MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Onchocerciasis

(UMLS:C0029001)

Definition:: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
UMLS ID:: C0029001
MeSH ID:: D009855

Classification 1:

Name:

Parasitic Diseases
MeSH Tree Number(s):: C03.335.508.700.750.361.699|C03.858.650

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.838.775.690

Synonym(s)

Onchocerciasis

Infection by Onchocerca volvulus

Infection caused by Onchocerca volvulus

ONCHOCERCOSIS

Onchocerca; infestation

Onchocercosis

River Blindness

Robles

infestation; Onchocerca

10.

onchocerciasis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ivermectin	FAERS: 4		US FAERS
2	Albendazole		1796233	CTD
3	Diethylcarbamazine		87927 7020746 7387952	CTD
4	Ivermectin		View details 15993957 16257066 19712154 20595473 20630055 28746337 29210346	CTD OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Larva Migrans	44.5%
2	Leishmaniasis	37%
3	Lice Infestations	33.1%
4	Loiasis	29.2%
5	Leishmaniasis, Cutaneous	26.7%
6	Dirofilariasis	26.7%
7	Gnathostomiasis	22.7%
8	Ascaridida Infections	19.5%
9	Oxyurida Infections	19.5%
10	Helminthiasis, Animal	18.9%
11	Protozoan Infections	17.6%
12	Cestode Infections	17.5%
13	Trematode Infections	17.5%
14	Toxocariasis	17.3%
15	Mite Infestations	16.8%
16	Myiasis	16.8%
17	Tick Infestations	16.8%
18	Strongyle Infections, Equine	15.3%
19	Pyoderma Gangrenosum	14.9%
20	Parasitic Diseases, Animal	14.6%
21	Liver Diseases, Parasitic	14.2%
22	Protozoan Infections, Animal	14%
23	Intestinal Diseases, Parasitic	14%
24	Pregnancy Complications, Parasitic	14%
25	Fascioliasis	14%
26	Parasitemia	13.8%
27	Giardiasis	13.8%
28	Cryptosporidiosis	13.7%
29	Lupus Erythematosus, Cutaneous	13.6%
30	Panniculitis	13.6%
31	Systemic Scleroderma	13.6%
32	Morphea	13.6%
33	Hypodermyiasis	13.3%
34	Ascariasis	12.9%
35	Hookworm Infections	12.9%
36	Oxyuriasis	12.9%
37	Strongyloidiasis	12.9%
38	Trichostrongyloidiasis	12.9%
39	Breast Diseases	12.6%
40	Dermatitis	12.6%
41	Exanthema	12.6%
42	Facial Dermatoses	12.6%
43	Hair Diseases	12.6%
44	Hand Dermatoses	12.6%
45	keratoacanthoma	12.6%
46	Keratosis	12.6%
47	Nail Diseases	12.6%
48	Photosensitivity Disorders	12.6%
49	Prurigo	12.6%
50	Pyoderma	12.6%
51	Rosacea	12.6%
52	Sebaceous Gland Diseases	12.6%
53	Skin Diseases, Vesiculobullous	12.6%
54	Skin Ulcer	12.6%
55	Sweat Gland Diseases	12.6%
56	Skin Diseases, Papulosquamous	12.6%
57	Skin Diseases, Vascular	12.6%
58	Acneiform Eruptions	12.6%
59	Ocular Rosacea	12.6%
60	Subcorneal pustular dermatosis	12.6%
61	Erythematotelangiectatic Rosacea	12.6%
62	Papulopustular Rosacea	12.6%
63	Chronic Actinic Dermatitis	12.6%
64	Opportunistic Infections	12.1%
65	Acne Vulgaris	11.9%
66	Contact Dermatitis	11.9%
67	Eczema	11.9%
68	Erythema Multiforme	11.9%
69	Intertrigo	11.9%
70	Neurodermatitis	11.9%
71	Rhinophyma	11.9%
72	Perioral Dermatitis	11.9%
73	Acne	11.9%
74	Dermatomycoses	11.7%
75	Skin Diseases, Bacterial	11.7%
76	Babesiosis	11.7%
77	Echinococcosis, Hepatic	11.7%
78	Dermatitis, Atopic	11.2%
79	Epidermolysis Bullosa	11.2%
80	Erythema Infectiosum	11%
81	Xeroderma Pigmentosum	11%
82	Exanthema Subitum	10.9%
83	Diphyllobothriasis	10.6%
84	Echinococcosis	10.6%
85	Hymenolepiasis	10.6%
86	Opisthorchiasis	10.6%
87	Schistosomiasis	10.6%
88	Foot Diseases	10.5%
89	Helminthiasis	10.5%
90	Amebiasis	10.3%
91	Coccidiosis	10.3%
92	Malaria	10.3%
93	Acanthamoeba Infection	10.3%
94	Trichomonas Infections	10.3%
95	Ciliophora Infections	10.3%
96	Balamuthia Infection	10.3%
97	Erythema Induratum	10.3%
98	Skin Abnormalities	10.2%
99	Skin Neoplasms	10.2%
100	Pigmentation Disorders	10.2%
101	Lipomatosis	10.1%
102	Pruritus	10.1%
103	Erythema	10.1%
104	Necrolytic Migratory Erythema	10.1%
105	Cutaneous Fistula	10.1%
106	Nephrogenic Fibrosing Dermopathy	10.1%
107	Nephrogenic Systemic Fibrosis	10.1%
108	Dermatitis Herpetiformis	10.1%
109	Acrodermatitis	10%
110	Sebaceous Gland Neoplasms	10%
111	Porokeratosis	10%
112	Gianotti-Crosti Syndrome	10%
113	Keratoderma, Palmoplantar	10%
114	Foot Ulcer	9.9%
115	Acanthamoeba Keratitis	9.8%
116	Dermatitis, Phototoxic	9.8%
117	Pityriasis Lichenoides et Varioliformis Acuta	9.8%
118	Pityriasis Lichenoides	9.8%
119	Phototoxicity	9.8%
120	Enterobiasis	9.6%
121	Dermatomyositis	9.6%
122	Necrobiosis Lipoidica Diabeticorum	9.4%
123	Ecthyma	9.4%
124	Panniculitis, Lupus Erythematosus	9.4%
125	Mycetoma	9.1%
126	Tinea Capitis	9.1%
127	Onychomycosis	9.1%
128	Malaria, Cerebral	9.1%
129	Xeroderma	8.6%
130	Liver Abscess, Amebic	8.5%
131	Dermatitis, Photoallergic	8.4%
132	Mastocytosis	8.3%
133	Hidradenitis Suppurativa	8.2%
134	Urticaria Pigmentosa	8.2%
135	Neurocysticercosis	8.2%
136	Trichinellosis	8%
137	Lupus Erythematosus, Discoid	8%
138	Scleroderma, Limited	8%
139	Dermatitis, Irritant	7.9%
140	Acne Conglobata	7.9%
141	Connective Tissue Diseases	7.8%
142	Cutis Laxa	7.8%
143	Molluscum Contagiosum	7.8%
144	Pseudoxanthoma Elasticum	7.7%
145	Chromoblastomycosis	7.7%
146	Dermatophytosis	7.7%
147	Sporotrichosis	7.7%
148	Tinea	7.7%
149	Tinea Versicolor	7.7%
150	Trichophytosis	7.7%
151	Hyalohyphomycosis	7.7%
152	Erythema Chronicum Migrans	7.5%
153	Ectodermal Dysplasia	7.5%
154	Aplasia Cutis Congenita	7.5%
155	Anhidrosis	7.5%
156	Cholesteatoma	7.5%
157	Pressure Ulcer	7.5%
158	Folliculitis	7.5%
159	Foot Dermatoses	7.5%
160	Gynecomastia	7.5%
161	Hypertrichosis	7.5%
162	Hypohidrosis	7.5%
163	Hypotrichosis	7.5%
164	Leg Ulcer	7.5%
165	Miliaria	7.5%
166	Parakeratosis	7.5%
167	Parapsoriasis	7.5%
168	Pityriasis	7.5%
169	Psoriasis	7.5%
170	Sweet Syndrome	7.5%
171	Hidradenitis	7.5%
172	Onycholysis	7.5%
173	Miliaria Rubra	7.5%
174	Hyperpigmentation	7.5%
175	Lichenoid Eruptions	7.5%
176	Chloracne	7.5%
177	Cysticercosis	7.2%
178	Schistosomiasis japonica	7.2%
179	Schistosomiasis mansoni	7.2%
180	Sparganosis	7.2%
181	Erythema Nodosum	7%
182	Superinfection	6.9%
183	Entamoebiasis	6.8%
184	Malaria, Falciparum	6.8%
185	Malaria, Vivax	6.8%
186	Toxoplasmosis	6.8%
187	Trypanosomiasis	6.8%
188	Isosporiasis	6.8%
189	Dermatitis, Occupational	6.8%
190	Warts	6.7%
191	Nematode infections	6.7%
192	Tinea Pedis	6.7%
193	Candidiasis, Chronic Mucocutaneous	6.6%
194	Cutaneous Candidiasis	6.6%
195	Dermatitis, Allergic Contact	6.6%
196	Erysipelas	6.5%
197	Staphylococcal Skin Infections	6.5%
198	Erythrasma	6.5%
199	Papillon-Lefevre Disease	6.5%
200	Toxic Epidermal Necrolysis	6.5%
201	Stevens-Johnson Syndrome	6.5%
202	Granuloma Annulare	6.1%
203	Acantholysis	6.1%
204	Breast Cyst	6.1%
205	Actinic keratosis	6.1%
206	Pemphigoid, Benign Mucous Membrane	6.1%
207	Pemphigus	6.1%
208	Piedra	6.1%
209	Sunburn	6.1%
210	Argyria	6%
211	Hirsutism	6%
212	Lactation Disorder	6%
213	Mastitis	6%
214	Urticaria	6%
215	Adiposis Dolorosa	5.9%
216	Pruritus Vulvae	5.9%
217	Mastocytoma	5.9%
218	Pruritus Ani	5.9%
219	Diaper Rash	5.9%
220	Ichthyosis, X-Linked	5.7%
221	Eczema Herpeticum	5.7%
222	Sjogren-Larsson Syndrome	5.7%
223	Fusariosis	5.7%
224	Behcet Syndrome	5.5%
225	Trichomonas Vaginitis	5.4%
226	Hyperkeratosis, Epidermolytic	5.4%
227	AIDS-Related Opportunistic Infections	5.1%
228	Blackwater Fever	5.1%
229	Leishmaniasis, Visceral	5.1%
230	African Trypanosomiasis	5.1%
231	Chagas Disease	5.1%
232	Blastomycosis	5.1%
233	Mucocutaneous Lymph Node Syndrome	5%
234	Drug Eruptions	5%
235	Lipodystrophy	5%
236	Livedo Reticularis	5%
237	Malignant Atrophic Papulosis	5%
238	Albinism	5%
239	Secernentea Infections	5%
240	Lichen Planus	4.9%
241	Melanosis	4.9%
242	Chloasma	4.9%
243	Pityriasis Rosea	4.9%
244	Pityriasis Rubra Pilaris	4.9%
245	Vitiligo	4.9%
246	Lichen Nitidus	4.9%
247	Polyarteritis Nodosa	4.9%
248	Takayasu Arteritis	4.9%
249	Epidermodysplasia Verruciformis	4.9%
250	Herpes Labialis	4.9%
251	Staphylococcal Scalded Skin Syndrome	4.9%
252	Toxoplasmosis, Cerebral	4.7%
253	Rhinoscleroma	4.7%
254	Onchocerciasis	4.7%
255	Nail-Patella Syndrome	4.4%
256	Condylomata Acuminata	4.3%
257	Porphyrias, Hepatic	4.3%
258	Furunculosis	4.3%
259	furuncle	4.3%
260	Impetigo	4.2%
261	Collagen Diseases	4.2%
262	Mixed Connective Tissue Disease	4.2%
263	Mucinoses	4.2%
264	carbuncle	4%
265	Alopecia	4%
266	Sweating, Gustatory	4%
267	Androgenetic Alopecia	4%
268	Auriculotemporal Syndrome	4%
269	Varicose Ulcer	4%
270	Breast Neoplasms, Male	4%
271	Triple Negative Breast Neoplasms	4%
272	Galactorrhea	3.9%
273	Acanthosis Nigricans	3.7%
274	Alopecia Areata	3.7%
275	Filariasis	3.7%
276	Lentigo	3.7%
277	Cartilage Diseases	3.5%
278	Rheumatism	3.5%
279	Chondromalacia	3.5%
280	Chagas Cardiomyopathy	3.4%
281	Toxoplasmosis, Congenital	3.4%
282	Lupus Erythematosus, Systemic	3.4%
283	Overlap syndrome	3.4%
284	Angioedema	3.3%
285	Acute Generalized Exanthematous Pustulosis	3.3%
286	Lichen Planus, Oral	3%
287	Giant Cell Arteritis	2.9%
288	Temporal Arteritis	2.9%
289	CREST Syndrome	2.9%
290	Serum Sickness	2.8%
291	Variegate Porphyria	2.8%
292	Acute intermittent porphyria	2.8%
293	Porphyria Cutanea Tarda	2.8%
294	Carcinoma, Lobular	2.8%
295	Arthritis, Psoriatic	2.8%
296	Dupuytren Contracture	2.8%
297	Scleromyxedema	2.5%
298	Cellulitis	2.4%
299	Menkes Kinky Hair Syndrome	2.2%
300	HIV-Associated Lipodystrophy Syndrome	2.2%
301	Angioedemas, Hereditary	2.1%
302	Diabetic Foot	2.1%
303	Hereditary Angioedema Type III	2%
304	Hereditary Angioedema Types I and II	2%
305	Mesenteric Panniculitis	2%
306	Panniculitis, Peritoneal	2%
307	Tietze's Syndrome	2%
308	Orbital Cellulitis	2%
309	Myxoid cyst	2%
310	Myxedema	2%
311	Noonan Syndrome	1.8%
312	Peutz-Jeghers Syndrome	1.8%
313	Osteochondritis	1.7%
314	Polymyalgia Rheumatica	1.7%
315	Marfan Syndrome	1.7%
316	Osteogenesis Imperfecta	1.7%
317	Keloid	1.6%
318	Homocystinuria	1.6%
319	Rheumatoid Arthritis	1.5%
320	Juvenile arthritis	1.5%
321	Lupus Nephritis	1.4%
322	Laryngomalacia	1.3%
323	Pectus carinatum	1.3%
324	Rheumatoid Nodule	1.1%
325	Felty Syndrome	0.9%
326	Bronchomalacia	0.9%
327	Tracheomalacia	0.9%
328	Rheumatoid Vasculitis	0.8%
329	Mucopolysaccharidosis III	0.8%
330	Sicca Syndrome	0.7%
331	Sjogren's Syndrome	0.7%
332	Lupus Vasculitis, Central Nervous System	0.7%
333	Mucopolysaccharidosis II	0.6%

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