MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

(UMLS:C0023485)

Definition:: A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.
UMLS ID:: C0023485
MeSH ID:: D015452

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.337.428.600.600

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.515.560.600.600

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.683.515.528.600.600

Synonym(s)

Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Pre-B Acute Lymphoblastic Leukemia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Cyclophosphamide	18191947 21064136	CTD
2	Cytarabine	View details 8083715 11070476 17207701 18176182 18191947 21064136	CTD
3	Daunorubicin	21064136	CTD
4	Dexamethasone	18176182 18191947 24154679	CTD
5	Doxorubicin	18191947	CTD
6	Hydrocortisone	21064136	CTD
7	Mercaptopurine	18176182 21064136	CTD
8	Methotrexate	View details 8083715 9586883 11070476 15749798 15933817 16786587 17207701 18176182 18191947 19736586 21064136	CTD
9	Prednisolone	18191947	CTD
10	Prednisone	11070476 21064136	CTD
11	Resveratrol	19796711	CTD
12	Vincristine	View details 16816519 17710662 18176182 18191947 21064136 21225912 24154679	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	49.2%
2	Leukemia, T-Cell	36%
3	Leukemia, B-Cell	36%
4	Lymphoma	26.6%
5	Leukemia, Large Granular Lymphocytic	23.8%
6	Tumor Lysis Syndrome	22.7%
7	Autoimmune Lymphoproliferative Syndrome	18.8%
8	Sezary Syndrome	18.4%
9	Leukemia, Plasma Cell	17.4%
10	Infectious Mononucleosis	17.4%
11	Composite Lymphoma	16.6%
12	Plasmacytoma	16.2%
13	Hodgkin Disease	15.3%
14	Lymphoma, Non-Hodgkin	15.3%
15	Primary amyloidosis	15.1%
16	Heavy Chain Disease	14.3%
17	Sarcoidosis	14.1%
18	Histiocytic Disorders, Malignant	13.8%
19	Lymphangioleiomyomatosis	13.7%
20	Agammaglobulinemia	13.4%
21	Waldenstrom Macroglobulinemia	12.8%
22	Multiple Myeloma	12.8%
23	Leukemia, Experimental	12%
24	Lymphocele	12%
25	Granuloma	11.5%
26	Adenitis	11%
27	Histiocytosis	11%
28	Lymphadenitis	11%
29	Lymphangitis	11%
30	Lymphedema	11%
31	Neoplasms, Germ Cell and Embryonal	11%
32	Neoplasms, Glandular and Epithelial	11%
33	Splenic Diseases	11%
34	Thymus Hyperplasia	11%
35	Pseudolymphoma	11%
36	Lymphadenopathy	11%
37	Germ Cell Cancer	11%
38	Paraproteinemias	10.5%
39	Thymus Neoplasms	10.5%
40	Leukemia, Radiation-Induced	10.4%
41	Lymphoma, Follicular	9.8%
42	T-Cell Lymphoma	9.8%
43	Mantle cell lymphoma	9.8%
44	Neuroectodermal Tumors	9.7%
45	Sarcoma, Myeloid	9.6%
46	Lymphatic Abnormalities	9%
47	Thymoma	8.9%
48	Transfusion Reaction	8.9%
49	Hypotensive Transfusion Reaction	8.9%
50	Hypergammaglobulinemia	8.9%
51	Neoplasms, Neuroepithelial	8.8%
52	Gliomatosis cerebri	8.8%
53	Leukemia L1210	8.4%
54	Leukemia P388	8.4%
55	Monoclonal Gammopathy of Undetermined Significance	8.3%
56	Lymphomatoid Granulomatosis	8.3%
57	Lymphangiectasis, Intestinal	8.1%
58	Splenic Neoplasms	7.9%
59	Carcinosarcoma	7.7%
60	Hemangiosarcoma	7.7%
61	Malignant histiocytosis	7.7%
62	lymphangiosarcoma	7.7%
63	Histiocytic sarcoma	7.7%
64	Leukemia, Myelomonocytic, Chronic	7.7%
65	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.7%
66	Mucocutaneous Lymph Node Syndrome	7.4%
67	Meningioma	7.4%
68	melanoma	7.2%
69	Autoimmune Diseases	7.2%
70	Hamartoma	7.2%
71	Hypersensitivity	7.2%
72	Immunologic Deficiency Syndromes	7.2%
73	Neoplasms, Hormone-Dependent	7.2%
74	Neoplasms, Multiple Primary	7.2%
75	Paraneoplastic Syndromes	7.2%
76	Precancerous Conditions	7.2%
77	Neoplasms, Second Primary	7.2%
78	Immune reconstitution syndrome	7.2%
79	Immune Reconstitution Inflammatory Syndrome	7.2%
80	Lymphoma, T-Cell, Cutaneous	7.1%
81	Lymphoma, AIDS-Related	7.1%
82	Enteropathy-Associated T-Cell Lymphoma	7.1%
83	Primary Effusion Lymphoma	7.1%
84	Sarcoidosis, Pulmonary	6.8%
85	Trophoblastic Neoplasms	6.6%
86	Carcinoma 256, Walker	6.5%
87	Adenoma	6%
88	Ameloblastoma	6%
89	Angiokeratoma	6%
90	Carcinoma	6%
91	Chordoma	6%
92	Elephantiasis	6%
93	Hemangioma	6%
94	hemangiopericytoma	6%
95	Hypersplenism	6%
96	Lymphangioma	6%
97	Mesenchymoma	6%
98	Nevus	6%
99	Teratoma	6%
100	Hepatoblastoma	6%
101	Mixed Tumor, Mullerian	6%
102	Germinoma	6%
103	Teratocarcinoma	6%
104	Angiofibroma	6%
105	Elephantiasis Nostras Verrucosa	6%
106	Sarcoma	6%
107	Epithelioma	6%
108	Hematologic Neoplasms	6%
109	Carcinoma, Ehrlich Tumor	5.9%
110	Dermoid Cyst	5.9%
111	Carcinoma, Lewis Lung	5.9%
112	Cyst	5.8%
113	Neoplastic Processes	5.8%
114	Neoplastic Syndromes, Hereditary	5.8%
115	Pregnancy Complications, Neoplastic	5.8%
116	Mycosis Fungoides	5.8%
117	Lymphomatoid Papulosis	5.8%
118	Plasmablastic lymphoma	5.8%
119	Basal cell carcinoma	5.8%
120	Carcinoma, Papillary	5.8%
121	Squamous cell carcinoma	5.8%
122	Chondrosarcoma	5.8%
123	Craniopharyngioma	5.8%
124	Cystadenoma	5.8%
125	leiomyosarcoma	5.8%
126	liposarcoma	5.8%
127	Mesothelioma	5.8%
128	synovial sarcoma	5.8%
129	Neuroectodermal Tumor, Melanotic	5.8%
130	Angiomyolipoma	5.8%
131	Clear Cell Sarcoma of Soft Tissue	5.8%
132	Alveolar Soft Part Sarcoma	5.8%
133	Neuroendocrine Tumors	5.8%
134	Carcinoma, Basal Cell	5.8%
135	Neoplasms, Experimental	5.7%
136	Adenoma, Acidophil	5.6%
137	Ganglioneuroma	5.6%
138	Glioma	5.6%
139	Malignant Glioma	5.6%
140	Melanoma, Experimental	5.4%
141	Burkitt Lymphoma	5.4%
142	Medulloblastoma	5.3%
143	Leukemia, Myeloid, Chronic-Phase	5.1%
144	Splenic Infarction	4.9%
145	Sarcoma, Experimental	4.9%
146	Histiocytosis, Langerhans-Cell	4.9%
147	Cryoglobulinemia	4.8%
148	Multiple Endocrine Neoplasia	4.8%
149	Neoplasms, Radiation-Induced	4.8%
150	Endometrial Stromal Sarcoma	4.8%
151	Cystadenocarcinoma	4.8%
152	Fibrosarcoma	4.8%
153	Osteosarcoma	4.8%
154	Mucoepidermoid Carcinoma	4.8%
155	Carcinoid Tumor	4.8%
156	Neurilemmoma	4.8%
157	Hutchinson's Melanotic Freckle	4.8%
158	Melanoma, Amelanotic	4.8%
159	Glomerulonephritis, Membranoproliferative	4.7%
160	Choriocarcinoma	4.6%
161	Carcinoma, Lobular	4.6%
162	Thrombocytopenic purpura	4.5%
163	Acanthoma	4.5%
164	Autoimmune thrombocytopenia	4.3%
165	Immune thrombocytopenic purpura	4.3%
166	Adenofibroma	4.3%
167	Fibroadenoma	4.3%
168	Malignant Fibrous Histiocytoma	4.3%
169	POEMS Syndrome	4.2%
170	Splenic Rupture	4.2%
171	Disseminated Intravascular Coagulation	4.1%
172	Protein S Deficiency	4.1%
173	Bone Marrow Neoplasms	4.1%
174	Astrocytoma	4%
175	Ependymoma	4%
176	oligodendroglioma	4%
177	Ganglioglioma	4%
178	gliosarcoma	4%
179	Anaplastic astrocytoma	4%
180	Anaplastic Oligodendroglioma	4%
181	Lymphopenia	3.9%
182	Retinoblastoma	3.9%
183	Paraneoplastic Encephalomyelitis	3.9%
184	Nephroblastoma	3.8%
185	Mammary Neoplasms, Experimental	3.8%
186	Mastocytosis	3.8%
187	Transfusion-Related Acute Lung Injury	3.8%
188	Bowen's Disease	3.8%
189	Paraganglioma	3.8%
190	Rhabdomyosarcoma	3.8%
191	Giant Cell Tumor of Bone	3.8%
192	Tuberous Sclerosis	3.8%
193	Abdominal Neoplasms	3.7%
194	Anemia	3.7%
195	Blood Coagulation Disorders	3.7%
196	Blood Platelet Disorders	3.7%
197	Bone Marrow Diseases	3.7%
198	Erythroplasia	3.7%
199	Follicular cyst	3.7%
200	Head and Neck Neoplasms	3.7%
201	Hemorrhagic Disorders	3.7%
202	Immune Complex Diseases	3.7%
203	Leukocyte Disorders	3.7%
204	Methemoglobinemia	3.7%
205	Mucocele	3.7%
206	Pancytopenia	3.7%
207	Pilonidal Cyst	3.7%
208	Polycythemia	3.7%
209	Soft Tissue Neoplasms	3.7%
210	Sulfhemoglobinemia	3.7%
211	Thoracic Neoplasms	3.7%
212	Thyroglossal Cyst	3.7%
213	Antiphospholipid Syndrome	3.7%
214	Synovial Cyst	3.7%
215	Thrombophilia	3.7%
216	Latex allergy	3.7%
217	Erythrocytosis	3.7%
218	Aberrant Crypt Foci	3.7%
219	Adenocarcinoma	3.6%
220	Carcinoma in Situ	3.6%
221	Carcinoma, Transitional Cell	3.6%
222	Phyllodes Tumor	3.6%
223	Dysgerminoma	3.6%
224	Hemangioendothelioma	3.6%
225	Lipoma	3.6%
226	Lymphohistiocytosis, Hemophagocytic	3.6%
227	Myoma	3.6%
228	Myxoma	3.6%
229	Neuroma	3.6%
230	Papilloma	3.6%
231	Pseudomyxoma Peritonei	3.6%
232	Seminoma	3.6%
233	Papillomatosis	3.6%
234	Angiolipoma	3.6%
235	Myelolipoma	3.6%
236	Neoplasms, Bone Tissue	3.6%
237	Neoplasms, Fibrous Tissue	3.6%
238	Smooth Muscle Tumor	3.6%
239	Adenomatosis, Pulmonary	3.6%
240	Adenomatous Polyps	3.6%
241	Carcinoma, Large Cell	3.6%
242	Carcinoma, Small Cell	3.6%
243	Desmoplastic Small Round Cell Tumor	3.6%
244	Schnitzler Syndrome	3.6%
245	Erdheim-Chester Disease	3.6%
246	Chondroma	3.6%
247	Enchondroma	3.6%
248	Malignant Carcinoid Syndrome	3.6%
249	Sarcoma 180	3.5%
250	Thrombocythemia, Essential	3.5%
251	Dermatofibrosarcoma	3.3%
252	Dermatofibrosarcoma Protuberans	3.3%
253	Neurofibrosarcoma	3.3%
254	Hemangioma, Cavernous	3.2%
255	Glioblastoma	3.2%
256	Neuroblastoma	3.2%
257	Glioblastoma Multiforme	3.2%
258	Basal Cell Nevus Syndrome	3.1%
259	Digestive System Neoplasms	3.1%
260	Endocrine Gland Neoplasms	3.1%
261	Eye Neoplasms	3.1%
262	Nervous System Neoplasms	3.1%
263	Environmental Illness	3.1%
264	Mesoblastic Nephroma	3%
265	Thrombasthenia	3%
266	Antithrombin III Deficiency	3%
267	Protein C Deficiency	3%
268	Bone neoplasms	3%
269	Leukoplakia	3%
270	Lupus Erythematosus, Systemic	3%
271	Pancreatic Cyst	3%
272	Pregnancy Complications, Hematologic	3%
273	Skin Neoplasms	3%
274	Overlap syndrome	3%
275	Addison Disease	3%
276	Barrett Esophagus	3%
277	Breast Cyst	3%
278	Actinic keratosis	3%
279	Mediastinal Cyst	3%
280	Neoplasm Invasiveness	3%
281	Neoplasm Metastasis	3%
282	Neoplasm Recurrence, Local	3%
283	Parovarian Cyst	3%
284	Pemphigus	3%
285	Pericardial Cyst	3%
286	Thymic Cyst	3%
287	Carcinogenesis	3%
288	Autoimmune thyroiditis	3%
289	Myxoid cyst	3%
290	Primary Adrenal Insufficiency	3%
291	Metastasis	3%
292	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.9%
293	Autoimmune hepatitis	2.9%
294	Mastocytosis, Systemic	2.9%
295	Pheochromocytoma	2.8%
296	Alveolar rhabdomyosarcoma	2.8%
297	Hepatocellular Adenoma	2.8%
298	Ganglioneuroblastoma	2.8%
299	Polycythemia Vera	2.7%
300	Wiskott-Aldrich Syndrome	2.7%
301	Vitamin K Deficiency	2.7%
302	Carcinoma, Pancreatic Ductal	2.7%
303	Multiple Endocrine Neoplasia Type 1	2.6%
304	Hydrops Fetalis	2.6%
305	Carcinoid Heart Disease	2.6%
306	Thrombocytosis	2.6%
307	Job Syndrome	2.6%
308	Kernicterus	2.6%
309	Afibrinogenemia	2.5%
310	Factor VII Deficiency	2.5%
311	Factor X Deficiency	2.5%
312	Factor XII Deficiency	2.5%
313	Hemophilia A	2.5%
314	Activated Protein C Resistance	2.5%
315	Factor II deficiency	2.5%
316	Factor VIII Deficiency	2.5%
317	Factor V deficiency	2.5%
318	Factor XI Deficiency	2.5%
319	Hypoprothrombinemias	2.5%
320	Acoustic Neuroma	2.5%
321	Latent Autoimmune Diabetes in Adults	2.5%
322	Dermatitis Herpetiformis	2.5%
323	Kounis Syndrome	2.5%
324	Liver Neoplasms, Experimental	2.5%
325	HIV Infections	2.5%
326	Sturge-Weber Syndrome	2.5%
327	Corpus Luteum Cyst	2.4%
328	Ovarian Cysts	2.4%
329	Eosinophilic Granuloma	2.4%
330	Splenosis	2.4%
331	Gastrointestinal Stromal Tumors	2.4%
332	Prolactinoma	2.4%
333	Growth Hormone-Secreting Pituitary Adenoma	2.4%
334	neurofibroma	2.4%
335	Hydatidiform Mole	2.4%
336	Adenoid Cystic Carcinoma	2.4%
337	fibroma	2.4%
338	Fibromatosis	2.4%
339	Osteoblastoma	2.4%
340	Osteoma	2.4%
341	Rhabdomyoma	2.4%
342	Chondromatosis	2.4%
343	Adenocarcinoma, Clear Cell	2.4%
344	Cholangiocarcinoma	2.4%
345	Cervical Intraepithelial Neoplasia	2.4%
346	Hemangioblastoma	2.4%
347	Lymphoma, Extranodal NK-T-Cell	2.4%
348	Lambert-Eaton Myasthenic Syndrome	2.4%
349	Parathyroid Neoplasms	2.4%
350	Peritoneal Neoplasms	2.4%
351	Thyroid Neoplasm	2.4%
352	Thyroid carcinoma	2.4%
353	Optic Nerve Glioma	2.3%
354	Adenomatous Polyposis Coli	2.2%
355	Chronic granulomatous disease	2.2%
356	Rheumatoid Arthritis	2.1%
357	Choledochal Cyst	2.1%
358	Juvenile arthritis	2.1%
359	granulosa cell tumor	2.1%
360	Carcinoma, Ovarian Epithelial	2.1%
361	Graves Disease	2.1%
362	Pancreatic Neoplasm	2.1%
363	Peutz-Jeghers Syndrome	2.1%
364	Anti-Glomerular Basement Membrane Disease	2.1%
365	Vipoma	2.1%
366	Asthma, Aspirin-Induced	2%
367	anaphylaxis	2%
368	Anemia, Hemolytic	2%
369	Anemia, Macrocytic	2%
370	Eosinophilia	2%
371	Food Allergy	2%
372	Hypoproteinemia	2%
373	Leukopenia	2%
374	Retroperitoneal Neoplasms	2%
375	Thrombocytopenia	2%
376	Leukostasis	2%
377	MYELODYSPLASTIC SYNDROME	2%
378	Anaphylactic shock	2%
379	Mastocytoma	1.9%
380	Hemoglobinuria, Paroxysmal	1.9%
381	Leukemoid Reaction	1.9%
382	Tracheal Neoplasms	1.9%
383	Leukoplakia, Oral	1.9%
384	Paraneoplastic Cerebellar Degeneration	1.8%
385	Serum Sickness	1.8%
386	Fibromatosis, Aggressive	1.8%
387	Fibromatosis, Abdominal	1.8%
388	Klatskin Tumor	1.8%
389	insulinoma	1.8%
390	Purpura, Thrombotic Thrombocytopenic	1.7%
391	Respiratory Hypersensitivity	1.7%
392	Nasopharyngeal carcinoma	1.7%
393	Denys-Drash Syndrome	1.6%
394	Anemia, Neonatal	1.6%
395	Leukocytosis	1.6%
396	Mouth Neoplasms	1.6%
397	Pelger-Huet Anomaly	1.6%
398	Sick Building Syndrome	1.6%
399	Central Nervous System Neoplasms	1.6%
400	Pleocytosis	1.6%
401	Multiple Chemical Sensitivity	1.6%
402	Vascular Neoplasms	1.6%
403	Esophageal Neoplasms	1.6%
404	Myelitis, Transverse	1.6%
405	Anemia, Sickle Cell	1.6%
406	Thalassemia	1.6%
407	Genital Neoplasms, Female	1.6%
408	Pancreatic Pseudocyst	1.6%
409	Urticaria	1.6%
410	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
411	Limbic Encephalitis	1.6%
412	HTLV-I Infections	1.6%
413	Lymphatic Metastasis	1.6%
414	Neoplasms, Unknown Primary	1.6%
415	Leukemic Infiltration	1.6%
416	Breast Neoplasms, Male	1.6%
417	Neoplasm Micrometastasis	1.6%
418	Triple Negative Breast Neoplasms	1.6%
419	Anemia, Diamond-Blackfan	1.6%
420	Adrenocortical carcinoma	1.6%
421	Leydig Cell Tumor	1.5%
422	Gastrinoma	1.5%
423	Glucagonoma	1.5%
424	Ataxia Telangiectasia	1.5%
425	Testicular Neoplasms	1.5%
426	Renal Cell Carcinoma	1.4%
427	Papillary Renal Cell Carcinoma	1.4%
428	Thyroid Nodule	1.4%
429	Adrenal Gland Neoplasms	1.4%
430	Gastrointestinal Neoplasms	1.4%
431	Genital Neoplasms, Male	1.4%
432	Liver neoplasms	1.4%
433	Uveal Neoplasms	1.4%
434	Myasthenia Gravis	1.4%
435	Urologic Neoplasms	1.4%
436	Uveomeningoencephalitic Syndrome	1.4%
437	Drug Eruptions	1.4%
438	Ecchymosis	1.4%
439	Petechiae	1.4%
440	Purpura	1.4%
441	Sebaceous Gland Neoplasms	1.4%
442	Spinal Neoplasms	1.4%
443	Xeroderma Pigmentosum	1.4%
444	Granulomatosis with polyangiitis	1.3%
445	Dermatitis, Allergic Contact	1.3%
446	HIV Seropositivity	1.3%
447	Polycystic Ovary Syndrome	1.3%
448	Carcinoma, Endometrioid	1.3%
449	Opsoclonus-Myoclonus Syndrome	1.3%
450	Dupuytren Contracture	1.2%
451	Purpura, Hyperglobulinemic	1.2%
452	Urticaria Pigmentosa	1.2%
453	Primary Myelofibrosis	1.2%
454	Agranulocytosis	1.2%
455	Anemia, Megaloblastic	1.2%
456	Lymphocytosis	1.2%
457	Myelofibrosis	1.2%
458	Myeloid Metaplasia	1.2%
459	Milk Allergy	1.2%
460	Hypoalbuminemia	1.2%
461	Wheat Hypersensitivity	1.2%
462	Hypereosinophilic syndrome	1.2%
463	bone marrow fibrosis	1.2%
464	Thrombotic Microangiopathies	1.2%
465	Stiff-Person Syndrome	1.2%
466	Polyradiculoneuropathy	1.2%
467	Polyradiculoneuritis	1.2%
468	Acquired Immunodeficiency Syndrome	1.2%
469	AIDS related complex	1.2%
470	Felty Syndrome	1.2%
471	Lupus Nephritis	1.1%
472	Hemolytic-Uremic Syndrome	1.1%
473	Myasthenia Gravis, Autoimmune, Experimental	1.1%
474	Waterhouse-Friderichsen Syndrome	1.1%
475	AIDS-Related Opportunistic Infections	1%
476	Vasculitis, Central Nervous System	1%
477	Sickle Cell Trait	1%
478	Dermatitis, Atopic	1%
479	ovarian neoplasm	1%
480	HIV Wasting Syndrome	1%
481	Rheumatoid Vasculitis	1%
482	AIDS Dementia Complex	1%
483	AIDS-Associated Nephropathy	1%
484	Nose Neoplasms	1%
485	Meningeal Neoplasms	1%
486	Pituitary Adenoma	0.9%
487	Pituitary Neoplasms	0.9%
488	Lupus Vasculitis, Central Nervous System	0.9%
489	Fanconi Anemia	0.9%
490	Sicca Syndrome	0.9%
491	Sjogren's Syndrome	0.9%
492	Palatal Neoplasms	0.9%
493	HIV-Associated Lipodystrophy Syndrome	0.9%
494	Ear Neoplasms	0.8%
495	Eyelid Neoplasms	0.8%
496	Lung Neoplasms	0.8%
497	Pleural Neoplasms	0.8%
498	Eosinophilia-Myalgia Syndrome	0.8%
499	Acute Chest Syndrome	0.8%
500	Zollinger-Ellison syndrome	0.8%
501	Angioedema	0.8%
502	Cell Transformation, Viral	0.8%
503	Brain Neoplasms	0.8%
504	Multiple Sclerosis	0.8%
505	Salivary Gland Neoplasms	0.8%
506	Shwartzman Phenomenon	0.8%
507	Spinal Cord Neoplasms	0.8%
508	Tongue Neoplasms	0.8%
509	Scurvy	0.8%
510	Uterine Neoplasms	0.8%
511	Vaginal Neoplasms	0.8%
512	Vulvar Neoplasms	0.8%
513	Purpura Fulminans	0.8%
514	Uterine Cancer	0.8%
515	Acute Generalized Exanthematous Pustulosis	0.8%
516	Fallopian Tube Neoplasms	0.8%
517	Neutropenia	0.8%
518	Atypical Hemolytic Uremic Syndrome	0.8%
519	Neuromyelitis Optica	0.7%
520	Leukoencephalitis, Acute Hemorrhagic	0.7%
521	Niemann-Pick Disease, Type C	0.7%
522	Pharyngeal Neoplasms	0.7%
523	Asthma	0.7%
524	Central Nervous System Cysts	0.7%
525	Bile Duct Neoplasms	0.7%
526	gallbladder neoplasm	0.7%
527	Intestinal Neoplasms	0.7%
528	Penile Neoplasms	0.7%
529	Prostatic Neoplasms	0.7%
530	Stomach Neoplasms	0.7%
531	Encephalomyelitis, Acute Disseminated	0.7%
532	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.7%
533	Erythema Nodosum	0.7%
534	Neuritis, Autoimmune, Experimental	0.7%
535	Dermatitis, Photoallergic	0.7%
536	Pulmonary Eosinophilia	0.6%
537	Eosinophilic Pneumonia	0.6%
538	Meningeal Carcinomatosis	0.6%
539	Anemia, Pernicious	0.6%
540	Laryngeal neoplasm	0.6%
541	Aspergillosis, Allergic Bronchopulmonary	0.6%
542	Guillain-Barre Syndrome	0.6%
543	Bladder Neoplasm	0.6%
544	Kidney Neoplasm	0.6%
545	Ureteral Neoplasms	0.6%
546	Urethral Neoplasms	0.6%
547	Febrile Neutropenia	0.6%
548	Bronchial Neoplasms	0.5%
549	Asthma, Exercise-Induced	0.5%
550	Status Asthmaticus	0.5%
551	Multiple Pulmonary Nodules	0.5%
552	Toxic Epidermal Necrolysis	0.5%
553	Stevens-Johnson Syndrome	0.5%
554	Supratentorial Neoplasms	0.5%
555	Multiple Sclerosis, Chronic Progressive	0.5%
556	Multiple Sclerosis, Relapsing-Remitting	0.5%
557	Endometrial Neoplasms	0.5%
558	Pseudoxanthoma Elasticum	0.5%
559	Giant Cell Arteritis	0.5%
560	Temporal Arteritis	0.5%
561	Asthma, Occupational	0.5%
562	Farmer's Lung	0.5%
563	Angioedemas, Hereditary	0.5%
564	Hypopharyngeal Neoplasms	0.5%
565	Pleural Effusion, Malignant	0.5%
566	Hypopharyngeal Cancer	0.5%
567	Hay fever	0.5%
568	Rhinitis, Allergic, Perennial	0.5%
569	Parotid Neoplasms	0.5%
570	Prostatic Neoplasms, Castration-Resistant	0.5%
571	Nelson Syndrome	0.5%
572	Cecal Neoplasms	0.4%
573	Duodenal Neoplasms	0.4%
574	Hereditary Angioedema Type III	0.4%
575	Hereditary Angioedema Types I and II	0.4%
576	Brain Stem Neoplasms	0.4%
577	Nasopharyngeal Neoplasms	0.4%
578	Colorectal Neoplasms	0.4%
579	Tonsillar Neoplasms	0.3%
580	Cerebellar Neoplasms	0.3%
581	Choroid Plexus Papilloma	0.3%
582	Paranasal Sinus Neoplasms	0.3%
583	Radicular Cyst	0.3%
584	Appendiceal Neoplasms	0.3%
585	Colonic Neoplasms	0.3%
586	Rectal Neoplasms	0.3%
587	Miller Fisher Syndrome	0.3%
588	Maxillary Sinus Neoplasms	0.2%
589	Anus Neoplasms	0.2%
590	Sigmoid Neoplasms	0.2%

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