MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Malignant Atrophic Papulosis

(UMLS:C0221011)

Definition:: Variously described as a vasculopathy, endovasculitis, or occlusive arteriopathy, this condition occurs in a benign cutaneous form and a lethal multiorgan systemic variant. It is characterized by a narrowing and occlusion of the lumen of small to medium-sized blood vessels, leading to ischemia and infarction in the involved organ systems. The etiology and pathophysiology are unknown.
UMLS ID:: C0221011
MeSH ID:: D054853

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.137.520|C14.907.940.530

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.862.457

Synonym(s)

Malignant Atrophic Papulosis

CUTANEOINTESTINAL SYNDROME

DEGOS DISEASE

Degos

Degos Disease

Degos disease

Degos' disease

Erythrokeratoderma en cocarde (Degos)

Erythrokeratoderma en cocardes

10.

Erythrokeratoderma en cocardes (Degos syndrome)

11.

KOEHLMEIER-DEGOS SYNDROME

12.

Kohlmeier-Degos disease

13.

Kohlmeier-Degos syndrome

14.

Lethal cutaneous and gastrointestinal arteriolar thrombosis

15.

MALIGNANT ATROPHIC PAPULOSIS

16.

MAP - malignant atrophic papulosis

17.

Maladie de Degos

18.

Malignant atrophic papulosis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Oxymorphone	FAERS: 2	US FAERS
2	treprostinil	FAERS: 2	US FAERS
3	Dipyridamole	FAERS: 1	US FAERS
4	Fingolimod Hydrochloride	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Thromboangiitis Obliterans	53.3%
2	Polyarteritis Nodosa	48.4%
3	Aortitis	42.7%
4	Leriche Syndrome	42.7%
5	Periphlebitis	42.7%
6	Phlebitis	42.7%
7	Takayasu Arteritis	41.8%
8	Mucocutaneous Lymph Node Syndrome	38.2%
9	Shwartzman Phenomenon	35.4%
10	Giant Cell Arteritis	34.7%
11	Temporal Arteritis	34.7%
12	Thrombophlebitis	34.3%
13	Arteriosclerosis	33.3%
14	Arteritis	33.3%
15	Fibromuscular Dysplasia	33.3%
16	Pulmonary artery stenosis	33.3%
17	Systemic Vasculitis	33.3%
18	Myocardial Ischemia	32.9%
19	Aortic Aneurysm	32%
20	Carotid Stenosis	31.8%
21	Angioedema	31.7%
22	Aneurysm	30.5%
23	Angiomatosis	30.5%
24	Aortic Diseases	30.5%
25	Hyperemia	30.5%
26	Hypotension	30.5%
27	Superior Vena Cava Syndrome	30.5%
28	Telangiectasis	30.5%
29	Venous Insufficiency	30.5%
30	Peripheral Vascular Diseases	30.5%
31	Embolism and Thrombosis	30.5%
32	Angiodysplasia	30.5%
33	Capillary Leak Syndrome	30.5%
34	Prehypertension	30.5%
35	Moyamoya Disease	29.7%
36	Coronary Artery Disease	29.5%
37	Livedo Reticularis	28.9%
38	Pyoderma Gangrenosum	28.9%
39	Retinal Vein Occlusion	28.7%
40	Behcet Syndrome	28.5%
41	Postphlebitic Syndrome	27.8%
42	Retinal Artery Occlusion	27%
43	Retinal Vasculitis	27%
44	Vasculitis, Central Nervous System	26.8%
45	Vasculitis, Leukocytoclastic, Cutaneous	26.7%
46	Myocardial Reperfusion Injury	26.6%
47	Coronary Aneurysm	26.4%
48	Intracranial Arteriosclerosis	26.2%
49	Cerebral Atherosclerosis	26.2%
50	Cerebral Arteriosclerosis	26.2%
51	Aortic Rupture	25.6%
52	Vascular System Injuries	25.4%
53	Arteriosclerosis Obliterans	24.8%
54	Atherosclerosis	24.8%
55	Endarteritis	24.8%
56	Blue Toe Syndrome	24.7%
57	Compartment syndromes	24.7%
58	Hepatic Veno-Occlusive Disease	24.7%
59	Peliosis Hepatis	24.7%
60	Varicocele	24.7%
61	Cerebrovascular Disorders	24.3%
62	Diabetic Angiopathies	24.3%
63	Reperfusion Injury	24.3%
64	Splenic Infarction	24.3%
65	Cerebrovascular Insufficiency	24.3%
66	Vascular Neoplasms	24.3%
67	Spinal Cord Vascular Diseases	24.3%
68	Vasoplegia	24.3%
69	Hemorrhoids	24.2%
70	Thoracic Outlet Syndrome	24.2%
71	Carotid Artery Thrombosis	23.7%
72	Aortic Aneurysm, Abdominal	23.7%
73	Aortic Aneurysm, Thoracic	23.7%
74	Intracranial Embolism and Thrombosis	23.1%
75	Intracranial Aneurysm	23%
76	Coronary Thrombosis	23%
77	Mesenteric Vascular Occlusion	22.5%
78	Renal Artery Obstruction	22.1%
79	Renal Artery Stenosis	22.1%
80	Arteriovenous fistula	21.9%
81	Varicose Ulcer	21.9%
82	Coronary heart disease	21.3%
83	Myocardial Infarction	21.3%
84	Acute Coronary Syndrome	21.3%
85	Hand-Arm Vibration Syndrome	20.9%
86	Optic Neuropathy, Ischemic	20.5%
87	Anterior Ischemic Optic Neuropathy	20.5%
88	Mesenteric vascular insufficiency	20.5%
89	Intermittent Claudication	20.1%
90	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	20.1%
91	Aneurysm, Dissecting	20%
92	Embolism	20%
93	Erythromelalgia	20%
94	Malignant Hypertension	20%
95	Raynaud Disease	20%
96	Thromboembolism	20%
97	Thrombosis	20%
98	Essential Hypertension	20%
99	Aneurysm, Ruptured	20%
100	Iliac Aneurysm	20%
101	White Coat Hypertension	20%
102	Embolus	20%
103	Colitis, Ischemic	19.9%
104	Angioedemas, Hereditary	19.7%
105	Lemierre Syndrome	19.7%
106	CREST Syndrome	19.6%
107	Urticaria	18.7%
108	Hereditary Angioedema Type III	18.3%
109	Hereditary Angioedema Types I and II	18.3%
110	Pseudoxanthoma Elasticum	18.1%
111	Kounis Syndrome	18%
112	Cerebral Thrombosis	17.9%
113	Intracranial Embolism	17.9%
114	Intracranial Thrombosis	17.9%
115	May-Thurner Syndrome	17.7%
116	Angina Pectoris	17.6%
117	Heart Diseases	17.5%
118	Embolism, Amniotic Fluid	16.8%
119	Brain Infarction	16.7%
120	Scimitar Syndrome	16.6%
121	Lupus Erythematosus, Cutaneous	16.4%
122	Panniculitis	16.4%
123	Systemic Scleroderma	16.4%
124	Morphea	16.4%
125	Hypertensive Retinopathy	16.2%
126	Acne Vulgaris	16%
127	Anterior Compartment Syndrome	16%
128	Contact Dermatitis	16%
129	Eczema	16%
130	Erythema Multiforme	16%
131	Intertrigo	16%
132	Neurodermatitis	16%
133	Rhinophyma	16%
134	Perioral Dermatitis	16%
135	Gastric Antral Vascular Ectasia	16%
136	Acne	16%
137	Abdominal Compartment Syndrome	16%
138	Carotid Artery Diseases	15.9%
139	Brain Ischemia	15.9%
140	Hypotension, Orthostatic	15.9%
141	Cerebrovascular accident	15.9%
142	Vasospasm, Intracranial	15.9%
143	Spinal Cord Ischemia	15.9%
144	Intracranial Arterial Diseases	15.9%
145	Primary Graft Dysfunction	15.9%
146	Post-Exercise Hypotension	15.9%
147	Coronary Occlusion	15.8%
148	Microvascular Angina	15.8%
149	Coronary Stenosis	15.8%
150	ST segment elevation myocardial infarction	15.8%
151	Subarachnoid Hemorrhage, Traumatic	15.5%
152	Carotid Artery, Internal, Dissection	15.5%
153	Sinus Thrombosis, Intracranial	15.4%
154	Arterial Occlusive Diseases	15.3%
155	Breast Diseases	15.3%
156	Dermatitis	15.3%
157	Exanthema	15.3%
158	Facial Dermatoses	15.3%
159	Hair Diseases	15.3%
160	Hand Dermatoses	15.3%
161	keratoacanthoma	15.3%
162	Keratosis	15.3%
163	Nail Diseases	15.3%
164	Photosensitivity Disorders	15.3%
165	Prurigo	15.3%
166	Pyoderma	15.3%
167	Rosacea	15.3%
168	Sebaceous Gland Diseases	15.3%
169	Skin Diseases, Vesiculobullous	15.3%
170	Skin Ulcer	15.3%
171	Sweat Gland Diseases	15.3%
172	Vasculitis	15.3%
173	Skin Diseases, Papulosquamous	15.3%
174	Acneiform Eruptions	15.3%
175	Ocular Rosacea	15.3%
176	Subcorneal pustular dermatosis	15.3%
177	Erythematotelangiectatic Rosacea	15.3%
178	Papulopustular Rosacea	15.3%
179	Chronic Actinic Dermatitis	15.3%
180	Dermatitis, Atopic	15%
181	Epidermolysis Bullosa	15%
182	Infarction, Middle Cerebral Artery	15%
183	Infarction, Anterior Cerebral Artery	15%
184	Infarction, Posterior Cerebral Artery	15%
185	Air Embolism	14.9%
186	Venous Thrombosis	14.9%
187	Deep Vein Thrombosis	14.9%
188	Venous Thromboembolism	14.9%
189	Vertebral Artery Dissection	14.8%
190	Dermatitis, Phototoxic	14.8%
191	Pityriasis Lichenoides et Varioliformis Acuta	14.8%
192	Pityriasis Lichenoides	14.8%
193	Diabetic Foot	14.8%
194	Phototoxicity	14.8%
195	Xeroderma Pigmentosum	14.6%
196	Cavernous Sinus Thrombosis	14.2%
197	Sagittal Sinus Thrombosis	14.2%
198	Pregnancy Complications, Cardiovascular	14.1%
199	Cardiovascular Abnormalities	14.1%
200	Foot Ulcer	13.9%
201	Cerebral Infarction	13.9%
202	Brain Stem Infarctions	13.9%
203	Granulomatosis with polyangiitis	13.8%
204	Rheumatoid Vasculitis	13.6%
205	Dermatitis Herpetiformis	13.5%
206	Diabetic Retinopathy	13.4%
207	Sturge-Weber Syndrome	13.4%
208	Acrodermatitis	13.3%
209	Sebaceous Gland Neoplasms	13.3%
210	Porokeratosis	13.3%
211	Malignant Atrophic Papulosis	13.3%
212	Gianotti-Crosti Syndrome	13.3%
213	Keratoderma, Palmoplantar	13.3%
214	Renal hypertension	13.3%
215	Panniculitis, Lupus Erythematosus	13.2%
216	Hemangioma, Cavernous	13.2%
217	Shock, Cardiogenic	13.2%
218	Basal Ganglia Cerebrovascular Disease	13.2%
219	Vascular Headaches	13.2%
220	Scurvy	13.1%
221	Carotid Artery Injuries	13.1%
222	Coronary Restenosis	13.1%
223	Angina, Unstable	13.1%
224	Dementia, Vascular	13%
225	Necrobiosis Lipoidica Diabeticorum	12.8%
226	Foot Diseases	12.7%
227	Dermatitis, Photoallergic	12.6%
228	Lateral Medullary Syndrome	12.4%
229	Skin Abnormalities	12.3%
230	Skin Diseases, Infectious	12.3%
231	Skin Neoplasms	12.3%
232	Pigmentation Disorders	12.3%
233	Lipomatosis	12.2%
234	Pruritus	12.2%
235	Erythema	12.2%
236	Necrolytic Migratory Erythema	12.2%
237	Cutaneous Fistula	12.2%
238	Nephrogenic Fibrosing Dermopathy	12.2%
239	Nephrogenic Systemic Fibrosis	12.2%
240	Lupus Vasculitis, Central Nervous System	12.1%
241	Pulmonary Embolism	12.1%
242	No-Reflow Phenomenon	11.9%
243	Dermatitis, Irritant	11.8%
244	Acne Conglobata	11.8%
245	Basal Ganglia Hemorrhage	11.8%
246	Cerebral Arterial Diseases	11.8%
247	Vertebrobasilar Insufficiency	11.8%
248	Anterior Spinal Artery Syndrome	11.8%
249	Basilar Artery Stenosis	11.8%
250	Vertebral Artery Stenosis	11.8%
251	Intracranial Hemorrhage, Hypertensive	11.8%
252	Transient Cerebral Ischemia	11.8%
253	Erythema Induratum	11.6%
254	Xeroderma	11.5%
255	Dermatomyositis	11.5%
256	Urticaria Pigmentosa	11.5%
257	Ischemic contracture	11.4%
258	Tricuspid Atresia	11.4%
259	Arrhythmogenic Right Ventricular Dysplasia	11.4%
260	Cryoglobulinemia	11.3%
261	Leukomalacia, Periventricular	11.3%
262	Angina Pectoris, Variant	10.8%
263	Aortic Valve Stenosis	10.7%
264	Cardiomyopathy, Dilated	10.7%
265	Lupus Erythematosus, Discoid	10.7%
266	Pulmonary Valve Stenosis	10.7%
267	Scleroderma, Limited	10.7%
268	Dermatitis, Occupational	10.2%
269	Cardiac Tamponade	10.2%
270	Endocarditis	10.2%
271	Cardiac Arrest	10.2%
272	Heart failure	10.2%
273	Pericardial effusion	10.2%
274	Pericarditis	10.2%
275	Pneumopericardium	10.2%
276	Cor pulmonale	10.2%
277	Ventricular Outflow Obstruction	10.2%
278	Ventricular Dysfunction	10.2%
279	Cardiomyopathies	10.2%
280	Pleuropericarditis	10.2%
281	Putaminal Hemorrhage	10.2%
282	Cutis Laxa	10.1%
283	Mastocytosis	10.1%
284	Erythema Infectiosum	10%
285	Hepatic Vein Thrombosis	10%
286	Budd-Chiari Syndrome	10%
287	Anhidrosis	10%
288	Cholesteatoma	10%
289	Pressure Ulcer	10%
290	Ectodermal Dysplasia	10%
291	Exanthema Subitum	10%
292	Folliculitis	10%
293	Foot Dermatoses	10%
294	Gynecomastia	10%
295	Hypertrichosis	10%
296	Hypohidrosis	10%
297	Hypotrichosis	10%
298	Leg Ulcer	10%
299	Miliaria	10%
300	Parakeratosis	10%
301	Parapsoriasis	10%
302	Pityriasis	10%
303	Psoriasis	10%
304	Sweet Syndrome	10%
305	Hidradenitis	10%
306	Onycholysis	10%
307	Miliaria Rubra	10%
308	Hyperpigmentation	10%
309	Lichenoid Eruptions	10%
310	Chloracne	10%
311	Aplasia Cutis Congenita	10%
312	Pulmonary Infarction	9.9%
313	Dermatitis, Allergic Contact	9.9%
314	Erythema Nodosum	9.9%
315	Shy-Drager Syndrome	9.9%
316	Papillon-Lefevre Disease	9.8%
317	Purpura, Hyperglobulinemic	9.8%
318	Toxic Epidermal Necrolysis	9.8%
319	Stevens-Johnson Syndrome	9.8%
320	Hypertension, Renovascular	9.8%
321	Subarachnoid Hemorrhage	9.8%
322	Hypoxia-Ischemia, Brain	9.8%
323	Cerebral Hemorrhage	9.8%
324	Diaper Rash	9.8%
325	Subclavian Steal Syndrome	9.8%
326	Bacterial Endocarditis	9.7%
327	Tinea Capitis	9.1%
328	Onychomycosis	9.1%
329	Heart Block	8.9%
330	Tachycardia	8.9%
331	Tachyarrhythmia	8.9%
332	Aortic coarctation	8.8%
333	Cor Triatriatum	8.8%
334	Coronary Vessel Anomalies	8.8%
335	Patent ductus arteriosus	8.8%
336	Ebstein Anomaly	8.8%
337	Heart Septal Defects	8.8%
338	Tetralogy of Fallot	8.8%
339	Transposition of Great Vessels	8.8%
340	Hypoplastic Left Heart Syndrome	8.8%
341	Waldenstrom Macroglobulinemia	8.8%
342	Multiple Myeloma	8.8%
343	Connective Tissue Diseases	8.8%
344	Hyperkeratosis, Epidermolytic	8.6%
345	Ecthyma	8.6%
346	Hypertrophic Cardiomyopathy	8.6%
347	Hypertrophic obstructive cardiomyopathy	8.6%
348	Pituitary Apoplexy	8.5%
349	Granuloma Annulare	8.3%
350	Ichthyosis, X-Linked	8.2%
351	Cardiac Output, High	8.2%
352	Myocardial Stunning	8.2%
353	Low Cardiac Output Syndrome	8.2%
354	Sjogren-Larsson Syndrome	8.2%
355	Noonan Syndrome	8.1%
356	Cerebral Amyloid Angiopathy	8.1%
357	Acantholysis	8.1%
358	Breast Cyst	8.1%
359	Cardiomegaly	8.1%
360	Actinic keratosis	8.1%
361	Pemphigoid, Benign Mucous Membrane	8.1%
362	Pemphigus	8.1%
363	Piedra	8.1%
364	Postpericardiotomy Syndrome	8.1%
365	Sunburn	8.1%
366	Cardiac Hypertrophy	8.1%
367	Ataxia Telangiectasia	8.1%
368	Rheumatic Heart Disease	8%
369	Argyria	8%
370	Hirsutism	8%
371	Lactation Disorder	8%
372	Mastitis	8%
373	Adiposis Dolorosa	7.9%
374	Pruritus Vulvae	7.9%
375	Mastocytoma	7.9%
376	Pruritus Ani	7.9%
377	Supravalvular aortic stenosis	7.9%
378	Lown-Ganong-Levine Syndrome	7.9%
379	Dextrocardia	7.6%
380	Long QT Syndrome	7.6%
381	Lichen Planus	7.4%
382	Melanosis	7.4%
383	Chloasma	7.4%
384	Pityriasis Rosea	7.4%
385	Pityriasis Rubra Pilaris	7.4%
386	Vitiligo	7.4%
387	Lichen Nitidus	7.4%
388	Marfan Syndrome	7.4%
389	Hidradenitis Suppurativa	7.4%
390	Sick Sinus Syndrome	7.3%
391	Albinism	7%
392	Erythema Chronicum Migrans	6.9%
393	Dermatomycoses	6.7%
394	Skin Diseases, Bacterial	6.7%
395	Tinea Pedis	6.7%
396	Aortic Valve Insufficiency	6.7%
397	Restrictive cardiomyopathy	6.7%
398	Drug Eruptions	6.7%
399	Endocardial Fibroelastosis	6.7%
400	Heart Rupture, Post-Infarction	6.7%
401	Lipodystrophy	6.7%
402	Mitral Valve Insufficiency	6.7%
403	Mitral Valve Stenosis	6.7%
404	Myocarditis	6.7%
405	Pericarditis, Constrictive	6.7%
406	Pulmonary Valve Insufficiency	6.7%
407	Tricuspid Valve Insufficiency	6.7%
408	Tricuspid Valve Stenosis	6.7%
409	Ventricular Dysfunction, Left	6.7%
410	Right Ventricular Dysfunction	6.7%
411	Endomyocardial Fibrosis	6.7%
412	Carditis	6.7%
413	Heart Failure, Systolic	6.7%
414	Heart Failure, Diastolic	6.7%
415	Adams-Stokes Syndrome	6.6%
416	Atrioventricular Block	6.6%
417	Bundle-Branch Block	6.6%
418	Atrial Premature Complexes	6.6%
419	Sinoatrial Block	6.6%
420	Tachycardia, Paroxysmal	6.6%
421	Supraventricular tachycardia	6.6%
422	Tachycardia, Ventricular	6.6%
423	Wolff-Parkinson-White Syndrome	6.6%
424	Tachycardia, Reciprocating	6.6%
425	Aortopulmonary Septal Defect	6.5%
426	Double Outlet Right Ventricle	6.5%
427	Endocardial Cushion Defects	6.5%
428	Myocardial bridging	6.5%
429	Aorticopulmonary Septal Defect	6.5%
430	Acanthosis Nigricans	6.2%
431	Alopecia Areata	6.2%
432	Lentigo	6.2%
433	Alopecia	6%
434	Sweating, Gustatory	6%
435	Androgenetic Alopecia	6%
436	Auriculotemporal Syndrome	6%
437	Lice Infestations	6%
438	Breast Neoplasms, Male	6%
439	Triple Negative Breast Neoplasms	6%
440	Galactorrhea	5.9%
441	Mycetoma	5.9%
442	Nail-Patella Syndrome	5.8%
443	Porphyrias, Hepatic	5.8%
444	Subacute Bacterial Endocarditis	5.8%
445	Carcinoid Heart Disease	5.6%
446	Romano-Ward Syndrome	5.6%
447	Tachycardia, Atrioventricular Nodal Reentry	5.4%
448	Tachycardia, Ectopic Atrial	5.4%
449	Tachycardia, Ectopic Junctional	5.4%
450	Sinus Tachycardia	5.4%
451	Torsades de Pointes	5.4%
452	Accelerated Idioventricular Rhythm	5.4%
453	Truncus Arteriosus, Persistent	5.4%
454	Hematoma, Subdural	5.4%
455	Hematoma, Epidural, Cranial	5.4%
456	Sinus Arrhythmia	5.3%
457	Atrial Fibrillation	5.3%
458	Atrial Flutter	5.3%
459	Edema, Cardiac	5.3%
460	Ventricular Fibrillation	5.3%
461	Ventricular Flutter	5.3%
462	Parasystole	5.3%
463	Paroxysmal atrial fibrillation	5.3%
464	Bradycardia	5.3%
465	Diabetic Cardiomyopathies	5.3%
466	Cardiomyopathy, Alcoholic	5.3%
467	Ectopia Cordis	5.3%
468	Sudden Cardiac Death	5.3%
469	Left Ventricular Hypertrophy	5.3%
470	Right Ventricular Hypertrophy	5.3%
471	Single umbilical artery	5.3%
472	Chagas Cardiomyopathy	5.3%
473	Collagen Diseases	5.1%
474	Mixed Connective Tissue Disease	5.1%
475	Mucinoses	5.1%
476	Larva Migrans	5%
477	Leishmaniasis	5%
478	Molluscum Contagiosum	5%
479	Lichen Planus, Oral	5%
480	Onchocerciasis	5%
481	Aortic Valve Prolapse	5%
482	Tricuspid Valve Prolapse	5%
483	Takotsubo Cardiomyopathy	5%
484	Chromoblastomycosis	4.9%
485	Dermatophytosis	4.9%
486	Sporotrichosis	4.9%
487	Tinea	4.9%
488	Tinea Versicolor	4.9%
489	Trichophytosis	4.9%
490	Hyalohyphomycosis	4.9%
491	Acute Generalized Exanthematous Pustulosis	4.9%
492	Brain Hemorrhage, Traumatic	4.9%
493	MELAS Syndrome	4.9%
494	Hematoma, Subdural, Intracranial	4.8%
495	Hematoma, Subdural, Chronic	4.8%
496	Hematoma, Subdural, Acute	4.8%
497	Dyspnea, Paroxysmal	4.4%
498	Warts	4.3%
499	Candidiasis, Chronic Mucocutaneous	4.2%
500	Cutaneous Candidiasis	4.2%
501	Cartilage Diseases	4.2%
502	Erysipelas	4.2%
503	Rheumatism	4.2%
504	Serum Sickness	4.2%
505	Staphylococcal Skin Infections	4.2%
506	Chondromalacia	4.2%
507	Variegate Porphyria	4.2%
508	Acute intermittent porphyria	4.2%
509	Porphyria Cutanea Tarda	4.2%
510	Erythrasma	4.2%
511	Carcinoma, Lobular	4.2%
512	Arthritis, Psoriatic	4.2%
513	Leishmaniasis, Cutaneous	4.1%
514	Lupus Erythematosus, Systemic	4.1%
515	Overlap syndrome	4.1%
516	Eczema Herpeticum	4.1%
517	Fusariosis	4.1%
518	Sinus Arrest, Cardiac	3.9%
519	Fabry Disease	3.8%
520	Dural Arteriovenous Fistula	3.8%
521	Epidermodysplasia Verruciformis	3.5%
522	Herpes Labialis	3.5%
523	Staphylococcal Scalded Skin Syndrome	3.5%
524	Dupuytren Contracture	3.3%
525	Scleromyxedema	3.3%
526	Blastomycosis	3.3%
527	HIV-Associated Lipodystrophy Syndrome	3.3%
528	Turner Syndrome	3.2%
529	Peutz-Jeghers Syndrome	3.2%
530	carbuncle	3.1%
531	Condylomata Acuminata	3.1%
532	Furunculosis	3.1%
533	furuncle	3.1%
534	Impetigo	3%
535	Rhinoscleroma	3%
536	Menkes Kinky Hair Syndrome	3%
537	Cellulitis	2.9%
538	Mesenteric Panniculitis	2.7%
539	Panniculitis, Peritoneal	2.7%
540	Tietze's Syndrome	2.7%
541	Orbital Cellulitis	2.7%
542	Myxoid cyst	2.7%
543	Kartagener Syndrome	2.7%
544	Myxedema	2.7%
545	Williams Syndrome	2.4%
546	Osteochondritis	2.3%
547	Polymyalgia Rheumatica	2.3%
548	Osteogenesis Imperfecta	2.2%
549	Keloid	2.2%
550	Kearns-Sayre syndrome	2%
551	Homocystinuria	2%
552	Rheumatoid Arthritis	1.9%
553	Juvenile arthritis	1.9%
554	Lupus Nephritis	1.9%
555	Laryngomalacia	1.7%
556	Pectus carinatum	1.7%
557	Rheumatoid Nodule	1.6%
558	Felty Syndrome	1.4%
559	Bronchomalacia	1.4%
560	Tracheomalacia	1.4%
561	Mucopolysaccharidosis III	1.2%
562	Sicca Syndrome	1.1%
563	Sjogren's Syndrome	1.1%
564	Mucopolysaccharidosis II	0.9%

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