MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Essential Hypertension

(UMLS:C0085580)

Definition:: Hypertension that occurs without known cause, or preexisting renal disease. Associated polymorphisms for a number of genes have been identified, including AGT, GNB3, and ECE1. OMIM: 145500
UMLS ID:: C0085580
MeSH ID:: D000075222

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.489.165

Synonym(s)

Essential Hypertension

Essential (primary) hypertension

Essential hypertension

Essential hypertension, NOS

HYPERTENSION ESSENTIAL

HYPERTENSION, ARTERIAL, IDIOPATHIC

HYPERTENSION, ESSENTIAL

Hypertension;essential

Idiopathic hypertension

10.

Primary Hypertension

11.

Primary hypertension

12.

Primary hypertension, NOS

13.

Systemic primary arterial hypertension

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 77		US FAERS
2	rofecoxib	FAERS: 66		OFFSIDES US FAERS
3	Finasteride	FAERS: 29		US FAERS
4	carfilzomib	FAERS: 22		US FAERS
5	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 20		US FAERS
6	NuvaRing	FAERS: 11		OFFSIDES US FAERS
7	Ibuprofen	FAERS: 9		OFFSIDES US FAERS
8	Fingolimod Hydrochloride	FAERS: 8		US FAERS
9	Isotretinoin	FAERS: 8		US FAERS
10	Sitagliptin Phosphate	FAERS: 8		US FAERS
11	4-hydroxybutyric acid	FAERS: 5		US FAERS
12	Lisinopril	FAERS: 4		OFFSIDES US FAERS
13	Rosiglitazone	FAERS: 4		US FAERS
14	Testosterone	FAERS: 4		US FAERS
15	Atorvastatin	FAERS: 3		US FAERS
16	Celecoxib	FAERS: 3		US FAERS
17	Clozapine	FAERS: 3		US FAERS
18	Sertraline	FAERS: 3		US FAERS
19	Sunitinib	FAERS: 3		US FAERS
20	ponatinib	FAERS: 3		US FAERS
21	tofacitinib	FAERS: 3		US FAERS
22	Arthrotec	FAERS: 2		US FAERS
23	Axitinib	FAERS: 2		US FAERS
24	Cyclosporine	FAERS: 2		US FAERS
25	Dasatinib	FAERS: 2		US FAERS
26	Leuprolide	FAERS: 2		US FAERS
27	Omeprazole	FAERS: 2		US FAERS
28	Ondansetron	FAERS: 2		US FAERS
29	Pregabalin	FAERS: 2		US FAERS
30	Quetiapine Fumarate	FAERS: 2		OFFSIDES US FAERS
31	Risedronic Acid	FAERS: 2		US FAERS
32	Rosuvastatin Calcium	FAERS: 2		US FAERS
33	Sildenafil Citrate	FAERS: 2		OFFSIDES US FAERS
34	Teriparatide	FAERS: 2		US FAERS
35	Thyroxine	FAERS: 2		US FAERS
36	4-Aminopyridine	FAERS: 1		US FAERS
37	Amlodipine	FAERS: 1		US FAERS
38	Bupropion	FAERS: 1		US FAERS
39	Captopril	FAERS: 1		US FAERS
40	Carbamazepine	FAERS: 1		OFFSIDES US FAERS
41	Cephalexin	FAERS: 1		US FAERS
42	Clofazimine	FAERS: 1		US FAERS
43	Crizotinib	FAERS: 1		US FAERS
44	Diclofenac	FAERS: 1		US FAERS
45	Digoxin	FAERS: 1		US FAERS
46	Duloxetine Hydrochloride	FAERS: 1		SIDER US FAERS
47	Glatiramer Acetate	FAERS: 1		US FAERS
48	Ibandronic Acid	FAERS: 1		US FAERS
49	Insulin Glargine	FAERS: 1		US FAERS
50	Irinotecan	FAERS: 1		US FAERS
51	Levofloxacin	FAERS: 1		US FAERS
52	Liraglutide	FAERS: 1		US FAERS
53	Metformin	FAERS: 1		US FAERS
54	Metoprolol	FAERS: 1		US FAERS
55	Mycophenolic Acid	FAERS: 1		US FAERS
56	Naproxen	FAERS: 1		US FAERS
57	Odefsey	FAERS: 1		US FAERS
58	Olanzapine	FAERS: 1		US FAERS
59	Ortho Evra	FAERS: 1		US FAERS
60	Paliperidone Palmitate	FAERS: 1		US FAERS
61	Paroxetine	FAERS: 1		US FAERS
62	Ranolazine	FAERS: 1		US FAERS
63	Ritonavir	FAERS: 1		US FAERS
64	Rosuvastatin Calcium	FAERS: 1		US FAERS
65	Solifenacin Succinate	FAERS: 1		US FAERS
66	Tadenan	FAERS: 1		US FAERS
67	Thyroxine	FAERS: 1		US FAERS
68	Ticagrelor	FAERS: 1		US FAERS
69	Tolterodine Tartrate	FAERS: 1		US FAERS
70	Tribenzor	FAERS: 1		US FAERS
71	Valproic Acid	FAERS: 1		US FAERS
72	Zoledronic Acid	FAERS: 1		OFFSIDES US FAERS
73	aliskiren	FAERS: 1		US FAERS
74	ambrisentan	FAERS: 1		US FAERS
75	carbidopa, levodopa drug combination	FAERS: 1		US FAERS
76	dofetilide	FAERS: 1		US FAERS
77	eltrombopag	FAERS: 1		US FAERS
78	indacaterol	FAERS: 1		US FAERS
79	palbociclib	FAERS: 1		US FAERS
80	suvorexant	FAERS: 1		US FAERS
81	valdecoxib	FAERS: 1		US FAERS
82	Allopurinol			OFFSIDES
83	Amisulpride			OFFSIDES
84	Amlodipine		25031906	CTD
85	Ampicillin			OFFSIDES
86	Atorvastatin			OFFSIDES
87	Beclomethasone		8567040	CTD
88	Benztropine			OFFSIDES
89	Bisacodyl			OFFSIDES
90	Carnitine			OFFSIDES
91	Chlorhexidine			OFFSIDES
92	Cimetidine			OFFSIDES
93	Cinacalcet			OFFSIDES
94	Clindamycin			OFFSIDES
95	Clonidine			OFFSIDES
96	Clotrimazole			OFFSIDES
97	Desonide			OFFSIDES
98	Diazepam			OFFSIDES
99	Dicyclomine			OFFSIDES
100	Diflunisal			OFFSIDES
101	Diltiazem			OFFSIDES
102	Dioctyl Sulfosuccinic Acid			OFFSIDES
103	Diphenoxylate			OFFSIDES
104	Docetaxel			OFFSIDES
105	Doxazosin			SIDER
106	Doxepin			OFFSIDES
107	Doxorubicin			OFFSIDES
108	Doxycycline			SIDER
109	Estradiol			OFFSIDES
110	Etodolac			OFFSIDES
111	Fluocinolone Acetonide			OFFSIDES
112	Flutamide			OFFSIDES
113	Fluticasone			OFFSIDES
114	Fosinopril			OFFSIDES
115	Fulvestrant			OFFSIDES
116	Gatifloxacin			OFFSIDES
117	Glipizide			OFFSIDES
118	Hydralazine			OFFSIDES
119	Hydrocortisone		8567040	CTD
120	Imipramine			OFFSIDES
121	Irbesartan			OFFSIDES SIDER
122	Losartan			SIDER
123	Lubiprostone			OFFSIDES
124	Meloxicam			OFFSIDES
125	Memantine			OFFSIDES
126	Metformin			OFFSIDES
127	Methocarbamol			OFFSIDES
128	Methylphenidate			OFFSIDES
129	Misoprostol			OFFSIDES
130	Nateglinide			OFFSIDES
131	Niacin			OFFSIDES
132	Nystatin			OFFSIDES
133	Octreotide			OFFSIDES
134	Ofloxacin			OFFSIDES
135	Oxaprozin			OFFSIDES
136	Paliperidone Palmitate			OFFSIDES
137	Pamidronate			OFFSIDES
138	Penicillin V			OFFSIDES
139	Phenazopyridine			OFFSIDES
140	Phenobarbital			OFFSIDES
141	Phentermine			OFFSIDES
142	Pindolol		2657348	CTD
143	Pramipexole			OFFSIDES
144	Progesterone			OFFSIDES
145	Quinidine			OFFSIDES
146	Risperidone			OFFSIDES
147	Selenium			OFFSIDES
148	Sulindac			OFFSIDES
149	Tamoxifen			OFFSIDES
150	Tenofovir			OFFSIDES
151	Terbinafine			OFFSIDES
152	Tiagabine			OFFSIDES
153	Tramadol			SIDER
154	Tretinoin			OFFSIDES
155	Triamcinolone			OFFSIDES
156	Vitamin B 12			OFFSIDES
157	bicalutamide			OFFSIDES
158	carbidopa, levodopa drug combination			OFFSIDES
159	cefuroxime axetil			OFFSIDES
160	chlorhexidine gluconate			OFFSIDES
161	cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester		30502333	CTD
162	desloratadine			OFFSIDES
163	exemestane			OFFSIDES
164	fexofenadine			OFFSIDES
165	hydrocodone tartrate, ibuprofen drug combination			OFFSIDES
166	magnesium citrate			OFFSIDES
167	prednisolone acetate			OFFSIDES
168	tegaserod			OFFSIDES
169	tegaserod			OFFSIDES
170	trandolapril			OFFSIDES
171	urapidil			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Malignant Hypertension	46.7%
2	White Coat Hypertension	46.7%
3	Hypertensive Retinopathy	31.8%
4	Aneurysm	31%
5	Angiomatosis	31%
6	Aortic Diseases	31%
7	Arterial Occlusive Diseases	31%
8	Hyperemia	31%
9	Hypotension	31%
10	Superior Vena Cava Syndrome	31%
11	Telangiectasis	31%
12	Vasculitis	31%
13	Venous Insufficiency	31%
14	Peripheral Vascular Diseases	31%
15	Embolism and Thrombosis	31%
16	Angiodysplasia	31%
17	Capillary Leak Syndrome	31%
18	Prehypertension	31%
19	Myocardial Ischemia	27.9%
20	Aortic Aneurysm	26.7%
21	Aortitis	26.7%
22	Leriche Syndrome	26.7%
23	Periphlebitis	26.7%
24	Phlebitis	26.7%
25	Thromboangiitis Obliterans	26.7%
26	Renal hypertension	23.1%
27	Postphlebitic Syndrome	23.1%
28	Vascular System Injuries	22%
29	Retinal Vein Occlusion	21.7%
30	Compartment syndromes	20.9%
31	Hepatic Veno-Occlusive Disease	20.9%
32	Peliosis Hepatis	20.9%
33	Varicocele	20.9%
34	Thrombophlebitis	20.6%
35	Cerebrovascular Disorders	20.5%
36	Diabetic Angiopathies	20.5%
37	Reperfusion Injury	20.5%
38	Splenic Infarction	20.5%
39	Cerebrovascular Insufficiency	20.5%
40	Vascular Neoplasms	20.5%
41	Spinal Cord Vascular Diseases	20.5%
42	Vasoplegia	20.5%
43	Blue Toe Syndrome	20.4%
44	Hemorrhoids	20.2%
45	Thoracic Outlet Syndrome	20.2%
46	Aneurysm, Dissecting	20%
47	Arteriosclerosis	20%
48	Arteritis	20%
49	Embolism	20%
50	Erythromelalgia	20%
51	Fibromuscular Dysplasia	20%
52	Raynaud Disease	20%
53	Thromboembolism	20%
54	Thrombosis	20%
55	Aneurysm, Ruptured	20%
56	Iliac Aneurysm	20%
57	Malignant Atrophic Papulosis	20%
58	Pulmonary artery stenosis	20%
59	Systemic Vasculitis	20%
60	Embolus	20%
61	Shwartzman Phenomenon	19.8%
62	Coronary Aneurysm	19.7%
63	Aortic Aneurysm, Abdominal	19.6%
64	Aortic Aneurysm, Thoracic	19.6%
65	Heart Diseases	18.5%
66	Aortic Rupture	17.9%
67	Coronary heart disease	17.8%
68	Myocardial Infarction	17.8%
69	Acute Coronary Syndrome	17.8%
70	Myocardial Reperfusion Injury	17.7%
71	Intracranial Embolism and Thrombosis	17.2%
72	Carotid Stenosis	17.1%
73	Intracranial Aneurysm	17.1%
74	Coronary Thrombosis	17.1%
75	Coronary Artery Disease	17.1%
76	Hypertension, Renovascular	17%
77	Carotid Artery Thrombosis	16.5%
78	Hand-Arm Vibration Syndrome	16.1%
79	Optic Neuropathy, Ischemic	15.5%
80	Anterior Ischemic Optic Neuropathy	15.5%
81	Mesenteric vascular insufficiency	15.5%
82	Moyamoya Disease	15.3%
83	Angioedema	15%
84	Colitis, Ischemic	14.9%
85	Arteriosclerosis Obliterans	14.8%
86	Atherosclerosis	14.8%
87	Air Embolism	14.8%
88	Endarteritis	14.8%
89	Polyarteritis Nodosa	14.8%
90	Takayasu Arteritis	14.8%
91	Venous Thrombosis	14.8%
92	Deep Vein Thrombosis	14.8%
93	Venous Thromboembolism	14.8%
94	Intracranial Arteriosclerosis	14.6%
95	Cerebral Atherosclerosis	14.6%
96	Cerebral Arteriosclerosis	14.6%
97	Arteriovenous fistula	14%
98	Retinal Artery Occlusion	13.6%
99	Retinal Vasculitis	13.6%
100	Kounis Syndrome	13.6%
101	Vasculitis, Central Nervous System	13.4%
102	Anterior Compartment Syndrome	13.3%
103	Vasculitis, Leukocytoclastic, Cutaneous	13.3%
104	Gastric Antral Vascular Ectasia	13.3%
105	Abdominal Compartment Syndrome	13.3%
106	Cerebral Thrombosis	13.3%
107	Intracranial Embolism	13.3%
108	Intracranial Thrombosis	13.3%
109	May-Thurner Syndrome	13.2%
110	Carotid Artery Diseases	13.2%
111	Brain Ischemia	13.2%
112	Hypotension, Orthostatic	13.2%
113	Cerebrovascular accident	13.2%
114	Varicose Ulcer	13.2%
115	Vasospasm, Intracranial	13.2%
116	Spinal Cord Ischemia	13.2%
117	Intracranial Arterial Diseases	13.2%
118	Primary Graft Dysfunction	13.2%
119	Post-Exercise Hypotension	13.2%
120	Angina Pectoris	13.2%
121	Coronary Occlusion	13%
122	Microvascular Angina	13%
123	Coronary Stenosis	13%
124	ST segment elevation myocardial infarction	13%
125	Embolism, Amniotic Fluid	12.6%
126	Pregnancy Complications, Cardiovascular	12.2%
127	Cardiovascular Abnormalities	12.2%
128	Brain Infarction	11.6%
129	Sinus Thrombosis, Intracranial	11.4%
130	Giant Cell Arteritis	11%
131	Temporal Arteritis	11%
132	Coronary Restenosis	10.8%
133	Scimitar Syndrome	10.7%
134	Cavernous Sinus Thrombosis	10.5%
135	Sagittal Sinus Thrombosis	10.5%
136	Cardiac Tamponade	10.3%
137	Endocarditis	10.3%
138	Cardiac Arrest	10.3%
139	Heart failure	10.3%
140	Pericardial effusion	10.3%
141	Pericarditis	10.3%
142	Pneumopericardium	10.3%
143	Cor pulmonale	10.3%
144	Ventricular Outflow Obstruction	10.3%
145	Ventricular Dysfunction	10.3%
146	Cardiomyopathies	10.3%
147	Pleuropericarditis	10.3%
148	Lemierre Syndrome	10.2%
149	Mesenteric Vascular Occlusion	10.2%
150	Mucocutaneous Lymph Node Syndrome	10.2%
151	Intermittent Claudication	10.1%
152	Pulmonary Embolism	10.1%
153	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	10.1%
154	Diabetic Retinopathy	10.1%
155	Sturge-Weber Syndrome	10.1%
156	Livedo Reticularis	10%
157	Renal Artery Obstruction	9.9%
158	Renal Artery Stenosis	9.9%
159	No-Reflow Phenomenon	9.9%
160	Hemangioma, Cavernous	9.8%
161	Shock, Cardiogenic	9.8%
162	Basal Ganglia Cerebrovascular Disease	9.8%
163	Vertebral Artery Dissection	9.8%
164	Vascular Headaches	9.8%
165	Scurvy	9.8%
166	CREST Syndrome	9.7%
167	Cerebral Arterial Diseases	9.7%
168	Vertebrobasilar Insufficiency	9.7%
169	Anterior Spinal Artery Syndrome	9.7%
170	Basilar Artery Stenosis	9.7%
171	Vertebral Artery Stenosis	9.7%
172	Intracranial Hemorrhage, Hypertensive	9.7%
173	Transient Cerebral Ischemia	9.7%
174	Angina, Unstable	9.7%
175	Subarachnoid Hemorrhage, Traumatic	9.6%
176	Carotid Artery, Internal, Dissection	9.6%
177	Cerebral Infarction	9.6%
178	Brain Stem Infarctions	9.6%
179	Infarction, Middle Cerebral Artery	9.5%
180	Infarction, Anterior Cerebral Artery	9.5%
181	Infarction, Posterior Cerebral Artery	9.5%
182	Aortic Valve Stenosis	8.9%
183	Cardiomyopathy, Dilated	8.9%
184	Pulmonary Valve Stenosis	8.9%
185	Lateral Medullary Syndrome	8.6%
186	Hepatic Vein Thrombosis	8.4%
187	Budd-Chiari Syndrome	8.4%
188	Carotid Artery Injuries	8.4%
189	Pulmonary Infarction	8.2%
190	Subclavian Steal Syndrome	8%
191	Angina Pectoris, Variant	8%
192	Ischemic contracture	8%
193	Angioedemas, Hereditary	7.9%
194	Tricuspid Atresia	7.9%
195	Arrhythmogenic Right Ventricular Dysplasia	7.9%
196	Cryoglobulinemia	7.9%
197	Leukomalacia, Periventricular	7.9%
198	Diabetic Foot	7.8%
199	Basal Ganglia Hemorrhage	7.5%
200	Subarachnoid Hemorrhage	7.3%
201	Hypoxia-Ischemia, Brain	7.3%
202	Cerebral Hemorrhage	7.3%
203	Hereditary Angioedema Type III	7.2%
204	Hereditary Angioedema Types I and II	7.2%
205	Hypertrophic Cardiomyopathy	7.1%
206	Hypertrophic obstructive cardiomyopathy	7.1%
207	Cardiac Output, High	7%
208	Myocardial Stunning	7%
209	Low Cardiac Output Syndrome	7%
210	Bacterial Endocarditis	6.8%
211	Cardiomegaly	6.8%
212	Postpericardiotomy Syndrome	6.8%
213	Cardiac Hypertrophy	6.8%
214	Rheumatic Heart Disease	6.7%
215	Aortic Valve Insufficiency	6.7%
216	Restrictive cardiomyopathy	6.7%
217	Endocardial Fibroelastosis	6.7%
218	Heart Block	6.7%
219	Heart Rupture, Post-Infarction	6.7%
220	Mitral Valve Insufficiency	6.7%
221	Mitral Valve Stenosis	6.7%
222	Myocarditis	6.7%
223	Pericarditis, Constrictive	6.7%
224	Pulmonary Valve Insufficiency	6.7%
225	Tachycardia	6.7%
226	Tricuspid Valve Insufficiency	6.7%
227	Tricuspid Valve Stenosis	6.7%
228	Tachyarrhythmia	6.7%
229	Ventricular Dysfunction, Left	6.7%
230	Right Ventricular Dysfunction	6.7%
231	Endomyocardial Fibrosis	6.7%
232	Carditis	6.7%
233	Heart Failure, Systolic	6.7%
234	Heart Failure, Diastolic	6.7%
235	Aortic coarctation	6.6%
236	Cor Triatriatum	6.6%
237	Coronary Vessel Anomalies	6.6%
238	Patent ductus arteriosus	6.6%
239	Ebstein Anomaly	6.6%
240	Heart Septal Defects	6.6%
241	Tetralogy of Fallot	6.6%
242	Transposition of Great Vessels	6.6%
243	Hypoplastic Left Heart Syndrome	6.6%
244	Shy-Drager Syndrome	6.5%
245	Supravalvular aortic stenosis	6.5%
246	Lown-Ganong-Levine Syndrome	6.5%
247	Purpura, Hyperglobulinemic	6.5%
248	Putaminal Hemorrhage	6.5%
249	Granulomatosis with polyangiitis	6.2%
250	Dementia, Vascular	6.1%
251	Cerebral Amyloid Angiopathy	6%
252	Pituitary Apoplexy	5.9%
253	Behcet Syndrome	5.7%
254	Waldenstrom Macroglobulinemia	5.7%
255	Multiple Myeloma	5.7%
256	Dextrocardia	5.3%
257	Long QT Syndrome	5.3%
258	Ataxia Telangiectasia	5.1%
259	Pseudoxanthoma Elasticum	5%
260	Aortic Valve Prolapse	4.9%
261	Tricuspid Valve Prolapse	4.9%
262	Rheumatoid Vasculitis	4.9%
263	Takotsubo Cardiomyopathy	4.9%
264	Adams-Stokes Syndrome	4.9%
265	Atrioventricular Block	4.9%
266	Bundle-Branch Block	4.9%
267	Atrial Premature Complexes	4.9%
268	Sinoatrial Block	4.9%
269	Tachycardia, Paroxysmal	4.9%
270	Supraventricular tachycardia	4.9%
271	Tachycardia, Ventricular	4.9%
272	Wolff-Parkinson-White Syndrome	4.9%
273	Tachycardia, Reciprocating	4.9%
274	Lupus Vasculitis, Central Nervous System	4.9%
275	Sick Sinus Syndrome	4.9%
276	Aortopulmonary Septal Defect	4.9%
277	Double Outlet Right Ventricle	4.9%
278	Endocardial Cushion Defects	4.9%
279	Myocardial bridging	4.9%
280	Aorticopulmonary Septal Defect	4.9%
281	Sinus Arrhythmia	4.4%
282	Atrial Fibrillation	4.4%
283	Atrial Flutter	4.4%
284	Edema, Cardiac	4.4%
285	Ventricular Fibrillation	4.4%
286	Ventricular Flutter	4.4%
287	Parasystole	4.4%
288	Paroxysmal atrial fibrillation	4.4%
289	Bradycardia	4.4%
290	Diabetic Cardiomyopathies	4.4%
291	Cardiomyopathy, Alcoholic	4.4%
292	Ectopia Cordis	4.4%
293	Sudden Cardiac Death	4.4%
294	Left Ventricular Hypertrophy	4.4%
295	Right Ventricular Hypertrophy	4.4%
296	Single umbilical artery	4.4%
297	Chagas Cardiomyopathy	4.4%
298	Tachycardia, Atrioventricular Nodal Reentry	4%
299	Tachycardia, Ectopic Atrial	4%
300	Tachycardia, Ectopic Junctional	4%
301	Sinus Tachycardia	4%
302	Torsades de Pointes	4%
303	Accelerated Idioventricular Rhythm	4%
304	Truncus Arteriosus, Persistent	4%
305	Carcinoid Heart Disease	3.9%
306	Romano-Ward Syndrome	3.9%
307	Subacute Bacterial Endocarditis	3.8%
308	Noonan Syndrome	3.8%
309	Hematoma, Subdural	3.5%
310	Hematoma, Epidural, Cranial	3.5%
311	Marfan Syndrome	3.4%
312	Dyspnea, Paroxysmal	3.3%
313	Sinus Arrest, Cardiac	3.3%
314	Hematoma, Subdural, Intracranial	3.1%
315	Hematoma, Subdural, Chronic	3.1%
316	Hematoma, Subdural, Acute	3.1%
317	Brain Hemorrhage, Traumatic	3%
318	MELAS Syndrome	2.9%
319	Dural Arteriovenous Fistula	2.7%
320	Fabry Disease	2.2%
321	Turner Syndrome	1.8%
322	Williams Syndrome	1.6%
323	Kartagener Syndrome	1.5%
324	Kearns-Sayre syndrome	1.2%

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