MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ventricular Flutter

(UMLS:C0152173)

Definition:: A potentially lethal cardiac arrhythmia characterized by an extremely rapid, hemodynamically unstable ventricular tachycardia (150-300 beats/min) with a large oscillating sine-wave appearance. If untreated, ventricular flutter typically progresses to VENTRICULAR FIBRILLATION.
UMLS ID:: C0152173
MeSH ID:: D054141

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.067.961

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.073.961

Synonym(s)

Ventricular Flutter

Flutter, Ventricular

Flutter;ventricular

Ventricular flutter

flutter; ventricular

ventricular flutter

ventricular; flutter

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Insulin	FAERS: 3		US FAERS
2	Oseltamivir	FAERS: 3		US FAERS
3	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 2		US FAERS
4	Carbamazepine	FAERS: 2		US FAERS
5	sofosbuvir-velpatasvir drug combination	FAERS: 2		US FAERS
6	4-hydroxybutyric acid	FAERS: 1		US FAERS
7	Amiodarone	FAERS: 1	7398728	CTD US FAERS
8	Azacitidine	FAERS: 1		US FAERS
9	Capecitabine	FAERS: 1		US FAERS
10	Dabigatran	FAERS: 1		US FAERS
11	Indapamide	FAERS: 1		US FAERS
12	Lenalidomide	FAERS: 1		US FAERS
13	Mefenamic Acid	FAERS: 1		US FAERS
14	Moxifloxacin	FAERS: 1		US FAERS
15	Ranolazine	FAERS: 1		US FAERS
16	Risperidone	FAERS: 1		US FAERS
17	Ropivacaine	FAERS: 1		US FAERS
18	Rosiglitazone	FAERS: 1		US FAERS
19	Sertraline	FAERS: 1		US FAERS
20	Tacrolimus	FAERS: 1		US FAERS
21	Teriparatide	FAERS: 1		US FAERS
22	rofecoxib	FAERS: 1		US FAERS
23	Atropine			SIDER
24	Cytarabine			OFFSIDES
25	Disopyramide		250503 7445656 9752618	CTD
26	Donepezil			OFFSIDES
27	Etoposide			OFFSIDES
28	Gatifloxacin			OFFSIDES
29	Mexiletine			OFFSIDES
30	Mitoxantrone			OFFSIDES
31	Oseltamivir			OFFSIDES
32	Pemetrexed			OFFSIDES
33	Phenprocoumon			OFFSIDES
34	Quinidine		970334 1562122 7445656	CTD
35	Salmeterol Xinafoate			OFFSIDES
36	Thioridazine		7177942	CTD
37	alfacalcidol			OFFSIDES
38	gemcitabine		10541971	CTD
39	voglibose			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Sinus Arrhythmia	46.7%
2	Atrial Fibrillation	46.7%
3	Atrial Flutter	46.7%
4	Ventricular Fibrillation	46.7%
5	Parasystole	46.7%
6	Paroxysmal atrial fibrillation	46.7%
7	Bradycardia	46.7%
8	Heart Block	45.3%
9	Tachycardia	45.3%
10	Tachyarrhythmia	45.3%
11	Sick Sinus Syndrome	43.3%
12	Long QT Syndrome	37.6%
13	Sinus Arrest, Cardiac	34.4%
14	Adams-Stokes Syndrome	33.3%
15	Atrioventricular Block	33.3%
16	Bundle-Branch Block	33.3%
17	Atrial Premature Complexes	33.3%
18	Sinoatrial Block	33.3%
19	Tachycardia, Paroxysmal	33.3%
20	Supraventricular tachycardia	33.3%
21	Tachycardia, Ventricular	33.3%
22	Tachycardia, Reciprocating	33.3%
23	Romano-Ward Syndrome	27.6%
24	Tachycardia, Atrioventricular Nodal Reentry	27.5%
25	Tachycardia, Ectopic Atrial	27.5%
26	Tachycardia, Ectopic Junctional	27.5%
27	Sinus Tachycardia	27.5%
28	Torsades de Pointes	27.5%
29	Accelerated Idioventricular Rhythm	27.5%
30	Postpericardiotomy Syndrome	25.4%
31	Lown-Ganong-Levine Syndrome	24.6%
32	Cardiac Output, High	20.7%
33	Polydipsia	20.7%
34	Myocardial Ischemia	20.7%
35	Myocardial Stunning	20.7%
36	Low Cardiac Output Syndrome	20.7%
37	Ascites	20.5%
38	Cardiac Tamponade	20.5%
39	Endocarditis	20.5%
40	Fibrosis	20.5%
41	Gliosis	20.5%
42	Growth Disorders	20.5%
43	Cardiac Arrest	20.5%
44	Heart failure	20.5%
45	Hemorrhage	20.5%
46	Hyperbilirubinemia	20.5%
47	Hyperplasia	20.5%
48	Hypomenorrhea	20.5%
49	Inflammation	20.5%
50	Intraoperative Complications	20.5%
51	Ischemia	20.5%
52	Lithiasis	20.5%
53	Malacoplakia	20.5%
54	Menstruation Disturbances	20.5%
55	Metaplasia	20.5%
56	Nerve Degeneration	20.5%
57	Ochronosis	20.5%
58	Pericardial effusion	20.5%
59	Pericarditis	20.5%
60	Pneumopericardium	20.5%
61	Polymenorrhea	20.5%
62	Postoperative Complications	20.5%
63	Cor pulmonale	20.5%
64	Sclerosis	20.5%
65	Shock	20.5%
66	Ulcer	20.5%
67	Ventricular Outflow Obstruction	20.5%
68	Hyperammonemia	20.5%
69	Hyperamylasemia	20.5%
70	Teratogenesis	20.5%
71	Ventricular Dysfunction	20.5%
72	Cardiac Death	20.5%
73	Hypovolemia	20.5%
74	Hyperuricemia	20.5%
75	Cardiomyopathies	20.5%
76	Leukoaraiosis	20.5%
77	Pleuropericarditis	20.5%
78	Dysbacteriosis	20.5%
79	Delayed Graft Function	20.5%
80	Cirrhosis	20.5%
81	Neointima	20.5%
82	Dysbiosis	20.5%
83	Aortic Valve Stenosis	20%
84	Cardiomyopathy, Dilated	20%
85	Infarction	20%
86	Postoperative Hemorrhage	20%
87	Pulmonary Valve Stenosis	20%
88	Shock, Hemorrhagic	20%
89	Systemic Inflammatory Response Syndrome	20%
90	Wolff-Parkinson-White Syndrome	19.6%
91	Myocardial Reperfusion Injury	19.4%
92	Cardiomegaly	18.6%
93	Cardiac Hypertrophy	18.6%
94	Sudden Cardiac Death	17.4%
95	Vascular Remodeling	16.7%
96	Extravasation of Diagnostic and Therapeutic Materials	16.1%
97	Neoplastic Processes	16.1%
98	Hypertrophic Cardiomyopathy	16%
99	Hypertrophic obstructive cardiomyopathy	16%
100	Shock, Cardiogenic	15.8%
101	Necrosis	15.5%
102	Granulomatosis, Orofacial	15.5%
103	Pigmentation Disorders	15.5%
104	Respiratory Aspiration	15.5%
105	Tricuspid Atresia	15.5%
106	Arrhythmogenic Right Ventricular Dysplasia	15.5%
107	Acantholysis	15.3%
108	Chromosome Aberrations	15.3%
109	Dehydration	15.3%
110	Granuloma	15.3%
111	Leukocytosis	15.3%
112	Reperfusion Injury	15.3%
113	Pleocytosis	15.3%
114	Vasoplegia	15.3%
115	Rheumatic Heart Disease	15.1%
116	Supravalvular aortic stenosis	14.8%
117	Sudden infant death syndrome	14.8%
118	Menorrhagia	13.8%
119	Chromosomal Instability	13.4%
120	Acute Disease	13.3%
121	Acute-Phase Reaction	13.3%
122	Amenorrhea	13.3%
123	Aortic Valve Insufficiency	13.3%
124	Restrictive cardiomyopathy	13.3%
125	Chronic disease	13.3%
126	Coronary heart disease	13.3%
127	Critical Illness	13.3%
128	Sudden death	13.3%
129	Edema, Cardiac	13.3%
130	Endocardial Fibroelastosis	13.3%
131	Fat necrosis	13.3%
132	Gangrene	13.3%
133	Graft Occlusion, Vascular	13.3%
134	Granuloma, Plasma Cell	13.3%
135	Heart Rupture, Post-Infarction	13.3%
136	Hematoma	13.3%
137	Iatrogenic Disease	13.3%
138	Mitral Valve Insufficiency	13.3%
139	Mitral Valve Stenosis	13.3%
140	Multiple Organ Failure	13.3%
141	Myocardial Infarction	13.3%
142	Myocarditis	13.3%
143	Oligomenorrhea	13.3%
144	Pericarditis, Constrictive	13.3%
145	Premenstrual syndrome	13.3%
146	Pulmonary Valve Insufficiency	13.3%
147	Recurrence	13.3%
148	Retrograde Degeneration	13.3%
149	Retroperitoneal fibrosis	13.3%
150	Serositis	13.3%
151	Subcutaneous Emphysema	13.3%
152	Surgical Wound Dehiscence	13.3%
153	Syndrome	13.3%
154	Tricuspid Valve Insufficiency	13.3%
155	Tricuspid Valve Stenosis	13.3%
156	Wallerian Degeneration	13.3%
157	Pyogenic granuloma	13.3%
158	Exsanguination	13.3%
159	Disease Progression	13.3%
160	Ventricular Dysfunction, Left	13.3%
161	Right Ventricular Dysfunction	13.3%
162	Seroma	13.3%
163	Incisional hernia	13.3%
164	Premenstrual Tension	13.3%
165	Delayed Emergence from Anesthesia	13.3%
166	Infant Death	13.3%
167	Endomyocardial Fibrosis	13.3%
168	Carditis	13.3%
169	Anastomotic Leak	13.3%
170	Intraoperative Awareness	13.3%
171	Acute Coronary Syndrome	13.3%
172	Heart Failure, Systolic	13.3%
173	Heart Failure, Diastolic	13.3%
174	jaundice	13.3%
175	Genomic Instability	12.7%
176	Pain, Postoperative	12.4%
177	Left Ventricular Hypertrophy	12.4%
178	Right Ventricular Hypertrophy	12.4%
179	No-Reflow Phenomenon	12.4%
180	Angina Pectoris	12.2%
181	Azotemia	12%
182	Dysmenorrhea	11.9%
183	Failed Back Surgery Syndrome	11.9%
184	Signs and Symptoms	11.9%
185	Vascular Diseases	11.9%
186	Pathological Conditions, Anatomical	11.9%
187	Muscle Weakness	11.9%
188	Postoperative Nausea and Vomiting	11.8%
189	Eye Hemorrhage	11.1%
190	Endotoxic shock	10.8%
191	Septic Shock	10.8%
192	Toxic Shock Syndrome	10.8%
193	Hemoptysis	10.8%
194	Kounis Syndrome	10.8%
195	Primary Graft Dysfunction	10.7%
196	Ecchymosis	10.7%
197	Petechiae	10.7%
198	Purpura	10.7%
199	Aortic coarctation	10.6%
200	Cor Triatriatum	10.6%
201	Coronary Vessel Anomalies	10.6%
202	Patent ductus arteriosus	10.6%
203	Ebstein Anomaly	10.6%
204	Heart Septal Defects	10.6%
205	Tetralogy of Fallot	10.6%
206	Transposition of Great Vessels	10.6%
207	Hypoplastic Left Heart Syndrome	10.6%
208	Asphyxia	10.5%
209	Coronary Aneurysm	10.5%
210	Granuloma, Respiratory Tract	10.5%
211	Shock, Traumatic	10.5%
212	Cardiotoxicity	10.3%
213	Bacterial Endocarditis	10.2%
214	Disease susceptibility	10.2%
215	Fetal Death	10.2%
216	Foreign-Body Reaction	10.2%
217	Gastrointestinal Hemorrhage	10.2%
218	Hemarthrosis	10.2%
219	Hemoperitoneum	10.2%
220	Hemothorax	10.2%
221	Neoplasm Invasiveness	10.2%
222	Neoplasm Metastasis	10.2%
223	Neoplasm Recurrence, Local	10.2%
224	Prosthesis Failure	10.2%
225	Injection Site Reaction	10.2%
226	Retrobulbar Hemorrhage	10.2%
227	Aseptic Necrosis of Bone	10.2%
228	Peritoneal Fibrosis	10.2%
229	Carcinogenesis	10.2%
230	Neurogenic Inflammation	10.2%
231	Perinatal death	10.2%
232	Infusion site reaction	10.2%
233	Nephrogenic Fibrosing Dermopathy	10.2%
234	Corneal Endothelial Cell Loss	10.2%
235	Encapsulating Peritoneal Sclerosis	10.2%
236	Suppuration	10.2%
237	Nephrogenic Systemic Fibrosis	10.2%
238	Metastasis	10.2%
239	Dental Pulp Necrosis	10%
240	Granuloma, Foreign-Body	10%
241	Mediastinal Emphysema	10%
242	Surgical Wound Infection	10%
243	Facies	10%
244	Embryo Loss	10%
245	Diabetic Cardiomyopathies	10%
246	Dyspnea, Paroxysmal	9.9%
247	Afferent Loop Syndrome	9.9%
248	Cardiomyopathy, Alcoholic	9.9%
249	Sex Chromosome Aberrations	9.9%
250	Short Bowel Syndrome	9.9%
251	Uterine hemorrhage	9.9%
252	Tissue Adhesions	9.9%
253	Aortic Valve Prolapse	9.9%
254	Tricuspid Valve Prolapse	9.9%
255	Hematoma, Epidural, Spinal	9.9%
256	Takotsubo Cardiomyopathy	9.9%
257	Chagas Cardiomyopathy	9.9%
258	Jaundice, Obstructive	9.8%
259	Coronary Occlusion	9.8%
260	Microvascular Angina	9.8%
261	Coronary Stenosis	9.8%
262	ST segment elevation myocardial infarction	9.8%
263	Chromosome Fragility	9.8%
264	Coronary Thrombosis	9.8%
265	Coronary Artery Disease	9.8%
266	Carcinoid Heart Disease	9.8%
267	Angina, Unstable	9.3%
268	Epistaxis	9.1%
269	Pregnancy Complications, Cardiovascular	8.9%
270	Cardiovascular Abnormalities	8.9%
271	Dextrocardia	8.8%
272	Trisomy	8.4%
273	Drowning	8.3%
274	Hematoma, Subdural	8.3%
275	Hematoma, Epidural, Cranial	8.3%
276	Hematoma, Subdural, Spinal	8.2%
277	Coronary Restenosis	8.1%
278	Fetal Growth Retardation	8.1%
279	DNA Degradation, Necrotic	8.1%
280	Aneuploidy	8.1%
281	Polyploidy	8.1%
282	Microsatellite Instability	8.1%
283	Cicatrix	8%
284	Hematuria	7.9%
285	Granuloma Annulare	7.9%
286	Chromosome Breakage	7.9%
287	Brain Death	7.9%
288	Hematemesis	7.9%
289	Purpura Fulminans	7.8%
290	Angina Pectoris, Variant	7.8%
291	Aortopulmonary Septal Defect	7.8%
292	Double Outlet Right Ventricle	7.8%
293	Endocardial Cushion Defects	7.8%
294	Subarachnoid Hemorrhage	7.8%
295	Myocardial bridging	7.8%
296	Cerebral Hemorrhage	7.8%
297	Aorticopulmonary Septal Defect	7.8%
298	Cross Infection	7.6%
299	Hyphema	7.6%
300	Intermittent Claudication	7.6%
301	Retinal Neovascularization	7.6%
302	Septicemia	7.6%
303	Vitreous Hemorrhage	7.6%
304	Sepsis	7.6%
305	Purpura, Hyperglobulinemic	7.5%
306	Abscess	7.4%
307	Empyema	7.4%
308	Femur Head Necrosis	7.4%
309	Fetal Resorption	7.4%
310	Lymphatic Metastasis	7.4%
311	Neoplasms, Unknown Primary	7.4%
312	Peptic Ulcer Hemorrhage	7.4%
313	Leukemic Infiltration	7.4%
314	Premenstrual Dysphoric Disorder	7.4%
315	Choroidal Neovascularization	7.4%
316	Neoplasm Micrometastasis	7.4%
317	Dumping Syndrome	7.4%
318	Cicatrix, Hypertrophic	7.4%
319	Metrorrhagia	7.3%
320	Arteriovenous fistula	7%
321	Hematoma, Subdural, Intracranial	6.9%
322	Hematoma, Subdural, Chronic	6.9%
323	Hematoma, Subdural, Acute	6.9%
324	Aneurysm	6.8%
325	Angiomatosis	6.8%
326	Aortic Diseases	6.8%
327	Arterial Occlusive Diseases	6.8%
328	Asthenia	6.8%
329	Body Temperature Changes	6.8%
330	Calculi	6.8%
331	Cyanosis	6.8%
332	Edema	6.8%
333	Failure to Thrive	6.8%
334	Fatigue	6.8%
335	Feminization	6.8%
336	Fetal Distress	6.8%
337	Hernia	6.8%
338	Hyperemia	6.8%
339	Hypertrophy	6.8%
340	Hypotension	6.8%
341	Motion Sickness	6.8%
342	Nails, Malformed	6.8%
343	polyps	6.8%
344	Rupture, Spontaneous	6.8%
345	Signs and Symptoms, Digestive	6.8%
346	Signs and Symptoms, Respiratory	6.8%
347	Skin Manifestations	6.8%
348	Superior Vena Cava Syndrome	6.8%
349	Telangiectasis	6.8%
350	Vasculitis	6.8%
351	Venous Insufficiency	6.8%
352	Peripheral Vascular Diseases	6.8%
353	Embolism and Thrombosis	6.8%
354	Angiodysplasia	6.8%
355	Chills	6.8%
356	Lassitude	6.8%
357	Enterocele	6.8%
358	Atheroma	6.8%
359	Capillary Leak Syndrome	6.8%
360	Pseudophakia	6.8%
361	Urological Manifestations	6.8%
362	Stenosis	6.8%
363	Facial asymmetry	6.8%
364	Mobility Limitation	6.8%
365	Prehypertension	6.8%
366	Somnolence	6.8%
367	Plaque, Amyloid	6.8%
368	Plaque, Atherosclerotic	6.8%
369	Giant Cell Epulis	6.8%
370	Aortic Aneurysm	6.7%
371	Aortitis	6.7%
372	Leriche Syndrome	6.7%
373	Noonan Syndrome	6.7%
374	Periphlebitis	6.7%
375	Phlebitis	6.7%
376	Thromboangiitis Obliterans	6.7%
377	Micronuclei, Chromosome-Defective	6.5%
378	Phantom pain	6.5%
379	Phantom Limb Pain	6.5%
380	Viremia	6.5%
381	Parasitemia	6.5%
382	Truncus Arteriosus, Persistent	6.5%
383	Retinal Hemorrhage	6.1%
384	Subacute Bacterial Endocarditis	6.1%
385	Choroid Hemorrhage	6%
386	Embolism, Amniotic Fluid	6%
387	Melena	6%
388	Marfan Syndrome	6%
389	Postpartum Hemorrhage	6%
390	Gingival Hemorrhage	5.9%
391	Keloid	5.9%
392	Monosomy	5.9%
393	Tetraploidy	5.9%
394	Stillbirth	5.9%
395	Abdominal Pain	5.8%
396	Postphlebitic Syndrome	5.8%
397	Subacute Combined Degeneration	5.8%
398	Retinal Vein Occlusion	5.8%
399	Thrombocytopenic purpura	5.8%
400	Eosinophilic Granuloma	5.7%
401	Thrombophlebitis	5.5%
402	Cyst	5.4%
403	Eye Manifestations	5.4%
404	Neurologic Manifestations	5.4%
405	Vascular System Injuries	5.4%
406	Livedo Reticularis	5.3%
407	Malignant Atrophic Papulosis	5.3%
408	Shwartzman Phenomenon	5.3%
409	May-Thurner Syndrome	5.3%
410	Basal Ganglia Hemorrhage	5.2%
411	Compartment syndromes	5.2%
412	Hepatic Veno-Occlusive Disease	5.2%
413	Leukoplakia	5.2%
414	Peliosis Hepatis	5.2%
415	Varicocele	5.2%
416	Reticulocytosis	5.2%
417	Airway Remodeling	5.2%
418	Blue Toe Syndrome	5.1%
419	Cerebrovascular Disorders	5.1%
420	Diabetic Angiopathies	5.1%
421	Splenic Infarction	5.1%
422	Cerebrovascular Insufficiency	5.1%
423	Vascular Neoplasms	5.1%
424	Ventricular Remodeling	5.1%
425	Spinal Cord Vascular Diseases	5.1%
426	Alopecia	5%
427	Hemorrhoids	5%
428	Thoracic Outlet Syndrome	5%
429	Androgenetic Alopecia	5%
430	Cellulitis	5%
431	Kernicterus	5%
432	Bacteremia	5%
433	Cell Transformation, Viral	5%
434	Aortic Rupture	5%
435	Renal Colic	5%
436	Fungemia	5%
437	Aortic Aneurysm, Abdominal	4.9%
438	Aortic Aneurysm, Thoracic	4.9%
439	Eye pain	4.7%
440	Muscular Atrophy	4.6%
441	Purpura, Thrombotic Thrombocytopenic	4.6%
442	Intracranial Embolism and Thrombosis	4.6%
443	Carotid Artery Thrombosis	4.6%
444	Putaminal Hemorrhage	4.6%
445	Carotid Stenosis	4.6%
446	Intracranial Aneurysm	4.6%
447	Abdomen, Acute	4.5%
448	Aneurysm, Dissecting	4.4%
449	Anorexia	4.4%
450	Anoxia	4.4%
451	Arteriosclerosis	4.4%
452	Arteritis	4.4%
453	Constipation	4.4%
454	Diarrhea	4.4%
455	Dyspepsia	4.4%
456	Embolism	4.4%
457	Eructation	4.4%
458	Erythromelalgia	4.4%
459	Fever	4.4%
460	Fibromuscular Dysplasia	4.4%
461	Flatulence	4.4%
462	Flushing	4.4%
463	Halitosis	4.4%
464	Heartburn	4.4%
465	Diaphragmatic Hernia	4.4%
466	Hiccough	4.4%
467	Hypercalciuria	4.4%
468	Hypercapnia	4.4%
469	Hyperphagia	4.4%
470	Malignant Hypertension	4.4%
471	Intestinal Polyps	4.4%
472	Nausea	4.4%
473	Pallor	4.4%
474	Psychophysiologic Disorders	4.4%
475	Raynaud Disease	4.4%
476	Splenomegaly	4.4%
477	Thromboembolism	4.4%
478	Thrombosis	4.4%
479	Vomiting	4.4%
480	Hypocapnia	4.4%
481	Essential Hypertension	4.4%
482	Aneurysm, Ruptured	4.4%
483	Iliac Aneurysm	4.4%
484	Dyschezia	4.4%
485	Pulmonary artery stenosis	4.4%
486	Hypoxia	4.4%
487	Hyperoxia	4.4%
488	White Coat Hypertension	4.4%
489	Systemic Vasculitis	4.4%
490	Lower Urinary Tract Symptoms	4.4%
491	Hypoxemia	4.4%
492	Urinoma	4.4%
493	Embolus	4.4%
494	Endotoxemia	4.4%
495	Moyamoya Disease	4.4%
496	Granuloma, Laryngeal	4.4%
497	Scimitar Syndrome	4.3%
498	Hand-Arm Vibration Syndrome	4.2%
499	Hypergammaglobulinemia	4.1%
500	Optic Neuropathy, Ischemic	4.1%
501	Williams Syndrome	4.1%
502	Anterior Ischemic Optic Neuropathy	4.1%
503	Mesenteric vascular insufficiency	4.1%
504	Angioedema	4%
505	Diverticulum	4%
506	Diverticulosis	4%
507	Colitis, Ischemic	4%
508	Polyarteritis Nodosa	3.9%
509	Takayasu Arteritis	3.9%
510	Intracranial Arteriosclerosis	3.9%
511	Cerebral Atherosclerosis	3.9%
512	Cerebral Arteriosclerosis	3.9%
513	Kearns-Sayre syndrome	3.8%
514	Vasculitis, Central Nervous System	3.8%
515	Autoimmune thrombocytopenia	3.7%
516	Immune thrombocytopenic purpura	3.7%
517	Philadelphia Chromosome	3.6%
518	Sarcopenia	3.6%
519	Cerebral Thrombosis	3.6%
520	Intracranial Embolism	3.6%
521	Intracranial Thrombosis	3.6%
522	Waterhouse-Friderichsen Syndrome	3.5%
523	Respiratory Tract Fistula	3.5%
524	Turner Syndrome	3.4%
525	Apnea	3.4%
526	Cheyne-Stokes Respiration	3.4%
527	Decerebrate State	3.4%
528	Dyspnea	3.4%
529	Hemiparesis	3.4%
530	Hepatomegaly	3.4%
531	Hyperventilation	3.4%
532	Meningism	3.4%
533	Mouth Breathing	3.4%
534	Paresis	3.4%
535	Parovarian Cyst	3.4%
536	Pruritus	3.4%
537	Retinal Artery Occlusion	3.4%
538	Seizures	3.4%
539	Sensation Disorders	3.4%
540	Sneezing	3.4%
541	Spermatocele	3.4%
542	Erythema	3.4%
543	Oral Fistula	3.4%
544	Complex partial seizures	3.4%
545	Retinal Vasculitis	3.4%
546	Hypertensive Retinopathy	3.4%
547	Necrolytic Migratory Erythema	3.4%
548	Tachypnea	3.4%
549	Monoparesis	3.4%
550	Cutaneous Fistula	3.4%
551	Gait Disorders, Neurologic	3.4%
552	Neuromuscular Manifestations	3.4%
553	Anterior Compartment Syndrome	3.3%
554	Mental Fatigue	3.3%
555	Hirsutism	3.3%
556	Vasculitis, Leukocytoclastic, Cutaneous	3.3%
557	Gastric Antral Vascular Ectasia	3.3%
558	Abdominal Compartment Syndrome	3.3%
559	Orthostatic intolerance	3.3%
560	Hypoventilation	3.3%
561	Carotid Artery Diseases	3.3%
562	Brain Ischemia	3.3%
563	Ectopia Cordis	3.3%
564	Hypotension, Orthostatic	3.3%
565	Cerebrovascular accident	3.3%
566	Vaginal Fistula	3.3%
567	Varicose Ulcer	3.3%
568	Rectocele	3.3%
569	Vasospasm, Intracranial	3.3%
570	Spinal Cord Ischemia	3.3%
571	Intracranial Arterial Diseases	3.3%
572	Single umbilical artery	3.3%
573	Post-Exercise Hypotension	3.3%
574	Arteriosclerosis Obliterans	3.3%
575	Atherosclerosis	3.3%
576	Back Pain	3.3%
577	Bulimia	3.3%
578	Neck Pain	3.3%
579	Chest Pain	3.3%
580	Colonic Polyps	3.3%
581	Dizziness	3.3%
582	Dysuria	3.3%
583	Air Embolism	3.3%
584	Endarteritis	3.3%
585	Facial Pain	3.3%
586	Fever of Unknown Origin	3.3%
587	Flank Pain	3.3%
588	Headache	3.3%
589	Nocturia	3.3%
590	Pain, Intractable	3.3%
591	Pelvic Pain	3.3%
592	Snoring	3.3%
593	Venous Thrombosis	3.3%
594	Deep Vein Thrombosis	3.3%
595	Chronic pain	3.3%
596	Lightheadedness	3.3%
597	Pain, Referred	3.3%
598	Prostatism	3.3%
599	Throbbing Headache	3.3%
600	Labor Pain	3.3%
601	Cancer Pain	3.3%
602	Venous Thromboembolism	3.3%
603	Nociceptive Pain	3.3%
604	Body Weight Changes	3.3%
605	Giant Cell Arteritis	3.3%
606	Temporal Arteritis	3.3%
607	Brain Infarction	3.2%
608	Candidemia	3.1%
609	Sinus Thrombosis, Intracranial	3.1%
610	Gait Ataxia	3%
611	Lemierre Syndrome	3%
612	Hoarseness	2.9%
613	Sleep Wake Disorders	2.9%
614	Kartagener Syndrome	2.9%
615	Subarachnoid Hemorrhage, Traumatic	2.9%
616	Carotid Artery, Internal, Dissection	2.9%
617	CREST Syndrome	2.9%
618	Body Weight	2.8%
619	Pupil Disorders	2.8%
620	Neurobehavioral Manifestations	2.8%
621	Cavernous Sinus Thrombosis	2.8%
622	Sagittal Sinus Thrombosis	2.8%
623	Vertebral Artery Dissection	2.8%
624	Infarction, Middle Cerebral Artery	2.8%
625	Infarction, Anterior Cerebral Artery	2.8%
626	Infarction, Posterior Cerebral Artery	2.8%
627	Nasal Polyps	2.7%
628	Emaciation	2.7%
629	Low Back Pain	2.7%
630	Visceral Pain	2.7%
631	Mesenteric Vascular Occlusion	2.7%
632	Mucocutaneous Lymph Node Syndrome	2.7%
633	Pleural Rub	2.7%
634	Rales	2.7%
635	Respiratory Sounds	2.7%
636	Rhonchi	2.7%
637	Stridor	2.7%
638	Wheezing	2.7%
639	Asterixis	2.7%
640	Ballismus	2.7%
641	Diabetic Retinopathy	2.7%
642	Sturge-Weber Syndrome	2.7%
643	Vertigo	2.7%
644	Cerebral Infarction	2.7%
645	Brain Stem Infarctions	2.7%
646	Pain	2.7%
647	Ache	2.7%
648	Renal hypertension	2.6%
649	Meningocele	2.6%
650	Oliguria	2.6%
651	Polyuria	2.6%
652	Proteinuria	2.6%
653	Renal Artery Obstruction	2.6%
654	Renal Artery Stenosis	2.6%
655	Urinary Calculi	2.6%
656	Encephalocele	2.6%
657	Hemangioma, Cavernous	2.6%
658	Basal Ganglia Cerebrovascular Disease	2.6%
659	Vascular Headaches	2.6%
660	Scurvy	2.6%
661	Underweight	2.6%
662	Overweight	2.6%
663	Akathisia	2.6%
664	Restlessness	2.6%
665	Psychomotor Agitation	2.6%
666	Vesicovaginal Fistula	2.5%
667	Biliary Fistula	2.5%
668	Gastric Fistula	2.5%
669	Pulmonary Embolism	2.5%
670	Congenital diaphragmatic hernia	2.5%
671	Morning Sickness	2.5%
672	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.5%
673	Anosmia	2.5%
674	Ataxia	2.5%
675	Athetosis	2.5%
676	Catalepsy	2.5%
677	Dental Fistula	2.5%
678	Dystonia	2.5%
679	Hemiplegia	2.5%
680	Locked-In Syndrome	2.5%
681	Muscle Hypertonia	2.5%
682	Muscle hypotonia	2.5%
683	Myoclonus	2.5%
684	Myotonia	2.5%
685	Neuralgia	2.5%
686	Oroantral Fistula	2.5%
687	Paraplegia	2.5%
688	Pseudobulbar Palsy	2.5%
689	Quadriplegia	2.5%
690	Spasm	2.5%
691	Spastic Paraplegia	2.5%
692	Status Epilepticus	2.5%
693	Taste Disorders	2.5%
694	Tremor	2.5%
695	Monoplegia	2.5%
696	Hypokinesia	2.5%
697	Gastroparesis	2.5%
698	Paraparesis	2.5%
699	Bradykinesia	2.5%
700	Waxy flexibility	2.5%
701	Action Tremor	2.5%
702	Resting Tremor	2.5%
703	Dysosmia	2.5%
704	Quadriparesis	2.5%
705	Olfaction Disorders	2.5%
706	Myokymia	2.5%
707	Somatosensory Disorders	2.5%
708	Neuropathic pain	2.5%
709	Hyperkinesia	2.5%
710	Intention tremor	2.5%
711	Rectal Prolapse	2.5%
712	Uterine Prolapse	2.5%
713	Vaginal Prolapse	2.5%
714	Cachexia	2.5%
715	Cerebral Arterial Diseases	2.4%
716	Vertebrobasilar Insufficiency	2.4%
717	Carotid Artery Injuries	2.4%
718	Anterior Spinal Artery Syndrome	2.4%
719	Basilar Artery Stenosis	2.4%
720	Vertebral Artery Stenosis	2.4%
721	Intracranial Hemorrhage, Hypertensive	2.4%
722	Transient Cerebral Ischemia	2.4%
723	Weight Gain	2.4%
724	Gait Apraxia	2.4%
725	Lateral Medullary Syndrome	2.4%
726	Voice Disorders	2.3%
727	Voice Disturbance	2.3%
728	Gagging	2.2%
729	Dural Arteriovenous Fistula	2.2%
730	Ischemic contracture	2.2%
731	Angioedemas, Hereditary	2.2%
732	Leukoplakia, Oral	2.2%
733	Cryoglobulinemia	2.2%
734	Leukomalacia, Periventricular	2.2%
735	Diabetic Foot	2.2%
736	Hepatic Vein Thrombosis	2.1%
737	Umbilical hernia	2.1%
738	Toothache	2.1%
739	Budd-Chiari Syndrome	2.1%
740	Alexia	2.1%
741	Dyslexia	2.1%
742	Vision Disorders	2.1%
743	Metamorphopsia	2.1%
744	Visual Impairment	2.1%
745	Hyperemesis Gravidarum	2.1%
746	Pulmonary Infarction	2.1%
747	Bronchial Fistula	2%
748	Dysgeusia	2%
749	Formication	2%
750	Hyperalgesia	2%
751	Hyperesthesia	2%
752	Hypesthesia	2%
753	Language Disorders	2%
754	Metatarsalgia	2%
755	Numbness	2%
756	Pancreatic Fistula	2%
757	Paresthesia	2%
758	Paraparesis, Spastic	2%
759	Trismus	2%
760	Epilepsia Partialis Continua	2%
761	Hypogeusia	2%
762	Brown-Sequard Syndrome	2%
763	Lockjaw	2%
764	Allodynia	2%
765	Ageusia	2%
766	Subclavian Steal Syndrome	2%
767	Alice in Wonderland Syndrome	2%
768	Anisocoria	2%
769	Confusion	2%
770	Facial paralysis	2%
771	Intestinal Fistula	2%
772	Lethargy	2%
773	Memory Disorders	2%
774	Muscle Cramp	2%
775	Perceptual Disorders	2%
776	Psychomotor Disorders	2%
777	Tonic Pupil	2%
778	Anhedonia	2%
779	Disorientation	2%
780	Gastroschisis	2%
781	Enterocutaneous Fistula	2%
782	Fetal Hypoxia	2%
783	Facial Paresis	2%
784	Memory Loss	2%
785	Hemisensory Neglect	2%
786	Dysacusis	2%
787	Mastodynia	2%
788	Respiratory Paralysis	2%
789	Salivary Gland Fistula	2%
790	Chorea	2%
791	Cystocele	2%
792	Tetany	2%
793	Urinary Incontinence	2%
794	Breakthrough Pain	2%
795	Albuminuria	2%
796	Hemoglobinuria	2%
797	Hypertension, Renovascular	2%
798	Hypoxia-Ischemia, Brain	2%
799	Hereditary Angioedema Type III	1.9%
800	Hereditary Angioedema Types I and II	1.9%
801	Jet Lag Syndrome	1.9%
802	Reflex, Abnormal	1.9%
803	Hyporeflexia	1.9%
804	Hyperreflexia	1.9%
805	Shy-Drager Syndrome	1.9%
806	Birth Weight	1.8%
807	Agraphia	1.8%
808	Anomia	1.8%
809	Cluttering	1.8%
810	Language Development Disorders	1.8%
811	Speech Disorders	1.8%
812	Syncope	1.8%
813	Stupor	1.8%
814	Dysgraphia	1.8%
815	Presyncope	1.8%
816	Dyslalia	1.8%
817	Dementia, Vascular	1.8%
818	Aphasia	1.7%
819	Articulation Disorders	1.7%
820	Echolalia	1.7%
821	Stuttering	1.7%
822	Dysphasia	1.7%
823	Consciousness Disorders	1.7%
824	Mental Retardation	1.7%
825	Depressed Level of Consciousness	1.7%
826	Mental deficiency	1.7%
827	Intellectual Disability	1.7%
828	Catatonia	1.7%
829	Musculoskeletal Pain	1.7%
830	Ophthalmoplegia	1.7%
831	External Ophthalmoplegia	1.7%
832	Dysarthria	1.7%
833	Behcet Syndrome	1.7%
834	Diplopia	1.7%
835	Muscle Rigidity	1.7%
836	Muscle Spasticity	1.7%
837	Scotoma	1.7%
838	Photophobia	1.7%
839	Cogwheel Rigidity	1.7%
840	Hemifacial Spasm	1.7%
841	Amaurosis	1.7%
842	Blindness	1.7%
843	Nuchal Rigidity	1.7%
844	Aphonia	1.7%
845	Arthralgia	1.7%
846	Sleep Deprivation	1.7%
847	Polyarthralgia	1.7%
848	Dysphonia	1.7%
849	Waldenstrom Macroglobulinemia	1.7%
850	Multiple Myeloma	1.7%
851	Granulomatosis with polyangiitis	1.7%
852	Pituitary Apoplexy	1.6%
853	Agnosia	1.6%
854	Apraxias	1.6%
855	Cerebrospinal Fluid Otorrhea	1.6%
856	Cerebrospinal Fluid Rhinorrhea	1.6%
857	Hallucinations	1.6%
858	Hemianopsia	1.6%
859	Hyperacusis	1.6%
860	Tinnitus	1.6%
861	Visual Agnosia	1.6%
862	Anosognosia	1.6%
863	Wernicke-Korsakoff Syndrome	1.6%
864	Phonophobia	1.6%
865	Hearing Loss	1.6%
866	Cerebellar Ataxia	1.6%
867	Torticollis	1.6%
868	Obesity	1.6%
869	Sciatica	1.6%
870	Urge Incontinence	1.6%
871	Tardive Dyskinesia	1.6%
872	Cerebral Amyloid Angiopathy	1.6%
873	Lupus Vasculitis, Central Nervous System	1.5%
874	Ataxia Telangiectasia	1.5%
875	Pseudoxanthoma Elasticum	1.5%
876	Hydrops Fetalis	1.5%
877	Amaurosis Fugax	1.5%
878	Blindness, Cortical	1.5%
879	Dyscalculia	1.5%
880	Deafness	1.5%
881	Hearing Loss, Sudden	1.5%
882	Gerstmann Syndrome	1.5%
883	Hearing Loss, Bilateral	1.5%
884	Hearing Loss, High-Frequency	1.5%
885	Hearing Loss, Mixed Conductive-Sensorineural	1.5%
886	Prosopagnosia	1.5%
887	Apraxia, Ideomotor	1.5%
888	Persistent Vegetative State	1.5%
889	Charles Bonnet Syndrome	1.5%
890	Hearing Loss, Unilateral	1.5%
891	Complete Hearing Loss	1.5%
892	Alien Hand Syndrome	1.5%
893	Deaf Mutism	1.5%
894	Fetal Weight	1.4%
895	Vocal Cord Paralysis	1.4%
896	Urinary Bladder Fistula	1.4%
897	Rheumatoid Vasculitis	1.4%
898	Mutism	1.4%
899	Selective Mutism	1.4%
900	Tinea Pedis	1.4%
901	Amblyopia	1.4%
902	Amnesia	1.4%
903	Delirium	1.4%
904	Horner Syndrome	1.4%
905	Dissociative Amnesia	1.4%
906	Color blindness	1.4%
907	Global Amnesia	1.4%
908	Rectal Fistula	1.4%
909	Anal Fistula	1.4%
910	Shoulder Pain	1.4%
911	Pediatric Obesity	1.3%
912	Alexia, Pure	1.3%
913	Dyskinesia, Drug-Induced	1.3%
914	Alcohol Withdrawal Seizures	1.2%
915	Retrograde amnesia	1.2%
916	Amnesia, Anterograde	1.2%
917	Akathisia, Drug-Induced	1.2%
918	Myalgia	1.2%
919	Kidney Calculi	1.1%
920	Ureteral Calculi	1.1%
921	Amnesia, Transient Global	1.1%
922	Auditory Perceptual Disorders	1%
923	Ophthalmoplegic Migraine	0.9%
924	Progressive supranuclear palsy	0.9%
925	Brain Hemorrhage, Traumatic	0.9%
926	MELAS Syndrome	0.9%
927	Fabry Disease	0.7%

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