MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Glioblastoma Multiforme

(UMLS:C1621958)

UMLS ID:: C1621958
MeSH ID:: D005909

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.465.625.600.380.080.335|C04.557.470.670.380.080.335|C04.557.580.625.600.380.080.335

Synonym(s)

Glioblastoma Multiforme

BRAIN TUMOR, GLIOBLASTOMA MULTIFORME

CANCER, GLIOBLASTOMA MULTIFORME

GBM - Glioblastoma multiforme

GLM - Glioblastoma multiforme

Glioblastoma

Glioblastoma multiforme

INTRACRANIAL NEOPLASM, GLIOBLASTOMA MULTIFORME

SPONGIOBLASTOMA MULTIFORME

10.

Spongioblastoma Multiforme

11.

Spongioblastoma multiforme

12.

glioblastoma multiforme

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Temozolomide	FAERS: 41 Canada Vigilance: 52	Canada Vigilance OFFSIDES US FAERS
2	Thalidomide	FAERS: 12	US FAERS
3	Lenalidomide	FAERS: 6	SIDER US FAERS
4	Isotretinoin	FAERS: 5	US FAERS
5	Clozapine	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
6	Dexamethasone	FAERS: 3	US FAERS
7	Carmustine	FAERS: 2	US FAERS
8	Dasatinib	FAERS: 2	US FAERS
9	Irinotecan	FAERS: 2	US FAERS
10	Lacosamide	FAERS: 2	OFFSIDES US FAERS
11	Levetiracetam	FAERS: 2	US FAERS
12	Valganciclovir	FAERS: 2	US FAERS
13	nitisinone	FAERS: 2	US FAERS
14	tofacitinib	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
15	4-Aminopyridine	FAERS: 1	US FAERS
16	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
17	Axitinib	FAERS: 1	US FAERS
18	Baclofen	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
19	Bosentan	FAERS: 1	US FAERS
20	Clopidogrel	FAERS: 1	US FAERS
21	Crizotinib	FAERS: 1	US FAERS
22	Diclofenac	FAERS: 1	US FAERS
23	Dimethyl Fumarate	FAERS: 1	US FAERS
24	Erlotinib Hydrochloride	FAERS: 1	US FAERS
25	Everolimus	FAERS: 1	US FAERS
26	Fentanyl	FAERS: 1	US FAERS
27	Fingolimod Hydrochloride	FAERS: 1	US FAERS
28	Glatiramer Acetate	FAERS: 1	OFFSIDES US FAERS
29	Imatinib Mesylate	FAERS: 1	US FAERS
30	Latanoprost	FAERS: 1	US FAERS
31	MDV 3100	FAERS: 1	US FAERS
32	Modafinil	FAERS: 1	US FAERS
33	Norgestrel	FAERS: 1	US FAERS
34	NuvaRing	FAERS: 1	US FAERS
35	Oxcarbazepine	FAERS: 1	US FAERS
36	PCI 32765	FAERS: 1	US FAERS
37	Pregabalin	FAERS: 1	US FAERS
38	Roflumilast	FAERS: 1	US FAERS
39	Sitagliptin Phosphate	FAERS: 1	US FAERS
40	Sunitinib	FAERS: 1	US FAERS
41	Tamoxifen	FAERS: 1	US FAERS
42	Teriparatide	FAERS: 1	US FAERS
43	Tolvaptan	FAERS: 1	US FAERS
44	Valganciclovir	FAERS: 1	US FAERS
45	Voriconazole	FAERS: 1	US FAERS
46	Zoledronic Acid	FAERS: 1	US FAERS
47	ambrisentan	FAERS: 1	US FAERS
48	efavirenz	FAERS: 1	US FAERS
49	lanreotide	FAERS: 1	US FAERS
50	teriflunomide	FAERS: 1	US FAERS
51	Aminocaproic Acid		OFFSIDES
52	Ascorbic Acid		OFFSIDES
53	Azathioprine		OFFSIDES
54	Betaxolol		OFFSIDES
55	Bromhexine		OFFSIDES
56	Cabergoline		OFFSIDES
57	Caffeine		OFFSIDES
58	Captopril		OFFSIDES
59	Celecoxib		OFFSIDES
60	Clomiphene		SIDER
61	Dapsone		OFFSIDES
62	Diphenhydramine		OFFSIDES
63	Doxorubicin		OFFSIDES
64	Etoposide		OFFSIDES
65	Glycerol		OFFSIDES
66	Glycyrrhizic Acid		OFFSIDES
67	Hydroxyurea		OFFSIDES
68	Mercaptopurine		OFFSIDES
69	Metoclopramide		OFFSIDES
70	Sodium picosulfate		OFFSIDES
71	Tretinoin		OFFSIDES
72	Tropisetron		OFFSIDES
73	Ubiquinone		OFFSIDES
74	Valacyclovir		OFFSIDES
75	azulene		OFFSIDES
76	cetraxate		OFFSIDES
77	dexamethasone acetate		OFFSIDES
78	geranylgeranylacetone		OFFSIDES
79	loxoprofen		OFFSIDES
80	ramelteon		OFFSIDES
81	ramosetron		OFFSIDES
82	rilmazafone		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Medulloblastoma	43.1%
2	Ependymoma	41.7%
3	oligodendroglioma	41.7%
4	Ganglioglioma	41.7%
5	gliosarcoma	41.7%
6	Anaplastic Oligodendroglioma	41.7%
7	Ganglioneuroma	38.3%
8	Craniopharyngioma	30.5%
9	Neuroectodermal Tumor, Melanotic	30.5%
10	Neuroendocrine Tumors	30.5%
11	leukemia	30.4%
12	melanoma	24.7%
13	Retinoblastoma	24.6%
14	Histiocytic Disorders, Malignant	24.4%
15	Adenoma	22.7%
16	Carcinoma	22.7%
17	Epithelioma	22.7%
18	Meningioma	22.7%
19	Adenoma, Acidophil	22.4%
20	Chordoma	22.3%
21	Teratoma	22.3%
22	Germinoma	22.3%
23	Teratocarcinoma	22.3%
24	Trophoblastic Neoplasms	22.1%
25	Hamartoma	20.5%
26	Neoplasms, Hormone-Dependent	20.5%
27	Neoplasms, Multiple Primary	20.5%
28	Paraneoplastic Syndromes	20.5%
29	Precancerous Conditions	20.5%
30	Neoplasms, Second Primary	20.5%
31	Lymphoma	20.4%
32	Neoplasms, Germ Cell and Embryonal	20.3%
33	Germ Cell Cancer	20.3%
34	Optic Nerve Glioma	20.3%
35	Neoplasms, Glandular and Epithelial	20%
36	Basal cell carcinoma	19.7%
37	Carcinoma, Papillary	19.7%
38	Squamous cell carcinoma	19.7%
39	Cystadenoma	19.7%
40	Mesothelioma	19.7%
41	Carcinoma, Basal Cell	19.7%
42	Carcinosarcoma	19.2%
43	Hemangiosarcoma	19.2%
44	lymphangiosarcoma	19.2%
45	Carcinoid Tumor	18.9%
46	Neurilemmoma	18.7%
47	Carcinoma, Ehrlich Tumor	18.1%
48	Carcinoma, Lewis Lung	18.1%
49	Composite Lymphoma	17.9%
50	Dermoid Cyst	17.8%
51	Leukemia, Experimental	17.3%
52	Paraganglioma	17%
53	Neuroectodermal Tumors	16.9%
54	Cyst	16.6%
55	Neoplastic Processes	16.6%
56	Neoplastic Syndromes, Hereditary	16.6%
57	Pregnancy Complications, Neoplastic	16.6%
58	Neoplasms, Experimental	16.4%
59	Leukemia, Plasma Cell	16%
60	Melanoma, Experimental	15.9%
61	Carcinoma 256, Walker	15.6%
62	Ameloblastoma	15.5%
63	Angiokeratoma	15.5%
64	Hemangioma	15.5%
65	hemangiopericytoma	15.5%
66	Lymphangioma	15.5%
67	Mesenchymoma	15.5%
68	Nevus	15.5%
69	Hepatoblastoma	15.5%
70	Mixed Tumor, Mullerian	15.5%
71	Angiofibroma	15.5%
72	Sarcoma	15.5%
73	Cystadenocarcinoma	15.5%
74	Mucoepidermoid Carcinoma	15.5%
75	Neuroblastoma	15.2%
76	Leukemia, Radiation-Induced	15.1%
77	Neoplasms, Neuroepithelial	14.4%
78	Gliomatosis cerebri	14.4%
79	Hutchinson's Melanotic Freckle	14.2%
80	Melanoma, Amelanotic	14.2%
81	Carcinoma, Lobular	14.2%
82	Acanthoma	14.1%
83	Choriocarcinoma	13.9%
84	Neoplasms, Radiation-Induced	13.7%
85	Chondrosarcoma	13.3%
86	leiomyosarcoma	13.3%
87	liposarcoma	13.3%
88	synovial sarcoma	13.3%
89	Angiomyolipoma	13.3%
90	Clear Cell Sarcoma of Soft Tissue	13.3%
91	Alveolar Soft Part Sarcoma	13.3%
92	Sarcoma, Myeloid	13.3%
93	Multiple Endocrine Neoplasia	13.2%
94	Plasmacytoma	12.5%
95	Malignant histiocytosis	12.5%
96	Histiocytic sarcoma	12.5%
97	Sarcoma, Experimental	12.4%
98	Thymoma	12.3%
99	Adenocarcinoma	12.3%
100	Carcinoma in Situ	12.3%
101	Carcinoma, Transitional Cell	12.3%
102	Papilloma	12.3%
103	Pseudomyxoma Peritonei	12.3%
104	Papillomatosis	12.3%
105	Adenomatosis, Pulmonary	12.3%
106	Adenomatous Polyps	12.3%
107	Carcinoma, Large Cell	12.3%
108	Carcinoma, Small Cell	12.3%
109	Adenofibroma	12.2%
110	Fibroadenoma	12.2%
111	Dysgerminoma	11.9%
112	Neuroma	11.9%
113	Seminoma	11.9%
114	Malignant Carcinoid Syndrome	11.7%
115	Endometrial Stromal Sarcoma	11.6%
116	Ganglioneuroblastoma	11.4%
117	Bowen's Disease	11.4%
118	Leukemia L1210	10.9%
119	Leukemia P388	10.9%
120	Paraneoplastic Encephalomyelitis	10.5%
121	Fibrosarcoma	10.4%
122	Osteosarcoma	10.4%
123	Tuberous Sclerosis	10.4%
124	Hodgkin Disease	10.4%
125	Lymphoma, Non-Hodgkin	10.4%
126	Pheochromocytoma	10.4%
127	Mammary Neoplasms, Experimental	10.3%
128	Abdominal Neoplasms	10.1%
129	Erythroplasia	10.1%
130	Follicular cyst	10.1%
131	Head and Neck Neoplasms	10.1%
132	Mucocele	10.1%
133	Pilonidal Cyst	10.1%
134	Soft Tissue Neoplasms	10.1%
135	Thoracic Neoplasms	10.1%
136	Thyroglossal Cyst	10.1%
137	Synovial Cyst	10.1%
138	Aberrant Crypt Foci	10.1%
139	Nephroblastoma	10%
140	Lymphangioleiomyomatosis	9.6%
141	Primary amyloidosis	9%
142	Malignant Fibrous Histiocytoma	9%
143	Basal Cell Nevus Syndrome	8.8%
144	Hepatocellular Adenoma	8.7%
145	Digestive System Neoplasms	8.5%
146	Endocrine Gland Neoplasms	8.5%
147	Eye Neoplasms	8.5%
148	Nervous System Neoplasms	8.5%
149	Lymphomatoid Granulomatosis	8.5%
150	Phyllodes Tumor	8.3%
151	Hemangioendothelioma	8.3%
152	Lipoma	8.3%
153	Myoma	8.3%
154	Myxoma	8.3%
155	Angiolipoma	8.3%
156	Myelolipoma	8.3%
157	Neoplasms, Bone Tissue	8.3%
158	Neoplasms, Fibrous Tissue	8.3%
159	Smooth Muscle Tumor	8.3%
160	Desmoplastic Small Round Cell Tumor	8.3%
161	Chondroma	8.3%
162	Enchondroma	8.3%
163	Bone neoplasms	8.3%
164	Leukoplakia	8.3%
165	Lymphocele	8.3%
166	Pancreatic Cyst	8.3%
167	Skin Neoplasms	8.3%
168	Hematologic Neoplasms	8.3%
169	Barrett Esophagus	8.1%
170	Breast Cyst	8.1%
171	Actinic keratosis	8.1%
172	Mediastinal Cyst	8.1%
173	Neoplasm Invasiveness	8.1%
174	Neoplasm Metastasis	8.1%
175	Neoplasm Recurrence, Local	8.1%
176	Parovarian Cyst	8.1%
177	Pericardial Cyst	8.1%
178	Splenic Neoplasms	8.1%
179	Thymic Cyst	8.1%
180	Carcinogenesis	8.1%
181	Myxoid cyst	8.1%
182	Metastasis	8.1%
183	Sarcoma 180	8%
184	neurofibroma	7.9%
185	Glioma	7.9%
186	Malignant Glioma	7.9%
187	Mesoblastic Nephroma	7.6%
188	Prolactinoma	7.6%
189	Growth Hormone-Secreting Pituitary Adenoma	7.6%
190	Rhabdomyosarcoma	7.6%
191	Giant Cell Tumor of Bone	7.6%
192	Acoustic Neuroma	7.3%
193	Neurofibrosarcoma	7.2%
194	Adenoid Cystic Carcinoma	7.1%
195	Adenocarcinoma, Clear Cell	7.1%
196	Cholangiocarcinoma	7.1%
197	Cervical Intraepithelial Neoplasia	7.1%
198	Waldenstrom Macroglobulinemia	7%
199	Multiple Myeloma	7%
200	Carcinoid Heart Disease	7%
201	Carcinoma, Pancreatic Ductal	7%
202	Corpus Luteum Cyst	6.8%
203	Ovarian Cysts	6.8%
204	Carcinoma, Ovarian Epithelial	6.7%
205	Leukemia, Myelomonocytic, Chronic	6.7%
206	Multiple Endocrine Neoplasia Type 1	6.7%
207	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	6.7%
208	Liver Neoplasms, Experimental	6.5%
209	Hydatidiform Mole	6.3%
210	Parathyroid Neoplasms	6.1%
211	Peritoneal Neoplasms	6.1%
212	Thyroid Neoplasm	6.1%
213	Thyroid carcinoma	6.1%
214	Dermatofibrosarcoma	6.1%
215	Dermatofibrosarcoma Protuberans	6.1%
216	Adenomatous Polyposis Coli	6.1%
217	Choledochal Cyst	5.9%
218	Peutz-Jeghers Syndrome	5.8%
219	Vipoma	5.7%
220	Mastocytosis	5.7%
221	Sturge-Weber Syndrome	5.7%
222	Gastrointestinal Stromal Tumors	5.6%
223	Hemangioma, Cavernous	5.6%
224	Leukemia, T-Cell	5.6%
225	Leukemia, B-Cell	5.6%
226	Lymphoma, Follicular	5.5%
227	T-Cell Lymphoma	5.5%
228	Mantle cell lymphoma	5.5%
229	Pancreatic Neoplasm	5.4%
230	Nasopharyngeal carcinoma	5.3%
231	Retroperitoneal Neoplasms	5.2%
232	granulosa cell tumor	5%
233	Astrocytoma	4.7%
234	fibroma	4.7%
235	Fibromatosis	4.7%
236	Osteoblastoma	4.7%
237	Osteoma	4.7%
238	Rhabdomyoma	4.7%
239	Chondromatosis	4.7%
240	Hemangioblastoma	4.7%
241	Anaplastic astrocytoma	4.7%
242	Lymphoma, Extranodal NK-T-Cell	4.7%
243	Alveolar rhabdomyosarcoma	4.7%
244	Tracheal Neoplasms	4.7%
245	Leukoplakia, Oral	4.6%
246	Paraneoplastic Cerebellar Degeneration	4.6%
247	insulinoma	4.6%
248	Klatskin Tumor	4.5%
249	Adrenocortical carcinoma	4.4%
250	Mouth Neoplasms	4.2%
251	Central Nervous System Neoplasms	4.2%
252	Vascular Neoplasms	4.2%
253	Thymus Neoplasms	4.2%
254	Genital Neoplasms, Female	4.2%
255	Pancreatic Pseudocyst	4.2%
256	Lymphatic Metastasis	4.2%
257	Neoplasms, Unknown Primary	4.2%
258	Leukemic Infiltration	4.2%
259	Breast Neoplasms, Male	4.2%
260	Neoplasm Micrometastasis	4.2%
261	Triple Negative Breast Neoplasms	4.2%
262	Esophageal Neoplasms	4.1%
263	Limbic Encephalitis	4%
264	Renal Cell Carcinoma	3.9%
265	Papillary Renal Cell Carcinoma	3.9%
266	Denys-Drash Syndrome	3.9%
267	Mastocytoma	3.8%
268	Mastocytosis, Systemic	3.8%
269	Leukemia, Myeloid, Chronic-Phase	3.8%
270	Xeroderma Pigmentosum	3.7%
271	Lambert-Eaton Myasthenic Syndrome	3.6%
272	Testicular Neoplasms	3.6%
273	Carcinoma, Endometrioid	3.6%
274	Adrenal Gland Neoplasms	3.6%
275	Gastrointestinal Neoplasms	3.6%
276	Genital Neoplasms, Male	3.6%
277	Liver neoplasms	3.6%
278	Uveal Neoplasms	3.6%
279	Urologic Neoplasms	3.5%
280	Sebaceous Gland Neoplasms	3.5%
281	Spinal Neoplasms	3.5%
282	Bone Marrow Neoplasms	3.5%
283	Polycystic Ovary Syndrome	3.5%
284	Gastrinoma	3.4%
285	Glucagonoma	3.4%
286	Opsoclonus-Myoclonus Syndrome	3.3%
287	Thyroid Nodule	3.2%
288	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.2%
289	Leukemia, Large Granular Lymphocytic	3.2%
290	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.2%
291	Lymphoma, T-Cell, Cutaneous	3.1%
292	Lymphoma, AIDS-Related	3.1%
293	Enteropathy-Associated T-Cell Lymphoma	3.1%
294	Primary Effusion Lymphoma	3.1%
295	Glioblastoma	3.1%
296	Glioblastoma Multiforme	3.1%
297	Fibromatosis, Aggressive	2.9%
298	Fibromatosis, Abdominal	2.9%
299	Myelitis, Transverse	2.9%
300	Leydig Cell Tumor	2.9%
301	ovarian neoplasm	2.6%
302	Burkitt Lymphoma	2.4%
303	Nose Neoplasms	2.3%
304	Meningeal Neoplasms	2.2%
305	Pituitary Adenoma	2.2%
306	Pituitary Neoplasms	2.2%
307	Zollinger-Ellison syndrome	2.1%
308	Dupuytren Contracture	2%
309	Urticaria Pigmentosa	2%
310	Palatal Neoplasms	2%
311	Mycosis Fungoides	2%
312	Lymphomatoid Papulosis	2%
313	Plasmablastic lymphoma	2%
314	Ear Neoplasms	1.9%
315	Eyelid Neoplasms	1.9%
316	Lung Neoplasms	1.9%
317	Pleural Neoplasms	1.9%
318	Cell Transformation, Viral	1.9%
319	Brain Neoplasms	1.9%
320	Salivary Gland Neoplasms	1.9%
321	Spinal Cord Neoplasms	1.9%
322	Tongue Neoplasms	1.9%
323	Uterine Neoplasms	1.9%
324	Vaginal Neoplasms	1.9%
325	Vulvar Neoplasms	1.9%
326	Uterine Cancer	1.9%
327	Fallopian Tube Neoplasms	1.9%
328	Pharyngeal Neoplasms	1.7%
329	Central Nervous System Cysts	1.6%
330	Bile Duct Neoplasms	1.6%
331	gallbladder neoplasm	1.6%
332	Intestinal Neoplasms	1.6%
333	Penile Neoplasms	1.6%
334	Prostatic Neoplasms	1.6%
335	Stomach Neoplasms	1.6%
336	Polycythemia Vera	1.6%
337	Sezary Syndrome	1.5%
338	Laryngeal neoplasm	1.5%
339	Bladder Neoplasm	1.4%
340	Kidney Neoplasm	1.4%
341	Ureteral Neoplasms	1.4%
342	Urethral Neoplasms	1.4%
343	Meningeal Carcinomatosis	1.3%
344	Bronchial Neoplasms	1.1%
345	Multiple Pulmonary Nodules	1.1%
346	Supratentorial Neoplasms	1.1%
347	Endometrial Neoplasms	1.1%
348	Hypopharyngeal Neoplasms	0.9%
349	Pleural Effusion, Malignant	0.9%
350	Hypopharyngeal Cancer	0.9%
351	Parotid Neoplasms	0.9%
352	Prostatic Neoplasms, Castration-Resistant	0.9%
353	Nelson Syndrome	0.9%
354	Cecal Neoplasms	0.8%
355	Duodenal Neoplasms	0.8%
356	Nasopharyngeal Neoplasms	0.7%
357	Colorectal Neoplasms	0.7%
358	Brain Stem Neoplasms	0.7%
359	Paranasal Sinus Neoplasms	0.7%
360	Tonsillar Neoplasms	0.6%
361	Cerebellar Neoplasms	0.6%
362	Radicular Cyst	0.5%
363	Appendiceal Neoplasms	0.5%
364	Colonic Neoplasms	0.5%
365	Rectal Neoplasms	0.5%
366	Choroid Plexus Papilloma	0.5%
367	Maxillary Sinus Neoplasms	0.4%
368	Anus Neoplasms	0.3%
369	Sigmoid Neoplasms	0.3%

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