MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pityriasis Rubra Pilaris

(UMLS:C0032027)

Definition:: A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug.
UMLS ID:: C0032027
MeSH ID:: D010916

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.859.600.685

Synonym(s)

Pityriasis Rubra Pilaris

Devergie

Devergie's disease

Lichen ruber acuminatus

PITYRIASIS RUBRA PILARIS

PRP - Pityriasis rubra pilaris

Pityriasis rubra pilaris

devergie's disease

pityriasis pilaris rubra

10.

pityriasis rubra pilaris

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ramipril	FAERS: 6		US FAERS
2	Carbamazepine	FAERS: 3		US FAERS
3	Ibuprofen	FAERS: 2		US FAERS
4	Amlodipine	FAERS: 1		US FAERS
5	Anastrozole	FAERS: 1		US FAERS
6	Desogestrel	FAERS: 1		US FAERS
7	Desogestrel	FAERS: 1		US FAERS
8	Dimethyl Fumarate	FAERS: 1		US FAERS
9	Fosamax plus D	FAERS: 1		US FAERS
10	Imiquimod	FAERS: 1		US FAERS
11	Isotretinoin	FAERS: 1		US FAERS
12	Ketoconazole	FAERS: 1		US FAERS
13	Thyroxine	FAERS: 1		US FAERS
14	Varenicline	FAERS: 1		US FAERS
15	apremilast	FAERS: 1		US FAERS
16	betamethasone-17,21-dipropionate	FAERS: 1		US FAERS
17	hydrochlorothiazide, lisinopril drug combination	FAERS: 1		US FAERS
18	reviparin	FAERS: 1		US FAERS
19	Acitretin			OFFSIDES
20	Etretinate		1477420	CTD
21	Methotrexate		5501901	CTD
22	pilsicainide			OFFSIDES
23	valdecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Pityriasis Rosea	48.4%
2	Pityriasis Lichenoides et Varioliformis Acuta	46.8%
3	Pityriasis Lichenoides	46.8%
4	Parapsoriasis	34.4%
5	Psoriasis	34.4%
6	Lichenoid Eruptions	34.4%
7	Breast Diseases	25.4%
8	Dermatitis	25.4%
9	Exanthema	25.4%
10	Facial Dermatoses	25.4%
11	Hair Diseases	25.4%
12	Hand Dermatoses	25.4%
13	keratoacanthoma	25.4%
14	Keratosis	25.4%
15	Nail Diseases	25.4%
16	Photosensitivity Disorders	25.4%
17	Prurigo	25.4%
18	Pyoderma	25.4%
19	Rosacea	25.4%
20	Sebaceous Gland Diseases	25.4%
21	Skin Diseases, Vesiculobullous	25.4%
22	Skin Ulcer	25.4%
23	Sweat Gland Diseases	25.4%
24	Skin Diseases, Vascular	25.4%
25	Acneiform Eruptions	25.4%
26	Ocular Rosacea	25.4%
27	Subcorneal pustular dermatosis	25.4%
28	Erythematotelangiectatic Rosacea	25.4%
29	Papulopustular Rosacea	25.4%
30	Chronic Actinic Dermatitis	25.4%
31	Lupus Erythematosus, Cutaneous	23%
32	Panniculitis	23%
33	Systemic Scleroderma	23%
34	Morphea	23%
35	Lichen Planus	22.6%
36	Lichen Nitidus	22.6%
37	Pyoderma Gangrenosum	22.3%
38	Acne Vulgaris	19.8%
39	Contact Dermatitis	19.8%
40	Eczema	19.8%
41	Erythema Multiforme	19.8%
42	Intertrigo	19.8%
43	Neurodermatitis	19.8%
44	Rhinophyma	19.8%
45	Perioral Dermatitis	19.8%
46	Acne	19.8%
47	Foot Diseases	18.1%
48	Skin Abnormalities	17.2%
49	Skin Diseases, Infectious	17.2%
50	Skin Neoplasms	17.2%
51	Pigmentation Disorders	17.2%
52	Lipomatosis	16.9%
53	Pruritus	16.9%
54	Erythema	16.9%
55	Necrolytic Migratory Erythema	16.9%
56	Cutaneous Fistula	16.9%
57	Nephrogenic Fibrosing Dermopathy	16.9%
58	Nephrogenic Systemic Fibrosis	16.9%
59	Connective Tissue Diseases	16.4%
60	Foot Ulcer	16.3%
61	Dermatitis Herpetiformis	15.1%
62	Dermatitis, Atopic	14.9%
63	Epidermolysis Bullosa	14.9%
64	Acrodermatitis	14.9%
65	Sebaceous Gland Neoplasms	14.9%
66	Porokeratosis	14.9%
67	Gianotti-Crosti Syndrome	14.9%
68	Keratoderma, Palmoplantar	14.9%
69	Anhidrosis	14.8%
70	Cholesteatoma	14.8%
71	Pressure Ulcer	14.8%
72	Folliculitis	14.8%
73	Foot Dermatoses	14.8%
74	Gynecomastia	14.8%
75	Hypertrichosis	14.8%
76	Hypohidrosis	14.8%
77	Hypotrichosis	14.8%
78	Leg Ulcer	14.8%
79	Miliaria	14.8%
80	Parakeratosis	14.8%
81	Sweet Syndrome	14.8%
82	Hidradenitis	14.8%
83	Onycholysis	14.8%
84	Miliaria Rubra	14.8%
85	Hyperpigmentation	14.8%
86	Chloracne	14.8%
87	Dermatitis, Phototoxic	14.5%
88	Phototoxicity	14.5%
89	Xeroderma Pigmentosum	13.4%
90	Dermatomyositis	13.4%
91	Lupus Erythematosus, Discoid	13.2%
92	Scleroderma, Limited	13.2%
93	Necrobiosis Lipoidica Diabeticorum	13.2%
94	Panniculitis, Lupus Erythematosus	13.1%
95	Dermatitis, Irritant	12.9%
96	Acne Conglobata	12.9%
97	Mastocytosis	12.5%
98	Urticaria Pigmentosa	12.1%
99	Xeroderma	12.1%
100	Cutis Laxa	11.8%
101	Dermatitis, Photoallergic	11.6%
102	Lichen Planus, Oral	11.6%
103	Erythema Induratum	10.3%
104	Dermatitis, Occupational	10.3%
105	Acantholysis	10.1%
106	Breast Cyst	10.1%
107	Actinic keratosis	10.1%
108	Pemphigoid, Benign Mucous Membrane	10.1%
109	Pemphigus	10.1%
110	Piedra	10.1%
111	Sunburn	10.1%
112	Erythema Infectiosum	10%
113	Ectodermal Dysplasia	9.9%
114	Aplasia Cutis Congenita	9.9%
115	Exanthema Subitum	9.9%
116	Argyria	9.9%
117	Hirsutism	9.9%
118	Lactation Disorder	9.9%
119	Mastitis	9.9%
120	Urticaria	9.9%
121	Adiposis Dolorosa	9.8%
122	Pruritus Vulvae	9.8%
123	Dermatitis, Allergic Contact	9.8%
124	Erythema Nodosum	9.7%
125	Mastocytoma	9.7%
126	Pruritus Ani	9.7%
127	Melanosis	9.7%
128	Chloasma	9.7%
129	Papillon-Lefevre Disease	9.7%
130	Vitiligo	9.7%
131	Pseudoxanthoma Elasticum	9.6%
132	Diaper Rash	9.6%
133	Arthritis, Psoriatic	9%
134	Granuloma Annulare	9%
135	Tinea Capitis	8.7%
136	Onychomycosis	8.7%
137	Collagen Diseases	8.5%
138	Mixed Connective Tissue Disease	8.5%
139	Mucinoses	8.5%
140	Toxic Epidermal Necrolysis	8.3%
141	Stevens-Johnson Syndrome	8.3%
142	Ecthyma	8.2%
143	Dermatomycoses	7.6%
144	Mucocutaneous Lymph Node Syndrome	7.6%
145	Skin Diseases, Bacterial	7.6%
146	Drug Eruptions	7.4%
147	Lipodystrophy	7.4%
148	Livedo Reticularis	7.4%
149	Malignant Atrophic Papulosis	7.4%
150	Polyarteritis Nodosa	7.3%
151	Takayasu Arteritis	7.3%
152	Acanthosis Nigricans	7.2%
153	Alopecia Areata	7.2%
154	Lentigo	7.2%
155	Behcet Syndrome	7.1%
156	Hyperkeratosis, Epidermolytic	6.9%
157	Ichthyosis, X-Linked	6.9%
158	Sjogren-Larsson Syndrome	6.8%
159	Alopecia	6.7%
160	Sweating, Gustatory	6.7%
161	Androgenetic Alopecia	6.7%
162	Auriculotemporal Syndrome	6.7%
163	Lice Infestations	6.5%
164	Varicose Ulcer	6.5%
165	Hidradenitis Suppurativa	6.5%
166	Breast Neoplasms, Male	6.5%
167	Triple Negative Breast Neoplasms	6.5%
168	Galactorrhea	6.5%
169	Albinism	6.2%
170	Nail-Patella Syndrome	6.1%
171	Erythema Chronicum Migrans	6.1%
172	Porphyrias, Hepatic	6%
173	Cartilage Diseases	6%
174	Rheumatism	6%
175	Chondromalacia	6%
176	Lupus Erythematosus, Systemic	5.7%
177	Overlap syndrome	5.7%
178	Tinea Pedis	5.6%
179	Larva Migrans	5%
180	Leishmaniasis	5%
181	Molluscum Contagiosum	5%
182	Angioedema	5%
183	Onchocerciasis	4.9%
184	Scleromyxedema	4.9%
185	Chromoblastomycosis	4.9%
186	Dermatophytosis	4.9%
187	Sporotrichosis	4.9%
188	Tinea	4.9%
189	Tinea Versicolor	4.9%
190	Trichophytosis	4.9%
191	Hyalohyphomycosis	4.9%
192	Mycetoma	4.9%
193	Acute Generalized Exanthematous Pustulosis	4.8%
194	Dupuytren Contracture	4.1%
195	Warts	4.1%
196	Candidiasis, Chronic Mucocutaneous	3.9%
197	Cutaneous Candidiasis	3.9%
198	Erysipelas	3.9%
199	Serum Sickness	3.9%
200	Staphylococcal Skin Infections	3.9%
201	Variegate Porphyria	3.9%
202	Acute intermittent porphyria	3.9%
203	Porphyria Cutanea Tarda	3.9%
204	Erythrasma	3.9%
205	Carcinoma, Lobular	3.9%
206	CREST Syndrome	3.7%
207	Giant Cell Arteritis	3.7%
208	Temporal Arteritis	3.7%
209	Leishmaniasis, Cutaneous	3.6%
210	Eczema Herpeticum	3.6%
211	Fusariosis	3.6%
212	Mesenteric Panniculitis	3.4%
213	Panniculitis, Peritoneal	3.4%
214	Tietze's Syndrome	3.4%
215	Orbital Cellulitis	3.4%
216	Myxoid cyst	3.4%
217	Cellulitis	3.3%
218	Myxedema	3.3%
219	Hereditary Angioedema Type III	3%
220	Hereditary Angioedema Types I and II	3%
221	Angioedemas, Hereditary	3%
222	Epidermodysplasia Verruciformis	2.9%
223	Herpes Labialis	2.9%
224	Diabetic Foot	2.9%
225	Staphylococcal Scalded Skin Syndrome	2.9%
226	Blastomycosis	2.8%
227	HIV-Associated Lipodystrophy Syndrome	2.8%
228	Menkes Kinky Hair Syndrome	2.6%
229	Osteochondritis	2.6%
230	Polymyalgia Rheumatica	2.6%
231	Rhinoscleroma	2.5%
232	Osteogenesis Imperfecta	2.5%
233	Peutz-Jeghers Syndrome	2.5%
234	Condylomata Acuminata	2.5%
235	Furunculosis	2.4%
236	Keloid	2.4%
237	furuncle	2.4%
238	Impetigo	2.4%
239	carbuncle	2.4%
240	Noonan Syndrome	2.4%
241	Marfan Syndrome	2.1%
242	Rheumatoid Arthritis	2%
243	Juvenile arthritis	2%
244	Homocystinuria	2%
245	Lupus Nephritis	1.9%
246	Laryngomalacia	1.7%
247	Pectus carinatum	1.7%
248	Rheumatoid Nodule	1.6%
249	Felty Syndrome	1.3%
250	Bronchomalacia	1.3%
251	Tracheomalacia	1.3%
252	Rheumatoid Vasculitis	1.1%
253	Mucopolysaccharidosis III	1.1%
254	Sicca Syndrome	0.9%
255	Sjogren's Syndrome	0.9%
256	Lupus Vasculitis, Central Nervous System	0.8%
257	Mucopolysaccharidosis II	0.7%

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