MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hodgkin Disease

(UMLS:C0019829)

Definition:: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
UMLS ID:: C0019829
MeSH ID:: D006689

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.386.355

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.515.569.355

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.683.515.761.355

Synonym(s)

Hodgkin Disease

Disease;Hodgkins

HD - Hodgkin's disease

HODGKIN'S DISEASE

HODGKINS DISEASE

HODGKINS DISEASE SYSTEMIC

Hodgkin

Hodgkin Lymphoma

10.

Hodgkin disease

11.

Hodgkin disease granuloma

12.

Hodgkin disease paragranuloma

13.

Hodgkin disease sarcoma

14.

Hodgkin granuloma

15.

Hodgkin granuloma [obs]

16.

Hodgkin lymphoma

Associated Drug(s)

	Name	Reference(s)	Data Source
1	ABVD protocol	View details 2427187 6206757 8675643 10332533 10798542 12162096 12586796 12805333 12907440 14565654 14657226 14752856 14760121 15183480 15199092 15315964 15453925 15465201 15621842 15837968 15941081 16135485 16172458 16264800 16314615 16640815 16736890 16794504 16879607 17065142 17071938 17085663 17168361 17420510 17459049 17515571 17562247 17562619 17606976 17646666 17673811 17713864 17726078 17846017 17954296 18024389 18072259 18154127 18180244 18209012 18310974 20026458 20399989	CTD
2	BEACOPP protocol	View details 12078889 12802024 16234521 16736890 17515571 19860621	CTD
3	Benzene	24552493	CTD
4	Bleomycin	View details 1329697 6459048 10526668 15147373 15922437 17290056 17606976 18293384 18501091	CTD
5	Busulfan	10955873	CTD
6	CEA protocol	17168361	CTD
7	CMOPP protocol	10798542	CTD
8	COPP protocol	View details 1297484 3665603 11426622 17713864 19418546	CTD
9	COPP-ABVD protocol	15064867 15925455	CTD
10	CVPP protocol	12805333 15453925	CTD
11	Carmustine	8477204	CTD
12	ChlVPP protocol	2332518 16314615	CTD
13	Cyclophosphamide	View details 1493456 3753658 4420129 5539280 8477204 10526668 16135485 17290056 17606976 17701600 18293384	CTD
14	Cytarabine	16200630 17304378	CTD
15	Dacarbazine	View details 509400 16170182 18293384 18501091	CTD
16	Dexa-BEAM protocol	17713864	CTD
17	Doxorubicin	View details 509400 1329697 6459048 8260898 11327539 15143078 15147373 15214719 15922437 17290056 17606976 18293384 18501091 19492170	CTD
18	EBVD protocol	View details 10721777 12952230 15170884 15183480 16966260 17726078	CTD
19	EBVP protocol	17515571	CTD
20	EPOCH protocol	8675643 11458812	CTD
21	EVAP protocol	14606767	CTD
22	Epirubicin	8260898 10526668 18180244	CTD
23	Etoposide	View details 8477204 10526668 15147373 16135485 16200630 17290056 17606976 18180244	CTD
24	Ifosfamide	6816479 16135485	CTD
25	Leucovorin	3465876	CTD
26	Lomustine	16135485	CTD
27	MOPP-ABV protocol	2411881 12586796	CTD
28	MOPPEBVCAD protocol	16172458	CTD
29	Mechlorethamine	View details 1329697 4688040 5013538 6089632	CTD
30	Melphalan	10955873	CTD
31	Methotrexate	3465876 17304378 17701600	CTD
32	Methylprednisolone	24158386	CTD
33	Mitoxantrone	8260898	CTD
34	OPP protocol	12805333	CTD
35	Phenytoin	7336147	CTD
36	Prednimustine	16135485	CTD
37	Prednisolone	10526668	CTD
38	Prednisone	View details 1329697 6089632 15922437 16135485 16794504 17290056 17606976 18293384	CTD
39	Procarbazine	View details 1329697 5013538 6089632 15922437 16135485 17606976 18293384	CTD
40	Stanford V protocol	10694546 16172458	CTD
41	Streptozocin	6459048	CTD
42	Teniposide	4609765	CTD
43	Tetrachloroethylene	24552493	CTD
44	Thiotepa	10955873	CTD
45	Uracil Mustard	10326707	CTD
46	VBA protocol	12805333 17515571	CTD
47	VBVP protocol	10735898	CTD
48	VMP protocol	16690523	CTD
49	Vinblastine	View details 509400 1329697 4163141 4301062 4336128 4688040 4821134 5013538 5768441 15922437 18180244 18501091	CTD
50	Vincristine	View details 934199 1329697 2531872 4007346 4348690 4352365 4916023 6089632 6092732 6459048 6896575 7313841 15147373 15922437 16135485 16794504 17290056 17606976 17701600 18293384 19770686	CTD
51	Vindesine	455587 7038420	CTD
52	afuresertib	25075128	CTD
53	aranoza	11826486	CTD
54	darinaparsin	25316819	CTD
55	gemcitabine	24158386	CTD
56	sodium arsenite	12676792	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Lymphoma, Non-Hodgkin	47.8%
2	Composite Lymphoma	46.7%
3	Sezary Syndrome	37%
4	Lymphoma, Follicular	35.5%
5	T-Cell Lymphoma	35.5%
6	Mantle cell lymphoma	35.5%
7	Lymphoma, T-Cell, Cutaneous	29.4%
8	Lymphoma, AIDS-Related	29.4%
9	Enteropathy-Associated T-Cell Lymphoma	29.4%
10	Primary Effusion Lymphoma	29.4%
11	Lymphomatoid Granulomatosis	28.4%
12	Tumor Lysis Syndrome	27.6%
13	Mycosis Fungoides	26.4%
14	Lymphomatoid Papulosis	26.4%
15	Plasmablastic lymphoma	26.4%
16	Autoimmune Lymphoproliferative Syndrome	22.6%
17	Burkitt Lymphoma	22.2%
18	Plasmacytoma	21.7%
19	Lymphangioleiomyomatosis	21.3%
20	Infectious Mononucleosis	21.1%
21	Leukemia, T-Cell	20%
22	Leukemia, B-Cell	20%
23	Primary amyloidosis	19.7%
24	Leukemia, Plasma Cell	19%
25	Histiocytic Disorders, Malignant	18%
26	Heavy Chain Disease	17.5%
27	Sarcoidosis	17.2%
28	Waldenstrom Macroglobulinemia	16.8%
29	Multiple Myeloma	16.8%
30	Neoplasms, Neuroepithelial	16.3%
31	Gliomatosis cerebri	16.3%
32	Agammaglobulinemia	16.1%
33	Neuroectodermal Tumors	15.8%
34	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	15.3%
35	Leukemia, Large Granular Lymphocytic	15.3%
36	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	15.3%
37	leukemia	15%
38	Neoplasms, Germ Cell and Embryonal	15%
39	Neoplasms, Glandular and Epithelial	15%
40	Germ Cell Cancer	15%
41	Medulloblastoma	14.9%
42	melanoma	14.6%
43	Lymphocele	14.2%
44	Lymphoma, Extranodal NK-T-Cell	14.2%
45	Granuloma	14%
46	Carcinosarcoma	13.7%
47	Hemangiosarcoma	13.7%
48	lymphangiosarcoma	13.7%
49	Thymoma	13.1%
50	Adenoma, Acidophil	12.9%
51	Ganglioneuroma	12.9%
52	Glioma	12.9%
53	Malignant Glioma	12.9%
54	Thymus Neoplasms	12.7%
55	Adenitis	12.5%
56	Histiocytosis	12.5%
57	Lymphadenitis	12.5%
58	Lymphangitis	12.5%
59	Lymphedema	12.5%
60	Splenic Diseases	12.5%
61	Thymus Hyperplasia	12.5%
62	Pseudolymphoma	12.5%
63	Lymphadenopathy	12.5%
64	Meningioma	12.4%
65	Carcinoma 256, Walker	12.3%
66	Carcinoid Tumor	12.1%
67	Neurilemmoma	12.1%
68	Hutchinson's Melanotic Freckle	12.1%
69	Melanoma, Amelanotic	12.1%
70	Paraproteinemias	12%
71	Malignant histiocytosis	11.8%
72	Histiocytic sarcoma	11.8%
73	Basal cell carcinoma	11.7%
74	Carcinoma, Papillary	11.7%
75	Squamous cell carcinoma	11.7%
76	Chondrosarcoma	11.7%
77	Craniopharyngioma	11.7%
78	Cystadenoma	11.7%
79	leiomyosarcoma	11.7%
80	liposarcoma	11.7%
81	Mesothelioma	11.7%
82	synovial sarcoma	11.7%
83	Neuroectodermal Tumor, Melanotic	11.7%
84	Angiomyolipoma	11.7%
85	Clear Cell Sarcoma of Soft Tissue	11.7%
86	Alveolar Soft Part Sarcoma	11.7%
87	Neuroendocrine Tumors	11.7%
88	Sarcoma, Myeloid	11.7%
89	Carcinoma, Basal Cell	11.7%
90	Melanoma, Experimental	11.6%
91	Astrocytoma	11.2%
92	Ependymoma	11.2%
93	oligodendroglioma	11.2%
94	Ganglioglioma	11.2%
95	gliosarcoma	11.2%
96	Anaplastic astrocytoma	11.2%
97	Anaplastic Oligodendroglioma	11.2%
98	Malignant Carcinoid Syndrome	10.8%
99	Cystadenocarcinoma	10.7%
100	Fibrosarcoma	10.7%
101	Osteosarcoma	10.7%
102	Mucoepidermoid Carcinoma	10.7%
103	Glioblastoma	10.4%
104	Neuroblastoma	10.4%
105	Glioblastoma Multiforme	10.4%
106	Monoclonal Gammopathy of Undetermined Significance	10.3%
107	Adenofibroma	10.2%
108	Fibroadenoma	10.2%
109	Malignant Fibrous Histiocytoma	10.2%
110	Lymphatic Abnormalities	10.1%
111	Hypergammaglobulinemia	10.1%
112	Splenic Neoplasms	10%
113	Trophoblastic Neoplasms	10%
114	Ganglioneuroblastoma	10%
115	Leukemia, Experimental	9.9%
116	Carcinoma, Ehrlich Tumor	9.9%
117	Dermoid Cyst	9.9%
118	Carcinoma, Lewis Lung	9.9%
119	Lymphangiectasis, Intestinal	9.9%
120	Adenoma	9.8%
121	Ameloblastoma	9.8%
122	Angiokeratoma	9.8%
123	Carcinoma	9.8%
124	Chordoma	9.8%
125	Hemangioma	9.8%
126	hemangiopericytoma	9.8%
127	Lymphangioma	9.8%
128	Mesenchymoma	9.8%
129	Nevus	9.8%
130	Teratoma	9.8%
131	Hepatoblastoma	9.8%
132	Mixed Tumor, Mullerian	9.8%
133	Germinoma	9.8%
134	Teratocarcinoma	9.8%
135	Angiofibroma	9.8%
136	Sarcoma	9.8%
137	Epithelioma	9.8%
138	Transfusion Reaction	9.7%
139	Hypotensive Transfusion Reaction	9.7%
140	Bowen's Disease	9.7%
141	Paraganglioma	9.7%
142	Rhabdomyosarcoma	9.7%
143	Giant Cell Tumor of Bone	9.7%
144	Choriocarcinoma	9.5%
145	Carcinoma, Lobular	9.5%
146	Dermatofibrosarcoma	9.2%
147	Dermatofibrosarcoma Protuberans	9.2%
148	Sarcoidosis, Pulmonary	9.2%
149	Endometrial Stromal Sarcoma	9%
150	Carcinoid Heart Disease	8.9%
151	Retinoblastoma	8.9%
152	Neurofibrosarcoma	8.7%
153	Pheochromocytoma	8.7%
154	Alveolar rhabdomyosarcoma	8.7%
155	Hamartoma	8.6%
156	Neoplasms, Hormone-Dependent	8.6%
157	Neoplasms, Multiple Primary	8.6%
158	Paraneoplastic Syndromes	8.6%
159	Precancerous Conditions	8.6%
160	Neoplasms, Second Primary	8.6%
161	Leukemia, Radiation-Induced	8.6%
162	Leukemia L1210	8.5%
163	Leukemia P388	8.5%
164	Acanthoma	8.5%
165	Mucocutaneous Lymph Node Syndrome	8.3%
166	Sarcoma, Experimental	8.2%
167	Autoimmune Diseases	7.8%
168	Hypersensitivity	7.8%
169	Immunologic Deficiency Syndromes	7.8%
170	Immune reconstitution syndrome	7.8%
171	Immune Reconstitution Inflammatory Syndrome	7.8%
172	Sarcoma 180	7.5%
173	Hematologic Neoplasms	7.4%
174	Elephantiasis	7.4%
175	Hypersplenism	7.4%
176	Elephantiasis Nostras Verrucosa	7.4%
177	Adenocarcinoma	7.3%
178	Carcinoma in Situ	7.3%
179	Carcinoma, Transitional Cell	7.3%
180	Phyllodes Tumor	7.3%
181	Dysgerminoma	7.3%
182	Hemangioendothelioma	7.3%
183	Lipoma	7.3%
184	Myoma	7.3%
185	Myxoma	7.3%
186	Neuroma	7.3%
187	Papilloma	7.3%
188	Pseudomyxoma Peritonei	7.3%
189	Seminoma	7.3%
190	Papillomatosis	7.3%
191	Angiolipoma	7.3%
192	Myelolipoma	7.3%
193	Neoplasms, Bone Tissue	7.3%
194	Neoplasms, Fibrous Tissue	7.3%
195	Smooth Muscle Tumor	7.3%
196	Adenomatosis, Pulmonary	7.3%
197	Adenomatous Polyps	7.3%
198	Carcinoma, Large Cell	7.3%
199	Carcinoma, Small Cell	7.3%
200	Desmoplastic Small Round Cell Tumor	7.3%
201	Chondroma	7.3%
202	Enchondroma	7.3%
203	Leukemia, Myelomonocytic, Chronic	7.1%
204	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	7.1%
205	Acoustic Neuroma	7%
206	Cyst	6.9%
207	Neoplastic Processes	6.9%
208	Neoplastic Syndromes, Hereditary	6.9%
209	Pregnancy Complications, Neoplastic	6.9%
210	Neoplasms, Experimental	6.8%
211	Multiple Endocrine Neoplasia	6.8%
212	Mastocytosis	6.6%
213	Carcinoma, Pancreatic Ductal	6.6%
214	Basal Cell Nevus Syndrome	6.4%
215	Optic Nerve Glioma	6.4%
216	Mastocytosis, Systemic	6.1%
217	Nephroblastoma	6.1%
218	Cryoglobulinemia	6.1%
219	Adenoid Cystic Carcinoma	6.1%
220	fibroma	6.1%
221	Fibromatosis	6.1%
222	Osteoblastoma	6.1%
223	Osteoma	6.1%
224	Rhabdomyoma	6.1%
225	Chondromatosis	6.1%
226	Adenocarcinoma, Clear Cell	6.1%
227	Cholangiocarcinoma	6.1%
228	Cervical Intraepithelial Neoplasia	6.1%
229	Hemangioblastoma	6.1%
230	Splenic Infarction	6%
231	Hemangioma, Cavernous	6%
232	Vipoma	5.9%
233	Histiocytosis, Langerhans-Cell	5.9%
234	Leukemia, Myeloid, Chronic-Phase	5.8%
235	Neoplasms, Radiation-Induced	5.7%
236	Hydatidiform Mole	5.6%
237	Paraneoplastic Encephalomyelitis	5.6%
238	Hepatocellular Adenoma	5.6%
239	Mammary Neoplasms, Experimental	5.5%
240	Bone Marrow Neoplasms	5.5%
241	Fibromatosis, Aggressive	5.5%
242	Fibromatosis, Abdominal	5.5%
243	Klatskin Tumor	5.5%
244	Mesoblastic Nephroma	5.2%
245	Thrombocytopenic purpura	5.2%
246	Autoimmune thrombocytopenia	5.2%
247	Immune thrombocytopenic purpura	5.2%
248	POEMS Syndrome	5.1%
249	Splenic Rupture	5.1%
250	Tuberous Sclerosis	5%
251	Glomerulonephritis, Membranoproliferative	5%
252	Abdominal Neoplasms	5%
253	Erythroplasia	5%
254	Follicular cyst	5%
255	Head and Neck Neoplasms	5%
256	Mucocele	5%
257	Pilonidal Cyst	5%
258	Soft Tissue Neoplasms	5%
259	Thoracic Neoplasms	5%
260	Thyroglossal Cyst	5%
261	Synovial Cyst	5%
262	Aberrant Crypt Foci	5%
263	Sturge-Weber Syndrome	5%
264	Disseminated Intravascular Coagulation	4.9%
265	Protein S Deficiency	4.9%
266	Gastrointestinal Stromal Tumors	4.9%
267	Mastocytoma	4.9%
268	Prolactinoma	4.9%
269	Growth Hormone-Secreting Pituitary Adenoma	4.9%
270	Lymphohistiocytosis, Hemophagocytic	4.9%
271	Schnitzler Syndrome	4.9%
272	Erdheim-Chester Disease	4.9%
273	neurofibroma	4.9%
274	Lymphopenia	4.6%
275	Multiple Endocrine Neoplasia Type 1	4.5%
276	insulinoma	4.5%
277	Thrombocythemia, Essential	4.4%
278	Transfusion-Related Acute Lung Injury	4.4%
279	granulosa cell tumor	4.3%
280	Carcinoma, Ovarian Epithelial	4.3%
281	Adenomatous Polyposis Coli	4.3%
282	Gastrinoma	4.2%
283	Glucagonoma	4.2%
284	Anemia	4.2%
285	Blood Coagulation Disorders	4.2%
286	Blood Platelet Disorders	4.2%
287	Bone Marrow Diseases	4.2%
288	Digestive System Neoplasms	4.2%
289	Endocrine Gland Neoplasms	4.2%
290	Eye Neoplasms	4.2%
291	Hemorrhagic Disorders	4.2%
292	Immune Complex Diseases	4.2%
293	Leukocyte Disorders	4.2%
294	Methemoglobinemia	4.2%
295	Nervous System Neoplasms	4.2%
296	Pancytopenia	4.2%
297	Polycythemia	4.2%
298	Polycythemia Vera	4.2%
299	Sulfhemoglobinemia	4.2%
300	Antiphospholipid Syndrome	4.2%
301	Thrombophilia	4.2%
302	Latex allergy	4.2%
303	Erythrocytosis	4.2%
304	Bone neoplasms	4.1%
305	Leukoplakia	4.1%
306	Pancreatic Cyst	4.1%
307	Skin Neoplasms	4.1%
308	Adrenocortical carcinoma	4%
309	Barrett Esophagus	4%
310	Breast Cyst	4%
311	Actinic keratosis	4%
312	Mediastinal Cyst	4%
313	Neoplasm Invasiveness	4%
314	Neoplasm Metastasis	4%
315	Neoplasm Recurrence, Local	4%
316	Parovarian Cyst	4%
317	Pericardial Cyst	4%
318	Thymic Cyst	4%
319	Carcinogenesis	4%
320	Myxoid cyst	4%
321	Metastasis	4%
322	Leydig Cell Tumor	3.9%
323	Parathyroid Neoplasms	3.8%
324	Peritoneal Neoplasms	3.8%
325	Thyroid Neoplasm	3.8%
326	Thyroid carcinoma	3.8%
327	Thrombasthenia	3.8%
328	Antithrombin III Deficiency	3.8%
329	Protein C Deficiency	3.8%
330	Liver Neoplasms, Experimental	3.7%
331	Dupuytren Contracture	3.7%
332	Lambert-Eaton Myasthenic Syndrome	3.7%
333	Urticaria Pigmentosa	3.7%
334	Nasopharyngeal carcinoma	3.6%
335	Renal Cell Carcinoma	3.6%
336	Papillary Renal Cell Carcinoma	3.6%
337	Environmental Illness	3.5%
338	Carcinoma, Endometrioid	3.5%
339	Wiskott-Aldrich Syndrome	3.5%
340	Pancreatic Neoplasm	3.4%
341	Lupus Erythematosus, Systemic	3.4%
342	Pregnancy Complications, Hematologic	3.4%
343	Overlap syndrome	3.4%
344	Tracheal Neoplasms	3.3%
345	Addison Disease	3.3%
346	Pemphigus	3.3%
347	Autoimmune thyroiditis	3.3%
348	Primary Adrenal Insufficiency	3.3%
349	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.3%
350	Autoimmune hepatitis	3.3%
351	Corpus Luteum Cyst	3.3%
352	Ovarian Cysts	3.3%
353	Eosinophilic Granuloma	3.3%
354	Leukoplakia, Oral	3.3%
355	Retroperitoneal Neoplasms	3.3%
356	Splenosis	3.3%
357	Afibrinogenemia	3.3%
358	Factor VII Deficiency	3.3%
359	Factor X Deficiency	3.3%
360	Factor XII Deficiency	3.3%
361	Hemophilia A	3.3%
362	Paraneoplastic Cerebellar Degeneration	3.3%
363	Activated Protein C Resistance	3.3%
364	Factor II deficiency	3.3%
365	Factor VIII Deficiency	3.3%
366	Factor V deficiency	3.3%
367	Factor XI Deficiency	3.3%
368	Hypoprothrombinemias	3.3%
369	Vitamin K Deficiency	3.3%
370	Thrombocytosis	3.3%
371	Job Syndrome	3.3%
372	Denys-Drash Syndrome	3.3%
373	Hydrops Fetalis	3.1%
374	Kernicterus	3%
375	Choledochal Cyst	2.9%
376	Esophageal Neoplasms	2.9%
377	Limbic Encephalitis	2.9%
378	Peutz-Jeghers Syndrome	2.8%
379	Thyroid Nodule	2.8%
380	Latent Autoimmune Diabetes in Adults	2.8%
381	Dermatitis Herpetiformis	2.8%
382	Kounis Syndrome	2.8%
383	HIV Infections	2.8%
384	Chronic granulomatous disease	2.7%
385	Myelitis, Transverse	2.7%
386	Mouth Neoplasms	2.7%
387	Central Nervous System Neoplasms	2.7%
388	Vascular Neoplasms	2.7%
389	Genital Neoplasms, Female	2.6%
390	Pancreatic Pseudocyst	2.6%
391	Lymphatic Metastasis	2.6%
392	Neoplasms, Unknown Primary	2.6%
393	Leukemic Infiltration	2.6%
394	Breast Neoplasms, Male	2.6%
395	Neoplasm Micrometastasis	2.6%
396	Triple Negative Breast Neoplasms	2.6%
397	Hemoglobinuria, Paroxysmal	2.6%
398	Leukemoid Reaction	2.6%
399	Testicular Neoplasms	2.6%
400	Asthma, Aspirin-Induced	2.5%
401	anaphylaxis	2.5%
402	Anemia, Hemolytic	2.5%
403	Anemia, Macrocytic	2.5%
404	Eosinophilia	2.5%
405	Food Allergy	2.5%
406	Hypoproteinemia	2.5%
407	Leukopenia	2.5%
408	Thrombocytopenia	2.5%
409	Leukostasis	2.5%
410	MYELODYSPLASTIC SYNDROME	2.5%
411	Anaphylactic shock	2.5%
412	Rheumatoid Arthritis	2.4%
413	Juvenile arthritis	2.4%
414	Graves Disease	2.4%
415	Anti-Glomerular Basement Membrane Disease	2.3%
416	Serum Sickness	2.3%
417	Opsoclonus-Myoclonus Syndrome	2.3%
418	Purpura, Thrombotic Thrombocytopenic	2.3%
419	Anemia, Diamond-Blackfan	2.3%
420	Adrenal Gland Neoplasms	2.2%
421	Gastrointestinal Neoplasms	2.2%
422	Genital Neoplasms, Male	2.2%
423	Liver neoplasms	2.2%
424	Uveal Neoplasms	2.2%
425	Urologic Neoplasms	2.2%
426	Sebaceous Gland Neoplasms	2.2%
427	Spinal Neoplasms	2.2%
428	Polycystic Ovary Syndrome	2.2%
429	Anemia, Sickle Cell	2.1%
430	Thalassemia	2.1%
431	Respiratory Hypersensitivity	2.1%
432	Nose Neoplasms	2%
433	Anemia, Neonatal	2%
434	Leukocytosis	2%
435	Pelger-Huet Anomaly	2%
436	Sick Building Syndrome	2%
437	Pleocytosis	2%
438	Multiple Chemical Sensitivity	2%
439	Palatal Neoplasms	2%
440	Urticaria	2%
441	Vasculitis, Leukocytoclastic, Cutaneous	2%
442	HTLV-I Infections	2%
443	Meningeal Neoplasms	2%
444	Pituitary Adenoma	1.8%
445	Pituitary Neoplasms	1.8%
446	Xeroderma Pigmentosum	1.8%
447	Ear Neoplasms	1.7%
448	Eyelid Neoplasms	1.7%
449	Lung Neoplasms	1.7%
450	Pleural Neoplasms	1.7%
451	Ataxia Telangiectasia	1.7%
452	Myasthenia Gravis	1.7%
453	Uveomeningoencephalitic Syndrome	1.7%
454	ovarian neoplasm	1.6%
455	Drug Eruptions	1.6%
456	Ecchymosis	1.6%
457	Petechiae	1.6%
458	Purpura	1.6%
459	Cell Transformation, Viral	1.6%
460	Brain Neoplasms	1.6%
461	Salivary Gland Neoplasms	1.6%
462	Spinal Cord Neoplasms	1.6%
463	Tongue Neoplasms	1.6%
464	Granulomatosis with polyangiitis	1.6%
465	Dermatitis, Allergic Contact	1.6%
466	Primary Myelofibrosis	1.6%
467	Agranulocytosis	1.6%
468	Anemia, Megaloblastic	1.6%
469	HIV Seropositivity	1.6%
470	Lymphocytosis	1.6%
471	Myelofibrosis	1.6%
472	Myeloid Metaplasia	1.6%
473	Purpura, Hyperglobulinemic	1.6%
474	Milk Allergy	1.6%
475	Hypoalbuminemia	1.6%
476	Wheat Hypersensitivity	1.6%
477	Hypereosinophilic syndrome	1.6%
478	bone marrow fibrosis	1.6%
479	Thrombotic Microangiopathies	1.6%
480	Uterine Neoplasms	1.6%
481	Vaginal Neoplasms	1.6%
482	Vulvar Neoplasms	1.6%
483	Uterine Cancer	1.6%
484	Meningeal Carcinomatosis	1.6%
485	Fallopian Tube Neoplasms	1.6%
486	Hemolytic-Uremic Syndrome	1.6%
487	Sickle Cell Trait	1.5%
488	Pharyngeal Neoplasms	1.4%
489	Myasthenia Gravis, Autoimmune, Experimental	1.4%
490	Stiff-Person Syndrome	1.4%
491	Polyradiculoneuropathy	1.4%
492	Polyradiculoneuritis	1.4%
493	Central Nervous System Cysts	1.4%
494	Acquired Immunodeficiency Syndrome	1.4%
495	AIDS related complex	1.4%
496	Bile Duct Neoplasms	1.4%
497	gallbladder neoplasm	1.4%
498	Intestinal Neoplasms	1.4%
499	Penile Neoplasms	1.4%
500	Prostatic Neoplasms	1.4%
501	Stomach Neoplasms	1.4%
502	Felty Syndrome	1.4%
503	Fanconi Anemia	1.4%
504	Lupus Nephritis	1.4%
505	Bronchial Neoplasms	1.4%
506	Multiple Pulmonary Nodules	1.4%
507	Supratentorial Neoplasms	1.3%
508	Waterhouse-Friderichsen Syndrome	1.3%
509	Endometrial Neoplasms	1.3%
510	Zollinger-Ellison syndrome	1.3%
511	Laryngeal neoplasm	1.3%
512	Atypical Hemolytic Uremic Syndrome	1.3%
513	AIDS-Related Opportunistic Infections	1.3%
514	Vasculitis, Central Nervous System	1.2%
515	Dermatitis, Atopic	1.2%
516	HIV Wasting Syndrome	1.2%
517	Bladder Neoplasm	1.2%
518	Kidney Neoplasm	1.2%
519	Ureteral Neoplasms	1.2%
520	Urethral Neoplasms	1.2%
521	Rheumatoid Vasculitis	1.2%
522	AIDS Dementia Complex	1.2%
523	AIDS-Associated Nephropathy	1.2%
524	Neutropenia	1.2%
525	Brain Stem Neoplasms	1.2%
526	Acute Chest Syndrome	1.2%
527	Hypopharyngeal Neoplasms	1.2%
528	Pleural Effusion, Malignant	1.2%
529	Hypopharyngeal Cancer	1.2%
530	Lupus Vasculitis, Central Nervous System	1.2%
531	Parotid Neoplasms	1.2%
532	Prostatic Neoplasms, Castration-Resistant	1.2%
533	Nelson Syndrome	1.2%
534	Choroid Plexus Papilloma	1.1%
535	Eosinophilia-Myalgia Syndrome	1.1%
536	Angioedema	1.1%
537	Niemann-Pick Disease, Type C	1.1%
538	Multiple Sclerosis	1.1%
539	Shwartzman Phenomenon	1.1%
540	Sicca Syndrome	1.1%
541	Sjogren's Syndrome	1.1%
542	Scurvy	1.1%
543	Purpura Fulminans	1.1%
544	Acute Generalized Exanthematous Pustulosis	1.1%
545	HIV-Associated Lipodystrophy Syndrome	1.1%
546	Tonsillar Neoplasms	1%
547	Neuromyelitis Optica	1%
548	Cerebellar Neoplasms	1%
549	Leukoencephalitis, Acute Hemorrhagic	1%
550	Cecal Neoplasms	1%
551	Duodenal Neoplasms	1%
552	Febrile Neutropenia	1%
553	Pulmonary Eosinophilia	1%
554	Eosinophilic Pneumonia	1%
555	Anemia, Pernicious	1%
556	Asthma	1%
557	Encephalomyelitis, Acute Disseminated	0.9%
558	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.9%
559	Erythema Nodosum	0.9%
560	Neuritis, Autoimmune, Experimental	0.9%
561	Dermatitis, Photoallergic	0.9%
562	Nasopharyngeal Neoplasms	0.9%
563	Radicular Cyst	0.9%
564	Appendiceal Neoplasms	0.9%
565	Colonic Neoplasms	0.9%
566	Rectal Neoplasms	0.9%
567	Colorectal Neoplasms	0.9%
568	Paranasal Sinus Neoplasms	0.8%
569	Aspergillosis, Allergic Bronchopulmonary	0.8%
570	Guillain-Barre Syndrome	0.8%
571	Asthma, Exercise-Induced	0.8%
572	Status Asthmaticus	0.8%
573	Multiple Sclerosis, Chronic Progressive	0.8%
574	Multiple Sclerosis, Relapsing-Remitting	0.8%
575	Anus Neoplasms	0.8%
576	Sigmoid Neoplasms	0.8%
577	Maxillary Sinus Neoplasms	0.7%
578	Asthma, Occupational	0.7%
579	Toxic Epidermal Necrolysis	0.7%
580	Stevens-Johnson Syndrome	0.7%
581	Farmer's Lung	0.7%
582	Angioedemas, Hereditary	0.7%
583	Hay fever	0.7%
584	Rhinitis, Allergic, Perennial	0.7%
585	Hereditary Angioedema Type III	0.7%
586	Hereditary Angioedema Types I and II	0.7%
587	Pseudoxanthoma Elasticum	0.7%
588	Giant Cell Arteritis	0.7%
589	Temporal Arteritis	0.7%
590	Miller Fisher Syndrome	0.4%

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