MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Keloid

(UMLS:C0022548)

Definition:: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
UMLS ID:: C0022548
MeSH ID:: D007627

Classification 1:

Name:

Tissues
MeSH Tree Number(s):: A10.165.450.300.425

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.200.425

Classification 3:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.355.274.510

Synonym(s)

Keloid

Cheloid

Cheloid of skin

KELOID

Keloid cicatrix

Keloid of skin

Keloid scar

Keloid scar of skin

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Quercetin		12653748 17086741	CTD
2	Resveratrol		23815229	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cicatrix, Hypertrophic	39%
2	Tissue Adhesions	24.4%
3	Granuloma Annulare	18.6%
4	Nephrogenic Fibrosing Dermopathy	18%
5	Nephrogenic Systemic Fibrosis	18%
6	Retroperitoneal fibrosis	17.2%
7	Lupus Erythematosus, Cutaneous	16.2%
8	Panniculitis	16.2%
9	Systemic Scleroderma	16.2%
10	Morphea	16.2%
11	Osteogenesis Imperfecta	15.5%
12	Mixed Connective Tissue Disease	15%
13	Mucinoses	15%
14	Pigmentation Disorders	14.2%
15	Peritoneal Fibrosis	14%
16	Encapsulating Peritoneal Sclerosis	14%
17	Necrobiosis Lipoidica Diabeticorum	13.6%
18	Polydipsia	13.5%
19	Panniculitis, Lupus Erythematosus	13.1%
20	Acantholysis	12.7%
21	Ascites	12.5%
22	Cartilage Diseases	12.5%
23	Gliosis	12.5%
24	Growth Disorders	12.5%
25	Hemorrhage	12.5%
26	Hyperbilirubinemia	12.5%
27	Hyperplasia	12.5%
28	Hypomenorrhea	12.5%
29	Inflammation	12.5%
30	Intraoperative Complications	12.5%
31	Ischemia	12.5%
32	Lithiasis	12.5%
33	Malacoplakia	12.5%
34	Menstruation Disturbances	12.5%
35	Metaplasia	12.5%
36	Nerve Degeneration	12.5%
37	Ochronosis	12.5%
38	Polymenorrhea	12.5%
39	Postoperative Complications	12.5%
40	Rheumatism	12.5%
41	Sclerosis	12.5%
42	Shock	12.5%
43	Ulcer	12.5%
44	Chondromalacia	12.5%
45	Hyperammonemia	12.5%
46	Hyperamylasemia	12.5%
47	Teratogenesis	12.5%
48	Cardiac Death	12.5%
49	Hypovolemia	12.5%
50	Hyperuricemia	12.5%
51	Leukoaraiosis	12.5%
52	Dysbacteriosis	12.5%
53	Delayed Graft Function	12.5%
54	Neointima	12.5%
55	Dysbiosis	12.5%
56	Cutis Laxa	12.2%
57	Lupus Erythematosus, Systemic	12.2%
58	Overlap syndrome	12.2%
59	Infarction	11.8%
60	Postoperative Hemorrhage	11.8%
61	Shock, Hemorrhagic	11.8%
62	Systemic Inflammatory Response Syndrome	11.8%
63	Dermatomyositis	11.4%
64	Cellulitis	11.4%
65	Vascular Remodeling	11.4%
66	Lupus Erythematosus, Discoid	10.5%
67	Scleroderma, Limited	10.5%
68	Extravasation of Diagnostic and Therapeutic Materials	10.4%
69	Neoplastic Processes	10.4%
70	Necrosis	10.1%
71	Granulomatosis, Orofacial	10.1%
72	Respiratory Aspiration	10.1%
73	Chromosome Aberrations	10%
74	Dehydration	10%
75	Granuloma	10%
76	Leukocytosis	10%
77	Pleocytosis	10%
78	Dupuytren Contracture	9.9%
79	Scleromyxedema	9.8%
80	Pseudoxanthoma Elasticum	8.6%
81	Genomic Instability	8.6%
82	Chromosomal Instability	8.5%
83	Azotemia	8.2%
84	Muscle Weakness	8.1%
85	Menorrhagia	8.1%
86	Mesenteric Panniculitis	8%
87	Panniculitis, Peritoneal	8%
88	Tietze's Syndrome	8%
89	Orbital Cellulitis	8%
90	Myxoid cyst	8%
91	Myxedema	7.9%
92	Incisional hernia	7.9%
93	jaundice	7.9%
94	Sudden infant death syndrome	7.8%
95	Signs and Symptoms	7.8%
96	Pathological Conditions, Anatomical	7.8%
97	Acute Disease	7.4%
98	Acute-Phase Reaction	7.4%
99	Amenorrhea	7.4%
100	Chronic disease	7.4%
101	Critical Illness	7.4%
102	Sudden death	7.4%
103	Fat necrosis	7.4%
104	Gangrene	7.4%
105	Graft Occlusion, Vascular	7.4%
106	Granuloma, Plasma Cell	7.4%
107	Hematoma	7.4%
108	Iatrogenic Disease	7.4%
109	Multiple Organ Failure	7.4%
110	Oligomenorrhea	7.4%
111	Premenstrual syndrome	7.4%
112	Recurrence	7.4%
113	Retrograde Degeneration	7.4%
114	Serositis	7.4%
115	Subcutaneous Emphysema	7.4%
116	Surgical Wound Dehiscence	7.4%
117	Syndrome	7.4%
118	Wallerian Degeneration	7.4%
119	Pyogenic granuloma	7.4%
120	Exsanguination	7.4%
121	Disease Progression	7.4%
122	Seroma	7.4%
123	Premenstrual Tension	7.4%
124	Delayed Emergence from Anesthesia	7.4%
125	Infant Death	7.4%
126	Anastomotic Leak	7.4%
127	Intraoperative Awareness	7.4%
128	Erythema Induratum	7.3%
129	Cardiotoxicity	7.2%
130	Pain, Postoperative	7.2%
131	Postoperative Nausea and Vomiting	7.1%
132	Dysmenorrhea	6.8%
133	Failed Back Surgery Syndrome	6.8%
134	Eye Hemorrhage	6.8%
135	Osteochondritis	6.7%
136	Polymyalgia Rheumatica	6.7%
137	Hemoptysis	6.7%
138	Noonan Syndrome	6.6%
139	Ecchymosis	6.6%
140	Petechiae	6.6%
141	Purpura	6.6%
142	Pyoderma Gangrenosum	6.6%
143	Asphyxia	6.2%
144	Granuloma, Respiratory Tract	6.2%
145	Shock, Traumatic	6.2%
146	Marfan Syndrome	6%
147	Disease susceptibility	6%
148	Fetal Death	6%
149	Foreign-Body Reaction	6%
150	Gastrointestinal Hemorrhage	6%
151	Hemarthrosis	6%
152	Hemoperitoneum	6%
153	Hemothorax	6%
154	Neoplasm Invasiveness	6%
155	Neoplasm Metastasis	6%
156	Neoplasm Recurrence, Local	6%
157	Postpericardiotomy Syndrome	6%
158	Prosthesis Failure	6%
159	Pruritus	6%
160	Reperfusion Injury	6%
161	Erythema	6%
162	Injection Site Reaction	6%
163	Necrolytic Migratory Erythema	6%
164	Retrobulbar Hemorrhage	6%
165	Cutaneous Fistula	6%
166	Aseptic Necrosis of Bone	6%
167	Carcinogenesis	6%
168	Neurogenic Inflammation	6%
169	Perinatal death	6%
170	Infusion site reaction	6%
171	Corneal Endothelial Cell Loss	6%
172	Vasoplegia	6%
173	Suppuration	6%
174	Metastasis	6%
175	Sinus Arrhythmia	5.9%
176	Atrial Fibrillation	5.9%
177	Atrial Flutter	5.9%
178	Dental Pulp Necrosis	5.9%
179	Granuloma, Foreign-Body	5.9%
180	Mediastinal Emphysema	5.9%
181	Surgical Wound Infection	5.9%
182	Ventricular Fibrillation	5.9%
183	Ventricular Flutter	5.9%
184	Parasystole	5.9%
185	Paroxysmal atrial fibrillation	5.9%
186	Facies	5.9%
187	Bradycardia	5.9%
188	Embryo Loss	5.9%
189	Afferent Loop Syndrome	5.9%
190	Sex Chromosome Aberrations	5.9%
191	Short Bowel Syndrome	5.9%
192	Uterine hemorrhage	5.9%
193	No-Reflow Phenomenon	5.9%
194	Homocystinuria	5.9%
195	Rheumatoid Arthritis	5.8%
196	Epistaxis	5.8%
197	Juvenile arthritis	5.8%
198	Endotoxic shock	5.7%
199	Septic Shock	5.7%
200	Toxic Shock Syndrome	5.7%
201	Lupus Nephritis	5.6%
202	Chromosome Fragility	5.6%
203	Alopecia	5.3%
204	Androgenetic Alopecia	5.3%
205	Acne Vulgaris	5.3%
206	Contact Dermatitis	5.3%
207	Eczema	5.3%
208	Erythema Multiforme	5.3%
209	Intertrigo	5.3%
210	Neurodermatitis	5.3%
211	Rhinophyma	5.3%
212	Perioral Dermatitis	5.3%
213	Acne	5.3%
214	Jaundice, Obstructive	5.2%
215	Drowning	5.1%
216	Laryngomalacia	5.1%
217	Pectus carinatum	5%
218	Breast Diseases	5%
219	Dermatitis	5%
220	Exanthema	5%
221	Facial Dermatoses	5%
222	Fetal Growth Retardation	5%
223	Hair Diseases	5%
224	Hand Dermatoses	5%
225	keratoacanthoma	5%
226	Keratosis	5%
227	Nail Diseases	5%
228	Photosensitivity Disorders	5%
229	Prurigo	5%
230	Pyoderma	5%
231	Rosacea	5%
232	Sebaceous Gland Diseases	5%
233	Skin Diseases, Vesiculobullous	5%
234	Skin Ulcer	5%
235	Sweat Gland Diseases	5%
236	Skin Diseases, Papulosquamous	5%
237	Skin Diseases, Vascular	5%
238	Acneiform Eruptions	5%
239	Ocular Rosacea	5%
240	Subcorneal pustular dermatosis	5%
241	Erythematotelangiectatic Rosacea	5%
242	Papulopustular Rosacea	5%
243	Chronic Actinic Dermatitis	5%
244	DNA Degradation, Necrotic	5%
245	Aneuploidy	5%
246	Polyploidy	5%
247	Microsatellite Instability	5%
248	Dermatitis, Atopic	5%
249	Epidermolysis Bullosa	5%
250	Heart Block	4.9%
251	Tachycardia	4.9%
252	Tachyarrhythmia	4.9%
253	Hematuria	4.9%
254	Chromosome Breakage	4.9%
255	Brain Death	4.9%
256	Rheumatoid Nodule	4.9%
257	Shock, Cardiogenic	4.9%
258	Hematoma, Epidural, Spinal	4.9%
259	Dermatitis, Phototoxic	4.9%
260	Pityriasis Lichenoides et Varioliformis Acuta	4.9%
261	Pityriasis Lichenoides	4.9%
262	Phototoxicity	4.9%
263	Sick Sinus Syndrome	4.9%
264	Trisomy	4.9%
265	Xeroderma Pigmentosum	4.8%
266	Hirsutism	4.6%
267	Foot Ulcer	4.6%
268	Dermatitis Herpetiformis	4.4%
269	Acrodermatitis	4.4%
270	Sebaceous Gland Neoplasms	4.4%
271	Porokeratosis	4.4%
272	Gianotti-Crosti Syndrome	4.4%
273	Keratoderma, Palmoplantar	4.4%
274	Hematemesis	4.3%
275	Purpura Fulminans	4.3%
276	CREST Syndrome	4.3%
277	Giant Cell Epulis	4.3%
278	Hematoma, Subdural	4.3%
279	Hematoma, Epidural, Cranial	4.3%
280	Long QT Syndrome	4.2%
281	Felty Syndrome	4.2%
282	Bronchomalacia	4.2%
283	Tracheomalacia	4.2%
284	Micronuclei, Chromosome-Defective	4.2%
285	Asthenia	4.2%
286	Body Temperature Changes	4.2%
287	Calculi	4.2%
288	Cyanosis	4.2%
289	Edema	4.2%
290	Failure to Thrive	4.2%
291	Fatigue	4.2%
292	Feminization	4.2%
293	Fetal Distress	4.2%
294	Foot Diseases	4.2%
295	Hernia	4.2%
296	Hypertrophy	4.2%
297	Motion Sickness	4.2%
298	Nails, Malformed	4.2%
299	polyps	4.2%
300	Rupture, Spontaneous	4.2%
301	Signs and Symptoms, Digestive	4.2%
302	Signs and Symptoms, Respiratory	4.2%
303	Skin Manifestations	4.2%
304	Chills	4.2%
305	Lassitude	4.2%
306	Dermatitis, Photoallergic	4.2%
307	Enterocele	4.2%
308	Atheroma	4.2%
309	Pseudophakia	4.2%
310	Urological Manifestations	4.2%
311	Stenosis	4.2%
312	Facial asymmetry	4.2%
313	Mobility Limitation	4.2%
314	Somnolence	4.2%
315	Plaque, Amyloid	4.2%
316	Plaque, Atherosclerotic	4.2%
317	Skin Abnormalities	4.1%
318	Skin Diseases, Infectious	4.1%
319	Skin Neoplasms	4.1%
320	Lipomatosis	4%
321	Cross Infection	4%
322	Hyphema	4%
323	Retinal Neovascularization	4%
324	Septicemia	4%
325	Vitreous Hemorrhage	4%
326	Sepsis	4%
327	Abscess	3.9%
328	Empyema	3.9%
329	Femur Head Necrosis	3.9%
330	Fetal Resorption	3.9%
331	Lymphatic Metastasis	3.9%
332	Neoplasms, Unknown Primary	3.9%
333	Peptic Ulcer Hemorrhage	3.9%
334	Sudden Cardiac Death	3.9%
335	Leukemic Infiltration	3.9%
336	Premenstrual Dysphoric Disorder	3.9%
337	Choroidal Neovascularization	3.9%
338	Primary Graft Dysfunction	3.9%
339	Neoplasm Micrometastasis	3.9%
340	Dumping Syndrome	3.9%
341	Dermatitis, Irritant	3.9%
342	Acne Conglobata	3.9%
343	Sinus Arrest, Cardiac	3.9%
344	Metrorrhagia	3.9%
345	Livedo Reticularis	3.8%
346	Xeroderma	3.8%
347	Urticaria Pigmentosa	3.8%
348	Subacute Combined Degeneration	3.8%
349	Eosinophilic Granuloma	3.7%
350	Rheumatoid Vasculitis	3.7%
351	Hematoma, Subdural, Spinal	3.6%
352	Phantom pain	3.6%
353	Phantom Limb Pain	3.6%
354	Mucopolysaccharidosis III	3.6%
355	Cyst	3.5%
356	Eye Manifestations	3.5%
357	Neurologic Manifestations	3.5%
358	Leukoplakia	3.4%
359	Cardiac Output, High	3.4%
360	Myocardial Stunning	3.4%
361	Reticulocytosis	3.4%
362	Low Cardiac Output Syndrome	3.4%
363	Airway Remodeling	3.4%
364	Dermatitis, Occupational	3.4%
365	Retinal Hemorrhage	3.4%
366	Ventricular Remodeling	3.3%
367	Thrombocytopenic purpura	3.3%
368	Kernicterus	3.3%
369	Erythema Infectiosum	3.3%
370	Choroid Hemorrhage	3.3%
371	Mastocytosis	3.3%
372	Melena	3.3%
373	Intermittent Claudication	3.3%
374	Ectodermal Dysplasia	3.3%
375	Aplasia Cutis Congenita	3.3%
376	Exanthema Subitum	3.3%
377	Renal Colic	3.3%
378	Anhidrosis	3.3%
379	Cholesteatoma	3.3%
380	Pressure Ulcer	3.3%
381	Folliculitis	3.3%
382	Foot Dermatoses	3.3%
383	Gynecomastia	3.3%
384	Hypertrichosis	3.3%
385	Hypohidrosis	3.3%
386	Hypotrichosis	3.3%
387	Leg Ulcer	3.3%
388	Miliaria	3.3%
389	Parakeratosis	3.3%
390	Parapsoriasis	3.3%
391	Pityriasis	3.3%
392	Postpartum Hemorrhage	3.3%
393	Psoriasis	3.3%
394	Sweet Syndrome	3.3%
395	Hidradenitis	3.3%
396	Onycholysis	3.3%
397	Miliaria Rubra	3.3%
398	Hyperpigmentation	3.3%
399	Lichenoid Eruptions	3.3%
400	Chloracne	3.3%
401	Sicca Syndrome	3.3%
402	Sjogren's Syndrome	3.3%
403	Abdominal Pain	3.3%
404	Gingival Hemorrhage	3.3%
405	Dermatitis, Allergic Contact	3.3%
406	Erythema Nodosum	3.3%
407	Monosomy	3.3%
408	Purpura, Hyperglobulinemic	3.3%
409	Tetraploidy	3.3%
410	Stillbirth	3.3%
411	Toxic Epidermal Necrolysis	3.2%
412	Stevens-Johnson Syndrome	3.2%
413	Adams-Stokes Syndrome	3.2%
414	Atrioventricular Block	3.2%
415	Bundle-Branch Block	3.2%
416	Papillon-Lefevre Disease	3.2%
417	Atrial Premature Complexes	3.2%
418	Sinoatrial Block	3.2%
419	Tachycardia, Paroxysmal	3.2%
420	Supraventricular tachycardia	3.2%
421	Tachycardia, Ventricular	3.2%
422	Tachycardia, Reciprocating	3.2%
423	Subarachnoid Hemorrhage	3.2%
424	Cerebral Hemorrhage	3.2%
425	Diaper Rash	3.2%
426	Hematoma, Subdural, Intracranial	3.2%
427	Hematoma, Subdural, Chronic	3.2%
428	Hematoma, Subdural, Acute	3.2%
429	Viremia	3.1%
430	Parasitemia	3.1%
431	Tinea Pedis	3%
432	Tinea Capitis	3%
433	Onychomycosis	3%
434	Hyperkeratosis, Epidermolytic	2.9%
435	Ecthyma	2.9%
436	Hypergammaglobulinemia	2.8%
437	Lupus Vasculitis, Central Nervous System	2.8%
438	Romano-Ward Syndrome	2.8%
439	Eye pain	2.8%
440	Diverticulum	2.7%
441	Diverticulosis	2.7%
442	Muscular Atrophy	2.7%
443	Ichthyosis, X-Linked	2.7%
444	Sjogren-Larsson Syndrome	2.7%
445	Breast Cyst	2.7%
446	Actinic keratosis	2.7%
447	Pemphigoid, Benign Mucous Membrane	2.7%
448	Pemphigus	2.7%
449	Piedra	2.7%
450	Sunburn	2.7%
451	Argyria	2.6%
452	Lactation Disorder	2.6%
453	Mastitis	2.6%
454	Urticaria	2.6%
455	Mucopolysaccharidosis II	2.6%
456	Adiposis Dolorosa	2.6%
457	Pruritus Vulvae	2.6%
458	Mastocytoma	2.6%
459	Pruritus Ani	2.6%
460	Behcet Syndrome	2.6%
461	Granuloma, Laryngeal	2.5%
462	Bacteremia	2.5%
463	Myocardial Reperfusion Injury	2.5%
464	Cell Transformation, Viral	2.5%
465	Anorexia	2.5%
466	Anoxia	2.5%
467	Constipation	2.5%
468	Diarrhea	2.5%
469	Dyspepsia	2.5%
470	Eructation	2.5%
471	Fever	2.5%
472	Flatulence	2.5%
473	Flushing	2.5%
474	Halitosis	2.5%
475	Heartburn	2.5%
476	Diaphragmatic Hernia	2.5%
477	Hiccough	2.5%
478	Hypercalciuria	2.5%
479	Hypercapnia	2.5%
480	Hyperphagia	2.5%
481	Intestinal Polyps	2.5%
482	Nausea	2.5%
483	Pallor	2.5%
484	Psychophysiologic Disorders	2.5%
485	Splenomegaly	2.5%
486	Vomiting	2.5%
487	Hypocapnia	2.5%
488	Dyschezia	2.5%
489	Hypoxia	2.5%
490	Hyperoxia	2.5%
491	Lower Urinary Tract Symptoms	2.5%
492	Hypoxemia	2.5%
493	Urinoma	2.5%
494	Fungemia	2.5%
495	Hidradenitis Suppurativa	2.4%
496	Lichen Planus	2.4%
497	Melanosis	2.4%
498	Chloasma	2.4%
499	Pityriasis Rosea	2.4%
500	Pityriasis Rubra Pilaris	2.4%
501	Vitiligo	2.4%
502	Lichen Nitidus	2.4%
503	Purpura, Thrombotic Thrombocytopenic	2.4%
504	Tachycardia, Atrioventricular Nodal Reentry	2.4%
505	Tachycardia, Ectopic Atrial	2.4%
506	Tachycardia, Ectopic Junctional	2.4%
507	Sinus Tachycardia	2.4%
508	Torsades de Pointes	2.4%
509	Accelerated Idioventricular Rhythm	2.4%
510	Albinism	2.3%
511	Erythema Chronicum Migrans	2.3%
512	Abdomen, Acute	2.3%
513	Dermatomycoses	2.2%
514	Mucocutaneous Lymph Node Syndrome	2.2%
515	Skin Diseases, Bacterial	2.2%
516	Drug Eruptions	2.2%
517	Lipodystrophy	2.2%
518	Malignant Atrophic Papulosis	2.2%
519	Polyarteritis Nodosa	2.2%
520	Takayasu Arteritis	2.2%
521	Waterhouse-Friderichsen Syndrome	2.2%
522	Philadelphia Chromosome	2.1%
523	Respiratory Tract Fistula	2.1%
524	Body Weight	2%
525	Endotoxemia	2%
526	Acanthosis Nigricans	2%
527	Alopecia Areata	2%
528	Lentigo	2%
529	Apnea	2%
530	Cheyne-Stokes Respiration	2%
531	Decerebrate State	2%
532	Dyspnea	2%
533	Cardiomegaly	2%
534	Hemiparesis	2%
535	Hepatomegaly	2%
536	Hyperventilation	2%
537	Meningism	2%
538	Mouth Breathing	2%
539	Paresis	2%
540	Parovarian Cyst	2%
541	Seizures	2%
542	Sensation Disorders	2%
543	Sneezing	2%
544	Spermatocele	2%
545	Oral Fistula	2%
546	Complex partial seizures	2%
547	Tachypnea	2%
548	Monoparesis	2%
549	Gait Disorders, Neurologic	2%
550	Neuromuscular Manifestations	2%
551	Cardiac Hypertrophy	2%
552	Sweating, Gustatory	2%
553	Auriculotemporal Syndrome	2%
554	Edema, Cardiac	2%
555	Mental Fatigue	2%
556	Orthostatic intolerance	2%
557	Hypoventilation	2%
558	Autoimmune thrombocytopenia	2%
559	Immune thrombocytopenic purpura	2%
560	Lice Infestations	2%
561	Vaginal Fistula	2%
562	Varicose Ulcer	2%
563	Rectocele	2%
564	Breast Neoplasms, Male	2%
565	Triple Negative Breast Neoplasms	2%
566	Body Weight Changes	2%
567	Mycetoma	2%
568	Galactorrhea	1.9%
569	Nail-Patella Syndrome	1.9%
570	Porphyrias, Hepatic	1.9%
571	Sarcopenia	1.9%
572	Hoarseness	1.8%
573	Sleep Wake Disorders	1.8%
574	Pupil Disorders	1.7%
575	Neurobehavioral Manifestations	1.7%
576	Nasal Polyps	1.7%
577	Pleural Rub	1.7%
578	Rales	1.7%
579	Respiratory Sounds	1.7%
580	Rhonchi	1.7%
581	Stridor	1.7%
582	Wheezing	1.7%
583	Asterixis	1.7%
584	Ballismus	1.7%
585	Larva Migrans	1.7%
586	Leishmaniasis	1.7%
587	Molluscum Contagiosum	1.7%
588	Vertigo	1.7%
589	Lichen Planus, Oral	1.7%
590	Angioedema	1.6%
591	Pain	1.6%
592	Ache	1.6%
593	Onchocerciasis	1.6%
594	Meningocele	1.6%
595	Oliguria	1.6%
596	Polyuria	1.6%
597	Proteinuria	1.6%
598	Urinary Calculi	1.6%
599	Encephalocele	1.6%
600	Chromoblastomycosis	1.6%
601	Dermatophytosis	1.6%
602	Sporotrichosis	1.6%
603	Tinea	1.6%
604	Tinea Versicolor	1.6%
605	Trichophytosis	1.6%
606	Hyalohyphomycosis	1.6%
607	Back Pain	1.6%
608	Bulimia	1.6%
609	Neck Pain	1.6%
610	Chest Pain	1.6%
611	Colonic Polyps	1.6%
612	Dizziness	1.6%
613	Dysuria	1.6%
614	Facial Pain	1.6%
615	Fever of Unknown Origin	1.6%
616	Flank Pain	1.6%
617	Headache	1.6%
618	Nocturia	1.6%
619	Pain, Intractable	1.6%
620	Pelvic Pain	1.6%
621	Snoring	1.6%
622	Chronic pain	1.6%
623	Lightheadedness	1.6%
624	Pain, Referred	1.6%
625	Prostatism	1.6%
626	Throbbing Headache	1.6%
627	Labor Pain	1.6%
628	Cancer Pain	1.6%
629	Nociceptive Pain	1.6%
630	Gait Ataxia	1.6%
631	Acute Generalized Exanthematous Pustulosis	1.6%
632	Underweight	1.6%
633	Overweight	1.6%
634	Basal Ganglia Hemorrhage	1.6%
635	Candidemia	1.5%
636	Voice Disorders	1.5%
637	Voice Disturbance	1.5%
638	Warts	1.4%
639	Gagging	1.4%
640	Akathisia	1.4%
641	Restlessness	1.4%
642	Psychomotor Agitation	1.4%
643	Leukoplakia, Oral	1.4%
644	Vesicovaginal Fistula	1.4%
645	Candidiasis, Chronic Mucocutaneous	1.4%
646	Cutaneous Candidiasis	1.4%
647	Erysipelas	1.4%
648	Serum Sickness	1.4%
649	Staphylococcal Skin Infections	1.4%
650	Variegate Porphyria	1.4%
651	Acute intermittent porphyria	1.4%
652	Porphyria Cutanea Tarda	1.4%
653	Erythrasma	1.4%
654	Carcinoma, Lobular	1.4%
655	Arthritis, Psoriatic	1.4%
656	Leishmaniasis, Cutaneous	1.4%
657	Eczema Herpeticum	1.4%
658	Fusariosis	1.3%
659	Putaminal Hemorrhage	1.3%
660	Biliary Fistula	1.3%
661	Gastric Fistula	1.3%
662	Congenital diaphragmatic hernia	1.3%
663	Morning Sickness	1.3%
664	Gait Apraxia	1.3%
665	Anosmia	1.3%
666	Ataxia	1.3%
667	Athetosis	1.3%
668	Catalepsy	1.3%
669	Dental Fistula	1.3%
670	Dystonia	1.3%
671	Hemiplegia	1.3%
672	Locked-In Syndrome	1.3%
673	Muscle Hypertonia	1.3%
674	Muscle hypotonia	1.3%
675	Myoclonus	1.3%
676	Myotonia	1.3%
677	Neuralgia	1.3%
678	Oroantral Fistula	1.3%
679	Paraplegia	1.3%
680	Pseudobulbar Palsy	1.3%
681	Quadriplegia	1.3%
682	Spasm	1.3%
683	Spastic Paraplegia	1.3%
684	Status Epilepticus	1.3%
685	Taste Disorders	1.3%
686	Tremor	1.3%
687	Monoplegia	1.3%
688	Hypokinesia	1.3%
689	Left Ventricular Hypertrophy	1.3%
690	Gastroparesis	1.3%
691	Right Ventricular Hypertrophy	1.3%
692	Paraparesis	1.3%
693	Bradykinesia	1.3%
694	Waxy flexibility	1.3%
695	Action Tremor	1.3%
696	Resting Tremor	1.3%
697	Dysosmia	1.3%
698	Quadriparesis	1.3%
699	Olfaction Disorders	1.3%
700	Myokymia	1.3%
701	Somatosensory Disorders	1.3%
702	Neuropathic pain	1.3%
703	Hyperkinesia	1.3%
704	Intention tremor	1.3%
705	Giant Cell Arteritis	1.3%
706	Temporal Arteritis	1.3%
707	Rectal Prolapse	1.3%
708	Uterine Prolapse	1.3%
709	Vaginal Prolapse	1.3%
710	Weight Gain	1.3%
711	Jet Lag Syndrome	1.2%
712	Reflex, Abnormal	1.2%
713	Hyporeflexia	1.2%
714	Hyperreflexia	1.2%
715	Emaciation	1.2%
716	Low Back Pain	1.2%
717	Visceral Pain	1.2%
718	Birth Weight	1.2%
719	Hereditary Angioedema Type III	1.2%
720	Hereditary Angioedema Types I and II	1.2%
721	Angioedemas, Hereditary	1.2%
722	Epidermodysplasia Verruciformis	1.2%
723	Herpes Labialis	1.2%
724	Diabetic Foot	1.2%
725	Staphylococcal Scalded Skin Syndrome	1.1%
726	Vision Disorders	1.1%
727	Metamorphopsia	1.1%
728	Visual Impairment	1.1%
729	Bronchial Fistula	1.1%
730	Metatarsalgia	1.1%
731	Pancreatic Fistula	1.1%
732	Anisocoria	1.1%
733	Confusion	1.1%
734	Facial paralysis	1.1%
735	Intestinal Fistula	1.1%
736	Lethargy	1.1%
737	Memory Disorders	1.1%
738	Muscle Cramp	1.1%
739	Perceptual Disorders	1.1%
740	Psychomotor Disorders	1.1%
741	Tonic Pupil	1.1%
742	Anhedonia	1.1%
743	Disorientation	1.1%
744	Gastroschisis	1.1%
745	Enterocutaneous Fistula	1.1%
746	Fetal Hypoxia	1.1%
747	Facial Paresis	1.1%
748	Memory Loss	1.1%
749	Hemisensory Neglect	1.1%
750	Dysacusis	1.1%
751	Blastomycosis	1.1%
752	Dyspnea, Paroxysmal	1.1%
753	Mastodynia	1.1%
754	Respiratory Paralysis	1.1%
755	Salivary Gland Fistula	1.1%
756	Chorea	1.1%
757	Cystocele	1.1%
758	Tetany	1.1%
759	Urinary Incontinence	1.1%
760	Breakthrough Pain	1.1%
761	HIV-Associated Lipodystrophy Syndrome	1.1%
762	Albuminuria	1.1%
763	Hemoglobinuria	1.1%
764	Alice in Wonderland Syndrome	1.1%
765	Peutz-Jeghers Syndrome	1.1%
766	carbuncle	1%
767	Condylomata Acuminata	1%
768	Furunculosis	1%
769	furuncle	1%
770	Cachexia	1%
771	Alexia	1%
772	Impetigo	1%
773	Dyslexia	1%
774	Rhinoscleroma	1%
775	Menkes Kinky Hair Syndrome	1%
776	Umbilical hernia	1%
777	Toothache	1%
778	Hydrops Fetalis	1%
779	Hyperemesis Gravidarum	1%
780	Fetal Weight	1%
781	Dysgeusia	1%
782	Formication	1%
783	Hyperalgesia	1%
784	Hyperesthesia	1%
785	Hypesthesia	1%
786	Language Disorders	1%
787	Numbness	1%
788	Paresthesia	1%
789	Paraparesis, Spastic	1%
790	Trismus	1%
791	Epilepsia Partialis Continua	1%
792	Hypogeusia	1%
793	Brown-Sequard Syndrome	1%
794	Lockjaw	1%
795	Allodynia	1%
796	Ageusia	1%
797	Consciousness Disorders	1%
798	Mental Retardation	1%
799	Depressed Level of Consciousness	1%
800	Mental deficiency	1%
801	Intellectual Disability	1%
802	Catatonia	0.9%
803	Musculoskeletal Pain	0.9%
804	Ophthalmoplegia	0.9%
805	External Ophthalmoplegia	0.9%
806	Aphonia	0.9%
807	Arthralgia	0.9%
808	Sleep Deprivation	0.9%
809	Polyarthralgia	0.9%
810	Dysphonia	0.9%
811	Cerebrospinal Fluid Otorrhea	0.9%
812	Cerebrospinal Fluid Rhinorrhea	0.9%
813	Obesity	0.9%
814	Vocal Cord Paralysis	0.8%
815	Diplopia	0.8%
816	Muscle Rigidity	0.8%
817	Muscle Spasticity	0.8%
818	Scotoma	0.8%
819	Photophobia	0.8%
820	Cogwheel Rigidity	0.8%
821	Hemifacial Spasm	0.8%
822	Amaurosis	0.8%
823	Blindness	0.8%
824	Nuchal Rigidity	0.8%
825	Angina Pectoris	0.8%
826	Urinary Bladder Fistula	0.8%
827	Agnosia	0.8%
828	Apraxias	0.8%
829	Hallucinations	0.8%
830	Hemianopsia	0.8%
831	Hyperacusis	0.8%
832	Tinnitus	0.8%
833	Visual Agnosia	0.8%
834	Anosognosia	0.8%
835	Wernicke-Korsakoff Syndrome	0.8%
836	Phonophobia	0.8%
837	Hearing Loss	0.8%
838	Cerebellar Ataxia	0.8%
839	Torticollis	0.8%
840	Sciatica	0.8%
841	Urge Incontinence	0.8%
842	Tardive Dyskinesia	0.8%
843	Agraphia	0.8%
844	Anomia	0.8%
845	Cluttering	0.8%
846	Language Development Disorders	0.8%
847	Speech Disorders	0.8%
848	Syncope	0.8%
849	Stupor	0.8%
850	Dysgraphia	0.8%
851	Presyncope	0.8%
852	Dyslalia	0.8%
853	Dyskinesia, Drug-Induced	0.7%
854	Alcohol Withdrawal Seizures	0.7%
855	Arteriovenous fistula	0.7%
856	Aphasia	0.7%
857	Articulation Disorders	0.7%
858	Echolalia	0.7%
859	Stuttering	0.7%
860	Dysphasia	0.7%
861	Amblyopia	0.7%
862	Amnesia	0.7%
863	Delirium	0.7%
864	Horner Syndrome	0.7%
865	Dissociative Amnesia	0.7%
866	Color blindness	0.7%
867	Global Amnesia	0.7%
868	Rectal Fistula	0.7%
869	Anal Fistula	0.7%
870	Shoulder Pain	0.7%
871	Pediatric Obesity	0.7%
872	Dysarthria	0.7%
873	Amaurosis Fugax	0.7%
874	Blindness, Cortical	0.7%
875	Dyscalculia	0.7%
876	Angina, Unstable	0.7%
877	Deafness	0.7%
878	Hearing Loss, Sudden	0.7%
879	Gerstmann Syndrome	0.7%
880	Hearing Loss, Bilateral	0.7%
881	Hearing Loss, High-Frequency	0.7%
882	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
883	Prosopagnosia	0.7%
884	Apraxia, Ideomotor	0.7%
885	Persistent Vegetative State	0.7%
886	Charles Bonnet Syndrome	0.7%
887	Hearing Loss, Unilateral	0.7%
888	Complete Hearing Loss	0.7%
889	Alien Hand Syndrome	0.7%
890	Deaf Mutism	0.7%
891	Kidney Calculi	0.6%
892	Ureteral Calculi	0.6%
893	Akathisia, Drug-Induced	0.6%
894	Myalgia	0.6%
895	Mutism	0.6%
896	Selective Mutism	0.6%
897	Angina Pectoris, Variant	0.6%
898	Retrograde amnesia	0.6%
899	Amnesia, Anterograde	0.6%
900	Alexia, Pure	0.6%
901	Auditory Perceptual Disorders	0.5%
902	Amnesia, Transient Global	0.5%
903	Ophthalmoplegic Migraine	0.5%
904	Progressive supranuclear palsy	0.5%
905	Kearns-Sayre syndrome	0.3%

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