Aqueductal Stenosis	18.9%
55	Myocardial Ischemia	18.6%
56	Cerebral Thrombosis	18.4%
57	Intracranial Embolism	18.4%
58	Intracranial Thrombosis	18.4%
59	Subarachnoid Hemorrhage, Traumatic	18.2%
60	Pituitary Apoplexy	18.1%
61	Subclavian Steal Syndrome	17.7%
62	Brain Ischemia	17.3%
63	Cerebrovascular accident	17.3%
64	Brain Abscess	17.3%
65	Pneumocephalus	17.2%
66	Vertebral Artery Dissection	17.1%
67	Multiple System Atrophy	16.6%
68	Aneurysm	16.4%
69	Angiomatosis	16.4%
70	Aortic Diseases	16.4%
71	Arterial Occlusive Diseases	16.4%
72	Hyperemia	16.4%
73	Hypotension	16.4%
74	Superior Vena Cava Syndrome	16.4%
75	Telangiectasis	16.4%
76	Vasculitis	16.4%
77	Venous Insufficiency	16.4%
78	Peripheral Vascular Diseases	16.4%
79	Embolism and Thrombosis	16.4%
80	Angiodysplasia	16.4%
81	Capillary Leak Syndrome	16.4%
82	Prehypertension	16.4%
83	Subarachnoid Hemorrhage	16.4%
84	Cerebral Hemorrhage	16.4%
85	Giant Cell Arteritis	16.2%
86	Temporal Arteritis	16.2%
87	Dandy-Walker Syndrome	16.1%
88	Brain Diseases, Metabolic	16.1%
89	Dementia	16.1%
90	Meningitis	15.9%
91	Movement Disorders	15.9%
92	Pachymeningitis	15.9%
93	Spinal Cord Diseases	15.9%
94	Ocular Motility Disorders	15.9%
95	Cyclophoria	15.9%
96	Lupus Vasculitis, Central Nervous System	15.9%
97	Brain Injuries	15.7%
98	Brain Neoplasms	15.6%
99	Carotid Artery, Internal, Dissection	15.4%
100	Parkinsonian Disorders	15.1%
101	Thoracic Outlet Syndrome	14.9%
102	Aortic Aneurysm	14.4%
103	Aortitis	14.4%
104	Leriche Syndrome	14.4%
105	Periphlebitis	14.4%
106	Phlebitis	14.4%
107	Thromboangiitis Obliterans	14.4%
108	Brain Infarction	14.4%
109	Vascular System Injuries	14.2%
110	Hand-Arm Vibration Syndrome	14.2%
111	Lewy Body Disease	14.2%
112	Retinal Vein Occlusion	14%
113	Optic Neuropathy, Ischemic	14%
114	Anterior Ischemic Optic Neuropathy	14%
115	Brain Death	13.9%
116	Compartment syndromes	13.9%
117	Hepatic Veno-Occlusive Disease	13.9%
118	Peliosis Hepatis	13.9%
119	Varicocele	13.9%
120	Central Nervous System Infection	13.8%
121	Diabetic Angiopathies	13.8%
122	Reperfusion Injury	13.8%
123	Splenic Infarction	13.8%
124	Vascular Neoplasms	13.8%
125	Vasoplegia	13.8%
126	Hemorrhoids	13.7%
127	Myelitis	13.6%
128	Epilepsy, Post-Traumatic	13.4%
129	Putaminal Hemorrhage	13.1%
130	Epidural Abscess	12.9%
131	Myocardial Reperfusion Injury	12.9%
132	Amblyopia	12.9%
133	Posterior Leukoencephalopathy Syndrome	12.9%
134	Posterior reversible encephalopathy syndrome	12.9%
135	Marchiafava-Bignami Disease	12.9%
136	Shy-Drager Syndrome	12.6%
137	Malignant Atrophic Papulosis	12.4%
138	Shwartzman Phenomenon	12.4%
139	Brain Hemorrhage, Traumatic	12.2%
140	Stiff-Person Syndrome	12%
141	Mesenteric vascular insufficiency	12%
142	Meige Syndrome	11.9%
143	Cerebral Ventriculitis	11.9%
144	Angioedema	11.7%
145	Colitis, Ischemic	11.7%
146	Huntington Disease	11.6%
147	Prion Diseases	11.3%
148	MELAS Syndrome	11.3%
149	Postphlebitic Syndrome	11.2%
150	Sinus Thrombosis, Intracranial	11.1%
151	Neuroleptic Malignant Syndrome	11.1%
152	Myelinolysis, Central Pontine	11.1%
153	Amnesia, Transient Global	11%
154	Heart Diseases	10.9%
155	Parkinson Disease	10.9%
156	Progressive supranuclear palsy	10.9%
157	Spinal Cord Ischemia	10.8%
158	Cranial nerve diseases	10.7%
159	Demyelinating Diseases	10.7%
160	Demyelination	10.7%
161	Neuromuscular Diseases	10.7%
162	Chronobiology Disorders	10.7%
163	Dystonia Musculorum Deformans	10.7%
164	Coronary Aneurysm	10.7%
165	Subacute Combined Degeneration	10.6%
166	Arteriovenous fistula	10.3%
167	Creutzfeldt-Jakob disease	10.3%
168	Cerebellar Neoplasms	10.2%
169	Sturge-Weber Syndrome	10.1%
170	Spinal Cord Injuries	10%
171	Cerebral Palsy	10%
172	Epilepsies, Partial	10%
173	Epilepsy, Generalized	10%
174	Pseudotumor Cerebri	10%
175	Hypertensive Encephalopathy	10%
176	Simple Partial Seizures	10%
177	Epilepsy, Reflex	10%
178	Headache Disorders, Primary	10%
179	Headache Disorders, Secondary	10%
180	Medication overuse headache	10%
181	Scimitar Syndrome	9.9%
182	Cerebral Amyloid Angiopathy	9.8%
183	Spinal Muscular Atrophy	9.8%
184	Progressive Muscular Atrophy	9.8%
185	Asterixis	9.8%
186	Ballismus	9.8%
187	Coronary heart disease	9.6%
188	Myocardial Infarction	9.6%
189	Acute Coronary Syndrome	9.6%
190	Limbic Encephalitis	9.5%
191	Trauma, Nervous System	9.3%
192	Leukoencephalopathy, Progressive Multifocal	9.3%
193	Pregnancy Complications, Cardiovascular	9.2%
194	Cardiovascular Abnormalities	9.2%
195	Myoclonic Epilepsy	9.2%
196	Epilepsy, Temporal Lobe	9.2%
197	Epilepsy, Rolandic	9.2%
198	Benign Rolandic Epilepsy	9.2%
199	Amyotrophic Lateral Sclerosis	9.2%
200	Presenile dementia	9.2%
201	Senile dementia	9.2%
202	Nervous System Neoplasms	9.1%
203	Neurologic Manifestations	9.1%
204	Neurotoxicity Syndromes	9.1%
205	Aortic Rupture	9.1%
206	Motor Neuron Disease	9%
207	Hepatolenticular Degeneration	9%
208	Meningitis, Bacterial	8.9%
209	Meningitis, Fungal	8.9%
210	Chronic Fatigue Syndrome	8.9%
211	Thrombophlebitis	8.8%
212	Striatonigral Degeneration	8.8%
213	Poliomyelitis	8.8%
214	Blue Toe Syndrome	8.7%
215	Pituitary Diseases	8.6%
216	Aneurysm, Dissecting	8.6%
217	Arteriosclerosis	8.6%
218	Arteritis	8.6%
219	Embolism	8.6%
220	Erythromelalgia	8.6%
221	Fibromuscular Dysplasia	8.6%
222	Malignant Hypertension	8.6%
223	Raynaud Disease	8.6%
224	Thromboembolism	8.6%
225	Thrombosis	8.6%
226	Essential Hypertension	8.6%
227	Aneurysm, Ruptured	8.6%
228	Iliac Aneurysm	8.6%
229	Pulmonary artery stenosis	8.6%
230	White Coat Hypertension	8.6%
231	Systemic Vasculitis	8.6%
232	Embolus	8.6%
233	Brain Stem Infarctions	8.6%
234	Hypotension, Orthostatic	8.4%
235	Kluver-Bucy Syndrome	8.4%
236	Post-Exercise Hypotension	8.4%
237	Kounis Syndrome	8.4%
238	Restless Legs Syndrome	8.3%
239	Ataxia Telangiectasia	8.3%
240	May-Thurner Syndrome	8.2%
241	Angina Pectoris	8.2%
242	Brain Injuries, Diffuse	8.2%
243	Traumatic Brain Injury	8.2%
244	Cerebellar Ataxia	8.2%
245	Supratentorial Neoplasms	8.2%
246	Arachnoiditis	8.1%
247	Aseptic Meningitis	8.1%
248	Syringomyelia	8.1%
249	Essential Tremor	8.1%
250	Familial Tremor	8.1%
251	Pneumorrhachis	8.1%
252	Writer's Cramp	8.1%
253	Paraneoplastic Cerebellar Degeneration	8%
254	Coronary Thrombosis	7.9%
255	Coronary Artery Disease	7.9%
256	Aortic Aneurysm, Abdominal	7.9%
257	Aortic Aneurysm, Thoracic	7.9%
258	Sleep Wake Disorders	7.9%
259	Fabry Disease	7.9%
260	Spinal Cord Neoplasms	7.8%
261	Ophthalmoplegic Migraine	7.8%
262	Polyradiculoneuropathy	7.7%
263	Polyradiculoneuritis	7.7%
264	Persistent Vegetative State	7.7%
265	Toxoplasmosis, Cerebral	7.6%
266	Akathisia, Drug-Induced	7.6%
267	Hematoma, Subdural	7.6%
268	Hematoma, Epidural, Cranial	7.6%
269	Cavernous Sinus Thrombosis	7.5%
270	Sagittal Sinus Thrombosis	7.5%
271	Embolism, Amniotic Fluid	7.4%
272	Miller Fisher Syndrome	7.4%
273	Retinal Artery Occlusion	7.3%
274	Retinal Vasculitis	7.3%
275	Hypertensive Retinopathy	7.3%
276	Reye Syndrome	7.2%
277	Anterior Compartment Syndrome	7.2%
278	Vasculitis, Leukocytoclastic, Cutaneous	7.2%
279	Gastric Antral Vascular Ectasia	7.2%
280	Abdominal Compartment Syndrome	7.2%
281	Leukoencephalitis, Acute Hemorrhagic	7.2%
282	Hepatic Encephalopathy	7.2%
283	Varicose Ulcer	7.2%
284	Primary Graft Dysfunction	7.2%
285	Myelitis, Transverse	7.1%
286	Opsoclonus-Myoclonus Syndrome	7%
287	MPTP Poisoning	6.9%
288	Encephalomyelitis, Acute Disseminated	6.9%
289	Central Nervous System Fungal Infections	6.9%
290	Conus Medullaris Syndrome	6.9%
291	Polyarteritis Nodosa	6.8%
292	Takayasu Arteritis	6.8%
293	Autonomic Dysreflexia	6.7%
294	Complex Regional Pain Syndromes	6.7%
295	CREST Syndrome	6.7%
296	Mitochondrial Encephalomyopathies	6.4%
297	Brain Diseases, Metabolic, Inborn	6.3%
298	Pituitary Adenoma	6.3%
299	Pituitary Neoplasms	6.3%
300	Dyskinesia, Drug-Induced	6.3%
301	Friedreich Ataxia	6.3%
302	Mesenteric Vascular Occlusion	6.3%
303	Mucocutaneous Lymph Node Syndrome	6.3%
304	Diabetic Retinopathy	6.2%
305	Livedo Reticularis	6.2%
306	Renal hypertension	6.2%
307	Renal Artery Obstruction	6.2%
308	Renal Artery Stenosis	6.2%
309	Hemangioma, Cavernous	6.2%
310	Scurvy	6.1%
311	Canavan Disease	6%
312	Alexander Disease	6%
313	Central Nervous System Bacterial Infections	6%
314	Anterior Spinal Artery Syndrome	5.9%
315	Peripheral Nerve Injuries	5.9%
316	Myasthenia Gravis	5.8%
317	Auditory Perceptual Disorders	5.8%
318	Lateral Medullary Syndrome	5.7%
319	Wernicke Encephalopathy	5.6%
320	AIDS Dementia Complex	5.6%
321	Post-Traumatic Headache	5.5%
322	Tension Headache	5.5%
323	Epilepsy, Complex Partial	5.5%
324	Migraine Disorders	5.5%
325	Abdominal Migraine	5.5%
326	Status Migrainosus	5.5%
327	Cervicogenic Headache	5.5%
328	Juvenile Myoclonic Epilepsy	5.5%
329	Myoclonic Epilepsies, Progressive	5.5%
330	Cardiac Tamponade	5.5%
331	Endocarditis	5.5%
332	Cardiac Arrest	5.5%
333	Heart failure	5.5%
334	Pericardial effusion	5.5%
335	Pericarditis	5.5%
336	Pneumopericardium	5.5%
337	Cor pulmonale	5.5%
338	Ventricular Outflow Obstruction	5.5%
339	Ventricular Dysfunction	5.5%
340	Cardiomyopathies	5.5%
341	Pleuropericarditis	5.5%
342	Lambert-Eaton Myasthenic Syndrome	5.5%
343	Ischemic contracture	5.5%
344	Angioedemas, Hereditary	5.4%
345	Tricuspid Atresia	5.4%
346	Arrhythmogenic Right Ventricular Dysplasia	5.4%
347	Cryoglobulinemia	5.4%
348	Diabetic Foot	5.4%
349	Bacterial Endocarditis	5.3%
350	Dysautonomia	5.3%
351	Vagus Nerve Disorder	5.3%
352	Glossopharyngeal Neuralgia	5.3%
353	Abducens Nerve Diseases	5.3%
354	Heavy Metal Poisoning, Nervous System	5.3%
355	Neuromuscular Junction Diseases	5.3%
356	Tauopathies	5.3%
357	Trochlear Nerve Diseases	5.3%
358	Peripheral Nervous System Diseases	5.3%
359	Coronary Occlusion	5.3%
360	Microvascular Angina	5.3%
361	Coronary Stenosis	5.3%
362	ST segment elevation myocardial infarction	5.3%
363	Sleep Disorders, Circadian Rhythm	5.2%
364	Dural Arteriovenous Fistula	5.2%
365	Kernicterus	5.1%
366	Scrapie	5.1%
367	Central Cord Syndrome	5.1%
368	Botulism	5.1%
369	Central Nervous System Cysts	5.1%
370	Chorea	5%
371	Tuberculosis, Meningeal	5%
372	Guillain-Barre Syndrome	5%
373	Hematoma, Subdural, Intracranial	5%
374	Hematoma, Subdural, Chronic	5%
375	Hematoma, Subdural, Acute	5%
376	Aortic Valve Stenosis	4.8%
377	Cardiomyopathy, Dilated	4.8%
378	Pulmonary Valve Stenosis	4.8%
379	Purpura, Hyperglobulinemic	4.8%
380	Arteriosclerosis Obliterans	4.7%
381	Atherosclerosis	4.7%
382	Air Embolism	4.7%
383	Endarteritis	4.7%
384	Venous Thrombosis	4.7%
385	Deep Vein Thrombosis	4.7%
386	Venous Thromboembolism	4.7%
387	Empty Sella Syndrome	4.7%
388	Hyperpituitarism	4.7%
389	Hypopituitarism	4.7%
390	Hypophysitis	4.7%
391	Cardiac Output, High	4.6%
392	Myocardial Stunning	4.6%
393	Low Cardiac Output Syndrome	4.6%
394	Myopathy	4.6%
395	Optic Neuropathy	4.6%
396	Cardiomegaly	4.6%
397	Postpericardiotomy Syndrome	4.6%
398	Cardiac Hypertrophy	4.6%
399	Shock, Cardiogenic	4.6%
400	Rheumatic Heart Disease	4.6%
401	Progressive bulbar palsy	4.5%
402	Bulbar palsy	4.5%
403	Angina, Unstable	4.5%
404	Adrenoleukodystrophy	4.5%
405	Diffuse Axonal Injury	4.5%
406	Brain Stem Neoplasms	4.5%
407	Facial Nerve Diseases	4.5%
408	Craniocerebral Trauma	4.5%
409	Parasomnia	4.5%
410	Dyssomnias	4.5%
411	Lafora Disease	4.5%
412	Unverricht-Lundborg Syndrome	4.5%
413	Vestibulocochlear Nerve Diseases	4.5%
414	Decerebrate State	4.5%
415	Hemiparesis	4.5%
416	Hydranencephaly	4.5%
417	Meningism	4.5%
418	Neural Tube Defects	4.5%
419	Paresis	4.5%
420	Seizures	4.5%
421	Sensation Disorders	4.5%
422	Tethered Cord Syndrome	4.5%
423	Central Nervous System Neoplasms	4.5%
424	Complex partial seizures	4.5%
425	Iniencephaly	4.5%
426	Craniorachischisis	4.5%
427	Exencephaly	4.5%
428	Monoparesis	4.5%
429	Septo-Optic Dysplasia	4.5%
430	Cortical Dysplasia	4.5%
431	Neurogenic Inflammation	4.5%
432	Gait Disorders, Neurologic	4.5%
433	Neuromuscular Manifestations	4.5%
434	Malformations of Cortical Development	4.5%
435	Sweating, Gustatory	4.4%
436	Auriculotemporal Syndrome	4.4%
437	Behcet Syndrome	4.4%
438	Waldenstrom Macroglobulinemia	4.4%
439	Multiple Myeloma	4.4%
440	Frontotemporal dementia	4.4%
441	Olfactory Nerve Injuries	4.3%
442	Horner Syndrome	4.2%
443	Meningitis, Cryptococcal	4.2%
444	Meningitis, Listeria	4.2%
445	Meningitis, Haemophilus	4.2%
446	Meningitis, Pneumococcal	4.2%
447	Heart Block	4.1%
448	Tachycardia	4.1%
449	Tachyarrhythmia	4.1%
450	Aortic coarctation	4.1%
451	Cor Triatriatum	4.1%
452	Coronary Vessel Anomalies	4.1%
453	Patent ductus arteriosus	4.1%
454	Ebstein Anomaly	4.1%
455	Heart Septal Defects	4.1%
456	Tetralogy of Fallot	4.1%
457	Transposition of Great Vessels	4.1%
458	Hypoplastic Left Heart Syndrome	4.1%
459	Neuromyelitis Optica	4.1%
460	Torticollis	4.1%
461	Intermittent Claudication	4%
462	Pulmonary Embolism	4%
463	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	4%
464	Pseudoxanthoma Elasticum	4%
465	Causalgia	4%
466	No-Reflow Phenomenon	4%
467	Brain Contusion	4%
468	Pupil Disorders	3.9%
469	Neurobehavioral Manifestations	3.9%
470	Brain Concussion	3.9%
471	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	3.9%
472	Multiple Sclerosis	3.9%
473	Lemierre Syndrome	3.9%
474	Paraneoplastic Encephalomyelitis	3.9%
475	Facial Nerve Injuries	3.8%
476	Uveomeningoencephalitic Syndrome	3.8%
477	Vertigo	3.8%
478	Alcohol-Induced Disorders, Nervous System	3.8%
479	Jet Lag Syndrome	3.8%
480	Tuberous Sclerosis	3.8%
481	Subacute Sclerosing Panencephalitis	3.8%
482	Dextrocardia	3.6%
483	Long QT Syndrome	3.6%
484	Tuberculosis, Central Nervous System	3.6%
485	Refsum Disease	3.5%
486	Myasthenia Gravis, Autoimmune, Experimental	3.5%
487	Reflex Sympathetic Dystrophy	3.5%
488	Nocturnal Myoclonus Syndrome	3.5%
489	Ophthalmoplegia	3.5%
490	External Ophthalmoplegia	3.5%
491	Voice Disorders	3.4%
492	Voice Disturbance	3.4%
493	Hypertension, Renovascular	3.4%
494	Carcinoid Heart Disease	3.4%
495	Hereditary Angioedema Type III	3.4%
496	Hereditary Angioedema Types I and II	3.4%
497	Smith-Magenis syndrome	3.4%
498	Cluster Headache	3.3%
499	Migraine with Aura	3.3%
500	Familial Hemiplegic Migraine	3.3%
501	Chronic Paroxysmal Hemicrania	3.3%
502	SUNCT Syndrome	3.3%
503	Paroxysmal Hemicrania	3.3%
504	Hypertrophic Cardiomyopathy	3.2%
505	Hypertrophic obstructive cardiomyopathy	3.2%
506	Coronary Restenosis	3.2%
507	Alice in Wonderland Syndrome	3.1%
508	Vocal Cord Paralysis	3.1%
509	Neuroaspergillosis	3.1%
510	Reflex, Abnormal	3%
511	Hyporeflexia	3%
512	Hyperreflexia	3%
513	Acrodynia	3%
514	Noonan Syndrome	2.9%
515	Aortic Valve Insufficiency	2.9%
516	Restrictive cardiomyopathy	2.9%
517	Endocardial Fibroelastosis	2.9%
518	Heart Rupture, Post-Infarction	2.9%
519	Mitral Valve Insufficiency	2.9%
520	Mitral Valve Stenosis	2.9%
521	Myocarditis	2.9%
522	Pericarditis, Constrictive	2.9%
523	Pulmonary Valve Insufficiency	2.9%
524	Tricuspid Valve Insufficiency	2.9%
525	Tricuspid Valve Stenosis	2.9%
526	Ventricular Dysfunction, Left	2.9%
527	Right Ventricular Dysfunction	2.9%
528	Endomyocardial Fibrosis	2.9%
529	Carditis	2.9%
530	Heart Failure, Systolic	2.9%
531	Heart Failure, Diastolic	2.9%
532	Pseudorabies	2.8%
533	Galactosemias	2.8%
534	Urea Cycle Disorders, Inborn	2.8%
535	Tyrosinemias	2.8%
536	Hyperprolactinemia	2.8%
537	Pick Disease of the Brain	2.8%
538	Charcot-Marie-Tooth Disease	2.8%
539	Alcohol Withdrawal Seizures	2.7%
540	Tardive Dyskinesia	2.7%
541	Neuritis	2.7%
542	Polyneuritis	2.7%
543	Radiculitis	2.7%
544	Polyneuropathy	2.7%
545	Mononeuritis	2.7%
546	Mononeuropathies	2.7%
547	Brachial Plexus Neuropathies	2.7%
548	Radiculopathy	2.7%
549	Mononeuropathy Multiplex	2.7%
550	Nerve Root Compression	2.7%
551	Angina Pectoris, Variant	2.7%
552	Choroid Plexus Papilloma	2.7%
553	Marfan Syndrome	2.7%
554	Neurosyphilis	2.7%
555	Rheumatoid Vasculitis	2.7%
556	Sick Sinus Syndrome	2.7%
557	Supravalvular aortic stenosis	2.6%
558	Lown-Ganong-Levine Syndrome	2.6%
559	Myotonia Congenita	2.6%
560	Cerebrospinal Fluid Otorrhea	2.6%
561	Cerebrospinal Fluid Rhinorrhea	2.6%
562	Neuritis, Autoimmune, Experimental	2.6%
563	Gait Ataxia	2.6%
564	Homocystinuria	2.6%
565	Leigh Disease	2.5%
566	Subacute Bacterial Endocarditis	2.5%
567	Hepatic Vein Thrombosis	2.4%
568	Budd-Chiari Syndrome	2.4%
569	Sinus Arrhythmia	2.4%
570	Atrial Fibrillation	2.4%
571	Atrial Flutter	2.4%
572	Edema, Cardiac	2.4%
573	Ventricular Fibrillation	2.4%
574	Ventricular Flutter	2.4%
575	Parasystole	2.4%
576	Paroxysmal atrial fibrillation	2.4%
577	Bradycardia	2.4%
578	Diabetic Cardiomyopathies	2.4%
579	Acromegaly	2.4%
580	Cardiomyopathy, Alcoholic	2.4%
581	Ectopia Cordis	2.4%
582	Sudden Cardiac Death	2.4%
583	Left Ventricular Hypertrophy	2.4%
584	Right Ventricular Hypertrophy	2.4%
585	Single umbilical artery	2.4%
586	Lyme Neuroborreliosis	2.4%
587	Chagas Cardiomyopathy	2.4%
588	Pulmonary Infarction	2.4%
589	Brachial Plexus Neuritis	2.4%
590	Neuralgic Amyotrophy	2.4%
591	Akathisia	2.3%
592	Restlessness	2.3%
593	Psychomotor Agitation	2.3%
594	Myositis	2.3%
595	Optic Atrophy	2.3%
596	Optic Neuritis	2.3%
597	Papilledema	2.3%
598	Strabismus	2.3%
599	Tolosa-Hunt Syndrome	2.3%
600	Isaacs syndrome	2.3%
601	Arsenic Poisoning	2.3%
602	Myotonic Disorders	2.3%
603	Myasthenic Syndromes, Congenital	2.3%
604	Menkes Kinky Hair Syndrome	2.3%
605	Coma, Post-Head Injury	2.3%
606	Myotonic Dystrophy	2.3%
607	Adams-Stokes Syndrome	2.3%
608	Atrioventricular Block	2.3%
609	Bundle-Branch Block	2.3%
610	Atrial Premature Complexes	2.3%
611	Sinoatrial Block	2.3%
612	Tachycardia, Paroxysmal	2.3%
613	Supraventricular tachycardia	2.3%
614	Tachycardia, Ventricular	2.3%
615	Wolff-Parkinson-White Syndrome	2.3%
616	Tachycardia, Reciprocating	2.3%
617	Diabetic Neuropathies	2.3%
618	Facial Injuries	2.3%
619	Facial Neuralgia	2.3%
620	Diabetic Amyotrophy	2.3%
621	Diabetic Autonomic Neuropathy	2.3%
622	Sleep Talking	2.3%
623	Manganese Poisoning	2.3%
624	Sleep Disorders, Intrinsic	2.3%
625	Orthostatic intolerance	2.3%
626	Aortopulmonary Septal Defect	2.3%
627	Double Outlet Right Ventricle	2.3%
628	Endocardial Cushion Defects	2.3%
629	Myocardial bridging	2.3%
630	Aorticopulmonary Septal Defect	2.3%
631	Anosmia	2.3%
632	Ataxia	2.3%
633	Athetosis	2.3%
634	Catalepsy	2.3%
635	Dystonia	2.3%
636	Hemiplegia	2.3%
637	Locked-In Syndrome	2.3%
638	Meningeal Neoplasms	2.3%
639	Meningomyelocele	2.3%
640	Muscle Hypertonia	2.3%
641	Muscle hypotonia	2.3%
642	Myoclonus	2.3%
643	Myotonia	2.3%
644	Neuralgia	2.3%
645	Paraplegia	2.3%
646	Pseudobulbar Palsy	2.3%
647	Quadriplegia	2.3%
648	Spasm	2.3%
649	Spastic Paraplegia	2.3%
650	Status Epilepticus	2.3%
651	Taste Disorders	2.3%
652	Tremor	2.3%
653	Spina Bifida	2.3%
654	Monoplegia	2.3%
655	Hypokinesia	2.3%
656	Paraparesis	2.3%
657	Bradykinesia	2.3%
658	Waxy flexibility	2.3%
659	Action Tremor	2.3%
660	Resting Tremor	2.3%
661	Dysosmia	2.3%
662	Quadriparesis	2.3%
663	Mercury Poisoning, Nervous System	2.3%
664	Olfaction Disorders	2.3%
665	Myokymia	2.3%
666	Lead Poisoning, Nervous System	2.3%
667	Vestibular Neuronitis	2.3%
668	Somatosensory Disorders	2.3%
669	Neuropathic pain	2.3%
670	Hyperkinesia	2.3%
671	Intention tremor	2.3%
672	West Nile Fever	2.1%
673	Acoustic Neuroma	2.1%
674	Dyspnea, Paroxysmal	2.1%
675	Granulomatosis with polyangiitis	2.1%
676	Multiple Sclerosis, Chronic Progressive	2%
677	Multiple Sclerosis, Relapsing-Remitting	2%
678	Zellweger Syndrome	2%
679	Vision Disorders	2%
680	Metamorphopsia	2%
681	Visual Impairment	2%
682	Fibromyalgia	2%
683	Medial Tibial Stress Syndrome	2%
684	Romano-Ward Syndrome	2%
685	Facial Hemiatrophy	2%
686	Melkersson-Rosenthal Syndrome	2%
687	Mitochondrial Myopathies	2%
688	Anisocoria	2%
689	Confusion	2%
690	Facial paralysis	2%
691	Lethargy	2%
692	Memory Disorders	2%
693	Muscle Cramp	2%
694	Perceptual Disorders	2%
695	Psychomotor Disorders	2%
696	Tonic Pupil	2%
697	Eosinophilia-Myalgia Syndrome	2%
698	Anhedonia	2%
699	Disorientation	2%
700	Facial Paresis	2%
701	Memory Loss	2%
702	Hemisensory Neglect	2%
703	Dysacusis	2%
704	Sleep Bruxism	2%
705	Anencephaly	1.9%
706	Meningocele	1.9%
707	Muscular Atrophy	1.9%
708	Respiratory Paralysis	1.9%
709	Encephalocele	1.9%
710	Gait Apraxia	1.9%
711	Tetany	1.9%
712	Alstrom Syndrome	1.9%
713	Amyloid Neuropathies, Familial	1.9%
714	Kearns-Sayre syndrome	1.9%
715	Prolactinoma	1.9%
716	Growth Hormone-Secreting Pituitary Adenoma	1.9%
717	Tarsal Tunnel Syndrome	1.8%
718	Cauda Equina Syndrome	1.8%
719	Optic Nerve Glioma	1.8%
720	Duane Retraction Syndrome	1.7%
721	Consciousness Disorders	1.7%
722	Mental Retardation	1.7%
723	Muscle Weakness	1.7%
724	Depressed Level of Consciousness	1.7%
725	Mental deficiency	1.7%
726	Intellectual Disability	1.7%
727	Mobius Syndrome	1.7%
728	Bell Palsy	1.7%
729	Catatonia	1.7%
730	Herpes Zoster Oticus	1.7%
731	Toxoplasmosis, Congenital	1.7%
732	Familial Periodic Paralysis	1.7%
733	Malaria, Cerebral	1.7%
734	Aphonia	1.7%
735	Sleep Deprivation	1.7%
736	Dysphonia	1.7%
737	Neurocysticercosis	1.7%
738	Turner Syndrome	1.7%
739	Carpal Tunnel Syndrome	1.6%
740	neurofibroma	1.6%
741	Sciatica	1.6%
742	Aortic Valve Prolapse	1.6%
743	Tricuspid Valve Prolapse	1.6%
744	Takotsubo Cardiomyopathy	1.6%
745	Myalgia	1.5%
746	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.5%
747	Neuronal Ceroid-Lipofuscinoses	1.5%
748	Williams Syndrome	1.5%
749	Waterhouse-Friderichsen Syndrome	1.5%
750	Sciatic Neuropathy	1.4%
751	Ulnar Neuropathies	1.4%
752	Lesion of Sciatic Nerve	1.4%
753	Ulnar Neuritis	1.4%
754	Radial nerve compression	1.4%
755	Radial Tunnel Syndrome	1.4%
756	Peroneal Neuropathies	1.4%
757	Radial Neuropathy	1.4%
758	Median Neuropathy	1.4%
759	Sciatic Nerve Palsy	1.4%
760	Femoral Neuropathy	1.4%
761	Tibial Neuropathy	1.4%
762	Ulnar Nerve Palsy	1.4%
763	Postural Orthostatic Tachycardia Syndrome	1.4%
764	Radial nerve palsy	1.4%
765	Aicardi's syndrome	1.4%
766	Hoarseness	1.4%
767	Nelson Syndrome	1.4%
768	Glycogen storage disease type II	1.4%
769	Cockayne Syndrome	1.4%
770	Alcohol Withdrawal Delirium	1.4%
771	Tachycardia, Atrioventricular Nodal Reentry	1.4%
772	Tachycardia, Ectopic Atrial	1.4%
773	Tachycardia, Ectopic Junctional	1.4%
774	Sinus Tachycardia	1.4%
775	Torsades de Pointes	1.4%
776	Accelerated Idioventricular Rhythm	1.4%
777	Truncus Arteriosus, Persistent	1.4%
778	Sinus Arrest, Cardiac	1.3%
779	Holoprosencephaly	1.3%
780	Classical Lissencephalies and Subcortical Band Heterotopias	1.2%
781	Esotropia	1.2%
782	Exotropia	1.2%
783	Sleep Apnea Syndromes	1.2%
784	Polymyositis	1.2%
785	Disorders of Excessive Somnolence	1.2%
786	Sleep Initiation and Maintenance Disorders	1.2%
787	Night Terrors	1.2%
788	Somnambulism	1.2%
789	Trigeminal Nerve Disorder	1.2%
790	Transient Insomnia	1.2%
791	Sleep Paralysis	1.2%
792	Chronic Insomnia	1.2%
793	REM Sleep Behavior Disorder	1.2%
794	Hypersomnia	1.2%
795	Dermal Sinus	1.2%
796	Dysgeusia	1.2%
797	Formication	1.2%
798	Hyperalgesia	1.2%
799	Hyperesthesia	1.2%
800	Hypesthesia	1.2%
801	Language Disorders	1.2%
802	Numbness	1.2%
803	Paresthesia	1.2%
804	Paraparesis, Spastic	1.2%
805	Spina Bifida Cystica	1.2%
806	Trismus	1.2%
807	Spina Bifida Occulta	1.2%
808	Epilepsia Partialis Continua	1.2%
809	Hypogeusia	1.2%
810	Meningeal Carcinomatosis	1.2%
811	Brown-Sequard Syndrome	1.2%
812	Lissencephaly	1.2%
813	Polymicrogyria	1.2%
814	Pachygyria	1.2%
815	Schizencephaly	1.2%
816	Lockjaw	1.2%
817	Allodynia	1.2%
818	Lead Poisoning, Nervous System, Childhood	1.2%
819	Lead Poisoning, Nervous System, Adult	1.2%
820	Periventricular Nodular Heterotopia	1.2%
821	Ageusia	1.2%
822	Cubital Tunnel Syndrome	1.1%
823	Eye Injuries	1.1%
824	Muscular Dystrophy	1%
825	Congenital nystagmus	1%
826	Orbital Myositis	1%
827	Diplopia	1%
828	Muscle Rigidity	1%
829	Muscle Spasticity	1%
830	Scotoma	1%
831	Photophobia	1%
832	Cogwheel Rigidity	1%
833	Hemifacial Spasm	1%
834	Amaurosis	1%
835	Blindness	1%
836	Nuchal Rigidity	1%
837	Pyomyositis	1%
838	Kartagener Syndrome	1%
839	Agnosia	1%
840	Apraxias	1%
841	Hallucinations	1%
842	Hemianopsia	1%
843	Hyperacusis	1%
844	Tinnitus	1%
845	Visual Agnosia	1%
846	Anosognosia	1%
847	Wernicke-Korsakoff Syndrome	1%
848	Phonophobia	1%
849	Hearing Loss	1%
850	Optic Atrophy, Hereditary, Leber	1%
851	Sarcopenia	1%
852	Amnesia	0.9%
853	Delirium	0.9%
854	Dissociative Amnesia	0.9%
855	Color blindness	0.9%
856	Global Amnesia	0.9%
857	Cri-du-Chat Syndrome	0.9%
858	Down Syndrome	0.9%
859	Trisomy 21	0.9%
860	POEMS Syndrome	0.9%
861	Meningioma	0.9%
862	Microcephaly	0.9%
863	Macrocephaly	0.9%
864	Hypokalemic periodic paralysis	0.9%
865	Porencephaly	0.9%
866	Alexia	0.9%
867	Dyslexia	0.9%
868	Gaucher Disease	0.8%
869	Prader-Willi Syndrome	0.8%
870	Phantom pain	0.8%
871	Phantom Limb Pain	0.8%
872	Polyradiculopathy	0.8%
873	Neurofibrosarcoma	0.7%
874	Rubinstein-Taybi Syndrome	0.7%
875	Sleep Apnea, Obstructive	0.7%
876	Sleep Apnea, Central	0.7%
877	Narcolepsy	0.7%
878	Trigeminal Neuralgia	0.7%
879	Kleine-Levin Syndrome	0.7%
880	Agraphia	0.7%
881	Anomia	0.7%
882	Cluttering	0.7%
883	Language Development Disorders	0.7%
884	Speech Disorders	0.7%
885	Syncope	0.7%
886	Stupor	0.7%
887	Dysgraphia	0.7%
888	Presyncope	0.7%
889	Dyslalia	0.7%
890	Niemann-Pick Disease, Type C	0.6%
891	Eye Burns	0.6%
892	Welander Distal Myopathy	0.6%
893	Amaurosis Fugax	0.6%
894	Blindness, Cortical	0.6%
895	Dyscalculia	0.6%
896	Rett Syndrome	0.6%
897	Deafness	0.6%
898	Hearing Loss, Sudden	0.6%
899	Gerstmann Syndrome	0.6%
900	Hearing Loss, Bilateral	0.6%
901	Hearing Loss, High-Frequency	0.6%
902	Hearing Loss, Mixed Conductive-Sensorineural	0.6%
903	Prosopagnosia	0.6%
904	Apraxia, Ideomotor	0.6%
905	Charles Bonnet Syndrome	0.6%
906	Hearing Loss, Unilateral	0.6%
907	Complete Hearing Loss	0.6%
908	Alien Hand Syndrome	0.6%
909	Deaf Mutism	0.6%
910	Tay-Sachs Disease	0.5%
911	Dermatomyositis	0.5%
912	Corneal Scar	0.5%
913	Muscular Dystrophy, Duchenne	0.5%
914	Retrograde amnesia	0.5%
915	Amnesia, Anterograde	0.5%
916	Fragile X Syndrome	0.4%
917	Cataplexy	0.4%
918	Aphasia	0.4%
919	Articulation Disorders	0.4%
920	Echolalia	0.4%
921	Stuttering	0.4%
922	Dysphasia	0.4%
923	Mutism	0.3%
924	Selective Mutism	0.3%
925	Mucopolysaccharidosis II	0.3%
926	Corneal Perforation	0.3%
927	Dysarthria	0.3%
928	Alexia, Pure	0.2%

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