MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

(UMLS:C1961099)

Definition:: A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
UMLS ID:: C1961099
MeSH ID:: D054218

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.337.428.600.620

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.515.560.600.620

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.683.515.528.600.620

Synonym(s)

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Acute T Cell Leukemia

Acute T Cell Lymphoblastic Leukemia

Acute T-Cell Leukemia

Acute T-Cell Lymphoblastic Leukemia

Acute T-cell lymphoblastic leukemia

Cortical T ALL

Pre T-ALL

Pre-T ALL

10.

Precursor T-Lymphoblastic Leukemia

11.

Precursor T-cell lymphoblastic leukemia

12.

Precursor T-lymphoblastic leukemia (T-cell ALL)

13.

Pro-T ALL

14.

T Acute Lymphoblastic Leukemia

15.

T-ALL

16.

T-Cell Acute Lymphoblastic Leukemia

17.

T-Cell Type Acute Leukemia

18.

T-cell ALL

19.

T-cell acute lymphoblastic leukaemia

20.

T-cell acute lymphoblastic leukemia

21.

T-cell acute lymphoblastic leukemias

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3,3'-diindolylmethane	22514694	CTD
2	Arsenicals	27313752	CTD
3	BMS-906024	27148573	CTD
4	CHOP protocol	7511314	CTD
5	Cyclophosphamide	20167372 20463610	CTD
6	Cyclosporine	3865016	CTD
7	Cytarabine	12426685 16831976 20167372	CTD
8	Daunorubicin	12426685 20167372	CTD
9	Dexamethasone	12426685 20167372	CTD
10	Doxorubicin	20167372	CTD
11	Etoposide	3865016	CTD
12	Hydrocortisone	8711459 20463610	CTD
13	MRK 003	19246562	CTD
14	Mercaptopurine	20167372	CTD
15	Methotrexate	View details 8711459 16831976 20167372 20463610	CTD
16	Prednisolone	20463610	CTD
17	Prednisone	20167372	CTD
18	Resveratrol	19063842	CTD
19	Sirolimus	19246562	CTD
20	Thioguanine	17015055 20167372	CTD
21	Thiotepa	8711459	CTD
22	Vincristine	12426685 20167372 20463610	CTD
23	dibenzo(a,l)pyrene	21863085	CTD
24	nelarabine	16831976 20658590	CTD
25	pirarubicin	20463610	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	49.2%
2	Leukemia, T-Cell	36%
3	Leukemia, B-Cell	36%
4	Lymphoma	26.6%
5	Leukemia, Large Granular Lymphocytic	23.8%
6	Tumor Lysis Syndrome	22.7%
7	Autoimmune Lymphoproliferative Syndrome	18.8%
8	Sezary Syndrome	18.4%
9	Leukemia, Plasma Cell	17.4%
10	Infectious Mononucleosis	17.4%
11	Composite Lymphoma	16.6%
12	Plasmacytoma	16.2%
13	Hodgkin Disease	15.3%
14	Lymphoma, Non-Hodgkin	15.3%
15	Primary amyloidosis	15.1%
16	Heavy Chain Disease	14.3%
17	Sarcoidosis	14.1%
18	Histiocytic Disorders, Malignant	13.8%
19	Lymphangioleiomyomatosis	13.7%
20	Agammaglobulinemia	13.4%
21	Waldenstrom Macroglobulinemia	12.8%
22	Multiple Myeloma	12.8%
23	Leukemia, Experimental	12%
24	Lymphocele	12%
25	Granuloma	11.5%
26	Adenitis	11%
27	Histiocytosis	11%
28	Lymphadenitis	11%
29	Lymphangitis	11%
30	Lymphedema	11%
31	Neoplasms, Germ Cell and Embryonal	11%
32	Neoplasms, Glandular and Epithelial	11%
33	Splenic Diseases	11%
34	Thymus Hyperplasia	11%
35	Pseudolymphoma	11%
36	Lymphadenopathy	11%
37	Germ Cell Cancer	11%
38	Paraproteinemias	10.5%
39	Thymus Neoplasms	10.5%
40	Leukemia, Radiation-Induced	10.4%
41	Lymphoma, Follicular	9.8%
42	T-Cell Lymphoma	9.8%
43	Mantle cell lymphoma	9.8%
44	Neuroectodermal Tumors	9.7%
45	Sarcoma, Myeloid	9.6%
46	Lymphatic Abnormalities	9%
47	Thymoma	8.9%
48	Transfusion Reaction	8.9%
49	Hypotensive Transfusion Reaction	8.9%
50	Hypergammaglobulinemia	8.9%
51	Neoplasms, Neuroepithelial	8.8%
52	Gliomatosis cerebri	8.8%
53	Leukemia L1210	8.4%
54	Leukemia P388	8.4%
55	Monoclonal Gammopathy of Undetermined Significance	8.3%
56	Lymphomatoid Granulomatosis	8.3%
57	Lymphangiectasis, Intestinal	8.1%
58	Splenic Neoplasms	7.9%
59	Carcinosarcoma	7.7%
60	Hemangiosarcoma	7.7%
61	Malignant histiocytosis	7.7%
62	lymphangiosarcoma	7.7%
63	Histiocytic sarcoma	7.7%
64	Leukemia, Myelomonocytic, Chronic	7.7%
65	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.7%
66	Mucocutaneous Lymph Node Syndrome	7.4%
67	Meningioma	7.4%
68	melanoma	7.2%
69	Autoimmune Diseases	7.2%
70	Hamartoma	7.2%
71	Hypersensitivity	7.2%
72	Immunologic Deficiency Syndromes	7.2%
73	Neoplasms, Hormone-Dependent	7.2%
74	Neoplasms, Multiple Primary	7.2%
75	Paraneoplastic Syndromes	7.2%
76	Precancerous Conditions	7.2%
77	Neoplasms, Second Primary	7.2%
78	Immune reconstitution syndrome	7.2%
79	Immune Reconstitution Inflammatory Syndrome	7.2%
80	Lymphoma, T-Cell, Cutaneous	7.1%
81	Lymphoma, AIDS-Related	7.1%
82	Enteropathy-Associated T-Cell Lymphoma	7.1%
83	Primary Effusion Lymphoma	7.1%
84	Sarcoidosis, Pulmonary	6.8%
85	Trophoblastic Neoplasms	6.6%
86	Carcinoma 256, Walker	6.5%
87	Adenoma	6%
88	Ameloblastoma	6%
89	Angiokeratoma	6%
90	Carcinoma	6%
91	Chordoma	6%
92	Elephantiasis	6%
93	Hemangioma	6%
94	hemangiopericytoma	6%
95	Hypersplenism	6%
96	Lymphangioma	6%
97	Mesenchymoma	6%
98	Nevus	6%
99	Teratoma	6%
100	Hepatoblastoma	6%
101	Mixed Tumor, Mullerian	6%
102	Germinoma	6%
103	Teratocarcinoma	6%
104	Angiofibroma	6%
105	Elephantiasis Nostras Verrucosa	6%
106	Sarcoma	6%
107	Epithelioma	6%
108	Hematologic Neoplasms	6%
109	Carcinoma, Ehrlich Tumor	5.9%
110	Dermoid Cyst	5.9%
111	Carcinoma, Lewis Lung	5.9%
112	Cyst	5.8%
113	Neoplastic Processes	5.8%
114	Neoplastic Syndromes, Hereditary	5.8%
115	Pregnancy Complications, Neoplastic	5.8%
116	Mycosis Fungoides	5.8%
117	Lymphomatoid Papulosis	5.8%
118	Plasmablastic lymphoma	5.8%
119	Basal cell carcinoma	5.8%
120	Carcinoma, Papillary	5.8%
121	Squamous cell carcinoma	5.8%
122	Chondrosarcoma	5.8%
123	Craniopharyngioma	5.8%
124	Cystadenoma	5.8%
125	leiomyosarcoma	5.8%
126	liposarcoma	5.8%
127	Mesothelioma	5.8%
128	synovial sarcoma	5.8%
129	Neuroectodermal Tumor, Melanotic	5.8%
130	Angiomyolipoma	5.8%
131	Clear Cell Sarcoma of Soft Tissue	5.8%
132	Alveolar Soft Part Sarcoma	5.8%
133	Neuroendocrine Tumors	5.8%
134	Carcinoma, Basal Cell	5.8%
135	Neoplasms, Experimental	5.7%
136	Adenoma, Acidophil	5.6%
137	Ganglioneuroma	5.6%
138	Glioma	5.6%
139	Malignant Glioma	5.6%
140	Melanoma, Experimental	5.4%
141	Burkitt Lymphoma	5.4%
142	Medulloblastoma	5.3%
143	Leukemia, Myeloid, Chronic-Phase	5.1%
144	Splenic Infarction	4.9%
145	Sarcoma, Experimental	4.9%
146	Histiocytosis, Langerhans-Cell	4.9%
147	Cryoglobulinemia	4.8%
148	Multiple Endocrine Neoplasia	4.8%
149	Neoplasms, Radiation-Induced	4.8%
150	Endometrial Stromal Sarcoma	4.8%
151	Cystadenocarcinoma	4.8%
152	Fibrosarcoma	4.8%
153	Osteosarcoma	4.8%
154	Mucoepidermoid Carcinoma	4.8%
155	Carcinoid Tumor	4.8%
156	Neurilemmoma	4.8%
157	Hutchinson's Melanotic Freckle	4.8%
158	Melanoma, Amelanotic	4.8%
159	Glomerulonephritis, Membranoproliferative	4.7%
160	Choriocarcinoma	4.6%
161	Carcinoma, Lobular	4.6%
162	Thrombocytopenic purpura	4.5%
163	Acanthoma	4.5%
164	Autoimmune thrombocytopenia	4.3%
165	Immune thrombocytopenic purpura	4.3%
166	Adenofibroma	4.3%
167	Fibroadenoma	4.3%
168	Malignant Fibrous Histiocytoma	4.3%
169	POEMS Syndrome	4.2%
170	Splenic Rupture	4.2%
171	Disseminated Intravascular Coagulation	4.1%
172	Protein S Deficiency	4.1%
173	Bone Marrow Neoplasms	4.1%
174	Astrocytoma	4%
175	Ependymoma	4%
176	oligodendroglioma	4%
177	Ganglioglioma	4%
178	gliosarcoma	4%
179	Anaplastic astrocytoma	4%
180	Anaplastic Oligodendroglioma	4%
181	Lymphopenia	3.9%
182	Retinoblastoma	3.9%
183	Paraneoplastic Encephalomyelitis	3.9%
184	Nephroblastoma	3.8%
185	Mammary Neoplasms, Experimental	3.8%
186	Mastocytosis	3.8%
187	Transfusion-Related Acute Lung Injury	3.8%
188	Bowen's Disease	3.8%
189	Paraganglioma	3.8%
190	Rhabdomyosarcoma	3.8%
191	Giant Cell Tumor of Bone	3.8%
192	Tuberous Sclerosis	3.8%
193	Abdominal Neoplasms	3.7%
194	Anemia	3.7%
195	Blood Coagulation Disorders	3.7%
196	Blood Platelet Disorders	3.7%
197	Bone Marrow Diseases	3.7%
198	Erythroplasia	3.7%
199	Follicular cyst	3.7%
200	Head and Neck Neoplasms	3.7%
201	Hemorrhagic Disorders	3.7%
202	Immune Complex Diseases	3.7%
203	Leukocyte Disorders	3.7%
204	Methemoglobinemia	3.7%
205	Mucocele	3.7%
206	Pancytopenia	3.7%
207	Pilonidal Cyst	3.7%
208	Polycythemia	3.7%
209	Soft Tissue Neoplasms	3.7%
210	Sulfhemoglobinemia	3.7%
211	Thoracic Neoplasms	3.7%
212	Thyroglossal Cyst	3.7%
213	Antiphospholipid Syndrome	3.7%
214	Synovial Cyst	3.7%
215	Thrombophilia	3.7%
216	Latex allergy	3.7%
217	Erythrocytosis	3.7%
218	Aberrant Crypt Foci	3.7%
219	Adenocarcinoma	3.6%
220	Carcinoma in Situ	3.6%
221	Carcinoma, Transitional Cell	3.6%
222	Phyllodes Tumor	3.6%
223	Dysgerminoma	3.6%
224	Hemangioendothelioma	3.6%
225	Lipoma	3.6%
226	Lymphohistiocytosis, Hemophagocytic	3.6%
227	Myoma	3.6%
228	Myxoma	3.6%
229	Neuroma	3.6%
230	Papilloma	3.6%
231	Pseudomyxoma Peritonei	3.6%
232	Seminoma	3.6%
233	Papillomatosis	3.6%
234	Angiolipoma	3.6%
235	Myelolipoma	3.6%
236	Neoplasms, Bone Tissue	3.6%
237	Neoplasms, Fibrous Tissue	3.6%
238	Smooth Muscle Tumor	3.6%
239	Adenomatosis, Pulmonary	3.6%
240	Adenomatous Polyps	3.6%
241	Carcinoma, Large Cell	3.6%
242	Carcinoma, Small Cell	3.6%
243	Desmoplastic Small Round Cell Tumor	3.6%
244	Schnitzler Syndrome	3.6%
245	Erdheim-Chester Disease	3.6%
246	Chondroma	3.6%
247	Enchondroma	3.6%
248	Malignant Carcinoid Syndrome	3.6%
249	Sarcoma 180	3.5%
250	Thrombocythemia, Essential	3.5%
251	Dermatofibrosarcoma	3.3%
252	Dermatofibrosarcoma Protuberans	3.3%
253	Neurofibrosarcoma	3.3%
254	Hemangioma, Cavernous	3.2%
255	Glioblastoma	3.2%
256	Neuroblastoma	3.2%
257	Glioblastoma Multiforme	3.2%
258	Basal Cell Nevus Syndrome	3.1%
259	Digestive System Neoplasms	3.1%
260	Endocrine Gland Neoplasms	3.1%
261	Eye Neoplasms	3.1%
262	Nervous System Neoplasms	3.1%
263	Environmental Illness	3.1%
264	Mesoblastic Nephroma	3%
265	Thrombasthenia	3%
266	Antithrombin III Deficiency	3%
267	Protein C Deficiency	3%
268	Bone neoplasms	3%
269	Leukoplakia	3%
270	Lupus Erythematosus, Systemic	3%
271	Pancreatic Cyst	3%
272	Pregnancy Complications, Hematologic	3%
273	Skin Neoplasms	3%
274	Overlap syndrome	3%
275	Addison Disease	3%
276	Barrett Esophagus	3%
277	Breast Cyst	3%
278	Actinic keratosis	3%
279	Mediastinal Cyst	3%
280	Neoplasm Invasiveness	3%
281	Neoplasm Metastasis	3%
282	Neoplasm Recurrence, Local	3%
283	Parovarian Cyst	3%
284	Pemphigus	3%
285	Pericardial Cyst	3%
286	Thymic Cyst	3%
287	Carcinogenesis	3%
288	Autoimmune thyroiditis	3%
289	Myxoid cyst	3%
290	Primary Adrenal Insufficiency	3%
291	Metastasis	3%
292	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.9%
293	Autoimmune hepatitis	2.9%
294	Mastocytosis, Systemic	2.9%
295	Pheochromocytoma	2.8%
296	Alveolar rhabdomyosarcoma	2.8%
297	Hepatocellular Adenoma	2.8%
298	Ganglioneuroblastoma	2.8%
299	Polycythemia Vera	2.7%
300	Wiskott-Aldrich Syndrome	2.7%
301	Vitamin K Deficiency	2.7%
302	Carcinoma, Pancreatic Ductal	2.7%
303	Multiple Endocrine Neoplasia Type 1	2.6%
304	Hydrops Fetalis	2.6%
305	Carcinoid Heart Disease	2.6%
306	Thrombocytosis	2.6%
307	Job Syndrome	2.6%
308	Kernicterus	2.6%
309	Afibrinogenemia	2.5%
310	Factor VII Deficiency	2.5%
311	Factor X Deficiency	2.5%
312	Factor XII Deficiency	2.5%
313	Hemophilia A	2.5%
314	Activated Protein C Resistance	2.5%
315	Factor II deficiency	2.5%
316	Factor VIII Deficiency	2.5%
317	Factor V deficiency	2.5%
318	Factor XI Deficiency	2.5%
319	Hypoprothrombinemias	2.5%
320	Acoustic Neuroma	2.5%
321	Latent Autoimmune Diabetes in Adults	2.5%
322	Dermatitis Herpetiformis	2.5%
323	Kounis Syndrome	2.5%
324	Liver Neoplasms, Experimental	2.5%
325	HIV Infections	2.5%
326	Sturge-Weber Syndrome	2.5%
327	Corpus Luteum Cyst	2.4%
328	Ovarian Cysts	2.4%
329	Eosinophilic Granuloma	2.4%
330	Splenosis	2.4%
331	Gastrointestinal Stromal Tumors	2.4%
332	Prolactinoma	2.4%
333	Growth Hormone-Secreting Pituitary Adenoma	2.4%
334	neurofibroma	2.4%
335	Hydatidiform Mole	2.4%
336	Adenoid Cystic Carcinoma	2.4%
337	fibroma	2.4%
338	Fibromatosis	2.4%
339	Osteoblastoma	2.4%
340	Osteoma	2.4%
341	Rhabdomyoma	2.4%
342	Chondromatosis	2.4%
343	Adenocarcinoma, Clear Cell	2.4%
344	Cholangiocarcinoma	2.4%
345	Cervical Intraepithelial Neoplasia	2.4%
346	Hemangioblastoma	2.4%
347	Lymphoma, Extranodal NK-T-Cell	2.4%
348	Lambert-Eaton Myasthenic Syndrome	2.4%
349	Parathyroid Neoplasms	2.4%
350	Peritoneal Neoplasms	2.4%
351	Thyroid Neoplasm	2.4%
352	Thyroid carcinoma	2.4%
353	Optic Nerve Glioma	2.3%
354	Adenomatous Polyposis Coli	2.2%
355	Chronic granulomatous disease	2.2%
356	Rheumatoid Arthritis	2.1%
357	Choledochal Cyst	2.1%
358	Juvenile arthritis	2.1%
359	granulosa cell tumor	2.1%
360	Carcinoma, Ovarian Epithelial	2.1%
361	Graves Disease	2.1%
362	Pancreatic Neoplasm	2.1%
363	Peutz-Jeghers Syndrome	2.1%
364	Anti-Glomerular Basement Membrane Disease	2.1%
365	Vipoma	2.1%
366	Asthma, Aspirin-Induced	2%
367	anaphylaxis	2%
368	Anemia, Hemolytic	2%
369	Anemia, Macrocytic	2%
370	Eosinophilia	2%
371	Food Allergy	2%
372	Hypoproteinemia	2%
373	Leukopenia	2%
374	Retroperitoneal Neoplasms	2%
375	Thrombocytopenia	2%
376	Leukostasis	2%
377	MYELODYSPLASTIC SYNDROME	2%
378	Anaphylactic shock	2%
379	Mastocytoma	1.9%
380	Hemoglobinuria, Paroxysmal	1.9%
381	Leukemoid Reaction	1.9%
382	Tracheal Neoplasms	1.9%
383	Leukoplakia, Oral	1.9%
384	Paraneoplastic Cerebellar Degeneration	1.8%
385	Serum Sickness	1.8%
386	Fibromatosis, Aggressive	1.8%
387	Fibromatosis, Abdominal	1.8%
388	Klatskin Tumor	1.8%
389	insulinoma	1.8%
390	Purpura, Thrombotic Thrombocytopenic	1.7%
391	Respiratory Hypersensitivity	1.7%
392	Nasopharyngeal carcinoma	1.7%
393	Denys-Drash Syndrome	1.6%
394	Anemia, Neonatal	1.6%
395	Leukocytosis	1.6%
396	Mouth Neoplasms	1.6%
397	Pelger-Huet Anomaly	1.6%
398	Sick Building Syndrome	1.6%
399	Central Nervous System Neoplasms	1.6%
400	Pleocytosis	1.6%
401	Multiple Chemical Sensitivity	1.6%
402	Vascular Neoplasms	1.6%
403	Esophageal Neoplasms	1.6%
404	Myelitis, Transverse	1.6%
405	Anemia, Sickle Cell	1.6%
406	Thalassemia	1.6%
407	Genital Neoplasms, Female	1.6%
408	Pancreatic Pseudocyst	1.6%
409	Urticaria	1.6%
410	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
411	Limbic Encephalitis	1.6%
412	HTLV-I Infections	1.6%
413	Lymphatic Metastasis	1.6%
414	Neoplasms, Unknown Primary	1.6%
415	Leukemic Infiltration	1.6%
416	Breast Neoplasms, Male	1.6%
417	Neoplasm Micrometastasis	1.6%
418	Triple Negative Breast Neoplasms	1.6%
419	Anemia, Diamond-Blackfan	1.6%
420	Adrenocortical carcinoma	1.6%
421	Leydig Cell Tumor	1.5%
422	Gastrinoma	1.5%
423	Glucagonoma	1.5%
424	Ataxia Telangiectasia	1.5%
425	Testicular Neoplasms	1.5%
426	Renal Cell Carcinoma	1.4%
427	Papillary Renal Cell Carcinoma	1.4%
428	Thyroid Nodule	1.4%
429	Adrenal Gland Neoplasms	1.4%
430	Gastrointestinal Neoplasms	1.4%
431	Genital Neoplasms, Male	1.4%
432	Liver neoplasms	1.4%
433	Uveal Neoplasms	1.4%
434	Myasthenia Gravis	1.4%
435	Urologic Neoplasms	1.4%
436	Uveomeningoencephalitic Syndrome	1.4%
437	Drug Eruptions	1.4%
438	Ecchymosis	1.4%
439	Petechiae	1.4%
440	Purpura	1.4%
441	Sebaceous Gland Neoplasms	1.4%
442	Spinal Neoplasms	1.4%
443	Xeroderma Pigmentosum	1.4%
444	Granulomatosis with polyangiitis	1.3%
445	Dermatitis, Allergic Contact	1.3%
446	HIV Seropositivity	1.3%
447	Polycystic Ovary Syndrome	1.3%
448	Carcinoma, Endometrioid	1.3%
449	Opsoclonus-Myoclonus Syndrome	1.3%
450	Dupuytren Contracture	1.2%
451	Purpura, Hyperglobulinemic	1.2%
452	Urticaria Pigmentosa	1.2%
453	Primary Myelofibrosis	1.2%
454	Agranulocytosis	1.2%
455	Anemia, Megaloblastic	1.2%
456	Lymphocytosis	1.2%
457	Myelofibrosis	1.2%
458	Myeloid Metaplasia	1.2%
459	Milk Allergy	1.2%
460	Hypoalbuminemia	1.2%
461	Wheat Hypersensitivity	1.2%
462	Hypereosinophilic syndrome	1.2%
463	bone marrow fibrosis	1.2%
464	Thrombotic Microangiopathies	1.2%
465	Stiff-Person Syndrome	1.2%
466	Polyradiculoneuropathy	1.2%
467	Polyradiculoneuritis	1.2%
468	Acquired Immunodeficiency Syndrome	1.2%
469	AIDS related complex	1.2%
470	Felty Syndrome	1.2%
471	Lupus Nephritis	1.1%
472	Hemolytic-Uremic Syndrome	1.1%
473	Myasthenia Gravis, Autoimmune, Experimental	1.1%
474	Waterhouse-Friderichsen Syndrome	1.1%
475	AIDS-Related Opportunistic Infections	1%
476	Vasculitis, Central Nervous System	1%
477	Sickle Cell Trait	1%
478	Dermatitis, Atopic	1%
479	ovarian neoplasm	1%
480	HIV Wasting Syndrome	1%
481	Rheumatoid Vasculitis	1%
482	AIDS Dementia Complex	1%
483	AIDS-Associated Nephropathy	1%
484	Nose Neoplasms	1%
485	Meningeal Neoplasms	1%
486	Pituitary Adenoma	0.9%
487	Pituitary Neoplasms	0.9%
488	Lupus Vasculitis, Central Nervous System	0.9%
489	Fanconi Anemia	0.9%
490	Sicca Syndrome	0.9%
491	Sjogren's Syndrome	0.9%
492	Palatal Neoplasms	0.9%
493	HIV-Associated Lipodystrophy Syndrome	0.9%
494	Ear Neoplasms	0.8%
495	Eyelid Neoplasms	0.8%
496	Lung Neoplasms	0.8%
497	Pleural Neoplasms	0.8%
498	Eosinophilia-Myalgia Syndrome	0.8%
499	Acute Chest Syndrome	0.8%
500	Zollinger-Ellison syndrome	0.8%
501	Angioedema	0.8%
502	Cell Transformation, Viral	0.8%
503	Brain Neoplasms	0.8%
504	Multiple Sclerosis	0.8%
505	Salivary Gland Neoplasms	0.8%
506	Shwartzman Phenomenon	0.8%
507	Spinal Cord Neoplasms	0.8%
508	Tongue Neoplasms	0.8%
509	Scurvy	0.8%
510	Uterine Neoplasms	0.8%
511	Vaginal Neoplasms	0.8%
512	Vulvar Neoplasms	0.8%
513	Purpura Fulminans	0.8%
514	Uterine Cancer	0.8%
515	Acute Generalized Exanthematous Pustulosis	0.8%
516	Fallopian Tube Neoplasms	0.8%
517	Neutropenia	0.8%
518	Atypical Hemolytic Uremic Syndrome	0.8%
519	Neuromyelitis Optica	0.7%
520	Leukoencephalitis, Acute Hemorrhagic	0.7%
521	Niemann-Pick Disease, Type C	0.7%
522	Pharyngeal Neoplasms	0.7%
523	Asthma	0.7%
524	Central Nervous System Cysts	0.7%
525	Bile Duct Neoplasms	0.7%
526	gallbladder neoplasm	0.7%
527	Intestinal Neoplasms	0.7%
528	Penile Neoplasms	0.7%
529	Prostatic Neoplasms	0.7%
530	Stomach Neoplasms	0.7%
531	Encephalomyelitis, Acute Disseminated	0.7%
532	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.7%
533	Erythema Nodosum	0.7%
534	Neuritis, Autoimmune, Experimental	0.7%
535	Dermatitis, Photoallergic	0.7%
536	Pulmonary Eosinophilia	0.6%
537	Eosinophilic Pneumonia	0.6%
538	Meningeal Carcinomatosis	0.6%
539	Anemia, Pernicious	0.6%
540	Laryngeal neoplasm	0.6%
541	Aspergillosis, Allergic Bronchopulmonary	0.6%
542	Guillain-Barre Syndrome	0.6%
543	Bladder Neoplasm	0.6%
544	Kidney Neoplasm	0.6%
545	Ureteral Neoplasms	0.6%
546	Urethral Neoplasms	0.6%
547	Febrile Neutropenia	0.6%
548	Bronchial Neoplasms	0.5%
549	Asthma, Exercise-Induced	0.5%
550	Status Asthmaticus	0.5%
551	Multiple Pulmonary Nodules	0.5%
552	Toxic Epidermal Necrolysis	0.5%
553	Stevens-Johnson Syndrome	0.5%
554	Supratentorial Neoplasms	0.5%
555	Multiple Sclerosis, Chronic Progressive	0.5%
556	Multiple Sclerosis, Relapsing-Remitting	0.5%
557	Endometrial Neoplasms	0.5%
558	Pseudoxanthoma Elasticum	0.5%
559	Giant Cell Arteritis	0.5%
560	Temporal Arteritis	0.5%
561	Asthma, Occupational	0.5%
562	Farmer's Lung	0.5%
563	Angioedemas, Hereditary	0.5%
564	Hypopharyngeal Neoplasms	0.5%
565	Pleural Effusion, Malignant	0.5%
566	Hypopharyngeal Cancer	0.5%
567	Hay fever	0.5%
568	Rhinitis, Allergic, Perennial	0.5%
569	Parotid Neoplasms	0.5%
570	Prostatic Neoplasms, Castration-Resistant	0.5%
571	Nelson Syndrome	0.5%
572	Cecal Neoplasms	0.4%
573	Duodenal Neoplasms	0.4%
574	Hereditary Angioedema Type III	0.4%
575	Hereditary Angioedema Types I and II	0.4%
576	Brain Stem Neoplasms	0.4%
577	Nasopharyngeal Neoplasms	0.4%
578	Colorectal Neoplasms	0.4%
579	Tonsillar Neoplasms	0.3%
580	Cerebellar Neoplasms	0.3%
581	Choroid Plexus Papilloma	0.3%
582	Paranasal Sinus Neoplasms	0.3%
583	Radicular Cyst	0.3%
584	Appendiceal Neoplasms	0.3%
585	Colonic Neoplasms	0.3%
586	Rectal Neoplasms	0.3%
587	Miller Fisher Syndrome	0.3%
588	Maxillary Sinus Neoplasms	0.2%
589	Anus Neoplasms	0.2%
590	Sigmoid Neoplasms	0.2%

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