MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukemia, Large Granular Lymphocytic

(UMLS:C1522378)

Definition:: A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.
UMLS ID:: C1522378
MeSH ID:: D054066

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.337.428.580.049

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.515.560.575.049

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.683.515.528.582.049

Synonym(s)

Leukemia, Large Granular Lymphocytic

LGL leukemia

LGLL - Large granular lymphocytic leukaemia

LGLL - Large granular lymphocytic leukemia

Large granular lymphocytic leukaemia

Large granular lymphocytic leukemia

Large granular lymphocytosis

large granular lymphocytic granuloma

large granular lymphocytosis

10.

leukemia lymphocytic chronic large granular lymphocytic

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Sulfasalazine		12587019	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Leukemia, B-Cell	36%
2	Lymphoma	26.6%
3	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	23.8%
4	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	23.8%
5	Tumor Lysis Syndrome	22.7%
6	Autoimmune Lymphoproliferative Syndrome	18.8%
7	Sezary Syndrome	18.4%
8	Leukemia, Plasma Cell	17.4%
9	Infectious Mononucleosis	17.4%
10	Composite Lymphoma	16.6%
11	Plasmacytoma	16.2%
12	Hodgkin Disease	15.3%
13	Lymphoma, Non-Hodgkin	15.3%
14	Primary amyloidosis	15.1%
15	Heavy Chain Disease	14.3%
16	Sarcoidosis	14.1%
17	Histiocytic Disorders, Malignant	13.8%
18	Lymphangioleiomyomatosis	13.7%
19	Agammaglobulinemia	13.4%
20	Waldenstrom Macroglobulinemia	12.8%
21	Multiple Myeloma	12.8%
22	Leukemia, Experimental	12%
23	Lymphocele	12%
24	Granuloma	11.5%
25	Adenitis	11%
26	Histiocytosis	11%
27	Lymphadenitis	11%
28	Lymphangitis	11%
29	Lymphedema	11%
30	Neoplasms, Germ Cell and Embryonal	11%
31	Neoplasms, Glandular and Epithelial	11%
32	Splenic Diseases	11%
33	Thymus Hyperplasia	11%
34	Pseudolymphoma	11%
35	Lymphadenopathy	11%
36	Germ Cell Cancer	11%
37	Paraproteinemias	10.5%
38	Thymus Neoplasms	10.5%
39	Leukemia, Radiation-Induced	10.4%
40	Lymphoma, Follicular	9.8%
41	T-Cell Lymphoma	9.8%
42	Mantle cell lymphoma	9.8%
43	Neuroectodermal Tumors	9.7%
44	Sarcoma, Myeloid	9.6%
45	Lymphatic Abnormalities	9%
46	Thymoma	8.9%
47	Transfusion Reaction	8.9%
48	Hypotensive Transfusion Reaction	8.9%
49	Hypergammaglobulinemia	8.9%
50	Neoplasms, Neuroepithelial	8.8%
51	Gliomatosis cerebri	8.8%
52	Leukemia L1210	8.4%
53	Leukemia P388	8.4%
54	Monoclonal Gammopathy of Undetermined Significance	8.3%
55	Lymphomatoid Granulomatosis	8.3%
56	Lymphangiectasis, Intestinal	8.1%
57	Splenic Neoplasms	7.9%
58	Carcinosarcoma	7.7%
59	Hemangiosarcoma	7.7%
60	Malignant histiocytosis	7.7%
61	lymphangiosarcoma	7.7%
62	Histiocytic sarcoma	7.7%
63	Leukemia, Myelomonocytic, Chronic	7.7%
64	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.7%
65	Mucocutaneous Lymph Node Syndrome	7.4%
66	Meningioma	7.4%
67	melanoma	7.2%
68	Autoimmune Diseases	7.2%
69	Hamartoma	7.2%
70	Hypersensitivity	7.2%
71	Immunologic Deficiency Syndromes	7.2%
72	Neoplasms, Hormone-Dependent	7.2%
73	Neoplasms, Multiple Primary	7.2%
74	Paraneoplastic Syndromes	7.2%
75	Precancerous Conditions	7.2%
76	Neoplasms, Second Primary	7.2%
77	Immune reconstitution syndrome	7.2%
78	Immune Reconstitution Inflammatory Syndrome	7.2%
79	Lymphoma, T-Cell, Cutaneous	7.1%
80	Lymphoma, AIDS-Related	7.1%
81	Enteropathy-Associated T-Cell Lymphoma	7.1%
82	Primary Effusion Lymphoma	7.1%
83	Sarcoidosis, Pulmonary	6.8%
84	Trophoblastic Neoplasms	6.6%
85	Carcinoma 256, Walker	6.5%
86	Adenoma	6%
87	Ameloblastoma	6%
88	Angiokeratoma	6%
89	Carcinoma	6%
90	Chordoma	6%
91	Elephantiasis	6%
92	Hemangioma	6%
93	hemangiopericytoma	6%
94	Hypersplenism	6%
95	Lymphangioma	6%
96	Mesenchymoma	6%
97	Nevus	6%
98	Teratoma	6%
99	Hepatoblastoma	6%
100	Mixed Tumor, Mullerian	6%
101	Germinoma	6%
102	Teratocarcinoma	6%
103	Angiofibroma	6%
104	Elephantiasis Nostras Verrucosa	6%
105	Sarcoma	6%
106	Epithelioma	6%
107	Hematologic Neoplasms	6%
108	Carcinoma, Ehrlich Tumor	5.9%
109	Dermoid Cyst	5.9%
110	Carcinoma, Lewis Lung	5.9%
111	Cyst	5.8%
112	Neoplastic Processes	5.8%
113	Neoplastic Syndromes, Hereditary	5.8%
114	Pregnancy Complications, Neoplastic	5.8%
115	Mycosis Fungoides	5.8%
116	Lymphomatoid Papulosis	5.8%
117	Plasmablastic lymphoma	5.8%
118	Basal cell carcinoma	5.8%
119	Carcinoma, Papillary	5.8%
120	Squamous cell carcinoma	5.8%
121	Chondrosarcoma	5.8%
122	Craniopharyngioma	5.8%
123	Cystadenoma	5.8%
124	leiomyosarcoma	5.8%
125	liposarcoma	5.8%
126	Mesothelioma	5.8%
127	synovial sarcoma	5.8%
128	Neuroectodermal Tumor, Melanotic	5.8%
129	Angiomyolipoma	5.8%
130	Clear Cell Sarcoma of Soft Tissue	5.8%
131	Alveolar Soft Part Sarcoma	5.8%
132	Neuroendocrine Tumors	5.8%
133	Carcinoma, Basal Cell	5.8%
134	Neoplasms, Experimental	5.7%
135	Adenoma, Acidophil	5.6%
136	Ganglioneuroma	5.6%
137	Glioma	5.6%
138	Malignant Glioma	5.6%
139	Melanoma, Experimental	5.4%
140	Burkitt Lymphoma	5.4%
141	Medulloblastoma	5.3%
142	Leukemia, Myeloid, Chronic-Phase	5.1%
143	Splenic Infarction	4.9%
144	Sarcoma, Experimental	4.9%
145	Histiocytosis, Langerhans-Cell	4.9%
146	Cryoglobulinemia	4.8%
147	Multiple Endocrine Neoplasia	4.8%
148	Neoplasms, Radiation-Induced	4.8%
149	Endometrial Stromal Sarcoma	4.8%
150	Cystadenocarcinoma	4.8%
151	Fibrosarcoma	4.8%
152	Osteosarcoma	4.8%
153	Mucoepidermoid Carcinoma	4.8%
154	Carcinoid Tumor	4.8%
155	Neurilemmoma	4.8%
156	Hutchinson's Melanotic Freckle	4.8%
157	Melanoma, Amelanotic	4.8%
158	Glomerulonephritis, Membranoproliferative	4.7%
159	Choriocarcinoma	4.6%
160	Carcinoma, Lobular	4.6%
161	Thrombocytopenic purpura	4.5%
162	Acanthoma	4.5%
163	Autoimmune thrombocytopenia	4.3%
164	Immune thrombocytopenic purpura	4.3%
165	Adenofibroma	4.3%
166	Fibroadenoma	4.3%
167	Malignant Fibrous Histiocytoma	4.3%
168	POEMS Syndrome	4.2%
169	Splenic Rupture	4.2%
170	Disseminated Intravascular Coagulation	4.1%
171	Protein S Deficiency	4.1%
172	Bone Marrow Neoplasms	4.1%
173	Astrocytoma	4%
174	Ependymoma	4%
175	oligodendroglioma	4%
176	Ganglioglioma	4%
177	gliosarcoma	4%
178	Anaplastic astrocytoma	4%
179	Anaplastic Oligodendroglioma	4%
180	Lymphopenia	3.9%
181	Retinoblastoma	3.9%
182	Paraneoplastic Encephalomyelitis	3.9%
183	Nephroblastoma	3.8%
184	Mammary Neoplasms, Experimental	3.8%
185	Mastocytosis	3.8%
186	Transfusion-Related Acute Lung Injury	3.8%
187	Bowen's Disease	3.8%
188	Paraganglioma	3.8%
189	Rhabdomyosarcoma	3.8%
190	Giant Cell Tumor of Bone	3.8%
191	Tuberous Sclerosis	3.8%
192	Abdominal Neoplasms	3.7%
193	Anemia	3.7%
194	Blood Coagulation Disorders	3.7%
195	Blood Platelet Disorders	3.7%
196	Bone Marrow Diseases	3.7%
197	Erythroplasia	3.7%
198	Follicular cyst	3.7%
199	Head and Neck Neoplasms	3.7%
200	Hemorrhagic Disorders	3.7%
201	Immune Complex Diseases	3.7%
202	Leukocyte Disorders	3.7%
203	Methemoglobinemia	3.7%
204	Mucocele	3.7%
205	Pancytopenia	3.7%
206	Pilonidal Cyst	3.7%
207	Polycythemia	3.7%
208	Soft Tissue Neoplasms	3.7%
209	Sulfhemoglobinemia	3.7%
210	Thoracic Neoplasms	3.7%
211	Thyroglossal Cyst	3.7%
212	Antiphospholipid Syndrome	3.7%
213	Synovial Cyst	3.7%
214	Thrombophilia	3.7%
215	Latex allergy	3.7%
216	Erythrocytosis	3.7%
217	Aberrant Crypt Foci	3.7%
218	Adenocarcinoma	3.6%
219	Carcinoma in Situ	3.6%
220	Carcinoma, Transitional Cell	3.6%
221	Phyllodes Tumor	3.6%
222	Dysgerminoma	3.6%
223	Hemangioendothelioma	3.6%
224	Lipoma	3.6%
225	Lymphohistiocytosis, Hemophagocytic	3.6%
226	Myoma	3.6%
227	Myxoma	3.6%
228	Neuroma	3.6%
229	Papilloma	3.6%
230	Pseudomyxoma Peritonei	3.6%
231	Seminoma	3.6%
232	Papillomatosis	3.6%
233	Angiolipoma	3.6%
234	Myelolipoma	3.6%
235	Neoplasms, Bone Tissue	3.6%
236	Neoplasms, Fibrous Tissue	3.6%
237	Smooth Muscle Tumor	3.6%
238	Adenomatosis, Pulmonary	3.6%
239	Adenomatous Polyps	3.6%
240	Carcinoma, Large Cell	3.6%
241	Carcinoma, Small Cell	3.6%
242	Desmoplastic Small Round Cell Tumor	3.6%
243	Schnitzler Syndrome	3.6%
244	Erdheim-Chester Disease	3.6%
245	Chondroma	3.6%
246	Enchondroma	3.6%
247	Malignant Carcinoid Syndrome	3.6%
248	Sarcoma 180	3.5%
249	Thrombocythemia, Essential	3.5%
250	Dermatofibrosarcoma	3.3%
251	Dermatofibrosarcoma Protuberans	3.3%
252	Neurofibrosarcoma	3.3%
253	Hemangioma, Cavernous	3.2%
254	Glioblastoma	3.2%
255	Neuroblastoma	3.2%
256	Glioblastoma Multiforme	3.2%
257	Basal Cell Nevus Syndrome	3.1%
258	Digestive System Neoplasms	3.1%
259	Endocrine Gland Neoplasms	3.1%
260	Eye Neoplasms	3.1%
261	Nervous System Neoplasms	3.1%
262	Environmental Illness	3.1%
263	Mesoblastic Nephroma	3%
264	Thrombasthenia	3%
265	Antithrombin III Deficiency	3%
266	Protein C Deficiency	3%
267	Bone neoplasms	3%
268	Leukoplakia	3%
269	Lupus Erythematosus, Systemic	3%
270	Pancreatic Cyst	3%
271	Pregnancy Complications, Hematologic	3%
272	Skin Neoplasms	3%
273	Overlap syndrome	3%
274	Addison Disease	3%
275	Barrett Esophagus	3%
276	Breast Cyst	3%
277	Actinic keratosis	3%
278	Mediastinal Cyst	3%
279	Neoplasm Invasiveness	3%
280	Neoplasm Metastasis	3%
281	Neoplasm Recurrence, Local	3%
282	Parovarian Cyst	3%
283	Pemphigus	3%
284	Pericardial Cyst	3%
285	Thymic Cyst	3%
286	Carcinogenesis	3%
287	Autoimmune thyroiditis	3%
288	Myxoid cyst	3%
289	Primary Adrenal Insufficiency	3%
290	Metastasis	3%
291	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.9%
292	Autoimmune hepatitis	2.9%
293	Mastocytosis, Systemic	2.9%
294	Pheochromocytoma	2.8%
295	Alveolar rhabdomyosarcoma	2.8%
296	Hepatocellular Adenoma	2.8%
297	Ganglioneuroblastoma	2.8%
298	Polycythemia Vera	2.7%
299	Wiskott-Aldrich Syndrome	2.7%
300	Vitamin K Deficiency	2.7%
301	Carcinoma, Pancreatic Ductal	2.7%
302	Multiple Endocrine Neoplasia Type 1	2.6%
303	Hydrops Fetalis	2.6%
304	Carcinoid Heart Disease	2.6%
305	Thrombocytosis	2.6%
306	Job Syndrome	2.6%
307	Kernicterus	2.6%
308	Afibrinogenemia	2.5%
309	Factor VII Deficiency	2.5%
310	Factor X Deficiency	2.5%
311	Factor XII Deficiency	2.5%
312	Hemophilia A	2.5%
313	Activated Protein C Resistance	2.5%
314	Factor II deficiency	2.5%
315	Factor VIII Deficiency	2.5%
316	Factor V deficiency	2.5%
317	Factor XI Deficiency	2.5%
318	Hypoprothrombinemias	2.5%
319	Acoustic Neuroma	2.5%
320	Latent Autoimmune Diabetes in Adults	2.5%
321	Dermatitis Herpetiformis	2.5%
322	Kounis Syndrome	2.5%
323	Liver Neoplasms, Experimental	2.5%
324	HIV Infections	2.5%
325	Sturge-Weber Syndrome	2.5%
326	Corpus Luteum Cyst	2.4%
327	Ovarian Cysts	2.4%
328	Eosinophilic Granuloma	2.4%
329	Splenosis	2.4%
330	Gastrointestinal Stromal Tumors	2.4%
331	Prolactinoma	2.4%
332	Growth Hormone-Secreting Pituitary Adenoma	2.4%
333	neurofibroma	2.4%
334	Hydatidiform Mole	2.4%
335	Adenoid Cystic Carcinoma	2.4%
336	fibroma	2.4%
337	Fibromatosis	2.4%
338	Osteoblastoma	2.4%
339	Osteoma	2.4%
340	Rhabdomyoma	2.4%
341	Chondromatosis	2.4%
342	Adenocarcinoma, Clear Cell	2.4%
343	Cholangiocarcinoma	2.4%
344	Cervical Intraepithelial Neoplasia	2.4%
345	Hemangioblastoma	2.4%
346	Lymphoma, Extranodal NK-T-Cell	2.4%
347	Lambert-Eaton Myasthenic Syndrome	2.4%
348	Parathyroid Neoplasms	2.4%
349	Peritoneal Neoplasms	2.4%
350	Thyroid Neoplasm	2.4%
351	Thyroid carcinoma	2.4%
352	Optic Nerve Glioma	2.3%
353	Adenomatous Polyposis Coli	2.2%
354	Chronic granulomatous disease	2.2%
355	Rheumatoid Arthritis	2.1%
356	Choledochal Cyst	2.1%
357	Juvenile arthritis	2.1%
358	granulosa cell tumor	2.1%
359	Carcinoma, Ovarian Epithelial	2.1%
360	Graves Disease	2.1%
361	Pancreatic Neoplasm	2.1%
362	Peutz-Jeghers Syndrome	2.1%
363	Anti-Glomerular Basement Membrane Disease	2.1%
364	Vipoma	2.1%
365	Asthma, Aspirin-Induced	2%
366	anaphylaxis	2%
367	Anemia, Hemolytic	2%
368	Anemia, Macrocytic	2%
369	Eosinophilia	2%
370	Food Allergy	2%
371	Hypoproteinemia	2%
372	Leukopenia	2%
373	Retroperitoneal Neoplasms	2%
374	Thrombocytopenia	2%
375	Leukostasis	2%
376	MYELODYSPLASTIC SYNDROME	2%
377	Anaphylactic shock	2%
378	Mastocytoma	1.9%
379	Hemoglobinuria, Paroxysmal	1.9%
380	Leukemoid Reaction	1.9%
381	Tracheal Neoplasms	1.9%
382	Leukoplakia, Oral	1.9%
383	Paraneoplastic Cerebellar Degeneration	1.8%
384	Serum Sickness	1.8%
385	Fibromatosis, Aggressive	1.8%
386	Fibromatosis, Abdominal	1.8%
387	Klatskin Tumor	1.8%
388	insulinoma	1.8%
389	Purpura, Thrombotic Thrombocytopenic	1.7%
390	Respiratory Hypersensitivity	1.7%
391	Nasopharyngeal carcinoma	1.7%
392	Denys-Drash Syndrome	1.6%
393	Anemia, Neonatal	1.6%
394	Leukocytosis	1.6%
395	Mouth Neoplasms	1.6%
396	Pelger-Huet Anomaly	1.6%
397	Sick Building Syndrome	1.6%
398	Central Nervous System Neoplasms	1.6%
399	Pleocytosis	1.6%
400	Multiple Chemical Sensitivity	1.6%
401	Vascular Neoplasms	1.6%
402	Esophageal Neoplasms	1.6%
403	Myelitis, Transverse	1.6%
404	Anemia, Sickle Cell	1.6%
405	Thalassemia	1.6%
406	Genital Neoplasms, Female	1.6%
407	Pancreatic Pseudocyst	1.6%
408	Urticaria	1.6%
409	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
410	Limbic Encephalitis	1.6%
411	HTLV-I Infections	1.6%
412	Lymphatic Metastasis	1.6%
413	Neoplasms, Unknown Primary	1.6%
414	Leukemic Infiltration	1.6%
415	Breast Neoplasms, Male	1.6%
416	Neoplasm Micrometastasis	1.6%
417	Triple Negative Breast Neoplasms	1.6%
418	Anemia, Diamond-Blackfan	1.6%
419	Adrenocortical carcinoma	1.6%
420	Leydig Cell Tumor	1.5%
421	Gastrinoma	1.5%
422	Glucagonoma	1.5%
423	Ataxia Telangiectasia	1.5%
424	Testicular Neoplasms	1.5%
425	Renal Cell Carcinoma	1.4%
426	Papillary Renal Cell Carcinoma	1.4%
427	Thyroid Nodule	1.4%
428	Adrenal Gland Neoplasms	1.4%
429	Gastrointestinal Neoplasms	1.4%
430	Genital Neoplasms, Male	1.4%
431	Liver neoplasms	1.4%
432	Uveal Neoplasms	1.4%
433	Myasthenia Gravis	1.4%
434	Urologic Neoplasms	1.4%
435	Uveomeningoencephalitic Syndrome	1.4%
436	Drug Eruptions	1.4%
437	Ecchymosis	1.4%
438	Petechiae	1.4%
439	Purpura	1.4%
440	Sebaceous Gland Neoplasms	1.4%
441	Spinal Neoplasms	1.4%
442	Xeroderma Pigmentosum	1.4%
443	Granulomatosis with polyangiitis	1.3%
444	Dermatitis, Allergic Contact	1.3%
445	HIV Seropositivity	1.3%
446	Polycystic Ovary Syndrome	1.3%
447	Carcinoma, Endometrioid	1.3%
448	Opsoclonus-Myoclonus Syndrome	1.3%
449	Dupuytren Contracture	1.2%
450	Purpura, Hyperglobulinemic	1.2%
451	Urticaria Pigmentosa	1.2%
452	Primary Myelofibrosis	1.2%
453	Agranulocytosis	1.2%
454	Anemia, Megaloblastic	1.2%
455	Lymphocytosis	1.2%
456	Myelofibrosis	1.2%
457	Myeloid Metaplasia	1.2%
458	Milk Allergy	1.2%
459	Hypoalbuminemia	1.2%
460	Wheat Hypersensitivity	1.2%
461	Hypereosinophilic syndrome	1.2%
462	bone marrow fibrosis	1.2%
463	Thrombotic Microangiopathies	1.2%
464	Stiff-Person Syndrome	1.2%
465	Polyradiculoneuropathy	1.2%
466	Polyradiculoneuritis	1.2%
467	Acquired Immunodeficiency Syndrome	1.2%
468	AIDS related complex	1.2%
469	Felty Syndrome	1.2%
470	Lupus Nephritis	1.1%
471	Hemolytic-Uremic Syndrome	1.1%
472	Myasthenia Gravis, Autoimmune, Experimental	1.1%
473	Waterhouse-Friderichsen Syndrome	1.1%
474	AIDS-Related Opportunistic Infections	1%
475	Vasculitis, Central Nervous System	1%
476	Sickle Cell Trait	1%
477	Dermatitis, Atopic	1%
478	ovarian neoplasm	1%
479	HIV Wasting Syndrome	1%
480	Rheumatoid Vasculitis	1%
481	AIDS Dementia Complex	1%
482	AIDS-Associated Nephropathy	1%
483	Nose Neoplasms	1%
484	Meningeal Neoplasms	1%
485	Pituitary Adenoma	0.9%
486	Pituitary Neoplasms	0.9%
487	Lupus Vasculitis, Central Nervous System	0.9%
488	Fanconi Anemia	0.9%
489	Sicca Syndrome	0.9%
490	Sjogren's Syndrome	0.9%
491	Palatal Neoplasms	0.9%
492	HIV-Associated Lipodystrophy Syndrome	0.9%
493	Ear Neoplasms	0.8%
494	Eyelid Neoplasms	0.8%
495	Lung Neoplasms	0.8%
496	Pleural Neoplasms	0.8%
497	Eosinophilia-Myalgia Syndrome	0.8%
498	Acute Chest Syndrome	0.8%
499	Zollinger-Ellison syndrome	0.8%
500	Angioedema	0.8%
501	Cell Transformation, Viral	0.8%
502	Brain Neoplasms	0.8%
503	Multiple Sclerosis	0.8%
504	Salivary Gland Neoplasms	0.8%
505	Shwartzman Phenomenon	0.8%
506	Spinal Cord Neoplasms	0.8%
507	Tongue Neoplasms	0.8%
508	Scurvy	0.8%
509	Uterine Neoplasms	0.8%
510	Vaginal Neoplasms	0.8%
511	Vulvar Neoplasms	0.8%
512	Purpura Fulminans	0.8%
513	Uterine Cancer	0.8%
514	Acute Generalized Exanthematous Pustulosis	0.8%
515	Fallopian Tube Neoplasms	0.8%
516	Neutropenia	0.8%
517	Atypical Hemolytic Uremic Syndrome	0.8%
518	Neuromyelitis Optica	0.7%
519	Leukoencephalitis, Acute Hemorrhagic	0.7%
520	Niemann-Pick Disease, Type C	0.7%
521	Pharyngeal Neoplasms	0.7%
522	Asthma	0.7%
523	Central Nervous System Cysts	0.7%
524	Bile Duct Neoplasms	0.7%
525	gallbladder neoplasm	0.7%
526	Intestinal Neoplasms	0.7%
527	Penile Neoplasms	0.7%
528	Prostatic Neoplasms	0.7%
529	Stomach Neoplasms	0.7%
530	Encephalomyelitis, Acute Disseminated	0.7%
531	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.7%
532	Erythema Nodosum	0.7%
533	Neuritis, Autoimmune, Experimental	0.7%
534	Dermatitis, Photoallergic	0.7%
535	Pulmonary Eosinophilia	0.6%
536	Eosinophilic Pneumonia	0.6%
537	Meningeal Carcinomatosis	0.6%
538	Anemia, Pernicious	0.6%
539	Laryngeal neoplasm	0.6%
540	Aspergillosis, Allergic Bronchopulmonary	0.6%
541	Guillain-Barre Syndrome	0.6%
542	Bladder Neoplasm	0.6%
543	Kidney Neoplasm	0.6%
544	Ureteral Neoplasms	0.6%
545	Urethral Neoplasms	0.6%
546	Febrile Neutropenia	0.6%
547	Bronchial Neoplasms	0.5%
548	Asthma, Exercise-Induced	0.5%
549	Status Asthmaticus	0.5%
550	Multiple Pulmonary Nodules	0.5%
551	Toxic Epidermal Necrolysis	0.5%
552	Stevens-Johnson Syndrome	0.5%
553	Supratentorial Neoplasms	0.5%
554	Multiple Sclerosis, Chronic Progressive	0.5%
555	Multiple Sclerosis, Relapsing-Remitting	0.5%
556	Endometrial Neoplasms	0.5%
557	Pseudoxanthoma Elasticum	0.5%
558	Giant Cell Arteritis	0.5%
559	Temporal Arteritis	0.5%
560	Asthma, Occupational	0.5%
561	Farmer's Lung	0.5%
562	Angioedemas, Hereditary	0.5%
563	Hypopharyngeal Neoplasms	0.5%
564	Pleural Effusion, Malignant	0.5%
565	Hypopharyngeal Cancer	0.5%
566	Hay fever	0.5%
567	Rhinitis, Allergic, Perennial	0.5%
568	Parotid Neoplasms	0.5%
569	Prostatic Neoplasms, Castration-Resistant	0.5%
570	Nelson Syndrome	0.5%
571	Cecal Neoplasms	0.4%
572	Duodenal Neoplasms	0.4%
573	Hereditary Angioedema Type III	0.4%
574	Hereditary Angioedema Types I and II	0.4%
575	Brain Stem Neoplasms	0.4%
576	Nasopharyngeal Neoplasms	0.4%
577	Colorectal Neoplasms	0.4%
578	Tonsillar Neoplasms	0.3%
579	Cerebellar Neoplasms	0.3%
580	Choroid Plexus Papilloma	0.3%
581	Paranasal Sinus Neoplasms	0.3%
582	Radicular Cyst	0.3%
583	Appendiceal Neoplasms	0.3%
584	Colonic Neoplasms	0.3%
585	Rectal Neoplasms	0.3%
586	Miller Fisher Syndrome	0.3%
587	Maxillary Sinus Neoplasms	0.2%
588	Anus Neoplasms	0.2%
589	Sigmoid Neoplasms	0.2%

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