MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Exanthema

(UMLS:C0015230)

Definition:: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
UMLS ID:: C0015230
MeSH ID:: D005076

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.257

Synonym(s)

Exanthema

Breaking out - eruption

Cutaneous Eruption

Cutaneous eruption, NOS

Eruption

Eruption of skin

Exanthem

Exanthemata

RASH

10.

Rash

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acetaminophen	18377375	CTD
2	Alendronate	12730757	CTD
3	Allopurinol	11450872 26641773	CTD
4	Alprostadil	15966603	CTD
5	Amifostine	10688811 15064010	CTD
6	Aminoglutethimide	6123383 6180820 6691647	CTD
7	Amiodarone	3158188 9855346	CTD
8	Amlodipine	1839435 10940749	CTD
9	Amoxicillin-Potassium Clavulanate Combination	10369618 11390425 24329898	CTD
10	Amoxicillin	View details 1906097 7266720 11390425 24329898	CTD
11	Ampicillin	View details 636917 889204 4025903 5108409 6649724	CTD
12	Aspirin	6054600	CTD
13	Atenolol	1378155 2442551	CTD
14	Atracurium	2751916	CTD
15	Azathioprine	View details 15167706 15564886 15792824 16917406	CTD
16	Azithromycin	11247598 16943303	CTD
17	Aztreonam	2967033	CTD
18	Budesonide	10894975	CTD
19	Bupropion	12775141	CTD
20	Carbamazepine	View details 2327680 3225612 3579484 6462508 7806846 8398372 8600877 9072691 12005248 16204911 20485159 21428769	CTD
21	Carbimazole	2565460 15785249	CTD
22	Cefdinir	18377375	CTD
23	Cefixime	1906097	CTD
24	Ceftriaxone	3725639	CTD
25	Cefuroxime	10657721 15999477	CTD
26	Celecoxib	11390425 18583892	CTD
27	Cephaloridine	5108409	CTD
28	Cephalothin	View details 636917 4408153 5697520 6674550	CTD
29	Chlorambucil	19122478	CTD
30	Chloramphenicol	4800729	CTD
31	Chlorpromazine	4247303 4610613 7196160	CTD
32	Chlorpropamide	15251538	CTD
33	Cilastatin, Imipenem Drug Combination	9158321 9681765 10052540	CTD
34	Cimetidine	375397 7241779	CTD
35	Ciprofloxacin	View details 3555062 7596948 9201380 10688811 11476450 15827068	CTD
36	Clarithromycin	11390425 16627605	CTD
37	Clavulanic Acid	2791808	CTD
38	Clindamycin	142755 6295339 7089634	CTD
39	Clofibrate	7437867	CTD
40	Clonidine	3836300 9100429	CTD
41	Clopidogrel	16212151 20031738	CTD
42	Cloxacillin	11476450	CTD
43	Clozapine	1860384 15671137 16420089	CTD
44	Cocaine	8834352 20506546	CTD
45	Codeine	4025903	CTD
46	Cyclophosphamide	1677714 1679512	CTD
47	Cyclosporine	2566048 16114793	CTD
48	Cytarabine	View details 3463209 3784982 6941069 10491558 11745875	CTD
49	Dapsone	7481974 7973902 10812824	CTD
50	Deferasirox	17233848	CTD
51	Dexamethasone	10688811	CTD
52	Diatrizoate	3972525	CTD
53	Diazoxide	4299224	CTD
54	Diclofenac	2033230	CTD
55	Dicloxacillin	8742666	CTD
56	Didanosine	1974727	CTD
57	Diethylcarbamazine	87927	CTD
58	Diflunisal	2967101	CTD
59	Diltiazem	2699494	CTD
60	Diphenhydramine	7196160	CTD
61	Dipyrone	12445177	CTD
62	Disulfiram	2196696	CTD
63	Doxycycline	6268571	CTD
64	Dronedarone	19213680	CTD
65	Enalapril	2541310 6100872	CTD
66	Erlotinib Hydrochloride	21778302 27720938	CTD
67	Ethambutol	18583892	CTD
68	Everolimus	21306238	CTD
69	Fluconazole	10466905	CTD
70	Fluorescein	20002025	CTD
71	Flurbiprofen	4611579	CTD
72	Fluvoxamine	17644482	CTD
73	Formaldehyde	1683282	CTD
74	Gentamicins	6268571 6295339	CTD
75	Glutathione	8377599	CTD
76	Glyburide	16943303	CTD
77	Gold Sodium Thiomalate	4216306 6419855 6442055	CTD
78	Heroin	20506546	CTD
79	Hydroxychloroquine	10229401	CTD
80	Imatinib Mesylate	11549802	CTD
81	Imipramine	4610613	CTD
82	Indocyanine Green	7977601	CTD
83	Indomethacin	16943303	CTD
84	Iopamidol	2923308	CTD
85	Iothalamic Acid	4241506	CTD
86	Isoniazid	445303	CTD
87	Isotretinoin	7707116	CTD
88	Labetalol	672730 2873208	CTD
89	Lamivudine	11434632	CTD
90	Lamotrigine	View details 10448828 11052335 15517829 15845756 16442685 19031378	CTD
91	Leucovorin	6607976	CTD
92	Levamisole	View details 68226 282447 6451692 8018513	CTD
93	Lincomycin	7089634	CTD
94	Linezolid	19733945	CTD
95	Lisinopril	2442551 2442561 2550641	CTD
96	Lithium Carbonate	5273542	CTD
97	Lithium	7352540 15845756	CTD
98	Lovastatin	3055921	CTD
99	Maprotiline	791194 3805338	CTD
100	Medroxyprogesterone Acetate	6123383	CTD
101	Mephenytoin	1001284	CTD
102	Mercury Compounds	11390425	CTD
103	Meropenem	10381210	CTD
104	Mesna	1677714 1679512 16333822	CTD
105	Methicillin	4211170 4826627	CTD
106	Methimazole	View details 2523194 9773944 15785249 20168071	CTD
107	Methotrexate	1450620 1578459 6607976	CTD
108	Methyldopa	989134	CTD
109	Metoprolol	8554013 12090909	CTD
110	Micafungin	19148589	CTD
111	Minocycline	View details 303498 2780454 6268571 10573723 11728996	CTD
112	Mitotane	1517795	CTD
113	Morphine	6111570	CTD
114	Mycophenolic Acid	12937242	CTD
115	Nafcillin	7467307 9161625	CTD
116	Naltrexone	7340503	CTD
117	Naproxen	4595271 6850193	CTD
118	Nelfinavir	18176653	CTD
119	Nevirapine	View details 10476768 11450872 12971795 16038474 18422462 22750752 23590230 23947594 26626330	CTD
120	Niacin	11868059 16669604	CTD
121	Nicotine	8028537 10392670	CTD
122	Nifedipine	3716826 17612946	CTD
123	Nizatidine	7769203	CTD
124	Ofloxacin	11131957	CTD
125	Oxacillin	9161625 18307421	CTD
126	Oxcarbazepine	14634926 16816222	CTD
127	Ozone	19342399	CTD
128	Paclitaxel	View details 8708721 9007123 9774950 10955861	CTD
129	Pemetrexed	16360237	CTD
130	Penicillamine	View details 144507 310574 623127 769707 1833009 2938530 2952797 3905561 4048879 4119168 5488219 6216862 6451203 6451692 6460054 7342491 7362666 7452649 8463474	CTD
131	Penicillin G	287446 636917 16943303	CTD
132	Penicillin V	6268571	CTD
133	Pentamidine	2566818	CTD
134	Pentoxifylline	10688811	CTD
135	Pergolide	12601100	CTD
136	Phenobarbital	5282879	CTD
137	Phentermine	9799071	CTD
138	Phenylbutazone	647258 879127 6214246	CTD
139	Phenytoin	View details 132924 574201 817892 1678417 3276852 5108409 6693586 7280771 8521225 10698845 15229826 16750133 16900938	CTD
140	Piperacillin, Tazobactam Drug Combination	9017778	CTD
141	Piperacillin	2755033	CTD
142	Polymyxin B	31132327	CTD
143	Polythiazide	5086971	CTD
144	Prednisolone	View details 1268509 1677714 6419855 10812824	CTD
145	Prednisone	4211170 9017778 10894975	CTD
146	Procainamide	4122729	CTD
147	Prochlorperazine	4025903	CTD
148	Propofol	19420309	CTD
149	Propranolol	1268509 5086971	CTD
150	Propylthiouracil	View details 566489 6850193 9219172 15785249 16498810 17415292 22529993	CTD
151	Quinidine	3954525	CTD
152	Roxithromycin	11444584	CTD
153	Sirolimus	15102967 18044728 20815021	CTD
154	Sorafenib	18796127 20082451 20733337	CTD
155	Sulfasalazine	View details 1362531 4146729 6151882 12465141	CTD
156	Sulindac	7450449	CTD
157	Terbinafine	18833041	CTD
158	Thalidomide	View details 7579470 11840256 12525736 12644816 16445831	CTD
159	Thymidine	6607976	CTD
160	Ticlopidine	View details 1923914 2761587 8378945 9127122 10453975 16211203 20031738	CTD
161	Tobramycin	142755	CTD
162	Tocainide	3086580 3928215	CTD
163	Tramadol	12032009	CTD
164	Trimethoprim, Sulfamethoxazole Drug Combination	View details 85078 2572780 3260759 8717195 10190377 14703931 17164393 17297432	CTD
165	Trimethoprim	7481974	CTD
166	Valproic Acid	15229826 15517829	CTD
167	Vancomycin	View details 2596477 2861353 3934126 6219616 9825081 9874468 14742796 16114793 16943303 18607115 20391819	CTD
168	Varenicline	18574013	CTD
169	Vecuronium Bromide	2751916	CTD
170	Vincristine	9434832	CTD
171	Zidovudine	11434632	CTD
172	Zonisamide	15140322	CTD
173	afuresertib	25417902 30563934	CTD
174	amcinonide	8449700 10894975	CTD
175	bacampicillin	6352033	CTD
176	dichloralantipyrine	4247303	CTD
177	docosahexaenoyl-paclitaxel	19521262	CTD
178	efavirenz	11434632 16038474	CTD
179	fenclofenac	6419855	CTD
180	gemcitabine	10955861	CTD
181	isoniazid, pyrazinamide, rifampin drug combination	14755385	CTD
182	loracarbef	1621750	CTD
183	palbociclib	21610706	CTD
184	perhexiline maleate	861597	CTD
185	phendimetrazine	9799071	CTD
186	stronger neominophagen C	8377599	CTD
187	temsirolimus	20430774	CTD
188	trametinib	25417902	CTD
189	triclofos	4247303	CTD
190	trimethoprim sulfamethizole	4254939	CTD
191	urovision	4241506	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Pyoderma Gangrenosum	45.8%
2	Breast Diseases	42.9%
3	Dermatitis	42.9%
4	Facial Dermatoses	42.9%
5	Hair Diseases	42.9%
6	Hand Dermatoses	42.9%
7	keratoacanthoma	42.9%
8	Keratosis	42.9%
9	Nail Diseases	42.9%
10	Photosensitivity Disorders	42.9%
11	Prurigo	42.9%
12	Pyoderma	42.9%
13	Rosacea	42.9%
14	Sebaceous Gland Diseases	42.9%
15	Skin Diseases, Vesiculobullous	42.9%
16	Skin Ulcer	42.9%
17	Sweat Gland Diseases	42.9%
18	Skin Diseases, Papulosquamous	42.9%
19	Skin Diseases, Vascular	42.9%
20	Acneiform Eruptions	42.9%
21	Ocular Rosacea	42.9%
22	Subcorneal pustular dermatosis	42.9%
23	Erythematotelangiectatic Rosacea	42.9%
24	Papulopustular Rosacea	42.9%
25	Chronic Actinic Dermatitis	42.9%
26	Acne Vulgaris	40.9%
27	Contact Dermatitis	40.9%
28	Eczema	40.9%
29	Erythema Multiforme	40.9%
30	Intertrigo	40.9%
31	Neurodermatitis	40.9%
32	Rhinophyma	40.9%
33	Perioral Dermatitis	40.9%
34	Acne	40.9%
35	Lupus Erythematosus, Cutaneous	38.1%
36	Panniculitis	38.1%
37	Systemic Scleroderma	38.1%
38	Morphea	38.1%
39	Dermatitis, Phototoxic	37.2%
40	Pityriasis Lichenoides et Varioliformis Acuta	37.2%
41	Pityriasis Lichenoides	37.2%
42	Phototoxicity	37.2%
43	Foot Ulcer	37.1%
44	Dermatitis, Irritant	33.3%
45	Acne Conglobata	33.3%
46	Anhidrosis	31%
47	Cholesteatoma	31%
48	Pressure Ulcer	31%
49	Dermatitis Herpetiformis	31%
50	Folliculitis	31%
51	Foot Dermatoses	31%
52	Gynecomastia	31%
53	Hypertrichosis	31%
54	Hypohidrosis	31%
55	Hypotrichosis	31%
56	Leg Ulcer	31%
57	Miliaria	31%
58	Parakeratosis	31%
59	Parapsoriasis	31%
60	Pityriasis	31%
61	Psoriasis	31%
62	Sweet Syndrome	31%
63	Hidradenitis	31%
64	Onycholysis	31%
65	Miliaria Rubra	31%
66	Hyperpigmentation	31%
67	Lichenoid Eruptions	31%
68	Chloracne	31%
69	Acrodermatitis	30.5%
70	Sebaceous Gland Neoplasms	30.5%
71	Porokeratosis	30.5%
72	Gianotti-Crosti Syndrome	30.5%
73	Keratoderma, Palmoplantar	30.5%
74	Dermatitis, Atopic	30.3%
75	Epidermolysis Bullosa	30.3%
76	Foot Diseases	30%
77	Diaper Rash	29.7%
78	Dermatitis, Photoallergic	29.6%
79	Panniculitis, Lupus Erythematosus	29.3%
80	Skin Abnormalities	28.6%
81	Skin Diseases, Infectious	28.6%
82	Skin Neoplasms	28.6%
83	Pigmentation Disorders	28.6%
84	Lipomatosis	27.9%
85	Pruritus	27.9%
86	Erythema	27.9%
87	Necrolytic Migratory Erythema	27.9%
88	Cutaneous Fistula	27.9%
89	Nephrogenic Fibrosing Dermopathy	27.9%
90	Nephrogenic Systemic Fibrosis	27.9%
91	Necrobiosis Lipoidica Diabeticorum	27.5%
92	Urticaria Pigmentosa	27.3%
93	Lupus Erythematosus, Discoid	27.3%
94	Scleroderma, Limited	27.3%
95	Xeroderma Pigmentosum	27.1%
96	Dermatitis, Occupational	26.3%
97	Lichen Planus	25.4%
98	Melanosis	25.4%
99	Chloasma	25.4%
100	Pityriasis Rosea	25.4%
101	Pityriasis Rubra Pilaris	25.4%
102	Vitiligo	25.4%
103	Lichen Nitidus	25.4%
104	Dermatitis, Allergic Contact	25%
105	Papillon-Lefevre Disease	24.8%
106	Xeroderma	24.7%
107	Connective Tissue Diseases	23.1%
108	Erythema Induratum	22.8%
109	Acanthosis Nigricans	22.7%
110	Alopecia Areata	22.7%
111	Lentigo	22.7%
112	Erythema Infectiosum	22.4%
113	Cutis Laxa	22.4%
114	Erythema Nodosum	21.9%
115	Dermatomyositis	21.8%
116	Toxic Epidermal Necrolysis	21.1%
117	Stevens-Johnson Syndrome	21.1%
118	Acantholysis	20.9%
119	Breast Cyst	20.9%
120	Actinic keratosis	20.9%
121	Pemphigoid, Benign Mucous Membrane	20.9%
122	Pemphigus	20.9%
123	Piedra	20.9%
124	Sunburn	20.9%
125	Tinea Capitis	20.7%
126	Onychomycosis	20.7%
127	Mastocytosis	20.5%
128	Argyria	20.5%
129	Hirsutism	20.5%
130	Lactation Disorder	20.5%
131	Mastitis	20.5%
132	Urticaria	20.5%
133	Adiposis Dolorosa	20.2%
134	Ectodermal Dysplasia	20.2%
135	Pruritus Vulvae	20.2%
136	Aplasia Cutis Congenita	20.2%
137	Mastocytoma	20.1%
138	Pruritus Ani	20.1%
139	Hyperkeratosis, Epidermolytic	19.5%
140	Granuloma Annulare	19.3%
141	Pseudoxanthoma Elasticum	18.6%
142	Ecthyma	18.2%
143	Alopecia	17.2%
144	Sweating, Gustatory	17.2%
145	Androgenetic Alopecia	17.2%
146	Auriculotemporal Syndrome	17.2%
147	Lice Infestations	16.9%
148	Varicose Ulcer	16.9%
149	Breast Neoplasms, Male	16.9%
150	Triple Negative Breast Neoplasms	16.9%
151	Galactorrhea	16.7%
152	Hidradenitis Suppurativa	16.6%
153	Ichthyosis, X-Linked	15.8%
154	Behcet Syndrome	15.8%
155	Sjogren-Larsson Syndrome	15.7%
156	Dermatomycoses	15.5%
157	Mucocutaneous Lymph Node Syndrome	15.5%
158	Skin Diseases, Bacterial	15.5%
159	Tinea Pedis	15.5%
160	Lichen Planus, Oral	15.4%
161	Drug Eruptions	15.3%
162	Lipodystrophy	15.3%
163	Livedo Reticularis	15.3%
164	Malignant Atrophic Papulosis	15.3%
165	Polyarteritis Nodosa	15%
166	Takayasu Arteritis	15%
167	Collagen Diseases	14.3%
168	Mixed Connective Tissue Disease	14.3%
169	Mucinoses	14.3%
170	Albinism	13.8%
171	Erythema Chronicum Migrans	13.5%
172	Larva Migrans	12.8%
173	Leishmaniasis	12.8%
174	Molluscum Contagiosum	12.8%
175	Angioedema	12.7%
176	Onchocerciasis	12.6%
177	Chromoblastomycosis	12.5%
178	Dermatophytosis	12.5%
179	Nail-Patella Syndrome	12.5%
180	Sporotrichosis	12.5%
181	Tinea	12.5%
182	Tinea Versicolor	12.5%
183	Trichophytosis	12.5%
184	Hyalohyphomycosis	12.5%
185	Acute Generalized Exanthematous Pustulosis	12.4%
186	Porphyrias, Hepatic	12.3%
187	Mycetoma	12.3%
188	Leishmaniasis, Cutaneous	11.2%
189	Eczema Herpeticum	11.2%
190	Fusariosis	11.1%
191	Hereditary Angioedema Type III	10.4%
192	Hereditary Angioedema Types I and II	10.4%
193	Scleromyxedema	10.3%
194	Warts	10.3%
195	Exanthema Subitum	10.1%
196	Candidiasis, Chronic Mucocutaneous	10%
197	Cutaneous Candidiasis	10%
198	Cartilage Diseases	10%
199	Rheumatism	10%
200	Chondromalacia	10%
201	Erysipelas	9.9%
202	Serum Sickness	9.9%
203	Staphylococcal Skin Infections	9.9%
204	Variegate Porphyria	9.9%
205	Acute intermittent porphyria	9.9%
206	Porphyria Cutanea Tarda	9.9%
207	Erythrasma	9.9%
208	Carcinoma, Lobular	9.9%
209	Arthritis, Psoriatic	9.9%
210	Lupus Erythematosus, Systemic	9.5%
211	Overlap syndrome	9.5%
212	CREST Syndrome	9.4%
213	Angioedemas, Hereditary	9.1%
214	Epidermodysplasia Verruciformis	9%
215	Herpes Labialis	9%
216	Diabetic Foot	8.9%
217	Staphylococcal Scalded Skin Syndrome	8.8%
218	Peutz-Jeghers Syndrome	8.6%
219	carbuncle	8.2%
220	Condylomata Acuminata	7.5%
221	Furunculosis	7.4%
222	furuncle	7.4%
223	Giant Cell Arteritis	7.4%
224	Temporal Arteritis	7.4%
225	Impetigo	7.3%
226	Blastomycosis	7.1%
227	HIV-Associated Lipodystrophy Syndrome	7%
228	Mesenteric Panniculitis	7%
229	Panniculitis, Peritoneal	7%
230	Tietze's Syndrome	7%
231	Orbital Cellulitis	7%
232	Myxoid cyst	7%
233	Myxedema	6.8%
234	Dupuytren Contracture	6.8%
235	Rhinoscleroma	6.4%
236	Cellulitis	5.4%
237	Menkes Kinky Hair Syndrome	5.3%
238	Osteochondritis	5.3%
239	Polymyalgia Rheumatica	5.3%
240	Osteogenesis Imperfecta	5.1%
241	Keloid	5%
242	Rheumatoid Arthritis	4.2%
243	Rheumatoid Nodule	4.2%
244	Juvenile arthritis	4.2%
245	Lupus Nephritis	4%
246	Noonan Syndrome	3.8%
247	Laryngomalacia	3.5%
248	Pectus carinatum	3.4%
249	Marfan Syndrome	3.4%
250	Felty Syndrome	3.3%
251	Bronchomalacia	3.3%
252	Tracheomalacia	3.3%
253	Homocystinuria	3.3%
254	Rheumatoid Vasculitis	2.8%
255	Mucopolysaccharidosis III	2.7%
256	Sicca Syndrome	2.4%
257	Sjogren's Syndrome	2.4%
258	Mucopolysaccharidosis II	1.8%
259	Lupus Vasculitis, Central Nervous System	1.6%

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