MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leriche Syndrome

(UMLS:C0023370)

Definition:: A condition caused by occlusion of terminal aorta, the primary branches of the ABDOMINAL AORTA, as in aortoiliac obstruction. Leriche syndrome usually occurs in males and is characterized by IMPOTENCE, absence of a pulse in the femoral arteries, weakness and numbness in the lower back, buttocks, hips, and lower limbs.
UMLS ID:: C0023370
MeSH ID:: D007925

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.109.661|C14.907.137.427

Synonym(s)

Leriche Syndrome

AORTIC BIFURCATION SYNDROME, ACUTE

AORTIC BIFURCATION SYNDROME, CHRONIC

AORTIC OCCLUSION DISTAL CHRONIC

Aortic bifurcation embolus

Aortic bifurcation syndrome

Aortic bifurcation thrombosis syndrome

Aortoiliac obstruction

Chronic aorto-iliac occlusion syndrome

10.

EMBOLISM, AORTIC BIFURCATION

11.

LERICHE SYNDROME

12.

Leriche

13.

Leriche syndrome

14.

Leriche's syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 7		US FAERS
2	rofecoxib	FAERS: 5		OFFSIDES US FAERS
3	LCZ 696	FAERS: 3		US FAERS
4	Thalidomide	FAERS: 2		US FAERS
5	Cilostazol	FAERS: 1		US FAERS
6	Dabigatran	FAERS: 1		US FAERS
7	Metoprolol	FAERS: 1		US FAERS
8	Olanzapine	FAERS: 1		US FAERS
9	Rosiglitazone	FAERS: 1		US FAERS
10	Sunitinib	FAERS: 1		US FAERS
11	Synjardy	FAERS: 1		US FAERS
12	apixaban	FAERS: 1		US FAERS
13	Aprepitant			OFFSIDES
14	Bortezomib			OFFSIDES
15	Darunavir			OFFSIDES
16	Fluorouracil			OFFSIDES
17	Methocarbamol			OFFSIDES
18	Methysergide			SIDER
19	Pamidronate			OFFSIDES
20	Penicillin V			OFFSIDES
21	Rabeprazole			OFFSIDES
22	Tenofovir			OFFSIDES
23	Zoledronic Acid			OFFSIDES
24	azelastine			OFFSIDES
25	fludarabine phosphate			OFFSIDES
26	fludarabine			OFFSIDES
27	reviparin		8659220	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Aortic Aneurysm	53.3%
2	Aortitis	53.3%
3	Thromboangiitis Obliterans	53.3%
4	Arteriosclerosis	44.4%
5	Fibromuscular Dysplasia	44.4%
6	Pulmonary artery stenosis	44.4%
7	Malignant Atrophic Papulosis	42.7%
8	Myocardial Ischemia	41.4%
9	Aneurysm	40.9%
10	Angiomatosis	40.9%
11	Hyperemia	40.9%
12	Hypotension	40.9%
13	Superior Vena Cava Syndrome	40.9%
14	Telangiectasis	40.9%
15	Vasculitis	40.9%
16	Venous Insufficiency	40.9%
17	Peripheral Vascular Diseases	40.9%
18	Embolism and Thrombosis	40.9%
19	Angiodysplasia	40.9%
20	Capillary Leak Syndrome	40.9%
21	Prehypertension	40.9%
22	Periphlebitis	40%
23	Phlebitis	40%
24	Aortic Aneurysm, Abdominal	39.3%
25	Aortic Aneurysm, Thoracic	39.3%
26	Carotid Stenosis	38%
27	Aortic Rupture	36.5%
28	Coronary Artery Disease	35.3%
29	Postphlebitic Syndrome	34.7%
30	Retinal Vein Occlusion	34.6%
31	Retinal Artery Occlusion	33.9%
32	Moyamoya Disease	33.8%
33	Thrombophlebitis	33.2%
34	Arteriosclerosis Obliterans	33%
35	Atherosclerosis	33%
36	Vascular System Injuries	32.1%
37	Shwartzman Phenomenon	31.8%
38	Coronary Aneurysm	31.6%
39	Takayasu Arteritis	31.6%
40	Intracranial Arteriosclerosis	31.3%
41	Cerebral Atherosclerosis	31.3%
42	Cerebral Arteriosclerosis	31.3%
43	Compartment syndromes	31%
44	Hepatic Veno-Occlusive Disease	31%
45	Peliosis Hepatis	31%
46	Varicocele	31%
47	Blue Toe Syndrome	30.8%
48	Cerebrovascular Disorders	30.5%
49	Diabetic Angiopathies	30.5%
50	Reperfusion Injury	30.5%
51	Splenic Infarction	30.5%
52	Cerebrovascular Insufficiency	30.5%
53	Vascular Neoplasms	30.5%
54	Spinal Cord Vascular Diseases	30.5%
55	Vasoplegia	30.5%
56	Myocardial Reperfusion Injury	30.3%
57	Hemorrhoids	30.3%
58	Thoracic Outlet Syndrome	30.3%
59	Intracranial Embolism and Thrombosis	27.6%
60	Carotid Artery Thrombosis	27.6%
61	Intracranial Aneurysm	27.5%
62	Coronary Thrombosis	27.5%
63	Mesenteric Vascular Occlusion	27%
64	Aneurysm, Dissecting	26.7%
65	Arteritis	26.7%
66	Coronary heart disease	26.7%
67	Embolism	26.7%
68	Erythromelalgia	26.7%
69	Malignant Hypertension	26.7%
70	Myocardial Infarction	26.7%
71	Raynaud Disease	26.7%
72	Thromboembolism	26.7%
73	Thrombosis	26.7%
74	Essential Hypertension	26.7%
75	Aneurysm, Ruptured	26.7%
76	Iliac Aneurysm	26.7%
77	White Coat Hypertension	26.7%
78	Systemic Vasculitis	26.7%
79	Acute Coronary Syndrome	26.7%
80	Embolus	26.7%
81	Renal Artery Obstruction	26.5%
82	Renal Artery Stenosis	26.5%
83	Hand-Arm Vibration Syndrome	25.4%
84	Intermittent Claudication	25.2%
85	Optic Neuropathy, Ischemic	24.7%
86	Anterior Ischemic Optic Neuropathy	24.7%
87	Mesenteric vascular insufficiency	24.7%
88	Arteriovenous fistula	24.5%
89	Angioedema	24%
90	Colitis, Ischemic	23.9%
91	Heart Diseases	23.8%
92	Polyarteritis Nodosa	23.7%
93	Vasculitis, Central Nervous System	23%
94	Kounis Syndrome	21.6%
95	Cerebral Thrombosis	21.4%
96	Intracranial Embolism	21.4%
97	Intracranial Thrombosis	21.4%
98	May-Thurner Syndrome	21.2%
99	Angina Pectoris	21.1%
100	Aortic Diseases	20.5%
101	Arterial Occlusive Diseases	20.5%
102	Retinal Vasculitis	20.3%
103	Hypertensive Retinopathy	20.3%
104	Embolism, Amniotic Fluid	20.1%
105	Anterior Compartment Syndrome	20%
106	Leriche Syndrome	20%
107	Vasculitis, Leukocytoclastic, Cutaneous	20%
108	Gastric Antral Vascular Ectasia	20%
109	Abdominal Compartment Syndrome	20%
110	Carotid Artery Diseases	19.8%
111	Brain Ischemia	19.8%
112	Hypotension, Orthostatic	19.8%
113	Cerebrovascular accident	19.8%
114	Varicose Ulcer	19.8%
115	Vasospasm, Intracranial	19.8%
116	Spinal Cord Ischemia	19.8%
117	Intracranial Arterial Diseases	19.8%
118	Primary Graft Dysfunction	19.8%
119	Post-Exercise Hypotension	19.8%
120	Air Embolism	19.8%
121	Endarteritis	19.8%
122	Venous Thrombosis	19.8%
123	Deep Vein Thrombosis	19.8%
124	Venous Thromboembolism	19.8%
125	Coronary Occlusion	19.7%
126	Microvascular Angina	19.7%
127	Coronary Stenosis	19.7%
128	ST segment elevation myocardial infarction	19.7%
129	Giant Cell Arteritis	19.6%
130	Temporal Arteritis	19.6%
131	Brain Infarction	19.5%
132	Scimitar Syndrome	18.7%
133	Sinus Thrombosis, Intracranial	18.4%
134	Lemierre Syndrome	18%
135	Pregnancy Complications, Cardiovascular	17.9%
136	Cardiovascular Abnormalities	17.9%
137	Subarachnoid Hemorrhage, Traumatic	17.2%
138	Carotid Artery, Internal, Dissection	17.2%
139	CREST Syndrome	17.1%
140	Cavernous Sinus Thrombosis	16.9%
141	Sagittal Sinus Thrombosis	16.9%
142	Vertebral Artery Dissection	16.9%
143	Infarction, Middle Cerebral Artery	16.8%
144	Infarction, Anterior Cerebral Artery	16.8%
145	Infarction, Posterior Cerebral Artery	16.8%
146	Coronary Restenosis	16.3%
147	Mucocutaneous Lymph Node Syndrome	16.2%
148	Diabetic Retinopathy	16.1%
149	Sturge-Weber Syndrome	16.1%
150	Cerebral Infarction	16.1%
151	Brain Stem Infarctions	16.1%
152	Livedo Reticularis	16%
153	Renal hypertension	15.9%
154	Hemangioma, Cavernous	15.8%
155	Shock, Cardiogenic	15.8%
156	Basal Ganglia Cerebrovascular Disease	15.8%
157	Vascular Headaches	15.7%
158	Scurvy	15.7%
159	Angina, Unstable	15.6%
160	Pulmonary Embolism	15.1%
161	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	15.1%
162	No-Reflow Phenomenon	14.9%
163	Cerebral Arterial Diseases	14.7%
164	Vertebrobasilar Insufficiency	14.7%
165	Carotid Artery Injuries	14.7%
166	Anterior Spinal Artery Syndrome	14.7%
167	Basilar Artery Stenosis	14.7%
168	Vertebral Artery Stenosis	14.7%
169	Intracranial Hemorrhage, Hypertensive	14.7%
170	Transient Cerebral Ischemia	14.7%
171	Lateral Medullary Syndrome	14.4%
172	Dementia, Vascular	14.4%
173	Cardiac Tamponade	13.6%
174	Endocarditis	13.6%
175	Cardiac Arrest	13.6%
176	Heart failure	13.6%
177	Pericardial effusion	13.6%
178	Pericarditis	13.6%
179	Pneumopericardium	13.6%
180	Cor pulmonale	13.6%
181	Ventricular Outflow Obstruction	13.6%
182	Ventricular Dysfunction	13.6%
183	Cardiomyopathies	13.6%
184	Pleuropericarditis	13.6%
185	Aortic Valve Stenosis	13.3%
186	Cardiomyopathy, Dilated	13.3%
187	Pulmonary Valve Stenosis	13.3%
188	Ischemic contracture	13.3%
189	Basal Ganglia Hemorrhage	13.3%
190	Angioedemas, Hereditary	13.3%
191	Tricuspid Atresia	13.3%
192	Arrhythmogenic Right Ventricular Dysplasia	13.3%
193	Cryoglobulinemia	13.2%
194	Leukomalacia, Periventricular	13.2%
195	Diabetic Foot	13.1%
196	Angina Pectoris, Variant	12.9%
197	Hepatic Vein Thrombosis	12.6%
198	Budd-Chiari Syndrome	12.6%
199	Pulmonary Infarction	12.3%
200	Subclavian Steal Syndrome	12.2%
201	Hypertension, Renovascular	11.7%
202	Subarachnoid Hemorrhage	11.7%
203	Hypoxia-Ischemia, Brain	11.7%
204	Cerebral Hemorrhage	11.7%
205	Hereditary Angioedema Type III	11.7%
206	Hereditary Angioedema Types I and II	11.7%
207	Putaminal Hemorrhage	11.4%
208	Bacterial Endocarditis	11.4%
209	Shy-Drager Syndrome	11.2%
210	Purpura, Hyperglobulinemic	11.2%
211	Hypertrophic Cardiomyopathy	10.7%
212	Hypertrophic obstructive cardiomyopathy	10.7%
213	Heart Block	10.7%
214	Tachycardia	10.7%
215	Tachyarrhythmia	10.7%
216	Aortic coarctation	10.6%
217	Cor Triatriatum	10.6%
218	Coronary Vessel Anomalies	10.6%
219	Patent ductus arteriosus	10.6%
220	Ebstein Anomaly	10.6%
221	Heart Septal Defects	10.6%
222	Tetralogy of Fallot	10.6%
223	Transposition of Great Vessels	10.6%
224	Hypoplastic Left Heart Syndrome	10.6%
225	Cardiac Output, High	10.3%
226	Myocardial Stunning	10.3%
227	Low Cardiac Output Syndrome	10.3%
228	Cardiomegaly	10.2%
229	Postpericardiotomy Syndrome	10.2%
230	Cardiac Hypertrophy	10.2%
231	Rheumatic Heart Disease	10%
232	Behcet Syndrome	10%
233	Waldenstrom Macroglobulinemia	9.9%
234	Multiple Myeloma	9.9%
235	Granulomatosis with polyangiitis	9.9%
236	Pituitary Apoplexy	9.9%
237	Supravalvular aortic stenosis	9.8%
238	Lown-Ganong-Levine Syndrome	9.8%
239	Cerebral Amyloid Angiopathy	9.7%
240	Lupus Vasculitis, Central Nervous System	9%
241	Ataxia Telangiectasia	9%
242	Pseudoxanthoma Elasticum	8.9%
243	Aortic Valve Insufficiency	8.9%
244	Restrictive cardiomyopathy	8.9%
245	Endocardial Fibroelastosis	8.9%
246	Heart Rupture, Post-Infarction	8.9%
247	Mitral Valve Insufficiency	8.9%
248	Mitral Valve Stenosis	8.9%
249	Myocarditis	8.9%
250	Pericarditis, Constrictive	8.9%
251	Pulmonary Valve Insufficiency	8.9%
252	Tricuspid Valve Insufficiency	8.9%
253	Tricuspid Valve Stenosis	8.9%
254	Ventricular Dysfunction, Left	8.9%
255	Right Ventricular Dysfunction	8.9%
256	Endomyocardial Fibrosis	8.9%
257	Carditis	8.9%
258	Heart Failure, Systolic	8.9%
259	Heart Failure, Diastolic	8.9%
260	Dextrocardia	8.8%
261	Long QT Syndrome	8.8%
262	Rheumatoid Vasculitis	8.5%
263	Sick Sinus Syndrome	8.4%
264	Adams-Stokes Syndrome	7.8%
265	Atrioventricular Block	7.8%
266	Bundle-Branch Block	7.8%
267	Atrial Premature Complexes	7.8%
268	Sinoatrial Block	7.8%
269	Tachycardia, Paroxysmal	7.8%
270	Supraventricular tachycardia	7.8%
271	Tachycardia, Ventricular	7.8%
272	Wolff-Parkinson-White Syndrome	7.8%
273	Tachycardia, Reciprocating	7.8%
274	Aortopulmonary Septal Defect	7.8%
275	Double Outlet Right Ventricle	7.8%
276	Endocardial Cushion Defects	7.8%
277	Myocardial bridging	7.8%
278	Aorticopulmonary Septal Defect	7.8%
279	Sinus Arrhythmia	6.7%
280	Atrial Fibrillation	6.7%
281	Atrial Flutter	6.7%
282	Edema, Cardiac	6.7%
283	Noonan Syndrome	6.7%
284	Ventricular Fibrillation	6.7%
285	Ventricular Flutter	6.7%
286	Parasystole	6.7%
287	Paroxysmal atrial fibrillation	6.7%
288	Bradycardia	6.7%
289	Diabetic Cardiomyopathies	6.7%
290	Cardiomyopathy, Alcoholic	6.6%
291	Ectopia Cordis	6.6%
292	Sudden Cardiac Death	6.6%
293	Left Ventricular Hypertrophy	6.6%
294	Right Ventricular Hypertrophy	6.6%
295	Single umbilical artery	6.6%
296	Aortic Valve Prolapse	6.6%
297	Tricuspid Valve Prolapse	6.6%
298	Takotsubo Cardiomyopathy	6.6%
299	Chagas Cardiomyopathy	6.6%
300	Subacute Bacterial Endocarditis	6.6%
301	Carcinoid Heart Disease	6.5%
302	Romano-Ward Syndrome	6.5%
303	Tachycardia, Atrioventricular Nodal Reentry	6.5%
304	Tachycardia, Ectopic Atrial	6.5%
305	Tachycardia, Ectopic Junctional	6.5%
306	Sinus Tachycardia	6.5%
307	Torsades de Pointes	6.5%
308	Accelerated Idioventricular Rhythm	6.5%
309	Truncus Arteriosus, Persistent	6.5%
310	Hematoma, Subdural	6.1%
311	Hematoma, Epidural, Cranial	6.1%
312	Marfan Syndrome	6%
313	Hematoma, Subdural, Intracranial	5.4%
314	Hematoma, Subdural, Chronic	5.4%
315	Hematoma, Subdural, Acute	5.4%
316	Brain Hemorrhage, Traumatic	5.4%
317	Dyspnea, Paroxysmal	5.3%
318	MELAS Syndrome	5.3%
319	Sinus Arrest, Cardiac	4.9%
320	Dural Arteriovenous Fistula	4.5%
321	Fabry Disease	4.1%
322	Turner Syndrome	3.4%
323	Kartagener Syndrome	2.9%
324	Williams Syndrome	2.7%
325	Kearns-Sayre syndrome	2.2%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234