MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Supravalvular aortic stenosis

(UMLS:C0003499)

Definition:: A pathological constriction occurring in the region above the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
UMLS ID:: C0003499
MeSH ID:: D021921

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.484.150.535|C14.280.955.249.535

Synonym(s)

Supravalvular aortic stenosis

SUPRAVALVULAR AORTIC STENOSIS

SVAS - Supravalvar aortic stenosis

Supravalvar aortic stenosis

Supravalvular Aortic Stenosis

Supravalvular aorta constricted

aortic stenosis supra valvular

aortic stenosis supravalvar

supra-valvular aortic stenosis

10.

supravalvar aortic stenosis

11.

supravalvular aortic stenosis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Paroxetine	FAERS: 5	US FAERS
2	Sertraline	FAERS: 3	US FAERS
3	Fluoxetine	FAERS: 1	US FAERS
4	Insulin Glargine	FAERS: 1	US FAERS
5	Ondansetron	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Pulmonary Valve Stenosis	49.2%
2	Hypertrophic Cardiomyopathy	36.4%
3	Hypertrophic obstructive cardiomyopathy	36.4%
4	Myocardial Ischemia	33.9%
5	Cardiac Tamponade	33.3%
6	Endocarditis	33.3%
7	Cardiac Arrest	33.3%
8	Heart failure	33.3%
9	Pericardial effusion	33.3%
10	Pericarditis	33.3%
11	Pneumopericardium	33.3%
12	Cor pulmonale	33.3%
13	Ventricular Dysfunction	33.3%
14	Cardiomyopathies	33.3%
15	Pleuropericarditis	33.3%
16	Aortic Valve Insufficiency	32.6%
17	Mitral Valve Insufficiency	32.6%
18	Mitral Valve Stenosis	32.6%
19	Pulmonary Valve Insufficiency	32.6%
20	Tricuspid Valve Insufficiency	32.6%
21	Tricuspid Valve Stenosis	32.6%
22	Cardiomyopathy, Dilated	29.5%
23	Tricuspid Atresia	29.5%
24	Cardiac Output, High	25.4%
25	Myocardial Stunning	25.4%
26	Low Cardiac Output Syndrome	25.4%
27	Cardiomegaly	25%
28	Postpericardiotomy Syndrome	25%
29	Cardiac Hypertrophy	25%
30	Rheumatic Heart Disease	24.7%
31	Heart Block	23.7%
32	Tachycardia	23.7%
33	Tachyarrhythmia	23.7%
34	Arrhythmogenic Right Ventricular Dysplasia	23%
35	Myocardial Reperfusion Injury	22.5%
36	Aortic Valve Prolapse	21.5%
37	Tricuspid Valve Prolapse	21.5%
38	Vascular Diseases	20.9%
39	Coronary heart disease	19.7%
40	Long QT Syndrome	19.7%
41	Myocardial Infarction	19.7%
42	Acute Coronary Syndrome	19.7%
43	Restrictive cardiomyopathy	19.6%
44	Endocardial Fibroelastosis	19.6%
45	Heart Rupture, Post-Infarction	19.6%
46	Myocarditis	19.6%
47	Pericarditis, Constrictive	19.6%
48	Ventricular Dysfunction, Left	19.6%
49	Right Ventricular Dysfunction	19.6%
50	Endomyocardial Fibrosis	19.6%
51	Carditis	19.6%
52	Heart Failure, Systolic	19.6%
53	Heart Failure, Diastolic	19.6%
54	Lown-Ganong-Levine Syndrome	19.4%
55	Ventricular Outflow Obstruction	16.7%
56	Sick Sinus Syndrome	16.6%
57	Carcinoid Heart Disease	16.2%
58	Kounis Syndrome	16%
59	Pregnancy Complications, Cardiovascular	15.8%
60	Cardiovascular Abnormalities	15.8%
61	Bacterial Endocarditis	15.7%
62	Aortic coarctation	15.7%
63	Cor Triatriatum	15.7%
64	Coronary Vessel Anomalies	15.7%
65	Patent ductus arteriosus	15.7%
66	Ebstein Anomaly	15.7%
67	Heart Septal Defects	15.7%
68	Tetralogy of Fallot	15.7%
69	Transposition of Great Vessels	15.7%
70	Hypoplastic Left Heart Syndrome	15.7%
71	Angina Pectoris	15.6%
72	Adams-Stokes Syndrome	15.5%
73	Atrioventricular Block	15.5%
74	Bundle-Branch Block	15.5%
75	Atrial Premature Complexes	15.5%
76	Sinoatrial Block	15.5%
77	Tachycardia, Paroxysmal	15.5%
78	Supraventricular tachycardia	15.5%
79	Tachycardia, Ventricular	15.5%
80	Wolff-Parkinson-White Syndrome	15.5%
81	Tachycardia, Reciprocating	15.5%
82	Aortic Valve Stenosis	14.8%
83	Sinus Arrhythmia	14.8%
84	Atrial Fibrillation	14.8%
85	Atrial Flutter	14.8%
86	Edema, Cardiac	14.8%
87	Ventricular Fibrillation	14.8%
88	Ventricular Flutter	14.8%
89	Parasystole	14.8%
90	Paroxysmal atrial fibrillation	14.8%
91	Bradycardia	14.8%
92	Diabetic Cardiomyopathies	14.8%
93	Cardiomyopathy, Alcoholic	14.6%
94	Sudden Cardiac Death	14.6%
95	Left Ventricular Hypertrophy	14.6%
96	Right Ventricular Hypertrophy	14.6%
97	Chagas Cardiomyopathy	14.6%
98	Coronary Aneurysm	14.3%
99	Dextrocardia	13.1%
100	Coronary Thrombosis	12.9%
101	Coronary Occlusion	12.9%
102	Microvascular Angina	12.9%
103	Coronary Stenosis	12.9%
104	ST segment elevation myocardial infarction	12.9%
105	Takotsubo Cardiomyopathy	12.9%
106	Coronary Artery Disease	12.9%
107	Romano-Ward Syndrome	12.9%
108	Dyspnea, Paroxysmal	11.8%
109	Tachycardia, Atrioventricular Nodal Reentry	11.5%
110	Tachycardia, Ectopic Atrial	11.5%
111	Tachycardia, Ectopic Junctional	11.5%
112	Sinus Tachycardia	11.5%
113	Torsades de Pointes	11.5%
114	Accelerated Idioventricular Rhythm	11.5%
115	Aneurysm	11.1%
116	Angiomatosis	11.1%
117	Aortic Diseases	11.1%
118	Arterial Occlusive Diseases	11.1%
119	Hyperemia	11.1%
120	Hypotension	11.1%
121	Superior Vena Cava Syndrome	11.1%
122	Telangiectasis	11.1%
123	Vasculitis	11.1%
124	Venous Insufficiency	11.1%
125	Peripheral Vascular Diseases	11.1%
126	Embolism and Thrombosis	11.1%
127	Angiodysplasia	11.1%
128	Capillary Leak Syndrome	11.1%
129	Prehypertension	11.1%
130	Shock, Cardiogenic	10.4%
131	Aortopulmonary Septal Defect	10.3%
132	Double Outlet Right Ventricle	10.3%
133	Endocardial Cushion Defects	10.3%
134	Myocardial bridging	10.3%
135	Aorticopulmonary Septal Defect	10.3%
136	Angina, Unstable	10.3%
137	Noonan Syndrome	9.9%
138	Aortic Aneurysm	9.8%
139	Aortitis	9.8%
140	Leriche Syndrome	9.8%
141	Periphlebitis	9.8%
142	Phlebitis	9.8%
143	Thromboangiitis Obliterans	9.8%
144	Supravalvular aortic stenosis	9.7%
145	Sinus Arrest, Cardiac	9.7%
146	Coronary Restenosis	9.6%
147	Embolism, Amniotic Fluid	9.3%
148	Marfan Syndrome	8.9%
149	Vascular System Injuries	8.8%
150	Retinal Vein Occlusion	8.7%
151	Compartment syndromes	8.5%
152	Hepatic Veno-Occlusive Disease	8.5%
153	Peliosis Hepatis	8.5%
154	Varicocele	8.5%
155	Subacute Bacterial Endocarditis	8.4%
156	Cerebrovascular Disorders	8.3%
157	Diabetic Angiopathies	8.3%
158	Reperfusion Injury	8.3%
159	Splenic Infarction	8.3%
160	Cerebrovascular Insufficiency	8.3%
161	Vascular Neoplasms	8.3%
162	Spinal Cord Vascular Diseases	8.3%
163	Vasoplegia	8.3%
164	Hemorrhoids	8.3%
165	Thoracic Outlet Syndrome	8.3%
166	Postphlebitic Syndrome	8.1%
167	Arteriovenous fistula	8.1%
168	Malignant Atrophic Papulosis	7.9%
169	Shwartzman Phenomenon	7.8%
170	May-Thurner Syndrome	7.8%
171	Truncus Arteriosus, Persistent	7.7%
172	Angina Pectoris, Variant	7.6%
173	Thrombophlebitis	7.1%
174	Hand-Arm Vibration Syndrome	6.9%
175	Blue Toe Syndrome	6.9%
176	Optic Neuropathy, Ischemic	6.8%
177	Anterior Ischemic Optic Neuropathy	6.8%
178	Mesenteric vascular insufficiency	6.8%
179	Scimitar Syndrome	6.8%
180	Angioedema	6.6%
181	Aortic Rupture	6.6%
182	Colitis, Ischemic	6.6%
183	Aneurysm, Dissecting	6.5%
184	Arteriosclerosis	6.5%
185	Arteritis	6.5%
186	Embolism	6.5%
187	Erythromelalgia	6.5%
188	Fibromuscular Dysplasia	6.5%
189	Malignant Hypertension	6.5%
190	Raynaud Disease	6.5%
191	Thromboembolism	6.5%
192	Thrombosis	6.5%
193	Essential Hypertension	6.5%
194	Aneurysm, Ruptured	6.5%
195	Iliac Aneurysm	6.5%
196	Pulmonary artery stenosis	6.5%
197	White Coat Hypertension	6.5%
198	Systemic Vasculitis	6.5%
199	Embolus	6.5%
200	Intracranial Embolism and Thrombosis	6.5%
201	Carotid Stenosis	6.5%
202	Intracranial Aneurysm	6.5%
203	Aortic Aneurysm, Abdominal	6.5%
204	Aortic Aneurysm, Thoracic	6.5%
205	Moyamoya Disease	6%
206	Carotid Artery Thrombosis	5.9%
207	Vasculitis, Central Nervous System	5.7%
208	Polyarteritis Nodosa	5.2%
209	Takayasu Arteritis	5.2%
210	Turner Syndrome	5.2%
211	Intracranial Arteriosclerosis	5.1%
212	Cerebral Atherosclerosis	5.1%
213	Cerebral Arteriosclerosis	5.1%
214	Retinal Artery Occlusion	5%
215	Retinal Vasculitis	5%
216	Hypertensive Retinopathy	5%
217	Anterior Compartment Syndrome	4.9%
218	Vasculitis, Leukocytoclastic, Cutaneous	4.9%
219	Gastric Antral Vascular Ectasia	4.9%
220	Abdominal Compartment Syndrome	4.9%
221	Carotid Artery Diseases	4.9%
222	Brain Ischemia	4.9%
223	Ectopia Cordis	4.9%
224	Hypotension, Orthostatic	4.9%
225	Cerebrovascular accident	4.9%
226	Varicose Ulcer	4.9%
227	Vasospasm, Intracranial	4.9%
228	Spinal Cord Ischemia	4.9%
229	Intracranial Arterial Diseases	4.9%
230	Primary Graft Dysfunction	4.9%
231	Single umbilical artery	4.9%
232	Post-Exercise Hypotension	4.9%
233	Kearns-Sayre syndrome	4.8%
234	Cerebral Thrombosis	4.5%
235	Intracranial Embolism	4.5%
236	Intracranial Thrombosis	4.5%
237	Giant Cell Arteritis	4.3%
238	Temporal Arteritis	4.3%
239	Arteriosclerosis Obliterans	4.3%
240	Atherosclerosis	4.3%
241	Air Embolism	4.3%
242	Endarteritis	4.3%
243	Venous Thrombosis	4.3%
244	Deep Vein Thrombosis	4.3%
245	Venous Thromboembolism	4.3%
246	Brain Infarction	4.3%
247	CREST Syndrome	4%
248	Mesenteric Vascular Occlusion	4%
249	Mucocutaneous Lymph Node Syndrome	4%
250	Diabetic Retinopathy	4%
251	Sturge-Weber Syndrome	4%
252	Livedo Reticularis	3.9%
253	Renal hypertension	3.9%
254	Renal Artery Obstruction	3.9%
255	Renal Artery Stenosis	3.9%
256	Hemangioma, Cavernous	3.9%
257	Basal Ganglia Cerebrovascular Disease	3.9%
258	Vascular Headaches	3.9%
259	Scurvy	3.9%
260	Kartagener Syndrome	3.8%
261	Vertebral Artery Dissection	3.7%
262	Subarachnoid Hemorrhage, Traumatic	3.6%
263	Carotid Artery, Internal, Dissection	3.6%
264	Sinus Thrombosis, Intracranial	3.5%
265	Lemierre Syndrome	3.5%
266	Dural Arteriovenous Fistula	3.3%
267	Intermittent Claudication	3.3%
268	Pulmonary Embolism	3.3%
269	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.3%
270	Ischemic contracture	3.3%
271	Angioedemas, Hereditary	3.3%
272	Cryoglobulinemia	3.3%
273	Leukomalacia, Periventricular	3.3%
274	No-Reflow Phenomenon	3.3%
275	Carotid Artery Injuries	3.2%
276	Diabetic Foot	3.2%
277	Cerebral Arterial Diseases	3.2%
278	Vertebrobasilar Insufficiency	3.2%
279	Anterior Spinal Artery Syndrome	3.2%
280	Basilar Artery Stenosis	3.2%
281	Vertebral Artery Stenosis	3.2%
282	Intracranial Hemorrhage, Hypertensive	3.2%
283	Transient Cerebral Ischemia	3.2%
284	Cerebral Infarction	3.2%
285	Brain Stem Infarctions	3.2%
286	Infarction, Middle Cerebral Artery	3.2%
287	Infarction, Anterior Cerebral Artery	3.2%
288	Infarction, Posterior Cerebral Artery	3.2%
289	Cavernous Sinus Thrombosis	3%
290	Sagittal Sinus Thrombosis	3%
291	Basal Ganglia Hemorrhage	2.8%
292	Shy-Drager Syndrome	2.8%
293	Purpura, Hyperglobulinemic	2.8%
294	Lateral Medullary Syndrome	2.6%
295	Hypertension, Renovascular	2.6%
296	Subarachnoid Hemorrhage	2.6%
297	Hypoxia-Ischemia, Brain	2.6%
298	Cerebral Hemorrhage	2.6%
299	Hereditary Angioedema Type III	2.6%
300	Hereditary Angioedema Types I and II	2.6%
301	Behcet Syndrome	2.5%
302	Hepatic Vein Thrombosis	2.5%
303	Budd-Chiari Syndrome	2.5%
304	Waldenstrom Macroglobulinemia	2.5%
305	Multiple Myeloma	2.5%
306	Williams Syndrome	2.4%
307	Pulmonary Infarction	2.4%
308	Subclavian Steal Syndrome	2.4%
309	Ataxia Telangiectasia	2.2%
310	Pseudoxanthoma Elasticum	2.2%
311	Putaminal Hemorrhage	2.2%
312	Pituitary Apoplexy	2.2%
313	Dementia, Vascular	2.1%
314	Lupus Vasculitis, Central Nervous System	2%
315	Granulomatosis with polyangiitis	2%
316	Cerebral Amyloid Angiopathy	1.9%
317	Rheumatoid Vasculitis	1.9%
318	Hematoma, Subdural	1.2%
319	Hematoma, Epidural, Cranial	1.2%
320	MELAS Syndrome	1.2%
321	Brain Hemorrhage, Traumatic	1.1%
322	Hematoma, Subdural, Intracranial	1%
323	Hematoma, Subdural, Chronic	1%
324	Hematoma, Subdural, Acute	1%
325	Fabry Disease	0.9%

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