MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hidradenitis

(UMLS:C0085160)

Definition:: The inflammation of a sweat gland (usually of the apocrine type). The condition can be idiopathic or occur as a result of or in association with another underlying condition. Neutrophilic eccrine hidradenitis is a relatively rare variant that has been reported in patients undergoing chemotherapy, usually for non-Hodgkin lymphomas or leukemic conditions.
UMLS ID:: C0085160
MeSH ID:: D016575

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.946.315

Synonym(s)

Hidradenitis

HIDRADENITIS

Hydradenitis

hidradenitis

hidrosadenitis

hydradenitis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Isotretinoin	FAERS: 31 Canada Vigilance: 1	Canada Vigilance US FAERS
2	NuvaRing	FAERS: 9	OFFSIDES US FAERS
3	tofacitinib	FAERS: 6 Canada Vigilance: 1	Canada Vigilance US FAERS
4	Azathioprine	FAERS: 5	US FAERS
5	Clozapine	FAERS: 5	US FAERS
6	Decitabine	FAERS: 5	US FAERS
7	etonogestrel	FAERS: 5	US FAERS
8	teriflunomide	FAERS: 5	US FAERS
9	Testosterone	FAERS: 4	US FAERS
10	Cytarabine	FAERS: 3	OFFSIDES US FAERS
11	Dimethyl Fumarate	FAERS: 3	US FAERS
12	Nicotine	FAERS: 3	US FAERS
13	Norgestrel	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
14	Ruxolitinib phosphate	FAERS: 3	US FAERS
15	Teriparatide	FAERS: 3	US FAERS
16	ambrisentan	FAERS: 3	US FAERS
17	rofecoxib	FAERS: 3	OFFSIDES US FAERS
18	Carbamazepine	FAERS: 2	US FAERS
19	Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination	FAERS: 2	US FAERS
20	Exenatide	FAERS: 2	US FAERS
21	Finasteride	FAERS: 2	US FAERS
22	Fingolimod Hydrochloride	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
23	Imatinib Mesylate	FAERS: 2	US FAERS
24	Vemurafenib	FAERS: 2	US FAERS
25	apremilast	FAERS: 2	US FAERS
26	17 alpha-Hydroxyprogesterone Caproate	FAERS: 1	US FAERS
27	Alprazolam	FAERS: 1	US FAERS
28	Aripiprazole	FAERS: 1	US FAERS
29	Azacitidine	FAERS: 1	US FAERS
30	Azelaic acid	FAERS: 1	US FAERS
31	Cabozantinib S-malate	FAERS: 1	US FAERS
32	Cinacalcet	FAERS: 1	US FAERS
33	Duloxetine Hydrochloride	FAERS: 1	US FAERS
34	Everolimus	FAERS: 1	US FAERS
35	Glatiramer Acetate	FAERS: 1	US FAERS
36	Levofloxacin	FAERS: 1	US FAERS
37	Lisinopril	FAERS: 1	US FAERS
38	Methotrexate	FAERS: 1	US FAERS
39	Minocycline	FAERS: 1	US FAERS
40	Modafinil	FAERS: 1	US FAERS
41	Rivaroxaban	FAERS: 1	US FAERS
42	Sirolimus	FAERS: 1	US FAERS
43	Sunitinib	FAERS: 1	US FAERS
44	Thioguanine	FAERS: 1	US FAERS
45	Thyroxine	FAERS: 1	US FAERS
46	dabrafenib	FAERS: 1	US FAERS
47	palbociclib	FAERS: 1	US FAERS
48	Acenocoumarol		OFFSIDES
49	Bortezomib		OFFSIDES
50	Butorphanol		OFFSIDES
51	Calcium Carbonate		OFFSIDES
52	Capecitabine		OFFSIDES
53	Cephalexin		OFFSIDES
54	Ciclopirox		OFFSIDES
55	Clindamycin		OFFSIDES
56	Clonidine		OFFSIDES
57	Dexamethasone		OFFSIDES
58	Dipyrone		OFFSIDES
59	Dutasteride		OFFSIDES
60	Erythromycin		OFFSIDES
61	Etoposide		OFFSIDES
62	Fludrocortisone		OFFSIDES
63	Flurazepam		OFFSIDES
64	Hydralazine		OFFSIDES
65	Hydromorphone		OFFSIDES
66	Ibuprofen		OFFSIDES
67	Lenalidomide		OFFSIDES
68	Lidoderm		OFFSIDES
69	Loperamide		OFFSIDES
70	Medroxyprogesterone Acetate		OFFSIDES
71	Melatonin		OFFSIDES
72	Memantine		OFFSIDES
73	Meperidine		OFFSIDES
74	Mesalamine		OFFSIDES
75	Methotrexate		SIDER
76	Metolazone		OFFSIDES
77	Nitrous Oxide		OFFSIDES
78	Nortriptyline		OFFSIDES
79	Pamidronate		OFFSIDES
80	Penicillin V		OFFSIDES
81	Prednisone		OFFSIDES
82	Scopolamine		OFFSIDES
83	Tamsulosin		OFFSIDES
84	Temazepam		OFFSIDES
85	Tretinoin		OFFSIDES
86	Vitamin D		OFFSIDES
87	Zoledronic Acid		OFFSIDES
88	alfuzosin		OFFSIDES
89	cyclobenzaprine		OFFSIDES
90	fludarabine		OFFSIDES
91	zolmitriptan		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Anhidrosis	46.7%
2	Hypohidrosis	46.7%
3	Miliaria	46.7%
4	Miliaria Rubra	46.7%
5	Breast Diseases	31%
6	Dermatitis	31%
7	Exanthema	31%
8	Facial Dermatoses	31%
9	Hair Diseases	31%
10	Hand Dermatoses	31%
11	keratoacanthoma	31%
12	Keratosis	31%
13	Nail Diseases	31%
14	Photosensitivity Disorders	31%
15	Prurigo	31%
16	Pyoderma	31%
17	Rosacea	31%
18	Sebaceous Gland Diseases	31%
19	Skin Diseases, Vesiculobullous	31%
20	Skin Ulcer	31%
21	Skin Diseases, Papulosquamous	31%
22	Skin Diseases, Vascular	31%
23	Acneiform Eruptions	31%
24	Ocular Rosacea	31%
25	Subcorneal pustular dermatosis	31%
26	Erythematotelangiectatic Rosacea	31%
27	Papulopustular Rosacea	31%
28	Chronic Actinic Dermatitis	31%
29	Pyoderma Gangrenosum	30%
30	Lupus Erythematosus, Cutaneous	27.9%
31	Panniculitis	27.9%
32	Systemic Scleroderma	27.9%
33	Morphea	27.9%
34	Acne Vulgaris	26.7%
35	Contact Dermatitis	26.7%
36	Eczema	26.7%
37	Erythema Multiforme	26.7%
38	Intertrigo	26.7%
39	Neurodermatitis	26.7%
40	Rhinophyma	26.7%
41	Perioral Dermatitis	26.7%
42	Acne	26.7%
43	Sweating, Gustatory	23.6%
44	Auriculotemporal Syndrome	23.6%
45	Foot Ulcer	23.1%
46	Foot Diseases	22%
47	Dermatitis, Phototoxic	22%
48	Pityriasis Lichenoides et Varioliformis Acuta	22%
49	Pityriasis Lichenoides	22%
50	Phototoxicity	22%
51	Skin Abnormalities	20.9%
52	Skin Diseases, Infectious	20.9%
53	Skin Neoplasms	20.9%
54	Pigmentation Disorders	20.9%
55	Lipomatosis	20.5%
56	Pruritus	20.5%
57	Erythema	20.5%
58	Necrolytic Migratory Erythema	20.5%
59	Cutaneous Fistula	20.5%
60	Nephrogenic Fibrosing Dermopathy	20.5%
61	Nephrogenic Systemic Fibrosis	20.5%
62	Dermatitis Herpetiformis	20.3%
63	Acrodermatitis	20%
64	Cholesteatoma	20%
65	Pressure Ulcer	20%
66	Dermatitis, Atopic	20%
67	Epidermolysis Bullosa	20%
68	Folliculitis	20%
69	Foot Dermatoses	20%
70	Gynecomastia	20%
71	Hypertrichosis	20%
72	Hypotrichosis	20%
73	Leg Ulcer	20%
74	Parakeratosis	20%
75	Parapsoriasis	20%
76	Pityriasis	20%
77	Psoriasis	20%
78	Sebaceous Gland Neoplasms	20%
79	Sweet Syndrome	20%
80	Onycholysis	20%
81	Hyperpigmentation	20%
82	Porokeratosis	20%
83	Lichenoid Eruptions	20%
84	Gianotti-Crosti Syndrome	20%
85	Chloracne	20%
86	Keratoderma, Palmoplantar	20%
87	Dermatitis, Irritant	19.6%
88	Acne Conglobata	19.6%
89	Connective Tissue Diseases	18.5%
90	Panniculitis, Lupus Erythematosus	18.4%
91	Xeroderma Pigmentosum	17.9%
92	Necrobiosis Lipoidica Diabeticorum	17.9%
93	Lupus Erythematosus, Discoid	17.8%
94	Scleroderma, Limited	17.8%
95	Dermatitis, Photoallergic	17.5%
96	Urticaria Pigmentosa	17.1%
97	Xeroderma	16.2%
98	Dermatomyositis	16.2%
99	Diaper Rash	16.1%
100	Dermatitis, Occupational	15.5%
101	Cutis Laxa	15.3%
102	Mastocytosis	15.1%
103	Lichen Planus	14.8%
104	Melanosis	14.8%
105	Chloasma	14.8%
106	Pityriasis Rosea	14.8%
107	Pityriasis Rubra Pilaris	14.8%
108	Vitiligo	14.8%
109	Dermatitis, Allergic Contact	14.8%
110	Lichen Nitidus	14.8%
111	Papillon-Lefevre Disease	14.6%
112	Erythema Induratum	14.4%
113	Erythema Infectiosum	14.1%
114	Exanthema Subitum	14%
115	Erythema Nodosum	13.7%
116	Acantholysis	13.6%
117	Breast Cyst	13.6%
118	Actinic keratosis	13.6%
119	Pemphigoid, Benign Mucous Membrane	13.6%
120	Pemphigus	13.6%
121	Piedra	13.6%
122	Sunburn	13.6%
123	Argyria	13.3%
124	Ectodermal Dysplasia	13.3%
125	Hirsutism	13.3%
126	Lactation Disorder	13.3%
127	Mastitis	13.3%
128	Urticaria	13.3%
129	Aplasia Cutis Congenita	13.3%
130	Adiposis Dolorosa	13.2%
131	Pruritus Vulvae	13.2%
132	Mastocytoma	13.1%
133	Pruritus Ani	13.1%
134	Tinea Capitis	12.7%
135	Onychomycosis	12.7%
136	Toxic Epidermal Necrolysis	12.6%
137	Stevens-Johnson Syndrome	12.6%
138	Pseudoxanthoma Elasticum	12.6%
139	Granuloma Annulare	12.4%
140	Acanthosis Nigricans	12.2%
141	Alopecia Areata	12.2%
142	Lentigo	12.2%
143	Ecthyma	11.5%
144	Hyperkeratosis, Epidermolytic	11%
145	Collagen Diseases	10.3%
146	Mixed Connective Tissue Disease	10.3%
147	Mucinoses	10.3%
148	Dermatomycoses	10.2%
149	Mucocutaneous Lymph Node Syndrome	10.2%
150	Skin Diseases, Bacterial	10.2%
151	Alopecia	10.1%
152	Androgenetic Alopecia	10.1%
153	Drug Eruptions	10%
154	Lipodystrophy	10%
155	Livedo Reticularis	10%
156	Malignant Atrophic Papulosis	10%
157	Behcet Syndrome	10%
158	Lice Infestations	9.9%
159	Varicose Ulcer	9.9%
160	Breast Neoplasms, Male	9.9%
161	Triple Negative Breast Neoplasms	9.9%
162	Polyarteritis Nodosa	9.8%
163	Takayasu Arteritis	9.8%
164	Ichthyosis, X-Linked	9.8%
165	Galactorrhea	9.8%
166	Sjogren-Larsson Syndrome	9.8%
167	Tinea Pedis	8.9%
168	Albinism	8.7%
169	Erythema Chronicum Migrans	8.5%
170	Lichen Planus, Oral	8.4%
171	Nail-Patella Syndrome	8.2%
172	Porphyrias, Hepatic	8.1%
173	Larva Migrans	7.6%
174	Leishmaniasis	7.6%
175	Molluscum Contagiosum	7.6%
176	Angioedema	7.5%
177	Onchocerciasis	7.5%
178	Chromoblastomycosis	7.4%
179	Dermatophytosis	7.4%
180	Sporotrichosis	7.4%
181	Tinea	7.4%
182	Tinea Versicolor	7.4%
183	Trichophytosis	7.4%
184	Hyalohyphomycosis	7.4%
185	Mycetoma	7.3%
186	Cartilage Diseases	7.3%
187	Rheumatism	7.3%
188	Chondromalacia	7.3%
189	Acute Generalized Exanthematous Pustulosis	7.3%
190	Lupus Erythematosus, Systemic	7%
191	Overlap syndrome	7%
192	Scleromyxedema	6.7%
193	Leishmaniasis, Cutaneous	6.1%
194	Eczema Herpeticum	6.1%
195	Warts	6.1%
196	Fusariosis	6%
197	Candidiasis, Chronic Mucocutaneous	5.9%
198	Cutaneous Candidiasis	5.9%
199	Erysipelas	5.9%
200	Serum Sickness	5.9%
201	Staphylococcal Skin Infections	5.9%
202	Variegate Porphyria	5.9%
203	Acute intermittent porphyria	5.9%
204	Porphyria Cutanea Tarda	5.9%
205	Erythrasma	5.9%
206	Carcinoma, Lobular	5.9%
207	Arthritis, Psoriatic	5.8%
208	CREST Syndrome	5.6%
209	Hereditary Angioedema Type III	5.4%
210	Hereditary Angioedema Types I and II	5.4%
211	Dupuytren Contracture	5%
212	Angioedemas, Hereditary	5%
213	Epidermodysplasia Verruciformis	4.9%
214	Herpes Labialis	4.9%
215	Hidradenitis Suppurativa	4.9%
216	Giant Cell Arteritis	4.9%
217	Temporal Arteritis	4.9%
218	Diabetic Foot	4.9%
219	Staphylococcal Scalded Skin Syndrome	4.8%
220	Mesenteric Panniculitis	4.5%
221	Panniculitis, Peritoneal	4.5%
222	Tietze's Syndrome	4.5%
223	Orbital Cellulitis	4.5%
224	Myxoid cyst	4.5%
225	Peutz-Jeghers Syndrome	4.5%
226	Myxedema	4.4%
227	carbuncle	4.3%
228	Blastomycosis	4.2%
229	HIV-Associated Lipodystrophy Syndrome	4.2%
230	Condylomata Acuminata	4.1%
231	Furunculosis	4.1%
232	furuncle	4.1%
233	Cellulitis	4%
234	Impetigo	4%
235	Rhinoscleroma	3.8%
236	Menkes Kinky Hair Syndrome	3.5%
237	Osteochondritis	3.4%
238	Polymyalgia Rheumatica	3.4%
239	Osteogenesis Imperfecta	3.4%
240	Keloid	3.3%
241	Noonan Syndrome	2.9%
242	Rheumatoid Arthritis	2.7%
243	Juvenile arthritis	2.7%
244	Lupus Nephritis	2.6%
245	Marfan Syndrome	2.5%
246	Rheumatoid Nodule	2.5%
247	Homocystinuria	2.4%
248	Laryngomalacia	2.3%
249	Pectus carinatum	2.3%
250	Felty Syndrome	2%
251	Bronchomalacia	2%
252	Tracheomalacia	2%
253	Rheumatoid Vasculitis	1.6%
254	Mucopolysaccharidosis III	1.6%
255	Sicca Syndrome	1.4%
256	Sjogren's Syndrome	1.4%
257	Lupus Vasculitis, Central Nervous System	1.1%
258	Mucopolysaccharidosis II	1.1%

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