MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Subclavian Steal Syndrome

(UMLS:C0038531)

Definition:: A clinically significant reduction in blood supply to the BRAIN STEM and CEREBELLUM (i.e., VERTEBROBASILAR INSUFFICIENCY) resulting from reversal of blood flow through the VERTEBRAL ARTERY from occlusion or stenosis of the proximal subclavian or brachiocephalic artery. Common symptoms include VERTIGO; SYNCOPE; and INTERMITTENT CLAUDICATION of the involved upper extremity. Subclavian steal may also occur in asymptomatic individuals. (From J Cardiovasc Surg 1994;35(1):11-4; Acta Neurol Scand 1994;90(3):174-8)
UMLS ID:: C0038531
MeSH ID:: D013349

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.150.956.700

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.092.956.700

Synonym(s)

Subclavian Steal Syndrome

BRACHIAL-BASILAR INSUFFICIENCY SYNDROME

SUBCLAVIAN ARTERY STENOSIS

Subclavian artery stenosis

Subclavian steal syndrome

artery stenosis subclavian

steal subclavian syndrome

stenosis of subclavian artery

subclavian artery stenosis

10.

subclavian steal syndrome

11.

subclavian steal; syndrome

12.

syndrome; subclavian steal

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Dimethyl Fumarate	FAERS: 2	US FAERS
2	rofecoxib	FAERS: 2	US FAERS
3	Lenalidomide	FAERS: 1	US FAERS
4	apixaban	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Transient Cerebral Ischemia	36.4%
2	Brain Infarction	35.9%
3	Hypoxia-Ischemia, Brain	34.8%
4	Carotid Artery Diseases	29.2%
5	Cerebrovascular accident	29.2%
6	Vasospasm, Intracranial	29.2%
7	Intracranial Arterial Diseases	29.2%
8	Basal Ganglia Cerebrovascular Disease	29%
9	Vascular Headaches	26.6%
10	Intracranial Embolism and Thrombosis	26.2%
11	Leukomalacia, Periventricular	24.3%
12	Cerebral Infarction	23.7%
13	Brain Stem Infarctions	23.7%
14	Vasculitis, Central Nervous System	22.6%
15	Moyamoya Disease	20%
16	Dementia, Vascular	19.1%
17	Infarction, Middle Cerebral Artery	19%
18	Infarction, Anterior Cerebral Artery	19%
19	Infarction, Posterior Cerebral Artery	19%
20	Carotid Stenosis	18.8%
21	Intracranial Aneurysm	18.8%
22	Carotid Artery Thrombosis	18.7%
23	Carotid Artery Injuries	18.4%
24	Lateral Medullary Syndrome	17.7%
25	Cerebral Arterial Diseases	17.3%
26	Intracranial Hemorrhage, Hypertensive	17.3%
27	Akinetic Mutism	16.9%
28	Anoxic Encephalopathy	16.9%
29	Basal Ganglia Diseases	16.9%
30	Brain Damage, Chronic	16.9%
31	Cerebellar Diseases	16.9%
32	Encephalitis	16.9%
33	Encephalomalacia	16.9%
34	Epilepsy	16.9%
35	Hydrocephalus	16.9%
36	Congenital Hydrocephalus	16.9%
37	Hypothalamic Diseases	16.9%
38	Thalamic Diseases	16.9%
39	Intracranial Hypertension	16.9%
40	Aura	16.9%
41	Leukoencephalopathy	16.9%
42	Neuroaxonal Dystrophies	16.9%
43	Headache Disorders	16.9%
44	Intracranial Hypotension	16.9%
45	Brain Edema	16.9%
46	Brain Hypoxia	16.9%
47	Aqueductal Stenosis	16.9%
48	Intracranial Arteriosclerosis	16.7%
49	Cerebral Atherosclerosis	16.7%
50	Cerebral Arteriosclerosis	16.7%
51	Spinal Cord Vascular Diseases	16.7%
52	Basal Ganglia Hemorrhage	16.5%
53	Encephalomyelitis	16.1%
54	Cerebral Thrombosis	15.7%
55	Intracranial Embolism	15.7%
56	Intracranial Thrombosis	15.7%
57	Subdural Effusion	15.7%
58	Myocardial Ischemia	15.1%
59	Aneurysm	14.8%
60	Angiomatosis	14.8%
61	Aortic Diseases	14.8%
62	Arterial Occlusive Diseases	14.8%
63	Hyperemia	14.8%
64	Hypotension	14.8%
65	Superior Vena Cava Syndrome	14.8%
66	Telangiectasis	14.8%
67	Vasculitis	14.8%
68	Venous Insufficiency	14.8%
69	Peripheral Vascular Diseases	14.8%
70	Embolism and Thrombosis	14.8%
71	Angiodysplasia	14.8%
72	Capillary Leak Syndrome	14.8%
73	Prehypertension	14.8%
74	Pituitary Apoplexy	14.6%
75	Subarachnoid Hemorrhage, Traumatic	14.4%
76	Meningoencephalitis	14%
77	Meningitis	14%
78	Movement Disorders	14%
79	Pachymeningitis	14%
80	Spinal Cord Diseases	14%
81	Subarachnoid Hemorrhage	13.9%
82	Cerebral Hemorrhage	13.9%
83	Vertebral Artery Dissection	13.1%
84	Brain Diseases, Metabolic	13%
85	Dementia	13%
86	Parkinsonian Disorders	12.5%
87	Pneumocephalus	12.3%
88	Brain Abscess	12.3%
89	Carotid Artery, Internal, Dissection	12.3%
90	Aortic Aneurysm	12.2%
91	Aortitis	12.2%
92	Leriche Syndrome	12.2%
93	Periphlebitis	12.2%
94	Phlebitis	12.2%
95	Thromboangiitis Obliterans	12.2%
96	Multiple System Atrophy	12.1%
97	Thoracic Outlet Syndrome	12.1%
98	Dandy-Walker Syndrome	11.9%
99	Ocular Motility Disorders	11.9%
100	Cyclophoria	11.9%
101	Giant Cell Arteritis	11.8%
102	Temporal Arteritis	11.8%
103	Brain Injuries	11.7%
104	Vascular System Injuries	11.7%
105	Brain Neoplasms	11.7%
106	Putaminal Hemorrhage	11.4%
107	Compartment syndromes	11.3%
108	Hepatic Veno-Occlusive Disease	11.3%
109	Peliosis Hepatis	11.3%
110	Varicocele	11.3%
111	Diabetic Angiopathies	11.1%
112	Reperfusion Injury	11.1%
113	Splenic Infarction	11.1%
114	Vascular Neoplasms	11.1%
115	Vasoplegia	11.1%
116	Posterior Leukoencephalopathy Syndrome	11.1%
117	Posterior reversible encephalopathy syndrome	11.1%
118	Central Nervous System Infection	11.1%
119	Hemorrhoids	11%
120	Myelitis	11%
121	Retinal Vein Occlusion	10.9%
122	Hand-Arm Vibration Syndrome	10.8%
123	Lupus Vasculitis, Central Nervous System	10.8%
124	Marchiafava-Bignami Disease	10.6%
125	Sinus Thrombosis, Intracranial	10.6%
126	Optic Neuropathy, Ischemic	10.6%
127	Anterior Ischemic Optic Neuropathy	10.6%
128	Brain Death	10.5%
129	Lewy Body Disease	10.2%
130	Epilepsy, Post-Traumatic	10%
131	Meige Syndrome	10%
132	Cerebral Ventriculitis	10%
133	Malignant Atrophic Papulosis	9.8%
134	Heart Diseases	9.7%
135	Shwartzman Phenomenon	9.7%
136	Postphlebitic Syndrome	9.7%
137	Cranial nerve diseases	9.5%
138	Demyelinating Diseases	9.5%
139	Demyelination	9.5%
140	Neuromuscular Diseases	9.5%
141	Chronobiology Disorders	9.5%
142	Myocardial Reperfusion Injury	9.3%
143	Epidural Abscess	9.3%
144	Cerebral Palsy	9.3%
145	Epilepsies, Partial	9.3%
146	Epilepsy, Generalized	9.3%
147	Pseudotumor Cerebri	9.3%
148	Hypertensive Encephalopathy	9.3%
149	Simple Partial Seizures	9.3%
150	Epilepsy, Reflex	9.3%
151	Headache Disorders, Primary	9.3%
152	Headache Disorders, Secondary	9.3%
153	Medication overuse headache	9.3%
154	Amblyopia	9.3%
155	Shy-Drager Syndrome	9.2%
156	Cerebral Amyloid Angiopathy	9.2%
157	Brain Hemorrhage, Traumatic	9.1%
158	Prion Diseases	9.1%
159	Spinal Cord Ischemia	9.1%
160	Mesenteric vascular insufficiency	9%
161	Angioedema	8.8%
162	Colitis, Ischemic	8.8%
163	Coronary Aneurysm	8.7%
164	Parkinson Disease	8.6%
165	Neuroleptic Malignant Syndrome	8.5%
166	Myelinolysis, Central Pontine	8.5%
167	Stiff-Person Syndrome	8.5%
168	Myoclonic Epilepsy	8.3%
169	Epilepsy, Temporal Lobe	8.3%
170	Epilepsy, Rolandic	8.3%
171	Benign Rolandic Epilepsy	8.3%
172	Coronary heart disease	8.1%
173	Myocardial Infarction	8.1%
174	Acute Coronary Syndrome	8.1%
175	MELAS Syndrome	8.1%
176	Creutzfeldt-Jakob disease	8.1%
177	Aneurysm, Dissecting	8%
178	Arteriosclerosis	8%
179	Arteritis	8%
180	Embolism	8%
181	Erythromelalgia	8%
182	Fibromuscular Dysplasia	8%
183	Malignant Hypertension	8%
184	Raynaud Disease	8%
185	Thromboembolism	8%
186	Thrombosis	8%
187	Essential Hypertension	8%
188	Aneurysm, Ruptured	8%
189	Iliac Aneurysm	8%
190	Pulmonary artery stenosis	8%
191	White Coat Hypertension	8%
192	Systemic Vasculitis	8%
193	Embolus	8%
194	Cavernous Sinus Thrombosis	8%
195	Sagittal Sinus Thrombosis	8%
196	Dystonia Musculorum Deformans	8%
197	Huntington Disease	7.9%
198	Cerebellar Neoplasms	7.8%
199	Blue Toe Syndrome	7.8%
200	Sturge-Weber Syndrome	7.7%
201	Thrombophlebitis	7.7%
202	Amnesia, Transient Global	7.6%
203	Spinal Cord Injuries	7.6%
204	Trauma, Nervous System	7.4%
205	Pituitary Diseases	7.4%
206	Pregnancy Complications, Cardiovascular	7.4%
207	Cardiovascular Abnormalities	7.4%
208	Spinal Muscular Atrophy	7.3%
209	Progressive Muscular Atrophy	7.3%
210	Aortic Rupture	7.3%
211	Progressive supranuclear palsy	7.3%
212	Asterixis	7.3%
213	Ballismus	7.3%
214	Arteriovenous fistula	7.3%
215	Arachnoiditis	7.2%
216	Aseptic Meningitis	7.2%
217	Syringomyelia	7.2%
218	Essential Tremor	7.2%
219	Familial Tremor	7.2%
220	Pneumorrhachis	7.2%
221	Writer's Cramp	7.2%
222	Subacute Combined Degeneration	7.2%
223	Aortic Aneurysm, Abdominal	7.2%
224	Aortic Aneurysm, Thoracic	7.2%
225	Nervous System Neoplasms	7.2%
226	Neurologic Manifestations	7.2%
227	Neurotoxicity Syndromes	7.2%
228	Presenile dementia	7.1%
229	Senile dementia	7.1%
230	Motor Neuron Disease	7.1%
231	Hypotension, Orthostatic	7%
232	Kluver-Bucy Syndrome	7%
233	Post-Exercise Hypotension	7%
234	Limbic Encephalitis	6.8%
235	Meningitis, Bacterial	6.8%
236	Meningitis, Fungal	6.8%
237	Coronary Thrombosis	6.7%
238	Coronary Artery Disease	6.7%
239	Scimitar Syndrome	6.7%
240	Striatonigral Degeneration	6.7%
241	Kounis Syndrome	6.6%
242	May-Thurner Syndrome	6.5%
243	Angina Pectoris	6.5%
244	Brain Injuries, Diffuse	6.4%
245	Traumatic Brain Injury	6.4%
246	Cerebellar Ataxia	6.4%
247	Supratentorial Neoplasms	6.4%
248	Poliomyelitis	6.4%
249	Chronic Fatigue Syndrome	6.3%
250	Leukoencephalopathy, Progressive Multifocal	6.3%
251	Amyotrophic Lateral Sclerosis	6.3%
252	Hematoma, Subdural	6.3%
253	Hematoma, Epidural, Cranial	6.3%
254	Retinal Artery Occlusion	6.2%
255	Retinal Vasculitis	6.2%
256	Hypertensive Retinopathy	6.2%
257	Anterior Compartment Syndrome	6.1%
258	Vasculitis, Leukocytoclastic, Cutaneous	6.1%
259	Gastric Antral Vascular Ectasia	6.1%
260	Abdominal Compartment Syndrome	6.1%
261	Varicose Ulcer	6%
262	Primary Graft Dysfunction	6%
263	Persistent Vegetative State	6%
264	Paraneoplastic Cerebellar Degeneration	5.9%
265	Embolism, Amniotic Fluid	5.9%
266	Sleep Wake Disorders	5.8%
267	Spinal Cord Neoplasms	5.8%
268	Ataxia Telangiectasia	5.8%
269	Polyarteritis Nodosa	5.8%
270	Takayasu Arteritis	5.8%
271	Hepatolenticular Degeneration	5.8%
272	Reye Syndrome	5.7%
273	Hepatic Encephalopathy	5.6%
274	Restless Legs Syndrome	5.6%
275	Central Nervous System Fungal Infections	5.6%
276	Conus Medullaris Syndrome	5.6%
277	Post-Traumatic Headache	5.5%
278	Tension Headache	5.5%
279	Epilepsy, Complex Partial	5.5%
280	Migraine Disorders	5.5%
281	Abdominal Migraine	5.5%
282	Status Migrainosus	5.5%
283	Cervicogenic Headache	5.5%
284	Juvenile Myoclonic Epilepsy	5.5%
285	Myoclonic Epilepsies, Progressive	5.5%
286	Fabry Disease	5.5%
287	MPTP Poisoning	5.4%
288	Polyradiculoneuropathy	5.4%
289	Polyradiculoneuritis	5.4%
290	Anterior Spinal Artery Syndrome	5.4%
291	Autonomic Dysreflexia	5.4%
292	Complex Regional Pain Syndromes	5.4%
293	Ophthalmoplegic Migraine	5.3%
294	Toxoplasmosis, Cerebral	5.3%
295	Encephalomyelitis, Acute Disseminated	5.2%
296	Akathisia, Drug-Induced	5.2%
297	Leukoencephalitis, Acute Hemorrhagic	5.1%
298	Mesenteric Vascular Occlusion	5%
299	Mucocutaneous Lymph Node Syndrome	5%
300	Miller Fisher Syndrome	4.9%
301	Cardiac Tamponade	4.9%
302	Endocarditis	4.9%
303	Cardiac Arrest	4.9%
304	Heart failure	4.9%
305	Pericardial effusion	4.9%
306	Pericarditis	4.9%
307	Pneumopericardium	4.9%
308	Cor pulmonale	4.9%
309	Ventricular Outflow Obstruction	4.9%
310	Ventricular Dysfunction	4.9%
311	Cardiomyopathies	4.9%
312	Pleuropericarditis	4.9%
313	Diabetic Retinopathy	4.9%
314	Livedo Reticularis	4.9%
315	Renal hypertension	4.9%
316	Renal Artery Obstruction	4.9%
317	Renal Artery Stenosis	4.9%
318	Hemangioma, Cavernous	4.8%
319	CREST Syndrome	4.8%
320	Scurvy	4.8%
321	Coronary Occlusion	4.8%
322	Microvascular Angina	4.8%
323	Coronary Stenosis	4.8%
324	ST segment elevation myocardial infarction	4.8%
325	Arteriosclerosis Obliterans	4.8%
326	Atherosclerosis	4.8%
327	Air Embolism	4.8%
328	Endarteritis	4.8%
329	Venous Thrombosis	4.8%
330	Deep Vein Thrombosis	4.8%
331	Venous Thromboembolism	4.8%
332	Brain Diseases, Metabolic, Inborn	4.7%
333	Pituitary Adenoma	4.7%
334	Pituitary Neoplasms	4.7%
335	Friedreich Ataxia	4.7%
336	Dysautonomia	4.7%
337	Vagus Nerve Disorder	4.7%
338	Glossopharyngeal Neuralgia	4.7%
339	Abducens Nerve Diseases	4.7%
340	Heavy Metal Poisoning, Nervous System	4.7%
341	Neuromuscular Junction Diseases	4.7%
342	Tauopathies	4.7%
343	Trochlear Nerve Diseases	4.7%
344	Peripheral Nervous System Diseases	4.7%
345	Myelitis, Transverse	4.6%
346	Mitochondrial Encephalomyopathies	4.6%
347	Hematoma, Subdural, Intracranial	4.6%
348	Hematoma, Subdural, Chronic	4.6%
349	Hematoma, Subdural, Acute	4.6%
350	Opsoclonus-Myoclonus Syndrome	4.6%
351	Central Nervous System Bacterial Infections	4.5%
352	Peripheral Nerve Injuries	4.4%
353	Myasthenia Gravis	4.3%
354	Empty Sella Syndrome	4.3%
355	Hyperpituitarism	4.3%
356	Hypopituitarism	4.3%
357	Hypophysitis	4.3%
358	Canavan Disease	4.3%
359	Alexander Disease	4.3%
360	Dyskinesia, Drug-Induced	4.2%
361	Ischemic contracture	4.1%
362	Angioedemas, Hereditary	4.1%
363	Tricuspid Atresia	4.1%
364	Arrhythmogenic Right Ventricular Dysplasia	4.1%
365	Aortic Valve Stenosis	4.1%
366	Cardiomyopathy, Dilated	4.1%
367	Pulmonary Valve Stenosis	4.1%
368	Cryoglobulinemia	4%
369	Wernicke Encephalopathy	4%
370	AIDS Dementia Complex	4%
371	Auditory Perceptual Disorders	4%
372	Diabetic Foot	4%
373	Lafora Disease	4%
374	Unverricht-Lundborg Syndrome	4%
375	Scrapie	3.9%
376	Central Cord Syndrome	3.9%
377	Bacterial Endocarditis	3.9%
378	Chorea	3.9%
379	Shock, Cardiogenic	3.9%
380	Angina, Unstable	3.8%
381	Diffuse Axonal Injury	3.8%
382	Brain Stem Neoplasms	3.8%
383	Cardiac Output, High	3.8%
384	Myocardial Stunning	3.8%
385	Low Cardiac Output Syndrome	3.8%
386	Tuberculosis, Meningeal	3.7%
387	Cardiomegaly	3.7%
388	Postpericardiotomy Syndrome	3.7%
389	Cardiac Hypertrophy	3.7%
390	Sleep Disorders, Circadian Rhythm	3.7%
391	Dural Arteriovenous Fistula	3.7%
392	Myopathy	3.7%
393	Optic Neuropathy	3.7%
394	Cluster Headache	3.7%
395	Migraine with Aura	3.7%
396	Familial Hemiplegic Migraine	3.7%
397	Chronic Paroxysmal Hemicrania	3.7%
398	SUNCT Syndrome	3.7%
399	Paroxysmal Hemicrania	3.7%
400	Intermittent Claudication	3.7%
401	Pulmonary Embolism	3.7%
402	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.7%
403	Rheumatic Heart Disease	3.7%
404	Progressive bulbar palsy	3.7%
405	Bulbar palsy	3.7%
406	No-Reflow Phenomenon	3.6%
407	Kernicterus	3.6%
408	Lambert-Eaton Myasthenic Syndrome	3.6%
409	Botulism	3.6%
410	Central Nervous System Cysts	3.6%
411	Facial Nerve Diseases	3.6%
412	Craniocerebral Trauma	3.6%
413	Parasomnia	3.6%
414	Dyssomnias	3.6%
415	Vestibulocochlear Nerve Diseases	3.5%
416	Decerebrate State	3.5%
417	Hemiparesis	3.5%
418	Hydranencephaly	3.5%
419	Meningism	3.5%
420	Neural Tube Defects	3.5%
421	Paresis	3.5%
422	Seizures	3.5%
423	Sensation Disorders	3.5%
424	Tethered Cord Syndrome	3.5%
425	Central Nervous System Neoplasms	3.5%
426	Complex partial seizures	3.5%
427	Iniencephaly	3.5%
428	Craniorachischisis	3.5%
429	Exencephaly	3.5%
430	Monoparesis	3.5%
431	Septo-Optic Dysplasia	3.5%
432	Cortical Dysplasia	3.5%
433	Neurogenic Inflammation	3.5%
434	Gait Disorders, Neurologic	3.5%
435	Neuromuscular Manifestations	3.5%
436	Malformations of Cortical Development	3.5%
437	Sweating, Gustatory	3.5%
438	Auriculotemporal Syndrome	3.5%
439	Guillain-Barre Syndrome	3.5%
440	Frontotemporal dementia	3.5%
441	Purpura, Hyperglobulinemic	3.5%
442	Lemierre Syndrome	3.4%
443	Heart Block	3.3%
444	Tachycardia	3.3%
445	Tachyarrhythmia	3.3%
446	Aortic coarctation	3.2%
447	Cor Triatriatum	3.2%
448	Coronary Vessel Anomalies	3.2%
449	Patent ductus arteriosus	3.2%
450	Ebstein Anomaly	3.2%
451	Heart Septal Defects	3.2%
452	Tetralogy of Fallot	3.2%
453	Transposition of Great Vessels	3.2%
454	Hypoplastic Left Heart Syndrome	3.2%
455	Meningitis, Cryptococcal	3.2%
456	Meningitis, Listeria	3.2%
457	Brain Contusion	3.2%
458	Torticollis	3.2%
459	Meningitis, Haemophilus	3.2%
460	Meningitis, Pneumococcal	3.2%
461	Coronary Restenosis	3.2%
462	Olfactory Nerve Injuries	3.1%
463	Behcet Syndrome	3.1%
464	Causalgia	3.1%
465	Waldenstrom Macroglobulinemia	3.1%
466	Multiple Myeloma	3.1%
467	Adrenoleukodystrophy	3%
468	Horner Syndrome	3%
469	Tuberculosis, Central Nervous System	3%
470	Pupil Disorders	2.9%
471	Neurobehavioral Manifestations	2.9%
472	Multiple Sclerosis	2.9%
473	Brain Concussion	2.9%
474	Subacute Sclerosing Panencephalitis	2.9%
475	Hypertension, Renovascular	2.9%
476	Hereditary Angioedema Type III	2.9%
477	Hereditary Angioedema Types I and II	2.9%
478	Paraneoplastic Encephalomyelitis	2.8%
479	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.8%
480	Reflex Sympathetic Dystrophy	2.8%
481	Nocturnal Myoclonus Syndrome	2.8%
482	Uveomeningoencephalitic Syndrome	2.8%
483	Hypertrophic Cardiomyopathy	2.8%
484	Hypertrophic obstructive cardiomyopathy	2.8%
485	Hyperprolactinemia	2.8%
486	Vertigo	2.8%
487	Alcohol-Induced Disorders, Nervous System	2.8%
488	Pick Disease of the Brain	2.8%
489	Pseudoxanthoma Elasticum	2.8%
490	Dextrocardia	2.7%
491	Long QT Syndrome	2.7%
492	Aortic Valve Insufficiency	2.7%
493	Restrictive cardiomyopathy	2.7%
494	Endocardial Fibroelastosis	2.7%
495	Heart Rupture, Post-Infarction	2.7%
496	Mitral Valve Insufficiency	2.7%
497	Mitral Valve Stenosis	2.7%
498	Myocarditis	2.7%
499	Pericarditis, Constrictive	2.7%
500	Pulmonary Valve Insufficiency	2.7%
501	Tricuspid Valve Insufficiency	2.7%
502	Tricuspid Valve Stenosis	2.7%
503	Ventricular Dysfunction, Left	2.7%
504	Right Ventricular Dysfunction	2.7%
505	Endomyocardial Fibrosis	2.7%
506	Carditis	2.7%
507	Heart Failure, Systolic	2.7%
508	Heart Failure, Diastolic	2.7%
509	Neuromyelitis Optica	2.7%
510	Facial Nerve Injuries	2.7%
511	Jet Lag Syndrome	2.6%
512	Angina Pectoris, Variant	2.5%
513	Choroid Plexus Papilloma	2.5%
514	Ophthalmoplegia	2.5%
515	External Ophthalmoplegia	2.5%
516	Hepatic Vein Thrombosis	2.4%
517	Budd-Chiari Syndrome	2.4%
518	Neuroaspergillosis	2.4%
519	Neuritis	2.4%
520	Polyneuritis	2.4%
521	Radiculitis	2.4%
522	Polyneuropathy	2.4%
523	Mononeuritis	2.4%
524	Mononeuropathies	2.4%
525	Brachial Plexus Neuropathies	2.4%
526	Radiculopathy	2.4%
527	Mononeuropathy Multiplex	2.4%
528	Nerve Root Compression	2.4%
529	Carcinoid Heart Disease	2.4%
530	Pulmonary Infarction	2.4%
531	Alice in Wonderland Syndrome	2.4%
532	Voice Disorders	2.4%
533	Voice Disturbance	2.4%
534	Supravalvular aortic stenosis	2.4%
535	Lown-Ganong-Levine Syndrome	2.4%
536	Tuberous Sclerosis	2.4%
537	Refsum Disease	2.4%
538	Smith-Magenis syndrome	2.3%
539	Myasthenia Gravis, Autoimmune, Experimental	2.3%
540	Acromegaly	2.3%
541	Acrodynia	2.2%
542	Tardive Dyskinesia	2.2%
543	Vocal Cord Paralysis	2.1%
544	Pseudorabies	2.1%
545	Galactosemias	2.1%
546	Urea Cycle Disorders, Inborn	2.1%
547	Tyrosinemias	2.1%
548	Rheumatoid Vasculitis	2.1%
549	Sick Sinus Syndrome	2.1%
550	Noonan Syndrome	2.1%
551	Sinus Arrhythmia	2%
552	Atrial Fibrillation	2%
553	Atrial Flutter	2%
554	Edema, Cardiac	2%
555	Ventricular Fibrillation	2%
556	Ventricular Flutter	2%
557	Parasystole	2%
558	Paroxysmal atrial fibrillation	2%
559	Bradycardia	2%
560	Diabetic Cardiomyopathies	2%
561	Cardiomyopathy, Alcoholic	2%
562	Ectopia Cordis	2%
563	Sudden Cardiac Death	2%
564	Left Ventricular Hypertrophy	2%
565	Right Ventricular Hypertrophy	2%
566	Single umbilical artery	2%
567	Chagas Cardiomyopathy	2%
568	Neurosyphilis	2%
569	Brachial Plexus Neuritis	2%
570	Neuralgic Amyotrophy	2%
571	Reflex, Abnormal	2%
572	Hyporeflexia	2%
573	Hyperreflexia	2%
574	Charcot-Marie-Tooth Disease	2%
575	Granulomatosis with polyangiitis	1.9%
576	Adams-Stokes Syndrome	1.9%
577	Atrioventricular Block	1.9%
578	Bundle-Branch Block	1.9%
579	Atrial Premature Complexes	1.9%
580	Sinoatrial Block	1.9%
581	Tachycardia, Paroxysmal	1.9%
582	Supraventricular tachycardia	1.9%
583	Tachycardia, Ventricular	1.9%
584	Wolff-Parkinson-White Syndrome	1.9%
585	Tachycardia, Reciprocating	1.9%
586	Aortopulmonary Septal Defect	1.9%
587	Double Outlet Right Ventricle	1.9%
588	Endocardial Cushion Defects	1.9%
589	Myocardial bridging	1.9%
590	Aorticopulmonary Septal Defect	1.9%
591	Myotonia Congenita	1.9%
592	Homocystinuria	1.9%
593	Cerebrospinal Fluid Otorrhea	1.9%
594	Cerebrospinal Fluid Rhinorrhea	1.9%
595	Neuritis, Autoimmune, Experimental	1.9%
596	Gait Ataxia	1.9%
597	Leigh Disease	1.9%
598	Myositis	1.9%
599	Optic Atrophy	1.9%
600	Optic Neuritis	1.9%
601	Papilledema	1.9%
602	Strabismus	1.9%
603	Tolosa-Hunt Syndrome	1.9%
604	Isaacs syndrome	1.9%
605	Arsenic Poisoning	1.9%
606	Myotonic Disorders	1.9%
607	Myasthenic Syndromes, Congenital	1.9%
608	Marfan Syndrome	1.9%
609	Subacute Bacterial Endocarditis	1.8%
610	Diabetic Neuropathies	1.8%
611	Facial Injuries	1.8%
612	Facial Neuralgia	1.8%
613	Diabetic Amyotrophy	1.8%
614	Diabetic Autonomic Neuropathy	1.8%
615	Sleep Talking	1.8%
616	Manganese Poisoning	1.8%
617	Sleep Disorders, Intrinsic	1.8%
618	Orthostatic intolerance	1.8%
619	Alcohol Withdrawal Seizures	1.8%
620	Anosmia	1.8%
621	Ataxia	1.8%
622	Athetosis	1.8%
623	Catalepsy	1.8%
624	Dystonia	1.8%
625	Hemiplegia	1.8%
626	Locked-In Syndrome	1.8%
627	Meningeal Neoplasms	1.8%
628	Meningomyelocele	1.8%
629	Muscle Hypertonia	1.8%
630	Muscle hypotonia	1.8%
631	Myoclonus	1.8%
632	Myotonia	1.8%
633	Neuralgia	1.8%
634	Paraplegia	1.8%
635	Pseudobulbar Palsy	1.8%
636	Quadriplegia	1.8%
637	Spasm	1.8%
638	Spastic Paraplegia	1.8%
639	Status Epilepticus	1.8%
640	Taste Disorders	1.8%
641	Tremor	1.8%
642	West Nile Fever	1.8%
643	Spina Bifida	1.8%
644	Monoplegia	1.8%
645	Hypokinesia	1.8%
646	Paraparesis	1.8%
647	Bradykinesia	1.8%
648	Waxy flexibility	1.8%
649	Action Tremor	1.8%
650	Resting Tremor	1.8%
651	Dysosmia	1.8%
652	Quadriparesis	1.8%
653	Mercury Poisoning, Nervous System	1.8%
654	Olfaction Disorders	1.8%
655	Myokymia	1.8%
656	Lead Poisoning, Nervous System	1.8%
657	Vestibular Neuronitis	1.8%
658	Somatosensory Disorders	1.8%
659	Neuropathic pain	1.8%
660	Hyperkinesia	1.8%
661	Intention tremor	1.8%
662	Coma, Post-Head Injury	1.8%
663	Lyme Neuroborreliosis	1.7%
664	Dyspnea, Paroxysmal	1.6%
665	Akathisia	1.6%
666	Restlessness	1.6%
667	Psychomotor Agitation	1.6%
668	Prolactinoma	1.6%
669	Growth Hormone-Secreting Pituitary Adenoma	1.6%
670	Menkes Kinky Hair Syndrome	1.6%
671	Romano-Ward Syndrome	1.6%
672	Multiple Sclerosis, Chronic Progressive	1.6%
673	Multiple Sclerosis, Relapsing-Remitting	1.6%
674	Aortic Valve Prolapse	1.6%
675	Tricuspid Valve Prolapse	1.6%
676	Takotsubo Cardiomyopathy	1.6%
677	Tarsal Tunnel Syndrome	1.6%
678	Cauda Equina Syndrome	1.6%
679	Myotonic Dystrophy	1.5%
680	Vision Disorders	1.5%
681	Metamorphopsia	1.5%
682	Visual Impairment	1.5%
683	Fibromyalgia	1.5%
684	Medial Tibial Stress Syndrome	1.5%
685	Facial Hemiatrophy	1.5%
686	Melkersson-Rosenthal Syndrome	1.5%
687	Mitochondrial Myopathies	1.5%
688	Anisocoria	1.5%
689	Confusion	1.5%
690	Facial paralysis	1.5%
691	Lethargy	1.5%
692	Memory Disorders	1.5%
693	Muscle Cramp	1.5%
694	Perceptual Disorders	1.5%
695	Psychomotor Disorders	1.5%
696	Tonic Pupil	1.5%
697	Eosinophilia-Myalgia Syndrome	1.5%
698	Anhedonia	1.5%
699	Disorientation	1.5%
700	Facial Paresis	1.5%
701	Memory Loss	1.5%
702	Hemisensory Neglect	1.5%
703	Dysacusis	1.5%
704	Sleep Bruxism	1.5%
705	Toxoplasmosis, Congenital	1.5%
706	Anencephaly	1.5%
707	Meningocele	1.5%
708	Muscular Atrophy	1.5%
709	Respiratory Paralysis	1.5%
710	Encephalocele	1.5%
711	Malaria, Cerebral	1.5%
712	Tetany	1.4%
713	Neurocysticercosis	1.4%
714	Zellweger Syndrome	1.4%
715	Nelson Syndrome	1.4%
716	Gait Apraxia	1.4%
717	Sciatic Neuropathy	1.3%
718	Ulnar Neuropathies	1.3%
719	Lesion of Sciatic Nerve	1.3%
720	Ulnar Neuritis	1.3%
721	Radial nerve compression	1.3%
722	Radial Tunnel Syndrome	1.3%
723	Peroneal Neuropathies	1.3%
724	Radial Neuropathy	1.3%
725	Median Neuropathy	1.3%
726	Sciatic Nerve Palsy	1.3%
727	Femoral Neuropathy	1.3%
728	Tibial Neuropathy	1.3%
729	Ulnar Nerve Palsy	1.3%
730	Postural Orthostatic Tachycardia Syndrome	1.3%
731	Radial nerve palsy	1.3%
732	Acoustic Neuroma	1.3%
733	Carpal Tunnel Syndrome	1.3%
734	neurofibroma	1.3%
735	Sciatica	1.3%
736	Kearns-Sayre syndrome	1.3%
737	Tachycardia, Atrioventricular Nodal Reentry	1.3%
738	Tachycardia, Ectopic Atrial	1.3%
739	Tachycardia, Ectopic Junctional	1.3%
740	Sinus Tachycardia	1.3%
741	Torsades de Pointes	1.3%
742	Accelerated Idioventricular Rhythm	1.3%
743	Truncus Arteriosus, Persistent	1.3%
744	Duane Retraction Syndrome	1.3%
745	Amyloid Neuropathies, Familial	1.3%
746	Alstrom Syndrome	1.3%
747	Consciousness Disorders	1.2%
748	Mental Retardation	1.2%
749	Muscle Weakness	1.2%
750	Depressed Level of Consciousness	1.2%
751	Mental deficiency	1.2%
752	Intellectual Disability	1.2%
753	Mobius Syndrome	1.2%
754	Bell Palsy	1.2%
755	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.2%
756	Catatonia	1.2%
757	Herpes Zoster Oticus	1.2%
758	Familial Periodic Paralysis	1.2%
759	Aphonia	1.2%
760	Sleep Deprivation	1.2%
761	Dysphonia	1.2%
762	Williams Syndrome	1.2%
763	Sinus Arrest, Cardiac	1.2%
764	Optic Nerve Glioma	1.2%
765	Glycogen storage disease type II	1.1%
766	Waterhouse-Friderichsen Syndrome	1.1%
767	Turner Syndrome	1.1%
768	Myalgia	1%
769	Neuronal Ceroid-Lipofuscinoses	1%
770	Esotropia	1%
771	Exotropia	1%
772	Sleep Apnea Syndromes	1%
773	Polymyositis	1%
774	Disorders of Excessive Somnolence	1%
775	Sleep Initiation and Maintenance Disorders	1%
776	Night Terrors	1%
777	Somnambulism	1%
778	Trigeminal Nerve Disorder	1%
779	Transient Insomnia	1%
780	Sleep Paralysis	1%
781	Chronic Insomnia	1%
782	REM Sleep Behavior Disorder	1%
783	Hypersomnia	1%
784	Dermal Sinus	1%
785	Dysgeusia	1%
786	Formication	1%
787	Hyperalgesia	1%
788	Hyperesthesia	1%
789	Hypesthesia	1%
790	Language Disorders	1%
791	Numbness	1%
792	Paresthesia	1%
793	Paraparesis, Spastic	1%
794	Spina Bifida Cystica	1%
795	Trismus	1%
796	Spina Bifida Occulta	1%
797	Epilepsia Partialis Continua	1%
798	Hypogeusia	1%
799	Meningeal Carcinomatosis	1%
800	Brown-Sequard Syndrome	1%
801	Lissencephaly	1%
802	Polymicrogyria	1%
803	Pachygyria	1%
804	Schizencephaly	1%
805	Lockjaw	1%
806	Allodynia	1%
807	Lead Poisoning, Nervous System, Childhood	1%
808	Lead Poisoning, Nervous System, Adult	1%
809	Periventricular Nodular Heterotopia	1%
810	Ageusia	1%
811	Cubital Tunnel Syndrome	1%
812	Aicardi's syndrome	0.9%
813	Hoarseness	0.9%
814	Cockayne Syndrome	0.9%
815	Alcohol Withdrawal Delirium	0.9%
816	Classical Lissencephalies and Subcortical Band Heterotopias	0.9%
817	Eye Injuries	0.8%
818	Muscular Dystrophy	0.8%
819	Congenital nystagmus	0.8%
820	Orbital Myositis	0.8%
821	Holoprosencephaly	0.8%
822	Diplopia	0.8%
823	Muscle Rigidity	0.8%
824	Muscle Spasticity	0.8%
825	Scotoma	0.8%
826	Photophobia	0.8%
827	Cogwheel Rigidity	0.8%
828	Hemifacial Spasm	0.8%
829	Amaurosis	0.8%
830	Blindness	0.8%
831	Nuchal Rigidity	0.8%
832	Pyomyositis	0.8%
833	Agnosia	0.8%
834	Apraxias	0.8%
835	Hallucinations	0.8%
836	Hemianopsia	0.8%
837	Hyperacusis	0.8%
838	Tinnitus	0.8%
839	Visual Agnosia	0.8%
840	Anosognosia	0.8%
841	Wernicke-Korsakoff Syndrome	0.8%
842	Phonophobia	0.8%
843	Hearing Loss	0.8%
844	Sarcopenia	0.8%
845	Polyradiculopathy	0.8%
846	Gaucher Disease	0.8%
847	Optic Atrophy, Hereditary, Leber	0.7%
848	Kartagener Syndrome	0.7%
849	Alexia	0.7%
850	Dyslexia	0.7%
851	Amnesia	0.7%
852	Delirium	0.7%
853	Dissociative Amnesia	0.7%
854	Color blindness	0.7%
855	Global Amnesia	0.7%
856	Cri-du-Chat Syndrome	0.7%
857	Down Syndrome	0.7%
858	Trisomy 21	0.7%
859	POEMS Syndrome	0.7%
860	Meningioma	0.7%
861	Microcephaly	0.7%
862	Macrocephaly	0.7%
863	Hypokalemic periodic paralysis	0.7%
864	Porencephaly	0.7%
865	Sleep Apnea, Obstructive	0.6%
866	Sleep Apnea, Central	0.6%
867	Narcolepsy	0.6%
868	Trigeminal Neuralgia	0.6%
869	Kleine-Levin Syndrome	0.6%
870	Agraphia	0.6%
871	Anomia	0.6%
872	Cluttering	0.6%
873	Language Development Disorders	0.6%
874	Speech Disorders	0.6%
875	Syncope	0.6%
876	Stupor	0.6%
877	Dysgraphia	0.6%
878	Presyncope	0.6%
879	Dyslalia	0.6%
880	Prader-Willi Syndrome	0.6%
881	Niemann-Pick Disease, Type C	0.6%
882	Phantom pain	0.6%
883	Phantom Limb Pain	0.6%
884	Neurofibrosarcoma	0.6%
885	Tay-Sachs Disease	0.6%
886	Eye Burns	0.5%
887	Welander Distal Myopathy	0.5%
888	Amaurosis Fugax	0.5%
889	Blindness, Cortical	0.5%
890	Dyscalculia	0.5%
891	Rett Syndrome	0.5%
892	Deafness	0.5%
893	Hearing Loss, Sudden	0.5%
894	Gerstmann Syndrome	0.5%
895	Hearing Loss, Bilateral	0.5%
896	Hearing Loss, High-Frequency	0.5%
897	Hearing Loss, Mixed Conductive-Sensorineural	0.5%
898	Prosopagnosia	0.5%
899	Apraxia, Ideomotor	0.5%
900	Charles Bonnet Syndrome	0.5%
901	Hearing Loss, Unilateral	0.5%
902	Complete Hearing Loss	0.5%
903	Alien Hand Syndrome	0.5%
904	Deaf Mutism	0.5%
905	Rubinstein-Taybi Syndrome	0.5%
906	Dermatomyositis	0.4%
907	Corneal Scar	0.4%
908	Muscular Dystrophy, Duchenne	0.4%
909	Retrograde amnesia	0.4%
910	Amnesia, Anterograde	0.4%
911	Cataplexy	0.4%
912	Aphasia	0.4%
913	Articulation Disorders	0.4%
914	Echolalia	0.4%
915	Stuttering	0.4%
916	Dysphasia	0.4%
917	Fragile X Syndrome	0.3%
918	Mutism	0.3%
919	Selective Mutism	0.3%
920	Dysarthria	0.3%
921	Corneal Perforation	0.3%
922	Mucopolysaccharidosis II	0.2%
923	Alexia, Pure	0.2%

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