MetaADEDB 2.0 @ LMMD
Rosacea
(UMLS:C0035854)
Definition:
A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).
UMLS ID:
C0035854
MeSH ID:
D012393
Classification:
Name:
Skin and Connective Tissue Diseases
MeSH Tree Number(s):
C17.800.716
Synonym(s)
1.
Rosacea
2.
ACNE ROSACEA
3.
Acne Rosacea
4.
Acne erythematosa
5.
Acne rosacea
6.
Acne;rosacea
7.
ROSACEA
8.
Rosacea, unspecified
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1Azelaic acidFAERS: 53

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17472690
17500380
18561584
18803456
19363903
19588640
20545756
20645521
20967185
21916272
22111946
 		CTD
US FAERS
2Fingolimod HydrochlorideFAERS: 35
Canada Vigilance: 1		Canada Vigilance
US FAERS
3MetronidazoleFAERS: 27
Canada Vigilance: 8

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9645635
17244346
17500380
20645521
20967185
 		CTD
SIDER
Canada Vigilance
US FAERS
4AlendronateFAERS: 22US FAERS
5Dimethyl FumarateFAERS: 20US FAERS
6tofacitinibFAERS: 18
Canada Vigilance: 2		Canada Vigilance
US FAERS
7NorgestrelFAERS: 17US FAERS
8IsotretinoinFAERS: 1511763399CTD
US FAERS
9OxymetazolineFAERS: 15US FAERS
10NuvaRingFAERS: 12US FAERS
11TeriparatideFAERS: 11US FAERS
12LisinoprilFAERS: 8US FAERS
13apremilastFAERS: 8US FAERS
14rofecoxibFAERS: 8US FAERS
15Erlotinib HydrochlorideFAERS: 7US FAERS
16FinasterideFAERS: 7US FAERS
17LenalidomideFAERS: 7US FAERS
18ambrisentanFAERS: 6US FAERS
19AN2728FAERS: 5US FAERS
20AtorvastatinFAERS: 5US FAERS
21DoxycyclineFAERS: 519588640
20645521
21916272		CTD
US FAERS
22DoxycyclineFAERS: 5US FAERS
23ThyroxineFAERS: 5US FAERS
24DabigatranFAERS: 4US FAERS
25Medroxyprogesterone AcetateFAERS: 44261461CTD
US FAERS
26PCI 32765FAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
27PregabalinFAERS: 4US FAERS
28RivaroxabanFAERS: 4US FAERS
29TacrolimusFAERS: 415096374CTD
SIDER
US FAERS
30TadalafilFAERS: 4US FAERS
31Tiotropium BromideFAERS: 4US FAERS
32Venlafaxine HydrochlorideFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
33mirabegronFAERS: 4US FAERS
34pimecrolimusFAERS: 4

View details

12920379
16488319
17373975
17910727
 		CTD
US FAERS
354-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 3US FAERS
36BimatoprostFAERS: 3US FAERS
37DiclofenacFAERS: 3US FAERS
38FluticasoneFAERS: 3US FAERS
39Glatiramer AcetateFAERS: 3US FAERS
40LiraglutideFAERS: 3US FAERS
41MinocyclineFAERS: 317910727CTD
US FAERS
42NiacinFAERS: 3US FAERS
43OmeprazoleFAERS: 3US FAERS
44Ortho EvraFAERS: 3US FAERS
45RestasisFAERS: 3US FAERS
46Ruxolitinib phosphateFAERS: 3US FAERS
47Sildenafil CitrateFAERS: 3US FAERS
48Sitagliptin PhosphateFAERS: 3US FAERS
49ThyroxineFAERS: 3US FAERS
50ValsartanFAERS: 3US FAERS
51candesartan cilexetilFAERS: 3US FAERS
52treprostinilFAERS: 3US FAERS
532-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chlorideFAERS: 2US FAERS
543-ingenyl angelateFAERS: 2US FAERS
554-AminopyridineFAERS: 2US FAERS
56Advil PMFAERS: 2US FAERS
57AmlodipineFAERS: 2US FAERS
58AmlodipineFAERS: 2US FAERS
59BosentanFAERS: 2US FAERS
60CID 129626832FAERS: 2US FAERS
61DapsoneFAERS: 2US FAERS
62DronedaroneFAERS: 2US FAERS
63DroxidopaFAERS: 2US FAERS
64Duloxetine HydrochlorideFAERS: 2US FAERS
65ExenatideFAERS: 2US FAERS
66EzetimibeFAERS: 2US FAERS
67Imatinib MesylateFAERS: 2US FAERS
68ImiquimodFAERS: 2US FAERS
69KetoconazoleFAERS: 2US FAERS
70LamotrigineFAERS: 2US FAERS
71MethotrexateFAERS: 2US FAERS
72MethotrexateFAERS: 2US FAERS
73MinocyclineFAERS: 2US FAERS
74NorethindroneFAERS: 2US FAERS
75OseltamivirFAERS: 2US FAERS
76PropranololFAERS: 2US FAERS
77Quetiapine FumarateFAERS: 2US FAERS
78VareniclineFAERS: 2US FAERS
79WarfarinFAERS: 2US FAERS
80betamethasone dipropionate, calcipotriol drug combinationFAERS: 2US FAERS
81betamethasone-17,21-dipropionateFAERS: 2US FAERS
82fluticasone furoateFAERS: 2US FAERS
83pirfenidoneFAERS: 2US FAERS
84teriflunomideFAERS: 2US FAERS
85valdecoxibFAERS: 2US FAERS
864-hydroxybutyric acidFAERS: 1US FAERS
875-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzimidazol-5-yl)pyrimidin-2-yl)amineFAERS: 1US FAERS
887-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3-carbonitrileFAERS: 1US FAERS
89AcitretinFAERS: 1US FAERS
90AfatinibFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
91AmoxicillinFAERS: 1US FAERS
92AripiprazoleFAERS: 1SIDER
US FAERS
93Atomoxetine HydrochlorideFAERS: 1US FAERS
94Betamethasone ValerateFAERS: 14231359CTD
US FAERS
95Breo ElliptaFAERS: 1US FAERS
96CelecoxibFAERS: 1US FAERS
97CetirizineFAERS: 1US FAERS
98CiprofloxacinFAERS: 1US FAERS
99Clindamycin phosphate and tretinoinFAERS: 1US FAERS
100ClindamycinFAERS: 1US FAERS
101ClobetasolFAERS: 1US FAERS
102ClonazepamFAERS: 1US FAERS
103ClonidineFAERS: 1US FAERS
104CopperFAERS: 1US FAERS
105Desvenlafaxine SuccinateFAERS: 1US FAERS
106Diovan HctFAERS: 1US FAERS
107DoxorubicinFAERS: 1US FAERS
108ErythromycinFAERS: 1US FAERS
109EsomeprazoleFAERS: 1US FAERS
110Ethylene GlycolFAERS: 1US FAERS
111EverolimusFAERS: 1US FAERS
112FS 069FAERS: 1US FAERS
113FebuxostatFAERS: 1US FAERS
114Fexofenadine hydrochloride and pseudoephedrine hydrochlorideFAERS: 1US FAERS
115FluoxetineFAERS: 1US FAERS
116FluoxetineFAERS: 1US FAERS
117GefitinibFAERS: 1US FAERS
118GemifloxacinFAERS: 1US FAERS
119HhAntag691FAERS: 1US FAERS
120HydrochlorothiazideFAERS: 1US FAERS
121Ibandronic AcidFAERS: 1US FAERS
122IrbesartanFAERS: 1US FAERS
123ItraconazoleFAERS: 1US FAERS
124IvosidenibFAERS: 1US FAERS
125KetoconazoleFAERS: 1US FAERS
126LeuprolideFAERS: 1US FAERS
127LevetiracetamFAERS: 1US FAERS
128LoratadineFAERS: 1US FAERS
129LorazepamFAERS: 1US FAERS
130LosartanFAERS: 1US FAERS
131MetforminFAERS: 1US FAERS
132MethadoneFAERS: 1US FAERS
133MethylphenidateFAERS: 1US FAERS
134MidodrineFAERS: 1US FAERS
135MirtazapineFAERS: 1US FAERS
136ModafinilFAERS: 1US FAERS
137NicotineFAERS: 1US FAERS
138OlanzapineFAERS: 1US FAERS
139OmacorFAERS: 1US FAERS
140OndansetronFAERS: 1US FAERS
141OrlistatFAERS: 1US FAERS
142OspemifeneFAERS: 1US FAERS
143ParoxetineFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
144PentazocineFAERS: 1US FAERS
145PerindoprilFAERS: 1US FAERS
146PrednisoloneFAERS: 1US FAERS
147ProgesteroneFAERS: 1US FAERS
148Quetiapine FumarateFAERS: 1US FAERS
149RamiprilFAERS: 1US FAERS
150RifaximinFAERS: 1US FAERS
151RisperidoneFAERS: 1US FAERS
152Rosuvastatin CalciumFAERS: 1US FAERS
153Rosuvastatin CalciumFAERS: 1US FAERS
154SimvastatinFAERS: 1US FAERS
155SofosbuvirFAERS: 1US FAERS
156SunitinibFAERS: 1US FAERS
157TamsulosinFAERS: 1US FAERS
158TelmisartanFAERS: 1US FAERS
159TestosteroneFAERS: 1SIDER
US FAERS
160TetracyclineFAERS: 1128376
9645635		CTD
US FAERS
161Tolterodine TartrateFAERS: 1US FAERS
162TopiramateFAERS: 1US FAERS
163TretinoinFAERS: 1US FAERS
164ValacyclovirFAERS: 1US FAERS
165WarfarinFAERS: 1US FAERS
166Zoledronic AcidFAERS: 1US FAERS
167aclidinium bromideFAERS: 1US FAERS
168alfuzosinFAERS: 1US FAERS
169apixabanFAERS: 1US FAERS
170cefprozilFAERS: 1US FAERS
171dolutegravirFAERS: 1US FAERS
172efinaconazoleFAERS: 1US FAERS
173elagolixFAERS: 1US FAERS
174eltrombopagFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
175eluxadolineFAERS: 1US FAERS
176empagliflozinFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
177exemestaneFAERS: 1US FAERS
178gadobutrolFAERS: 1US FAERS
179ledipasvir, sofosbuvir drug combinationFAERS: 1US FAERS
180lifitegrastFAERS: 1US FAERS
181oxybutyninFAERS: 1US FAERS
182palbociclibFAERS: 1US FAERS
183ribociclibFAERS: 1US FAERS
184tegaserodFAERS: 1US FAERS
185Acetazolamide8251374CTD
186Amiodarone2952013CTD
187Azithromycin17244346CTD
188Beclomethasone10192164CTD
189Brimonidine TartrateSIDER
190CapecitabineSIDER
191Clarithromycin19207666CTD
192Clindamycin2521597CTD
193ClobetasolSIDER
194ClobetasoneSIDER
195DoxepinSIDER
196Erlotinib HydrochlorideSIDER
197EtoricoxibSIDER
198Etretinate6183905CTD
199Hydrocortisone4237682
16384783		CTD
SIDER
200Ivermectin28653460CTD
201LasofoxifeneSIDER
202LetrozoleCanada Vigilance: 1Canada Vigilance
203Methylprednisolone11763399CTD
204Mometasone FuroateSIDER
205Niacinamide18189062CTD
206PramipexoleSIDER
207PrednisoneSIDER
208Ribavirin14558405
16710591		CTD
209Risedronic AcidCanada Vigilance: 1Canada Vigilance
210TramadolSIDER
211TriamcinoloneSIDER
212Vitamin B 1211763399CTD
213Vitamin B 611763399CTD
214amineptin2977084CTD
215cevimelineSIDER
216rescinnamineSIDER
217sitaxsentanSIDER
Similar ADE(s)
NameSemantic Similarity
1Pyoderma Gangrenosum45.8%
2Breast Diseases42.9%
3Dermatitis42.9%
4Exanthema42.9%
5Facial Dermatoses42.9%
6Hair Diseases42.9%
7Hand Dermatoses42.9%
8keratoacanthoma42.9%
9Keratosis42.9%
10Nail Diseases42.9%
11Photosensitivity Disorders42.9%
12Prurigo42.9%
13Pyoderma42.9%
14Sebaceous Gland Diseases42.9%
15Skin Diseases, Vesiculobullous42.9%
16Skin Ulcer42.9%
17Sweat Gland Diseases42.9%
18Skin Diseases, Papulosquamous42.9%
19Skin Diseases, Vascular42.9%
20Acneiform Eruptions42.9%
21Subcorneal pustular dermatosis42.9%
22Chronic Actinic Dermatitis42.9%
23Acne Vulgaris40.9%
24Contact Dermatitis40.9%
25Eczema40.9%
26Erythema Multiforme40.9%
27Intertrigo40.9%
28Neurodermatitis40.9%
29Perioral Dermatitis40.9%
30Acne40.9%
31Lupus Erythematosus, Cutaneous38.1%
32Panniculitis38.1%
33Systemic Scleroderma38.1%
34Morphea38.1%
35Dermatitis, Phototoxic37.2%
36Pityriasis Lichenoides et Varioliformis Acuta37.2%
37Pityriasis Lichenoides37.2%
38Phototoxicity37.2%
39Foot Ulcer37.1%
40Dermatitis, Irritant33.3%
41Acne Conglobata33.3%
42Anhidrosis31%
43Cholesteatoma31%
44Pressure Ulcer31%
45Dermatitis Herpetiformis31%
46Folliculitis31%
47Foot Dermatoses31%
48Gynecomastia31%
49Hypertrichosis31%
50Hypohidrosis31%
51Hypotrichosis31%
52Leg Ulcer31%
53Miliaria31%
54Parakeratosis31%
55Parapsoriasis31%
56Pityriasis31%
57Psoriasis31%
58Sweet Syndrome31%
59Hidradenitis31%
60Onycholysis31%
61Miliaria Rubra31%
62Hyperpigmentation31%
63Lichenoid Eruptions31%
64Chloracne31%
65Acrodermatitis30.5%
66Sebaceous Gland Neoplasms30.5%
67Porokeratosis30.5%
68Gianotti-Crosti Syndrome30.5%
69Keratoderma, Palmoplantar30.5%
70Dermatitis, Atopic30.3%
71Epidermolysis Bullosa30.3%
72Foot Diseases30%
73Diaper Rash29.7%
74Dermatitis, Photoallergic29.6%
75Panniculitis, Lupus Erythematosus29.3%
76Skin Abnormalities28.6%
77Skin Diseases, Infectious28.6%
78Skin Neoplasms28.6%
79Pigmentation Disorders28.6%
80Lipomatosis27.9%
81Pruritus27.9%
82Erythema27.9%
83Necrolytic Migratory Erythema27.9%
84Cutaneous Fistula27.9%
85Nephrogenic Fibrosing Dermopathy27.9%
86Nephrogenic Systemic Fibrosis27.9%
87Necrobiosis Lipoidica Diabeticorum27.5%
88Urticaria Pigmentosa27.3%
89Lupus Erythematosus, Discoid27.3%
90Scleroderma, Limited27.3%
91Xeroderma Pigmentosum27.1%
92Dermatitis, Occupational26.3%
93Lichen Planus25.4%
94Melanosis25.4%
95Chloasma25.4%
96Pityriasis Rosea25.4%
97Pityriasis Rubra Pilaris25.4%
98Vitiligo25.4%
99Lichen Nitidus25.4%
100Dermatitis, Allergic Contact25%
101Papillon-Lefevre Disease24.8%
102Xeroderma24.7%
103Connective Tissue Diseases23.1%
104Erythema Induratum22.8%
105Acanthosis Nigricans22.7%
106Alopecia Areata22.7%
107Lentigo22.7%
108Erythema Infectiosum22.4%
109Cutis Laxa22.4%
110Exanthema Subitum22.3%
111Erythema Nodosum21.9%
112Dermatomyositis21.8%
113Toxic Epidermal Necrolysis21.1%
114Stevens-Johnson Syndrome21.1%
115Acantholysis20.9%
116Breast Cyst20.9%
117Actinic keratosis20.9%
118Pemphigoid, Benign Mucous Membrane20.9%
119Pemphigus20.9%
120Piedra20.9%
121Sunburn20.9%
122Tinea Capitis20.7%
123Onychomycosis20.7%
124Mastocytosis20.5%
125Argyria20.5%
126Hirsutism20.5%
127Lactation Disorder20.5%
128Mastitis20.5%
129Rhinophyma20.5%
130Urticaria20.5%
131Adiposis Dolorosa20.2%
132Ectodermal Dysplasia20.2%
133Pruritus Vulvae20.2%
134Aplasia Cutis Congenita20.2%
135Mastocytoma20.1%
136Pruritus Ani20.1%
137Hyperkeratosis, Epidermolytic19.5%
138Granuloma Annulare19.3%
139Pseudoxanthoma Elasticum18.6%
140Ecthyma18.2%
141Alopecia17.2%
142Sweating, Gustatory17.2%
143Androgenetic Alopecia17.2%
144Auriculotemporal Syndrome17.2%
145Lice Infestations16.9%
146Varicose Ulcer16.9%
147Breast Neoplasms, Male16.9%
148Triple Negative Breast Neoplasms16.9%
149Galactorrhea16.7%
150Hidradenitis Suppurativa16.6%
151Ichthyosis, X-Linked15.8%
152Behcet Syndrome15.8%
153Sjogren-Larsson Syndrome15.7%
154Dermatomycoses15.5%
155Mucocutaneous Lymph Node Syndrome15.5%
156Skin Diseases, Bacterial15.5%
157Tinea Pedis15.5%
158Lichen Planus, Oral15.4%
159Drug Eruptions15.3%
160Lipodystrophy15.3%
161Livedo Reticularis15.3%
162Malignant Atrophic Papulosis15.3%
163Polyarteritis Nodosa15%
164Takayasu Arteritis15%
165Collagen Diseases14.3%
166Mixed Connective Tissue Disease14.3%
167Mucinoses14.3%
168Albinism13.8%
169Erythema Chronicum Migrans13.5%
170Larva Migrans12.8%
171Leishmaniasis12.8%
172Molluscum Contagiosum12.8%
173Angioedema12.7%
174Onchocerciasis12.6%
175Chromoblastomycosis12.5%
176Dermatophytosis12.5%
177Nail-Patella Syndrome12.5%
178Sporotrichosis12.5%
179Tinea12.5%
180Tinea Versicolor12.5%
181Trichophytosis12.5%
182Hyalohyphomycosis12.5%
183Acute Generalized Exanthematous Pustulosis12.4%
184Porphyrias, Hepatic12.3%
185Mycetoma12.3%
186Leishmaniasis, Cutaneous11.2%
187Eczema Herpeticum11.2%
188Fusariosis11.1%
189Hereditary Angioedema Type III10.4%
190Hereditary Angioedema Types I and II10.4%
191Scleromyxedema10.3%
192Warts10.3%
193Candidiasis, Chronic Mucocutaneous10%
194Cutaneous Candidiasis10%
195Cartilage Diseases10%
196Rheumatism10%
197Chondromalacia10%
198Erysipelas9.9%
199Serum Sickness9.9%
200Staphylococcal Skin Infections9.9%
201Variegate Porphyria9.9%
202Acute intermittent porphyria9.9%
203Porphyria Cutanea Tarda9.9%
204Erythrasma9.9%
205Carcinoma, Lobular9.9%
206Arthritis, Psoriatic9.9%
207Lupus Erythematosus, Systemic9.5%
208Overlap syndrome9.5%
209CREST Syndrome9.4%
210Angioedemas, Hereditary9.1%
211Epidermodysplasia Verruciformis9%
212Herpes Labialis9%
213Diabetic Foot8.9%
214Staphylococcal Scalded Skin Syndrome8.8%
215Peutz-Jeghers Syndrome8.6%
216carbuncle8.2%
217Condylomata Acuminata7.5%
218Furunculosis7.4%
219furuncle7.4%
220Giant Cell Arteritis7.4%
221Temporal Arteritis7.4%
222Impetigo7.3%
223Blastomycosis7.1%
224HIV-Associated Lipodystrophy Syndrome7%
225Mesenteric Panniculitis7%
226Panniculitis, Peritoneal7%
227Tietze's Syndrome7%
228Orbital Cellulitis7%
229Myxoid cyst7%
230Myxedema6.8%
231Dupuytren Contracture6.8%
232Rhinoscleroma6.4%
233Cellulitis5.4%
234Menkes Kinky Hair Syndrome5.3%
235Osteochondritis5.3%
236Polymyalgia Rheumatica5.3%
237Osteogenesis Imperfecta5.1%
238Keloid5%
239Rheumatoid Arthritis4.2%
240Rheumatoid Nodule4.2%
241Juvenile arthritis4.2%
242Lupus Nephritis4%
243Noonan Syndrome3.8%
244Laryngomalacia3.5%
245Pectus carinatum3.4%
246Marfan Syndrome3.4%
247Felty Syndrome3.3%
248Bronchomalacia3.3%
249Tracheomalacia3.3%
250Homocystinuria3.3%
251Rheumatoid Vasculitis2.8%
252Mucopolysaccharidosis III2.7%
253Sicca Syndrome2.4%
254Sjogren's Syndrome2.4%
255Mucopolysaccharidosis II1.8%
256Lupus Vasculitis, Central Nervous System1.6%
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