MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neuritis, Autoimmune, Experimental

(UMLS:C0027814)

Definition:: An experimental animal model for the demyelinating disease of GUILLAINE-BARRE SYNDROME. In the most frequently used protocol, animals are injected with a peripheral nerve tissue protein homogenate. After approximately 2 weeks the animals develop a neuropathy secondary to a T cell-mediated autoimmune response directed towards the MYELIN P2 PROTEIN in peripheral nerves. Pathologic findings include a perivascular accumulation of macrophages and T lymphocytes in the peripheral nervous system, similar to that seen in the Guillaine-Barre syndrome. (From Adams et al., Principles of Neurology, 6th ed, p1314; J Neuroimmunol 1998 Apr 1;84(1):40-52)
UMLS ID:: C0027814
MeSH ID:: D009444

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.114.703.700|C10.668.829.650.500

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.111.258.625.700

Classification 3:

Name:

Investigative Techniques
MeSH Tree Number(s):: E05.598.500.500.875

Synonym(s)

Neuritis, Autoimmune, Experimental

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Nitric Oxide		9184692	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Myasthenia Gravis, Autoimmune, Experimental	42%
2	Stiff-Person Syndrome	30.1%
3	Polyradiculoneuropathy	30%
4	Polyradiculoneuritis	30%
5	Brachial Plexus Neuritis	27%
6	Neuralgic Amyotrophy	27%
7	Myasthenia Gravis	27%
8	Guillain-Barre Syndrome	26.9%
9	Lambert-Eaton Myasthenic Syndrome	21.2%
10	Uveomeningoencephalitic Syndrome	20.9%
11	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	20%
12	Complex Regional Pain Syndromes	19.9%
13	Causalgia	19.1%
14	Leukoencephalitis, Acute Hemorrhagic	18.9%
15	Neuromyelitis Optica	18.3%
16	Miller Fisher Syndrome	18.1%
17	Vasculitis, Central Nervous System	18%
18	Motor Neuron Disease	17.9%
19	Peripheral Nerve Injuries	17.2%
20	Multiple Sclerosis	16.8%
21	Radiculitis	16.3%
22	Polyneuropathy	16.3%
23	Mononeuritis	16.3%
24	Mononeuropathies	16.3%
25	Brachial Plexus Neuropathies	16.3%
26	Radiculopathy	16.3%
27	Mononeuropathy Multiplex	16.3%
28	Nerve Root Compression	16.3%
29	Encephalomyelitis, Acute Disseminated	16.3%
30	Tarsal Tunnel Syndrome	16.2%
31	Cauda Equina Syndrome	16.2%
32	Myelitis, Transverse	14.4%
33	Acrodynia	13.9%
34	Carpal Tunnel Syndrome	13.9%
35	Neuromuscular Junction Diseases	13.9%
36	Sciatica	13.8%
37	Isaacs syndrome	13.8%
38	Diabetic Neuropathies	13.7%
39	Diabetic Amyotrophy	13.7%
40	Diabetic Autonomic Neuropathy	13.7%
41	Neuralgia	13.6%
42	Neuropathic pain	13.6%
43	Reflex Sympathetic Dystrophy	13%
44	Lupus Vasculitis, Central Nervous System	13%
45	Cranial nerve diseases	12.9%
46	Demyelinating Diseases	12.9%
47	Demyelination	12.9%
48	Chronobiology Disorders	12.9%
49	Poliomyelitis	12.7%
50	Spinal Muscular Atrophy	12.7%
51	Progressive Muscular Atrophy	12.7%
52	Amyotrophic Lateral Sclerosis	12.4%
53	Multiple System Atrophy	12.4%
54	Multiple Sclerosis, Chronic Progressive	12.2%
55	Multiple Sclerosis, Relapsing-Remitting	12.2%
56	Hand-Arm Vibration Syndrome	12.2%
57	Chronic Fatigue Syndrome	12%
58	Myopathy	12%
59	Cubital Tunnel Syndrome	12%
60	Neoplasms, Experimental	11.9%
61	Restless Legs Syndrome	11.5%
62	Liver Cirrhosis, Experimental	11.5%
63	Arthritis, Experimental	11.5%
64	Trauma, Nervous System	11.1%
65	Sciatic Neuropathy	11%
66	Ulnar Neuropathies	11%
67	Lesion of Sciatic Nerve	11%
68	Ulnar Neuritis	11%
69	Radial nerve compression	11%
70	Radial Tunnel Syndrome	11%
71	Peroneal Neuropathies	11%
72	Radial Neuropathy	11%
73	Median Neuropathy	11%
74	Sciatic Nerve Palsy	11%
75	Femoral Neuropathy	11%
76	Tibial Neuropathy	11%
77	Ulnar Nerve Palsy	11%
78	Radial nerve palsy	11%
79	Progressive bulbar palsy	10.9%
80	Bulbar palsy	10.9%
81	Nervous System Neoplasms	10.9%
82	Neurologic Manifestations	10.9%
83	Neurotoxicity Syndromes	10.9%
84	Ocular Motility Disorders	10.8%
85	Cyclophoria	10.8%
86	Subacute Combined Degeneration	10.7%
87	Ophthalmoplegic Migraine	10.6%
88	Encephalomyelitis	9.9%
89	Prion Diseases	9.9%
90	Autonomic Dysreflexia	9.9%
91	Antiphospholipid Syndrome	9.9%
92	Botulism	9.9%
93	Diabetes Mellitus, Experimental	9.9%
94	Meningoencephalitis	9.8%
95	Giant Cell Arteritis	9.7%
96	Temporal Arteritis	9.7%
97	Sleep Wake Disorders	9.5%
98	Parkinson Disease	9.4%
99	Thoracic Outlet Syndrome	9.3%
100	Lewy Body Disease	9.1%
101	Charcot-Marie-Tooth Disease	9%
102	Marchiafava-Bignami Disease	8.8%
103	Spinal Cord Injuries	8.8%
104	Dandy-Walker Syndrome	8.6%
105	Pneumocephalus	8.6%
106	Progressive supranuclear palsy	8.6%
107	Asterixis	8.5%
108	Ballismus	8.5%
109	Striatonigral Degeneration	8.5%
110	Polyradiculopathy	8.4%
111	Lupus Erythematosus, Systemic	8.4%
112	Overlap syndrome	8.4%
113	neurofibroma	8.3%
114	Addison Disease	8.3%
115	Pemphigus	8.3%
116	Autoimmune thyroiditis	8.3%
117	Primary Adrenal Insufficiency	8.3%
118	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	8.2%
119	Autoimmune hepatitis	8.2%
120	POEMS Syndrome	8.2%
121	Opsoclonus-Myoclonus Syndrome	7.8%
122	Epidural Abscess	7.8%
123	Olfactory Nerve Injuries	7.8%
124	Sleep Disorders, Circadian Rhythm	7.7%
125	Myelitis	7.7%
126	Dyskinesia, Drug-Induced	7.6%
127	Radiation Injuries, Experimental	7.6%
128	Shy-Drager Syndrome	7.6%
129	MPTP Poisoning	7.6%
130	Neuroleptic Malignant Syndrome	7.5%
131	Myelinolysis, Central Pontine	7.5%
132	Autoimmune Lymphoproliferative Syndrome	7.5%
133	Central Nervous System Cysts	7.4%
134	Brain Diseases	7.3%
135	Dysautonomia	7.3%
136	Meningitis	7.3%
137	Movement Disorders	7.3%
138	Pachymeningitis	7.3%
139	Spinal Cord Diseases	7.3%
140	Vagus Nerve Disorder	7.3%
141	Glossopharyngeal Neuralgia	7.3%
142	Abducens Nerve Diseases	7.3%
143	Heavy Metal Poisoning, Nervous System	7.3%
144	Tauopathies	7.3%
145	Trochlear Nerve Diseases	7.3%
146	Myositis	7.2%
147	Myotonic Disorders	7.2%
148	Myasthenic Syndromes, Congenital	7.2%
149	Latent Autoimmune Diabetes in Adults	7.1%
150	Dermatitis Herpetiformis	7.1%
151	Amyloid Neuropathies, Familial	7.1%
152	Leukoencephalopathy, Progressive Multifocal	7%
153	Ataxia Telangiectasia	7%
154	Dystonia Musculorum Deformans	6.9%
155	Facial Nerve Injuries	6.9%
156	Myotonic Dystrophy	6.8%
157	Neuromuscular Diseases	6.8%
158	Akathisia, Drug-Induced	6.7%
159	Leukemia, Experimental	6.6%
160	Mammary Neoplasms, Experimental	6.6%
161	Sarcoma, Experimental	6.6%
162	Brain Injuries	6.6%
163	Horner Syndrome	6.6%
164	Myotonia Congenita	6.6%
165	Brain Neoplasms	6.5%
166	Spinal Cord Neoplasms	6.5%
167	Subdural Effusion	6.5%
168	Parkinsonian Disorders	6.5%
169	Nocturnal Myoclonus Syndrome	6.5%
170	Central Nervous System Infection	6.3%
171	Optic Neuropathy	6.3%
172	Rheumatoid Arthritis	6.3%
173	Juvenile arthritis	6.3%
174	Alstrom Syndrome	6.3%
175	Refsum Disease	6.2%
176	Huntington Disease	6.2%
177	Graves Disease	6.2%
178	Fibromyalgia	6.2%
179	Medial Tibial Stress Syndrome	6.2%
180	Mitochondrial Myopathies	6.2%
181	Limbic Encephalitis	6.2%
182	Facial Nerve Diseases	6.1%
183	Craniocerebral Trauma	6.1%
184	Parasomnia	6.1%
185	Dyssomnias	6.1%
186	Anti-Glomerular Basement Membrane Disease	6.1%
187	Eosinophilia-Myalgia Syndrome	6.1%
188	Hypersensitivity	6.1%
189	Immunologic Deficiency Syndromes	6.1%
190	Immunoproliferative Disorders	6.1%
191	Device Failure	6.1%
192	Immune reconstitution syndrome	6.1%
193	Immune Reconstitution Inflammatory Syndrome	6.1%
194	Vestibulocochlear Nerve Diseases	6.1%
195	Decerebrate State	6.1%
196	Hemiparesis	6.1%
197	Hydranencephaly	6.1%
198	Meningism	6.1%
199	Neural Tube Defects	6.1%
200	Paresis	6.1%
201	Seizures	6.1%
202	Sensation Disorders	6.1%
203	Tethered Cord Syndrome	6.1%
204	Central Nervous System Neoplasms	6.1%
205	Complex partial seizures	6.1%
206	Iniencephaly	6.1%
207	Craniorachischisis	6.1%
208	Exencephaly	6.1%
209	Monoparesis	6.1%
210	Septo-Optic Dysplasia	6.1%
211	Cortical Dysplasia	6.1%
212	Neurogenic Inflammation	6.1%
213	Gait Disorders, Neurologic	6.1%
214	Neuromuscular Manifestations	6.1%
215	Malformations of Cortical Development	6.1%
216	Epilepsy, Post-Traumatic	6.1%
217	Sweating, Gustatory	6%
218	Auriculotemporal Syndrome	6%
219	Autoimmune thrombocytopenia	6%
220	Immune thrombocytopenic purpura	6%
221	Tuberous Sclerosis	5.9%
222	Jet Lag Syndrome	5.9%
223	Canavan Disease	5.8%
224	Alexander Disease	5.8%
225	Brain Abscess	5.8%
226	Ophthalmoplegia	5.8%
227	External Ophthalmoplegia	5.8%
228	Scrapie	5.7%
229	Central Cord Syndrome	5.7%
230	Presenile dementia	5.6%
231	Senile dementia	5.6%
232	Meningitis, Bacterial	5.6%
233	Meningitis, Fungal	5.6%
234	Electrophoresis	5.6%
235	Chorea	5.6%
236	Lafora Disease	5.5%
237	Unverricht-Lundborg Syndrome	5.5%
238	Dementia, Vascular	5.4%
239	Brain Hemorrhage, Traumatic	5.4%
240	Cytogenetic Analysis	5.4%
241	Meige Syndrome	5.4%
242	Cerebral Ventriculitis	5.4%
243	Pupil Disorders	5.4%
244	Neurobehavioral Manifestations	5.4%
245	Familial Periodic Paralysis	5.3%
246	Neurofibrosarcoma	5.3%
247	Intubation	5.3%
248	Paraneoplastic Encephalomyelitis	5.3%
249	Cerebellar Neoplasms	5.2%
250	Sturge-Weber Syndrome	5.2%
251	Vertigo	5.2%
252	Alcohol-Induced Disorders, Nervous System	5.2%
253	Vocal Cord Paralysis	5.2%
254	Transfusion Reaction	5.1%
255	Hypotensive Transfusion Reaction	5.1%
256	Liver Neoplasms, Experimental	5.1%
257	Mitochondrial Encephalomyopathies	5.1%
258	Melanoma, Experimental	5.1%
259	Friedreich Ataxia	5%
260	Hepatolenticular Degeneration	5%
261	Amblyopia	4.9%
262	Paraneoplastic Cerebellar Degeneration	4.9%
263	Polymyositis	4.9%
264	Brain Death	4.9%
265	Coma, Post-Head Injury	4.9%
266	Cerebrospinal Fluid Otorrhea	4.9%
267	Cerebrospinal Fluid Rhinorrhea	4.9%
268	Carotid Artery Injuries	4.9%
269	Gait Ataxia	4.9%
270	Posterior Leukoencephalopathy Syndrome	4.9%
271	Posterior reversible encephalopathy syndrome	4.9%
272	Myalgia	4.7%
273	Creutzfeldt-Jakob disease	4.7%
274	Basal Ganglia Cerebrovascular Disease	4.7%
275	Tuberculosis, Meningeal	4.6%
276	Voice Disorders	4.6%
277	Voice Disturbance	4.6%
278	Brain Injuries, Diffuse	4.6%
279	Traumatic Brain Injury	4.6%
280	Cerebellar Ataxia	4.6%
281	Supratentorial Neoplasms	4.6%
282	Torticollis	4.6%
283	Akinetic Mutism	4.6%
284	Anoxic Encephalopathy	4.6%
285	Arachnoiditis	4.6%
286	Basal Ganglia Diseases	4.6%
287	Brain Damage, Chronic	4.6%
288	Cerebellar Diseases	4.6%
289	Encephalitis	4.6%
290	Encephalomalacia	4.6%
291	Epilepsy	4.6%
292	Hydrocephalus	4.6%
293	Congenital Hydrocephalus	4.6%
294	Hypothalamic Diseases	4.6%
295	Aseptic Meningitis	4.6%
296	Syringomyelia	4.6%
297	Thalamic Diseases	4.6%
298	Intracranial Hypertension	4.6%
299	Aura	4.6%
300	Leukoencephalopathy	4.6%
301	Essential Tremor	4.6%
302	Neuroaxonal Dystrophies	4.6%
303	Familial Tremor	4.6%
304	Headache Disorders	4.6%
305	Intracranial Hypotension	4.6%
306	Brain Edema	4.6%
307	Brain Hypoxia	4.6%
308	Aqueductal Stenosis	4.6%
309	Pneumorrhachis	4.6%
310	Writer's Cramp	4.6%
311	Alcohol Withdrawal Seizures	4.6%
312	Smith-Magenis syndrome	4.6%
313	Dural Arteriovenous Fistula	4.5%
314	Autopsy	4.4%
315	Optic Nerve Glioma	4.4%
316	Alice in Wonderland Syndrome	4.4%
317	Microscopy	4.3%
318	Akathisia	4.3%
319	Restlessness	4.3%
320	Psychomotor Agitation	4.3%
321	Myoclonic Epilepsy	4.3%
322	Epilepsy, Temporal Lobe	4.3%
323	Epilepsy, Rolandic	4.3%
324	Benign Rolandic Epilepsy	4.3%
325	Glomerulonephritis, Membranoproliferative	4.3%
326	Muscular Dystrophy	4.2%
327	Orbital Myositis	4.2%
328	Pyomyositis	4.2%
329	Brain Concussion	4.2%
330	Granulomatosis with polyangiitis	4.2%
331	Vascular Headaches	4.2%
332	Hypoxia-Ischemia, Brain	4.2%
333	Tardive Dyskinesia	4.1%
334	Persistent Vegetative State	4.1%
335	Toxoplasmosis, Cerebral	4.1%
336	Pituitary Adenoma	4.1%
337	Pituitary Neoplasms	4.1%
338	Leukomalacia, Periventricular	4.1%
339	Reflex, Abnormal	4%
340	Hyporeflexia	4%
341	Hyperreflexia	4%
342	Vertebral Artery Dissection	4%
343	Peripheral Nervous System Diseases	4%
344	Amnesia, Transient Global	4%
345	Gait Apraxia	4%
346	Brain Diseases, Metabolic	3.9%
347	Cerebrovascular Disorders	3.9%
348	Optic Atrophy	3.9%
349	Optic Neuritis	3.9%
350	Papilledema	3.9%
351	Strabismus	3.9%
352	Tolosa-Hunt Syndrome	3.9%
353	Cerebrovascular Insufficiency	3.9%
354	Arsenic Poisoning	3.9%
355	Dementia	3.9%
356	Central Nervous System Fungal Infections	3.9%
357	Conus Medullaris Syndrome	3.9%
358	Spinal Cord Vascular Diseases	3.9%
359	Facial Injuries	3.8%
360	Facial Neuralgia	3.8%
361	Sleep Talking	3.8%
362	Manganese Poisoning	3.8%
363	Sleep Disorders, Intrinsic	3.8%
364	Orthostatic intolerance	3.8%
365	Anosmia	3.8%
366	Ataxia	3.8%
367	Athetosis	3.8%
368	Catalepsy	3.8%
369	Dystonia	3.8%
370	Hemiplegia	3.8%
371	Locked-In Syndrome	3.8%
372	Meningeal Neoplasms	3.8%
373	Meningomyelocele	3.8%
374	Muscle Hypertonia	3.8%
375	Muscle hypotonia	3.8%
376	Myoclonus	3.8%
377	Myotonia	3.8%
378	Paraplegia	3.8%
379	Pseudobulbar Palsy	3.8%
380	Quadriplegia	3.8%
381	Spasm	3.8%
382	Spastic Paraplegia	3.8%
383	Status Epilepticus	3.8%
384	Taste Disorders	3.8%
385	Tremor	3.8%
386	Spina Bifida	3.8%
387	Monoplegia	3.8%
388	Hypokinesia	3.8%
389	Paraparesis	3.8%
390	Bradykinesia	3.8%
391	Waxy flexibility	3.8%
392	Action Tremor	3.8%
393	Resting Tremor	3.8%
394	Dysosmia	3.8%
395	Quadriparesis	3.8%
396	Mercury Poisoning, Nervous System	3.8%
397	Olfaction Disorders	3.8%
398	Myokymia	3.8%
399	Lead Poisoning, Nervous System	3.8%
400	Vestibular Neuronitis	3.8%
401	Somatosensory Disorders	3.8%
402	Hyperkinesia	3.8%
403	Intention tremor	3.8%
404	Juvenile Myoclonic Epilepsy	3.8%
405	Myoclonic Epilepsies, Progressive	3.8%
406	MELAS Syndrome	3.7%
407	Basal Ganglia Hemorrhage	3.7%
408	Diffuse Axonal Injury	3.7%
409	Brain Stem Neoplasms	3.7%
410	Felty Syndrome	3.7%
411	Lupus Nephritis	3.7%
412	Meningitis, Cryptococcal	3.7%
413	Hypokalemic periodic paralysis	3.6%
414	Meningitis, Listeria	3.6%
415	Meningitis, Haemophilus	3.6%
416	Meningitis, Pneumococcal	3.6%
417	Frontotemporal dementia	3.6%
418	Adrenoleukodystrophy	3.6%
419	Subarachnoid Hemorrhage, Traumatic	3.5%
420	Carotid Artery, Internal, Dissection	3.5%
421	Acoustic Neuroma	3.5%
422	Kearns-Sayre syndrome	3.5%
423	Subacute Sclerosing Panencephalitis	3.4%
424	Vision Disorders	3.4%
425	Metamorphopsia	3.4%
426	Visual Impairment	3.4%
427	Optic Neuropathy, Ischemic	3.3%
428	Anterior Ischemic Optic Neuropathy	3.3%
429	Central Nervous System Bacterial Infections	3.3%
430	Facial Hemiatrophy	3.3%
431	Melkersson-Rosenthal Syndrome	3.3%
432	Thrombocytopenic purpura	3.3%
433	Gastric Lavage	3.3%
434	Immune Complex Diseases	3.3%
435	Kernicterus	3.3%
436	Peritoneal lavage	3.3%
437	Latex allergy	3.3%
438	Bronchoalveolar Lavage	3.3%
439	Anisocoria	3.3%
440	Confusion	3.3%
441	Facial paralysis	3.3%
442	Lethargy	3.3%
443	Memory Disorders	3.3%
444	Muscle Cramp	3.3%
445	Perceptual Disorders	3.3%
446	Psychomotor Disorders	3.3%
447	Tonic Pupil	3.3%
448	Anhedonia	3.3%
449	Disorientation	3.3%
450	Facial Paresis	3.3%
451	Memory Loss	3.3%
452	Hemisensory Neglect	3.3%
453	Dysacusis	3.3%
454	Sleep Bruxism	3.3%
455	Anencephaly	3.3%
456	Meningocele	3.3%
457	Muscular Atrophy	3.3%
458	Respiratory Paralysis	3.3%
459	Encephalocele	3.3%
460	Putaminal Hemorrhage	3.3%
461	Pituitary Apoplexy	3.3%
462	Rheumatoid Vasculitis	3.3%
463	Tetany	3.3%
464	Auditory Perceptual Disorders	3.3%
465	Welander Distal Myopathy	3.2%
466	Cerebral Palsy	3.2%
467	Epilepsies, Partial	3.2%
468	Epilepsy, Generalized	3.2%
469	Pseudotumor Cerebri	3.2%
470	Hypertensive Encephalopathy	3.2%
471	Simple Partial Seizures	3.2%
472	Epilepsy, Reflex	3.2%
473	Postural Orthostatic Tachycardia Syndrome	3.2%
474	Headache Disorders, Primary	3.2%
475	Headache Disorders, Secondary	3.2%
476	Medication overuse headache	3.2%
477	Brain Contusion	3.2%
478	Brain Infarction	3.2%
479	Classical Lissencephalies and Subcortical Band Heterotopias	3.2%
480	Choroid Plexus Papilloma	3.2%
481	Infarction, Middle Cerebral Artery	3.2%
482	Infarction, Anterior Cerebral Artery	3.2%
483	Infarction, Posterior Cerebral Artery	3.2%
484	Sicca Syndrome	2.9%
485	Sjogren's Syndrome	2.9%
486	Duane Retraction Syndrome	2.9%
487	Consciousness Disorders	2.9%
488	Mental Retardation	2.9%
489	Muscle Weakness	2.9%
490	Depressed Level of Consciousness	2.9%
491	Mental deficiency	2.9%
492	Intellectual Disability	2.9%
493	Mobius Syndrome	2.9%
494	Bell Palsy	2.9%
495	Dermatomyositis	2.9%
496	AIDS Dementia Complex	2.9%
497	Catatonia	2.9%
498	Herpes Zoster Oticus	2.9%
499	Aphonia	2.9%
500	Sleep Deprivation	2.9%
501	Dysphonia	2.9%
502	Alexia	2.9%
503	Dyslexia	2.9%
504	Environmental Illness	2.9%
505	Muscular Dystrophy, Duchenne	2.9%
506	Pituitary Diseases	2.8%
507	Cerebral Infarction	2.8%
508	Brain Stem Infarctions	2.8%
509	Lymphoproliferative Disorders	2.8%
510	West Nile Fever	2.8%
511	Paraproteinemias	2.8%
512	Prosthesis Failure	2.8%
513	Lymphopenia	2.7%
514	Immunosuppression	2.7%
515	Hematoma, Subdural	2.7%
516	Hematoma, Epidural, Cranial	2.7%
517	Carotid Artery Diseases	2.7%
518	Brain Ischemia	2.7%
519	Esotropia	2.7%
520	Exotropia	2.7%
521	Hypotension, Orthostatic	2.7%
522	Sleep Apnea Syndromes	2.7%
523	Cerebrovascular accident	2.7%
524	Kluver-Bucy Syndrome	2.7%
525	Vasospasm, Intracranial	2.7%
526	Spinal Cord Ischemia	2.7%
527	Intracranial Arterial Diseases	2.7%
528	Post-Exercise Hypotension	2.7%
529	Disorders of Excessive Somnolence	2.7%
530	Sleep Initiation and Maintenance Disorders	2.7%
531	Night Terrors	2.7%
532	Somnambulism	2.7%
533	Trigeminal Nerve Disorder	2.7%
534	Transient Insomnia	2.7%
535	Sleep Paralysis	2.7%
536	Chronic Insomnia	2.7%
537	REM Sleep Behavior Disorder	2.7%
538	Hypersomnia	2.7%
539	Dermal Sinus	2.7%
540	Dysgeusia	2.7%
541	Formication	2.7%
542	Hyperalgesia	2.7%
543	Hyperesthesia	2.7%
544	Hypesthesia	2.7%
545	Language Disorders	2.7%
546	Numbness	2.7%
547	Paresthesia	2.7%
548	Paraparesis, Spastic	2.7%
549	Spina Bifida Cystica	2.7%
550	Trismus	2.7%
551	Spina Bifida Occulta	2.7%
552	Epilepsia Partialis Continua	2.7%
553	Hypogeusia	2.7%
554	Meningeal Carcinomatosis	2.7%
555	Brown-Sequard Syndrome	2.7%
556	Lissencephaly	2.7%
557	Polymicrogyria	2.7%
558	Pachygyria	2.7%
559	Schizencephaly	2.7%
560	Lockjaw	2.7%
561	Allodynia	2.7%
562	Lead Poisoning, Nervous System, Childhood	2.7%
563	Lead Poisoning, Nervous System, Adult	2.7%
564	Periventricular Nodular Heterotopia	2.7%
565	Ageusia	2.7%
566	Tuberculosis, Central Nervous System	2.7%
567	Moyamoya Disease	2.7%
568	Optic Atrophy, Hereditary, Leber	2.7%
569	Neuritis	2.6%
570	Polyneuritis	2.6%
571	Lateral Medullary Syndrome	2.6%
572	Post-Traumatic Headache	2.6%
573	Tension Headache	2.6%
574	Epilepsy, Complex Partial	2.6%
575	Migraine Disorders	2.6%
576	Abdominal Migraine	2.6%
577	Status Migrainosus	2.6%
578	Cervicogenic Headache	2.6%
579	Glasgow coma scale	2.5%
580	Neuronal Ceroid-Lipofuscinoses	2.5%
581	Primary amyloidosis	2.5%
582	Monoclonal Gammopathy of Undetermined Significance	2.4%
583	Neuritis, Autoimmune, Experimental	2.4%
584	Biopsy	2.4%
585	Eye Injuries	2.4%
586	Hypergammaglobulinemia	2.4%
587	Agammaglobulinemia	2.4%
588	Kounis Syndrome	2.4%
589	HIV Infections	2.4%
590	Congenital nystagmus	2.4%
591	Transfusion-Related Acute Lung Injury	2.4%
592	Diplopia	2.3%
593	Muscle Rigidity	2.3%
594	Muscle Spasticity	2.3%
595	Scotoma	2.3%
596	Photophobia	2.3%
597	Cogwheel Rigidity	2.3%
598	Hemifacial Spasm	2.3%
599	Amaurosis	2.3%
600	Blindness	2.3%
601	Nuchal Rigidity	2.3%
602	Reye Syndrome	2.3%
603	Neuroaspergillosis	2.3%
604	Aicardi's syndrome	2.3%
605	Intracranial Embolism and Thrombosis	2.3%
606	Hepatic Encephalopathy	2.3%
607	Agnosia	2.3%
608	Apraxias	2.3%
609	Hallucinations	2.3%
610	Hemianopsia	2.3%
611	Hyperacusis	2.3%
612	Tinnitus	2.3%
613	Visual Agnosia	2.3%
614	Anosognosia	2.3%
615	Wernicke-Korsakoff Syndrome	2.3%
616	Phonophobia	2.3%
617	Hearing Loss	2.3%
618	Hematoma, Subdural, Intracranial	2.3%
619	Hematoma, Subdural, Chronic	2.3%
620	Hematoma, Subdural, Acute	2.3%
621	Hoarseness	2.3%
622	Sarcopenia	2.3%
623	Cockayne Syndrome	2.3%
624	Alcohol Withdrawal Delirium	2.3%
625	Cluster Headache	2.3%
626	Migraine with Aura	2.3%
627	Familial Hemiplegic Migraine	2.3%
628	Chronic Paroxysmal Hemicrania	2.3%
629	SUNCT Syndrome	2.3%
630	Paroxysmal Hemicrania	2.3%
631	Asthma, Aspirin-Induced	2.2%
632	Empty Sella Syndrome	2.2%
633	Hyperpituitarism	2.2%
634	Hypopituitarism	2.2%
635	Hypophysitis	2.2%
636	Cerebral Arterial Diseases	2.2%
637	Vertebrobasilar Insufficiency	2.2%
638	Anterior Spinal Artery Syndrome	2.2%
639	Basilar Artery Stenosis	2.2%
640	Vertebral Artery Stenosis	2.2%
641	Sleep Apnea, Obstructive	2.2%
642	Sleep Apnea, Central	2.2%
643	Intracranial Hemorrhage, Hypertensive	2.2%
644	Transient Cerebral Ischemia	2.2%
645	Narcolepsy	2.2%
646	Trigeminal Neuralgia	2.2%
647	Kleine-Levin Syndrome	2.2%
648	Agraphia	2.1%
649	Anomia	2.1%
650	Cluttering	2.1%
651	Language Development Disorders	2.1%
652	Speech Disorders	2.1%
653	Syncope	2.1%
654	Stupor	2.1%
655	Dysgraphia	2.1%
656	Presyncope	2.1%
657	Dyslalia	2.1%
658	Pseudorabies	2.1%
659	Holoprosencephaly	2.1%
660	Angioplasty	2.1%
661	Amniocentesis	2.1%
662	Amnesia	2.1%
663	Delirium	2.1%
664	Dissociative Amnesia	2.1%
665	Color blindness	2.1%
666	Global Amnesia	2.1%
667	Cri-du-Chat Syndrome	2%
668	Down Syndrome	2%
669	Brain Diseases, Metabolic, Inborn	2%
670	Trisomy 21	2%
671	Meningioma	2%
672	Williams Syndrome	2%
673	Serum Sickness	2%
674	Microcephaly	2%
675	Macrocephaly	2%
676	Neurosyphilis	2%
677	Porencephaly	2%
678	Multiple Myeloma	2%
679	anaphylaxis	2%
680	Food Allergy	2%
681	Polymerase Chain Reaction	2%
682	Anaphylactic shock	2%
683	Hyperprolactinemia	1.9%
684	Subclavian Steal Syndrome	1.9%
685	Pick Disease of the Brain	1.9%
686	Cataplexy	1.9%
687	Aphasia	1.9%
688	Articulation Disorders	1.9%
689	Echolalia	1.9%
690	Stuttering	1.9%
691	Dysphasia	1.9%
692	Toxoplasmosis, Congenital	1.9%
693	Eye Burns	1.9%
694	Malaria, Cerebral	1.9%
695	Waterhouse-Friderichsen Syndrome	1.9%
696	Carotid Stenosis	1.9%
697	Intracranial Aneurysm	1.9%
698	Neurocysticercosis	1.9%
699	Amaurosis Fugax	1.8%
700	Blindness, Cortical	1.8%
701	Dyscalculia	1.8%
702	Intracranial Arteriosclerosis	1.8%
703	Cerebral Atherosclerosis	1.8%
704	Menkes Kinky Hair Syndrome	1.8%
705	Rett Syndrome	1.8%
706	Subarachnoid Hemorrhage	1.8%
707	Tuberculin Test	1.8%
708	Cerebral Arteriosclerosis	1.8%
709	Cerebral Hemorrhage	1.8%
710	Cerebral Thrombosis	1.8%
711	Intracranial Embolism	1.8%
712	Intracranial Thrombosis	1.8%
713	Deafness	1.8%
714	Hearing Loss, Sudden	1.8%
715	Gerstmann Syndrome	1.8%
716	Hearing Loss, Bilateral	1.8%
717	Hearing Loss, High-Frequency	1.8%
718	Hearing Loss, Mixed Conductive-Sensorineural	1.8%
719	Prosopagnosia	1.8%
720	Apraxia, Ideomotor	1.8%
721	Charles Bonnet Syndrome	1.8%
722	Hearing Loss, Unilateral	1.8%
723	Complete Hearing Loss	1.8%
724	Alien Hand Syndrome	1.8%
725	Deaf Mutism	1.8%
726	Prader-Willi Syndrome	1.8%
727	Wernicke Encephalopathy	1.8%
728	Phantom pain	1.8%
729	Phantom Limb Pain	1.8%
730	Lyme Neuroborreliosis	1.8%
731	Dysarthria	1.7%
732	Respiratory Hypersensitivity	1.7%
733	Sick Building Syndrome	1.7%
734	Multiple Chemical Sensitivity	1.7%
735	Corneal Scar	1.7%
736	Ovulation Induction	1.6%
737	Plasmacytoma	1.6%
738	Tumor Lysis Syndrome	1.6%
739	Urticaria	1.6%
740	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
741	Mutism	1.6%
742	Selective Mutism	1.6%
743	HTLV-I Infections	1.6%
744	Blood culture	1.6%
745	Job Syndrome	1.6%
746	Acromegaly	1.6%
747	Immunoglobulin Therapy	1.6%
748	Retrograde amnesia	1.6%
749	Amnesia, Anterograde	1.6%
750	Carotid Artery Thrombosis	1.6%
751	Cerebral Amyloid Angiopathy	1.6%
752	Sinus Thrombosis, Intracranial	1.6%
753	Alexia, Pure	1.5%
754	Hydrops Fetalis	1.5%
755	Rubinstein-Taybi Syndrome	1.5%
756	Cavernous Sinus Thrombosis	1.5%
757	Sagittal Sinus Thrombosis	1.5%
758	Sezary Syndrome	1.5%
759	Fabry Disease	1.4%
760	Fragile X Syndrome	1.4%
761	Lymphoma	1.4%
762	Corneal Perforation	1.4%
763	Mastocytosis	1.4%
764	Drug Eruptions	1.4%
765	Chronic granulomatous disease	1.4%
766	Heavy Chain Disease	1.4%
767	Dermatitis, Allergic Contact	1.4%
768	HIV Seropositivity	1.4%
769	Nelson Syndrome	1.3%
770	Milk Allergy	1.3%
771	Schnitzler Syndrome	1.3%
772	Wheat Hypersensitivity	1.3%
773	Galactosemias	1.3%
774	Urea Cycle Disorders, Inborn	1.3%
775	Tyrosinemias	1.3%
776	Leukapheresis	1.3%
777	Prolactinoma	1.3%
778	Growth Hormone-Secreting Pituitary Adenoma	1.3%
779	Acquired Immunodeficiency Syndrome	1.2%
780	AIDS related complex	1.2%
781	Infectious Mononucleosis	1.2%
782	Cryoglobulinemia	1.2%
783	Atherectomy	1.2%
784	Body mass index	1.2%
785	Homocystinuria	1.2%
786	Leigh Disease	1.2%
787	AIDS-Related Opportunistic Infections	1.1%
788	Dermatitis, Atopic	1.1%
789	HIV Wasting Syndrome	1.1%
790	AIDS-Associated Nephropathy	1.1%
791	Mastocytosis, Systemic	1.1%
792	Mucopolysaccharidosis II	1.1%
793	Carbamoyl-Phosphate Synthase I Deficiency Disease	1%
794	Paracentesis	1%
795	Waldenstrom Macroglobulinemia	1%
796	Wiskott-Aldrich Syndrome	1%
797	HIV-Associated Lipodystrophy Syndrome	1%
798	Angioedema	0.9%
799	PROTHROMBIN TIME	0.9%
800	Zellweger Syndrome	0.9%
801	Glycogen storage disease type II	0.9%
802	Hodgkin Disease	0.9%
803	Leukemia, Plasma Cell	0.9%
804	Lymphoma, Non-Hodgkin	0.9%
805	Glucose tolerance test	0.9%
806	Leukemia, T-Cell	0.9%
807	Superovulation	0.9%
808	Acute Generalized Exanthematous Pustulosis	0.9%
809	Leukemia, B-Cell	0.9%
810	Clot retraction	0.9%
811	Asthma	0.8%
812	venipuncture	0.8%
813	Composite Lymphoma	0.8%
814	Erythema Nodosum	0.8%
815	Dermatitis, Photoallergic	0.8%
816	Lymphangioleiomyomatosis	0.8%
817	Body Height	0.8%
818	Gaucher Disease	0.8%
819	Tay-Sachs Disease	0.7%
820	Aspergillosis, Allergic Bronchopulmonary	0.7%
821	Body Weight	0.7%
822	Niemann-Pick Disease, Type C	0.7%
823	Asthma, Exercise-Induced	0.7%
824	Status Asthmaticus	0.7%
825	Lymphoma, Follicular	0.7%
826	T-Cell Lymphoma	0.7%
827	Mantle cell lymphoma	0.7%
828	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.7%
829	Leukemia, Large Granular Lymphocytic	0.7%
830	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.7%
831	Toxic Epidermal Necrolysis	0.6%
832	Stevens-Johnson Syndrome	0.6%
833	Asthma, Occupational	0.6%
834	Farmer's Lung	0.6%
835	Angioedemas, Hereditary	0.6%
836	Hay fever	0.6%
837	Rhinitis, Allergic, Perennial	0.6%
838	Hereditary Angioedema Type III	0.6%
839	Hereditary Angioedema Types I and II	0.6%
840	Lymphoma, T-Cell, Cutaneous	0.6%
841	Lymphoma, AIDS-Related	0.6%
842	Enteropathy-Associated T-Cell Lymphoma	0.6%
843	Primary Effusion Lymphoma	0.6%
844	Birth Weight	0.5%
845	Mycosis Fungoides	0.5%
846	Lymphomatoid Papulosis	0.5%
847	Plasmablastic lymphoma	0.5%
848	Lymphomatoid Granulomatosis	0.5%
849	Burkitt Lymphoma	0.4%
850	Fetal Weight	0.4%

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