MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Intracranial Arteriosclerosis

(UMLS:C0007771)

Definition:: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.
UMLS ID:: C0007771
MeSH ID:: D002537

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.510.800

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.137.126.372|C14.907.253.560.350

Synonym(s)

Intracranial Arteriosclerosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cholesterol		30672636	CTD
2	alpha-Linolenic Acid		30672636	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Moyamoya Disease	46.2%
2	Intracranial Aneurysm	45.7%
3	Cerebral Arterial Diseases	42.9%
4	Carotid Stenosis	34.9%
5	Intracranial Embolism and Thrombosis	34.8%
6	Carotid Artery Diseases	34%
7	Brain Ischemia	34%
8	Cerebrovascular accident	34%
9	Vasospasm, Intracranial	34%
10	Basal Ganglia Cerebrovascular Disease	34%
11	Infarction, Middle Cerebral Artery	33.1%
12	Infarction, Anterior Cerebral Artery	33.1%
13	Infarction, Posterior Cerebral Artery	33.1%
14	Brain Infarction	32%
15	Vascular Headaches	32%
16	Leriche Syndrome	31.3%
17	Thromboangiitis Obliterans	31.3%
18	Vasculitis, Central Nervous System	30.9%
19	Carotid Artery Thrombosis	29.3%
20	Leukomalacia, Periventricular	29.2%
21	Arteriosclerosis Obliterans	28.9%
22	Atherosclerosis	28.9%
23	Coronary Artery Disease	27.9%
24	Cerebral Amyloid Angiopathy	26.8%
25	Myocardial Ischemia	26.8%
26	Malignant Atrophic Papulosis	26.2%
27	Carotid Artery Injuries	26%
28	Spinal Cord Vascular Diseases	24.8%
29	Aneurysm	24.7%
30	Angiomatosis	24.7%
31	Aortic Diseases	24.7%
32	Hyperemia	24.7%
33	Hypotension	24.7%
34	Superior Vena Cava Syndrome	24.7%
35	Telangiectasis	24.7%
36	Vasculitis	24.7%
37	Venous Insufficiency	24.7%
38	Peripheral Vascular Diseases	24.7%
39	Embolism and Thrombosis	24.7%
40	Angiodysplasia	24.7%
41	Capillary Leak Syndrome	24.7%
42	Prehypertension	24.7%
43	Hypoxia-Ischemia, Brain	24.3%
44	Fibromuscular Dysplasia	24.3%
45	Pulmonary artery stenosis	24.3%
46	Basal Ganglia Hemorrhage	24.2%
47	Cerebral Infarction	23.9%
48	Brain Stem Infarctions	23.9%
49	Subarachnoid Hemorrhage, Traumatic	23.6%
50	Intermittent Claudication	23.6%
51	Cerebral Thrombosis	23.5%
52	Intracranial Embolism	23.5%
53	Intracranial Thrombosis	23.5%
54	Aortic Aneurysm	23.5%
55	Aortitis	23.5%
56	Periphlebitis	23.5%
57	Phlebitis	23.5%
58	Vertebrobasilar Insufficiency	22.4%
59	Basilar Artery Stenosis	22.4%
60	Vertebral Artery Stenosis	22.4%
61	Intracranial Hemorrhage, Hypertensive	22.4%
62	Transient Cerebral Ischemia	22.4%
63	Retinal Vein Occlusion	21.5%
64	Carotid Artery, Internal, Dissection	21.1%
65	Thoracic Outlet Syndrome	20.7%
66	Vascular System Injuries	20.6%
67	Compartment syndromes	20.1%
68	Hepatic Veno-Occlusive Disease	20.1%
69	Peliosis Hepatis	20.1%
70	Varicocele	20.1%
71	Vertebral Artery Dissection	20%
72	Giant Cell Arteritis	19.9%
73	Temporal Arteritis	19.9%
74	Lateral Medullary Syndrome	19.8%
75	Diabetic Angiopathies	19.8%
76	Reperfusion Injury	19.8%
77	Retinal Artery Occlusion	19.8%
78	Splenic Infarction	19.8%
79	Vascular Neoplasms	19.8%
80	Vasoplegia	19.8%
81	Hemorrhoids	19.7%
82	Myocardial Reperfusion Injury	19.6%
83	Shwartzman Phenomenon	19.5%
84	Pituitary Apoplexy	19.5%
85	Postphlebitic Syndrome	19.4%
86	Putaminal Hemorrhage	18.8%
87	Subarachnoid Hemorrhage	18.7%
88	Cerebral Hemorrhage	18.7%
89	Hand-Arm Vibration Syndrome	18.5%
90	Coronary Aneurysm	18.3%
91	Optic Neuropathy, Ischemic	18.1%
92	Anterior Ischemic Optic Neuropathy	18.1%
93	Sinus Thrombosis, Intracranial	17.9%
94	Thrombophlebitis	17.6%
95	Dementia, Vascular	16.9%
96	Aortic Rupture	16.8%
97	Subclavian Steal Syndrome	16.7%
98	Mesenteric vascular insufficiency	16.7%
99	Mesenteric Vascular Occlusion	16.5%
100	Blue Toe Syndrome	16.4%
101	Angioedema	16.3%
102	Colitis, Ischemic	16.3%
103	Renal Artery Obstruction	16.3%
104	Renal Artery Stenosis	16.3%
105	Arteriovenous fistula	15.8%
106	Lupus Vasculitis, Central Nervous System	15.8%
107	Coronary heart disease	15.6%
108	Myocardial Infarction	15.6%
109	Acute Coronary Syndrome	15.6%
110	Aortic Aneurysm, Abdominal	15.4%
111	Aortic Aneurysm, Thoracic	15.4%
112	Heart Diseases	15.3%
113	Cavernous Sinus Thrombosis	15.1%
114	Sagittal Sinus Thrombosis	15.1%
115	Coronary Thrombosis	15%
116	Aneurysm, Dissecting	14.6%
117	Arteritis	14.6%
118	Embolism	14.6%
119	Erythromelalgia	14.6%
120	Malignant Hypertension	14.6%
121	Raynaud Disease	14.6%
122	Thromboembolism	14.6%
123	Thrombosis	14.6%
124	Essential Hypertension	14.6%
125	Aneurysm, Ruptured	14.6%
126	Iliac Aneurysm	14.6%
127	White Coat Hypertension	14.6%
128	Systemic Vasculitis	14.6%
129	Embolus	14.6%
130	Spinal Cord Ischemia	14.6%
131	Subdural Effusion	14.2%
132	Akinetic Mutism	14.2%
133	Anoxic Encephalopathy	14.2%
134	Basal Ganglia Diseases	14.2%
135	Brain Damage, Chronic	14.2%
136	Cerebellar Diseases	14.2%
137	Encephalitis	14.2%
138	Encephalomalacia	14.2%
139	Epilepsy	14.2%
140	Hydrocephalus	14.2%
141	Congenital Hydrocephalus	14.2%
142	Hypothalamic Diseases	14.2%
143	Thalamic Diseases	14.2%
144	Intracranial Hypertension	14.2%
145	Aura	14.2%
146	Leukoencephalopathy	14.2%
147	Neuroaxonal Dystrophies	14.2%
148	Headache Disorders	14.2%
149	Intracranial Hypotension	14.2%
150	Brain Edema	14.2%
151	Brain Hypoxia	14.2%
152	Aqueductal Stenosis	14.2%
153	Meningoencephalitis	13.9%
154	Encephalomyelitis	13.9%
155	Shy-Drager Syndrome	13.6%
156	Scimitar Syndrome	13.4%
157	Kounis Syndrome	13.2%
158	May-Thurner Syndrome	13%
159	Angina Pectoris	13%
160	Polyarteritis Nodosa	12.9%
161	Takayasu Arteritis	12.9%
162	Brain Hemorrhage, Traumatic	12.8%
163	Hypotension, Orthostatic	12.6%
164	Post-Exercise Hypotension	12.6%
165	Pregnancy Complications, Cardiovascular	12.4%
166	Cardiovascular Abnormalities	12.4%
167	Arterial Occlusive Diseases	12.3%
168	Sturge-Weber Syndrome	12.3%
169	Embolism, Amniotic Fluid	12.1%
170	Dandy-Walker Syndrome	11.9%
171	Pneumocephalus	11.9%
172	Retinal Vasculitis	11.9%
173	Hypertensive Retinopathy	11.9%
174	Brain Abscess	11.8%
175	Multiple System Atrophy	11.8%
176	Anterior Compartment Syndrome	11.7%
177	Vasculitis, Leukocytoclastic, Cutaneous	11.7%
178	Gastric Antral Vascular Ectasia	11.7%
179	Abdominal Compartment Syndrome	11.7%
180	Varicose Ulcer	11.7%
181	Parkinsonian Disorders	11.7%
182	Primary Graft Dysfunction	11.7%
183	Brain Diseases, Metabolic	11.6%
184	Dementia	11.6%
185	MELAS Syndrome	11.5%
186	Posterior Leukoencephalopathy Syndrome	11.2%
187	Posterior reversible encephalopathy syndrome	11.2%
188	Meningitis	11.1%
189	Movement Disorders	11.1%
190	Pachymeningitis	11.1%
191	Spinal Cord Diseases	11.1%
192	Brain Injuries	10.9%
193	Brain Neoplasms	10.8%
194	Lewy Body Disease	10.8%
195	CREST Syndrome	10.8%
196	Ocular Motility Disorders	10.4%
197	Cyclophoria	10.4%
198	Epilepsy, Post-Traumatic	10.3%
199	Coronary Occlusion	10.3%
200	Microvascular Angina	10.3%
201	Coronary Stenosis	10.3%
202	ST segment elevation myocardial infarction	10.3%
203	Mucocutaneous Lymph Node Syndrome	9.9%
204	Cerebrovascular Disorders	9.9%
205	Cerebrovascular Insufficiency	9.9%
206	Hematoma, Subdural	9.9%
207	Hematoma, Epidural, Cranial	9.9%
208	Diabetic Retinopathy	9.9%
209	Brain Death	9.9%
210	Marchiafava-Bignami Disease	9.8%
211	Livedo Reticularis	9.8%
212	Myelitis	9.8%
213	Renal hypertension	9.8%
214	Hemangioma, Cavernous	9.7%
215	Scurvy	9.7%
216	Meige Syndrome	9.6%
217	Cerebral Ventriculitis	9.6%
218	Air Embolism	9.6%
219	Endarteritis	9.6%
220	Venous Thrombosis	9.6%
221	Deep Vein Thrombosis	9.6%
222	Venous Thromboembolism	9.6%
223	Anterior Spinal Artery Syndrome	9.6%
224	Ataxia Telangiectasia	9.5%
225	Central Nervous System Infection	9.3%
226	Lemierre Syndrome	9.2%
227	Epidural Abscess	9%
228	Myoclonic Epilepsy	8.9%
229	Epilepsy, Temporal Lobe	8.9%
230	Epilepsy, Rolandic	8.9%
231	Benign Rolandic Epilepsy	8.9%
232	Amblyopia	8.9%
233	Parkinson Disease	8.7%
234	Huntington Disease	8.6%
235	Shock, Cardiogenic	8.6%
236	Angina, Unstable	8.5%
237	Cerebellar Neoplasms	8.4%
238	Cerebral Palsy	8.4%
239	Epilepsies, Partial	8.4%
240	Epilepsy, Generalized	8.4%
241	Pseudotumor Cerebri	8.4%
242	Hypertensive Encephalopathy	8.4%
243	Simple Partial Seizures	8.4%
244	Epilepsy, Reflex	8.4%
245	Headache Disorders, Primary	8.4%
246	Headache Disorders, Secondary	8.4%
247	Medication overuse headache	8.4%
248	Ischemic contracture	8.4%
249	Angioedemas, Hereditary	8.4%
250	Tricuspid Atresia	8.4%
251	Arrhythmogenic Right Ventricular Dysplasia	8.4%
252	Cryoglobulinemia	8.4%
253	Fabry Disease	8.3%
254	Diabetic Foot	8.3%
255	Cardiac Tamponade	8.2%
256	Endocarditis	8.2%
257	Cardiac Arrest	8.2%
258	Heart failure	8.2%
259	Pericardial effusion	8.2%
260	Pericarditis	8.2%
261	Pneumopericardium	8.2%
262	Cor pulmonale	8.2%
263	Ventricular Outflow Obstruction	8.2%
264	Ventricular Dysfunction	8.2%
265	Cardiomyopathies	8.2%
266	Pleuropericarditis	8.2%
267	Neuroleptic Malignant Syndrome	8.2%
268	Myelinolysis, Central Pontine	8.2%
269	Dystonia Musculorum Deformans	8.1%
270	Creutzfeldt-Jakob disease	8.1%
271	Hematoma, Subdural, Intracranial	8.1%
272	Hematoma, Subdural, Chronic	8.1%
273	Hematoma, Subdural, Acute	8.1%
274	Prion Diseases	7.9%
275	Stiff-Person Syndrome	7.9%
276	Pulmonary Embolism	7.9%
277	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.9%
278	Aortic Valve Stenosis	7.8%
279	Cardiomyopathy, Dilated	7.8%
280	Pulmonary Valve Stenosis	7.8%
281	No-Reflow Phenomenon	7.8%
282	Coronary Restenosis	7.7%
283	Bacterial Endocarditis	7.6%
284	Progressive supranuclear palsy	7.6%
285	Amnesia, Transient Global	7.5%
286	Arteriosclerosis	7.3%
287	Purpura, Hyperglobulinemic	7.3%
288	Cranial nerve diseases	7.2%
289	Demyelinating Diseases	7.2%
290	Demyelination	7.2%
291	Neuromuscular Diseases	7.2%
292	Chronobiology Disorders	7.2%
293	Leukoencephalopathy, Progressive Multifocal	7.2%
294	Striatonigral Degeneration	7.1%
295	Limbic Encephalitis	7.1%
296	Pituitary Diseases	7.1%
297	Presenile dementia	7%
298	Senile dementia	7%
299	Spinal Cord Injuries	6.8%
300	Subacute Combined Degeneration	6.8%
301	Spinal Muscular Atrophy	6.8%
302	Progressive Muscular Atrophy	6.8%
303	Kluver-Bucy Syndrome	6.8%
304	Cardiac Output, High	6.7%
305	Myocardial Stunning	6.7%
306	Low Cardiac Output Syndrome	6.7%
307	Juvenile Myoclonic Epilepsy	6.7%
308	Myoclonic Epilepsies, Progressive	6.7%
309	Asterixis	6.6%
310	Ballismus	6.6%
311	Cardiomegaly	6.6%
312	Postpericardiotomy Syndrome	6.6%
313	Cardiac Hypertrophy	6.6%
314	Behcet Syndrome	6.6%
315	Heart Block	6.5%
316	Tachycardia	6.5%
317	Tachyarrhythmia	6.5%
318	Rheumatic Heart Disease	6.5%
319	Waldenstrom Macroglobulinemia	6.5%
320	Multiple Myeloma	6.5%
321	Aortic coarctation	6.5%
322	Cor Triatriatum	6.5%
323	Coronary Vessel Anomalies	6.5%
324	Patent ductus arteriosus	6.5%
325	Ebstein Anomaly	6.5%
326	Heart Septal Defects	6.5%
327	Tetralogy of Fallot	6.5%
328	Transposition of Great Vessels	6.5%
329	Meningitis, Bacterial	6.5%
330	Meningitis, Fungal	6.5%
331	Hypoplastic Left Heart Syndrome	6.5%
332	Brain Injuries, Diffuse	6.4%
333	Traumatic Brain Injury	6.4%
334	Cerebellar Ataxia	6.4%
335	Intracranial Arteriosclerosis	6.4%
336	Cerebral Atherosclerosis	6.4%
337	Hypertension, Renovascular	6.4%
338	Supratentorial Neoplasms	6.4%
339	Cerebral Arteriosclerosis	6.4%
340	Hepatolenticular Degeneration	6.4%
341	Hereditary Angioedema Type III	6.4%
342	Hereditary Angioedema Types I and II	6.4%
343	Angina Pectoris, Variant	6.4%
344	Poliomyelitis	6.3%
345	Amyotrophic Lateral Sclerosis	6.1%
346	Persistent Vegetative State	6.1%
347	Arachnoiditis	6.1%
348	Aseptic Meningitis	6.1%
349	Syringomyelia	6.1%
350	Essential Tremor	6.1%
351	Familial Tremor	6.1%
352	Pneumorrhachis	6.1%
353	Writer's Cramp	6.1%
354	Paraneoplastic Cerebellar Degeneration	6%
355	Motor Neuron Disease	6%
356	Trauma, Nervous System	6%
357	Pseudoxanthoma Elasticum	6%
358	MPTP Poisoning	5.9%
359	Leukoencephalitis, Acute Hemorrhagic	5.9%
360	Pituitary Adenoma	5.9%
361	Pituitary Neoplasms	5.9%
362	Chronic Fatigue Syndrome	5.9%
363	Hepatic Vein Thrombosis	5.9%
364	Budd-Chiari Syndrome	5.9%
365	Nervous System Neoplasms	5.8%
366	Neurologic Manifestations	5.8%
367	Neurotoxicity Syndromes	5.8%
368	Intracranial Arterial Diseases	5.8%
369	Toxoplasmosis, Cerebral	5.8%
370	Hypertrophic Cardiomyopathy	5.8%
371	Pulmonary Infarction	5.8%
372	Hypertrophic obstructive cardiomyopathy	5.8%
373	Reye Syndrome	5.7%
374	Hepatic Encephalopathy	5.7%
375	Ophthalmoplegic Migraine	5.7%
376	Post-Traumatic Headache	5.6%
377	Tension Headache	5.6%
378	Epilepsy, Complex Partial	5.6%
379	Migraine Disorders	5.6%
380	Abdominal Migraine	5.6%
381	Status Migrainosus	5.6%
382	Cervicogenic Headache	5.6%
383	Dextrocardia	5.6%
384	Long QT Syndrome	5.6%
385	Encephalomyelitis, Acute Disseminated	5.6%
386	Spinal Cord Neoplasms	5.4%
387	Miller Fisher Syndrome	5.4%
388	Friedreich Ataxia	5.2%
389	Restless Legs Syndrome	5.2%
390	Lafora Disease	5.2%
391	Unverricht-Lundborg Syndrome	5.2%
392	Supravalvular aortic stenosis	5.1%
393	Lown-Ganong-Levine Syndrome	5.1%
394	Canavan Disease	5.1%
395	Alexander Disease	5.1%
396	Polyradiculoneuropathy	5%
397	Polyradiculoneuritis	5%
398	Akathisia, Drug-Induced	5%
399	Sleep Wake Disorders	5%
400	Central Nervous System Fungal Infections	5%
401	Conus Medullaris Syndrome	5%
402	Dural Arteriovenous Fistula	4.9%
403	Brain Diseases, Metabolic, Inborn	4.9%
404	Myelitis, Transverse	4.9%
405	Mitochondrial Encephalomyopathies	4.9%
406	Rheumatoid Vasculitis	4.9%
407	Granulomatosis with polyangiitis	4.9%
408	Aortic Valve Insufficiency	4.9%
409	Restrictive cardiomyopathy	4.9%
410	Endocardial Fibroelastosis	4.9%
411	Heart Rupture, Post-Infarction	4.9%
412	Mitral Valve Insufficiency	4.9%
413	Mitral Valve Stenosis	4.9%
414	Myocarditis	4.9%
415	Pericarditis, Constrictive	4.9%
416	Pulmonary Valve Insufficiency	4.9%
417	Tricuspid Valve Insufficiency	4.9%
418	Tricuspid Valve Stenosis	4.9%
419	Ventricular Dysfunction, Left	4.9%
420	Right Ventricular Dysfunction	4.9%
421	Endomyocardial Fibrosis	4.9%
422	Carditis	4.9%
423	Heart Failure, Systolic	4.9%
424	Heart Failure, Diastolic	4.9%
425	Sick Sinus Syndrome	4.8%
426	Autonomic Dysreflexia	4.6%
427	Complex Regional Pain Syndromes	4.6%
428	Opsoclonus-Myoclonus Syndrome	4.6%
429	Carcinoid Heart Disease	4.6%
430	Empty Sella Syndrome	4.6%
431	Hyperpituitarism	4.6%
432	Hypopituitarism	4.6%
433	Hypophysitis	4.6%
434	Noonan Syndrome	4.4%
435	Auditory Perceptual Disorders	4.3%
436	Adams-Stokes Syndrome	4.3%
437	Atrioventricular Block	4.3%
438	Bundle-Branch Block	4.3%
439	Atrial Premature Complexes	4.3%
440	Sinoatrial Block	4.3%
441	Tachycardia, Paroxysmal	4.3%
442	Supraventricular tachycardia	4.3%
443	Tachycardia, Ventricular	4.3%
444	Wolff-Parkinson-White Syndrome	4.3%
445	Tachycardia, Reciprocating	4.3%
446	Aortopulmonary Septal Defect	4.3%
447	Double Outlet Right Ventricle	4.3%
448	Endocardial Cushion Defects	4.3%
449	Myocardial bridging	4.3%
450	Aorticopulmonary Septal Defect	4.3%
451	Wernicke Encephalopathy	4.3%
452	Diffuse Axonal Injury	4.3%
453	AIDS Dementia Complex	4.3%
454	Brain Stem Neoplasms	4.2%
455	Dyskinesia, Drug-Induced	4.2%
456	Tuberculosis, Meningeal	4.2%
457	Cluster Headache	4.2%
458	Migraine with Aura	4.2%
459	Familial Hemiplegic Migraine	4.2%
460	Chronic Paroxysmal Hemicrania	4.2%
461	SUNCT Syndrome	4.2%
462	Paroxysmal Hemicrania	4.2%
463	Central Nervous System Bacterial Infections	4.2%
464	Subacute Bacterial Endocarditis	4.1%
465	Marfan Syndrome	4%
466	Sinus Arrhythmia	3.9%
467	Atrial Fibrillation	3.9%
468	Atrial Flutter	3.9%
469	Edema, Cardiac	3.9%
470	Ventricular Fibrillation	3.9%
471	Ventricular Flutter	3.9%
472	Parasystole	3.9%
473	Paroxysmal atrial fibrillation	3.9%
474	Bradycardia	3.9%
475	Diabetic Cardiomyopathies	3.9%
476	Peripheral Nerve Injuries	3.9%
477	Frontotemporal dementia	3.9%
478	Cardiomyopathy, Alcoholic	3.9%
479	Ectopia Cordis	3.9%
480	Sudden Cardiac Death	3.9%
481	Left Ventricular Hypertrophy	3.9%
482	Right Ventricular Hypertrophy	3.9%
483	Single umbilical artery	3.9%
484	Chagas Cardiomyopathy	3.9%
485	Myasthenia Gravis	3.9%
486	Kernicterus	3.9%
487	Adrenoleukodystrophy	3.8%
488	Scrapie	3.8%
489	Central Cord Syndrome	3.8%
490	Chorea	3.8%
491	Dysautonomia	3.7%
492	Vagus Nerve Disorder	3.7%
493	Glossopharyngeal Neuralgia	3.7%
494	Abducens Nerve Diseases	3.7%
495	Heavy Metal Poisoning, Nervous System	3.7%
496	Neuromuscular Junction Diseases	3.7%
497	Tauopathies	3.7%
498	Trochlear Nerve Diseases	3.7%
499	Peripheral Nervous System Diseases	3.7%
500	Subacute Sclerosing Panencephalitis	3.7%
501	Romano-Ward Syndrome	3.7%
502	Brain Contusion	3.7%
503	Lambert-Eaton Myasthenic Syndrome	3.5%
504	Meningitis, Cryptococcal	3.5%
505	Guillain-Barre Syndrome	3.5%
506	Meningitis, Listeria	3.4%
507	Meningitis, Haemophilus	3.4%
508	Meningitis, Pneumococcal	3.4%
509	Sleep Disorders, Circadian Rhythm	3.4%
510	Brain Concussion	3.4%
511	Hyperprolactinemia	3.4%
512	Pick Disease of the Brain	3.3%
513	Botulism	3.3%
514	Central Nervous System Cysts	3.3%
515	Progressive bulbar palsy	3.3%
516	Bulbar palsy	3.3%
517	Dyspnea, Paroxysmal	3.3%
518	Aortic Valve Prolapse	3.2%
519	Tricuspid Valve Prolapse	3.2%
520	Takotsubo Cardiomyopathy	3.2%
521	Torticollis	3.2%
522	Tachycardia, Atrioventricular Nodal Reentry	3.2%
523	Tachycardia, Ectopic Atrial	3.2%
524	Tachycardia, Ectopic Junctional	3.2%
525	Sinus Tachycardia	3.2%
526	Torsades de Pointes	3.2%
527	Accelerated Idioventricular Rhythm	3.2%
528	Truncus Arteriosus, Persistent	3.2%
529	Choroid Plexus Papilloma	3.2%
530	Myopathy	3.1%
531	Optic Neuropathy	3.1%
532	Olfactory Nerve Injuries	3%
533	Facial Nerve Diseases	3%
534	Craniocerebral Trauma	3%
535	Parasomnia	3%
536	Dyssomnias	3%
537	Vestibulocochlear Nerve Diseases	3%
538	Decerebrate State	3%
539	Hemiparesis	3%
540	Hydranencephaly	3%
541	Meningism	3%
542	Neural Tube Defects	3%
543	Paresis	3%
544	Seizures	3%
545	Sensation Disorders	3%
546	Tethered Cord Syndrome	3%
547	Central Nervous System Neoplasms	3%
548	Complex partial seizures	3%
549	Iniencephaly	3%
550	Craniorachischisis	3%
551	Exencephaly	3%
552	Monoparesis	3%
553	Septo-Optic Dysplasia	3%
554	Cortical Dysplasia	3%
555	Neurogenic Inflammation	3%
556	Gait Disorders, Neurologic	3%
557	Neuromuscular Manifestations	3%
558	Malformations of Cortical Development	3%
559	Causalgia	3%
560	Sweating, Gustatory	3%
561	Auriculotemporal Syndrome	3%
562	Alice in Wonderland Syndrome	2.9%
563	Tuberculosis, Central Nervous System	2.9%
564	Acromegaly	2.8%
565	Horner Syndrome	2.8%
566	Neuromyelitis Optica	2.8%
567	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.8%
568	Refsum Disease	2.8%
569	Multiple Sclerosis	2.7%
570	Facial Nerve Injuries	2.6%
571	West Nile Fever	2.6%
572	Reflex Sympathetic Dystrophy	2.6%
573	Nocturnal Myoclonus Syndrome	2.6%
574	Sinus Arrest, Cardiac	2.6%
575	Pupil Disorders	2.6%
576	Neurobehavioral Manifestations	2.6%
577	Paraneoplastic Encephalomyelitis	2.5%
578	Galactosemias	2.5%
579	Urea Cycle Disorders, Inborn	2.5%
580	Tyrosinemias	2.5%
581	Uveomeningoencephalitic Syndrome	2.5%
582	Vertigo	2.5%
583	Alcohol-Induced Disorders, Nervous System	2.5%
584	Jet Lag Syndrome	2.5%
585	Neuroaspergillosis	2.4%
586	Turner Syndrome	2.4%
587	Tardive Dyskinesia	2.4%
588	Tuberous Sclerosis	2.4%
589	Ophthalmoplegia	2.4%
590	External Ophthalmoplegia	2.4%
591	Myasthenia Gravis, Autoimmune, Experimental	2.3%
592	Homocystinuria	2.3%
593	Leigh Disease	2.3%
594	Kearns-Sayre syndrome	2.2%
595	Pseudorabies	2.2%
596	Voice Disorders	2.2%
597	Voice Disturbance	2.2%
598	Acrodynia	2.2%
599	Smith-Magenis syndrome	2.1%
600	Prolactinoma	2.1%
601	Growth Hormone-Secreting Pituitary Adenoma	2.1%
602	Williams Syndrome	2.1%
603	Vocal Cord Paralysis	2.1%
604	Neurosyphilis	2.1%
605	Neuritis	2%
606	Polyneuritis	2%
607	Radiculitis	2%
608	Polyneuropathy	2%
609	Mononeuritis	2%
610	Mononeuropathies	2%
611	Brachial Plexus Neuropathies	2%
612	Radiculopathy	2%
613	Mononeuropathy Multiplex	2%
614	Nerve Root Compression	2%
615	Charcot-Marie-Tooth Disease	2%
616	Nelson Syndrome	2%
617	Menkes Kinky Hair Syndrome	2%
618	Brachial Plexus Neuritis	1.9%
619	Neuralgic Amyotrophy	1.9%
620	Myotonia Congenita	1.9%
621	Cerebrospinal Fluid Otorrhea	1.8%
622	Cerebrospinal Fluid Rhinorrhea	1.8%
623	Neuritis, Autoimmune, Experimental	1.8%
624	Gait Ataxia	1.8%
625	Reflex, Abnormal	1.8%
626	Hyporeflexia	1.8%
627	Hyperreflexia	1.8%
628	Lyme Neuroborreliosis	1.8%
629	Alcohol Withdrawal Seizures	1.8%
630	Kartagener Syndrome	1.8%
631	Zellweger Syndrome	1.8%
632	Coma, Post-Head Injury	1.8%
633	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.7%
634	Myositis	1.7%
635	Optic Atrophy	1.7%
636	Optic Neuritis	1.7%
637	Papilledema	1.7%
638	Strabismus	1.7%
639	Tolosa-Hunt Syndrome	1.7%
640	Isaacs syndrome	1.7%
641	Arsenic Poisoning	1.7%
642	Myotonic Disorders	1.7%
643	Myasthenic Syndromes, Congenital	1.7%
644	Toxoplasmosis, Congenital	1.6%
645	Diabetic Neuropathies	1.6%
646	Facial Injuries	1.6%
647	Facial Neuralgia	1.6%
648	Myotonic Dystrophy	1.6%
649	Diabetic Amyotrophy	1.6%
650	Diabetic Autonomic Neuropathy	1.6%
651	Sleep Talking	1.6%
652	Manganese Poisoning	1.6%
653	Sleep Disorders, Intrinsic	1.6%
654	Orthostatic intolerance	1.6%
655	Malaria, Cerebral	1.6%
656	Akathisia	1.6%
657	Restlessness	1.6%
658	Psychomotor Agitation	1.6%
659	Anosmia	1.6%
660	Ataxia	1.6%
661	Athetosis	1.6%
662	Catalepsy	1.6%
663	Dystonia	1.6%
664	Hemiplegia	1.6%
665	Locked-In Syndrome	1.6%
666	Meningeal Neoplasms	1.6%
667	Meningomyelocele	1.6%
668	Muscle Hypertonia	1.6%
669	Muscle hypotonia	1.6%
670	Myoclonus	1.6%
671	Myotonia	1.6%
672	Neuralgia	1.6%
673	Paraplegia	1.6%
674	Pseudobulbar Palsy	1.6%
675	Quadriplegia	1.6%
676	Spasm	1.6%
677	Spastic Paraplegia	1.6%
678	Status Epilepticus	1.6%
679	Taste Disorders	1.6%
680	Tremor	1.6%
681	Spina Bifida	1.6%
682	Monoplegia	1.6%
683	Hypokinesia	1.6%
684	Paraparesis	1.6%
685	Bradykinesia	1.6%
686	Waxy flexibility	1.6%
687	Action Tremor	1.6%
688	Resting Tremor	1.6%
689	Dysosmia	1.6%
690	Quadriparesis	1.6%
691	Mercury Poisoning, Nervous System	1.6%
692	Olfaction Disorders	1.6%
693	Myokymia	1.6%
694	Lead Poisoning, Nervous System	1.6%
695	Vestibular Neuronitis	1.6%
696	Somatosensory Disorders	1.6%
697	Neuropathic pain	1.6%
698	Hyperkinesia	1.6%
699	Intention tremor	1.6%
700	Neurocysticercosis	1.6%
701	Multiple Sclerosis, Chronic Progressive	1.6%
702	Multiple Sclerosis, Relapsing-Remitting	1.6%
703	Tarsal Tunnel Syndrome	1.6%
704	Cauda Equina Syndrome	1.6%
705	Glycogen storage disease type II	1.5%
706	Waterhouse-Friderichsen Syndrome	1.4%
707	Gait Apraxia	1.4%
708	Vision Disorders	1.4%
709	Metamorphopsia	1.4%
710	Visual Impairment	1.4%
711	Fibromyalgia	1.4%
712	Medial Tibial Stress Syndrome	1.4%
713	Facial Hemiatrophy	1.4%
714	Melkersson-Rosenthal Syndrome	1.4%
715	Mitochondrial Myopathies	1.4%
716	Anisocoria	1.4%
717	Confusion	1.4%
718	Facial paralysis	1.4%
719	Lethargy	1.4%
720	Memory Disorders	1.4%
721	Muscle Cramp	1.4%
722	Perceptual Disorders	1.4%
723	Psychomotor Disorders	1.4%
724	Tonic Pupil	1.4%
725	Eosinophilia-Myalgia Syndrome	1.4%
726	Anhedonia	1.4%
727	Disorientation	1.4%
728	Facial Paresis	1.4%
729	Memory Loss	1.4%
730	Hemisensory Neglect	1.4%
731	Dysacusis	1.4%
732	Sleep Bruxism	1.4%
733	Anencephaly	1.4%
734	Meningocele	1.4%
735	Muscular Atrophy	1.4%
736	Respiratory Paralysis	1.4%
737	Encephalocele	1.4%
738	Optic Nerve Glioma	1.4%
739	Alstrom Syndrome	1.4%
740	Acoustic Neuroma	1.4%
741	Tetany	1.3%
742	Carpal Tunnel Syndrome	1.3%
743	neurofibroma	1.3%
744	Sciatica	1.3%
745	Amyloid Neuropathies, Familial	1.3%
746	Sciatic Neuropathy	1.2%
747	Ulnar Neuropathies	1.2%
748	Lesion of Sciatic Nerve	1.2%
749	Ulnar Neuritis	1.2%
750	Radial nerve compression	1.2%
751	Radial Tunnel Syndrome	1.2%
752	Peroneal Neuropathies	1.2%
753	Radial Neuropathy	1.2%
754	Median Neuropathy	1.2%
755	Sciatic Nerve Palsy	1.2%
756	Femoral Neuropathy	1.2%
757	Tibial Neuropathy	1.2%
758	Ulnar Nerve Palsy	1.2%
759	Postural Orthostatic Tachycardia Syndrome	1.2%
760	Radial nerve palsy	1.2%
761	Duane Retraction Syndrome	1.2%
762	Consciousness Disorders	1.2%
763	Mental Retardation	1.2%
764	Muscle Weakness	1.2%
765	Depressed Level of Consciousness	1.2%
766	Mental deficiency	1.2%
767	Intellectual Disability	1.2%
768	Mobius Syndrome	1.2%
769	Bell Palsy	1.2%
770	Catatonia	1.2%
771	Herpes Zoster Oticus	1.2%
772	Familial Periodic Paralysis	1.2%
773	Aphonia	1.2%
774	Sleep Deprivation	1.2%
775	Dysphonia	1.2%
776	Gaucher Disease	1.2%
777	Cubital Tunnel Syndrome	1.1%
778	Myalgia	1%
779	Neuronal Ceroid-Lipofuscinoses	1%
780	Classical Lissencephalies and Subcortical Band Heterotopias	1%
781	Tay-Sachs Disease	1%
782	Esotropia	1%
783	Exotropia	1%
784	Sleep Apnea Syndromes	1%
785	Polymyositis	1%
786	Disorders of Excessive Somnolence	1%
787	Sleep Initiation and Maintenance Disorders	1%
788	Night Terrors	1%
789	Somnambulism	1%
790	Trigeminal Nerve Disorder	1%
791	Transient Insomnia	1%
792	Sleep Paralysis	1%
793	Chronic Insomnia	1%
794	REM Sleep Behavior Disorder	1%
795	Hypersomnia	1%
796	Dermal Sinus	1%
797	Dysgeusia	1%
798	Formication	1%
799	Hyperalgesia	1%
800	Hyperesthesia	1%
801	Hypesthesia	1%
802	Language Disorders	1%
803	Numbness	1%
804	Paresthesia	1%
805	Paraparesis, Spastic	1%
806	Spina Bifida Cystica	1%
807	Trismus	1%
808	Spina Bifida Occulta	1%
809	Epilepsia Partialis Continua	1%
810	Hypogeusia	1%
811	Meningeal Carcinomatosis	1%
812	Brown-Sequard Syndrome	1%
813	Lissencephaly	1%
814	Polymicrogyria	1%
815	Pachygyria	1%
816	Schizencephaly	1%
817	Lockjaw	1%
818	Allodynia	1%
819	Lead Poisoning, Nervous System, Childhood	1%
820	Lead Poisoning, Nervous System, Adult	1%
821	Periventricular Nodular Heterotopia	1%
822	Ageusia	1%
823	Niemann-Pick Disease, Type C	1%
824	Aicardi's syndrome	0.9%
825	Hoarseness	0.9%
826	Cockayne Syndrome	0.9%
827	Alcohol Withdrawal Delirium	0.9%
828	Eye Injuries	0.8%
829	Muscular Dystrophy	0.8%
830	Congenital nystagmus	0.8%
831	Orbital Myositis	0.8%
832	Holoprosencephaly	0.8%
833	Diplopia	0.8%
834	Muscle Rigidity	0.8%
835	Muscle Spasticity	0.8%
836	Scotoma	0.8%
837	Photophobia	0.8%
838	Cogwheel Rigidity	0.8%
839	Hemifacial Spasm	0.8%
840	Amaurosis	0.8%
841	Blindness	0.8%
842	Nuchal Rigidity	0.8%
843	Pyomyositis	0.8%
844	Optic Atrophy, Hereditary, Leber	0.8%
845	Agnosia	0.8%
846	Apraxias	0.8%
847	Hallucinations	0.8%
848	Hemianopsia	0.8%
849	Hyperacusis	0.8%
850	Tinnitus	0.8%
851	Visual Agnosia	0.8%
852	Anosognosia	0.8%
853	Wernicke-Korsakoff Syndrome	0.8%
854	Phonophobia	0.8%
855	Hearing Loss	0.8%
856	Sarcopenia	0.8%
857	Alexia	0.8%
858	Polyradiculopathy	0.8%
859	Dyslexia	0.8%
860	Amnesia	0.7%
861	Delirium	0.7%
862	Dissociative Amnesia	0.7%
863	Color blindness	0.7%
864	Global Amnesia	0.7%
865	Cri-du-Chat Syndrome	0.7%
866	Down Syndrome	0.7%
867	Trisomy 21	0.7%
868	POEMS Syndrome	0.7%
869	Neurofibrosarcoma	0.7%
870	Meningioma	0.7%
871	Microcephaly	0.7%
872	Macrocephaly	0.7%
873	Hypokalemic periodic paralysis	0.7%
874	Porencephaly	0.7%
875	Sleep Apnea, Obstructive	0.6%
876	Sleep Apnea, Central	0.6%
877	Narcolepsy	0.6%
878	Trigeminal Neuralgia	0.6%
879	Kleine-Levin Syndrome	0.6%
880	Agraphia	0.6%
881	Anomia	0.6%
882	Cluttering	0.6%
883	Language Development Disorders	0.6%
884	Speech Disorders	0.6%
885	Syncope	0.6%
886	Stupor	0.6%
887	Dysgraphia	0.6%
888	Presyncope	0.6%
889	Dyslalia	0.6%
890	Prader-Willi Syndrome	0.6%
891	Phantom pain	0.6%
892	Phantom Limb Pain	0.6%
893	Eye Burns	0.5%
894	Welander Distal Myopathy	0.5%
895	Amaurosis Fugax	0.5%
896	Blindness, Cortical	0.5%
897	Dyscalculia	0.5%
898	Rett Syndrome	0.5%
899	Deafness	0.5%
900	Hearing Loss, Sudden	0.5%
901	Gerstmann Syndrome	0.5%
902	Hearing Loss, Bilateral	0.5%
903	Hearing Loss, High-Frequency	0.5%
904	Hearing Loss, Mixed Conductive-Sensorineural	0.5%
905	Prosopagnosia	0.5%
906	Apraxia, Ideomotor	0.5%
907	Charles Bonnet Syndrome	0.5%
908	Hearing Loss, Unilateral	0.5%
909	Complete Hearing Loss	0.5%
910	Alien Hand Syndrome	0.5%
911	Deaf Mutism	0.5%
912	Rubinstein-Taybi Syndrome	0.5%
913	Cataplexy	0.5%
914	Aphasia	0.5%
915	Articulation Disorders	0.5%
916	Echolalia	0.5%
917	Stuttering	0.5%
918	Dysphasia	0.5%
919	Dermatomyositis	0.5%
920	Corneal Scar	0.5%
921	Muscular Dystrophy, Duchenne	0.5%
922	Retrograde amnesia	0.5%
923	Amnesia, Anterograde	0.5%
924	Mutism	0.4%
925	Selective Mutism	0.4%
926	Fragile X Syndrome	0.4%
927	Dysarthria	0.4%
928	Corneal Perforation	0.3%
929	Alexia, Pure	0.3%
930	Mucopolysaccharidosis II	0.3%

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