MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Perioral Dermatitis

(UMLS:C0263449)

Definition:: A papular eruption of unknown etiology that progresses to residual papular erythema and scaling usually confined to the area of the mouth, and almost exclusively occurring in young women. It may also be localized or extend to involve the eyelids and adjacent glabella area of the forehead (periocular dermatitis). (Dorland, 28th ed)
UMLS ID:: C0263449
MeSH ID:: D019557

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.174.550|C17.800.271.250

Synonym(s)

Perioral Dermatitis

Dermatitis;perioral

POD - Perioral dermatitis

Perioral dermatitis

dermatitis perioral

dermatitis; perioral

perioral dermatitis

perioral; dermatitis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	tofacitinib	FAERS: 2	US FAERS
2	4-Aminopyridine	FAERS: 1	US FAERS
3	AN2728	FAERS: 1	US FAERS
4	Anoro Ellipta	FAERS: 1	US FAERS
5	Beclomethasone	FAERS: 1	US FAERS
6	Fluticasone	FAERS: 1	US FAERS
7	Isotretinoin	FAERS: 1	US FAERS
8	azelastine	FAERS: 1	US FAERS
9	montelukast	FAERS: 1	US FAERS
10	montelukast	FAERS: 1	US FAERS
11	obeticholic acid	FAERS: 1	US FAERS
12	pomalidomide	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Contact Dermatitis	53.3%
2	Eczema	53.3%
3	Intertrigo	53.3%
4	Neurodermatitis	53.3%
5	Pyoderma Gangrenosum	48%
6	Dermatitis Herpetiformis	43.2%
7	Acrodermatitis	42.7%
8	Gianotti-Crosti Syndrome	42.7%
9	Dermatitis, Atopic	41.9%
10	Dermatitis, Phototoxic	41.8%
11	Phototoxicity	41.8%
12	Lupus Erythematosus, Cutaneous	41.4%
13	Panniculitis	41.4%
14	Systemic Scleroderma	41.4%
15	Morphea	41.4%
16	Breast Diseases	40.9%
17	Exanthema	40.9%
18	Hair Diseases	40.9%
19	Hand Dermatoses	40.9%
20	keratoacanthoma	40.9%
21	Keratosis	40.9%
22	Nail Diseases	40.9%
23	Photosensitivity Disorders	40.9%
24	Prurigo	40.9%
25	Pyoderma	40.9%
26	Rosacea	40.9%
27	Sebaceous Gland Diseases	40.9%
28	Skin Diseases, Vesiculobullous	40.9%
29	Skin Ulcer	40.9%
30	Sweat Gland Diseases	40.9%
31	Skin Diseases, Papulosquamous	40.9%
32	Skin Diseases, Vascular	40.9%
33	Acneiform Eruptions	40.9%
34	Ocular Rosacea	40.9%
35	Subcorneal pustular dermatosis	40.9%
36	Erythematotelangiectatic Rosacea	40.9%
37	Papulopustular Rosacea	40.9%
38	Chronic Actinic Dermatitis	40.9%
39	Acne Vulgaris	40%
40	Erythema Multiforme	40%
41	Rhinophyma	40%
42	Acne	40%
43	Dermatitis, Irritant	39.3%
44	Pityriasis Lichenoides et Varioliformis Acuta	35.3%
45	Pityriasis Lichenoides	35.3%
46	Dermatitis, Photoallergic	34.8%
47	Foot Ulcer	34.7%
48	Epidermolysis Bullosa	34.3%
49	Dermatitis, Occupational	32.9%
50	Diaper Rash	32.5%
51	Xeroderma Pigmentosum	32.2%
52	Foot Diseases	32.1%
53	Sebaceous Gland Neoplasms	32%
54	Porokeratosis	32%
55	Keratoderma, Palmoplantar	32%
56	Dermatitis, Allergic Contact	31.6%
57	Skin Abnormalities	31%
58	Skin Diseases, Infectious	31%
59	Skin Neoplasms	31%
60	Pigmentation Disorders	31%
61	Panniculitis, Lupus Erythematosus	30.8%
62	Lipomatosis	30.5%
63	Pruritus	30.5%
64	Erythema	30.5%
65	Necrolytic Migratory Erythema	30.5%
66	Cutaneous Fistula	30.5%
67	Nephrogenic Fibrosing Dermopathy	30.5%
68	Nephrogenic Systemic Fibrosis	30.5%
69	Necrobiosis Lipoidica Diabeticorum	29.8%
70	Erythema Nodosum	29.5%
71	Acne Conglobata	29.5%
72	Urticaria Pigmentosa	27.5%
73	Xeroderma	27%
74	Toxic Epidermal Necrolysis	26.9%
75	Stevens-Johnson Syndrome	26.9%
76	Dermatomyositis	26.9%
77	Anhidrosis	26.7%
78	Cholesteatoma	26.7%
79	Pressure Ulcer	26.7%
80	Drug Eruptions	26.7%
81	Folliculitis	26.7%
82	Foot Dermatoses	26.7%
83	Gynecomastia	26.7%
84	Hypertrichosis	26.7%
85	Hypohidrosis	26.7%
86	Hypotrichosis	26.7%
87	Leg Ulcer	26.7%
88	Lupus Erythematosus, Discoid	26.7%
89	Miliaria	26.7%
90	Parakeratosis	26.7%
91	Parapsoriasis	26.7%
92	Pityriasis	26.7%
93	Psoriasis	26.7%
94	Sweet Syndrome	26.7%
95	Hidradenitis	26.7%
96	Onycholysis	26.7%
97	Miliaria Rubra	26.7%
98	Hyperpigmentation	26.7%
99	Lichenoid Eruptions	26.7%
100	Chloracne	26.7%
101	Scleroderma, Limited	26.7%
102	Erythema Induratum	25.7%
103	Cutis Laxa	24.3%
104	Mastocytosis	24.2%
105	Connective Tissue Diseases	23.8%
106	Papillon-Lefevre Disease	23.5%
107	Erythema Infectiosum	23.5%
108	Exanthema Subitum	23.3%
109	Ectodermal Dysplasia	22.9%
110	Aplasia Cutis Congenita	22.9%
111	Pseudoxanthoma Elasticum	22.3%
112	Tinea Capitis	21.2%
113	Onychomycosis	21.2%
114	Dermatitis	20.5%
115	Facial Dermatoses	20.5%
116	Acantholysis	20.3%
117	Breast Cyst	20.3%
118	Actinic keratosis	20.3%
119	Pemphigoid, Benign Mucous Membrane	20.3%
120	Pemphigus	20.3%
121	Piedra	20.3%
122	Sunburn	20.3%
123	Argyria	20%
124	Hirsutism	20%
125	Lactation Disorder	20%
126	Mastitis	20%
127	Urticaria	20%
128	Perioral Dermatitis	20%
129	Granuloma Annulare	19.9%
130	Adiposis Dolorosa	19.8%
131	Pruritus Vulvae	19.8%
132	Lichen Planus	19.8%
133	Melanosis	19.8%
134	Chloasma	19.8%
135	Pityriasis Rosea	19.8%
136	Pityriasis Rubra Pilaris	19.8%
137	Vitiligo	19.8%
138	Lichen Nitidus	19.8%
139	Mastocytoma	19.8%
140	Pruritus Ani	19.8%
141	Ecthyma	19.7%
142	Acute Generalized Exanthematous Pustulosis	19.6%
143	Hyperkeratosis, Epidermolytic	19.4%
144	Ichthyosis, X-Linked	17.9%
145	Sjogren-Larsson Syndrome	17.8%
146	Behcet Syndrome	17.5%
147	Hidradenitis Suppurativa	16.9%
148	Acanthosis Nigricans	16.4%
149	Alopecia Areata	16.4%
150	Lentigo	16.4%
151	Serum Sickness	16.4%
152	Dermatomycoses	16.2%
153	Mucocutaneous Lymph Node Syndrome	16.2%
154	Skin Diseases, Bacterial	16.2%
155	Lipodystrophy	16%
156	Livedo Reticularis	16%
157	Malignant Atrophic Papulosis	16%
158	Polyarteritis Nodosa	15.8%
159	Takayasu Arteritis	15.8%
160	Albinism	15.5%
161	Tinea Pedis	15.3%
162	Erythema Chronicum Migrans	15.2%
163	Alopecia	15.1%
164	Sweating, Gustatory	15.1%
165	Androgenetic Alopecia	15.1%
166	Auriculotemporal Syndrome	15.1%
167	Lice Infestations	14.9%
168	Varicose Ulcer	14.9%
169	Breast Neoplasms, Male	14.9%
170	Triple Negative Breast Neoplasms	14.9%
171	Galactorrhea	14.8%
172	Collagen Diseases	13.6%
173	Mixed Connective Tissue Disease	13.6%
174	Nail-Patella Syndrome	13.6%
175	Mucinoses	13.6%
176	Porphyrias, Hepatic	13.5%
177	Mycetoma	13.1%
178	Lichen Planus, Oral	12.6%
179	Larva Migrans	12.1%
180	Leishmaniasis	12.1%
181	Molluscum Contagiosum	12.1%
182	Angioedema	12%
183	Onchocerciasis	11.9%
184	Chromoblastomycosis	11.8%
185	Dermatophytosis	11.8%
186	Sporotrichosis	11.8%
187	Tinea	11.8%
188	Tinea Versicolor	11.8%
189	Trichophytosis	11.8%
190	Hyalohyphomycosis	11.8%
191	Cartilage Diseases	10.7%
192	Rheumatism	10.7%
193	Chondromalacia	10.7%
194	Lupus Erythematosus, Systemic	10.3%
195	Overlap syndrome	10.3%
196	Warts	10.2%
197	Candidiasis, Chronic Mucocutaneous	9.9%
198	Cutaneous Candidiasis	9.9%
199	Erysipelas	9.8%
200	Leishmaniasis, Cutaneous	9.8%
201	Staphylococcal Skin Infections	9.8%
202	Variegate Porphyria	9.8%
203	Acute intermittent porphyria	9.8%
204	Porphyria Cutanea Tarda	9.8%
205	Eczema Herpeticum	9.8%
206	Erythrasma	9.8%
207	Carcinoma, Lobular	9.8%
208	CREST Syndrome	9.8%
209	Arthritis, Psoriatic	9.8%
210	Fusariosis	9.7%
211	Scleromyxedema	8.9%
212	Hereditary Angioedema Type III	8.7%
213	Hereditary Angioedema Types I and II	8.7%
214	Giant Cell Arteritis	8.7%
215	Temporal Arteritis	8.7%
216	Angioedemas, Hereditary	8.3%
217	Epidermodysplasia Verruciformis	8.2%
218	Herpes Labialis	8.2%
219	Diabetic Foot	8.2%
220	Staphylococcal Scalded Skin Syndrome	8.1%
221	Dupuytren Contracture	8%
222	Peutz-Jeghers Syndrome	7.5%
223	Blastomycosis	7.4%
224	HIV-Associated Lipodystrophy Syndrome	7.3%
225	carbuncle	7.2%
226	Condylomata Acuminata	7.1%
227	Furunculosis	7%
228	furuncle	7%
229	Impetigo	6.9%
230	Mesenteric Panniculitis	6.8%
231	Panniculitis, Peritoneal	6.8%
232	Tietze's Syndrome	6.8%
233	Orbital Cellulitis	6.8%
234	Myxoid cyst	6.8%
235	Rhinoscleroma	6.7%
236	Cellulitis	6.7%
237	Myxedema	6.7%
238	Menkes Kinky Hair Syndrome	6.5%
239	Osteochondritis	5.5%
240	Polymyalgia Rheumatica	5.5%
241	Osteogenesis Imperfecta	5.4%
242	Keloid	5.3%
243	Noonan Syndrome	5%
244	Rheumatoid Arthritis	4.5%
245	Juvenile arthritis	4.5%
246	Marfan Syndrome	4.5%
247	Lupus Nephritis	4.4%
248	Homocystinuria	4.4%
249	Rheumatoid Nodule	3.9%
250	Laryngomalacia	3.9%
251	Pectus carinatum	3.9%
252	Felty Syndrome	3.3%
253	Bronchomalacia	3.3%
254	Tracheomalacia	3.3%
255	Rheumatoid Vasculitis	2.8%
256	Mucopolysaccharidosis III	2.8%
257	Sicca Syndrome	2.5%
258	Sjogren's Syndrome	2.5%
259	Lupus Vasculitis, Central Nervous System	2%
260	Mucopolysaccharidosis II	1.9%

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