MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Moyamoya Disease

(UMLS:C0026654)

Definition:: A noninflammatory, progressive occlusion of the intracranial CAROTID ARTERIES and the formation of netlike collateral arteries arising from the CIRCLE OF WILLIS. Cerebral angiogram shows the puff-of-smoke (moyamoya) collaterals at the base of the brain. It is characterized by endothelial HYPERPLASIA and FIBROSIS with thickening of arterial walls. This disease primarily affects children but can also occur in adults.
UMLS ID:: C0026654
MeSH ID:: D009072

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.200.600|C10.228.140.300.510.200.737

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.137.615|C14.907.253.123.620|C14.907.253.560.200.737

Synonym(s)

Moyamoya Disease

MOYAMOYA

MOYAMOYA DISEASE

Moyamoya disease

Progressive intracranial arterial occlusion

Progressive intracranial arterial occlusion syndrome

disease (or disorder); moyamoya

disease moya moya

disease moyamoya

10.

moya disease

11.

moya moya disease

12.

moya-moya disease

13.

moyamoya

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Deferasirox	FAERS: 11		OFFSIDES US FAERS
2	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 4		US FAERS
3	Sitagliptin Phosphate	FAERS: 2		US FAERS
4	Zoledronic Acid	FAERS: 2		US FAERS
5	Acetaminophen	FAERS: 1		US FAERS
6	Aspirin	FAERS: 1	16551458	CTD US FAERS
7	Carbamazepine	FAERS: 1		US FAERS
8	Estrogens, Conjugated (USP)	FAERS: 1		US FAERS
9	Insulin Detemir	FAERS: 1		US FAERS
10	Minoxidil	FAERS: 1		US FAERS
11	Norethindrone acetate and ethinyl estradiol	FAERS: 1		US FAERS
12	Norgestrel	FAERS: 1		US FAERS
13	NuvaRing	FAERS: 1		US FAERS
14	Pentazocine	FAERS: 1		US FAERS
15	Pentazocine	FAERS: 1		US FAERS
16	Valsartan	FAERS: 1		US FAERS
17	fesoterodine	FAERS: 1		US FAERS
18	rofecoxib	FAERS: 1		US FAERS
19	Cocaine		10871003 11110558	CTD
20	Dexmedetomidine			OFFSIDES
21	Dipyridamole		16551458	CTD
22	Enalapril		9143594	CTD
23	Ergotamine		16871899	CTD
24	Furosemide		9143594	CTD
25	polaprezinc			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Carotid Stenosis	54.9%
2	Carotid Artery Thrombosis	50%
3	Infarction, Middle Cerebral Artery	47.1%
4	Infarction, Anterior Cerebral Artery	47.1%
5	Infarction, Posterior Cerebral Artery	47.1%
6	Intracranial Arteriosclerosis	46.2%
7	Cerebral Atherosclerosis	46.2%
8	Cerebral Arteriosclerosis	46.2%
9	Carotid Artery Injuries	45.9%
10	Intracranial Aneurysm	45.2%
11	Intracranial Embolism and Thrombosis	44.9%
12	Basal Ganglia Cerebrovascular Disease	44.8%
13	Dementia, Vascular	44%
14	Brain Infarction	42.6%
15	Brain Ischemia	42.3%
16	Cerebrovascular accident	42.3%
17	Vasospasm, Intracranial	42.3%
18	Vasculitis, Central Nervous System	42.3%
19	Vascular Headaches	41.9%
20	Leukomalacia, Periventricular	40%
21	Cerebral Amyloid Angiopathy	36.7%
22	Carotid Artery, Internal, Dissection	35.6%
23	Leriche Syndrome	33.8%
24	Thromboangiitis Obliterans	33.8%
25	Basal Ganglia Hemorrhage	33.6%
26	Subarachnoid Hemorrhage, Traumatic	33%
27	Hypoxia-Ischemia, Brain	31.7%
28	Cerebral Infarction	31%
29	Brain Stem Infarctions	31%
30	Cerebral Thrombosis	29.9%
31	Intracranial Embolism	29.9%
32	Intracranial Thrombosis	29.9%
33	Malignant Atrophic Papulosis	29.7%
34	Myocardial Ischemia	29.3%
35	Spinal Cord Vascular Diseases	28.4%
36	Giant Cell Arteritis	27.9%
37	Temporal Arteritis	27.9%
38	Vertebrobasilar Insufficiency	27.4%
39	Basilar Artery Stenosis	27.4%
40	Vertebral Artery Stenosis	27.4%
41	Intracranial Hemorrhage, Hypertensive	27.4%
42	Transient Cerebral Ischemia	27.4%
43	Vertebral Artery Dissection	27.2%
44	Aortic Aneurysm	26.4%
45	Aortitis	26.4%
46	Periphlebitis	26.4%
47	Phlebitis	26.4%
48	Pituitary Apoplexy	25.9%
49	Intracranial Arterial Diseases	25.6%
50	Putaminal Hemorrhage	25.5%
51	Aneurysm	25.3%
52	Angiomatosis	25.3%
53	Aortic Diseases	25.3%
54	Hyperemia	25.3%
55	Hypotension	25.3%
56	Superior Vena Cava Syndrome	25.3%
57	Telangiectasis	25.3%
58	Vasculitis	25.3%
59	Venous Insufficiency	25.3%
60	Peripheral Vascular Diseases	25.3%
61	Embolism and Thrombosis	25.3%
62	Angiodysplasia	25.3%
63	Capillary Leak Syndrome	25.3%
64	Prehypertension	25.3%
65	Retinal Vein Occlusion	25.3%
66	Lateral Medullary Syndrome	25.3%
67	Myocardial Reperfusion Injury	24.8%
68	Moyamoya Disease	24.6%
69	Subarachnoid Hemorrhage	24%
70	Cerebral Hemorrhage	24%
71	Arteriosclerosis	24%
72	Fibromuscular Dysplasia	24%
73	Pulmonary artery stenosis	24%
74	Lupus Vasculitis, Central Nervous System	23.8%
75	Coronary Artery Disease	23.1%
76	Shwartzman Phenomenon	23.1%
77	Thoracic Outlet Syndrome	22.9%
78	Sinus Thrombosis, Intracranial	22.5%
79	Vascular System Injuries	22.4%
80	Carotid Artery Diseases	22.3%
81	Postphlebitic Syndrome	22.1%
82	Coronary Aneurysm	22%
83	Compartment syndromes	22%
84	Hepatic Veno-Occlusive Disease	22%
85	Peliosis Hepatis	22%
86	Varicocele	22%
87	Diabetic Angiopathies	21.8%
88	Reperfusion Injury	21.8%
89	Splenic Infarction	21.8%
90	Vascular Neoplasms	21.8%
91	Vasoplegia	21.8%
92	Thrombophlebitis	21.7%
93	Hemorrhoids	21.7%
94	Hand-Arm Vibration Syndrome	21.6%
95	Optic Neuropathy, Ischemic	21.2%
96	Anterior Ischemic Optic Neuropathy	21.2%
97	Aortic Rupture	21.1%
98	Retinal Artery Occlusion	20.8%
99	Arteriovenous fistula	20.6%
100	Meningoencephalitis	20.2%
101	Subclavian Steal Syndrome	20%
102	Mesenteric vascular insufficiency	19.2%
103	Subdural Effusion	19.1%
104	Blue Toe Syndrome	19%
105	Encephalomyelitis	18.9%
106	Angioedema	18.9%
107	Colitis, Ischemic	18.9%
108	Cavernous Sinus Thrombosis	18.9%
109	Sagittal Sinus Thrombosis	18.9%
110	Brain Hemorrhage, Traumatic	18.3%
111	Coronary Thrombosis	18.3%
112	Shy-Drager Syndrome	18.3%
113	Mesenteric Vascular Occlusion	18.3%
114	Renal Artery Obstruction	18%
115	Renal Artery Stenosis	18%
116	Aortic Aneurysm, Abdominal	17.9%
117	Aortic Aneurysm, Thoracic	17.9%
118	Akinetic Mutism	17.9%
119	Anoxic Encephalopathy	17.9%
120	Basal Ganglia Diseases	17.9%
121	Brain Damage, Chronic	17.9%
122	Cerebellar Diseases	17.9%
123	Encephalitis	17.9%
124	Encephalomalacia	17.9%
125	Epilepsy	17.9%
126	Hydrocephalus	17.9%
127	Congenital Hydrocephalus	17.9%
128	Hypothalamic Diseases	17.9%
129	Thalamic Diseases	17.9%
130	Intracranial Hypertension	17.9%
131	Aura	17.9%
132	Leukoencephalopathy	17.9%
133	Neuroaxonal Dystrophies	17.9%
134	Headache Disorders	17.9%
135	Intracranial Hypotension	17.9%
136	Brain Edema	17.9%
137	Brain Hypoxia	17.9%
138	Aqueductal Stenosis	17.9%
139	Coronary heart disease	17.6%
140	Myocardial Infarction	17.6%
141	Acute Coronary Syndrome	17.6%
142	Pneumocephalus	17.4%
143	Cerebral Arterial Diseases	17.4%
144	Brain Abscess	17.3%
145	Dandy-Walker Syndrome	17.1%
146	Multiple System Atrophy	17.1%
147	Spinal Cord Ischemia	17%
148	Scimitar Syndrome	16.9%
149	MELAS Syndrome	16.9%
150	Arteriosclerosis Obliterans	16.9%
151	Atherosclerosis	16.9%
152	Lewy Body Disease	15.8%
153	Polyarteritis Nodosa	15.7%
154	Takayasu Arteritis	15.7%
155	Kounis Syndrome	15.6%
156	Brain Diseases, Metabolic	15.6%
157	Dementia	15.6%
158	Arterial Occlusive Diseases	15.5%
159	Brain Injuries	15.5%
160	Parkinsonian Disorders	15.5%
161	Brain Neoplasms	15.4%
162	May-Thurner Syndrome	15.4%
163	Angina Pectoris	15.4%
164	Aneurysm, Dissecting	15.3%
165	Arteritis	15.3%
166	Embolism	15.3%
167	Erythromelalgia	15.3%
168	Malignant Hypertension	15.3%
169	Raynaud Disease	15.3%
170	Thromboembolism	15.3%
171	Thrombosis	15.3%
172	Essential Hypertension	15.3%
173	Aneurysm, Ruptured	15.3%
174	Iliac Aneurysm	15.3%
175	White Coat Hypertension	15.3%
176	Systemic Vasculitis	15.3%
177	Embolus	15.3%
178	Heart Diseases	15.3%
179	Sturge-Weber Syndrome	15.2%
180	Ocular Motility Disorders	14.8%
181	Cyclophoria	14.8%
182	Epilepsy, Post-Traumatic	14.7%
183	Intermittent Claudication	14.7%
184	Posterior Leukoencephalopathy Syndrome	14.4%
185	Posterior reversible encephalopathy syndrome	14.4%
186	Hypotension, Orthostatic	14.4%
187	Post-Exercise Hypotension	14.4%
188	Embolism, Amniotic Fluid	14.3%
189	Meningitis	14.3%
190	Movement Disorders	14.3%
191	Pachymeningitis	14.3%
192	Spinal Cord Diseases	14.3%
193	CREST Syndrome	14.1%
194	Brain Death	13.9%
195	Hematoma, Subdural	13.6%
196	Hematoma, Epidural, Cranial	13.6%
197	Retinal Vasculitis	13.3%
198	Hypertensive Retinopathy	13.3%
199	Pregnancy Complications, Cardiovascular	13.2%
200	Cardiovascular Abnormalities	13.2%
201	Epidural Abscess	13.2%
202	Anterior Compartment Syndrome	13.2%
203	Myelitis	13.2%
204	Vasculitis, Leukocytoclastic, Cutaneous	13.2%
205	Gastric Antral Vascular Ectasia	13.2%
206	Abdominal Compartment Syndrome	13.2%
207	Varicose Ulcer	13.1%
208	Primary Graft Dysfunction	13.1%
209	Huntington Disease	13.1%
210	Marchiafava-Bignami Disease	13%
211	Amblyopia	13%
212	Ataxia Telangiectasia	13%
213	Lemierre Syndrome	12.6%
214	Central Nervous System Infection	12.6%
215	Meige Syndrome	12.6%
216	Cerebral Ventriculitis	12.6%
217	Fabry Disease	12.5%
218	Coronary Occlusion	11.9%
219	Microvascular Angina	11.9%
220	Coronary Stenosis	11.9%
221	ST segment elevation myocardial infarction	11.9%
222	Parkinson Disease	11.9%
223	Progressive supranuclear palsy	11.8%
224	Cerebellar Neoplasms	11.8%
225	Mucocutaneous Lymph Node Syndrome	11.7%
226	Stiff-Person Syndrome	11.7%
227	Diabetic Retinopathy	11.6%
228	Dystonia Musculorum Deformans	11.6%
229	Livedo Reticularis	11.6%
230	Renal hypertension	11.6%
231	Hemangioma, Cavernous	11.5%
232	Scurvy	11.5%
233	Neuroleptic Malignant Syndrome	11.4%
234	Myelinolysis, Central Pontine	11.4%
235	Anterior Spinal Artery Syndrome	11.3%
236	Amnesia, Transient Global	11.3%
237	Myoclonic Epilepsy	11.2%
238	Epilepsy, Temporal Lobe	11.2%
239	Epilepsy, Rolandic	11.2%
240	Benign Rolandic Epilepsy	11.2%
241	Leukoencephalopathy, Progressive Multifocal	11.1%
242	Creutzfeldt-Jakob disease	11.1%
243	Hematoma, Subdural, Intracranial	10.9%
244	Hematoma, Subdural, Chronic	10.9%
245	Hematoma, Subdural, Acute	10.9%
246	Prion Diseases	10.8%
247	Shock, Cardiogenic	10.5%
248	Subacute Combined Degeneration	10.5%
249	Limbic Encephalitis	10.4%
250	Air Embolism	10.4%
251	Endarteritis	10.4%
252	Venous Thrombosis	10.4%
253	Deep Vein Thrombosis	10.4%
254	Venous Thromboembolism	10.4%
255	Angina, Unstable	10.4%
256	Ischemic contracture	10.3%
257	Cerebral Palsy	10.3%
258	Epilepsies, Partial	10.3%
259	Epilepsy, Generalized	10.3%
260	Pseudotumor Cerebri	10.3%
261	Hypertensive Encephalopathy	10.3%
262	Simple Partial Seizures	10.3%
263	Epilepsy, Reflex	10.3%
264	Headache Disorders, Primary	10.3%
265	Headache Disorders, Secondary	10.3%
266	Medication overuse headache	10.3%
267	Angioedemas, Hereditary	10.3%
268	Tricuspid Atresia	10.3%
269	Arrhythmogenic Right Ventricular Dysplasia	10.3%
270	Hepatolenticular Degeneration	10.3%
271	Cryoglobulinemia	10.3%
272	Diabetic Foot	10.2%
273	Striatonigral Degeneration	10%
274	Presenile dementia	9.7%
275	Senile dementia	9.7%
276	Spinal Cord Injuries	9.7%
277	Spinal Muscular Atrophy	9.7%
278	Progressive Muscular Atrophy	9.7%
279	Asterixis	9.4%
280	Ballismus	9.4%
281	Cranial nerve diseases	9.3%
282	Demyelinating Diseases	9.3%
283	Demyelination	9.3%
284	Neuromuscular Diseases	9.3%
285	Chronobiology Disorders	9.3%
286	Amyotrophic Lateral Sclerosis	9.3%
287	Purpura, Hyperglobulinemic	9.2%
288	Bacterial Endocarditis	9.2%
289	Coronary Restenosis	9.1%
290	Pituitary Diseases	9.1%
291	Poliomyelitis	9.1%
292	Meningitis, Bacterial	9.1%
293	Meningitis, Fungal	9.1%
294	Pulmonary Embolism	9.1%
295	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	9.1%
296	No-Reflow Phenomenon	9%
297	Leukoencephalitis, Acute Hemorrhagic	8.9%
298	Kluver-Bucy Syndrome	8.9%
299	Brain Injuries, Diffuse	8.8%
300	Traumatic Brain Injury	8.8%
301	Cerebellar Ataxia	8.8%
302	Supratentorial Neoplasms	8.8%
303	Toxoplasmosis, Cerebral	8.8%
304	Aortic Valve Stenosis	8.8%
305	Cardiomyopathy, Dilated	8.8%
306	Pulmonary Valve Stenosis	8.8%
307	Chronic Fatigue Syndrome	8.7%
308	Ophthalmoplegic Migraine	8.7%
309	Paraneoplastic Cerebellar Degeneration	8.6%
310	Pituitary Adenoma	8.6%
311	Pituitary Neoplasms	8.6%
312	Behcet Syndrome	8.5%
313	Waldenstrom Macroglobulinemia	8.4%
314	Multiple Myeloma	8.4%
315	Cardiac Tamponade	8.4%
316	Endocarditis	8.4%
317	Cardiac Arrest	8.4%
318	Heart failure	8.4%
319	Pericardial effusion	8.4%
320	Pericarditis	8.4%
321	Pneumopericardium	8.4%
322	Cor pulmonale	8.4%
323	Ventricular Outflow Obstruction	8.4%
324	Ventricular Dysfunction	8.4%
325	Cardiomyopathies	8.4%
326	Pleuropericarditis	8.4%
327	Cerebrovascular Disorders	8.4%
328	Cerebrovascular Insufficiency	8.4%
329	Persistent Vegetative State	8.4%
330	Miller Fisher Syndrome	8.4%
331	Motor Neuron Disease	8.3%
332	Trauma, Nervous System	8.2%
333	MPTP Poisoning	8.2%
334	Nervous System Neoplasms	8.1%
335	Neurologic Manifestations	8.1%
336	Neurotoxicity Syndromes	8.1%
337	Restless Legs Syndrome	8%
338	Juvenile Myoclonic Epilepsy	8%
339	Myoclonic Epilepsies, Progressive	8%
340	Angina Pectoris, Variant	8%
341	Hypertension, Renovascular	7.8%
342	Encephalomyelitis, Acute Disseminated	7.8%
343	Pseudoxanthoma Elasticum	7.8%
344	Reye Syndrome	7.8%
345	Hereditary Angioedema Type III	7.8%
346	Hereditary Angioedema Types I and II	7.8%
347	Hepatic Encephalopathy	7.8%
348	Heart Block	7.7%
349	Tachycardia	7.7%
350	Tachyarrhythmia	7.7%
351	Aortic coarctation	7.7%
352	Cor Triatriatum	7.7%
353	Coronary Vessel Anomalies	7.7%
354	Patent ductus arteriosus	7.7%
355	Ebstein Anomaly	7.7%
356	Heart Septal Defects	7.7%
357	Spinal Cord Neoplasms	7.7%
358	Tetralogy of Fallot	7.7%
359	Transposition of Great Vessels	7.7%
360	Hypoplastic Left Heart Syndrome	7.7%
361	Myelitis, Transverse	7.7%
362	Arachnoiditis	7.7%
363	Aseptic Meningitis	7.7%
364	Syringomyelia	7.7%
365	Essential Tremor	7.7%
366	Familial Tremor	7.7%
367	Pneumorrhachis	7.7%
368	Writer's Cramp	7.7%
369	Akathisia, Drug-Induced	7.6%
370	Canavan Disease	7.6%
371	Alexander Disease	7.6%
372	Friedreich Ataxia	7.5%
373	Polyradiculoneuropathy	7.4%
374	Polyradiculoneuritis	7.4%
375	Cardiac Output, High	7.3%
376	Myocardial Stunning	7.3%
377	Low Cardiac Output Syndrome	7.3%
378	Cardiomegaly	7.3%
379	Postpericardiotomy Syndrome	7.3%
380	Cardiac Hypertrophy	7.3%
381	Opsoclonus-Myoclonus Syndrome	7.2%
382	Rheumatic Heart Disease	7.2%
383	Sleep Wake Disorders	7.2%
384	Mitochondrial Encephalomyopathies	7.1%
385	Hepatic Vein Thrombosis	7%
386	Budd-Chiari Syndrome	7%
387	Brain Diseases, Metabolic, Inborn	7%
388	Pulmonary Infarction	6.9%
389	Dextrocardia	6.9%
390	Long QT Syndrome	6.9%
391	Lafora Disease	6.7%
392	Unverricht-Lundborg Syndrome	6.7%
393	Hypertrophic Cardiomyopathy	6.7%
394	Hypertrophic obstructive cardiomyopathy	6.7%
395	Central Nervous System Fungal Infections	6.7%
396	Conus Medullaris Syndrome	6.7%
397	Dural Arteriovenous Fistula	6.6%
398	Post-Traumatic Headache	6.5%
399	Tension Headache	6.5%
400	Epilepsy, Complex Partial	6.5%
401	Migraine Disorders	6.5%
402	Abdominal Migraine	6.5%
403	Status Migrainosus	6.5%
404	Cervicogenic Headache	6.5%
405	Dyskinesia, Drug-Induced	6.5%
406	Auditory Perceptual Disorders	6.5%
407	Autonomic Dysreflexia	6.3%
408	Rheumatoid Vasculitis	6.3%
409	Complex Regional Pain Syndromes	6.3%
410	Sick Sinus Syndrome	6.3%
411	Wernicke Encephalopathy	6.2%
412	AIDS Dementia Complex	6.2%
413	Adrenoleukodystrophy	6.1%
414	Granulomatosis with polyangiitis	6.1%
415	Tuberculosis, Meningeal	6%
416	Supravalvular aortic stenosis	6%
417	Lown-Ganong-Levine Syndrome	6%
418	Central Nervous System Bacterial Infections	5.9%
419	Kernicterus	5.8%
420	Empty Sella Syndrome	5.7%
421	Hyperpituitarism	5.7%
422	Hypopituitarism	5.7%
423	Hypophysitis	5.7%
424	Noonan Syndrome	5.7%
425	Diffuse Axonal Injury	5.6%
426	Brain Stem Neoplasms	5.6%
427	Peripheral Nerve Injuries	5.6%
428	Carcinoid Heart Disease	5.5%
429	Myasthenia Gravis	5.5%
430	Lambert-Eaton Myasthenic Syndrome	5.5%
431	Frontotemporal dementia	5.3%
432	Scrapie	5.3%
433	Central Cord Syndrome	5.3%
434	Chorea	5.2%
435	Marfan Syndrome	5.2%
436	Subacute Sclerosing Panencephalitis	5.2%
437	Adams-Stokes Syndrome	5.2%
438	Atrioventricular Block	5.2%
439	Bundle-Branch Block	5.2%
440	Atrial Premature Complexes	5.2%
441	Sinoatrial Block	5.2%
442	Tachycardia, Paroxysmal	5.2%
443	Supraventricular tachycardia	5.2%
444	Tachycardia, Ventricular	5.2%
445	Wolff-Parkinson-White Syndrome	5.2%
446	Tachycardia, Reciprocating	5.2%
447	Aortopulmonary Septal Defect	5.2%
448	Double Outlet Right Ventricle	5.2%
449	Endocardial Cushion Defects	5.2%
450	Myocardial bridging	5.2%
451	Aorticopulmonary Septal Defect	5.2%
452	Guillain-Barre Syndrome	5.2%
453	Subacute Bacterial Endocarditis	5.2%
454	Aortic Valve Insufficiency	5.1%
455	Restrictive cardiomyopathy	5.1%
456	Endocardial Fibroelastosis	5.1%
457	Heart Rupture, Post-Infarction	5.1%
458	Mitral Valve Insufficiency	5.1%
459	Mitral Valve Stenosis	5.1%
460	Myocarditis	5.1%
461	Pericarditis, Constrictive	5.1%
462	Pulmonary Valve Insufficiency	5.1%
463	Tricuspid Valve Insufficiency	5.1%
464	Tricuspid Valve Stenosis	5.1%
465	Ventricular Dysfunction, Left	5.1%
466	Right Ventricular Dysfunction	5.1%
467	Endomyocardial Fibrosis	5.1%
468	Carditis	5.1%
469	Heart Failure, Systolic	5.1%
470	Heart Failure, Diastolic	5.1%
471	Sleep Disorders, Circadian Rhythm	5%
472	Brain Contusion	5%
473	Botulism	4.9%
474	Central Nervous System Cysts	4.9%
475	Brain Concussion	4.9%
476	Meningitis, Cryptococcal	4.8%
477	Meningitis, Listeria	4.8%
478	Meningitis, Haemophilus	4.8%
479	Meningitis, Pneumococcal	4.8%
480	Dysautonomia	4.8%
481	Vagus Nerve Disorder	4.8%
482	Glossopharyngeal Neuralgia	4.8%
483	Abducens Nerve Diseases	4.8%
484	Heavy Metal Poisoning, Nervous System	4.8%
485	Neuromuscular Junction Diseases	4.8%
486	Tauopathies	4.8%
487	Trochlear Nerve Diseases	4.8%
488	Peripheral Nervous System Diseases	4.8%
489	Cluster Headache	4.7%
490	Migraine with Aura	4.7%
491	Familial Hemiplegic Migraine	4.7%
492	Chronic Paroxysmal Hemicrania	4.7%
493	SUNCT Syndrome	4.7%
494	Paroxysmal Hemicrania	4.7%
495	Romano-Ward Syndrome	4.6%
496	Neuromyelitis Optica	4.4%
497	Torticollis	4.4%
498	Olfactory Nerve Injuries	4.4%
499	Sinus Arrhythmia	4.4%
500	Atrial Fibrillation	4.4%
501	Atrial Flutter	4.4%
502	Edema, Cardiac	4.4%
503	Progressive bulbar palsy	4.4%
504	Ventricular Fibrillation	4.4%
505	Ventricular Flutter	4.4%
506	Parasystole	4.4%
507	Paroxysmal atrial fibrillation	4.4%
508	Bradycardia	4.4%
509	Diabetic Cardiomyopathies	4.4%
510	Bulbar palsy	4.4%
511	Cardiomyopathy, Alcoholic	4.4%
512	Ectopia Cordis	4.4%
513	Sudden Cardiac Death	4.4%
514	Left Ventricular Hypertrophy	4.4%
515	Right Ventricular Hypertrophy	4.4%
516	Single umbilical artery	4.4%
517	Chagas Cardiomyopathy	4.4%
518	Refsum Disease	4.3%
519	Myopathy	4.2%
520	Optic Neuropathy	4.2%
521	Horner Syndrome	4.2%
522	Alice in Wonderland Syndrome	4.2%
523	Causalgia	4.1%
524	Facial Nerve Diseases	4.1%
525	Craniocerebral Trauma	4.1%
526	Parasomnia	4.1%
527	Dyssomnias	4.1%
528	Vestibulocochlear Nerve Diseases	4.1%
529	Decerebrate State	4.1%
530	Hemiparesis	4.1%
531	Hydranencephaly	4.1%
532	Meningism	4.1%
533	Neural Tube Defects	4.1%
534	Paresis	4.1%
535	Seizures	4.1%
536	Sensation Disorders	4.1%
537	Tethered Cord Syndrome	4.1%
538	Central Nervous System Neoplasms	4.1%
539	Complex partial seizures	4.1%
540	Iniencephaly	4.1%
541	Craniorachischisis	4.1%
542	Exencephaly	4.1%
543	Monoparesis	4.1%
544	Septo-Optic Dysplasia	4.1%
545	Cortical Dysplasia	4.1%
546	Neurogenic Inflammation	4.1%
547	Gait Disorders, Neurologic	4.1%
548	Neuromuscular Manifestations	4.1%
549	Malformations of Cortical Development	4.1%
550	Sweating, Gustatory	4.1%
551	Auriculotemporal Syndrome	4.1%
552	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4%
553	Hyperprolactinemia	4%
554	Tachycardia, Atrioventricular Nodal Reentry	4%
555	Tachycardia, Ectopic Atrial	4%
556	Tachycardia, Ectopic Junctional	4%
557	Sinus Tachycardia	4%
558	Torsades de Pointes	4%
559	Accelerated Idioventricular Rhythm	4%
560	Pick Disease of the Brain	4%
561	Truncus Arteriosus, Persistent	4%
562	Choroid Plexus Papilloma	4%
563	Facial Nerve Injuries	4%
564	Tuberous Sclerosis	3.9%
565	Dyspnea, Paroxysmal	3.9%
566	Multiple Sclerosis	3.9%
567	Tuberculosis, Central Nervous System	3.8%
568	Jet Lag Syndrome	3.8%
569	Pupil Disorders	3.7%
570	Neurobehavioral Manifestations	3.7%
571	Paraneoplastic Encephalomyelitis	3.6%
572	Myasthenia Gravis, Autoimmune, Experimental	3.6%
573	West Nile Fever	3.6%
574	Uveomeningoencephalitic Syndrome	3.6%
575	Galactosemias	3.6%
576	Urea Cycle Disorders, Inborn	3.6%
577	Tyrosinemias	3.6%
578	Vertigo	3.6%
579	Alcohol-Induced Disorders, Nervous System	3.6%
580	Acromegaly	3.5%
581	Aortic Valve Prolapse	3.5%
582	Tricuspid Valve Prolapse	3.5%
583	Takotsubo Cardiomyopathy	3.5%
584	Reflex Sympathetic Dystrophy	3.5%
585	Nocturnal Myoclonus Syndrome	3.5%
586	Ophthalmoplegia	3.5%
587	External Ophthalmoplegia	3.5%
588	Turner Syndrome	3.4%
589	Neuroaspergillosis	3.3%
590	Homocystinuria	3.3%
591	Leigh Disease	3.3%
592	Voice Disorders	3.2%
593	Voice Disturbance	3.2%
594	Tardive Dyskinesia	3.2%
595	Smith-Magenis syndrome	3.2%
596	Kearns-Sayre syndrome	3.2%
597	Vocal Cord Paralysis	3.1%
598	Pseudorabies	3.1%
599	Acrodynia	3%
600	Menkes Kinky Hair Syndrome	3%
601	Sinus Arrest, Cardiac	3%
602	Charcot-Marie-Tooth Disease	3%
603	Neurosyphilis	2.9%
604	Reflex, Abnormal	2.9%
605	Hyporeflexia	2.9%
606	Hyperreflexia	2.9%
607	Prolactinoma	2.8%
608	Growth Hormone-Secreting Pituitary Adenoma	2.8%
609	Alcohol Withdrawal Seizures	2.8%
610	Williams Syndrome	2.8%
611	Myotonia Congenita	2.7%
612	Cerebrospinal Fluid Otorrhea	2.7%
613	Cerebrospinal Fluid Rhinorrhea	2.7%
614	Neuritis, Autoimmune, Experimental	2.7%
615	Gait Ataxia	2.7%
616	Zellweger Syndrome	2.7%
617	Lyme Neuroborreliosis	2.7%
618	Neuritis	2.6%
619	Polyneuritis	2.6%
620	Radiculitis	2.6%
621	Polyneuropathy	2.6%
622	Mononeuritis	2.6%
623	Mononeuropathies	2.6%
624	Brachial Plexus Neuropathies	2.6%
625	Radiculopathy	2.6%
626	Mononeuropathy Multiplex	2.6%
627	Nerve Root Compression	2.6%
628	Brachial Plexus Neuritis	2.5%
629	Neuralgic Amyotrophy	2.5%
630	Kartagener Syndrome	2.5%
631	Myotonic Dystrophy	2.5%
632	Nelson Syndrome	2.5%
633	Akathisia	2.4%
634	Restlessness	2.4%
635	Psychomotor Agitation	2.4%
636	Coma, Post-Head Injury	2.4%
637	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.3%
638	Myositis	2.2%
639	Optic Atrophy	2.2%
640	Optic Neuritis	2.2%
641	Papilledema	2.2%
642	Strabismus	2.2%
643	Tolosa-Hunt Syndrome	2.2%
644	Isaacs syndrome	2.2%
645	Arsenic Poisoning	2.2%
646	Myotonic Disorders	2.2%
647	Myasthenic Syndromes, Congenital	2.2%
648	Multiple Sclerosis, Chronic Progressive	2.2%
649	Multiple Sclerosis, Relapsing-Remitting	2.2%
650	Diabetic Neuropathies	2.2%
651	Facial Injuries	2.2%
652	Facial Neuralgia	2.2%
653	Diabetic Amyotrophy	2.2%
654	Diabetic Autonomic Neuropathy	2.2%
655	Sleep Talking	2.2%
656	Manganese Poisoning	2.2%
657	Sleep Disorders, Intrinsic	2.2%
658	Orthostatic intolerance	2.2%
659	Acoustic Neuroma	2.2%
660	Anosmia	2.2%
661	Ataxia	2.2%
662	Athetosis	2.2%
663	Catalepsy	2.2%
664	Dystonia	2.2%
665	Hemiplegia	2.2%
666	Locked-In Syndrome	2.2%
667	Meningeal Neoplasms	2.2%
668	Meningomyelocele	2.2%
669	Muscle Hypertonia	2.2%
670	Muscle hypotonia	2.2%
671	Myoclonus	2.2%
672	Myotonia	2.2%
673	Neuralgia	2.2%
674	Paraplegia	2.2%
675	Pseudobulbar Palsy	2.2%
676	Quadriplegia	2.2%
677	Spasm	2.2%
678	Spastic Paraplegia	2.2%
679	Status Epilepticus	2.2%
680	Taste Disorders	2.2%
681	Tremor	2.2%
682	Spina Bifida	2.2%
683	Monoplegia	2.2%
684	Hypokinesia	2.2%
685	Paraparesis	2.2%
686	Bradykinesia	2.2%
687	Waxy flexibility	2.2%
688	Action Tremor	2.2%
689	Resting Tremor	2.2%
690	Dysosmia	2.2%
691	Quadriparesis	2.2%
692	Mercury Poisoning, Nervous System	2.2%
693	Olfaction Disorders	2.2%
694	Myokymia	2.2%
695	Lead Poisoning, Nervous System	2.2%
696	Vestibular Neuronitis	2.2%
697	Somatosensory Disorders	2.2%
698	Neuropathic pain	2.2%
699	Hyperkinesia	2.2%
700	Intention tremor	2.2%
701	Glycogen storage disease type II	2.1%
702	Alstrom Syndrome	2.1%
703	Optic Nerve Glioma	2.1%
704	Toxoplasmosis, Congenital	2.1%
705	Malaria, Cerebral	2.1%
706	Neurocysticercosis	2.1%
707	Gait Apraxia	2.1%
708	Waterhouse-Friderichsen Syndrome	2.1%
709	Tarsal Tunnel Syndrome	2.1%
710	Cauda Equina Syndrome	2.1%
711	Amyloid Neuropathies, Familial	2%
712	Vision Disorders	2%
713	Metamorphopsia	2%
714	Visual Impairment	2%
715	Fibromyalgia	2%
716	Medial Tibial Stress Syndrome	2%
717	Facial Hemiatrophy	1.9%
718	Melkersson-Rosenthal Syndrome	1.9%
719	Mitochondrial Myopathies	1.9%
720	Anisocoria	1.9%
721	Confusion	1.9%
722	Facial paralysis	1.9%
723	Lethargy	1.9%
724	Memory Disorders	1.9%
725	Muscle Cramp	1.9%
726	Perceptual Disorders	1.9%
727	Psychomotor Disorders	1.9%
728	Tonic Pupil	1.9%
729	Eosinophilia-Myalgia Syndrome	1.9%
730	Anhedonia	1.9%
731	Disorientation	1.9%
732	Facial Paresis	1.9%
733	Memory Loss	1.9%
734	Hemisensory Neglect	1.9%
735	Dysacusis	1.9%
736	Sleep Bruxism	1.9%
737	Anencephaly	1.9%
738	Meningocele	1.9%
739	Muscular Atrophy	1.9%
740	Respiratory Paralysis	1.9%
741	Encephalocele	1.9%
742	Tetany	1.9%
743	Carpal Tunnel Syndrome	1.8%
744	neurofibroma	1.8%
745	Sciatica	1.8%
746	Duane Retraction Syndrome	1.7%
747	Consciousness Disorders	1.7%
748	Mental Retardation	1.7%
749	Muscle Weakness	1.7%
750	Depressed Level of Consciousness	1.7%
751	Mental deficiency	1.7%
752	Intellectual Disability	1.7%
753	Mobius Syndrome	1.7%
754	Bell Palsy	1.7%
755	Catatonia	1.7%
756	Herpes Zoster Oticus	1.7%
757	Familial Periodic Paralysis	1.7%
758	Aphonia	1.7%
759	Sleep Deprivation	1.7%
760	Dysphonia	1.7%
761	Gaucher Disease	1.6%
762	Myalgia	1.5%
763	Neuronal Ceroid-Lipofuscinoses	1.5%
764	Sciatic Neuropathy	1.5%
765	Ulnar Neuropathies	1.5%
766	Lesion of Sciatic Nerve	1.5%
767	Ulnar Neuritis	1.5%
768	Radial nerve compression	1.5%
769	Radial Tunnel Syndrome	1.5%
770	Peroneal Neuropathies	1.5%
771	Radial Neuropathy	1.5%
772	Median Neuropathy	1.5%
773	Sciatic Nerve Palsy	1.5%
774	Femoral Neuropathy	1.5%
775	Tibial Neuropathy	1.5%
776	Ulnar Nerve Palsy	1.5%
777	Postural Orthostatic Tachycardia Syndrome	1.5%
778	Radial nerve palsy	1.5%
779	Classical Lissencephalies and Subcortical Band Heterotopias	1.4%
780	Aicardi's syndrome	1.4%
781	Hoarseness	1.4%
782	Cockayne Syndrome	1.4%
783	Alcohol Withdrawal Delirium	1.4%
784	Cubital Tunnel Syndrome	1.4%
785	Niemann-Pick Disease, Type C	1.3%
786	Holoprosencephaly	1.3%
787	Tay-Sachs Disease	1.3%
788	Esotropia	1.3%
789	Exotropia	1.3%
790	Sleep Apnea Syndromes	1.3%
791	Polymyositis	1.3%
792	Disorders of Excessive Somnolence	1.3%
793	Sleep Initiation and Maintenance Disorders	1.3%
794	Night Terrors	1.3%
795	Somnambulism	1.3%
796	Trigeminal Nerve Disorder	1.3%
797	Transient Insomnia	1.3%
798	Sleep Paralysis	1.3%
799	Chronic Insomnia	1.3%
800	REM Sleep Behavior Disorder	1.3%
801	Hypersomnia	1.3%
802	Dermal Sinus	1.3%
803	Dysgeusia	1.3%
804	Formication	1.3%
805	Hyperalgesia	1.3%
806	Hyperesthesia	1.3%
807	Hypesthesia	1.3%
808	Language Disorders	1.3%
809	Numbness	1.3%
810	Paresthesia	1.3%
811	Paraparesis, Spastic	1.3%
812	Spina Bifida Cystica	1.3%
813	Trismus	1.3%
814	Spina Bifida Occulta	1.3%
815	Epilepsia Partialis Continua	1.3%
816	Hypogeusia	1.3%
817	Meningeal Carcinomatosis	1.3%
818	Brown-Sequard Syndrome	1.3%
819	Lissencephaly	1.3%
820	Polymicrogyria	1.3%
821	Pachygyria	1.3%
822	Schizencephaly	1.3%
823	Lockjaw	1.3%
824	Allodynia	1.3%
825	Lead Poisoning, Nervous System, Childhood	1.3%
826	Lead Poisoning, Nervous System, Adult	1.3%
827	Periventricular Nodular Heterotopia	1.3%
828	Ageusia	1.3%
829	Optic Atrophy, Hereditary, Leber	1.2%
830	Eye Injuries	1.1%
831	Muscular Dystrophy	1.1%
832	Congenital nystagmus	1.1%
833	Orbital Myositis	1.1%
834	Alexia	1.1%
835	Dyslexia	1.1%
836	Diplopia	1.1%
837	Muscle Rigidity	1.1%
838	Muscle Spasticity	1.1%
839	Scotoma	1.1%
840	Photophobia	1.1%
841	Cogwheel Rigidity	1.1%
842	Hemifacial Spasm	1.1%
843	Amaurosis	1.1%
844	Blindness	1.1%
845	Nuchal Rigidity	1.1%
846	Pyomyositis	1.1%
847	Agnosia	1.1%
848	Apraxias	1.1%
849	Hallucinations	1.1%
850	Hemianopsia	1.1%
851	Hyperacusis	1.1%
852	Tinnitus	1.1%
853	Visual Agnosia	1.1%
854	Anosognosia	1.1%
855	Wernicke-Korsakoff Syndrome	1.1%
856	Phonophobia	1.1%
857	Hearing Loss	1.1%
858	Sarcopenia	1.1%
859	Amnesia	1%
860	Delirium	1%
861	Dissociative Amnesia	1%
862	Color blindness	1%
863	Global Amnesia	1%
864	Cri-du-Chat Syndrome	1%
865	Down Syndrome	1%
866	Trisomy 21	1%
867	POEMS Syndrome	1%
868	Meningioma	1%
869	Microcephaly	1%
870	Macrocephaly	1%
871	Hypokalemic periodic paralysis	1%
872	Porencephaly	1%
873	Neurofibrosarcoma	1%
874	Polyradiculopathy	0.9%
875	Prader-Willi Syndrome	0.9%
876	Phantom pain	0.9%
877	Phantom Limb Pain	0.9%
878	Sleep Apnea, Obstructive	0.8%
879	Sleep Apnea, Central	0.8%
880	Narcolepsy	0.8%
881	Trigeminal Neuralgia	0.8%
882	Kleine-Levin Syndrome	0.8%
883	Agraphia	0.8%
884	Anomia	0.8%
885	Cluttering	0.8%
886	Language Development Disorders	0.8%
887	Speech Disorders	0.8%
888	Syncope	0.8%
889	Stupor	0.8%
890	Dysgraphia	0.8%
891	Presyncope	0.8%
892	Dyslalia	0.8%
893	Rubinstein-Taybi Syndrome	0.7%
894	Eye Burns	0.7%
895	Welander Distal Myopathy	0.7%
896	Amaurosis Fugax	0.7%
897	Blindness, Cortical	0.7%
898	Dyscalculia	0.7%
899	Rett Syndrome	0.7%
900	Deafness	0.7%
901	Hearing Loss, Sudden	0.7%
902	Gerstmann Syndrome	0.7%
903	Hearing Loss, Bilateral	0.7%
904	Hearing Loss, High-Frequency	0.7%
905	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
906	Prosopagnosia	0.7%
907	Apraxia, Ideomotor	0.7%
908	Charles Bonnet Syndrome	0.7%
909	Hearing Loss, Unilateral	0.7%
910	Complete Hearing Loss	0.7%
911	Alien Hand Syndrome	0.7%
912	Deaf Mutism	0.7%
913	Dermatomyositis	0.6%
914	Corneal Scar	0.6%
915	Muscular Dystrophy, Duchenne	0.6%
916	Retrograde amnesia	0.6%
917	Amnesia, Anterograde	0.6%
918	Cataplexy	0.6%
919	Aphasia	0.6%
920	Articulation Disorders	0.6%
921	Echolalia	0.6%
922	Stuttering	0.6%
923	Dysphasia	0.6%
924	Fragile X Syndrome	0.6%
925	Mutism	0.5%
926	Selective Mutism	0.5%
927	Dysarthria	0.5%
928	Corneal Perforation	0.4%
929	Mucopolysaccharidosis II	0.4%
930	Alexia, Pure	0.4%

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