MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Prurigo

(UMLS:C0033771)

Definition:: A name applied to several itchy skin eruptions of unknown cause. The characteristic course is the formation of a dome-shaped papule with a small transient vesicle on top, followed by crusting over or lichenification. (From Dorland, 27th ed)
UMLS ID:: C0033771
MeSH ID:: D011536

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.674

Synonym(s)

Prurigo

Itchy skin eruption

Itchy skin eruption, NOS

Prurigo, NOS

Pruritic rash

Pruritic rash, NOS

Rash pruritic

itchy rash

prurigo

10.

pruritic rash

11.

rash itchy

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Amoxicillin	FAERS: 10		US FAERS
2	Amoxicillin-Potassium Clavulanate Combination	FAERS: 7		US FAERS
3	Ciprofloxacin	FAERS: 7		SIDER US FAERS
4	Levofloxacin	FAERS: 6		US FAERS
5	Cyclosporine	FAERS: 3		US FAERS
6	Imatinib Mesylate	FAERS: 3		US FAERS
7	Lamotrigine	FAERS: 3		US FAERS
8	Tacrolimus	FAERS: 3		US FAERS
9	Terbinafine	FAERS: 3		US FAERS
10	Voriconazole	FAERS: 3		US FAERS
11	Amiodarone	FAERS: 2		US FAERS
12	Amoxicillin	FAERS: 2		US FAERS
13	Fenofibrate	FAERS: 2		US FAERS
14	Paliperidone Palmitate	FAERS: 2		US FAERS
15	Ranolazine	FAERS: 2		US FAERS
16	Rivaroxaban	FAERS: 2		US FAERS
17	atovaquone, proguanil drug combination	FAERS: 2		US FAERS
18	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 1		US FAERS
19	Carbamazepine	FAERS: 1		US FAERS
20	Cefixime	FAERS: 1		US FAERS
21	Celecoxib	FAERS: 1		US FAERS
22	Ciprofloxacin	FAERS: 1		US FAERS
23	Citalopram	FAERS: 1		US FAERS
24	Clarithromycin	FAERS: 1		US FAERS
25	Diclofenac	FAERS: 1		US FAERS
26	Donepezil	FAERS: 1		US FAERS
27	Everolimus	FAERS: 1		US FAERS
28	Fluticasone	FAERS: 1		US FAERS
29	Glipizide	FAERS: 1		US FAERS
30	Hydrochlorothiazide	FAERS: 1		US FAERS
31	INCB018424	FAERS: 1		US FAERS
32	Ibuprofen	FAERS: 1		US FAERS
33	Ketotifen	FAERS: 1		US FAERS
34	Lidocaine	FAERS: 1		US FAERS
35	Liraglutide	FAERS: 1		US FAERS
36	Losartan	FAERS: 1		US FAERS
37	Modafinil	FAERS: 1		US FAERS
38	Nitrofurantoin	FAERS: 1		US FAERS
39	NuvaRing	FAERS: 1		US FAERS
40	PCI 32765	FAERS: 1		US FAERS
41	Piroxicam	FAERS: 1		US FAERS
42	Povidone-Iodine	FAERS: 1		US FAERS
43	Pregabalin	FAERS: 1		US FAERS
44	Rivastigmine	FAERS: 1		US FAERS
45	Sitagliptin Phosphate	FAERS: 1		US FAERS
46	Spironolactone	FAERS: 1		US FAERS
47	Thyroxine	FAERS: 1		US FAERS
48	Trimethoprim, Sulfamethoxazole Drug Combination	FAERS: 1		US FAERS
49	Valacyclovir	FAERS: 1		US FAERS
50	Valsartan	FAERS: 1		US FAERS
51	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
52	apixaban	FAERS: 1		US FAERS
53	cefuroxime axetil	FAERS: 1		US FAERS
54	dolutegravir	FAERS: 1		SIDER US FAERS
55	iopromide	FAERS: 1		US FAERS
56	macitentan	FAERS: 1		US FAERS
57	pazopanib	FAERS: 1		US FAERS
58	pimecrolimus	FAERS: 1		US FAERS
59	rofecoxib	FAERS: 1		US FAERS
60	Aprepitant			SIDER
61	Azacitidine			SIDER
62	Bupivacaine			SIDER
63	Bupropion			SIDER
64	Canagliflozin			SIDER
65	Capecitabine			SIDER
66	Caspofungin			SIDER
67	Clindamycin			SIDER
68	Clofarabine			SIDER
69	Cyclophosphamide			SIDER
70	Darunavir			SIDER
71	Dasatinib			SIDER
72	Docetaxel			SIDER
73	Duloxetine Hydrochloride			SIDER
74	Econazole			SIDER
75	Emtricitabine			SIDER
76	Estradiol			SIDER
77	Febuxostat			SIDER
78	Fosinopril			SIDER
79	Hydrocortisone			SIDER
80	Ibandronic Acid			SIDER
81	Icodextrin			SIDER
82	Lasofoxifene			SIDER
83	Lenalidomide			SIDER
84	Mannitol			SIDER
85	Melatonin			SIDER
86	Mesalamine			SIDER
87	N-(3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl)-3-(2-((((1,1-dimethylethyl)amino)carbonyl)amino)-3,3-dimethyl-1-oxobutyl)-6,6-dimethyl-3-azabicyclo(3.1.0)hexan-2-carboxamide			SIDER
88	Norethindrone			SIDER
89	OPC-67683			SIDER
90	Paclitaxel			SIDER
91	Palonosetron			SIDER
92	Raltegravir Potassium			SIDER
93	Saquinavir			SIDER
94	Semaxinib			SIDER
95	Sunitinib			SIDER
96	Tenofovir			SIDER
97	Thalidomide		View details 2985516 2986670 6093713 6703734 10918274 12629253 12755975 15262695 17852637 19548950	CTD
98	Tigecycline			SIDER
99	Tolvaptan			SIDER
100	Tramadol			SIDER
101	Venlafaxine Hydrochloride			SIDER
102	Zalcitabine			SIDER
103	bosutinib			SIDER
104	dabrafenib			SIDER
105	etravirine			SIDER
106	fosaprepitant			SIDER
107	paricalcitol			SIDER
108	pazopanib			SIDER
109	pirfenidone			SIDER
110	ponatinib			SIDER
111	posaconazole			SIDER
112	ropinirole			SIDER
113	rotigotine			SIDER
114	temsirolimus			SIDER
115	tipranavir			SIDER
116	trametinib			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Pyoderma Gangrenosum	45.8%
2	Breast Diseases	42.9%
3	Dermatitis	42.9%
4	Exanthema	42.9%
5	Facial Dermatoses	42.9%
6	Hair Diseases	42.9%
7	Hand Dermatoses	42.9%
8	keratoacanthoma	42.9%
9	Keratosis	42.9%
10	Nail Diseases	42.9%
11	Photosensitivity Disorders	42.9%
12	Pyoderma	42.9%
13	Rosacea	42.9%
14	Sebaceous Gland Diseases	42.9%
15	Skin Diseases, Vesiculobullous	42.9%
16	Skin Ulcer	42.9%
17	Sweat Gland Diseases	42.9%
18	Skin Diseases, Papulosquamous	42.9%
19	Skin Diseases, Vascular	42.9%
20	Acneiform Eruptions	42.9%
21	Ocular Rosacea	42.9%
22	Subcorneal pustular dermatosis	42.9%
23	Erythematotelangiectatic Rosacea	42.9%
24	Papulopustular Rosacea	42.9%
25	Chronic Actinic Dermatitis	42.9%
26	Acne Vulgaris	40.9%
27	Contact Dermatitis	40.9%
28	Eczema	40.9%
29	Erythema Multiforme	40.9%
30	Intertrigo	40.9%
31	Neurodermatitis	40.9%
32	Rhinophyma	40.9%
33	Perioral Dermatitis	40.9%
34	Acne	40.9%
35	Lupus Erythematosus, Cutaneous	38.1%
36	Panniculitis	38.1%
37	Systemic Scleroderma	38.1%
38	Morphea	38.1%
39	Dermatitis, Phototoxic	37.2%
40	Pityriasis Lichenoides et Varioliformis Acuta	37.2%
41	Pityriasis Lichenoides	37.2%
42	Phototoxicity	37.2%
43	Foot Ulcer	37.1%
44	Dermatitis, Irritant	33.3%
45	Acne Conglobata	33.3%
46	Anhidrosis	31%
47	Cholesteatoma	31%
48	Pressure Ulcer	31%
49	Dermatitis Herpetiformis	31%
50	Folliculitis	31%
51	Foot Dermatoses	31%
52	Gynecomastia	31%
53	Hypertrichosis	31%
54	Hypohidrosis	31%
55	Hypotrichosis	31%
56	Leg Ulcer	31%
57	Miliaria	31%
58	Parakeratosis	31%
59	Parapsoriasis	31%
60	Pityriasis	31%
61	Psoriasis	31%
62	Sweet Syndrome	31%
63	Hidradenitis	31%
64	Onycholysis	31%
65	Miliaria Rubra	31%
66	Hyperpigmentation	31%
67	Lichenoid Eruptions	31%
68	Chloracne	31%
69	Acrodermatitis	30.5%
70	Sebaceous Gland Neoplasms	30.5%
71	Porokeratosis	30.5%
72	Gianotti-Crosti Syndrome	30.5%
73	Keratoderma, Palmoplantar	30.5%
74	Dermatitis, Atopic	30.3%
75	Epidermolysis Bullosa	30.3%
76	Foot Diseases	30%
77	Diaper Rash	29.7%
78	Dermatitis, Photoallergic	29.6%
79	Panniculitis, Lupus Erythematosus	29.3%
80	Skin Abnormalities	28.6%
81	Skin Diseases, Infectious	28.6%
82	Skin Neoplasms	28.6%
83	Pigmentation Disorders	28.6%
84	Lipomatosis	27.9%
85	Pruritus	27.9%
86	Erythema	27.9%
87	Necrolytic Migratory Erythema	27.9%
88	Cutaneous Fistula	27.9%
89	Nephrogenic Fibrosing Dermopathy	27.9%
90	Nephrogenic Systemic Fibrosis	27.9%
91	Necrobiosis Lipoidica Diabeticorum	27.5%
92	Urticaria Pigmentosa	27.3%
93	Lupus Erythematosus, Discoid	27.3%
94	Scleroderma, Limited	27.3%
95	Xeroderma Pigmentosum	27.1%
96	Dermatitis, Occupational	26.3%
97	Lichen Planus	25.4%
98	Melanosis	25.4%
99	Chloasma	25.4%
100	Pityriasis Rosea	25.4%
101	Pityriasis Rubra Pilaris	25.4%
102	Vitiligo	25.4%
103	Lichen Nitidus	25.4%
104	Dermatitis, Allergic Contact	25%
105	Papillon-Lefevre Disease	24.8%
106	Xeroderma	24.7%
107	Connective Tissue Diseases	23.1%
108	Erythema Induratum	22.8%
109	Acanthosis Nigricans	22.7%
110	Alopecia Areata	22.7%
111	Lentigo	22.7%
112	Erythema Infectiosum	22.4%
113	Cutis Laxa	22.4%
114	Exanthema Subitum	22.3%
115	Erythema Nodosum	21.9%
116	Dermatomyositis	21.8%
117	Toxic Epidermal Necrolysis	21.1%
118	Stevens-Johnson Syndrome	21.1%
119	Acantholysis	20.9%
120	Breast Cyst	20.9%
121	Actinic keratosis	20.9%
122	Pemphigoid, Benign Mucous Membrane	20.9%
123	Pemphigus	20.9%
124	Piedra	20.9%
125	Sunburn	20.9%
126	Tinea Capitis	20.7%
127	Onychomycosis	20.7%
128	Mastocytosis	20.5%
129	Argyria	20.5%
130	Hirsutism	20.5%
131	Lactation Disorder	20.5%
132	Mastitis	20.5%
133	Urticaria	20.5%
134	Adiposis Dolorosa	20.2%
135	Ectodermal Dysplasia	20.2%
136	Pruritus Vulvae	20.2%
137	Aplasia Cutis Congenita	20.2%
138	Mastocytoma	20.1%
139	Pruritus Ani	20.1%
140	Hyperkeratosis, Epidermolytic	19.5%
141	Granuloma Annulare	19.3%
142	Pseudoxanthoma Elasticum	18.6%
143	Ecthyma	18.2%
144	Alopecia	17.2%
145	Sweating, Gustatory	17.2%
146	Androgenetic Alopecia	17.2%
147	Auriculotemporal Syndrome	17.2%
148	Lice Infestations	16.9%
149	Varicose Ulcer	16.9%
150	Breast Neoplasms, Male	16.9%
151	Triple Negative Breast Neoplasms	16.9%
152	Galactorrhea	16.7%
153	Hidradenitis Suppurativa	16.6%
154	Ichthyosis, X-Linked	15.8%
155	Behcet Syndrome	15.8%
156	Sjogren-Larsson Syndrome	15.7%
157	Dermatomycoses	15.5%
158	Mucocutaneous Lymph Node Syndrome	15.5%
159	Skin Diseases, Bacterial	15.5%
160	Tinea Pedis	15.5%
161	Lichen Planus, Oral	15.4%
162	Drug Eruptions	15.3%
163	Lipodystrophy	15.3%
164	Livedo Reticularis	15.3%
165	Malignant Atrophic Papulosis	15.3%
166	Polyarteritis Nodosa	15%
167	Takayasu Arteritis	15%
168	Collagen Diseases	14.3%
169	Mixed Connective Tissue Disease	14.3%
170	Mucinoses	14.3%
171	Albinism	13.8%
172	Erythema Chronicum Migrans	13.5%
173	Larva Migrans	12.8%
174	Leishmaniasis	12.8%
175	Molluscum Contagiosum	12.8%
176	Angioedema	12.7%
177	Onchocerciasis	12.6%
178	Chromoblastomycosis	12.5%
179	Dermatophytosis	12.5%
180	Nail-Patella Syndrome	12.5%
181	Sporotrichosis	12.5%
182	Tinea	12.5%
183	Tinea Versicolor	12.5%
184	Trichophytosis	12.5%
185	Hyalohyphomycosis	12.5%
186	Acute Generalized Exanthematous Pustulosis	12.4%
187	Porphyrias, Hepatic	12.3%
188	Mycetoma	12.3%
189	Leishmaniasis, Cutaneous	11.2%
190	Eczema Herpeticum	11.2%
191	Fusariosis	11.1%
192	Hereditary Angioedema Type III	10.4%
193	Hereditary Angioedema Types I and II	10.4%
194	Scleromyxedema	10.3%
195	Warts	10.3%
196	Candidiasis, Chronic Mucocutaneous	10%
197	Cutaneous Candidiasis	10%
198	Cartilage Diseases	10%
199	Rheumatism	10%
200	Chondromalacia	10%
201	Erysipelas	9.9%
202	Serum Sickness	9.9%
203	Staphylococcal Skin Infections	9.9%
204	Variegate Porphyria	9.9%
205	Acute intermittent porphyria	9.9%
206	Porphyria Cutanea Tarda	9.9%
207	Erythrasma	9.9%
208	Carcinoma, Lobular	9.9%
209	Arthritis, Psoriatic	9.9%
210	Lupus Erythematosus, Systemic	9.5%
211	Overlap syndrome	9.5%
212	CREST Syndrome	9.4%
213	Angioedemas, Hereditary	9.1%
214	Epidermodysplasia Verruciformis	9%
215	Herpes Labialis	9%
216	Diabetic Foot	8.9%
217	Staphylococcal Scalded Skin Syndrome	8.8%
218	Peutz-Jeghers Syndrome	8.6%
219	carbuncle	8.2%
220	Condylomata Acuminata	7.5%
221	Furunculosis	7.4%
222	furuncle	7.4%
223	Giant Cell Arteritis	7.4%
224	Temporal Arteritis	7.4%
225	Impetigo	7.3%
226	Blastomycosis	7.1%
227	HIV-Associated Lipodystrophy Syndrome	7%
228	Mesenteric Panniculitis	7%
229	Panniculitis, Peritoneal	7%
230	Tietze's Syndrome	7%
231	Orbital Cellulitis	7%
232	Myxoid cyst	7%
233	Myxedema	6.8%
234	Dupuytren Contracture	6.8%
235	Rhinoscleroma	6.4%
236	Cellulitis	5.4%
237	Menkes Kinky Hair Syndrome	5.3%
238	Osteochondritis	5.3%
239	Polymyalgia Rheumatica	5.3%
240	Osteogenesis Imperfecta	5.1%
241	Keloid	5%
242	Rheumatoid Arthritis	4.2%
243	Rheumatoid Nodule	4.2%
244	Juvenile arthritis	4.2%
245	Lupus Nephritis	4%
246	Noonan Syndrome	3.8%
247	Laryngomalacia	3.5%
248	Pectus carinatum	3.4%
249	Marfan Syndrome	3.4%
250	Felty Syndrome	3.3%
251	Bronchomalacia	3.3%
252	Tracheomalacia	3.3%
253	Homocystinuria	3.3%
254	Rheumatoid Vasculitis	2.8%
255	Mucopolysaccharidosis III	2.7%
256	Sicca Syndrome	2.4%
257	Sjogren's Syndrome	2.4%
258	Mucopolysaccharidosis II	1.8%
259	Lupus Vasculitis, Central Nervous System	1.6%

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