MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Angiodysplasia

(UMLS:C0085411)

Definition:: Acquired degenerative dilation or expansion (ectasia) of normal BLOOD VESSELS, often associated with aging. They are isolated, tortuous, thin-walled vessels and sources of bleeding. They occur most often in mucosal capillaries of the GASTROINTESTINAL TRACT leading to GASTROINTESTINAL HEMORRHAGE and ANEMIA.
UMLS ID:: C0085411
MeSH ID:: D016888

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.075

Synonym(s)

Angiodysplasia

ANGIODYSPLASIA

angiodysplasia

angiodysplasias

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Dabigatran	FAERS: 7	US FAERS
2	Rivaroxaban	FAERS: 4	US FAERS
3	Warfarin	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
4	apixaban	FAERS: 4	US FAERS
5	Warfarin	FAERS: 3	US FAERS
6	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 2	US FAERS
7	Amiodarone	FAERS: 2	US FAERS
8	Lenalidomide	FAERS: 2	US FAERS
9	Octreotide	FAERS: 2	US FAERS
10	Alendronate	FAERS: 1	US FAERS
11	Aleve PM	FAERS: 1	US FAERS
12	Amiodarone	FAERS: 1	US FAERS
13	Azacitidine	FAERS: 1	US FAERS
14	Bosentan	FAERS: 1	OFFSIDES US FAERS
15	Celecoxib	FAERS: 1	OFFSIDES US FAERS
16	Daunorubicin	FAERS: 1	US FAERS
17	Everolimus	FAERS: 1	US FAERS
18	Galantamine	FAERS: 1	US FAERS
19	Imatinib Mesylate	FAERS: 1	US FAERS
20	Sumatriptan	FAERS: 1	US FAERS
21	Sunitinib	FAERS: 1	US FAERS
22	ambrisentan	FAERS: 1	US FAERS
23	carbidopa, levodopa drug combination	FAERS: 1	US FAERS
24	zolmitriptan	FAERS: 1	US FAERS
25	5-O-[1-[3,3-Diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydron;chloride		OFFSIDES
26	Acenocoumarol		OFFSIDES
27	Chlorpropamide		OFFSIDES
28	Ciprofloxacin		OFFSIDES
29	Digoxin		OFFSIDES
30	Dipyridamole		OFFSIDES
31	Eplerenone		OFFSIDES
32	Erythromycin		OFFSIDES
33	Glipizide		OFFSIDES
34	Lactulose		OFFSIDES
35	Mannitol		OFFSIDES
36	Nateglinide		OFFSIDES
37	Octreotide	Canada Vigilance: 1	Canada Vigilance
38	Ofloxacin		OFFSIDES
39	Olanzapine		OFFSIDES
40	Pentaerythritol Tetranitrate		OFFSIDES
41	Phenprocoumon		OFFSIDES
42	Piperacillin		OFFSIDES
43	Propranolol		OFFSIDES
44	Sevelamer		OFFSIDES
45	Sevelamer		OFFSIDES
46	Sodium ferric gluconate complex		OFFSIDES
47	Sunitinib		OFFSIDES
48	Tazobactam		OFFSIDES
49	Triamterene		OFFSIDES
50	Vitamin D		OFFSIDES
51	chlorhexidine gluconate		OFFSIDES
52	glimepiride		OFFSIDES
53	methenolone acetate		OFFSIDES
54	pirbuterol		OFFSIDES
55	polystyrene sulfonic acid		OFFSIDES
56	rofecoxib		OFFSIDES
57	trandolapril		OFFSIDES
58	voglibose		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Aneurysm	42.9%
2	Angiomatosis	42.9%
3	Aortic Diseases	42.9%
4	Arterial Occlusive Diseases	42.9%
5	Hyperemia	42.9%
6	Hypotension	42.9%
7	Superior Vena Cava Syndrome	42.9%
8	Telangiectasis	42.9%
9	Vasculitis	42.9%
10	Venous Insufficiency	42.9%
11	Peripheral Vascular Diseases	42.9%
12	Embolism and Thrombosis	42.9%
13	Capillary Leak Syndrome	42.9%
14	Prehypertension	42.9%
15	Aortic Aneurysm	40.9%
16	Aortitis	40.9%
17	Leriche Syndrome	40.9%
18	Periphlebitis	40.9%
19	Phlebitis	40.9%
20	Thromboangiitis Obliterans	40.9%
21	Myocardial Ischemia	38.1%
22	Postphlebitic Syndrome	37.1%
23	Thrombophlebitis	35.8%
24	Blue Toe Syndrome	34.3%
25	Aortic Aneurysm, Abdominal	33.3%
26	Aortic Aneurysm, Thoracic	33.3%
27	Retinal Vein Occlusion	32.5%
28	Coronary Aneurysm	31.7%
29	Aneurysm, Dissecting	31%
30	Arteriosclerosis	31%
31	Arteritis	31%
32	Embolism	31%
33	Erythromelalgia	31%
34	Fibromuscular Dysplasia	31%
35	Malignant Hypertension	31%
36	Raynaud Disease	31%
37	Thromboembolism	31%
38	Thrombosis	31%
39	Essential Hypertension	31%
40	Aneurysm, Ruptured	31%
41	Iliac Aneurysm	31%
42	Pulmonary artery stenosis	31%
43	White Coat Hypertension	31%
44	Systemic Vasculitis	31%
45	Embolus	31%
46	Malignant Atrophic Papulosis	30.5%
47	Shwartzman Phenomenon	30.3%
48	Aortic Rupture	30.2%
49	Vascular System Injuries	30%
50	Coronary Thrombosis	28.9%
51	Coronary Artery Disease	28.9%
52	Compartment syndromes	28.6%
53	Hepatic Veno-Occlusive Disease	28.6%
54	Peliosis Hepatis	28.6%
55	Varicocele	28.6%
56	Carotid Artery Thrombosis	28.4%
57	Cerebrovascular Disorders	27.9%
58	Diabetic Angiopathies	27.9%
59	Reperfusion Injury	27.9%
60	Splenic Infarction	27.9%
61	Cerebrovascular Insufficiency	27.9%
62	Vascular Neoplasms	27.9%
63	Spinal Cord Vascular Diseases	27.9%
64	Vasoplegia	27.9%
65	Hemorrhoids	27.6%
66	Thoracic Outlet Syndrome	27.6%
67	Intracranial Embolism and Thrombosis	27.5%
68	Carotid Stenosis	27.4%
69	Intracranial Aneurysm	27.4%
70	Coronary heart disease	27.3%
71	Myocardial Infarction	27.3%
72	Acute Coronary Syndrome	27.3%
73	Myocardial Reperfusion Injury	26.8%
74	Arteriosclerosis Obliterans	25.4%
75	Atherosclerosis	25.4%
76	Air Embolism	25.4%
77	Endarteritis	25.4%
78	Venous Thrombosis	25.4%
79	Deep Vein Thrombosis	25.4%
80	Venous Thromboembolism	25.4%
81	Moyamoya Disease	25.3%
82	Polyarteritis Nodosa	25%
83	Takayasu Arteritis	25%
84	Intracranial Arteriosclerosis	24.7%
85	Cerebral Atherosclerosis	24.7%
86	Cerebral Arteriosclerosis	24.7%
87	Cerebral Thrombosis	23.4%
88	Intracranial Embolism	23.4%
89	Intracranial Thrombosis	23.4%
90	Heart Diseases	23.1%
91	Coronary Occlusion	22.2%
92	Microvascular Angina	22.2%
93	Coronary Stenosis	22.2%
94	ST segment elevation myocardial infarction	22.2%
95	Hand-Arm Vibration Syndrome	21.8%
96	Arteriovenous fistula	21.6%
97	Sinus Thrombosis, Intracranial	21.3%
98	Optic Neuropathy, Ischemic	21.1%
99	Anterior Ischemic Optic Neuropathy	21.1%
100	Mesenteric vascular insufficiency	21.1%
101	Retinal Artery Occlusion	20.9%
102	Retinal Vasculitis	20.9%
103	Hypertensive Retinopathy	20.9%
104	Kounis Syndrome	20.7%
105	Anterior Compartment Syndrome	20.5%
106	Vasculitis, Leukocytoclastic, Cutaneous	20.5%
107	Abdominal Compartment Syndrome	20.5%
108	Cavernous Sinus Thrombosis	20.3%
109	Sagittal Sinus Thrombosis	20.3%
110	Angioedema	20.3%
111	Vasculitis, Central Nervous System	20.3%
112	Colitis, Ischemic	20.3%
113	Carotid Artery Diseases	20.2%
114	Brain Ischemia	20.2%
115	Hypotension, Orthostatic	20.2%
116	Cerebrovascular accident	20.2%
117	Varicose Ulcer	20.2%
118	Vasospasm, Intracranial	20.2%
119	Spinal Cord Ischemia	20.2%
120	Intracranial Arterial Diseases	20.2%
121	Primary Graft Dysfunction	20.2%
122	Post-Exercise Hypotension	20.2%
123	May-Thurner Syndrome	20.2%
124	Angina Pectoris	20.1%
125	Coronary Restenosis	19.8%
126	Embolism, Amniotic Fluid	19.7%
127	Brain Infarction	19.6%
128	Lemierre Syndrome	18.9%
129	Giant Cell Arteritis	18.5%
130	Temporal Arteritis	18.5%
131	Infarction, Middle Cerebral Artery	17.8%
132	Infarction, Anterior Cerebral Artery	17.8%
133	Infarction, Posterior Cerebral Artery	17.8%
134	Cerebral Infarction	17.5%
135	Brain Stem Infarctions	17.5%
136	Intermittent Claudication	17.2%
137	Pulmonary Embolism	17.2%
138	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	17.2%
139	Subarachnoid Hemorrhage, Traumatic	17%
140	Carotid Artery, Internal, Dissection	17%
141	No-Reflow Phenomenon	16.9%
142	Shock, Cardiogenic	16.7%
143	Cerebral Arterial Diseases	16.6%
144	Vertebrobasilar Insufficiency	16.6%
145	Anterior Spinal Artery Syndrome	16.6%
146	Basilar Artery Stenosis	16.6%
147	Vertebral Artery Stenosis	16.6%
148	Intracranial Hemorrhage, Hypertensive	16.6%
149	Transient Cerebral Ischemia	16.6%
150	Vertebral Artery Dissection	16.5%
151	Angina, Unstable	16.4%
152	Lateral Medullary Syndrome	16.4%
153	Mesenteric Vascular Occlusion	15.5%
154	Mucocutaneous Lymph Node Syndrome	15.5%
155	CREST Syndrome	15.5%
156	Hepatic Vein Thrombosis	15.4%
157	Budd-Chiari Syndrome	15.4%
158	Diabetic Retinopathy	15.4%
159	Sturge-Weber Syndrome	15.4%
160	Livedo Reticularis	15.3%
161	Renal hypertension	15.1%
162	Renal Artery Obstruction	15.1%
163	Renal Artery Stenosis	15.1%
164	Pulmonary Infarction	15.1%
165	Hemangioma, Cavernous	15%
166	Pregnancy Complications, Cardiovascular	15%
167	Cardiovascular Abnormalities	15%
168	Basal Ganglia Cerebrovascular Disease	15%
169	Vascular Headaches	14.9%
170	Scurvy	14.9%
171	Subclavian Steal Syndrome	14.8%
172	Scimitar Syndrome	14.8%
173	Angina Pectoris, Variant	14.6%
174	Cardiac Tamponade	14.3%
175	Endocarditis	14.3%
176	Cardiac Arrest	14.3%
177	Heart failure	14.3%
178	Pericardial effusion	14.3%
179	Pericarditis	14.3%
180	Pneumopericardium	14.3%
181	Cor pulmonale	14.3%
182	Ventricular Outflow Obstruction	14.3%
183	Ventricular Dysfunction	14.3%
184	Cardiomyopathies	14.3%
185	Pleuropericarditis	14.3%
186	Carotid Artery Injuries	14.1%
187	Aortic Valve Stenosis	13.6%
188	Cardiomyopathy, Dilated	13.6%
189	Pulmonary Valve Stenosis	13.6%
190	Basal Ganglia Hemorrhage	13.1%
191	Hypertension, Renovascular	12.3%
192	Subarachnoid Hemorrhage	12.3%
193	Hypoxia-Ischemia, Brain	12.3%
194	Cerebral Hemorrhage	12.3%
195	Hereditary Angioedema Type III	12.2%
196	Hereditary Angioedema Types I and II	12.2%
197	Ischemic contracture	12.2%
198	Angioedemas, Hereditary	12.1%
199	Tricuspid Atresia	12.1%
200	Arrhythmogenic Right Ventricular Dysplasia	12.1%
201	Putaminal Hemorrhage	12%
202	Cryoglobulinemia	12%
203	Leukomalacia, Periventricular	12%
204	Diabetic Foot	11.9%
205	Hypertrophic Cardiomyopathy	11.7%
206	Hypertrophic obstructive cardiomyopathy	11.7%
207	Granulomatosis with polyangiitis	11.3%
208	Supravalvular aortic stenosis	11.1%
209	Lown-Ganong-Levine Syndrome	11.1%
210	Cerebral Amyloid Angiopathy	11%
211	Dementia, Vascular	11%
212	Aortic Valve Insufficiency	10.3%
213	Restrictive cardiomyopathy	10.3%
214	Endocardial Fibroelastosis	10.3%
215	Heart Rupture, Post-Infarction	10.3%
216	Mitral Valve Insufficiency	10.3%
217	Mitral Valve Stenosis	10.3%
218	Myocarditis	10.3%
219	Pericarditis, Constrictive	10.3%
220	Pulmonary Valve Insufficiency	10.3%
221	Tricuspid Valve Insufficiency	10.3%
222	Tricuspid Valve Stenosis	10.3%
223	Ventricular Dysfunction, Left	10.3%
224	Right Ventricular Dysfunction	10.3%
225	Endomyocardial Fibrosis	10.3%
226	Carditis	10.3%
227	Heart Failure, Systolic	10.3%
228	Heart Failure, Diastolic	10.3%
229	Heart Block	10.2%
230	Tachycardia	10.2%
231	Tachyarrhythmia	10.2%
232	Aortic coarctation	10.1%
233	Cor Triatriatum	10.1%
234	Coronary Vessel Anomalies	10.1%
235	Patent ductus arteriosus	10.1%
236	Ebstein Anomaly	10.1%
237	Heart Septal Defects	10.1%
238	Tetralogy of Fallot	10.1%
239	Transposition of Great Vessels	10.1%
240	Hypoplastic Left Heart Syndrome	10.1%
241	Pituitary Apoplexy	10%
242	Shy-Drager Syndrome	9.9%
243	Purpura, Hyperglobulinemic	9.9%
244	Bacterial Endocarditis	9.7%
245	Cardiac Output, High	9.5%
246	Myocardial Stunning	9.5%
247	Low Cardiac Output Syndrome	9.5%
248	Cardiomegaly	9.3%
249	Postpericardiotomy Syndrome	9.3%
250	Cardiac Hypertrophy	9.3%
251	Rheumatic Heart Disease	9.1%
252	Behcet Syndrome	8.6%
253	Waldenstrom Macroglobulinemia	8.6%
254	Multiple Myeloma	8.6%
255	Aortic Valve Prolapse	8.5%
256	Tricuspid Valve Prolapse	8.5%
257	Takotsubo Cardiomyopathy	8.5%
258	Rheumatoid Vasculitis	8.3%
259	Adams-Stokes Syndrome	8.3%
260	Atrioventricular Block	8.3%
261	Bundle-Branch Block	8.3%
262	Atrial Premature Complexes	8.3%
263	Sinoatrial Block	8.3%
264	Tachycardia, Paroxysmal	8.3%
265	Supraventricular tachycardia	8.3%
266	Tachycardia, Ventricular	8.3%
267	Wolff-Parkinson-White Syndrome	8.3%
268	Tachycardia, Reciprocating	8.3%
269	Aortopulmonary Septal Defect	8.2%
270	Double Outlet Right Ventricle	8.2%
271	Endocardial Cushion Defects	8.2%
272	Myocardial bridging	8.2%
273	Aorticopulmonary Septal Defect	8.2%
274	Sick Sinus Syndrome	8.2%
275	Lupus Vasculitis, Central Nervous System	8.2%
276	Dextrocardia	8.1%
277	Long QT Syndrome	8.1%
278	Ataxia Telangiectasia	7.6%
279	Pseudoxanthoma Elasticum	7.6%
280	Tachycardia, Atrioventricular Nodal Reentry	7.3%
281	Tachycardia, Ectopic Atrial	7.3%
282	Tachycardia, Ectopic Junctional	7.3%
283	Sinus Tachycardia	7.3%
284	Torsades de Pointes	7.3%
285	Accelerated Idioventricular Rhythm	7.3%
286	Truncus Arteriosus, Persistent	7.3%
287	Sinus Arrhythmia	6.8%
288	Atrial Fibrillation	6.8%
289	Atrial Flutter	6.8%
290	Edema, Cardiac	6.8%
291	Ventricular Fibrillation	6.8%
292	Ventricular Flutter	6.8%
293	Parasystole	6.8%
294	Paroxysmal atrial fibrillation	6.8%
295	Bradycardia	6.8%
296	Diabetic Cardiomyopathies	6.8%
297	Cardiomyopathy, Alcoholic	6.7%
298	Ectopia Cordis	6.7%
299	Sudden Cardiac Death	6.7%
300	Left Ventricular Hypertrophy	6.7%
301	Right Ventricular Hypertrophy	6.7%
302	Single umbilical artery	6.7%
303	Chagas Cardiomyopathy	6.7%
304	Romano-Ward Syndrome	6.6%
305	Hematoma, Subdural	6.3%
306	Hematoma, Epidural, Cranial	6.3%
307	Subacute Bacterial Endocarditis	6.1%
308	Hematoma, Subdural, Intracranial	5.9%
309	Hematoma, Subdural, Chronic	5.9%
310	Hematoma, Subdural, Acute	5.9%
311	Noonan Syndrome	5.8%
312	Sinus Arrest, Cardiac	5.6%
313	Brain Hemorrhage, Traumatic	5.5%
314	Carcinoid Heart Disease	5.3%
315	Marfan Syndrome	5.1%
316	Dyspnea, Paroxysmal	5%
317	MELAS Syndrome	4.9%
318	Dural Arteriovenous Fistula	4.1%
319	Fabry Disease	3.7%
320	Williams Syndrome	3%
321	Turner Syndrome	2.8%
322	Kartagener Syndrome	2.6%
323	Kearns-Sayre syndrome	1.8%

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