MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sinus Thrombosis, Intracranial

(UMLS:C0037198)

Definition:: Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects.
UMLS ID:: C0037198
MeSH ID:: D012851

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.525.425.500

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.566.350.500|C14.907.355.590.213.350.500

Synonym(s)

Sinus Thrombosis, Intracranial

Sinus thrombosis

brain; thrombosis, sinus

intracranial sinus thrombosis

sinus thrombosis

sinus; thrombosis

thrombosis; brain, sinus

thrombosis; sinus

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Aspirin	12269725	CTD
2	Danazol	9248340	CTD
3	Desogestrel	9593414	CTD
4	Estradiol	8638876	CTD
5	Folic Acid	18786290	CTD
6	Gestodene	9593414	CTD
7	Idarubicin	18832917	CTD
8	Medroxyprogesterone Acetate	887403	CTD
9	Mercaptopurine	4056835	CTD
10	Nandrolone Decanoate	15579201	CTD
11	Norethindrone Acetate	18786290	CTD
12	Norinyl	20500972	CTD
13	Progesterone	8638876	CTD
14	Tamoxifen	11320192 14745086	CTD
15	Thalidomide	15256794	CTD
16	Tranexamic Acid	3590072	CTD
17	Tretinoin	18832917	CTD
18	Vitamin B 12	18786290	CTD
19	Vitamin B 6	18786290	CTD
20	Warfarin	12269725 18786290	CTD
21	etonogestrel	20500972	CTD
22	norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination	98825	CTD
23	reviparin	View details 12269725 12763334 16038130 17660937	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Intracranial Embolism	40.1%
2	Carotid Artery Thrombosis	35.5%
3	Basal Ganglia Cerebrovascular Disease	27.7%
4	Carotid Artery Diseases	27.6%
5	Brain Ischemia	27.6%
6	Cerebrovascular accident	27.6%
7	Vasospasm, Intracranial	27.6%
8	Intracranial Arterial Diseases	27.6%
9	Vascular Headaches	25.7%
10	Vasculitis, Central Nervous System	25.2%
11	Leukomalacia, Periventricular	23.8%
12	Brain Infarction	23.2%
13	Myocardial Ischemia	23.2%
14	Moyamoya Disease	22.5%
15	Spinal Cord Vascular Diseases	21.6%
16	Aneurysm	21.3%
17	Angiomatosis	21.3%
18	Aortic Diseases	21.3%
19	Arterial Occlusive Diseases	21.3%
20	Hyperemia	21.3%
21	Hypotension	21.3%
22	Superior Vena Cava Syndrome	21.3%
23	Telangiectasis	21.3%
24	Vasculitis	21.3%
25	Venous Insufficiency	21.3%
26	Peripheral Vascular Diseases	21.3%
27	Angiodysplasia	21.3%
28	Capillary Leak Syndrome	21.3%
29	Prehypertension	21.3%
30	Carotid Stenosis	21.2%
31	Intracranial Aneurysm	21.2%
32	Carotid Artery Injuries	19%
33	Retinal Vein Occlusion	18.9%
34	Dementia, Vascular	18.6%
35	Embolism	18.6%
36	Thrombosis	18.6%
37	Embolus	18.6%
38	Venous Thromboembolism	18.5%
39	Aortic Aneurysm	18.4%
40	Aortitis	18.4%
41	Leriche Syndrome	18.4%
42	Periphlebitis	18.4%
43	Phlebitis	18.4%
44	Thromboangiitis Obliterans	18.4%
45	Hypoxia-Ischemia, Brain	18.2%
46	Intracranial Arteriosclerosis	17.9%
47	Cerebral Atherosclerosis	17.9%
48	Cerebral Arteriosclerosis	17.9%
49	Thoracic Outlet Syndrome	17.9%
50	Vascular System Injuries	17.9%
51	Compartment syndromes	17.4%
52	Hepatic Veno-Occlusive Disease	17.4%
53	Peliosis Hepatis	17.4%
54	Varicocele	17.4%
55	Diabetic Angiopathies	17.2%
56	Reperfusion Injury	17.2%
57	Splenic Infarction	17.2%
58	Vascular Neoplasms	17.2%
59	Vasoplegia	17.2%
60	Hemorrhoids	17%
61	Basal Ganglia Hemorrhage	16.7%
62	Cerebral Arterial Diseases	16.2%
63	Vertebrobasilar Insufficiency	16.2%
64	Basilar Artery Stenosis	16.2%
65	Vertebral Artery Stenosis	16.2%
66	Intracranial Hemorrhage, Hypertensive	16.2%
67	Transient Cerebral Ischemia	16.2%
68	Hand-Arm Vibration Syndrome	16.1%
69	Optic Neuropathy, Ischemic	15.7%
70	Anterior Ischemic Optic Neuropathy	15.7%
71	Subarachnoid Hemorrhage, Traumatic	15.6%
72	Myocardial Reperfusion Injury	15.4%
73	Malignant Atrophic Papulosis	15.4%
74	Shwartzman Phenomenon	15.3%
75	Cerebral Infarction	15.1%
76	Brain Stem Infarctions	15.1%
77	Infarction, Middle Cerebral Artery	14.5%
78	Infarction, Anterior Cerebral Artery	14.5%
79	Infarction, Posterior Cerebral Artery	14.5%
80	Mesenteric vascular insufficiency	14.5%
81	Vertebral Artery Dissection	14.5%
82	Postphlebitic Syndrome	14.4%
83	Giant Cell Arteritis	14.3%
84	Temporal Arteritis	14.3%
85	Angioedema	14.2%
86	Pituitary Apoplexy	14.2%
87	Colitis, Ischemic	14.2%
88	Heart Diseases	14.1%
89	Carotid Artery, Internal, Dissection	13.7%
90	Subarachnoid Hemorrhage	13.5%
91	Cerebral Hemorrhage	13.5%
92	Coronary Aneurysm	13.5%
93	Thrombophlebitis	13.1%
94	Coronary Thrombosis	12.9%
95	Blue Toe Syndrome	12.8%
96	Encephalomyelitis	12.7%
97	Akinetic Mutism	12.6%
98	Anoxic Encephalopathy	12.6%
99	Basal Ganglia Diseases	12.6%
100	Brain Damage, Chronic	12.6%
101	Cerebellar Diseases	12.6%
102	Encephalitis	12.6%
103	Encephalomalacia	12.6%
104	Epilepsy	12.6%
105	Hydrocephalus	12.6%
106	Congenital Hydrocephalus	12.6%
107	Hypothalamic Diseases	12.6%
108	Thalamic Diseases	12.6%
109	Intracranial Hypertension	12.6%
110	Aura	12.6%
111	Leukoencephalopathy	12.6%
112	Neuroaxonal Dystrophies	12.6%
113	Headache Disorders	12.6%
114	Intracranial Hypotension	12.6%
115	Brain Edema	12.6%
116	Brain Hypoxia	12.6%
117	Aqueductal Stenosis	12.6%
118	Subdural Effusion	12.5%
119	Coronary heart disease	12.3%
120	Myocardial Infarction	12.3%
121	Acute Coronary Syndrome	12.3%
122	Arteriovenous fistula	12.2%
123	Meningoencephalitis	12%
124	Embolism, Amniotic Fluid	12%
125	Lupus Vasculitis, Central Nervous System	11.7%
126	Spinal Cord Ischemia	11.5%
127	Scimitar Syndrome	11.5%
128	Aortic Rupture	11.5%
129	Putaminal Hemorrhage	11.4%
130	Aneurysm, Dissecting	11.4%
131	Arteriosclerosis	11.4%
132	Arteritis	11.4%
133	Erythromelalgia	11.4%
134	Fibromuscular Dysplasia	11.4%
135	Malignant Hypertension	11.4%
136	Raynaud Disease	11.4%
137	Essential Hypertension	11.4%
138	Aneurysm, Ruptured	11.4%
139	Iliac Aneurysm	11.4%
140	Pulmonary artery stenosis	11.4%
141	White Coat Hypertension	11.4%
142	Systemic Vasculitis	11.4%
143	Pregnancy Complications, Cardiovascular	11.4%
144	Cardiovascular Abnormalities	11.4%
145	Lateral Medullary Syndrome	11.1%
146	Embolism and Thrombosis	11%
147	Shy-Drager Syndrome	10.8%
148	Subclavian Steal Syndrome	10.6%
149	Pneumocephalus	10.5%
150	Air Embolism	10.5%
151	Venous Thrombosis	10.5%
152	Deep Vein Thrombosis	10.5%
153	Brain Abscess	10.5%
154	Aortic Aneurysm, Abdominal	10.5%
155	Aortic Aneurysm, Thoracic	10.5%
156	Kounis Syndrome	10.4%
157	Meningitis	10.4%
158	Movement Disorders	10.4%
159	Pachymeningitis	10.4%
160	Spinal Cord Diseases	10.4%
161	Brain Diseases, Metabolic	10.3%
162	Dementia	10.3%
163	Multiple System Atrophy	10.3%
164	Coronary Artery Disease	10.2%
165	May-Thurner Syndrome	10.2%
166	Angina Pectoris	10.2%
167	Dandy-Walker Syndrome	10.1%
168	Sturge-Weber Syndrome	10.1%
169	Hypotension, Orthostatic	9.9%
170	Parkinsonian Disorders	9.9%
171	Post-Exercise Hypotension	9.9%
172	Brain Injuries	9.7%
173	Ocular Motility Disorders	9.7%
174	Cyclophoria	9.7%
175	Brain Neoplasms	9.7%
176	Retinal Artery Occlusion	9.3%
177	Retinal Vasculitis	9.3%
178	Hypertensive Retinopathy	9.3%
179	Anterior Compartment Syndrome	9.2%
180	Vasculitis, Leukocytoclastic, Cutaneous	9.2%
181	Gastric Antral Vascular Ectasia	9.2%
182	Abdominal Compartment Syndrome	9.2%
183	Varicose Ulcer	9.1%
184	Primary Graft Dysfunction	9.1%
185	Brain Hemorrhage, Traumatic	8.9%
186	Lewy Body Disease	8.9%
187	Posterior Leukoencephalopathy Syndrome	8.9%
188	Posterior reversible encephalopathy syndrome	8.9%
189	Cerebral Amyloid Angiopathy	8.9%
190	Polyarteritis Nodosa	8.8%
191	Takayasu Arteritis	8.8%
192	Myelitis	8.7%
193	Brain Death	8.7%
194	Central Nervous System Infection	8.7%
195	Pulmonary Embolism	8.6%
196	Epilepsy, Post-Traumatic	8.6%
197	Marchiafava-Bignami Disease	8.4%
198	MELAS Syndrome	8.4%
199	Cerebrovascular Disorders	8.3%
200	Cerebrovascular Insufficiency	8.3%
201	CREST Syndrome	8%
202	Meige Syndrome	8%
203	Cerebral Ventriculitis	8%
204	Epidural Abscess	7.9%
205	Amblyopia	7.9%
206	Mesenteric Vascular Occlusion	7.8%
207	Mucocutaneous Lymph Node Syndrome	7.8%
208	Diabetic Retinopathy	7.7%
209	Livedo Reticularis	7.7%
210	Renal hypertension	7.7%
211	Renal Artery Obstruction	7.7%
212	Renal Artery Stenosis	7.7%
213	Hemangioma, Cavernous	7.6%
214	Scurvy	7.6%
215	Ataxia Telangiectasia	7.4%
216	Stiff-Person Syndrome	7.2%
217	Prion Diseases	7.2%
218	Parkinson Disease	7.1%
219	Huntington Disease	7.1%
220	Cardiac Tamponade	7.1%
221	Endocarditis	7.1%
222	Cardiac Arrest	7.1%
223	Heart failure	7.1%
224	Pericardial effusion	7.1%
225	Pericarditis	7.1%
226	Pneumopericardium	7.1%
227	Cor pulmonale	7.1%
228	Ventricular Outflow Obstruction	7.1%
229	Ventricular Dysfunction	7.1%
230	Cardiomyopathies	7.1%
231	Pleuropericarditis	7.1%
232	Neuroleptic Malignant Syndrome	7.1%
233	Myelinolysis, Central Pontine	7.1%
234	Coronary Occlusion	7%
235	Microvascular Angina	7%
236	Coronary Stenosis	7%
237	ST segment elevation myocardial infarction	7%
238	Cerebral Palsy	6.9%
239	Epilepsies, Partial	6.9%
240	Epilepsy, Generalized	6.9%
241	Pseudotumor Cerebri	6.9%
242	Hypertensive Encephalopathy	6.9%
243	Simple Partial Seizures	6.9%
244	Epilepsy, Reflex	6.9%
245	Headache Disorders, Primary	6.9%
246	Headache Disorders, Secondary	6.9%
247	Medication overuse headache	6.9%
248	Cranial nerve diseases	6.9%
249	Demyelinating Diseases	6.9%
250	Demyelination	6.9%
251	Neuromuscular Diseases	6.9%
252	Chronobiology Disorders	6.9%
253	Dystonia Musculorum Deformans	6.8%
254	Creutzfeldt-Jakob disease	6.7%
255	Cerebellar Neoplasms	6.7%
256	Anterior Spinal Artery Syndrome	6.7%
257	Myoclonic Epilepsy	6.6%
258	Epilepsy, Temporal Lobe	6.6%
259	Epilepsy, Rolandic	6.6%
260	Benign Rolandic Epilepsy	6.6%
261	Ischemic contracture	6.6%
262	Amnesia, Transient Global	6.6%
263	Angioedemas, Hereditary	6.6%
264	Tricuspid Atresia	6.6%
265	Arrhythmogenic Right Ventricular Dysplasia	6.6%
266	Cryoglobulinemia	6.6%
267	Arteriosclerosis Obliterans	6.5%
268	Atherosclerosis	6.5%
269	Endarteritis	6.5%
270	Progressive supranuclear palsy	6.5%
271	Diabetic Foot	6.5%
272	Bacterial Endocarditis	6.4%
273	Hematoma, Subdural	6.4%
274	Hematoma, Epidural, Cranial	6.4%
275	Subacute Combined Degeneration	6.3%
276	Spinal Cord Injuries	6.2%
277	Aortic Valve Stenosis	6.1%
278	Cardiomyopathy, Dilated	6.1%
279	Pulmonary Valve Stenosis	6.1%
280	Spinal Muscular Atrophy	6.1%
281	Progressive Muscular Atrophy	6.1%
282	Intracranial Embolism and Thrombosis	6%
283	Asterixis	6%
284	Ballismus	6%
285	Thromboembolism	6%
286	Limbic Encephalitis	5.9%
287	Fabry Disease	5.9%
288	Presenile dementia	5.9%
289	Senile dementia	5.9%
290	Shock, Cardiogenic	5.9%
291	Lemierre Syndrome	5.9%
292	Pituitary Diseases	5.8%
293	Angina, Unstable	5.8%
294	Cardiac Output, High	5.8%
295	Myocardial Stunning	5.8%
296	Low Cardiac Output Syndrome	5.8%
297	Trauma, Nervous System	5.8%
298	Leukoencephalopathy, Progressive Multifocal	5.8%
299	Purpura, Hyperglobulinemic	5.7%
300	Striatonigral Degeneration	5.7%
301	Cardiomegaly	5.7%
302	Postpericardiotomy Syndrome	5.7%
303	Cardiac Hypertrophy	5.7%
304	Rheumatic Heart Disease	5.7%
305	Meningitis, Bacterial	5.6%
306	Meningitis, Fungal	5.6%
307	Motor Neuron Disease	5.6%
308	Nervous System Neoplasms	5.6%
309	Neurologic Manifestations	5.6%
310	Neurotoxicity Syndromes	5.6%
311	Kluver-Bucy Syndrome	5.6%
312	Amyotrophic Lateral Sclerosis	5.5%
313	Poliomyelitis	5.4%
314	Arachnoiditis	5.4%
315	Aseptic Meningitis	5.4%
316	Syringomyelia	5.4%
317	Essential Tremor	5.4%
318	Familial Tremor	5.4%
319	Pneumorrhachis	5.4%
320	Writer's Cramp	5.4%
321	Chronic Fatigue Syndrome	5.4%
322	Intermittent Claudication	5.4%
323	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5.4%
324	Hepatolenticular Degeneration	5.3%
325	Hepatic Vein Thrombosis	5.3%
326	Budd-Chiari Syndrome	5.3%
327	Brain Injuries, Diffuse	5.3%
328	Traumatic Brain Injury	5.3%
329	Cerebellar Ataxia	5.3%
330	Supratentorial Neoplasms	5.3%
331	No-Reflow Phenomenon	5.3%
332	Pulmonary Infarction	5.3%
333	Behcet Syndrome	5.2%
334	Waldenstrom Macroglobulinemia	5.1%
335	Multiple Myeloma	5.1%
336	Heart Block	5.1%
337	Tachycardia	5.1%
338	Tachyarrhythmia	5.1%
339	Aortic coarctation	5.1%
340	Cor Triatriatum	5.1%
341	Coronary Vessel Anomalies	5.1%
342	Patent ductus arteriosus	5.1%
343	Ebstein Anomaly	5.1%
344	Heart Septal Defects	5.1%
345	Tetralogy of Fallot	5.1%
346	Transposition of Great Vessels	5.1%
347	Hypoplastic Left Heart Syndrome	5.1%
348	Paraneoplastic Cerebellar Degeneration	5.1%
349	Persistent Vegetative State	5%
350	Restless Legs Syndrome	4.9%
351	Spinal Cord Neoplasms	4.8%
352	Sleep Wake Disorders	4.8%
353	Toxoplasmosis, Cerebral	4.7%
354	Ophthalmoplegic Migraine	4.7%
355	Reye Syndrome	4.7%
356	Pseudoxanthoma Elasticum	4.7%
357	Hepatic Encephalopathy	4.7%
358	MPTP Poisoning	4.6%
359	Hematoma, Subdural, Intracranial	4.6%
360	Hematoma, Subdural, Chronic	4.6%
361	Hematoma, Subdural, Acute	4.6%
362	Polyradiculoneuropathy	4.6%
363	Polyradiculoneuritis	4.6%
364	Leukoencephalitis, Acute Hemorrhagic	4.6%
365	Akathisia, Drug-Induced	4.5%
366	Encephalomyelitis, Acute Disseminated	4.5%
367	Miller Fisher Syndrome	4.5%
368	Coronary Restenosis	4.4%
369	Juvenile Myoclonic Epilepsy	4.4%
370	Myoclonic Epilepsies, Progressive	4.4%
371	Central Nervous System Fungal Infections	4.4%
372	Conus Medullaris Syndrome	4.4%
373	Dextrocardia	4.4%
374	Long QT Syndrome	4.4%
375	Hypertension, Renovascular	4.4%
376	Hereditary Angioedema Type III	4.4%
377	Hereditary Angioedema Types I and II	4.4%
378	Pituitary Adenoma	4.3%
379	Pituitary Neoplasms	4.3%
380	Autonomic Dysreflexia	4.2%
381	Complex Regional Pain Syndromes	4.2%
382	Dural Arteriovenous Fistula	4.2%
383	Myelitis, Transverse	4.2%
384	Hypertrophic Cardiomyopathy	4.2%
385	Hypertrophic obstructive cardiomyopathy	4.2%
386	Post-Traumatic Headache	4.2%
387	Tension Headache	4.2%
388	Epilepsy, Complex Partial	4.2%
389	Migraine Disorders	4.2%
390	Abdominal Migraine	4.2%
391	Status Migrainosus	4.2%
392	Cervicogenic Headache	4.2%
393	Friedreich Ataxia	4.1%
394	Opsoclonus-Myoclonus Syndrome	4.1%
395	Brain Diseases, Metabolic, Inborn	4.1%
396	Mitochondrial Encephalomyopathies	4%
397	Carcinoid Heart Disease	4%
398	Canavan Disease	3.9%
399	Alexander Disease	3.9%
400	Aortic Valve Insufficiency	3.8%
401	Restrictive cardiomyopathy	3.8%
402	Endocardial Fibroelastosis	3.8%
403	Heart Rupture, Post-Infarction	3.8%
404	Mitral Valve Insufficiency	3.8%
405	Mitral Valve Stenosis	3.8%
406	Myocarditis	3.8%
407	Pericarditis, Constrictive	3.8%
408	Pulmonary Valve Insufficiency	3.8%
409	Tricuspid Valve Insufficiency	3.8%
410	Tricuspid Valve Stenosis	3.8%
411	Ventricular Dysfunction, Left	3.8%
412	Right Ventricular Dysfunction	3.8%
413	Endomyocardial Fibrosis	3.8%
414	Carditis	3.8%
415	Heart Failure, Systolic	3.8%
416	Heart Failure, Diastolic	3.8%
417	Dyskinesia, Drug-Induced	3.8%
418	Central Nervous System Bacterial Infections	3.7%
419	Angina Pectoris, Variant	3.7%
420	Peripheral Nerve Injuries	3.6%
421	Auditory Perceptual Disorders	3.6%
422	Cerebral Thrombosis	3.6%
423	Intracranial Thrombosis	3.6%
424	Myasthenia Gravis	3.6%
425	Wernicke Encephalopathy	3.5%
426	AIDS Dementia Complex	3.5%
427	Supravalvular aortic stenosis	3.5%
428	Lown-Ganong-Levine Syndrome	3.5%
429	Dysautonomia	3.5%
430	Vagus Nerve Disorder	3.5%
431	Glossopharyngeal Neuralgia	3.5%
432	Abducens Nerve Diseases	3.5%
433	Heavy Metal Poisoning, Nervous System	3.5%
434	Neuromuscular Junction Diseases	3.5%
435	Tauopathies	3.5%
436	Trochlear Nerve Diseases	3.5%
437	Peripheral Nervous System Diseases	3.5%
438	Noonan Syndrome	3.5%
439	Lafora Disease	3.4%
440	Unverricht-Lundborg Syndrome	3.4%
441	Empty Sella Syndrome	3.4%
442	Hyperpituitarism	3.4%
443	Hypopituitarism	3.4%
444	Hypophysitis	3.4%
445	Rheumatoid Vasculitis	3.3%
446	Sick Sinus Syndrome	3.3%
447	Tuberculosis, Meningeal	3.3%
448	Scrapie	3.3%
449	Central Cord Syndrome	3.3%
450	Chorea	3.2%
451	Kernicterus	3.2%
452	Lambert-Eaton Myasthenic Syndrome	3.2%
453	Diffuse Axonal Injury	3.2%
454	Brain Stem Neoplasms	3.2%
455	Marfan Syndrome	3.1%
456	Sleep Disorders, Circadian Rhythm	3.1%
457	Sinus Arrhythmia	3.1%
458	Atrial Fibrillation	3.1%
459	Atrial Flutter	3.1%
460	Edema, Cardiac	3.1%
461	Ventricular Fibrillation	3.1%
462	Ventricular Flutter	3.1%
463	Parasystole	3.1%
464	Paroxysmal atrial fibrillation	3.1%
465	Bradycardia	3.1%
466	Diabetic Cardiomyopathies	3.1%
467	Cardiomyopathy, Alcoholic	3%
468	Ectopia Cordis	3%
469	Sudden Cardiac Death	3%
470	Left Ventricular Hypertrophy	3%
471	Right Ventricular Hypertrophy	3%
472	Single umbilical artery	3%
473	Botulism	3%
474	Central Nervous System Cysts	3%
475	Chagas Cardiomyopathy	3%
476	Guillain-Barre Syndrome	3%
477	Subacute Bacterial Endocarditis	3%
478	Frontotemporal dementia	3%
479	Adams-Stokes Syndrome	2.9%
480	Atrioventricular Block	2.9%
481	Bundle-Branch Block	2.9%
482	Atrial Premature Complexes	2.9%
483	Sinoatrial Block	2.9%
484	Tachycardia, Paroxysmal	2.9%
485	Supraventricular tachycardia	2.9%
486	Tachycardia, Ventricular	2.9%
487	Wolff-Parkinson-White Syndrome	2.9%
488	Tachycardia, Reciprocating	2.9%
489	Aortopulmonary Septal Defect	2.9%
490	Double Outlet Right Ventricle	2.9%
491	Endocardial Cushion Defects	2.9%
492	Myocardial bridging	2.9%
493	Aorticopulmonary Septal Defect	2.9%
494	Progressive bulbar palsy	2.9%
495	Bulbar palsy	2.9%
496	Myopathy	2.9%
497	Optic Neuropathy	2.9%
498	Adrenoleukodystrophy	2.9%
499	Granulomatosis with polyangiitis	2.8%
500	Facial Nerve Diseases	2.8%
501	Craniocerebral Trauma	2.8%
502	Parasomnia	2.8%
503	Dyssomnias	2.8%
504	Vestibulocochlear Nerve Diseases	2.8%
505	Decerebrate State	2.8%
506	Hemiparesis	2.8%
507	Hydranencephaly	2.8%
508	Meningism	2.8%
509	Neural Tube Defects	2.8%
510	Paresis	2.8%
511	Seizures	2.8%
512	Sensation Disorders	2.8%
513	Tethered Cord Syndrome	2.8%
514	Central Nervous System Neoplasms	2.8%
515	Complex partial seizures	2.8%
516	Iniencephaly	2.8%
517	Craniorachischisis	2.8%
518	Exencephaly	2.8%
519	Monoparesis	2.8%
520	Septo-Optic Dysplasia	2.8%
521	Cortical Dysplasia	2.8%
522	Neurogenic Inflammation	2.8%
523	Gait Disorders, Neurologic	2.8%
524	Neuromuscular Manifestations	2.8%
525	Malformations of Cortical Development	2.8%
526	Cluster Headache	2.8%
527	Migraine with Aura	2.8%
528	Familial Hemiplegic Migraine	2.8%
529	Chronic Paroxysmal Hemicrania	2.8%
530	SUNCT Syndrome	2.8%
531	Paroxysmal Hemicrania	2.8%
532	Sweating, Gustatory	2.8%
533	Auriculotemporal Syndrome	2.8%
534	Meningitis, Cryptococcal	2.7%
535	Meningitis, Listeria	2.7%
536	Brain Contusion	2.7%
537	Meningitis, Haemophilus	2.7%
538	Meningitis, Pneumococcal	2.7%
539	Torticollis	2.7%
540	Olfactory Nerve Injuries	2.6%
541	Subacute Sclerosing Panencephalitis	2.6%
542	Brain Concussion	2.6%
543	Dyspnea, Paroxysmal	2.6%
544	Horner Syndrome	2.6%
545	Causalgia	2.5%
546	Romano-Ward Syndrome	2.5%
547	Neuromyelitis Optica	2.4%
548	Multiple Sclerosis	2.4%
549	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.4%
550	Pupil Disorders	2.4%
551	Neurobehavioral Manifestations	2.4%
552	Tuberculosis, Central Nervous System	2.4%
553	Sinus Thrombosis, Intracranial	2.4%
554	Paraneoplastic Encephalomyelitis	2.3%
555	Facial Nerve Injuries	2.3%
556	Uveomeningoencephalitic Syndrome	2.3%
557	Vertigo	2.3%
558	Alcohol-Induced Disorders, Nervous System	2.3%
559	Jet Lag Syndrome	2.2%
560	Reflex Sympathetic Dystrophy	2.2%
561	Nocturnal Myoclonus Syndrome	2.2%
562	Hyperprolactinemia	2.2%
563	Pick Disease of the Brain	2.2%
564	Aortic Valve Prolapse	2.2%
565	Tricuspid Valve Prolapse	2.2%
566	Takotsubo Cardiomyopathy	2.2%
567	Refsum Disease	2.2%
568	Tuberous Sclerosis	2.2%
569	Alice in Wonderland Syndrome	2.1%
570	Ophthalmoplegia	2.1%
571	External Ophthalmoplegia	2.1%
572	Choroid Plexus Papilloma	2.1%
573	Myasthenia Gravis, Autoimmune, Experimental	2.1%
574	Voice Disorders	2%
575	Voice Disturbance	2%
576	Neuroaspergillosis	2%
577	Smith-Magenis syndrome	2%
578	Turner Syndrome	1.9%
579	Acromegaly	1.9%
580	Acrodynia	1.9%
581	Galactosemias	1.9%
582	Urea Cycle Disorders, Inborn	1.9%
583	Tyrosinemias	1.9%
584	Vocal Cord Paralysis	1.9%
585	Tardive Dyskinesia	1.9%
586	Tachycardia, Atrioventricular Nodal Reentry	1.8%
587	Tachycardia, Ectopic Atrial	1.8%
588	Tachycardia, Ectopic Junctional	1.8%
589	Sinus Tachycardia	1.8%
590	Torsades de Pointes	1.8%
591	Accelerated Idioventricular Rhythm	1.8%
592	Truncus Arteriosus, Persistent	1.8%
593	Pseudorabies	1.8%
594	Neuritis	1.8%
595	Polyneuritis	1.8%
596	Radiculitis	1.8%
597	Polyneuropathy	1.8%
598	Mononeuritis	1.8%
599	Mononeuropathies	1.8%
600	Brachial Plexus Neuropathies	1.8%
601	Radiculopathy	1.8%
602	Mononeuropathy Multiplex	1.8%
603	Nerve Root Compression	1.8%
604	Cavernous Sinus Thrombosis	1.8%
605	Sagittal Sinus Thrombosis	1.8%
606	Sinus Arrest, Cardiac	1.8%
607	Reflex, Abnormal	1.7%
608	Hyporeflexia	1.7%
609	Hyperreflexia	1.7%
610	Kearns-Sayre syndrome	1.7%
611	Neurosyphilis	1.7%
612	Charcot-Marie-Tooth Disease	1.7%
613	Homocystinuria	1.7%
614	Leigh Disease	1.7%
615	West Nile Fever	1.6%
616	Myotonia Congenita	1.6%
617	Alcohol Withdrawal Seizures	1.6%
618	Cerebrospinal Fluid Otorrhea	1.6%
619	Cerebrospinal Fluid Rhinorrhea	1.6%
620	Neuritis, Autoimmune, Experimental	1.6%
621	Gait Ataxia	1.6%
622	Brachial Plexus Neuritis	1.6%
623	Neuralgic Amyotrophy	1.6%
624	Lyme Neuroborreliosis	1.5%
625	Menkes Kinky Hair Syndrome	1.5%
626	Coma, Post-Head Injury	1.5%
627	Myositis	1.5%
628	Optic Atrophy	1.5%
629	Optic Neuritis	1.5%
630	Papilledema	1.5%
631	Strabismus	1.5%
632	Tolosa-Hunt Syndrome	1.5%
633	Isaacs syndrome	1.5%
634	Arsenic Poisoning	1.5%
635	Myotonic Disorders	1.5%
636	Myasthenic Syndromes, Congenital	1.5%
637	Diabetic Neuropathies	1.5%
638	Facial Injuries	1.5%
639	Facial Neuralgia	1.5%
640	Diabetic Amyotrophy	1.5%
641	Diabetic Autonomic Neuropathy	1.5%
642	Sleep Talking	1.5%
643	Manganese Poisoning	1.5%
644	Sleep Disorders, Intrinsic	1.5%
645	Orthostatic intolerance	1.5%
646	Anosmia	1.4%
647	Ataxia	1.4%
648	Athetosis	1.4%
649	Catalepsy	1.4%
650	Dystonia	1.4%
651	Hemiplegia	1.4%
652	Locked-In Syndrome	1.4%
653	Meningeal Neoplasms	1.4%
654	Meningomyelocele	1.4%
655	Muscle Hypertonia	1.4%
656	Muscle hypotonia	1.4%
657	Myoclonus	1.4%
658	Myotonia	1.4%
659	Neuralgia	1.4%
660	Paraplegia	1.4%
661	Pseudobulbar Palsy	1.4%
662	Quadriplegia	1.4%
663	Spasm	1.4%
664	Spastic Paraplegia	1.4%
665	Status Epilepticus	1.4%
666	Taste Disorders	1.4%
667	Tremor	1.4%
668	Spina Bifida	1.4%
669	Monoplegia	1.4%
670	Hypokinesia	1.4%
671	Paraparesis	1.4%
672	Bradykinesia	1.4%
673	Waxy flexibility	1.4%
674	Action Tremor	1.4%
675	Resting Tremor	1.4%
676	Dysosmia	1.4%
677	Quadriparesis	1.4%
678	Mercury Poisoning, Nervous System	1.4%
679	Olfaction Disorders	1.4%
680	Myokymia	1.4%
681	Lead Poisoning, Nervous System	1.4%
682	Vestibular Neuronitis	1.4%
683	Somatosensory Disorders	1.4%
684	Neuropathic pain	1.4%
685	Hyperkinesia	1.4%
686	Intention tremor	1.4%
687	Akathisia	1.4%
688	Restlessness	1.4%
689	Psychomotor Agitation	1.4%
690	Prolactinoma	1.4%
691	Growth Hormone-Secreting Pituitary Adenoma	1.4%
692	Williams Syndrome	1.4%
693	Myotonic Dystrophy	1.4%
694	Multiple Sclerosis, Chronic Progressive	1.3%
695	Multiple Sclerosis, Relapsing-Remitting	1.3%
696	Zellweger Syndrome	1.3%
697	Tarsal Tunnel Syndrome	1.3%
698	Cauda Equina Syndrome	1.3%
699	Vision Disorders	1.3%
700	Metamorphopsia	1.3%
701	Visual Impairment	1.3%
702	Fibromyalgia	1.2%
703	Medial Tibial Stress Syndrome	1.2%
704	Facial Hemiatrophy	1.2%
705	Melkersson-Rosenthal Syndrome	1.2%
706	Mitochondrial Myopathies	1.2%
707	Anisocoria	1.2%
708	Confusion	1.2%
709	Facial paralysis	1.2%
710	Lethargy	1.2%
711	Memory Disorders	1.2%
712	Muscle Cramp	1.2%
713	Perceptual Disorders	1.2%
714	Psychomotor Disorders	1.2%
715	Tonic Pupil	1.2%
716	Eosinophilia-Myalgia Syndrome	1.2%
717	Anhedonia	1.2%
718	Disorientation	1.2%
719	Facial Paresis	1.2%
720	Memory Loss	1.2%
721	Hemisensory Neglect	1.2%
722	Dysacusis	1.2%
723	Sleep Bruxism	1.2%
724	Toxoplasmosis, Congenital	1.2%
725	Kartagener Syndrome	1.2%
726	Acoustic Neuroma	1.2%
727	Anencephaly	1.2%
728	Meningocele	1.2%
729	Muscular Atrophy	1.2%
730	Respiratory Paralysis	1.2%
731	Encephalocele	1.2%
732	Malaria, Cerebral	1.2%
733	Tetany	1.2%
734	Gait Apraxia	1.2%
735	Neurocysticercosis	1.2%
736	Nelson Syndrome	1.2%
737	Alstrom Syndrome	1.1%
738	Amyloid Neuropathies, Familial	1.1%
739	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.1%
740	Optic Nerve Glioma	1.1%
741	Carpal Tunnel Syndrome	1.1%
742	Duane Retraction Syndrome	1.1%
743	Consciousness Disorders	1.1%
744	Mental Retardation	1.1%
745	Muscle Weakness	1.1%
746	Depressed Level of Consciousness	1.1%
747	Mental deficiency	1.1%
748	Intellectual Disability	1.1%
749	neurofibroma	1.1%
750	Sciatica	1.1%
751	Mobius Syndrome	1.1%
752	Bell Palsy	1.1%
753	Catatonia	1.1%
754	Herpes Zoster Oticus	1%
755	Familial Periodic Paralysis	1%
756	Aphonia	1%
757	Sleep Deprivation	1%
758	Dysphonia	1%
759	Glycogen storage disease type II	1%
760	Waterhouse-Friderichsen Syndrome	1%
761	Sciatic Neuropathy	1%
762	Ulnar Neuropathies	1%
763	Lesion of Sciatic Nerve	1%
764	Ulnar Neuritis	1%
765	Radial nerve compression	1%
766	Radial Tunnel Syndrome	1%
767	Peroneal Neuropathies	1%
768	Radial Neuropathy	1%
769	Median Neuropathy	1%
770	Sciatic Nerve Palsy	1%
771	Femoral Neuropathy	1%
772	Tibial Neuropathy	1%
773	Ulnar Nerve Palsy	1%
774	Postural Orthostatic Tachycardia Syndrome	1%
775	Radial nerve palsy	1%
776	Myalgia	0.9%
777	Neuronal Ceroid-Lipofuscinoses	0.9%
778	Aicardi's syndrome	0.8%
779	Hoarseness	0.8%
780	Cockayne Syndrome	0.8%
781	Alcohol Withdrawal Delirium	0.8%
782	Esotropia	0.8%
783	Exotropia	0.8%
784	Sleep Apnea Syndromes	0.8%
785	Polymyositis	0.8%
786	Disorders of Excessive Somnolence	0.8%
787	Sleep Initiation and Maintenance Disorders	0.8%
788	Night Terrors	0.8%
789	Somnambulism	0.8%
790	Trigeminal Nerve Disorder	0.8%
791	Transient Insomnia	0.8%
792	Sleep Paralysis	0.8%
793	Chronic Insomnia	0.8%
794	REM Sleep Behavior Disorder	0.8%
795	Hypersomnia	0.8%
796	Classical Lissencephalies and Subcortical Band Heterotopias	0.8%
797	Dermal Sinus	0.8%
798	Dysgeusia	0.8%
799	Formication	0.8%
800	Hyperalgesia	0.8%
801	Hyperesthesia	0.8%
802	Hypesthesia	0.8%
803	Language Disorders	0.8%
804	Numbness	0.8%
805	Paresthesia	0.8%
806	Paraparesis, Spastic	0.8%
807	Spina Bifida Cystica	0.8%
808	Trismus	0.8%
809	Spina Bifida Occulta	0.8%
810	Epilepsia Partialis Continua	0.8%
811	Hypogeusia	0.8%
812	Cubital Tunnel Syndrome	0.8%
813	Meningeal Carcinomatosis	0.8%
814	Brown-Sequard Syndrome	0.8%
815	Lissencephaly	0.8%
816	Polymicrogyria	0.8%
817	Pachygyria	0.8%
818	Schizencephaly	0.8%
819	Lockjaw	0.8%
820	Allodynia	0.8%
821	Lead Poisoning, Nervous System, Childhood	0.8%
822	Lead Poisoning, Nervous System, Adult	0.8%
823	Periventricular Nodular Heterotopia	0.8%
824	Ageusia	0.8%
825	Holoprosencephaly	0.7%
826	Eye Injuries	0.7%
827	Gaucher Disease	0.7%
828	Muscular Dystrophy	0.7%
829	Congenital nystagmus	0.7%
830	Orbital Myositis	0.7%
831	Diplopia	0.7%
832	Muscle Rigidity	0.7%
833	Muscle Spasticity	0.7%
834	Scotoma	0.7%
835	Photophobia	0.7%
836	Cogwheel Rigidity	0.7%
837	Hemifacial Spasm	0.7%
838	Amaurosis	0.7%
839	Blindness	0.7%
840	Nuchal Rigidity	0.7%
841	Pyomyositis	0.7%
842	Agnosia	0.7%
843	Apraxias	0.7%
844	Hallucinations	0.7%
845	Hemianopsia	0.7%
846	Hyperacusis	0.7%
847	Tinnitus	0.7%
848	Visual Agnosia	0.7%
849	Anosognosia	0.7%
850	Wernicke-Korsakoff Syndrome	0.7%
851	Phonophobia	0.7%
852	Hearing Loss	0.7%
853	Sarcopenia	0.7%
854	Optic Atrophy, Hereditary, Leber	0.6%
855	Alexia	0.6%
856	Dyslexia	0.6%
857	Polyradiculopathy	0.6%
858	Amnesia	0.6%
859	Delirium	0.6%
860	Dissociative Amnesia	0.6%
861	Color blindness	0.6%
862	Global Amnesia	0.6%
863	Cri-du-Chat Syndrome	0.6%
864	Down Syndrome	0.6%
865	Trisomy 21	0.6%
866	POEMS Syndrome	0.6%
867	Meningioma	0.6%
868	Microcephaly	0.6%
869	Macrocephaly	0.6%
870	Hypokalemic periodic paralysis	0.6%
871	Porencephaly	0.6%
872	Niemann-Pick Disease, Type C	0.5%
873	Tay-Sachs Disease	0.5%
874	Prader-Willi Syndrome	0.5%
875	Phantom pain	0.5%
876	Phantom Limb Pain	0.5%
877	Neurofibrosarcoma	0.5%
878	Sleep Apnea, Obstructive	0.5%
879	Sleep Apnea, Central	0.5%
880	Narcolepsy	0.5%
881	Trigeminal Neuralgia	0.5%
882	Kleine-Levin Syndrome	0.5%
883	Agraphia	0.5%
884	Anomia	0.5%
885	Cluttering	0.5%
886	Language Development Disorders	0.5%
887	Speech Disorders	0.5%
888	Syncope	0.5%
889	Stupor	0.5%
890	Dysgraphia	0.5%
891	Presyncope	0.5%
892	Dyslalia	0.5%
893	Rubinstein-Taybi Syndrome	0.4%
894	Eye Burns	0.4%
895	Welander Distal Myopathy	0.4%
896	Amaurosis Fugax	0.4%
897	Blindness, Cortical	0.4%
898	Dyscalculia	0.4%
899	Rett Syndrome	0.4%
900	Deafness	0.4%
901	Hearing Loss, Sudden	0.4%
902	Gerstmann Syndrome	0.4%
903	Hearing Loss, Bilateral	0.4%
904	Hearing Loss, High-Frequency	0.4%
905	Hearing Loss, Mixed Conductive-Sensorineural	0.4%
906	Prosopagnosia	0.4%
907	Apraxia, Ideomotor	0.4%
908	Charles Bonnet Syndrome	0.4%
909	Hearing Loss, Unilateral	0.4%
910	Complete Hearing Loss	0.4%
911	Alien Hand Syndrome	0.4%
912	Deaf Mutism	0.4%
913	Dermatomyositis	0.4%
914	Corneal Scar	0.4%
915	Muscular Dystrophy, Duchenne	0.3%
916	Retrograde amnesia	0.3%
917	Amnesia, Anterograde	0.3%
918	Cataplexy	0.3%
919	Aphasia	0.3%
920	Articulation Disorders	0.3%
921	Echolalia	0.3%
922	Stuttering	0.3%
923	Dysphasia	0.3%
924	Fragile X Syndrome	0.3%
925	Mutism	0.3%
926	Selective Mutism	0.3%
927	Dysarthria	0.2%
928	Corneal Perforation	0.2%
929	Mucopolysaccharidosis II	0.2%
930	Alexia, Pure	0.2%

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