MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hidradenitis Suppurativa

(UMLS:C0162836)

Definition:: A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.
UMLS ID:: C0162836
MeSH ID:: D017497

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.825.420|C01.539.800.720.420|C01.539.830.499

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.838.765.420|C17.800.946.315.320

Synonym(s)

Hidradenitis Suppurativa

Acne inversa

Apocrine acne

HIDRADENITIS SUPPURATIVA

Hidradenitis axillaris

Hidradenitis suppurativa

Pyoderma fistulans significa

Smoker's boils

Suppurative hidradenitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Minocycline		12522319	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Mycetoma	49.3%
2	Ecthyma	47.4%
3	Erysipelas	46%
4	Staphylococcal Skin Infections	46%
5	Erythrasma	45%
6	Erythema Chronicum Migrans	44.8%
7	Erythema Induratum	37.2%
8	Impetigo	35.9%
9	Dermatomycoses	34.9%
10	Staphylococcal Scalded Skin Syndrome	34.8%
11	Rhinoscleroma	34.5%
12	Cellulitis	32.4%
13	Furunculosis	31.6%
14	furuncle	31.6%
15	carbuncle	29.3%
16	Candidiasis, Chronic Mucocutaneous	24.7%
17	Cutaneous Candidiasis	24.7%
18	Chromoblastomycosis	23.3%
19	Dermatophytosis	23.3%
20	Sporotrichosis	23.3%
21	Tinea	23.3%
22	Tinea Versicolor	23.3%
23	Trichophytosis	23.3%
24	Hyalohyphomycosis	23.3%
25	Bacteremia	22.3%
26	Pyoderma Gangrenosum	22.2%
27	Tinea Capitis	22.2%
28	Onychomycosis	22.2%
29	Pelvic Infection	21.5%
30	Wound Infection	21.5%
31	Soft Tissue Infection	21.5%
32	Community-Acquired Infections	21.5%
33	Ulcerative stomatitis	20.7%
34	Blastomycosis	20.3%
35	Bacterial Endocarditis	20.1%
36	Central Nervous System Bacterial Infections	19.2%
37	Syphilis	19.2%
38	Abscess	19.2%
39	Empyema	19.2%
40	Lupus Erythematosus, Cutaneous	19.1%
41	Panniculitis	19.1%
42	Systemic Scleroderma	19.1%
43	Morphea	19.1%
44	Eye Infection	19%
45	Respiratory Tract Infections	19%
46	Bone Diseases, Infectious	18.7%
47	Pregnancy Complications, Infectious	18.7%
48	Skin Diseases, Infectious	18.7%
49	Arthritis, Infectious	18.5%
50	Xeroderma Pigmentosum	18.4%
51	Cross Infection	18.4%
52	Septicemia	18.4%
53	Sepsis	18.4%
54	Tinea Pedis	18%
55	Borrelia Infections	17.8%
56	Leptospirosis	17.8%
57	Dermatitis, Atopic	17.8%
58	Epidermolysis Bullosa	17.8%
59	Fusariosis	17.6%
60	Endotoxemia	17.5%
61	Lyme Neuroborreliosis	17.3%
62	Brain Abscess	17.3%
63	Lyme Disease	17.1%
64	Relapsing Fever	17.1%
65	Opportunistic Infections	17%
66	Acne Vulgaris	16.9%
67	Contact Dermatitis	16.9%
68	Eczema	16.9%
69	Erythema Multiforme	16.9%
70	Intertrigo	16.9%
71	Neurodermatitis	16.9%
72	Rhinophyma	16.9%
73	Perioral Dermatitis	16.9%
74	Acne	16.9%
75	Pyomyositis	16.8%
76	Subacute Bacterial Endocarditis	16.7%
77	Piedra	16.6%
78	Chlamydia Infections	16.6%
79	Gonorrhea	16.6%
80	Breast Diseases	16.6%
81	Dermatitis	16.6%
82	Exanthema	16.6%
83	Facial Dermatoses	16.6%
84	Hair Diseases	16.6%
85	Hand Dermatoses	16.6%
86	keratoacanthoma	16.6%
87	Keratosis	16.6%
88	Nail Diseases	16.6%
89	Photosensitivity Disorders	16.6%
90	Prurigo	16.6%
91	Pyoderma	16.6%
92	Rosacea	16.6%
93	Sebaceous Gland Diseases	16.6%
94	Skin Diseases, Vesiculobullous	16.6%
95	Skin Ulcer	16.6%
96	Skin Diseases, Papulosquamous	16.6%
97	Skin Diseases, Vascular	16.6%
98	Acneiform Eruptions	16.6%
99	Ocular Rosacea	16.6%
100	Subcorneal pustular dermatosis	16.6%
101	Erythematotelangiectatic Rosacea	16.6%
102	Papulopustular Rosacea	16.6%
103	Chronic Actinic Dermatitis	16.6%
104	Anhidrosis	16.4%
105	Hypohidrosis	16.4%
106	Miliaria	16.4%
107	Miliaria Rubra	16.4%
108	Mycoses	16.4%
109	Urinary tract infection	16.3%
110	Psoas Abscess	16.3%
111	Abdominal Abscess	16.3%
112	Pertussis	16.1%
113	Gram-Negative Bacterial Infections	16%
114	Gram-Positive Bacterial Infections	16%
115	Neurosyphilis	15.2%
116	Dermatitis Herpetiformis	14.9%
117	Skin Diseases, Bacterial	14.9%
118	Sexually Transmitted Diseases	14.8%
119	Acrodermatitis	14.8%
120	Sebaceous Gland Neoplasms	14.8%
121	Porokeratosis	14.8%
122	Gianotti-Crosti Syndrome	14.8%
123	Keratoderma, Palmoplantar	14.8%
124	Dermatomyositis	14.7%
125	Fungemia	14.7%
126	Foot Diseases	14.6%
127	Dermatitis, Phototoxic	14.6%
128	Pityriasis Lichenoides et Varioliformis Acuta	14.6%
129	Pityriasis Lichenoides	14.6%
130	Phototoxicity	14.6%
131	Necrobiosis Lipoidica Diabeticorum	14.6%
132	Panniculitis, Lupus Erythematosus	14.5%
133	Joint Tuberculosis	14.4%
134	Tuberculosis, Osteoarticular	14.4%
135	Bone Tuberculosis	14.4%
136	Hidradenitis Suppurativa	14.4%
137	Skin Abnormalities	14.4%
138	Skin Neoplasms	14.4%
139	Pigmentation Disorders	14.4%
140	Lipomatosis	14.2%
141	Pruritus	14.2%
142	Erythema	14.2%
143	Necrolytic Migratory Erythema	14.2%
144	Cutaneous Fistula	14.2%
145	Nephrogenic Fibrosing Dermopathy	14.2%
146	Nephrogenic Systemic Fibrosis	14.2%
147	Central Nervous System Infection	14.1%
148	Foot Ulcer	14%
149	Erythema Infectiosum	14%
150	Exanthema Subitum	13.9%
151	Panophthalmitis	13.7%
152	Bacterial Vaginosis	13.6%
153	Candidemia	13.6%
154	Hordeolum	13.6%
155	Bacterial conjunctivitis	13.5%
156	Xeroderma	13.3%
157	Human Ehrlichiosis	13%
158	Dermatitis, Photoallergic	13%
159	Lymphogranuloma Venereum	12.9%
160	Pseudoxanthoma Elasticum	12.7%
161	Lung Abscess	12.5%
162	Mastocytosis	12.4%
163	Urticaria Pigmentosa	12.2%
164	Pneumonia, Bacterial	12%
165	Ectodermal Dysplasia	11.9%
166	Aplasia Cutis Congenita	11.9%
167	Ophthalmia Neonatorum	11.9%
168	Trachoma	11.9%
169	Endophthalmitis	11.8%
170	Peritonitis	11.8%
171	Japanese Spotted Fever	11.8%
172	Osteomyelitis	11.7%
173	Periostitis	11.7%
174	Surgical Wound Infection	11.7%
175	Human anaplasmosis	11.7%
176	Adnexitis	11.7%
177	Pelvic Inflammatory Disease	11.7%
178	Cutis Laxa	11.6%
179	Liver Abscess	11.5%
180	Lupus Erythematosus, Discoid	11.3%
181	Scleroderma, Limited	11.3%
182	Dermatitis, Irritant	11.2%
183	Acne Conglobata	11.2%
184	Retropharyngeal Abscess	10.9%
185	Epidural Abscess	10.9%
186	Erythema Nodosum	10.9%
187	Peritonsillar Abscess	10.8%
188	Bacterial Infections	10.7%
189	Toxic Epidermal Necrolysis	10.7%
190	Stevens-Johnson Syndrome	10.7%
191	Superinfection	10.5%
192	Actinomycetales Infections	10.4%
193	Bordetella Infections	10.4%
194	Brucellosis	10.4%
195	Campylobacter infection	10.4%
196	Clostridium Infections	10.4%
197	Enterobacteriaceae Infections	10.4%
198	Listeriosis	10.4%
199	Pseudomonas Infections	10.4%
200	Q Fever	10.4%
201	Staphylococcal Infections	10.4%
202	Streptococcal Infections	10.4%
203	Vibrio Infections	10.4%
204	Helicobacter Infections	10.4%
205	Bacillaceae Infections	10.4%
206	Neisseriaceae Infections	10.4%
207	Burkholderia Infections	10.4%
208	Clostridium difficile infection	10.4%
209	Flavobacteriaceae Infections	10.4%
210	Moraxellaceae Infections	10.4%
211	Burkholderia cepacia Infection	10.4%
212	Corneal Ulcer	10.4%
213	Puerperal Infection	10.3%
214	Spondylitis	10.3%
215	Appendicitis	10.2%
216	Bacteriuria	10.2%
217	Pyuria	10.2%
218	Endotoxic shock	10.2%
219	Septic Shock	10.2%
220	Toxic Shock Syndrome	10.2%
221	Connective Tissue Diseases	10.2%
222	Meningitis, Listeria	10.1%
223	Rocky Mountain Spotted Fever	10.1%
224	Dermatitis, Occupational	10%
225	Suppuration	10%
226	Tuberculosis, Spinal	9.9%
227	Cholesteatoma	9.8%
228	Pressure Ulcer	9.8%
229	Folliculitis	9.8%
230	Foot Dermatoses	9.8%
231	Gynecomastia	9.8%
232	Hypertrichosis	9.8%
233	Hypotrichosis	9.8%
234	Leg Ulcer	9.8%
235	Parakeratosis	9.8%
236	Parapsoriasis	9.8%
237	Pityriasis	9.8%
238	Psoriasis	9.8%
239	Sweet Syndrome	9.8%
240	Onycholysis	9.8%
241	Hyperpigmentation	9.8%
242	Lichenoid Eruptions	9.8%
243	Chloracne	9.8%
244	Ichthyosis, X-Linked	9.8%
245	Dermatitis, Allergic Contact	9.8%
246	Sjogren-Larsson Syndrome	9.8%
247	Papillon-Lefevre Disease	9.8%
248	Toxoplasmosis, Cerebral	9.6%
249	Sweating, Gustatory	9.4%
250	Auriculotemporal Syndrome	9.4%
251	Syphilis, Congenital	9.4%
252	Aspergillosis	9.4%
253	Candidiasis	9.4%
254	Coccidioidomycosis	9.4%
255	Histoplasmosis	9.4%
256	Paracoccidioidomycosis	9.4%
257	Zygomycosis	9.4%
258	Phaeohyphomycosis	9.4%
259	Pneumocystis Infections	9.4%
260	Lice Infestations	9.3%
261	Erysipelothrix infection	9.2%
262	Meningitis, Haemophilus	9.2%
263	Meningitis, Pneumococcal	9.2%
264	Arthritis, Reactive	9%
265	Granuloma Annulare	9%
266	Neuroaspergillosis	9%
267	Behcet Syndrome	9%
268	Hyperkeratosis, Epidermolytic	8.8%
269	Acantholysis	8.5%
270	Breast Cyst	8.5%
271	Actinic keratosis	8.5%
272	Pemphigoid, Benign Mucous Membrane	8.5%
273	Pemphigus	8.5%
274	Sunburn	8.5%
275	Argyria	8.5%
276	Hirsutism	8.5%
277	Lactation Disorder	8.5%
278	Mastitis	8.5%
279	Urticaria	8.5%
280	Adiposis Dolorosa	8.4%
281	Pruritus Vulvae	8.4%
282	Mastocytoma	8.4%
283	Pruritus Ani	8.4%
284	Diverticulitis	8.4%
285	Diaper Rash	8.3%
286	AIDS-Related Opportunistic Infections	8.3%
287	Sweat Gland Diseases	8.3%
288	Larva Migrans	8.3%
289	Leishmaniasis	8.3%
290	Molluscum Contagiosum	8.3%
291	Albinism	8.2%
292	Onchocerciasis	8.2%
293	Otomycosis	8.1%
294	Central Nervous System Fungal Infections	8.1%
295	Meningitis, Bacterial	7.8%
296	Invasive Pulmonary Aspergillosis	7.8%
297	Tuberculosis, Meningeal	7.6%
298	Acinetobacter Infections	7.6%
299	Actinomycosis	7.6%
300	Bacteroides Infections	7.6%
301	Cholera	7.6%
302	Corynebacterium Infections	7.6%
303	Escherichia coli Infections	7.6%
304	Gas Gangrene	7.6%
305	Haemophilus Infections	7.6%
306	Klebsiella Infections	7.6%
307	Meningococcal Infections	7.6%
308	Mycobacterium Infections	7.6%
309	Mycoplasma Infections	7.6%
310	Nocardia Infections	7.6%
311	Pasteurella Infections	7.6%
312	Pneumococcal Infections	7.6%
313	Proteus Infections	7.6%
314	Rickettsia Infections	7.6%
315	Salmonella infections	7.6%
316	Scarlet Fever	7.6%
317	Scrub Typhus	7.6%
318	Tetanus	7.6%
319	Serratia Infections	7.6%
320	Ureaplasma Infections	7.6%
321	Pulmonary Nocardiosis	7.6%
322	Mucocutaneous Lymph Node Syndrome	7.5%
323	Drug Eruptions	7.4%
324	Diverticulum	7.4%
325	Lipodystrophy	7.4%
326	Livedo Reticularis	7.4%
327	Malignant Atrophic Papulosis	7.4%
328	Diverticulosis	7.4%
329	Warts	7.4%
330	Polyarteritis Nodosa	7.3%
331	Takayasu Arteritis	7.3%
332	Discitis	7.3%
333	Mastoiditis	7.3%
334	Petrositis	7.3%
335	Liver Abscess, Amebic	7.2%
336	Lung Diseases, Fungal	7.2%
337	Meningitis, Cryptococcal	6.9%
338	Nail-Patella Syndrome	6.7%
339	Porphyrias, Hepatic	6.6%
340	Lichen Planus	6.5%
341	Melanosis	6.5%
342	Chloasma	6.5%
343	Pityriasis Rosea	6.5%
344	Pityriasis Rubra Pilaris	6.5%
345	Vitiligo	6.5%
346	Lichen Nitidus	6.5%
347	Diphtheria	6.2%
348	Leprosy	6.2%
349	Mycobacterium Infections, Nontuberculous	6.2%
350	Psittacosis	6.2%
351	Paratyphoid Fever	6.2%
352	Plague	6.2%
353	Tuberculosis	6.2%
354	Typhoid Fever	6.2%
355	TYPHUS	6.2%
356	Yersinia pseudotuberculosis Infections	6.2%
357	Bubonic Plague	6.2%
358	Mycobacterium abscessus Infection	6.2%
359	Leishmaniasis, Cutaneous	6.1%
360	Eczema Herpeticum	6.1%
361	Mucormycosis	6%
362	Rheumatic Fever	5.8%
363	Enterocolitis, Pseudomembranous	5.7%
364	pseudomembranous colitis	5.7%
365	Dysentery, Bacillary	5.7%
366	Alopecia	5.7%
367	Androgenetic Alopecia	5.7%
368	Infection	5.6%
369	Varicose Ulcer	5.6%
370	Breast Neoplasms, Male	5.6%
371	Triple Negative Breast Neoplasms	5.6%
372	Galactorrhea	5.6%
373	Mycobacterium avium-intracellulare Infection	5.5%
374	Lymph Node Tuberculosis	5.5%
375	Tuberculosis, Miliary	5.5%
376	Tuberculosis, Multidrug-Resistant	5.5%
377	Leprosy, Multibacillary	5.5%
378	Latent Tuberculosis	5.5%
379	Collagen Diseases	5.5%
380	Mixed Connective Tissue Disease	5.5%
381	Mucinoses	5.5%
382	Salmonella Infections, Animal	5.5%
383	Epidermodysplasia Verruciformis	5.4%
384	Herpes Labialis	5.4%
385	Rheumatic Heart Disease	5.4%
386	Salmonella food poisoning	5.4%
387	Oral candidiasis	5.2%
388	Borderline leprosy	5.2%
389	Leprosy, Lepromatous	5.2%
390	Tuberculoid leprosy	5.2%
391	Extensively Drug-Resistant Tuberculosis	5.2%
392	Pulmonary Aspergillosis	5.2%
393	Bronchopulmonary Aspergillosis	5.2%
394	Botulism	5.1%
395	Waterhouse-Friderichsen Syndrome	5%
396	Angioedema	4.9%
397	Hidradenitis	4.9%
398	Condylomata Acuminata	4.9%
399	Giant Cell Arteritis	4.9%
400	Temporal Arteritis	4.9%
401	Acanthosis Nigricans	4.9%
402	Alopecia Areata	4.9%
403	Cartilage Diseases	4.9%
404	Lentigo	4.9%
405	Rheumatism	4.9%
406	Chondromalacia	4.9%
407	Acute Generalized Exanthematous Pustulosis	4.9%
408	Tuberculosis, Gastrointestinal	4.8%
409	Lupus Erythematosus, Systemic	4.8%
410	Overlap syndrome	4.8%
411	Tuberculosis, Central Nervous System	4.8%
412	CREST Syndrome	4.7%
413	Meningitis, Fungal	4.5%
414	Candidiasis, Vulvovaginal	4.5%
415	Serum Sickness	4.3%
416	Variegate Porphyria	4.3%
417	Acute intermittent porphyria	4.3%
418	Porphyria Cutanea Tarda	4.3%
419	Carcinoma, Lobular	4.3%
420	Arthritis, Psoriatic	4.3%
421	Tuberculosis, Pulmonary	4.3%
422	Lichen Planus, Oral	4.2%
423	Dupuytren Contracture	4.1%
424	Menkes Kinky Hair Syndrome	3.9%
425	HIV-Associated Lipodystrophy Syndrome	3.5%
426	Lemierre Syndrome	3.4%
427	Angioedemas, Hereditary	3.3%
428	Scleromyxedema	3.3%
429	Diabetic Foot	3.3%
430	Tuberculosis, Renal	3.2%
431	Hereditary Angioedema Type III	3%
432	Hereditary Angioedema Types I and II	3%
433	Noonan Syndrome	3%
434	Mesenteric Panniculitis	2.8%
435	Panniculitis, Peritoneal	2.8%
436	Tietze's Syndrome	2.8%
437	Orbital Cellulitis	2.8%
438	Myxoid cyst	2.8%
439	Myxedema	2.8%
440	Marfan Syndrome	2.8%
441	Peutz-Jeghers Syndrome	2.7%
442	Homocystinuria	2.7%
443	Aspergillosis, Allergic Bronchopulmonary	2.6%
444	Osteochondritis	2.5%
445	Polymyalgia Rheumatica	2.5%
446	Osteogenesis Imperfecta	2.5%
447	Keloid	2.4%
448	Rheumatoid Arthritis	2.2%
449	Juvenile arthritis	2.2%
450	Lupus Nephritis	2.2%
451	Laryngomalacia	2%
452	Pectus carinatum	2%
453	Rheumatoid Nodule	1.6%
454	Felty Syndrome	1.5%
455	Bronchomalacia	1.5%
456	Tracheomalacia	1.5%
457	Rheumatoid Vasculitis	1.3%
458	Mucopolysaccharidosis III	1.3%
459	Lupus Vasculitis, Central Nervous System	1.2%
460	Sicca Syndrome	1.2%
461	Sjogren's Syndrome	1.2%
462	Mucopolysaccharidosis II	1%

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