MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ischemic contracture

(UMLS:C0334142)

UMLS ID:: C0334142
MeSH ID:: D054061

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.323.734|C05.651.180.531|C05.651.197.734

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.303.531

Synonym(s)

Ischemic contracture

Ischaemic contracture

ischaemic contracture

ischemic contracture

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Secobarbital		5467300	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hip Contracture	44.4%
2	Anterior Compartment Syndrome	40%
3	Abdominal Compartment Syndrome	40%
4	Arthrogryposis	38.5%
5	Fibromyalgia	29.1%
6	Polymyalgia Rheumatica	29.1%
7	Myofascial Pain Syndromes	28.4%
8	Rhabdomyolysis	28.4%
9	Osteoarthropathy, Secondary Hypertrophic	27.3%
10	Temporomandibular Joint Disorders	25.4%
11	Temporomandibular Joint Dysfunction Syndrome	25.3%
12	Tendinitis	23.9%
13	Tendinopathy	23.9%
14	Myositis	23.6%
15	Isaacs syndrome	23.6%
16	Myotonic Disorders	23.6%
17	Metatarsalgia	23.2%
18	Periarthritis	22.2%
19	Gout	21.5%
20	Dupuytren Contracture	21%
21	Bone Diseases	20.8%
22	Fasciitis	20.8%
23	Foot Deformities	20.8%
24	Contracture	20.5%
25	Fasciitis, Plantar	20.5%
26	Medial Tibial Stress Syndrome	20.4%
27	Osteoarthritis, Spine	20.3%
28	Arthritis	20.3%
29	Bursitis	20.3%
30	Joint Instability	20.3%
31	Synovitis	20.3%
32	Joint laxity	20.3%
33	Polyarthritis	20.3%
34	Frozen shoulder	20.3%
35	Patellofemoral Pain Syndrome	20.3%
36	Mitochondrial Myopathies	20.2%
37	Muscle Cramp	20.1%
38	Eosinophilia-Myalgia Syndrome	20.1%
39	Muscle Rigidity	20%
40	Muscle Spasticity	20%
41	Cogwheel Rigidity	20%
42	Nuchal Rigidity	20%
43	Fibrodysplasia Ossificans Progressiva	18.7%
44	Myoglobinuria	18.7%
45	Myositis Ossificans	18.7%
46	Tenosynovitis	18.7%
47	Ankylosing spondylitis	18.4%
48	Chronic Fatigue Syndrome	18.3%
49	Rheumatic Fever	18.2%
50	Pectus carinatum	18%
51	Jaw Diseases	17.9%
52	Muscle Weakness	17.7%
53	Musculoskeletal Pain	17.6%
54	Familial Periodic Paralysis	17.5%
55	Osteochondritis	17.5%
56	Cartilage Diseases	17.4%
57	Foot Diseases	17.4%
58	Rheumatism	17.4%
59	Chondromalacia	17.4%
60	Hemarthrosis	16.9%
61	Ischemic contracture	16.7%
62	Rheumatoid Arthritis	16.1%
63	Juvenile arthritis	16.1%
64	Arthritis, Psoriatic	16.1%
65	Enthesopathy	15.6%
66	Polymyositis	15.5%
67	Myalgia	15.5%
68	Arthritis, Gouty	15.3%
69	Platybasia	14.9%
70	Osteoarthritis, Knee	14.9%
71	Myotonic Dystrophy	14.7%
72	Pectus excavatum	14.4%
73	Arthritis, Reactive	14%
74	Arthropathy	13.9%
75	Compartment syndromes	13.6%
76	Myocardial Ischemia	13.6%
77	Muscular Dystrophy	13.4%
78	Orbital Myositis	13.4%
79	Aortic Aneurysm	13.3%
80	Aortitis	13.3%
81	Leriche Syndrome	13.3%
82	Periphlebitis	13.3%
83	Phlebitis	13.3%
84	Thromboangiitis Obliterans	13.3%
85	Sacroiliitis	13.3%
86	Pyomyositis	13.3%
87	Rheumatoid Vasculitis	13.2%
88	Talipes	12.9%
89	Klippel-Feil Syndrome	12.9%
90	Synostosis	12.9%
91	Rheumatoid Nodule	12.7%
92	Nail-Patella Syndrome	12.7%
93	Arthralgia	12.4%
94	Polyarthralgia	12.4%
95	Spondylarthropathies	12.3%
96	Retinal Vein Occlusion	12.3%
97	Aneurysm	12.2%
98	Angiomatosis	12.2%
99	Aortic Diseases	12.2%
100	Arterial Occlusive Diseases	12.2%
101	Bone Diseases, Developmental	12.2%
102	Hyperemia	12.2%
103	Hyperostosis	12.2%
104	Hypotension	12.2%
105	Osteitis	12.2%
106	Osteitis Deformans	12.2%
107	Osteochondrosis	12.2%
108	Spinal Diseases	12.2%
109	Superior Vena Cava Syndrome	12.2%
110	Telangiectasis	12.2%
111	Vasculitis	12.2%
112	Venous Insufficiency	12.2%
113	Peripheral Vascular Diseases	12.2%
114	Embolism and Thrombosis	12.2%
115	Angiodysplasia	12.2%
116	Capillary Leak Syndrome	12.2%
117	Prehypertension	12.2%
118	Thrombophlebitis	11.9%
119	Myocardial Reperfusion Injury	11.8%
120	Myotonia Congenita	11.6%
121	Postphlebitic Syndrome	11.6%
122	Craniosynostosis	11.5%
123	Syndactyly	11.5%
124	Brachycephaly	11.5%
125	Hypokalemic periodic paralysis	11.5%
126	Gigantism	11.4%
127	Spinal Neoplasms	11.4%
128	Spondylitis	11.4%
129	Malignant Atrophic Papulosis	11.4%
130	Acrocephalosyndactylia	11.4%
131	Shwartzman Phenomenon	11.4%
132	Coronary Aneurysm	11.3%
133	Arthritis, Infectious	11.2%
134	Aortic Rupture	11.2%
135	Felty Syndrome	11.2%
136	Arthritis, Experimental	11.1%
137	Bone Diseases, Endocrine	10.5%
138	Vascular System Injuries	10.5%
139	Carotid Artery Thrombosis	10.4%
140	Moyamoya Disease	10.3%
141	Blue Toe Syndrome	10.3%
142	Mitochondrial Encephalomyopathies	10.3%
143	Bone Diseases, Infectious	10.2%
144	Bone neoplasms	10.2%
145	Hepatic Veno-Occlusive Disease	10.2%
146	Maxillary Diseases	10.2%
147	Osteopenia	10.2%
148	Peliosis Hepatis	10.2%
149	Varicocele	10.2%
150	Bone Resorption	10.1%
151	Cerebrovascular Disorders	10.1%
152	Diabetic Angiopathies	10.1%
153	Reperfusion Injury	10.1%
154	Splenic Infarction	10.1%
155	Tietze's Syndrome	10.1%
156	Limb Deformities, Congenital	10.1%
157	Cerebrovascular Insufficiency	10.1%
158	Vascular Neoplasms	10.1%
159	Craniofacial Abnormalities	10.1%
160	Aseptic Necrosis of Bone	10.1%
161	Spinal Cord Vascular Diseases	10.1%
162	Vasoplegia	10.1%
163	Congenital clubfoot	10.1%
164	Vertical Talus	10.1%
165	Hemorrhoids	10.1%
166	Thoracic Outlet Syndrome	10.1%
167	Intracranial Embolism and Thrombosis	9.9%
168	Craniofacial Dysostosis	9.9%
169	Aortic Aneurysm, Abdominal	9.9%
170	Aortic Aneurysm, Thoracic	9.9%
171	Carotid Stenosis	9.9%
172	Intracranial Aneurysm	9.9%
173	Welander Distal Myopathy	9.9%
174	Coronary Thrombosis	9.9%
175	Coronary Artery Disease	9.9%
176	Arteriovenous fistula	9.9%
177	Hip Dislocation	9.7%
178	Shoulder Dislocation	9.7%
179	Hip Dysplasia	9.7%
180	Jaw Abnormalities	9%
181	Poland Syndrome	8.9%
182	Vasculitis, Central Nervous System	8.9%
183	Sicca Syndrome	8.9%
184	Hand-Arm Vibration Syndrome	8.9%
185	Sjogren's Syndrome	8.9%
186	Coronary heart disease	8.9%
187	Myocardial Infarction	8.9%
188	Acute Coronary Syndrome	8.9%
189	Dermatomyositis	8.8%
190	Optic Neuropathy, Ischemic	8.7%
191	Anterior Ischemic Optic Neuropathy	8.7%
192	Mesenteric vascular insufficiency	8.7%
193	Muscular Dystrophy, Duchenne	8.7%
194	Prognathism	8.6%
195	Gastroschisis	8.6%
196	Angioedema	8.6%
197	Colitis, Ischemic	8.6%
198	Polyarteritis Nodosa	8.5%
199	Takayasu Arteritis	8.5%
200	Discitis	8.5%
201	Intracranial Arteriosclerosis	8.4%
202	Cerebral Atherosclerosis	8.4%
203	Cerebral Arteriosclerosis	8.4%
204	Shoulder Pain	8.2%
205	Giant Cell Arteritis	8%
206	Temporal Arteritis	8%
207	Ainhum	8%
208	Aneurysm, Dissecting	8%
209	Arteriosclerosis	8%
210	Arteritis	8%
211	Bunion	8%
212	Dysostoses	8%
213	Embolism	8%
214	Erythromelalgia	8%
215	Fibromuscular Dysplasia	8%
216	Malignant Hypertension	8%
217	Raynaud Disease	8%
218	Spinal Stenosis	8%
219	Spondylosis	8%
220	Thromboembolism	8%
221	Thrombosis	8%
222	Essential Hypertension	8%
223	Intervertebral Disc Degeneration	8%
224	Aneurysm, Ruptured	8%
225	Iliac Aneurysm	8%
226	Pulmonary artery stenosis	8%
227	White Coat Hypertension	8%
228	Systemic Vasculitis	8%
229	Embolus	8%
230	Congenital Hypothyroidism	7.8%
231	Cerebral Thrombosis	7.7%
232	Intracranial Embolism	7.7%
233	Intracranial Thrombosis	7.7%
234	Kounis Syndrome	7.7%
235	Giant Cell Epulis	7.6%
236	May-Thurner Syndrome	7.6%
237	Angina Pectoris	7.6%
238	MELAS Syndrome	7.5%
239	Scimitar Syndrome	7.5%
240	Tuberculosis, Spinal	7.4%
241	Brain Infarction	7.3%
242	Lemierre Syndrome	7.2%
243	Embolism, Amniotic Fluid	7.2%
244	Antley-Bixler Syndrome Phenotype	7.1%
245	Subarachnoid Hemorrhage, Traumatic	7.1%
246	Carotid Artery, Internal, Dissection	7.1%
247	Heart Diseases	6.9%
248	CREST Syndrome	6.9%
249	Laryngomalacia	6.8%
250	Infarction, Middle Cerebral Artery	6.8%
251	Infarction, Anterior Cerebral Artery	6.8%
252	Infarction, Posterior Cerebral Artery	6.8%
253	Mandibulofacial Dysostosis	6.8%
254	Multiple Epiphyseal Dysplasia	6.7%
255	Osteochondrodysplasias	6.7%
256	Retinal Artery Occlusion	6.7%
257	Retinal Vasculitis	6.7%
258	Hypertensive Retinopathy	6.7%
259	Noonan Syndrome	6.7%
260	Osteomyelitis	6.7%
261	Osteoporosis	6.7%
262	Periostitis	6.7%
263	Vasculitis, Leukocytoclastic, Cutaneous	6.7%
264	Bone Demineralization, Pathologic	6.7%
265	Gastric Antral Vascular Ectasia	6.7%
266	Post-Traumatic Osteoporosis	6.7%
267	Eosinophilic Granuloma	6.6%
268	Alveolar Bone Loss	6.6%
269	Amelia	6.6%
270	Arachnodactyly	6.6%
271	Carotid Artery Diseases	6.6%
272	Brain Ischemia	6.6%
273	Ectromelia	6.6%
274	Femur Head Necrosis	6.6%
275	Hemimelia	6.6%
276	Hypotension, Orthostatic	6.6%
277	Phocomelia	6.6%
278	Sirenomelia	6.6%
279	Cerebrovascular accident	6.6%
280	Varicose Ulcer	6.6%
281	Polydactyly	6.6%
282	Brachydactyly	6.6%
283	Plagiocephaly	6.6%
284	Lower Extremity Deformities, Congenital	6.6%
285	Upper Extremity Deformities, Congenital	6.6%
286	Vasospasm, Intracranial	6.6%
287	Spinal Cord Ischemia	6.6%
288	Intracranial Arterial Diseases	6.6%
289	Primary Graft Dysfunction	6.6%
290	Post-Exercise Hypotension	6.6%
291	Osteolysis	6.6%
292	Sinus Thrombosis, Intracranial	6.6%
293	Goldenhar Syndrome	6.6%
294	Coronary Occlusion	6.6%
295	Microvascular Angina	6.6%
296	Coronary Stenosis	6.6%
297	ST segment elevation myocardial infarction	6.6%
298	Vertebral Artery Dissection	6.6%
299	Palatal Neoplasms	6.4%
300	Micrognathism	6.4%
301	Pierre Robin Syndrome	6.4%
302	Rubinstein-Taybi Syndrome	6.3%
303	Marfan Syndrome	6.1%
304	Cavernous Sinus Thrombosis	6.1%
305	Sagittal Sinus Thrombosis	6.1%
306	Cerebral Infarction	6.1%
307	Brain Stem Infarctions	6.1%
308	Arteriosclerosis Obliterans	6%
309	Atherosclerosis	6%
310	Chondrodysplasia Punctata	6%
311	Air Embolism	6%
312	Enchondromatosis	6%
313	Endarteritis	6%
314	Lordosis	6%
315	Osteosclerosis	6%
316	Spondylolysis	6%
317	Venous Thrombosis	6%
318	Deep Vein Thrombosis	6%
319	Venous Thromboembolism	6%
320	kyphosis	6%
321	Kashin-Beck Disease	6%
322	Dwarfism	5.9%
323	Carotid Artery Injuries	5.9%
324	Myopathy	5.8%
325	Pregnancy Complications, Cardiovascular	5.8%
326	Cardiovascular Abnormalities	5.8%
327	Retrognathia	5.8%
328	Kearns-Sayre syndrome	5.8%
329	Mesenteric Vascular Occlusion	5.8%
330	Mucocutaneous Lymph Node Syndrome	5.8%
331	Diabetic Retinopathy	5.7%
332	Sturge-Weber Syndrome	5.7%
333	Livedo Reticularis	5.7%
334	Renal hypertension	5.7%
335	Renal Artery Obstruction	5.7%
336	Renal Artery Stenosis	5.7%
337	Acromegaly	5.7%
338	Joint Tuberculosis	5.7%
339	Tuberculosis, Osteoarticular	5.7%
340	Bone Tuberculosis	5.7%
341	Hemangioma, Cavernous	5.7%
342	Shock, Cardiogenic	5.7%
343	Basal Ganglia Cerebrovascular Disease	5.7%
344	Vascular Headaches	5.6%
345	Scurvy	5.6%
346	Angina, Unstable	5.6%
347	Coronary Restenosis	5.5%
348	Lateral Medullary Syndrome	5.5%
349	Basal Ganglia Hemorrhage	5.3%
350	Basal Cell Nevus Syndrome	5.3%
351	Intermittent Claudication	5%
352	Pulmonary Embolism	5%
353	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5%
354	Maxillofacial Abnormalities	5%
355	Angioedemas, Hereditary	5%
356	Tricuspid Atresia	5%
357	Arrhythmogenic Right Ventricular Dysplasia	5%
358	No-Reflow Phenomenon	5%
359	Rickets	5%
360	Cryoglobulinemia	5%
361	Leukomalacia, Periventricular	5%
362	Bronchomalacia	5%
363	Tracheomalacia	5%
364	Melorheostosis	5%
365	Osteopetrosis	5%
366	Spondylolisthesis	5%
367	Osteoporosis, Postmenopausal	4.9%
368	Cerebral Arterial Diseases	4.9%
369	Vertebrobasilar Insufficiency	4.9%
370	Anterior Spinal Artery Syndrome	4.9%
371	Basilar Artery Stenosis	4.9%
372	Vertebral Artery Stenosis	4.9%
373	Intracranial Hemorrhage, Hypertensive	4.9%
374	Transient Cerebral Ischemia	4.9%
375	Microcephaly	4.9%
376	Diabetic Foot	4.9%
377	Macrocephaly	4.9%
378	Cleft Palate	4.9%
379	Angina Pectoris, Variant	4.7%
380	Putaminal Hemorrhage	4.6%
381	Aortic Valve Stenosis	4.4%
382	Cardiomyopathy, Dilated	4.4%
383	Pulmonary Valve Stenosis	4.4%
384	Dementia, Vascular	4.4%
385	Pseudohypoparathyroidism	4.4%
386	Shy-Drager Syndrome	4.4%
387	Purpura, Hyperglobulinemic	4.4%
388	Osteogenesis Imperfecta	4.3%
389	Bacterial Endocarditis	4.2%
390	Mastoiditis	4.2%
391	Petrositis	4.2%
392	Hypertension, Renovascular	4.2%
393	Subarachnoid Hemorrhage	4.2%
394	Hypoxia-Ischemia, Brain	4.2%
395	Cerebral Hemorrhage	4.2%
396	Hereditary Angioedema Type III	4.2%
397	Hereditary Angioedema Types I and II	4.2%
398	Hepatic Vein Thrombosis	4.2%
399	Budd-Chiari Syndrome	4.2%
400	Pulmonary Infarction	4.1%
401	Subclavian Steal Syndrome	4.1%
402	Cardiac Tamponade	4.1%
403	Endocarditis	4.1%
404	Cardiac Arrest	4.1%
405	Heart failure	4.1%
406	Pericardial effusion	4.1%
407	Pericarditis	4.1%
408	Pneumopericardium	4.1%
409	Cor pulmonale	4.1%
410	Ventricular Outflow Obstruction	4.1%
411	Ventricular Dysfunction	4.1%
412	Cardiomyopathies	4.1%
413	Pleuropericarditis	4.1%
414	Behcet Syndrome	4%
415	Waldenstrom Macroglobulinemia	4%
416	Multiple Myeloma	4%
417	Lupus Vasculitis, Central Nervous System	3.9%
418	Heart Block	3.8%
419	Tachycardia	3.8%
420	Tachyarrhythmia	3.8%
421	Aortic coarctation	3.8%
422	Cor Triatriatum	3.8%
423	Coronary Vessel Anomalies	3.8%
424	Patent ductus arteriosus	3.8%
425	Ebstein Anomaly	3.8%
426	Heart Septal Defects	3.8%
427	Tetralogy of Fallot	3.8%
428	Transposition of Great Vessels	3.8%
429	Hypoplastic Left Heart Syndrome	3.8%
430	Pituitary Apoplexy	3.7%
431	Osteomalacia	3.7%
432	Porencephaly	3.7%
433	Ataxia Telangiectasia	3.7%
434	Pseudoxanthoma Elasticum	3.6%
435	Holoprosencephaly	3.6%
436	Hypertrophic Cardiomyopathy	3.6%
437	Hypertrophic obstructive cardiomyopathy	3.6%
438	Granulomatosis with polyangiitis	3.5%
439	Cerebral Amyloid Angiopathy	3.5%
440	Cardiac Output, High	3.4%
441	Myocardial Stunning	3.4%
442	Low Cardiac Output Syndrome	3.4%
443	Cardiomegaly	3.4%
444	Postpericardiotomy Syndrome	3.4%
445	Cardiac Hypertrophy	3.4%
446	Rheumatic Heart Disease	3.3%
447	Dextrocardia	3.3%
448	Long QT Syndrome	3.3%
449	Supravalvular aortic stenosis	3.3%
450	Lown-Ganong-Levine Syndrome	3.3%
451	Sick Sinus Syndrome	3.3%
452	Cockayne Syndrome	3%
453	Adams-Stokes Syndrome	2.8%
454	Atrioventricular Block	2.8%
455	Bundle-Branch Block	2.8%
456	Atrial Premature Complexes	2.8%
457	Sinoatrial Block	2.8%
458	Tachycardia, Paroxysmal	2.8%
459	Supraventricular tachycardia	2.8%
460	Tachycardia, Ventricular	2.8%
461	Wolff-Parkinson-White Syndrome	2.8%
462	Tachycardia, Reciprocating	2.8%
463	Aortopulmonary Septal Defect	2.8%
464	Double Outlet Right Ventricle	2.8%
465	Endocardial Cushion Defects	2.8%
466	Myocardial bridging	2.8%
467	Aorticopulmonary Septal Defect	2.8%
468	Nose Neoplasms	2.8%
469	Radicular Cyst	2.7%
470	Renal Osteodystrophy	2.7%
471	Renal rickets	2.7%
472	Aortic Valve Insufficiency	2.7%
473	Restrictive cardiomyopathy	2.7%
474	Endocardial Fibroelastosis	2.7%
475	Heart Rupture, Post-Infarction	2.7%
476	Mitral Valve Insufficiency	2.7%
477	Mitral Valve Stenosis	2.7%
478	Myocarditis	2.7%
479	Pericarditis, Constrictive	2.7%
480	Pulmonary Valve Insufficiency	2.7%
481	Tricuspid Valve Insufficiency	2.7%
482	Tricuspid Valve Stenosis	2.7%
483	Ventricular Dysfunction, Left	2.7%
484	Right Ventricular Dysfunction	2.7%
485	Endomyocardial Fibrosis	2.7%
486	Carditis	2.7%
487	Heart Failure, Systolic	2.7%
488	Heart Failure, Diastolic	2.7%
489	Subacute Bacterial Endocarditis	2.6%
490	Carcinoid Heart Disease	2.5%
491	Romano-Ward Syndrome	2.5%
492	Hematoma, Subdural	2.4%
493	Hematoma, Epidural, Cranial	2.4%
494	Tachycardia, Atrioventricular Nodal Reentry	2.3%
495	Tachycardia, Ectopic Atrial	2.3%
496	Tachycardia, Ectopic Junctional	2.3%
497	Sinus Tachycardia	2.3%
498	Torsades de Pointes	2.3%
499	Accelerated Idioventricular Rhythm	2.3%
500	Truncus Arteriosus, Persistent	2.3%
501	Sinus Arrhythmia	2.2%
502	Atrial Fibrillation	2.2%
503	Atrial Flutter	2.2%
504	Edema, Cardiac	2.2%
505	Ventricular Fibrillation	2.2%
506	Ventricular Flutter	2.2%
507	Parasystole	2.2%
508	Paroxysmal atrial fibrillation	2.2%
509	Bradycardia	2.2%
510	Diabetic Cardiomyopathies	2.2%
511	Brain Hemorrhage, Traumatic	2.2%
512	Cardiomyopathy, Alcoholic	2.2%
513	Ectopia Cordis	2.2%
514	Sudden Cardiac Death	2.2%
515	Left Ventricular Hypertrophy	2.2%
516	Right Ventricular Hypertrophy	2.2%
517	Single umbilical artery	2.2%
518	Chagas Cardiomyopathy	2.2%
519	Hematoma, Subdural, Intracranial	2.2%
520	Hematoma, Subdural, Chronic	2.2%
521	Hematoma, Subdural, Acute	2.2%
522	Aortic Valve Prolapse	2%
523	Tricuspid Valve Prolapse	2%
524	Takotsubo Cardiomyopathy	2%
525	Dyspnea, Paroxysmal	1.9%
526	Fabry Disease	1.8%
527	Dural Arteriovenous Fistula	1.7%
528	Sinus Arrest, Cardiac	1.6%
529	Turner Syndrome	1.5%
530	Familial Hypophosphatemic Rickets	1.5%
531	Kartagener Syndrome	1.3%
532	Williams Syndrome	1%

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