MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Supratentorial Neoplasms

(UMLS:C0038874)

Definition:: Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
UMLS ID:: C0038874
MeSH ID:: D015173

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.588.614.250.195.885

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.211.885|C10.551.240.250.700

Synonym(s)

Supratentorial Neoplasms

Brain Neoplasms, Supratentorial

Supratentorial Neoplasm

Supratentorial Tumor

Supratentorial Tumors

Supratentorial neoplasm

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Carboplatin	11902299 12837982	CTD
2	Cyclophosphamide	12837982	CTD
3	Thiotepa	12837982	CTD
4	Vincristine	12837982	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cerebellar Neoplasms	39.8%
2	Brain Stem Neoplasms	37.8%
3	Spinal Cord Neoplasms	31.7%
4	Choroid Plexus Papilloma	31.4%
5	Meningeal Neoplasms	30.1%
6	Central Nervous System Cysts	26.6%
7	Meningoencephalitis	22.3%
8	Encephalomyelitis	21.1%
9	Subdural Effusion	20.7%
10	Multiple System Atrophy	20.7%
11	Meningeal Carcinomatosis	19.9%
12	Dandy-Walker Syndrome	19.7%
13	Akinetic Mutism	19.4%
14	Anoxic Encephalopathy	19.4%
15	Basal Ganglia Diseases	19.4%
16	Brain Damage, Chronic	19.4%
17	Cerebellar Diseases	19.4%
18	Encephalitis	19.4%
19	Encephalomalacia	19.4%
20	Epilepsy	19.4%
21	Hydrocephalus	19.4%
22	Congenital Hydrocephalus	19.4%
23	Hypothalamic Diseases	19.4%
24	Thalamic Diseases	19.4%
25	Intracranial Hypertension	19.4%
26	Aura	19.4%
27	Leukoencephalopathy	19.4%
28	Neuroaxonal Dystrophies	19.4%
29	Headache Disorders	19.4%
30	Intracranial Hypotension	19.4%
31	Brain Edema	19.4%
32	Brain Hypoxia	19.4%
33	Aqueductal Stenosis	19.4%
34	Lewy Body Disease	18.8%
35	Pneumocephalus	18.6%
36	Dementia, Vascular	18.6%
37	Parkinsonian Disorders	18.1%
38	Posterior Leukoencephalopathy Syndrome	17.9%
39	Posterior reversible encephalopathy syndrome	17.9%
40	Paraneoplastic Encephalomyelitis	17.8%
41	Limbic Encephalitis	17.4%
42	Ocular Motility Disorders	17.3%
43	Cyclophoria	17.3%
44	Basal Ganglia Cerebrovascular Disease	17.3%
45	Marchiafava-Bignami Disease	17%
46	Brain Abscess	16.9%
47	Meningioma	16.7%
48	Epilepsy, Post-Traumatic	16.6%
49	Meningitis	16.5%
50	Movement Disorders	16.5%
51	Pachymeningitis	16.5%
52	Spinal Cord Diseases	16.5%
53	Brain Injuries	16.3%
54	Parkinson Disease	16.3%
55	Paraneoplastic Cerebellar Degeneration	16.2%
56	Brain Diseases, Metabolic	15.8%
57	Cerebrovascular Disorders	15.8%
58	Cerebrovascular Insufficiency	15.8%
59	Dementia	15.8%
60	Myelitis	15.6%
61	Meige Syndrome	15.4%
62	Cerebral Ventriculitis	15.4%
63	Myoclonic Epilepsy	15.3%
64	Epilepsy, Temporal Lobe	15.3%
65	Epilepsy, Rolandic	15.3%
66	Benign Rolandic Epilepsy	15.3%
67	Cranial nerve diseases	15.3%
68	Demyelinating Diseases	15.3%
69	Demyelination	15.3%
70	Neuromuscular Diseases	15.3%
71	Chronobiology Disorders	15.3%
72	Stiff-Person Syndrome	15.3%
73	Vascular Headaches	15.1%
74	Hypoxia-Ischemia, Brain	15%
75	Leukomalacia, Periventricular	14.8%
76	Epidural Abscess	14.8%
77	Prion Diseases	14.5%
78	Huntington Disease	14.3%
79	Brain Death	14.3%
80	Neuroleptic Malignant Syndrome	14.2%
81	Myelinolysis, Central Pontine	14.2%
82	Myelitis, Transverse	13.9%
83	Dystonia Musculorum Deformans	13.9%
84	Striatonigral Degeneration	13.8%
85	Central Nervous System Infection	13.7%
86	Progressive supranuclear palsy	13.6%
87	Opsoclonus-Myoclonus Syndrome	13.5%
88	Motor Neuron Disease	13.4%
89	Subacute Combined Degeneration	13.3%
90	Leukoencephalopathy, Progressive Multifocal	13.2%
91	Amblyopia	13.1%
92	Spinal Muscular Atrophy	13.1%
93	Progressive Muscular Atrophy	13.1%
94	Creutzfeldt-Jakob disease	12.9%
95	Cerebral Palsy	12.9%
96	Epilepsies, Partial	12.9%
97	Epilepsy, Generalized	12.9%
98	Pseudotumor Cerebri	12.9%
99	Hypertensive Encephalopathy	12.9%
100	Simple Partial Seizures	12.9%
101	Epilepsy, Reflex	12.9%
102	Headache Disorders, Primary	12.9%
103	Headache Disorders, Secondary	12.9%
104	Medication overuse headache	12.9%
105	Lambert-Eaton Myasthenic Syndrome	12.8%
106	Juvenile Myoclonic Epilepsy	12.7%
107	Myoclonic Epilepsies, Progressive	12.7%
108	Trauma, Nervous System	12.7%
109	Spinal Cord Injuries	12.5%
110	Ophthalmoplegic Migraine	12.5%
111	Neurologic Manifestations	12.4%
112	Neurotoxicity Syndromes	12.4%
113	Leukoencephalitis, Acute Hemorrhagic	12.3%
114	Amyotrophic Lateral Sclerosis	12.3%
115	Shy-Drager Syndrome	12.1%
116	Poliomyelitis	12.1%
117	Asterixis	12.1%
118	Ballismus	12.1%
119	MPTP Poisoning	12.1%
120	Basal Ganglia Hemorrhage	12%
121	Lupus Vasculitis, Central Nervous System	12%
122	Presenile dementia	11.9%
123	Senile dementia	11.9%
124	Restless Legs Syndrome	11.7%
125	Polyradiculoneuropathy	11.4%
126	Polyradiculoneuritis	11.4%
127	Pituitary Apoplexy	11.1%
128	Abdominal Neoplasms	11.1%
129	Encephalomyelitis, Acute Disseminated	11.1%
130	Head and Neck Neoplasms	11.1%
131	Soft Tissue Neoplasms	11.1%
132	Thoracic Neoplasms	11.1%
133	Lafora Disease	11%
134	Unverricht-Lundborg Syndrome	11%
135	Brain Infarction	11%
136	Brain Hemorrhage, Traumatic	10.9%
137	Amnesia, Transient Global	10.9%
138	Meningitis, Bacterial	10.8%
139	Meningitis, Fungal	10.8%
140	Chronic Fatigue Syndrome	10.8%
141	Miller Fisher Syndrome	10.8%
142	Pituitary Diseases	10.8%
143	Carotid Artery Injuries	10.8%
144	Brain Injuries, Diffuse	10.7%
145	Traumatic Brain Injury	10.7%
146	Hepatolenticular Degeneration	10.7%
147	Vasculitis, Central Nervous System	10.7%
148	Cerebellar Ataxia	10.7%
149	Autonomic Dysreflexia	10.6%
150	Complex Regional Pain Syndromes	10.6%
151	Sleep Wake Disorders	10.5%
152	Carotid Artery Diseases	10.4%
153	Brain Ischemia	10.4%
154	Cerebrovascular accident	10.4%
155	Kluver-Bucy Syndrome	10.4%
156	Vasospasm, Intracranial	10.4%
157	Intracranial Arterial Diseases	10.4%
158	Putaminal Hemorrhage	10.2%
159	Persistent Vegetative State	10.1%
160	Pituitary Adenoma	10.1%
161	Pituitary Neoplasms	10.1%
162	Canavan Disease	10%
163	Alexander Disease	10%
164	Infarction, Middle Cerebral Artery	9.9%
165	Infarction, Anterior Cerebral Artery	9.9%
166	Infarction, Posterior Cerebral Artery	9.9%
167	Arachnoiditis	9.7%
168	Aseptic Meningitis	9.7%
169	Syringomyelia	9.7%
170	Essential Tremor	9.7%
171	Familial Tremor	9.7%
172	Pneumorrhachis	9.7%
173	Writer's Cramp	9.7%
174	Toxoplasmosis, Cerebral	9.7%
175	Friedreich Ataxia	9.7%
176	Post-Traumatic Headache	9.6%
177	Tension Headache	9.6%
178	Epilepsy, Complex Partial	9.6%
179	Migraine Disorders	9.6%
180	Abdominal Migraine	9.6%
181	Status Migrainosus	9.6%
182	Cervicogenic Headache	9.6%
183	Tuberous Sclerosis	9.4%
184	Digestive System Neoplasms	9.3%
185	Endocrine Gland Neoplasms	9.3%
186	Eye Neoplasms	9.3%
187	Akathisia, Drug-Induced	9.1%
188	Cerebral Infarction	9.1%
189	Brain Stem Infarctions	9.1%
190	Optic Nerve Glioma	9%
191	Bone neoplasms	9%
192	Skin Neoplasms	9%
193	Hematologic Neoplasms	9%
194	Peripheral Nerve Injuries	8.9%
195	Splenic Neoplasms	8.9%
196	Dyskinesia, Drug-Induced	8.8%
197	Moyamoya Disease	8.8%
198	Myasthenia Gravis	8.8%
199	Reye Syndrome	8.7%
200	Intracranial Embolism and Thrombosis	8.6%
201	Hepatic Encephalopathy	8.6%
202	Acoustic Neuroma	8.6%
203	Guillain-Barre Syndrome	8.5%
204	Dysautonomia	8.2%
205	Vagus Nerve Disorder	8.2%
206	Glossopharyngeal Neuralgia	8.2%
207	Abducens Nerve Diseases	8.2%
208	Heavy Metal Poisoning, Nervous System	8.2%
209	Neuromuscular Junction Diseases	8.2%
210	Tauopathies	8.2%
211	Trochlear Nerve Diseases	8.2%
212	Peripheral Nervous System Diseases	8.2%
213	Lateral Medullary Syndrome	8.2%
214	Mitochondrial Encephalomyopathies	8.1%
215	Tuberculosis, Meningeal	8%
216	Cluster Headache	8%
217	Migraine with Aura	8%
218	Familial Hemiplegic Migraine	8%
219	Chronic Paroxysmal Hemicrania	8%
220	SUNCT Syndrome	8%
221	Paroxysmal Hemicrania	8%
222	Diffuse Axonal Injury	8%
223	Central Nervous System Fungal Infections	7.9%
224	Conus Medullaris Syndrome	7.9%
225	Spinal Cord Vascular Diseases	7.9%
226	Empty Sella Syndrome	7.8%
227	Hyperpituitarism	7.8%
228	Hypopituitarism	7.8%
229	Hypophysitis	7.8%
230	Progressive bulbar palsy	7.8%
231	Bulbar palsy	7.8%
232	Sleep Disorders, Circadian Rhythm	7.8%
233	Cerebral Arterial Diseases	7.7%
234	Vertebrobasilar Insufficiency	7.7%
235	Basilar Artery Stenosis	7.7%
236	Vertebral Artery Stenosis	7.7%
237	Intracranial Hemorrhage, Hypertensive	7.7%
238	Transient Cerebral Ischemia	7.7%
239	Scrapie	7.7%
240	Central Cord Syndrome	7.7%
241	Subarachnoid Hemorrhage, Traumatic	7.7%
242	Carotid Artery, Internal, Dissection	7.7%
243	Causalgia	7.5%
244	Chorea	7.5%
245	Botulism	7.5%
246	Ataxia Telangiectasia	7.5%
247	Brain Diseases, Metabolic, Inborn	7.5%
248	Olfactory Nerve Injuries	7.4%
249	Frontotemporal dementia	7.3%
250	Vertebral Artery Dissection	7.3%
251	Adrenoleukodystrophy	7.3%
252	Hamartoma	7.2%
253	Neoplasms, Hormone-Dependent	7.2%
254	Neoplasms, Multiple Primary	7.2%
255	Paraneoplastic Syndromes	7.2%
256	Precancerous Conditions	7.2%
257	Neoplasms, Second Primary	7.2%
258	MELAS Syndrome	7.2%
259	Auditory Perceptual Disorders	7.2%
260	Subacute Sclerosing Panencephalitis	7.2%
261	Parathyroid Neoplasms	7.2%
262	Peritoneal Neoplasms	7.2%
263	Thyroid Neoplasm	7.2%
264	Thyroid carcinoma	7.2%
265	Neuromyelitis Optica	7.1%
266	Multiple Endocrine Neoplasia	6.9%
267	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6.9%
268	Brain Contusion	6.9%
269	Myopathy	6.9%
270	Optic Neuropathy	6.9%
271	Brain Concussion	6.8%
272	Facial Nerve Diseases	6.7%
273	Craniocerebral Trauma	6.7%
274	Parasomnia	6.7%
275	Dyssomnias	6.7%
276	Central Nervous System Bacterial Infections	6.7%
277	neurofibroma	6.7%
278	Vestibulocochlear Nerve Diseases	6.6%
279	Decerebrate State	6.6%
280	Hemiparesis	6.6%
281	Hydranencephaly	6.6%
282	Meningism	6.6%
283	Neural Tube Defects	6.6%
284	Paresis	6.6%
285	Seizures	6.6%
286	Sensation Disorders	6.6%
287	Tethered Cord Syndrome	6.6%
288	Complex partial seizures	6.6%
289	Iniencephaly	6.6%
290	Craniorachischisis	6.6%
291	Exencephaly	6.6%
292	Monoparesis	6.6%
293	Septo-Optic Dysplasia	6.6%
294	Cortical Dysplasia	6.6%
295	Neurogenic Inflammation	6.6%
296	Gait Disorders, Neurologic	6.6%
297	Neuromuscular Manifestations	6.6%
298	Malformations of Cortical Development	6.6%
299	Mammary Neoplasms, Experimental	6.6%
300	Sweating, Gustatory	6.6%
301	Auriculotemporal Syndrome	6.6%
302	Horner Syndrome	6.5%
303	Facial Nerve Injuries	6.5%
304	Multiple Sclerosis	6.5%
305	Wernicke Encephalopathy	6.5%
306	AIDS Dementia Complex	6.5%
307	Reflex Sympathetic Dystrophy	6.5%
308	Nocturnal Myoclonus Syndrome	6.5%
309	Prolactinoma	6.5%
310	Growth Hormone-Secreting Pituitary Adenoma	6.5%
311	Carotid Stenosis	6.5%
312	Intracranial Aneurysm	6.5%
313	Meningitis, Cryptococcal	6.5%
314	Hyperprolactinemia	6.4%
315	Alice in Wonderland Syndrome	6.4%
316	Meningitis, Listeria	6.4%
317	Intracranial Arteriosclerosis	6.4%
318	Cerebral Atherosclerosis	6.4%
319	Subarachnoid Hemorrhage	6.4%
320	Torticollis	6.4%
321	Cerebral Arteriosclerosis	6.4%
322	Cerebral Hemorrhage	6.4%
323	Meningitis, Haemophilus	6.4%
324	Meningitis, Pneumococcal	6.4%
325	Cerebral Thrombosis	6.4%
326	Intracranial Embolism	6.4%
327	Intracranial Thrombosis	6.4%
328	Subclavian Steal Syndrome	6.4%
329	Pick Disease of the Brain	6.4%
330	Pancreatic Neoplasm	6.3%
331	Sturge-Weber Syndrome	6.3%
332	Nervous System Neoplasms	6.2%
333	Retroperitoneal Neoplasms	6.1%
334	Kernicterus	5.9%
335	Cyst	5.8%
336	Neoplastic Processes	5.8%
337	Neoplastic Syndromes, Hereditary	5.8%
338	Pregnancy Complications, Neoplastic	5.8%
339	Giant Cell Arteritis	5.8%
340	Acanthoma	5.8%
341	Temporal Arteritis	5.8%
342	Myasthenia Gravis, Autoimmune, Experimental	5.8%
343	Neoplasms, Experimental	5.8%
344	Refsum Disease	5.8%
345	Jet Lag Syndrome	5.7%
346	Tracheal Neoplasms	5.7%
347	Pupil Disorders	5.7%
348	Neurobehavioral Manifestations	5.7%
349	Ophthalmoplegia	5.6%
350	External Ophthalmoplegia	5.6%
351	West Nile Fever	5.6%
352	Uveomeningoencephalitic Syndrome	5.5%
353	Carotid Artery Thrombosis	5.5%
354	Nelson Syndrome	5.5%
355	Vertigo	5.5%
356	Alcohol-Induced Disorders, Nervous System	5.5%
357	Acromegaly	5.4%
358	Acrodynia	5.4%
359	Tardive Dyskinesia	5.3%
360	Cerebral Amyloid Angiopathy	5.3%
361	Sinus Thrombosis, Intracranial	5.3%
362	Charcot-Marie-Tooth Disease	5.2%
363	Spinal Cord Ischemia	5.2%
364	Brachial Plexus Neuritis	5.1%
365	Neuralgic Amyotrophy	5.1%
366	Tuberculosis, Central Nervous System	5.1%
367	Vocal Cord Paralysis	5%
368	Hematoma, Subdural	5%
369	Hematoma, Epidural, Cranial	5%
370	Mouth Neoplasms	5%
371	Vascular Neoplasms	5%
372	Thymus Neoplasms	5%
373	Esophageal Neoplasms	4.9%
374	Genital Neoplasms, Female	4.9%
375	Neuritis	4.9%
376	Polyneuritis	4.9%
377	Radiculitis	4.9%
378	Polyneuropathy	4.9%
379	Mononeuritis	4.9%
380	Mononeuropathies	4.9%
381	Brachial Plexus Neuropathies	4.9%
382	Radiculopathy	4.9%
383	Mononeuropathy Multiplex	4.9%
384	Nerve Root Compression	4.9%
385	Breast Neoplasms, Male	4.9%
386	Triple Negative Breast Neoplasms	4.9%
387	Voice Disorders	4.8%
388	Voice Disturbance	4.8%
389	Neoplasms, Radiation-Induced	4.8%
390	Cavernous Sinus Thrombosis	4.8%
391	Sagittal Sinus Thrombosis	4.8%
392	Smith-Magenis syndrome	4.7%
393	Dural Arteriovenous Fistula	4.7%
394	Myotonia Congenita	4.7%
395	Cerebrospinal Fluid Otorrhea	4.6%
396	Cerebrospinal Fluid Rhinorrhea	4.6%
397	Neuritis, Autoimmune, Experimental	4.6%
398	Carcinoma, Lobular	4.6%
399	Gait Ataxia	4.6%
400	Coma, Post-Head Injury	4.6%
401	Tarsal Tunnel Syndrome	4.5%
402	Cauda Equina Syndrome	4.5%
403	Neurofibrosarcoma	4.5%
404	Fabry Disease	4.5%
405	Testicular Neoplasms	4.4%
406	Neuroaspergillosis	4.3%
407	Alcohol Withdrawal Seizures	4.3%
408	Galactosemias	4.3%
409	Urea Cycle Disorders, Inborn	4.3%
410	Tyrosinemias	4.3%
411	Multiple Sclerosis, Chronic Progressive	4.3%
412	Multiple Sclerosis, Relapsing-Remitting	4.3%
413	Hematoma, Subdural, Intracranial	4.2%
414	Hematoma, Subdural, Chronic	4.2%
415	Hematoma, Subdural, Acute	4.2%
416	Myotonic Dystrophy	4.2%
417	Adrenal Gland Neoplasms	4.2%
418	Gastrointestinal Neoplasms	4.2%
419	Genital Neoplasms, Male	4.2%
420	Liver neoplasms	4.2%
421	Uveal Neoplasms	4.2%
422	Thyroid Nodule	4.2%
423	Urologic Neoplasms	4.1%
424	Brain Diseases	4.1%
425	Reflex, Abnormal	4.1%
426	Hyporeflexia	4.1%
427	Hyperreflexia	4.1%
428	Sebaceous Gland Neoplasms	4.1%
429	Spinal Neoplasms	4.1%
430	Bone Marrow Neoplasms	4.1%
431	Akathisia	4%
432	Restlessness	4%
433	Psychomotor Agitation	4%
434	Myositis	4%
435	Optic Atrophy	4%
436	Optic Neuritis	4%
437	Papilledema	4%
438	Strabismus	4%
439	Tolosa-Hunt Syndrome	4%
440	Isaacs syndrome	4%
441	Arsenic Poisoning	4%
442	Myotonic Disorders	4%
443	Myasthenic Syndromes, Congenital	4%
444	Carcinoma, Ehrlich Tumor	3.9%
445	Dermoid Cyst	3.9%
446	Carcinoma, Lewis Lung	3.9%
447	Diabetic Neuropathies	3.9%
448	Facial Injuries	3.9%
449	Facial Neuralgia	3.9%
450	Diabetic Amyotrophy	3.9%
451	Diabetic Autonomic Neuropathy	3.9%
452	Sleep Talking	3.9%
453	Manganese Poisoning	3.9%
454	Sleep Disorders, Intrinsic	3.9%
455	Orthostatic intolerance	3.9%
456	Anosmia	3.9%
457	Ataxia	3.9%
458	Athetosis	3.9%
459	Catalepsy	3.9%
460	Dystonia	3.9%
461	Hemiplegia	3.9%
462	Homocystinuria	3.9%
463	Locked-In Syndrome	3.9%
464	Meningomyelocele	3.9%
465	Muscle Hypertonia	3.9%
466	Muscle hypotonia	3.9%
467	Myoclonus	3.9%
468	Myotonia	3.9%
469	Neuralgia	3.9%
470	Paraplegia	3.9%
471	Pseudobulbar Palsy	3.9%
472	Quadriplegia	3.9%
473	Spasm	3.9%
474	Spastic Paraplegia	3.9%
475	Status Epilepticus	3.9%
476	Taste Disorders	3.9%
477	Tremor	3.9%
478	Spina Bifida	3.9%
479	Monoplegia	3.9%
480	Hypokinesia	3.9%
481	Paraparesis	3.9%
482	Bradykinesia	3.9%
483	Waxy flexibility	3.9%
484	Action Tremor	3.9%
485	Resting Tremor	3.9%
486	Dysosmia	3.9%
487	Quadriparesis	3.9%
488	Mercury Poisoning, Nervous System	3.9%
489	Olfaction Disorders	3.9%
490	Myokymia	3.9%
491	Lead Poisoning, Nervous System	3.9%
492	Vestibular Neuronitis	3.9%
493	Somatosensory Disorders	3.9%
494	Neuropathic pain	3.9%
495	Hyperkinesia	3.9%
496	Intention tremor	3.9%
497	Pseudorabies	3.9%
498	Multiple Endocrine Neoplasia Type 1	3.9%
499	Leigh Disease	3.9%
500	Trophoblastic Neoplasms	3.9%
501	Anterior Spinal Artery Syndrome	3.8%
502	Leukemia, Experimental	3.8%
503	Carcinoma 256, Walker	3.8%
504	Thymoma	3.8%
505	Carpal Tunnel Syndrome	3.8%
506	Sciatica	3.7%
507	Menkes Kinky Hair Syndrome	3.7%
508	Erythroplasia	3.7%
509	Follicular cyst	3.7%
510	leukemia	3.7%
511	Mucocele	3.7%
512	Neoplasms, Germ Cell and Embryonal	3.7%
513	Neoplasms, Glandular and Epithelial	3.7%
514	Pilonidal Cyst	3.7%
515	Thyroglossal Cyst	3.7%
516	Synovial Cyst	3.7%
517	Germ Cell Cancer	3.7%
518	Aberrant Crypt Foci	3.7%
519	Liver Neoplasms, Experimental	3.7%
520	Neurosyphilis	3.7%
521	Gait Apraxia	3.6%
522	Alstrom Syndrome	3.5%
523	Carcinoma, Pancreatic Ductal	3.5%
524	Hand-Arm Vibration Syndrome	3.4%
525	Vision Disorders	3.4%
526	Metamorphopsia	3.4%
527	Visual Impairment	3.4%
528	Fibromyalgia	3.3%
529	Optic Neuropathy, Ischemic	3.3%
530	Anterior Ischemic Optic Neuropathy	3.3%
531	Medial Tibial Stress Syndrome	3.3%
532	Leukemia, Radiation-Induced	3.3%
533	Facial Hemiatrophy	3.3%
534	Melkersson-Rosenthal Syndrome	3.3%
535	Mitochondrial Myopathies	3.3%
536	Central Nervous System Neoplasms	3.3%
537	Anisocoria	3.3%
538	Confusion	3.3%
539	Facial paralysis	3.3%
540	Lethargy	3.3%
541	Memory Disorders	3.3%
542	Muscle Cramp	3.3%
543	Perceptual Disorders	3.3%
544	Psychomotor Disorders	3.3%
545	Tonic Pupil	3.3%
546	Eosinophilia-Myalgia Syndrome	3.3%
547	Anhedonia	3.3%
548	Disorientation	3.3%
549	Facial Paresis	3.3%
550	Memory Loss	3.3%
551	Hemisensory Neglect	3.3%
552	Dysacusis	3.3%
553	Sarcoma, Experimental	3.3%
554	Sleep Bruxism	3.3%
555	Leukoplakia, Oral	3.3%
556	Toxoplasmosis, Congenital	3.3%
557	Neuroectodermal Tumors	3.3%
558	Anencephaly	3.3%
559	Brain Neoplasms	3.3%
560	Meningocele	3.3%
561	Muscular Atrophy	3.3%
562	Respiratory Paralysis	3.3%
563	Encephalocele	3.3%
564	Malaria, Cerebral	3.2%
565	Tetany	3.2%
566	Amyloid Neuropathies, Familial	3.2%
567	Neurocysticercosis	3.2%
568	Sciatic Neuropathy	3.2%
569	Ulnar Neuropathies	3.2%
570	Lesion of Sciatic Nerve	3.2%
571	Ulnar Neuritis	3.2%
572	Radial nerve compression	3.2%
573	Radial Tunnel Syndrome	3.2%
574	Peroneal Neuropathies	3.2%
575	Radial Neuropathy	3.2%
576	Median Neuropathy	3.2%
577	Sciatic Nerve Palsy	3.2%
578	Femoral Neuropathy	3.2%
579	Tibial Neuropathy	3.2%
580	Lyme Neuroborreliosis	3.2%
581	Ulnar Nerve Palsy	3.2%
582	Postural Orthostatic Tachycardia Syndrome	3.2%
583	Radial nerve palsy	3.2%
584	Cubital Tunnel Syndrome	3.2%
585	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.2%
586	ovarian neoplasm	3.1%
587	Melanoma, Experimental	3%
588	Nose Neoplasms	3%
589	Leukoplakia	3%
590	Lymphocele	3%
591	Pancreatic Cyst	3%
592	Zellweger Syndrome	3%
593	Barrett Esophagus	3%
594	Breast Cyst	3%
595	Histiocytic Disorders, Malignant	3%
596	Actinic keratosis	3%
597	Mediastinal Cyst	3%
598	Neoplasm Invasiveness	3%
599	Neoplasm Metastasis	3%
600	Neoplasm Recurrence, Local	3%
601	Parovarian Cyst	3%
602	Pericardial Cyst	3%
603	Thymic Cyst	3%
604	Carcinogenesis	3%
605	Myxoid cyst	3%
606	Metastasis	3%
607	Neoplasms, Neuroepithelial	3%
608	Gliomatosis cerebri	3%
609	Nephroblastoma	3%
610	Waterhouse-Friderichsen Syndrome	2.9%
611	Glycogen storage disease type II	2.9%
612	Duane Retraction Syndrome	2.9%
613	Consciousness Disorders	2.9%
614	Mental Retardation	2.9%
615	Muscle Weakness	2.9%
616	Depressed Level of Consciousness	2.9%
617	Mental deficiency	2.9%
618	Intellectual Disability	2.9%
619	Mobius Syndrome	2.8%
620	Bell Palsy	2.8%
621	Catatonia	2.8%
622	Herpes Zoster Oticus	2.8%
623	Familial Periodic Paralysis	2.8%
624	Aphonia	2.8%
625	Sleep Deprivation	2.8%
626	Dysphonia	2.8%
627	Classical Lissencephalies and Subcortical Band Heterotopias	2.8%
628	Hepatocellular Adenoma	2.8%
629	Palatal Neoplasms	2.7%
630	Thoracic Outlet Syndrome	2.6%
631	Retinoblastoma	2.6%
632	Carcinosarcoma	2.6%
633	Esotropia	2.6%
634	Exotropia	2.6%
635	Hemangiosarcoma	2.6%
636	Hypotension, Orthostatic	2.6%
637	Leukemia L1210	2.6%
638	Leukemia P388	2.6%
639	lymphangiosarcoma	2.6%
640	Sleep Apnea Syndromes	2.6%
641	Polymyositis	2.6%
642	Post-Exercise Hypotension	2.6%
643	Disorders of Excessive Somnolence	2.6%
644	Sleep Initiation and Maintenance Disorders	2.6%
645	Night Terrors	2.6%
646	Somnambulism	2.6%
647	Trigeminal Nerve Disorder	2.6%
648	Transient Insomnia	2.6%
649	Sleep Paralysis	2.6%
650	Chronic Insomnia	2.6%
651	REM Sleep Behavior Disorder	2.6%
652	Hypersomnia	2.6%
653	Dermal Sinus	2.6%
654	Dysgeusia	2.6%
655	Formication	2.6%
656	Hyperalgesia	2.6%
657	Hyperesthesia	2.6%
658	Hypesthesia	2.6%
659	Language Disorders	2.6%
660	Numbness	2.6%
661	Paresthesia	2.6%
662	Paraparesis, Spastic	2.6%
663	Spina Bifida Cystica	2.6%
664	Trismus	2.6%
665	Spina Bifida Occulta	2.6%
666	Epilepsia Partialis Continua	2.6%
667	Hypogeusia	2.6%
668	Brown-Sequard Syndrome	2.6%
669	Lissencephaly	2.6%
670	Polymicrogyria	2.6%
671	Pachygyria	2.6%
672	Schizencephaly	2.6%
673	Lockjaw	2.6%
674	Allodynia	2.6%
675	Lead Poisoning, Nervous System, Childhood	2.6%
676	Lead Poisoning, Nervous System, Adult	2.6%
677	Periventricular Nodular Heterotopia	2.6%
678	Ageusia	2.6%
679	Lymphomatoid Granulomatosis	2.5%
680	Ear Neoplasms	2.5%
681	Eyelid Neoplasms	2.5%
682	Lung Neoplasms	2.5%
683	Pleural Neoplasms	2.5%
684	insulinoma	2.5%
685	Lymphoma	2.5%
686	Corpus Luteum Cyst	2.5%
687	Ovarian Cysts	2.5%
688	Myalgia	2.4%
689	Salivary Gland Neoplasms	2.4%
690	Tongue Neoplasms	2.4%
691	Neuronal Ceroid-Lipofuscinoses	2.4%
692	melanoma	2.4%
693	Uterine Neoplasms	2.4%
694	Vaginal Neoplasms	2.4%
695	Vulvar Neoplasms	2.4%
696	Uterine Cancer	2.4%
697	Fallopian Tube Neoplasms	2.4%
698	Alexia	2.4%
699	Gastrinoma	2.4%
700	Glucagonoma	2.4%
701	Polyradiculopathy	2.4%
702	Dyslexia	2.4%
703	Vipoma	2.4%
704	Gaucher Disease	2.4%
705	Composite Lymphoma	2.3%
706	Choriocarcinoma	2.3%
707	Optic Atrophy, Hereditary, Leber	2.3%
708	Sarcoma 180	2.3%
709	Eye Injuries	2.2%
710	Kearns-Sayre syndrome	2.2%
711	Aicardi's syndrome	2.2%
712	Hoarseness	2.2%
713	Muscular Dystrophy	2.2%
714	Congenital nystagmus	2.2%
715	Orbital Myositis	2.2%
716	Cockayne Syndrome	2.2%
717	Alcohol Withdrawal Delirium	2.2%
718	Diplopia	2.2%
719	Muscle Rigidity	2.2%
720	Muscle Spasticity	2.2%
721	Scotoma	2.2%
722	Photophobia	2.2%
723	Cogwheel Rigidity	2.2%
724	Hemifacial Spasm	2.2%
725	Amaurosis	2.2%
726	Blindness	2.2%
727	Nuchal Rigidity	2.2%
728	Pyomyositis	2.2%
729	Tay-Sachs Disease	2.2%
730	Pharyngeal Neoplasms	2.2%
731	Leukemia, Plasma Cell	2.2%
732	Agnosia	2.2%
733	Apraxias	2.2%
734	Hallucinations	2.2%
735	Hemianopsia	2.2%
736	Hyperacusis	2.2%
737	Tinnitus	2.2%
738	Visual Agnosia	2.2%
739	Anosognosia	2.2%
740	Wernicke-Korsakoff Syndrome	2.2%
741	Phonophobia	2.2%
742	Hearing Loss	2.2%
743	Choledochal Cyst	2.1%
744	granulosa cell tumor	2.1%
745	Carcinoma, Ovarian Epithelial	2.1%
746	Supratentorial Neoplasms	2.1%
747	Sarcopenia	2.1%
748	Peutz-Jeghers Syndrome	2.1%
749	Bile Duct Neoplasms	2.1%
750	gallbladder neoplasm	2.1%
751	Intestinal Neoplasms	2.1%
752	Penile Neoplasms	2.1%
753	Prostatic Neoplasms	2.1%
754	Stomach Neoplasms	2.1%
755	Adenomatous Polyposis Coli	2.1%
756	Polycythemia Vera	2.1%
757	Niemann-Pick Disease, Type C	2.1%
758	Basal Cell Nevus Syndrome	2%
759	Adenoma	2%
760	Ameloblastoma	2%
761	Angiokeratoma	2%
762	Carcinoma	2%
763	Chordoma	2%
764	Hemangioma	2%
765	hemangiopericytoma	2%
766	Lymphangioma	2%
767	Mesenchymoma	2%
768	Nevus	2%
769	Teratoma	2%
770	Hepatoblastoma	2%
771	Mixed Tumor, Mullerian	2%
772	Germinoma	2%
773	Teratocarcinoma	2%
774	Angiofibroma	2%
775	Sarcoma	2%
776	Epithelioma	2%
777	Leydig Cell Tumor	2%
778	Mesoblastic Nephroma	2%
779	Holoprosencephaly	2%
780	Basal cell carcinoma	1.9%
781	Carcinoma, Papillary	1.9%
782	Squamous cell carcinoma	1.9%
783	Chondrosarcoma	1.9%
784	Craniopharyngioma	1.9%
785	Cystadenoma	1.9%
786	leiomyosarcoma	1.9%
787	liposarcoma	1.9%
788	Mesothelioma	1.9%
789	synovial sarcoma	1.9%
790	Neuroectodermal Tumor, Melanotic	1.9%
791	Angiomyolipoma	1.9%
792	Clear Cell Sarcoma of Soft Tissue	1.9%
793	Alveolar Soft Part Sarcoma	1.9%
794	Neuroendocrine Tumors	1.9%
795	Sarcoma, Myeloid	1.9%
796	Carcinoma, Basal Cell	1.9%
797	Sleep Apnea, Obstructive	1.9%
798	Sleep Apnea, Central	1.9%
799	Narcolepsy	1.9%
800	Trigeminal Neuralgia	1.9%
801	Kleine-Levin Syndrome	1.9%
802	Agraphia	1.9%
803	Anomia	1.9%
804	Cluttering	1.9%
805	Language Development Disorders	1.9%
806	Speech Disorders	1.9%
807	Syncope	1.9%
808	Stupor	1.9%
809	Dysgraphia	1.9%
810	Presyncope	1.9%
811	Dyslalia	1.9%
812	Laryngeal neoplasm	1.9%
813	Amnesia	1.9%
814	Delirium	1.9%
815	Dissociative Amnesia	1.9%
816	Color blindness	1.9%
817	Global Amnesia	1.9%
818	Adenoma, Acidophil	1.9%
819	Ganglioneuroma	1.9%
820	Glioma	1.9%
821	Malignant Glioma	1.9%
822	Cri-du-Chat Syndrome	1.9%
823	Down Syndrome	1.9%
824	Trisomy 21	1.9%
825	POEMS Syndrome	1.9%
826	Williams Syndrome	1.9%
827	Microcephaly	1.8%
828	Macrocephaly	1.8%
829	Hypokalemic periodic paralysis	1.8%
830	Porencephaly	1.8%
831	Bladder Neoplasm	1.8%
832	Kidney Neoplasm	1.8%
833	Ureteral Neoplasms	1.8%
834	Urethral Neoplasms	1.8%
835	Medulloblastoma	1.8%
836	Bronchial Neoplasms	1.6%
837	Prader-Willi Syndrome	1.6%
838	Pancreatic Pseudocyst	1.6%
839	Plasmacytoma	1.6%
840	Eye Burns	1.6%
841	Multiple Pulmonary Nodules	1.6%
842	Malignant histiocytosis	1.6%
843	Lymphatic Metastasis	1.6%
844	Neoplasms, Unknown Primary	1.6%
845	Leukemic Infiltration	1.6%
846	Histiocytic sarcoma	1.6%
847	Neoplasm Micrometastasis	1.6%
848	Welander Distal Myopathy	1.6%
849	Phantom pain	1.6%
850	Phantom Limb Pain	1.6%
851	Amaurosis Fugax	1.6%
852	Blindness, Cortical	1.6%
853	Dyscalculia	1.6%
854	Rett Syndrome	1.6%
855	Adrenocortical carcinoma	1.6%
856	Cystadenocarcinoma	1.6%
857	Fibrosarcoma	1.6%
858	Osteosarcoma	1.6%
859	Mucoepidermoid Carcinoma	1.6%
860	Endometrial Stromal Sarcoma	1.6%
861	Deafness	1.6%
862	Hearing Loss, Sudden	1.6%
863	Gerstmann Syndrome	1.6%
864	Hearing Loss, Bilateral	1.6%
865	Hearing Loss, High-Frequency	1.6%
866	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
867	Prosopagnosia	1.6%
868	Apraxia, Ideomotor	1.6%
869	Charles Bonnet Syndrome	1.6%
870	Hearing Loss, Unilateral	1.6%
871	Complete Hearing Loss	1.6%
872	Alien Hand Syndrome	1.6%
873	Deaf Mutism	1.6%
874	Carcinoid Tumor	1.6%
875	Endometrial Neoplasms	1.6%
876	Neurilemmoma	1.6%
877	Hutchinson's Melanotic Freckle	1.6%
878	Melanoma, Amelanotic	1.6%
879	Cataplexy	1.6%
880	Aphasia	1.6%
881	Articulation Disorders	1.6%
882	Echolalia	1.6%
883	Stuttering	1.6%
884	Dysphasia	1.6%
885	Adenofibroma	1.4%
886	Fibroadenoma	1.4%
887	Malignant Fibrous Histiocytoma	1.4%
888	Dysarthria	1.4%
889	Renal Cell Carcinoma	1.4%
890	Papillary Renal Cell Carcinoma	1.4%
891	Dermatomyositis	1.4%
892	Corneal Scar	1.4%
893	Hypopharyngeal Neoplasms	1.4%
894	Pleural Effusion, Malignant	1.4%
895	Hypopharyngeal Cancer	1.4%
896	Muscular Dystrophy, Duchenne	1.4%
897	Lymphangioleiomyomatosis	1.4%
898	Retrograde amnesia	1.4%
899	Amnesia, Anterograde	1.4%
900	Parotid Neoplasms	1.4%
901	Prostatic Neoplasms, Castration-Resistant	1.4%
902	Xeroderma Pigmentosum	1.4%
903	Mutism	1.4%
904	Selective Mutism	1.4%
905	Hodgkin Disease	1.3%
906	Lymphoma, Non-Hodgkin	1.3%
907	Polycystic Ovary Syndrome	1.3%
908	Hydatidiform Mole	1.3%
909	Denys-Drash Syndrome	1.3%
910	Astrocytoma	1.3%
911	Ependymoma	1.3%
912	oligodendroglioma	1.3%
913	Ganglioglioma	1.3%
914	gliosarcoma	1.3%
915	Anaplastic astrocytoma	1.3%
916	Anaplastic Oligodendroglioma	1.3%
917	Rubinstein-Taybi Syndrome	1.3%
918	Bowen's Disease	1.3%
919	Paraganglioma	1.3%
920	Rhabdomyosarcoma	1.3%
921	Giant Cell Tumor of Bone	1.3%
922	Adenocarcinoma	1.2%
923	Carcinoma in Situ	1.2%
924	Carcinoma, Transitional Cell	1.2%
925	Cecal Neoplasms	1.2%
926	Phyllodes Tumor	1.2%
927	Duodenal Neoplasms	1.2%
928	Dysgerminoma	1.2%
929	Fragile X Syndrome	1.2%
930	Hemangioendothelioma	1.2%
931	Lipoma	1.2%
932	Myoma	1.2%
933	Myxoma	1.2%
934	Neuroma	1.2%
935	Papilloma	1.2%
936	Pseudomyxoma Peritonei	1.2%
937	Seminoma	1.2%
938	Papillomatosis	1.2%
939	Angiolipoma	1.2%
940	Myelolipoma	1.2%
941	Neoplasms, Bone Tissue	1.2%
942	Neoplasms, Fibrous Tissue	1.2%
943	Smooth Muscle Tumor	1.2%
944	Adenomatosis, Pulmonary	1.2%
945	Adenomatous Polyps	1.2%
946	Carcinoma, Large Cell	1.2%
947	Carcinoma, Small Cell	1.2%
948	Desmoplastic Small Round Cell Tumor	1.2%
949	Chondroma	1.2%
950	Enchondroma	1.2%
951	Nasopharyngeal carcinoma	1.2%
952	Alexia, Pure	1.2%
953	Malignant Carcinoid Syndrome	1.2%
954	Primary amyloidosis	1.2%
955	Corneal Perforation	1.2%
956	Carcinoma, Endometrioid	1.1%
957	Dermatofibrosarcoma	1.1%
958	Dermatofibrosarcoma Protuberans	1.1%
959	Nasopharyngeal Neoplasms	1.1%
960	Colorectal Neoplasms	1.1%
961	Glioblastoma	1.1%
962	Neuroblastoma	1.1%
963	Glioblastoma Multiforme	1.1%
964	Tonsillar Neoplasms	1%
965	Paranasal Sinus Neoplasms	1%
966	Leukemia, Myelomonocytic, Chronic	1%
967	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	1%
968	Pheochromocytoma	1%
969	Alveolar rhabdomyosarcoma	1%
970	Ganglioneuroblastoma	0.9%
971	Waldenstrom Macroglobulinemia	0.9%
972	Multiple Myeloma	0.9%
973	Appendiceal Neoplasms	0.9%
974	Colonic Neoplasms	0.9%
975	Rectal Neoplasms	0.9%
976	Mucopolysaccharidosis II	0.9%
977	Carcinoid Heart Disease	0.9%
978	Mastocytosis	0.8%
979	Zollinger-Ellison syndrome	0.8%
980	Cell Transformation, Viral	0.8%
981	Gastrointestinal Stromal Tumors	0.8%
982	Hemangioma, Cavernous	0.8%
983	Leukemia, T-Cell	0.8%
984	Leukemia, B-Cell	0.8%
985	Adenoid Cystic Carcinoma	0.8%
986	fibroma	0.8%
987	Fibromatosis	0.8%
988	Lymphoma, Follicular	0.8%
989	Osteoblastoma	0.8%
990	Osteoma	0.8%
991	Rhabdomyoma	0.8%
992	T-Cell Lymphoma	0.8%
993	Chondromatosis	0.8%
994	Adenocarcinoma, Clear Cell	0.8%
995	Cholangiocarcinoma	0.8%
996	Cervical Intraepithelial Neoplasia	0.8%
997	Hemangioblastoma	0.8%
998	Lymphoma, Extranodal NK-T-Cell	0.8%
999	Mantle cell lymphoma	0.8%
1000	Maxillary Sinus Neoplasms	0.7%
1001	Anus Neoplasms	0.7%
1002	Sigmoid Neoplasms	0.7%
1003	Mastocytoma	0.6%
1004	Mastocytosis, Systemic	0.6%
1005	Leukemia, Myeloid, Chronic-Phase	0.6%
1006	Fibromatosis, Aggressive	0.6%
1007	Fibromatosis, Abdominal	0.6%
1008	Klatskin Tumor	0.6%
1009	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
1010	Leukemia, Large Granular Lymphocytic	0.5%
1011	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
1012	Lymphoma, T-Cell, Cutaneous	0.5%
1013	Lymphoma, AIDS-Related	0.5%
1014	Enteropathy-Associated T-Cell Lymphoma	0.5%
1015	Primary Effusion Lymphoma	0.5%
1016	Dupuytren Contracture	0.4%
1017	Urticaria Pigmentosa	0.4%
1018	Burkitt Lymphoma	0.4%
1019	Mycosis Fungoides	0.4%
1020	Lymphomatoid Papulosis	0.4%
1021	Plasmablastic lymphoma	0.4%
1022	Sezary Syndrome	0.3%
1023	Radicular Cyst	0.3%

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