MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Chloracne

(UMLS:C0263454)

Definition:: ACNE-like skin eruptions caused by exposure to CHLORINE-containing compounds. Exposure can be by inhalation, ingestion, or through the skin. Chloracne is often seen in people who have occupational contact with chlorinated pesticides, wood preservatives, and sealants.
UMLS ID:: C0263454
MeSH ID:: D054506

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.030.575

Synonym(s)

Chloracne

CHLORACNE

Chlorine acne

chloracne

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Leflunomide	FAERS: 1		US FAERS
2	3,4,3',4'-tetrachloroazobenzene		19737593	CTD
3	Polychlorinated Dibenzodioxins		View details 21410761 21998131 23152189 24161567	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Acne Vulgaris	44.4%
2	Acne	44.4%
3	Acne Conglobata	32.6%
4	Breast Diseases	31%
5	Dermatitis	31%
6	Exanthema	31%
7	Facial Dermatoses	31%
8	Hair Diseases	31%
9	Hand Dermatoses	31%
10	keratoacanthoma	31%
11	Keratosis	31%
12	Nail Diseases	31%
13	Photosensitivity Disorders	31%
14	Prurigo	31%
15	Pyoderma	31%
16	Rosacea	31%
17	Sebaceous Gland Diseases	31%
18	Skin Diseases, Vesiculobullous	31%
19	Skin Ulcer	31%
20	Sweat Gland Diseases	31%
21	Skin Diseases, Papulosquamous	31%
22	Skin Diseases, Vascular	31%
23	Ocular Rosacea	31%
24	Subcorneal pustular dermatosis	31%
25	Erythematotelangiectatic Rosacea	31%
26	Papulopustular Rosacea	31%
27	Chronic Actinic Dermatitis	31%
28	Pyoderma Gangrenosum	30%
29	Lupus Erythematosus, Cutaneous	27.9%
30	Panniculitis	27.9%
31	Systemic Scleroderma	27.9%
32	Morphea	27.9%
33	Contact Dermatitis	26.7%
34	Eczema	26.7%
35	Erythema Multiforme	26.7%
36	Intertrigo	26.7%
37	Neurodermatitis	26.7%
38	Rhinophyma	26.7%
39	Perioral Dermatitis	26.7%
40	Foot Ulcer	23.1%
41	Foot Diseases	22%
42	Dermatitis, Phototoxic	22%
43	Pityriasis Lichenoides et Varioliformis Acuta	22%
44	Pityriasis Lichenoides	22%
45	Phototoxicity	22%
46	Skin Abnormalities	20.9%
47	Skin Diseases, Infectious	20.9%
48	Skin Neoplasms	20.9%
49	Pigmentation Disorders	20.9%
50	Lipomatosis	20.5%
51	Pruritus	20.5%
52	Erythema	20.5%
53	Necrolytic Migratory Erythema	20.5%
54	Cutaneous Fistula	20.5%
55	Nephrogenic Fibrosing Dermopathy	20.5%
56	Nephrogenic Systemic Fibrosis	20.5%
57	Dermatitis Herpetiformis	20.3%
58	Acrodermatitis	20%
59	Anhidrosis	20%
60	Cholesteatoma	20%
61	Pressure Ulcer	20%
62	Dermatitis, Atopic	20%
63	Epidermolysis Bullosa	20%
64	Folliculitis	20%
65	Foot Dermatoses	20%
66	Gynecomastia	20%
67	Hypertrichosis	20%
68	Hypohidrosis	20%
69	Hypotrichosis	20%
70	Leg Ulcer	20%
71	Miliaria	20%
72	Parakeratosis	20%
73	Parapsoriasis	20%
74	Pityriasis	20%
75	Psoriasis	20%
76	Sebaceous Gland Neoplasms	20%
77	Sweet Syndrome	20%
78	Hidradenitis	20%
79	Onycholysis	20%
80	Miliaria Rubra	20%
81	Hyperpigmentation	20%
82	Porokeratosis	20%
83	Lichenoid Eruptions	20%
84	Gianotti-Crosti Syndrome	20%
85	Keratoderma, Palmoplantar	20%
86	Dermatitis, Irritant	19.6%
87	Connective Tissue Diseases	18.5%
88	Panniculitis, Lupus Erythematosus	18.4%
89	Xeroderma Pigmentosum	17.9%
90	Necrobiosis Lipoidica Diabeticorum	17.9%
91	Lupus Erythematosus, Discoid	17.8%
92	Scleroderma, Limited	17.8%
93	Dermatitis, Photoallergic	17.5%
94	Urticaria Pigmentosa	17.1%
95	Xeroderma	16.2%
96	Dermatomyositis	16.2%
97	Diaper Rash	16.1%
98	Dermatitis, Occupational	15.5%
99	Cutis Laxa	15.3%
100	Mastocytosis	15.1%
101	Lichen Planus	14.8%
102	Melanosis	14.8%
103	Chloasma	14.8%
104	Pityriasis Rosea	14.8%
105	Pityriasis Rubra Pilaris	14.8%
106	Vitiligo	14.8%
107	Dermatitis, Allergic Contact	14.8%
108	Lichen Nitidus	14.8%
109	Papillon-Lefevre Disease	14.6%
110	Erythema Induratum	14.4%
111	Erythema Infectiosum	14.1%
112	Exanthema Subitum	14%
113	Erythema Nodosum	13.7%
114	Acantholysis	13.6%
115	Breast Cyst	13.6%
116	Actinic keratosis	13.6%
117	Pemphigoid, Benign Mucous Membrane	13.6%
118	Pemphigus	13.6%
119	Piedra	13.6%
120	Sunburn	13.6%
121	Argyria	13.3%
122	Ectodermal Dysplasia	13.3%
123	Hirsutism	13.3%
124	Lactation Disorder	13.3%
125	Mastitis	13.3%
126	Urticaria	13.3%
127	Aplasia Cutis Congenita	13.3%
128	Adiposis Dolorosa	13.2%
129	Pruritus Vulvae	13.2%
130	Mastocytoma	13.1%
131	Pruritus Ani	13.1%
132	Tinea Capitis	12.7%
133	Onychomycosis	12.7%
134	Toxic Epidermal Necrolysis	12.6%
135	Stevens-Johnson Syndrome	12.6%
136	Pseudoxanthoma Elasticum	12.6%
137	Granuloma Annulare	12.4%
138	Acanthosis Nigricans	12.2%
139	Alopecia Areata	12.2%
140	Lentigo	12.2%
141	Ecthyma	11.5%
142	Hyperkeratosis, Epidermolytic	11%
143	Collagen Diseases	10.3%
144	Mixed Connective Tissue Disease	10.3%
145	Mucinoses	10.3%
146	Dermatomycoses	10.2%
147	Mucocutaneous Lymph Node Syndrome	10.2%
148	Skin Diseases, Bacterial	10.2%
149	Alopecia	10.1%
150	Sweating, Gustatory	10.1%
151	Androgenetic Alopecia	10.1%
152	Auriculotemporal Syndrome	10.1%
153	Drug Eruptions	10%
154	Lipodystrophy	10%
155	Livedo Reticularis	10%
156	Malignant Atrophic Papulosis	10%
157	Behcet Syndrome	10%
158	Lice Infestations	9.9%
159	Varicose Ulcer	9.9%
160	Breast Neoplasms, Male	9.9%
161	Triple Negative Breast Neoplasms	9.9%
162	Polyarteritis Nodosa	9.8%
163	Takayasu Arteritis	9.8%
164	Ichthyosis, X-Linked	9.8%
165	Hidradenitis Suppurativa	9.8%
166	Galactorrhea	9.8%
167	Sjogren-Larsson Syndrome	9.8%
168	Tinea Pedis	8.9%
169	Albinism	8.7%
170	Erythema Chronicum Migrans	8.5%
171	Lichen Planus, Oral	8.4%
172	Nail-Patella Syndrome	8.2%
173	Porphyrias, Hepatic	8.1%
174	Larva Migrans	7.6%
175	Leishmaniasis	7.6%
176	Molluscum Contagiosum	7.6%
177	Angioedema	7.5%
178	Onchocerciasis	7.5%
179	Chromoblastomycosis	7.4%
180	Dermatophytosis	7.4%
181	Sporotrichosis	7.4%
182	Tinea	7.4%
183	Tinea Versicolor	7.4%
184	Trichophytosis	7.4%
185	Hyalohyphomycosis	7.4%
186	Mycetoma	7.3%
187	Cartilage Diseases	7.3%
188	Rheumatism	7.3%
189	Chondromalacia	7.3%
190	Acute Generalized Exanthematous Pustulosis	7.3%
191	Lupus Erythematosus, Systemic	7%
192	Overlap syndrome	7%
193	Scleromyxedema	6.7%
194	Leishmaniasis, Cutaneous	6.1%
195	Eczema Herpeticum	6.1%
196	Warts	6.1%
197	Fusariosis	6%
198	Candidiasis, Chronic Mucocutaneous	5.9%
199	Cutaneous Candidiasis	5.9%
200	Erysipelas	5.9%
201	Serum Sickness	5.9%
202	Staphylococcal Skin Infections	5.9%
203	Variegate Porphyria	5.9%
204	Acute intermittent porphyria	5.9%
205	Porphyria Cutanea Tarda	5.9%
206	Erythrasma	5.9%
207	Carcinoma, Lobular	5.9%
208	Arthritis, Psoriatic	5.8%
209	CREST Syndrome	5.6%
210	Hereditary Angioedema Type III	5.4%
211	Hereditary Angioedema Types I and II	5.4%
212	Dupuytren Contracture	5%
213	Angioedemas, Hereditary	5%
214	Epidermodysplasia Verruciformis	4.9%
215	Herpes Labialis	4.9%
216	Giant Cell Arteritis	4.9%
217	Temporal Arteritis	4.9%
218	Diabetic Foot	4.9%
219	Staphylococcal Scalded Skin Syndrome	4.8%
220	Mesenteric Panniculitis	4.5%
221	Panniculitis, Peritoneal	4.5%
222	Tietze's Syndrome	4.5%
223	Orbital Cellulitis	4.5%
224	Myxoid cyst	4.5%
225	Peutz-Jeghers Syndrome	4.5%
226	Myxedema	4.4%
227	carbuncle	4.3%
228	Blastomycosis	4.2%
229	HIV-Associated Lipodystrophy Syndrome	4.2%
230	Condylomata Acuminata	4.1%
231	Furunculosis	4.1%
232	furuncle	4.1%
233	Cellulitis	4%
234	Impetigo	4%
235	Rhinoscleroma	3.8%
236	Menkes Kinky Hair Syndrome	3.5%
237	Osteochondritis	3.4%
238	Polymyalgia Rheumatica	3.4%
239	Osteogenesis Imperfecta	3.4%
240	Keloid	3.3%
241	Noonan Syndrome	2.9%
242	Rheumatoid Arthritis	2.7%
243	Juvenile arthritis	2.7%
244	Lupus Nephritis	2.6%
245	Marfan Syndrome	2.5%
246	Rheumatoid Nodule	2.5%
247	Homocystinuria	2.4%
248	Laryngomalacia	2.3%
249	Pectus carinatum	2.3%
250	Felty Syndrome	2%
251	Bronchomalacia	2%
252	Tracheomalacia	2%
253	Rheumatoid Vasculitis	1.6%
254	Mucopolysaccharidosis III	1.6%
255	Sicca Syndrome	1.4%
256	Sjogren's Syndrome	1.4%
257	Lupus Vasculitis, Central Nervous System	1.1%
258	Mucopolysaccharidosis II	1.1%

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