MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Raynaud Disease

(UMLS:C0034734)

Definition:: An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress.
UMLS ID:: C0034734
MeSH ID:: D011928

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.617.812

Synonym(s)

Raynaud Disease

Disease;Raynauds

RAYNAUD DISEASE

RAYNAUDS DISEASE

Raynaud

Raynaud disease

Raynaud's Disease

Raynaud's disease

Raynaud's syndrome

10.

Raynauds disease

11.

disease raynaud

12.

disease raynaud's

13.

disease raynauds

14.

raynaud

15.

raynaud disease

16.

raynaud s disease

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Alprostadil	11310497	CTD
2	Arsenicals	12296288	CTD
3	Atenolol	6109	CTD
4	Bleomycin	View details 70274 77726 81878 1702313 2413982 2423995 2456930 2472472 6162955 6163385 6168223 6173125 6174061 6183087 6846998 7689922 8652248 9415644	CTD
5	Bromocriptine	561947 3117594 8977979	CTD
6	Citalopram	17103176	CTD
7	Clonidine	2057015	CTD
8	Cocaine	11642523 12296288	CTD
9	Cytarabine	6846998	CTD
10	Dextroamphetamine	18240233	CTD
11	Docosahexaenoic Acids	2536517	CTD
12	Doxorubicin	6846998 7689922	CTD
13	Eicosapentaenoic Acid	2536517	CTD
14	Epoprostenol	2875251	CTD
15	Fluorescein	17608774	CTD
16	Fluorouracil	10023329	CTD
17	Fluoxetine	9171912	CTD
18	Gemfibrozil	8422571	CTD
19	Griseofulvin	5414890	CTD
20	Hydroxyurea	6846998 12620292	CTD
21	Iloprost	16363279	CTD
22	Indomethacin	6614039	CTD
23	Leucovorin	10023329	CTD
24	Methyldopa	6809193	CTD
25	Methylphenidate	18240233	CTD
26	Metoprolol	12090909	CTD
27	Nifedipine	View details 3513504 6861634 8740329 11104295	CTD
28	Oxprenolol	6109	CTD
29	Pentoxifylline	12427911 14504440	CTD
30	Polyvinyl Chloride	16977343	CTD
31	Prazosin	6124197 7903757	CTD
32	Propranolol	6109 520027 6115999	CTD
33	Simvastatin	9759786	CTD
34	Sulfasalazine	6104805 6146597	CTD
35	Timolol	2323696	CTD
36	Vinblastine	View details 70274 77726 81878 1702313 2413982 2423995 2456930 2472472 6162955 6163385 6168223 6173125 6174061 6183087 6846998 9415644	CTD
37	Vincristine	6846998 7689922 15543016	CTD
38	liposomal amphotericin B	8901182 9470422	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Erythromelalgia	46.7%
2	Periphlebitis	44.4%
3	Phlebitis	44.4%
4	Blue Toe Syndrome	37.9%
5	Postphlebitic Syndrome	36.3%
6	Aneurysm	31%
7	Angiomatosis	31%
8	Aortic Diseases	31%
9	Arterial Occlusive Diseases	31%
10	Hyperemia	31%
11	Hypotension	31%
12	Superior Vena Cava Syndrome	31%
13	Telangiectasis	31%
14	Vasculitis	31%
15	Venous Insufficiency	31%
16	Embolism and Thrombosis	31%
17	Angiodysplasia	31%
18	Capillary Leak Syndrome	31%
19	Prehypertension	31%
20	Thrombophlebitis	30.4%
21	Myocardial Ischemia	27.9%
22	Aortic Aneurysm	26.7%
23	Aortitis	26.7%
24	Leriche Syndrome	26.7%
25	Thromboangiitis Obliterans	26.7%
26	May-Thurner Syndrome	26.4%
27	Livedo Reticularis	23.3%
28	Vascular System Injuries	22%
29	Retinal Vein Occlusion	21.7%
30	Compartment syndromes	20.9%
31	Hepatic Veno-Occlusive Disease	20.9%
32	Peliosis Hepatis	20.9%
33	Varicocele	20.9%
34	Cerebrovascular Disorders	20.5%
35	Diabetic Angiopathies	20.5%
36	Reperfusion Injury	20.5%
37	Splenic Infarction	20.5%
38	Cerebrovascular Insufficiency	20.5%
39	Vascular Neoplasms	20.5%
40	Spinal Cord Vascular Diseases	20.5%
41	Vasoplegia	20.5%
42	Hemorrhoids	20.2%
43	Thoracic Outlet Syndrome	20.2%
44	Aneurysm, Dissecting	20%
45	Arteriosclerosis	20%
46	Arteritis	20%
47	Embolism	20%
48	Fibromuscular Dysplasia	20%
49	Malignant Hypertension	20%
50	Thromboembolism	20%
51	Thrombosis	20%
52	Essential Hypertension	20%
53	Aneurysm, Ruptured	20%
54	Iliac Aneurysm	20%
55	Malignant Atrophic Papulosis	20%
56	Pulmonary artery stenosis	20%
57	White Coat Hypertension	20%
58	Systemic Vasculitis	20%
59	Embolus	20%
60	Shwartzman Phenomenon	19.8%
61	Coronary Aneurysm	19.7%
62	Aortic Aneurysm, Abdominal	19.6%
63	Aortic Aneurysm, Thoracic	19.6%
64	Heart Diseases	18.5%
65	Aortic Rupture	17.9%
66	Coronary heart disease	17.8%
67	Myocardial Infarction	17.8%
68	Acute Coronary Syndrome	17.8%
69	Myocardial Reperfusion Injury	17.7%
70	Intracranial Embolism and Thrombosis	17.2%
71	Carotid Stenosis	17.1%
72	Intracranial Aneurysm	17.1%
73	Coronary Thrombosis	17.1%
74	Coronary Artery Disease	17.1%
75	Carotid Artery Thrombosis	16.5%
76	Hand-Arm Vibration Syndrome	16.1%
77	Optic Neuropathy, Ischemic	15.5%
78	Anterior Ischemic Optic Neuropathy	15.5%
79	Mesenteric vascular insufficiency	15.5%
80	Moyamoya Disease	15.3%
81	Angioedema	15%
82	Lemierre Syndrome	15%
83	Colitis, Ischemic	14.9%
84	Arteriosclerosis Obliterans	14.8%
85	Atherosclerosis	14.8%
86	Air Embolism	14.8%
87	Endarteritis	14.8%
88	Polyarteritis Nodosa	14.8%
89	Takayasu Arteritis	14.8%
90	Venous Thrombosis	14.8%
91	Deep Vein Thrombosis	14.8%
92	Venous Thromboembolism	14.8%
93	Intracranial Arteriosclerosis	14.6%
94	Cerebral Atherosclerosis	14.6%
95	Cerebral Arteriosclerosis	14.6%
96	Arteriovenous fistula	14%
97	Retinal Artery Occlusion	13.6%
98	Retinal Vasculitis	13.6%
99	Hypertensive Retinopathy	13.6%
100	Kounis Syndrome	13.6%
101	Vasculitis, Central Nervous System	13.4%
102	Anterior Compartment Syndrome	13.3%
103	Vasculitis, Leukocytoclastic, Cutaneous	13.3%
104	Gastric Antral Vascular Ectasia	13.3%
105	Abdominal Compartment Syndrome	13.3%
106	Cerebral Thrombosis	13.3%
107	Intracranial Embolism	13.3%
108	Intracranial Thrombosis	13.3%
109	Carotid Artery Diseases	13.2%
110	Brain Ischemia	13.2%
111	Hypotension, Orthostatic	13.2%
112	Cerebrovascular accident	13.2%
113	Varicose Ulcer	13.2%
114	Vasospasm, Intracranial	13.2%
115	Spinal Cord Ischemia	13.2%
116	Intracranial Arterial Diseases	13.2%
117	Primary Graft Dysfunction	13.2%
118	Post-Exercise Hypotension	13.2%
119	Angina Pectoris	13.2%
120	Coronary Occlusion	13%
121	Microvascular Angina	13%
122	Coronary Stenosis	13%
123	ST segment elevation myocardial infarction	13%
124	Embolism, Amniotic Fluid	12.6%
125	Pregnancy Complications, Cardiovascular	12.2%
126	Cardiovascular Abnormalities	12.2%
127	Brain Infarction	11.6%
128	Sinus Thrombosis, Intracranial	11.4%
129	Giant Cell Arteritis	11%
130	Temporal Arteritis	11%
131	Coronary Restenosis	10.8%
132	Scimitar Syndrome	10.7%
133	Cavernous Sinus Thrombosis	10.5%
134	Sagittal Sinus Thrombosis	10.5%
135	Cardiac Tamponade	10.3%
136	Endocarditis	10.3%
137	Cardiac Arrest	10.3%
138	Heart failure	10.3%
139	Pericardial effusion	10.3%
140	Pericarditis	10.3%
141	Pneumopericardium	10.3%
142	Cor pulmonale	10.3%
143	Ventricular Outflow Obstruction	10.3%
144	Ventricular Dysfunction	10.3%
145	Cardiomyopathies	10.3%
146	Pleuropericarditis	10.3%
147	Mesenteric Vascular Occlusion	10.2%
148	Mucocutaneous Lymph Node Syndrome	10.2%
149	Intermittent Claudication	10.1%
150	Pulmonary Embolism	10.1%
151	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	10.1%
152	Diabetic Retinopathy	10.1%
153	Sturge-Weber Syndrome	10.1%
154	Renal hypertension	9.9%
155	Renal Artery Obstruction	9.9%
156	Renal Artery Stenosis	9.9%
157	No-Reflow Phenomenon	9.9%
158	Hemangioma, Cavernous	9.8%
159	Shock, Cardiogenic	9.8%
160	Basal Ganglia Cerebrovascular Disease	9.8%
161	Vertebral Artery Dissection	9.8%
162	Vascular Headaches	9.8%
163	Scurvy	9.8%
164	Cerebral Arterial Diseases	9.7%
165	Vertebrobasilar Insufficiency	9.7%
166	Anterior Spinal Artery Syndrome	9.7%
167	Basilar Artery Stenosis	9.7%
168	Vertebral Artery Stenosis	9.7%
169	Intracranial Hemorrhage, Hypertensive	9.7%
170	Transient Cerebral Ischemia	9.7%
171	Angina, Unstable	9.7%
172	Subarachnoid Hemorrhage, Traumatic	9.6%
173	Carotid Artery, Internal, Dissection	9.6%
174	Cerebral Infarction	9.6%
175	Brain Stem Infarctions	9.6%
176	Infarction, Middle Cerebral Artery	9.5%
177	Infarction, Anterior Cerebral Artery	9.5%
178	Infarction, Posterior Cerebral Artery	9.5%
179	Aortic Valve Stenosis	8.9%
180	Cardiomyopathy, Dilated	8.9%
181	Pulmonary Valve Stenosis	8.9%
182	Lateral Medullary Syndrome	8.6%
183	Hepatic Vein Thrombosis	8.4%
184	Budd-Chiari Syndrome	8.4%
185	Carotid Artery Injuries	8.4%
186	Pulmonary Infarction	8.2%
187	Subclavian Steal Syndrome	8%
188	Angina Pectoris, Variant	8%
189	Ischemic contracture	8%
190	Angioedemas, Hereditary	7.9%
191	Tricuspid Atresia	7.9%
192	Arrhythmogenic Right Ventricular Dysplasia	7.9%
193	Cryoglobulinemia	7.9%
194	Leukomalacia, Periventricular	7.9%
195	Diabetic Foot	7.8%
196	Basal Ganglia Hemorrhage	7.5%
197	Hypertension, Renovascular	7.3%
198	Subarachnoid Hemorrhage	7.3%
199	Hypoxia-Ischemia, Brain	7.3%
200	Cerebral Hemorrhage	7.3%
201	Hereditary Angioedema Type III	7.2%
202	Hereditary Angioedema Types I and II	7.2%
203	Hypertrophic Cardiomyopathy	7.1%
204	Hypertrophic obstructive cardiomyopathy	7.1%
205	Cardiac Output, High	7%
206	Myocardial Stunning	7%
207	Low Cardiac Output Syndrome	7%
208	Bacterial Endocarditis	6.8%
209	Cardiomegaly	6.8%
210	Postpericardiotomy Syndrome	6.8%
211	Cardiac Hypertrophy	6.8%
212	Rheumatic Heart Disease	6.7%
213	Aortic Valve Insufficiency	6.7%
214	Restrictive cardiomyopathy	6.7%
215	Endocardial Fibroelastosis	6.7%
216	Heart Block	6.7%
217	Heart Rupture, Post-Infarction	6.7%
218	Mitral Valve Insufficiency	6.7%
219	Mitral Valve Stenosis	6.7%
220	Myocarditis	6.7%
221	Pericarditis, Constrictive	6.7%
222	Pulmonary Valve Insufficiency	6.7%
223	Tachycardia	6.7%
224	Tricuspid Valve Insufficiency	6.7%
225	Tricuspid Valve Stenosis	6.7%
226	Tachyarrhythmia	6.7%
227	Ventricular Dysfunction, Left	6.7%
228	Right Ventricular Dysfunction	6.7%
229	Endomyocardial Fibrosis	6.7%
230	Carditis	6.7%
231	Heart Failure, Systolic	6.7%
232	Heart Failure, Diastolic	6.7%
233	Aortic coarctation	6.6%
234	Cor Triatriatum	6.6%
235	Coronary Vessel Anomalies	6.6%
236	Patent ductus arteriosus	6.6%
237	Ebstein Anomaly	6.6%
238	Heart Septal Defects	6.6%
239	Tetralogy of Fallot	6.6%
240	Transposition of Great Vessels	6.6%
241	Hypoplastic Left Heart Syndrome	6.6%
242	Shy-Drager Syndrome	6.5%
243	Supravalvular aortic stenosis	6.5%
244	Lown-Ganong-Levine Syndrome	6.5%
245	Purpura, Hyperglobulinemic	6.5%
246	Putaminal Hemorrhage	6.5%
247	Granulomatosis with polyangiitis	6.2%
248	Dementia, Vascular	6.1%
249	Cerebral Amyloid Angiopathy	6%
250	Pituitary Apoplexy	5.9%
251	Behcet Syndrome	5.7%
252	Waldenstrom Macroglobulinemia	5.7%
253	Multiple Myeloma	5.7%
254	CREST Syndrome	5.6%
255	Dextrocardia	5.3%
256	Long QT Syndrome	5.3%
257	Ataxia Telangiectasia	5.1%
258	Pseudoxanthoma Elasticum	5%
259	Aortic Valve Prolapse	4.9%
260	Tricuspid Valve Prolapse	4.9%
261	Rheumatoid Vasculitis	4.9%
262	Takotsubo Cardiomyopathy	4.9%
263	Adams-Stokes Syndrome	4.9%
264	Atrioventricular Block	4.9%
265	Bundle-Branch Block	4.9%
266	Atrial Premature Complexes	4.9%
267	Sinoatrial Block	4.9%
268	Tachycardia, Paroxysmal	4.9%
269	Supraventricular tachycardia	4.9%
270	Tachycardia, Ventricular	4.9%
271	Wolff-Parkinson-White Syndrome	4.9%
272	Tachycardia, Reciprocating	4.9%
273	Lupus Vasculitis, Central Nervous System	4.9%
274	Sick Sinus Syndrome	4.9%
275	Aortopulmonary Septal Defect	4.9%
276	Double Outlet Right Ventricle	4.9%
277	Endocardial Cushion Defects	4.9%
278	Myocardial bridging	4.9%
279	Aorticopulmonary Septal Defect	4.9%
280	Sinus Arrhythmia	4.4%
281	Atrial Fibrillation	4.4%
282	Atrial Flutter	4.4%
283	Edema, Cardiac	4.4%
284	Ventricular Fibrillation	4.4%
285	Ventricular Flutter	4.4%
286	Parasystole	4.4%
287	Paroxysmal atrial fibrillation	4.4%
288	Bradycardia	4.4%
289	Diabetic Cardiomyopathies	4.4%
290	Cardiomyopathy, Alcoholic	4.4%
291	Ectopia Cordis	4.4%
292	Sudden Cardiac Death	4.4%
293	Left Ventricular Hypertrophy	4.4%
294	Right Ventricular Hypertrophy	4.4%
295	Single umbilical artery	4.4%
296	Chagas Cardiomyopathy	4.4%
297	Tachycardia, Atrioventricular Nodal Reentry	4%
298	Tachycardia, Ectopic Atrial	4%
299	Tachycardia, Ectopic Junctional	4%
300	Sinus Tachycardia	4%
301	Torsades de Pointes	4%
302	Accelerated Idioventricular Rhythm	4%
303	Truncus Arteriosus, Persistent	4%
304	Carcinoid Heart Disease	3.9%
305	Romano-Ward Syndrome	3.9%
306	Subacute Bacterial Endocarditis	3.8%
307	Noonan Syndrome	3.8%
308	Hematoma, Subdural	3.5%
309	Hematoma, Epidural, Cranial	3.5%
310	Marfan Syndrome	3.4%
311	Dyspnea, Paroxysmal	3.3%
312	Sinus Arrest, Cardiac	3.3%
313	Hematoma, Subdural, Intracranial	3.1%
314	Hematoma, Subdural, Chronic	3.1%
315	Hematoma, Subdural, Acute	3.1%
316	Brain Hemorrhage, Traumatic	3%
317	MELAS Syndrome	2.9%
318	Dural Arteriovenous Fistula	2.7%
319	Fabry Disease	2.2%
320	Turner Syndrome	1.8%
321	Williams Syndrome	1.6%
322	Kartagener Syndrome	1.5%
323	Kearns-Sayre syndrome	1.2%

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