MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Gynecomastia

(UMLS:C0018418)

Definition:: Enlargement of the BREAST in the males, caused by an excess of ESTROGENS. Physiological gynecomastia is normally observed in NEWBORNS; ADOLESCENT; and AGING males.
UMLS ID:: C0018418
MeSH ID:: D006177

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.090.875

Synonym(s)

Gynecomastia

Enlarged male breast

GYNAECOMASTIA

GYNECOMASTIA

Gynaecomastia

Gynaecomazia

Gynecomastia of non-human mammary gland

Gynecomazia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Bromocriptine	3079888	CTD
2	Chlorotrianisene	1182631	CTD
3	Cimetidine	View details 682299 3654561 6150641 6753681 6835285 7771409	CTD
4	Clonidine	16401171	CTD
5	Cyproterone Acetate	6205409	CTD
6	Diethylstilbestrol	1182631 11502463	CTD
7	Domperidone	16960712	CTD
8	Endosulfan	28935589	CTD
9	Estrone	15483104	CTD
10	Finasteride	8881946 15151957	CTD
11	Flutamide	15715105	CTD
12	Genistein	23770295	CTD
13	Metoclopramide	319356	CTD
14	Mirtazapine	15105766	CTD
15	Norinyl	1182631	CTD
16	Omeprazole	1392958 1682578 7771409	CTD
17	Phytoestrogens	23770295	CTD
18	Ranitidine	3984961	CTD
19	Risperidone	9696519 16633146	CTD
20	Spironolactone	View details 4739107 17309946 21130975 22074142	CTD
21	Tamoxifen	15681525 16280763 17291610	CTD
22	bicalutamide	View details 15151957 15681525 16280763 20620411	CTD
23	daidzein	23770295	CTD
24	haloperidol decanoate	17873694	CTD
25	secoisolariciresinol	23770295	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Breast Cyst	31.8%
2	Lactation Disorder	31.1%
3	Mastitis	31.1%
4	Dermatitis	31%
5	Exanthema	31%
6	Facial Dermatoses	31%
7	Hair Diseases	31%
8	Hand Dermatoses	31%
9	keratoacanthoma	31%
10	Keratosis	31%
11	Nail Diseases	31%
12	Photosensitivity Disorders	31%
13	Prurigo	31%
14	Pyoderma	31%
15	Rosacea	31%
16	Sebaceous Gland Diseases	31%
17	Skin Diseases, Vesiculobullous	31%
18	Skin Ulcer	31%
19	Sweat Gland Diseases	31%
20	Skin Diseases, Papulosquamous	31%
21	Skin Diseases, Vascular	31%
22	Acneiform Eruptions	31%
23	Ocular Rosacea	31%
24	Subcorneal pustular dermatosis	31%
25	Erythematotelangiectatic Rosacea	31%
26	Papulopustular Rosacea	31%
27	Chronic Actinic Dermatitis	31%
28	Pyoderma Gangrenosum	30%
29	Lupus Erythematosus, Cutaneous	27.9%
30	Panniculitis	27.9%
31	Systemic Scleroderma	27.9%
32	Morphea	27.9%
33	Acne Vulgaris	26.7%
34	Contact Dermatitis	26.7%
35	Eczema	26.7%
36	Erythema Multiforme	26.7%
37	Intertrigo	26.7%
38	Neurodermatitis	26.7%
39	Rhinophyma	26.7%
40	Perioral Dermatitis	26.7%
41	Acne	26.7%
42	Foot Ulcer	23.1%
43	Breast Neoplasms, Male	23.1%
44	Triple Negative Breast Neoplasms	23.1%
45	Galactorrhea	22.8%
46	Foot Diseases	22%
47	Dermatitis, Phototoxic	22%
48	Pityriasis Lichenoides et Varioliformis Acuta	22%
49	Pityriasis Lichenoides	22%
50	Phototoxicity	22%
51	Skin Abnormalities	20.9%
52	Skin Diseases, Infectious	20.9%
53	Skin Neoplasms	20.9%
54	Pigmentation Disorders	20.9%
55	Lipomatosis	20.5%
56	Pruritus	20.5%
57	Erythema	20.5%
58	Necrolytic Migratory Erythema	20.5%
59	Cutaneous Fistula	20.5%
60	Nephrogenic Fibrosing Dermopathy	20.5%
61	Nephrogenic Systemic Fibrosis	20.5%
62	Dermatitis Herpetiformis	20.3%
63	Acrodermatitis	20%
64	Anhidrosis	20%
65	Cholesteatoma	20%
66	Pressure Ulcer	20%
67	Dermatitis, Atopic	20%
68	Epidermolysis Bullosa	20%
69	Folliculitis	20%
70	Foot Dermatoses	20%
71	Hypertrichosis	20%
72	Hypohidrosis	20%
73	Hypotrichosis	20%
74	Leg Ulcer	20%
75	Miliaria	20%
76	Parakeratosis	20%
77	Parapsoriasis	20%
78	Pityriasis	20%
79	Psoriasis	20%
80	Sebaceous Gland Neoplasms	20%
81	Sweet Syndrome	20%
82	Hidradenitis	20%
83	Onycholysis	20%
84	Miliaria Rubra	20%
85	Hyperpigmentation	20%
86	Porokeratosis	20%
87	Lichenoid Eruptions	20%
88	Gianotti-Crosti Syndrome	20%
89	Chloracne	20%
90	Keratoderma, Palmoplantar	20%
91	Dermatitis, Irritant	19.6%
92	Acne Conglobata	19.6%
93	Connective Tissue Diseases	18.5%
94	Panniculitis, Lupus Erythematosus	18.4%
95	Xeroderma Pigmentosum	17.9%
96	Necrobiosis Lipoidica Diabeticorum	17.9%
97	Lupus Erythematosus, Discoid	17.8%
98	Scleroderma, Limited	17.8%
99	Dermatitis, Photoallergic	17.5%
100	Urticaria Pigmentosa	17.1%
101	Xeroderma	16.2%
102	Dermatomyositis	16.2%
103	Diaper Rash	16.1%
104	Dermatitis, Occupational	15.5%
105	Cutis Laxa	15.3%
106	Mastocytosis	15.1%
107	Lichen Planus	14.8%
108	Melanosis	14.8%
109	Chloasma	14.8%
110	Pityriasis Rosea	14.8%
111	Pityriasis Rubra Pilaris	14.8%
112	Vitiligo	14.8%
113	Dermatitis, Allergic Contact	14.8%
114	Lichen Nitidus	14.8%
115	Papillon-Lefevre Disease	14.6%
116	Erythema Induratum	14.4%
117	Erythema Infectiosum	14.1%
118	Exanthema Subitum	14%
119	Erythema Nodosum	13.7%
120	Carcinoma, Lobular	13.7%
121	Acantholysis	13.6%
122	Actinic keratosis	13.6%
123	Pemphigoid, Benign Mucous Membrane	13.6%
124	Pemphigus	13.6%
125	Piedra	13.6%
126	Sunburn	13.6%
127	Argyria	13.3%
128	Ectodermal Dysplasia	13.3%
129	Hirsutism	13.3%
130	Urticaria	13.3%
131	Aplasia Cutis Congenita	13.3%
132	Adiposis Dolorosa	13.2%
133	Pruritus Vulvae	13.2%
134	Mastocytoma	13.1%
135	Pruritus Ani	13.1%
136	Tinea Capitis	12.7%
137	Onychomycosis	12.7%
138	Toxic Epidermal Necrolysis	12.6%
139	Stevens-Johnson Syndrome	12.6%
140	Pseudoxanthoma Elasticum	12.6%
141	Granuloma Annulare	12.4%
142	Acanthosis Nigricans	12.2%
143	Alopecia Areata	12.2%
144	Lentigo	12.2%
145	Ecthyma	11.5%
146	Hyperkeratosis, Epidermolytic	11%
147	Collagen Diseases	10.3%
148	Mixed Connective Tissue Disease	10.3%
149	Mucinoses	10.3%
150	Dermatomycoses	10.2%
151	Mucocutaneous Lymph Node Syndrome	10.2%
152	Skin Diseases, Bacterial	10.2%
153	Alopecia	10.1%
154	Sweating, Gustatory	10.1%
155	Androgenetic Alopecia	10.1%
156	Auriculotemporal Syndrome	10.1%
157	Drug Eruptions	10%
158	Lipodystrophy	10%
159	Livedo Reticularis	10%
160	Malignant Atrophic Papulosis	10%
161	Behcet Syndrome	10%
162	Lice Infestations	9.9%
163	Varicose Ulcer	9.9%
164	Polyarteritis Nodosa	9.8%
165	Takayasu Arteritis	9.8%
166	Ichthyosis, X-Linked	9.8%
167	Hidradenitis Suppurativa	9.8%
168	Sjogren-Larsson Syndrome	9.8%
169	Tinea Pedis	8.9%
170	Albinism	8.7%
171	Erythema Chronicum Migrans	8.5%
172	Lichen Planus, Oral	8.4%
173	Nail-Patella Syndrome	8.2%
174	Porphyrias, Hepatic	8.1%
175	Larva Migrans	7.6%
176	Leishmaniasis	7.6%
177	Molluscum Contagiosum	7.6%
178	Angioedema	7.5%
179	Onchocerciasis	7.5%
180	Chromoblastomycosis	7.4%
181	Dermatophytosis	7.4%
182	Sporotrichosis	7.4%
183	Tinea	7.4%
184	Tinea Versicolor	7.4%
185	Trichophytosis	7.4%
186	Hyalohyphomycosis	7.4%
187	Mycetoma	7.3%
188	Cartilage Diseases	7.3%
189	Rheumatism	7.3%
190	Chondromalacia	7.3%
191	Acute Generalized Exanthematous Pustulosis	7.3%
192	Lupus Erythematosus, Systemic	7%
193	Overlap syndrome	7%
194	Scleromyxedema	6.7%
195	Leishmaniasis, Cutaneous	6.1%
196	Eczema Herpeticum	6.1%
197	Warts	6.1%
198	Fusariosis	6%
199	Candidiasis, Chronic Mucocutaneous	5.9%
200	Cutaneous Candidiasis	5.9%
201	Erysipelas	5.9%
202	Serum Sickness	5.9%
203	Staphylococcal Skin Infections	5.9%
204	Variegate Porphyria	5.9%
205	Acute intermittent porphyria	5.9%
206	Porphyria Cutanea Tarda	5.9%
207	Erythrasma	5.9%
208	Arthritis, Psoriatic	5.8%
209	CREST Syndrome	5.6%
210	Hereditary Angioedema Type III	5.4%
211	Hereditary Angioedema Types I and II	5.4%
212	Dupuytren Contracture	5%
213	Angioedemas, Hereditary	5%
214	Epidermodysplasia Verruciformis	4.9%
215	Herpes Labialis	4.9%
216	Giant Cell Arteritis	4.9%
217	Temporal Arteritis	4.9%
218	Diabetic Foot	4.9%
219	Staphylococcal Scalded Skin Syndrome	4.8%
220	Mesenteric Panniculitis	4.5%
221	Panniculitis, Peritoneal	4.5%
222	Tietze's Syndrome	4.5%
223	Orbital Cellulitis	4.5%
224	Myxoid cyst	4.5%
225	Peutz-Jeghers Syndrome	4.5%
226	Myxedema	4.4%
227	carbuncle	4.3%
228	Blastomycosis	4.2%
229	HIV-Associated Lipodystrophy Syndrome	4.2%
230	Condylomata Acuminata	4.1%
231	Furunculosis	4.1%
232	furuncle	4.1%
233	Cellulitis	4%
234	Impetigo	4%
235	Rhinoscleroma	3.8%
236	Menkes Kinky Hair Syndrome	3.5%
237	Osteochondritis	3.4%
238	Polymyalgia Rheumatica	3.4%
239	Osteogenesis Imperfecta	3.4%
240	Keloid	3.3%
241	Noonan Syndrome	2.9%
242	Rheumatoid Arthritis	2.7%
243	Juvenile arthritis	2.7%
244	Lupus Nephritis	2.6%
245	Marfan Syndrome	2.5%
246	Rheumatoid Nodule	2.5%
247	Homocystinuria	2.4%
248	Laryngomalacia	2.3%
249	Pectus carinatum	2.3%
250	Felty Syndrome	2%
251	Bronchomalacia	2%
252	Tracheomalacia	2%
253	Rheumatoid Vasculitis	1.6%
254	Mucopolysaccharidosis III	1.6%
255	Sicca Syndrome	1.4%
256	Sjogren's Syndrome	1.4%
257	Lupus Vasculitis, Central Nervous System	1.1%
258	Mucopolysaccharidosis II	1.1%

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