MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Environmental Illness

(UMLS:C0282504)

Definition:: A polysymptomatic condition believed by clinical ecologists to result from immune dysregulation induced by common foods, allergens, and chemicals, resulting in various physical and mental disorders. The medical community has remained largely skeptical of the existence of this "disease", given the plethora of symptoms attributed to environmental illness, the lack of reproducible laboratory abnormalities, and the use of unproven therapies to treat the condition. (From Segen, Dictionary of Modern Medicine, 1992)
UMLS ID:: C0282504
MeSH ID:: D018876

Classification 1:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.312

Classification 2:

Name:

Disorders of Environmental Origin
MeSH Tree Number(s):: C21.223

Synonym(s)

Environmental Illness

ENVIRONMENTAL ALLERGIES

Environmental Allergy

Environmental allergy

environmental allergies

environmental allergy

environmental illness

environmental illnesses

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	chromium hexavalent ion		25342458	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Immune Complex Diseases	30%
2	Latex allergy	30%
3	anaphylaxis	22%
4	Food Allergy	22%
5	Anaphylactic shock	22%
6	Serum Sickness	18.9%
7	Milk Allergy	18.1%
8	Wheat Hypersensitivity	18.1%
9	Asthma, Aspirin-Induced	17.8%
10	Kounis Syndrome	17.1%
11	Respiratory Hypersensitivity	17%
12	Urticaria	16.1%
13	Vasculitis, Leukocytoclastic, Cutaneous	16.1%
14	Autoimmune Diseases	15.8%
15	Immunologic Deficiency Syndromes	15.8%
16	Immunoproliferative Disorders	15.8%
17	Immune reconstitution syndrome	15.8%
18	Immune Reconstitution Inflammatory Syndrome	15.8%
19	Mastocytosis, Systemic	13.1%
20	Mastocytosis	12.8%
21	Drug Eruptions	12.7%
22	Dermatitis, Allergic Contact	12.5%
23	Transfusion Reaction	11.5%
24	Hypotensive Transfusion Reaction	11.5%
25	Angioedema	10.6%
26	Acute Generalized Exanthematous Pustulosis	10.3%
27	Antiphospholipid Syndrome	10%
28	Asthma, Exercise-Induced	9.4%
29	Status Asthmaticus	9.4%
30	Dermatitis, Atopic	8.9%
31	Asthma	8.9%
32	Hereditary Angioedema Type III	8.7%
33	Hereditary Angioedema Types I and II	8.7%
34	Glomerulonephritis, Membranoproliferative	8.6%
35	Erythema Nodosum	8.6%
36	Dermatitis, Photoallergic	8.5%
37	Autoimmune Lymphoproliferative Syndrome	8.3%
38	Asthma, Occupational	8.1%
39	Farmer's Lung	7.8%
40	Angioedemas, Hereditary	7.8%
41	Hay fever	7.7%
42	Rhinitis, Allergic, Perennial	7.7%
43	Lupus Erythematosus, Systemic	7.4%
44	Lymphoproliferative Disorders	7.4%
45	Overlap syndrome	7.4%
46	Aspergillosis, Allergic Bronchopulmonary	7.4%
47	Addison Disease	7.3%
48	Paraproteinemias	7.3%
49	Pemphigus	7.3%
50	Autoimmune thyroiditis	7.3%
51	Primary Adrenal Insufficiency	7.3%
52	Lymphopenia	7.2%
53	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.2%
54	Autoimmune hepatitis	7.2%
55	Primary amyloidosis	6.9%
56	Monoclonal Gammopathy of Undetermined Significance	6.9%
57	Toxic Epidermal Necrolysis	6.3%
58	Stevens-Johnson Syndrome	6.3%
59	Autoimmune thrombocytopenia	6.1%
60	Immune thrombocytopenic purpura	6.1%
61	Schnitzler Syndrome	6%
62	Thrombocytopenic purpura	6%
63	Hypergammaglobulinemia	5.8%
64	Latent Autoimmune Diabetes in Adults	5.8%
65	Agammaglobulinemia	5.7%
66	Dermatitis Herpetiformis	5.7%
67	HIV Infections	5.7%
68	Transfusion-Related Acute Lung Injury	5.7%
69	Plasmacytoma	5.4%
70	Tumor Lysis Syndrome	5.4%
71	HTLV-I Infections	5.3%
72	Job Syndrome	5.3%
73	Multiple Myeloma	5.1%
74	Sezary Syndrome	4.9%
75	Rheumatoid Arthritis	4.8%
76	Juvenile arthritis	4.8%
77	Graves Disease	4.7%
78	Anti-Glomerular Basement Membrane Disease	4.6%
79	Lymphoma	4.3%
80	Myasthenia Gravis	4.3%
81	Uveomeningoencephalitic Syndrome	4.3%
82	Myasthenia Gravis, Autoimmune, Experimental	4.2%
83	Chronic granulomatous disease	4.2%
84	Heavy Chain Disease	4.2%
85	Granulomatosis with polyangiitis	4.2%
86	HIV Seropositivity	4.2%
87	Stiff-Person Syndrome	3.6%
88	Polyradiculoneuropathy	3.6%
89	Polyradiculoneuritis	3.6%
90	Multiple Sclerosis	3.5%
91	Acquired Immunodeficiency Syndrome	3.5%
92	AIDS related complex	3.5%
93	Hodgkin Disease	3.5%
94	Leukemia, Plasma Cell	3.5%
95	Lymphoma, Non-Hodgkin	3.5%
96	Infectious Mononucleosis	3.5%
97	Kernicterus	3.5%
98	Cryoglobulinemia	3.4%
99	Felty Syndrome	3.4%
100	Leukemia, T-Cell	3.4%
101	POEMS Syndrome	3.4%
102	Leukemia, B-Cell	3.4%
103	Lupus Nephritis	3.4%
104	Neuromyelitis Optica	3.2%
105	Leukoencephalitis, Acute Hemorrhagic	3.2%
106	Multiple Sclerosis, Chronic Progressive	3.1%
107	Multiple Sclerosis, Relapsing-Remitting	3.1%
108	Ataxia Telangiectasia	3.1%
109	Lymphoma, Follicular	3.1%
110	T-Cell Lymphoma	3.1%
111	Mantle cell lymphoma	3.1%
112	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.1%
113	Leukemia, Large Granular Lymphocytic	3.1%
114	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.1%
115	Hydrops Fetalis	3%
116	AIDS-Related Opportunistic Infections	3%
117	Vasculitis, Central Nervous System	3%
118	HIV Wasting Syndrome	2.9%
119	Rheumatoid Vasculitis	2.9%
120	AIDS Dementia Complex	2.9%
121	AIDS-Associated Nephropathy	2.9%
122	Lymphoma, T-Cell, Cutaneous	2.9%
123	Lymphoma, AIDS-Related	2.9%
124	Enteropathy-Associated T-Cell Lymphoma	2.9%
125	Primary Effusion Lymphoma	2.9%
126	Composite Lymphoma	2.9%
127	Encephalomyelitis, Acute Disseminated	2.9%
128	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.9%
129	Neuritis, Autoimmune, Experimental	2.9%
130	Lymphangioleiomyomatosis	2.8%
131	Lupus Vasculitis, Central Nervous System	2.8%
132	Mycosis Fungoides	2.8%
133	Lymphomatoid Papulosis	2.8%
134	Plasmablastic lymphoma	2.8%
135	Lambert-Eaton Myasthenic Syndrome	2.6%
136	Waldenstrom Macroglobulinemia	2.6%
137	Wiskott-Aldrich Syndrome	2.6%
138	Sicca Syndrome	2.6%
139	Sjogren's Syndrome	2.6%
140	HIV-Associated Lipodystrophy Syndrome	2.5%
141	Guillain-Barre Syndrome	2.4%
142	Lymphomatoid Granulomatosis	2.4%
143	Burkitt Lymphoma	2%
144	Giant Cell Arteritis	1.9%
145	Temporal Arteritis	1.9%
146	Myelitis, Transverse	1.7%
147	Miller Fisher Syndrome	1.5%

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