MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Rhinitis, Allergic, Perennial

(UMLS:C0035457)

Definition:: Inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year. The causes are usually air-borne allergens, particularly dusts, feathers, molds, animal fur, etc.
UMLS ID:: C0035457
MeSH ID:: D012221

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.460.799.315.500|C08.674.453.500

Classification 2:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.603.799.315.500

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.480.680.443.500

Synonym(s)

Rhinitis, Allergic, Perennial

Non-seasonal Allergic Rhinitis

Non-seasonal allergic rhinitis

Nonseasonal allergic rhinitis

Perennial Allergic Rhinitis

Perennial allergic rhinitis

allergic rhinitis perennial

allergic; rhinitis, nonseasonal

atopic rhinitis

10.

perennial allergic rhinitis

11.

rhinitis; allergic, nonseasonal

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Astemizole	View details 1283658 2476015 2861220 10822083	CTD
2	Beclomethasone	2861220 18422164 19233485	CTD
3	Cetirizine	9934406 11034010 20375960	CTD
4	Chlorpheniramine	8201490 10822083	CTD
5	Fluticasone	9934406	CTD
6	Ketotifen	10822083	CTD
7	Loratadine	15119752	CTD
8	Mometasone Furoate	19233485	CTD
9	Ozone	19389874	CTD
10	Phenylpropanolamine	4163280	CTD
11	Pseudoephedrine	15119752	CTD
12	Terfenadine	2476015 8201490	CTD
13	Toluene 2,4-Diisocyanate	12617775 15015336	CTD
14	azatadine	2476015	CTD
15	epinastine	10822083 15119752	CTD
16	gamma-Tocopherol	19389874	CTD
17	mequitazine	2476015	CTD
18	mizolastine	18020585	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hay fever	50.6%
2	Asthma	26.4%
3	Rhinitis, Vasomotor	25.1%
4	Aspergillosis, Allergic Bronchopulmonary	20.9%
5	Granuloma, Lethal Midline	20.1%
6	Nose Deformities, Acquired	20.1%
7	Choanal Atresia	19.8%
8	Asthma, Exercise-Induced	17.2%
9	Status Asthmaticus	17.2%
10	Asthma, Aspirin-Induced	17.2%
11	Nasal Polyps	17.2%
12	Laryngeal Diseases	16.3%
13	Paranasal Sinus Neoplasms	16.1%
14	Nose Neoplasms	15.8%
15	Sinusitis	15.6%
16	Asthma, Occupational	15.5%
17	Epistaxis	15%
18	Farmer's Lung	14.3%
19	Rhinoscleroma	14.2%
20	Tracheobronchomegaly	13.9%
21	Bronchitis	13.8%
22	Laryngitis	13%
23	Vocal Cord Dysfunction	13%
24	Bronchial Diseases	12.9%
25	Lung diseases	12.9%
26	Pleural Diseases	12.9%
27	Respiration Disorders	12.9%
28	Thoracic Diseases	12.9%
29	Tracheal Diseases	12.9%
30	Granuloma, Laryngeal	12.7%
31	Pleurisy	12.3%
32	Pneumonia	12.3%
33	Lobar Pneumonia	12.3%
34	Respiratory Distress Syndrome, Adult	12.3%
35	Tracheitis	12.3%
36	Pneumonitis	12.3%
37	Primary Ciliary Dyskinesia	12%
38	Laryngeal neoplasm	12%
39	Bronchopneumonia	11.8%
40	Pleuropneumonia	11.5%
41	anaphylaxis	11.4%
42	Food Allergy	11.4%
43	Anaphylactic shock	11.4%
44	Laryngocele	11.4%
45	Maxillary Sinus Neoplasms	10.8%
46	Respiratory Tract Infections	10.8%
47	Granuloma, Respiratory Tract	10.7%
48	Respiratory Tract Fistula	10.7%
49	Lung Diseases, Fungal	10.6%
50	Respiratory Distress Syndrome, Newborn	10.5%
51	Bronchial Fistula	10.5%
52	Lung Abscess	10.5%
53	Lung Neoplasms	10.5%
54	Pleural Neoplasms	10.5%
55	Tuberculosis, Pulmonary	10.4%
56	Bronchitis, Chronic	9.8%
57	Urticaria	9.5%
58	Tracheal Neoplasms	9.1%
59	Laryngeal Edema	8.9%
60	Immune Complex Diseases	8.9%
61	Latex allergy	8.9%
62	Bronchiolitis	8.9%
63	Pleural Effusion, Malignant	8.6%
64	Bronchial Neoplasms	8.5%
65	Rhinitis	8.2%
66	Laryngospasm	8%
67	Pharyngitis	7.7%
68	Environmental Illness	7.7%
69	Laryngostenosis	7.6%
70	Aspiration Pneumonia	7.6%
71	Scimitar Syndrome	7.4%
72	Altitude Sickness	7.3%
73	Atelectasis	7.3%
74	Bronchospasm	7.3%
75	Bronchiectasis	7.3%
76	Chylothorax	7.3%
77	Hydropneumothorax	7.3%
78	Hydrothorax	7.3%
79	Pulmonary Hypertension	7.3%
80	Pneumothorax	7.3%
81	Pulmonary Alveolar Proteinosis	7.3%
82	Pulmonary Edema	7.3%
83	Pulmonary Fibrosis	7.3%
84	Respiratory Insufficiency	7.3%
85	Tracheal Stenosis	7.3%
86	Bronchial Hyperreactivity	7.3%
87	Hamman-Rich syndrome	7.3%
88	Lung Diseases, Interstitial	7.3%
89	Respiratory Depression	7.3%
90	Lung Diseases, Obstructive	7.3%
91	Respiratory Failure	7.3%
92	Acute Chest Syndrome	7.2%
93	Kartagener Syndrome	7%
94	Hoarseness	6.9%
95	Milk Allergy	6.8%
96	Wheat Hypersensitivity	6.8%
97	Pneumoconiosis	6.7%
98	Pneumonia, Viral	6.7%
99	Voice Disorders	6.7%
100	Voice Disturbance	6.7%
101	Meconium Aspiration Syndrome	6.7%
102	Pneumonia, Bacterial	6.6%
103	Hyaline Membrane Disease	6.5%
104	Multiple Pulmonary Nodules	6.5%
105	Idiopathic Pulmonary Fibrosis	6.5%
106	Dermatitis, Atopic	6.4%
107	Kounis Syndrome	6.4%
108	Lung Injury	6.1%
109	Hepatopulmonary Syndrome	6.1%
110	Respiratory Aspiration	6.1%
111	Ear Diseases	6.1%
112	Apnea	6.1%
113	Cheyne-Stokes Respiration	6.1%
114	Common Cold	6.1%
115	Dyspnea	6.1%
116	Hemothorax	6.1%
117	Hyperventilation	6.1%
118	Influenza	6.1%
119	Mouth Breathing	6.1%
120	Tachypnea	6.1%
121	Catarrh	6.1%
122	Pulmonary Embolism	6%
123	Pulmonary Eosinophilia	6%
124	Severe Acute Respiratory Syndrome	6%
125	Eosinophilic Pneumonia	6%
126	Laryngopharyngeal Reflux	6%
127	Laryngomalacia	6%
128	Vocal Cord Paralysis	5.9%
129	Nose Diseases	5.8%
130	Radiation Pneumonitis	5.8%
131	Radiation Fibrosis	5.8%
132	Autoimmune Diseases	5.8%
133	Immunologic Deficiency Syndromes	5.8%
134	Immunoproliferative Disorders	5.8%
135	Immune reconstitution syndrome	5.8%
136	Immune Reconstitution Inflammatory Syndrome	5.8%
137	Croup	5.4%
138	Pneumonia, Lipid	5.4%
139	Pharyngeal Diseases	5.2%
140	Hemoptysis	5.2%
141	Pertussis	5.2%
142	Respiratory Hypersensitivity	5.1%
143	Angioedema	4.9%
144	Serum Sickness	4.9%
145	Transfusion Reaction	4.8%
146	Hypotensive Transfusion Reaction	4.8%
147	Bronchiolitis Obliterans	4.8%
148	Nasopharyngitis	4.8%
149	Ear Neoplasms	4.8%
150	Anti-Glomerular Basement Membrane Disease	4.7%
151	Asbestosis	4.7%
152	Berylliosis	4.7%
153	Silicosis	4.7%
154	Tonsillitis	4.7%
155	Cystic Fibrosis	4.7%
156	Blastomycosis	4.6%
157	Airway Obstruction	4.6%
158	Choking	4.6%
159	Epiglottitis	4.6%
160	Chronic Obstructive Airway Disease	4.6%
161	Mediastinitis	4.6%
162	Middle Lobe Syndrome	4.6%
163	Acute Lung Injury	4.6%
164	Transfusion-Related Acute Lung Injury	4.5%
165	Granulomatosis with polyangiitis	4.4%
166	Pharyngeal Neoplasms	4.2%
167	Sick Building Syndrome	4.1%
168	Multiple Chemical Sensitivity	4.1%
169	Aphonia	4.1%
170	Retropharyngeal Abscess	4.1%
171	Dysphonia	4.1%
172	Vasculitis, Leukocytoclastic, Cutaneous	4.1%
173	Glomerulonephritis, Membranoproliferative	4%
174	Mediastinal Cyst	3.9%
175	Pericardial Cyst	3.9%
176	Persistent Fetal Circulation Syndrome	3.9%
177	Thymic Cyst	3.9%
178	Histiocytosis, Langerhans-Cell	3.8%
179	Mediastinal Emphysema	3.8%
180	Pulmonary Aspergillosis	3.8%
181	Bronchopulmonary Aspergillosis	3.8%
182	Hypoventilation	3.8%
183	Acidosis, Respiratory	3.8%
184	Alkalosis, Respiratory	3.8%
185	Sarcoidosis, Pulmonary	3.8%
186	Sleep Apnea Syndromes	3.8%
187	Pulmonary Infarction	3.8%
188	Mastocytosis	3.5%
189	Drug Eruptions	3.5%
190	Dermatitis, Allergic Contact	3.5%
191	Otosclerosis	3.3%
192	Tympanosclerosis	3.3%
193	Labyrinthitis	3.3%
194	Dyspnea, Paroxysmal	3.3%
195	Respiratory Paralysis	3.3%
196	Pulmonary Emphysema	3.2%
197	Thrombocytopenic purpura	3.1%
198	Antiphospholipid Syndrome	3%
199	Nasopharyngeal Neoplasms	3%
200	Autoimmune Lymphoproliferative Syndrome	2.9%
201	Angioedemas, Hereditary	2.9%
202	Bronchomalacia	2.9%
203	Tracheomalacia	2.9%
204	Tympanic Membrane Perforation	2.8%
205	Peritonsillar Abscess	2.8%
206	Otomycosis	2.8%
207	Congenital Microtia	2.8%
208	Deglutition Disorders	2.8%
209	Bronchopulmonary Dysplasia	2.7%
210	Sleep Apnea, Obstructive	2.7%
211	Sleep Apnea, Central	2.7%
212	Autoimmune thrombocytopenia	2.7%
213	Immune thrombocytopenic purpura	2.7%
214	Lupus Erythematosus, Systemic	2.5%
215	Lymphoproliferative Disorders	2.5%
216	Overlap syndrome	2.5%
217	Addison Disease	2.5%
218	Paraproteinemias	2.5%
219	Pemphigus	2.5%
220	Autoimmune thyroiditis	2.5%
221	Primary Adrenal Insufficiency	2.5%
222	Lymphopenia	2.5%
223	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.5%
224	Autoimmune hepatitis	2.5%
225	Hypopharyngeal Neoplasms	2.4%
226	Hypopharyngeal Cancer	2.4%
227	Rhinitis, Allergic, Perennial	2.4%
228	Mastocytosis, Systemic	2.4%
229	Hereditary Angioedema Type III	2.4%
230	Hereditary Angioedema Types I and II	2.4%
231	Dysacusis	2.4%
232	Invasive Pulmonary Aspergillosis	2.3%
233	Hypergammaglobulinemia	2.1%
234	Latent Autoimmune Diabetes in Adults	2.1%
235	Agammaglobulinemia	2.1%
236	Dermatitis Herpetiformis	2.1%
237	HIV Infections	2.1%
238	Acute Generalized Exanthematous Pustulosis	2.1%
239	Herpes Zoster Oticus	2.1%
240	Primary amyloidosis	2%
241	Monoclonal Gammopathy of Undetermined Significance	2%
242	Cochlear Diseases	2%
243	Otitis Externa	2%
244	Otitis Media	2%
245	Vestibular Diseases	2%
246	Endolymphatic Hydrops	2%
247	Rheumatoid Arthritis	1.9%
248	Juvenile arthritis	1.9%
249	Graves Disease	1.9%
250	Erythema Nodosum	1.8%
251	Eosinophilic Granuloma	1.8%
252	Dermatitis, Photoallergic	1.8%
253	Nasopharyngeal carcinoma	1.8%
254	Acoustic Neuroma	1.7%
255	Vestibulocochlear Nerve Diseases	1.7%
256	Multiple Myeloma	1.6%
257	Lemierre Syndrome	1.6%
258	Tonsillar Neoplasms	1.6%
259	Kernicterus	1.5%
260	Toxic Epidermal Necrolysis	1.5%
261	Stevens-Johnson Syndrome	1.5%
262	Hyperacusis	1.4%
263	Tinnitus	1.4%
264	Phonophobia	1.4%
265	Hearing Loss	1.4%
266	Plasmacytoma	1.4%
267	Tumor Lysis Syndrome	1.4%
268	Ataxia Telangiectasia	1.4%
269	HTLV-I Infections	1.4%
270	Job Syndrome	1.4%
271	Hydrops Fetalis	1.3%
272	Meniere Disease	1.3%
273	Otitis Media with Effusion	1.3%
274	Lymphoma	1.2%
275	Myasthenia Gravis	1.2%
276	Uveomeningoencephalitic Syndrome	1.2%
277	Chronic granulomatous disease	1.2%
278	Heavy Chain Disease	1.2%
279	HIV Seropositivity	1.2%
280	Sezary Syndrome	1.1%
281	Vestibular Neuronitis	1.1%
282	Stiff-Person Syndrome	1%
283	Polyradiculoneuropathy	1%
284	Polyradiculoneuritis	1%
285	Acquired Immunodeficiency Syndrome	1%
286	AIDS related complex	1%
287	Infectious Mononucleosis	1%
288	Cryoglobulinemia	1%
289	Felty Syndrome	1%
290	POEMS Syndrome	1%
291	Lupus Nephritis	1%
292	Myasthenia Gravis, Autoimmune, Experimental	1%
293	Schnitzler Syndrome	1%
294	Vertigo	0.9%
295	Mastoiditis	0.9%
296	Petrositis	0.9%
297	AIDS-Related Opportunistic Infections	0.9%
298	Deafness	0.9%
299	Hearing Loss, Sudden	0.9%
300	Hearing Loss, Bilateral	0.9%
301	Hearing Loss, High-Frequency	0.9%
302	Hearing Loss, Mixed Conductive-Sensorineural	0.9%
303	Hearing Loss, Unilateral	0.9%
304	Complete Hearing Loss	0.9%
305	Deaf Mutism	0.9%
306	Vasculitis, Central Nervous System	0.9%
307	HIV Wasting Syndrome	0.9%
308	Rheumatoid Vasculitis	0.9%
309	AIDS Dementia Complex	0.9%
310	AIDS-Associated Nephropathy	0.9%
311	Lupus Vasculitis, Central Nervous System	0.9%
312	Lambert-Eaton Myasthenic Syndrome	0.8%
313	Waldenstrom Macroglobulinemia	0.8%
314	Wiskott-Aldrich Syndrome	0.8%
315	Sicca Syndrome	0.8%
316	Sjogren's Syndrome	0.8%
317	HIV-Associated Lipodystrophy Syndrome	0.8%
318	Multiple Sclerosis	0.7%
319	Hodgkin Disease	0.7%
320	Leukemia, Plasma Cell	0.7%
321	Lymphoma, Non-Hodgkin	0.7%
322	Leukemia, T-Cell	0.7%
323	Leukemia, B-Cell	0.7%
324	Neuromyelitis Optica	0.7%
325	Leukoencephalitis, Acute Hemorrhagic	0.7%
326	Auditory Perceptual Disorders	0.6%
327	Composite Lymphoma	0.6%
328	Encephalomyelitis, Acute Disseminated	0.6%
329	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.6%
330	Neuritis, Autoimmune, Experimental	0.6%
331	Lymphangioleiomyomatosis	0.6%
332	Guillain-Barre Syndrome	0.5%
333	Multiple Sclerosis, Chronic Progressive	0.5%
334	Multiple Sclerosis, Relapsing-Remitting	0.5%
335	Lymphoma, Follicular	0.5%
336	T-Cell Lymphoma	0.5%
337	Mantle cell lymphoma	0.5%
338	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
339	Leukemia, Large Granular Lymphocytic	0.5%
340	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
341	Giant Cell Arteritis	0.4%
342	Temporal Arteritis	0.4%
343	Myelitis, Transverse	0.4%
344	Lymphoma, T-Cell, Cutaneous	0.3%
345	Lymphoma, AIDS-Related	0.3%
346	Enteropathy-Associated T-Cell Lymphoma	0.3%
347	Primary Effusion Lymphoma	0.3%
348	Lymphomatoid Granulomatosis	0.3%
349	Mycosis Fungoides	0.3%
350	Lymphomatoid Papulosis	0.3%
351	Plasmablastic lymphoma	0.3%
352	Miller Fisher Syndrome	0.3%
353	Burkitt Lymphoma	0.3%

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