MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sleep Disorders, Circadian Rhythm

(UMLS:C0877792)

Definition:: Dyssomnias associated with disruption of the normal 24 hour sleep wake cycle secondary to travel (e.g., JET LAG SYNDROME), shift work, or other causes.
UMLS ID:: C0877792
MeSH ID:: D020178

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.281.800|C10.886.425.200

Classification 2:

Name:

Occupational Diseases
MeSH Tree Number(s):: C24.900

Classification 3:

Name:

Mental Disorders
MeSH Tree Number(s):: F03.870.400.200

Synonym(s)

Sleep Disorders, Circadian Rhythm

Circadian Rhythm Sleep Disorder

Circadian rhythm sleep disorder

Circadian rhythm sleep disorder, NOS

Circadian rhythm sleep-wake disorder

Disorder of sleep-wake cycle

Disorder of sleep-wake schedule

Disorders of the sleep-wake schedule

Disturbed nyctohemeral rhythm

10.

Sleep rhythm problem

11.

Sleep-wake schedule disorder, NOS

12.

circadian rhythm sleep disorder

13.

circadian rhythm sleep disorders

14.

circadian rhythm; sleep disorder

15.

sleep disorder circadian rhythm

16.

sleep disorder; circadian rhythm

17.

sleep disorder; sleep-wake pattern or schedule

18.

sleep wake schedule disorder

19.

sleep-wake pattern or schedule; sleep disorder

20.

sleep-wake schedule disorder

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Haloperidol	9463841 12405556	CTD
2	Melatonin	View details 9095378 11684046 12405556 18078449 19452292 25395965	CTD
3	Phenelzine	3273886	CTD
4	Tranylcypromine	3273886	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Restless Legs Syndrome	38.4%
2	Sleep Disorders, Intrinsic	36%
3	Disorders of Excessive Somnolence	27%
4	Sleep Initiation and Maintenance Disorders	27%
5	Transient Insomnia	27%
6	Chronic Insomnia	27%
7	Hypersomnia	27%
8	Sleep Deprivation	26.6%
9	Parasomnia	26.2%
10	Nocturnal Myoclonus Syndrome	25.4%
11	Narcolepsy	22.6%
12	Kleine-Levin Syndrome	22.6%
13	Cataplexy	20.4%
14	Multiple System Atrophy	18.2%
15	Sleep Talking	17.4%
16	Motor Neuron Disease	16.7%
17	Stiff-Person Syndrome	16.7%
18	Cranial nerve diseases	16.2%
19	Demyelinating Diseases	16.2%
20	Demyelination	16.2%
21	Neuromuscular Diseases	16.2%
22	Polyradiculoneuropathy	15.7%
23	Polyradiculoneuritis	15.7%
24	Ophthalmoplegic Migraine	15.6%
25	Lewy Body Disease	15.6%
26	Meningoencephalitis	15.4%
27	Amyotrophic Lateral Sclerosis	15.2%
28	Sleep Apnea Syndromes	15%
29	Spinal Muscular Atrophy	14.9%
30	Sleep Bruxism	14.9%
31	Progressive Muscular Atrophy	14.9%
32	Subacute Combined Degeneration	14.6%
33	Ocular Motility Disorders	14.6%
34	Cyclophoria	14.6%
35	Parkinson Disease	14.3%
36	Encephalomyelitis	14.1%
37	Prion Diseases	14.1%
38	Autonomic Dysreflexia	14.1%
39	Complex Regional Pain Syndromes	14.1%
40	Striatonigral Degeneration	14%
41	Guillain-Barre Syndrome	14%
42	Leukoencephalitis, Acute Hemorrhagic	13.8%
43	Trauma, Nervous System	13.8%
44	Miller Fisher Syndrome	13.6%
45	Progressive supranuclear palsy	13.5%
46	Nervous System Neoplasms	13.4%
47	Neurologic Manifestations	13.4%
48	Neurotoxicity Syndromes	13.4%
49	Hand-Arm Vibration Syndrome	13.4%
50	Jet Lag Syndrome	13.4%
51	Night Terrors	13.2%
52	Somnambulism	13.2%
53	Sleep Paralysis	13.2%
54	REM Sleep Behavior Disorder	13.2%
55	Smith-Magenis syndrome	13%
56	Dandy-Walker Syndrome	12.9%
57	Myelitis, Transverse	12.9%
58	Pneumocephalus	12.9%
59	Poliomyelitis	12.9%
60	Marchiafava-Bignami Disease	12.9%
61	Causalgia	12.7%
62	Sleep Apnea, Obstructive	12.6%
63	Sleep Apnea, Central	12.6%
64	Huntington Disease	12.6%
65	Shy-Drager Syndrome	12.4%
66	Spinal Cord Injuries	12.4%
67	Neuromyelitis Optica	12.3%
68	Peripheral Nerve Injuries	12.1%
69	Myasthenia Gravis	12%
70	Asterixis	12%
71	Ballismus	12%
72	Epidural Abscess	12%
73	Olfactory Nerve Injuries	12%
74	Opsoclonus-Myoclonus Syndrome	11.8%
75	MPTP Poisoning	11.8%
76	Agricultural Workers' Diseases	11.8%
77	Persian Gulf Syndrome	11.8%
78	Lambert-Eaton Myasthenic Syndrome	11.7%
79	Myelitis	11.6%
80	Progressive bulbar palsy	11.6%
81	Bulbar palsy	11.6%
82	Encephalomyelitis, Acute Disseminated	11.5%
83	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	11.5%
84	Leukoencephalopathy, Progressive Multifocal	11.1%
85	Dystonia Musculorum Deformans	11.1%
86	Dyskinesia, Drug-Induced	11%
87	Neuroleptic Malignant Syndrome	10.9%
88	Myelinolysis, Central Pontine	10.9%
89	Presenile dementia	10.8%
90	Senile dementia	10.8%
91	Chronic Fatigue Syndrome	10.8%
92	Facial Nerve Injuries	10.6%
93	Dementia, Vascular	10.5%
94	Lupus Vasculitis, Central Nervous System	10.4%
95	Reflex Sympathetic Dystrophy	10.4%
96	Subdural Effusion	10.4%
97	Parkinsonian Disorders	10.4%
98	Botulism	10.4%
99	Central Nervous System Cysts	10.4%
100	Epilepsy, Post-Traumatic	10.2%
101	Brain Diseases	10%
102	Dysautonomia	10%
103	Meningitis	10%
104	Movement Disorders	10%
105	Pachymeningitis	10%
106	Spinal Cord Diseases	10%
107	Vagus Nerve Disorder	10%
108	Glossopharyngeal Neuralgia	10%
109	Abducens Nerve Diseases	10%
110	Heavy Metal Poisoning, Nervous System	10%
111	Neuromuscular Junction Diseases	10%
112	Tauopathies	10%
113	Trochlear Nerve Diseases	10%
114	Peripheral Nervous System Diseases	10%
115	Brain Injuries	9.9%
116	Brain Neoplasms	9.9%
117	Multiple Sclerosis	9.9%
118	Spinal Cord Neoplasms	9.9%
119	Limbic Encephalitis	9.8%
120	Creutzfeldt-Jakob disease	9.8%
121	Neurotic Disorders	9.8%
122	Lafora Disease	9.5%
123	Unverricht-Lundborg Syndrome	9.5%
124	Horner Syndrome	9.5%
125	Myasthenia Gravis, Autoimmune, Experimental	9.5%
126	Dementia	9.4%
127	Charcot-Marie-Tooth Disease	9.4%
128	Canavan Disease	9.3%
129	Alexander Disease	9.3%
130	Cerebellar Neoplasms	9.3%
131	Akathisia, Drug-Induced	9.2%
132	Brain Hemorrhage, Traumatic	9.2%
133	Meige Syndrome	9.2%
134	Brachial Plexus Neuritis	9.2%
135	Neuralgic Amyotrophy	9.2%
136	Cerebral Ventriculitis	9.2%
137	Scrapie	9%
138	Central Cord Syndrome	9%
139	Meningitis, Bacterial	8.9%
140	Meningitis, Fungal	8.9%
141	Chorea	8.8%
142	Acrodynia	8.8%
143	Brain Abscess	8.7%
144	Ophthalmoplegia	8.7%
145	External Ophthalmoplegia	8.7%
146	Friedreich Ataxia	8.6%
147	Tarsal Tunnel Syndrome	8.6%
148	Cauda Equina Syndrome	8.6%
149	Posterior Leukoencephalopathy Syndrome	8.6%
150	Posterior reversible encephalopathy syndrome	8.6%
151	Central Nervous System Infection	8.5%
152	Myopathy	8.5%
153	Optic Neuropathy	8.5%
154	Tuberous Sclerosis	8.5%
155	Ataxia Telangiectasia	8.5%
156	Vasculitis, Central Nervous System	8.4%
157	Facial Nerve Diseases	8.3%
158	Craniocerebral Trauma	8.3%
159	Vestibulocochlear Nerve Diseases	8.2%
160	Decerebrate State	8.2%
161	Hemiparesis	8.2%
162	Hydranencephaly	8.2%
163	Meningism	8.2%
164	Neural Tube Defects	8.2%
165	Paresis	8.2%
166	Seizures	8.2%
167	Sensation Disorders	8.2%
168	Tethered Cord Syndrome	8.2%
169	Central Nervous System Neoplasms	8.2%
170	Complex partial seizures	8.2%
171	Iniencephaly	8.2%
172	Craniorachischisis	8.2%
173	Exencephaly	8.2%
174	Monoparesis	8.2%
175	Septo-Optic Dysplasia	8.2%
176	Cortical Dysplasia	8.2%
177	Neurogenic Inflammation	8.2%
178	Gait Disorders, Neurologic	8.2%
179	Neuromuscular Manifestations	8.2%
180	Malformations of Cortical Development	8.2%
181	Sweating, Gustatory	8.2%
182	Auriculotemporal Syndrome	8.2%
183	Tuberculosis, Meningeal	8.2%
184	Pneumoconiosis	8.2%
185	Brain Death	8.1%
186	Coma, Post-Head Injury	8.1%
187	Dermatitis, Occupational	8.1%
188	Carotid Artery Injuries	8.1%
189	Myoclonic Epilepsy	8%
190	Epilepsy, Temporal Lobe	8%
191	Epilepsy, Rolandic	8%
192	Benign Rolandic Epilepsy	8%
193	Amnesia, Transient Global	7.9%
194	Basal Ganglia Cerebrovascular Disease	7.8%
195	Hepatolenticular Degeneration	7.8%
196	Brain Injuries, Diffuse	7.8%
197	Traumatic Brain Injury	7.8%
198	Cerebellar Ataxia	7.8%
199	Supratentorial Neoplasms	7.8%
200	Torticollis	7.8%
201	Multiple Sclerosis, Chronic Progressive	7.8%
202	Multiple Sclerosis, Relapsing-Remitting	7.8%
203	Amblyopia	7.7%
204	Myotonia Congenita	7.7%
205	Vocal Cord Paralysis	7.7%
206	Paraneoplastic Cerebellar Degeneration	7.7%
207	Myotonic Dystrophy	7.7%
208	Cerebrospinal Fluid Otorrhea	7.7%
209	Cerebrospinal Fluid Rhinorrhea	7.7%
210	Neuritis, Autoimmune, Experimental	7.7%
211	Gait Ataxia	7.6%
212	Frontotemporal dementia	7.6%
213	Pituitary Adenoma	7.6%
214	Pituitary Neoplasms	7.6%
215	Alice in Wonderland Syndrome	7.5%
216	Juvenile Myoclonic Epilepsy	7.4%
217	Myoclonic Epilepsies, Progressive	7.4%
218	Brain Concussion	7.4%
219	Anxiety Disorders	7.4%
220	Avoidant Personality Disorder	7.4%
221	Dissociative disorder	7.4%
222	Frigidity	7.4%
223	Hypoactive Sexual Desire Disorder	7.4%
224	Disruptive, Impulse Control, and Conduct Disorders	7.4%
225	Intermittent Explosive Disorder	7.4%
226	Kleptomania	7.4%
227	Narcissistic Personality Disorder	7.4%
228	Personality Disorders	7.4%
229	Sexual Aversion Disorder	7.4%
230	Somatoform Disorder	7.4%
231	Dissociation	7.4%
232	Motor Disorders	7.4%
233	Chronobiology Disorders	7.4%
234	Mood Disorders	7.4%
235	Schizophrenia Spectrum and Other Psychotic Disorders	7.4%
236	Neurodevelopmental Disorders	7.4%
237	Neurocognitive Disorders	7.4%
238	Feeding and Eating Disorders	7.4%
239	Carpal Tunnel Syndrome	7.3%
240	Vascular Headaches	7.3%
241	neurofibroma	7.3%
242	Hypoxia-Ischemia, Brain	7.3%
243	Optic Nerve Glioma	7.3%
244	Sciatica	7.3%
245	Tardive Dyskinesia	7.3%
246	Persistent Vegetative State	7.3%
247	Pupil Disorders	7.2%
248	Neurobehavioral Manifestations	7.2%
249	Separation Anxiety Disorder	7.1%
250	Paraneoplastic Encephalomyelitis	7.1%
251	Refsum Disease	7.1%
252	Akinetic Mutism	7%
253	Anoxic Encephalopathy	7%
254	Arachnoiditis	7%
255	Basal Ganglia Diseases	7%
256	Brain Damage, Chronic	7%
257	Cerebellar Diseases	7%
258	Encephalitis	7%
259	Encephalomalacia	7%
260	Epilepsy	7%
261	Hydrocephalus	7%
262	Congenital Hydrocephalus	7%
263	Hypothalamic Diseases	7%
264	Aseptic Meningitis	7%
265	Neuritis	7%
266	Polyneuritis	7%
267	Radiculitis	7%
268	Syringomyelia	7%
269	Thalamic Diseases	7%
270	Intracranial Hypertension	7%
271	Polyneuropathy	7%
272	Mononeuritis	7%
273	Aura	7%
274	Leukoencephalopathy	7%
275	Essential Tremor	7%
276	Neuroaxonal Dystrophies	7%
277	Familial Tremor	7%
278	Headache Disorders	7%
279	Mononeuropathies	7%
280	Intracranial Hypotension	7%
281	Brachial Plexus Neuropathies	7%
282	Radiculopathy	7%
283	Mononeuropathy Multiplex	7%
284	Nerve Root Compression	7%
285	Brain Edema	7%
286	Brain Hypoxia	7%
287	Aqueductal Stenosis	7%
288	Pneumorrhachis	7%
289	Writer's Cramp	7%
290	Asthma, Occupational	7%
291	Toxoplasmosis, Cerebral	7%
292	Uveomeningoencephalitic Syndrome	7%
293	Consciousness Disorders	7%
294	Mental Retardation	7%
295	Depressed Level of Consciousness	7%
296	Mental deficiency	7%
297	Intellectual Disability	7%
298	Sturge-Weber Syndrome	7%
299	Vertigo	7%
300	Alcohol-Induced Disorders, Nervous System	7%
301	Kluver-Bucy Syndrome	6.9%
302	Leukomalacia, Periventricular	6.8%
303	Basal Ganglia Hemorrhage	6.8%
304	Cubital Tunnel Syndrome	6.8%
305	Akathisia	6.8%
306	Diffuse Axonal Injury	6.8%
307	Restlessness	6.8%
308	Psychomotor Agitation	6.8%
309	Brain Stem Neoplasms	6.8%
310	Alcohol Withdrawal Seizures	6.8%
311	Auditory Perceptual Disorders	6.7%
312	Alexia	6.7%
313	Dyslexia	6.7%
314	Alstrom Syndrome	6.4%
315	Vertebral Artery Dissection	6.4%
316	Meningitis, Cryptococcal	6.4%
317	Putaminal Hemorrhage	6.4%
318	Gait Apraxia	6.4%
319	Meningitis, Listeria	6.3%
320	Subarachnoid Hemorrhage, Traumatic	6.3%
321	Carotid Artery, Internal, Dissection	6.3%
322	Meningitis, Haemophilus	6.3%
323	Meningitis, Pneumococcal	6.3%
324	Subacute Sclerosing Panencephalitis	6.3%
325	Sleep Wake Disorders	6.3%
326	Infarction, Middle Cerebral Artery	6.3%
327	Infarction, Anterior Cerebral Artery	6.3%
328	Infarction, Posterior Cerebral Artery	6.3%
329	Choroid Plexus Papilloma	6.3%
330	Drug abuse	6.2%
331	Substance Dependence	6.2%
332	Substance-Related Disorders	6.2%
333	Drug Dependence	6.2%
334	Voice Disorders	6.2%
335	Voice Disturbance	6.2%
336	Adrenoleukodystrophy	6.2%
337	Mutism	6.1%
338	Selective Mutism	6.1%
339	Alcohol Withdrawal Delirium	6.1%
340	Dural Arteriovenous Fistula	6.1%
341	Mitochondrial Encephalomyopathies	6%
342	Amnesia	6%
343	Delirium	6%
344	Dissociative Amnesia	6%
345	Global Amnesia	6%
346	Pituitary Apoplexy	6%
347	Asbestosis	5.9%
348	Berylliosis	5.9%
349	Silicosis	5.9%
350	Brain Contusion	5.9%
351	Brain Infarction	5.9%
352	Brain Diseases, Metabolic	5.9%
353	Cerebrovascular Disorders	5.9%
354	Myositis	5.9%
355	Optic Atrophy	5.9%
356	Optic Neuritis	5.9%
357	Papilledema	5.9%
358	Strabismus	5.9%
359	Tolosa-Hunt Syndrome	5.9%
360	Cerebrovascular Insufficiency	5.9%
361	Isaacs syndrome	5.9%
362	Arsenic Poisoning	5.9%
363	Myotonic Disorders	5.9%
364	Central Nervous System Fungal Infections	5.9%
365	Conus Medullaris Syndrome	5.9%
366	Myasthenic Syndromes, Congenital	5.9%
367	Spinal Cord Vascular Diseases	5.9%
368	Diabetic Neuropathies	5.8%
369	Facial Injuries	5.8%
370	Facial Neuralgia	5.8%
371	Diabetic Amyotrophy	5.8%
372	Diabetic Autonomic Neuropathy	5.8%
373	Manganese Poisoning	5.8%
374	Orthostatic intolerance	5.8%
375	Anosmia	5.8%
376	Ataxia	5.8%
377	Athetosis	5.8%
378	Catalepsy	5.8%
379	Dystonia	5.8%
380	Hemiplegia	5.8%
381	Locked-In Syndrome	5.8%
382	Meningeal Neoplasms	5.8%
383	Meningomyelocele	5.8%
384	Muscle Hypertonia	5.8%
385	Muscle hypotonia	5.8%
386	Myoclonus	5.8%
387	Myotonia	5.8%
388	Neuralgia	5.8%
389	Paraplegia	5.8%
390	Pseudobulbar Palsy	5.8%
391	Quadriplegia	5.8%
392	Spasm	5.8%
393	Spastic Paraplegia	5.8%
394	Status Epilepticus	5.8%
395	Taste Disorders	5.8%
396	Tremor	5.8%
397	Spina Bifida	5.8%
398	Monoplegia	5.8%
399	Hypokinesia	5.8%
400	Paraparesis	5.8%
401	Bradykinesia	5.8%
402	Waxy flexibility	5.8%
403	Action Tremor	5.8%
404	Resting Tremor	5.8%
405	Dysosmia	5.8%
406	Quadriparesis	5.8%
407	Mercury Poisoning, Nervous System	5.8%
408	Olfaction Disorders	5.8%
409	Myokymia	5.8%
410	Lead Poisoning, Nervous System	5.8%
411	Vestibular Neuronitis	5.8%
412	Somatosensory Disorders	5.8%
413	Neuropathic pain	5.8%
414	Hyperkinesia	5.8%
415	Intention tremor	5.8%
416	Cerebral Palsy	5.6%
417	Epilepsies, Partial	5.6%
418	Epilepsy, Generalized	5.6%
419	Pseudotumor Cerebri	5.6%
420	Sciatic Neuropathy	5.6%
421	Hypertensive Encephalopathy	5.6%
422	Ulnar Neuropathies	5.6%
423	Lesion of Sciatic Nerve	5.6%
424	Simple Partial Seizures	5.6%
425	Epilepsy, Reflex	5.6%
426	Ulnar Neuritis	5.6%
427	Radial nerve compression	5.6%
428	Radial Tunnel Syndrome	5.6%
429	Peroneal Neuropathies	5.6%
430	Radial Neuropathy	5.6%
431	Median Neuropathy	5.6%
432	Sciatic Nerve Palsy	5.6%
433	Femoral Neuropathy	5.6%
434	Tibial Neuropathy	5.6%
435	Ulnar Nerve Palsy	5.6%
436	Postural Orthostatic Tachycardia Syndrome	5.6%
437	Radial nerve palsy	5.6%
438	Headache Disorders, Primary	5.6%
439	Headache Disorders, Secondary	5.6%
440	Medication overuse headache	5.6%
441	Classical Lissencephalies and Subcortical Band Heterotopias	5.6%
442	Amyloid Neuropathies, Familial	5.5%
443	Cerebral Infarction	5.5%
444	Brain Stem Infarctions	5.5%
445	Dyscalculia	5.4%
446	Sleep Disorders, Circadian Rhythm	5.4%
447	West Nile Fever	5.4%
448	MELAS Syndrome	5.3%
449	Reflex, Abnormal	5.3%
450	Hyporeflexia	5.3%
451	Hyperreflexia	5.3%
452	Lateral Medullary Syndrome	5.2%
453	Giant Cell Arteritis	5.2%
454	Temporal Arteritis	5.2%
455	Farmer's Lung	5.2%
456	Acoustic Neuroma	5.1%
457	Pick Disease of the Brain	5.1%
458	Vision Disorders	5.1%
459	Metamorphopsia	5.1%
460	Visual Impairment	5.1%
461	Fibromyalgia	5.1%
462	Optic Neuropathy, Ischemic	5.1%
463	Anterior Ischemic Optic Neuropathy	5.1%
464	Central Nervous System Bacterial Infections	5.1%
465	Medial Tibial Stress Syndrome	5.1%
466	Moyamoya Disease	5%
467	Facial Hemiatrophy	5%
468	Melkersson-Rosenthal Syndrome	5%
469	Mitochondrial Myopathies	5%
470	Neurofibrosarcoma	5%
471	Alexia, Pure	5%
472	Anisocoria	5%
473	Confusion	5%
474	Facial paralysis	5%
475	Lethargy	5%
476	Memory Disorders	5%
477	Muscle Cramp	5%
478	Perceptual Disorders	5%
479	Psychomotor Disorders	5%
480	Tonic Pupil	5%
481	Eosinophilia-Myalgia Syndrome	5%
482	Anhedonia	5%
483	Disorientation	5%
484	Facial Paresis	5%
485	Memory Loss	5%
486	Hemisensory Neglect	5%
487	Dysacusis	5%
488	Kearns-Sayre syndrome	5%
489	Anencephaly	4.9%
490	Meningocele	4.9%
491	Muscular Atrophy	4.9%
492	Respiratory Paralysis	4.9%
493	Encephalocele	4.9%
494	Tetany	4.9%
495	Polyradiculopathy	4.9%
496	Post-Traumatic Headache	4.9%
497	Tension Headache	4.9%
498	Epilepsy, Complex Partial	4.9%
499	Migraine Disorders	4.9%
500	Abdominal Migraine	4.9%
501	Status Migrainosus	4.9%
502	Cervicogenic Headache	4.9%
503	Hematoma, Subdural	4.8%
504	Hematoma, Epidural, Cranial	4.8%
505	Pituitary Diseases	4.8%
506	Dyssomnias	4.8%
507	Thoracic Outlet Syndrome	4.7%
508	Retrograde amnesia	4.7%
509	Amnesia, Anterograde	4.7%
510	Carotid Artery Diseases	4.6%
511	Brain Ischemia	4.6%
512	Esotropia	4.6%
513	Exotropia	4.6%
514	Hypotension, Orthostatic	4.6%
515	Cerebrovascular accident	4.6%
516	Polymyositis	4.6%
517	Vasospasm, Intracranial	4.6%
518	Spinal Cord Ischemia	4.6%
519	Intracranial Arterial Diseases	4.6%
520	Post-Exercise Hypotension	4.6%
521	Trigeminal Nerve Disorder	4.6%
522	Dermal Sinus	4.6%
523	Dysgeusia	4.6%
524	Formication	4.6%
525	Hyperalgesia	4.6%
526	Hyperesthesia	4.6%
527	Hypesthesia	4.6%
528	Language Disorders	4.6%
529	Numbness	4.6%
530	Paresthesia	4.6%
531	Paraparesis, Spastic	4.6%
532	Spina Bifida Cystica	4.6%
533	Trismus	4.6%
534	Spina Bifida Occulta	4.6%
535	Epilepsia Partialis Continua	4.6%
536	Hypogeusia	4.6%
537	Meningeal Carcinomatosis	4.6%
538	Brown-Sequard Syndrome	4.6%
539	Lissencephaly	4.6%
540	Polymicrogyria	4.6%
541	Pachygyria	4.6%
542	Schizencephaly	4.6%
543	Lockjaw	4.6%
544	Allodynia	4.6%
545	Lead Poisoning, Nervous System, Childhood	4.6%
546	Lead Poisoning, Nervous System, Adult	4.6%
547	Periventricular Nodular Heterotopia	4.6%
548	Ageusia	4.6%
549	Optic Atrophy, Hereditary, Leber	4.6%
550	Tuberculosis, Central Nervous System	4.6%
551	Wernicke Encephalopathy	4.5%
552	Cluster Headache	4.5%
553	Migraine with Aura	4.5%
554	Familial Hemiplegic Migraine	4.5%
555	Chronic Paroxysmal Hemicrania	4.5%
556	SUNCT Syndrome	4.5%
557	Paroxysmal Hemicrania	4.5%
558	AIDS Dementia Complex	4.5%
559	Psychoses, Substance-Induced	4.4%
560	Hematoma, Subdural, Intracranial	4.4%
561	Hematoma, Subdural, Chronic	4.4%
562	Hematoma, Subdural, Acute	4.4%
563	Duane Retraction Syndrome	4.4%
564	Muscle Weakness	4.4%
565	Mobius Syndrome	4.3%
566	Bell Palsy	4.3%
567	Catatonia	4.3%
568	Herpes Zoster Oticus	4.3%
569	Familial Periodic Paralysis	4.3%
570	Aphonia	4.3%
571	Dysphonia	4.3%
572	Adjustment Disorders	4.3%
573	Affective Disorders, Psychotic	4.3%
574	Agoraphobia	4.3%
575	Anorexia Nervosa	4.3%
576	Antisocial Personality Disorder	4.3%
577	Bipolar Disorder	4.3%
578	Body Dysmorphic Disorders	4.3%
579	Borderline Personality Disorder	4.3%
580	Capgras Syndrome	4.3%
581	Child Behavior Disorders	4.3%
582	Developmental Disabilities	4.3%
583	Child Development Disorders, Pervasive	4.3%
584	Claustrophobia	4.3%
585	Cognition Disorders	4.3%
586	Conversion disorder	4.3%
587	Cyclothymic Disorder	4.3%
588	Dependent Personality Disorder	4.3%
589	Depressive disorder	4.3%
590	Developmental Coordination Disorder	4.3%
591	Exhibitionism	4.3%
592	Factitious Disorders	4.3%
593	Firesetting Behavior	4.3%
594	Head Banging	4.3%
595	Histrionic Personality Disorder	4.3%
596	Hypochondriasis	4.3%
597	Masochism	4.3%
598	Melancholia	4.3%
599	Motor Skills Disorders	4.3%
600	Dissociative Identity Disorder	4.3%
601	Neurasthenia	4.3%
602	Obsessive-Compulsive Disorder	4.3%
603	Oppositional Defiant Disorder	4.3%
604	Panic Disorder	4.3%
605	Paranoid Personality Disorder	4.3%
606	Pedophilia	4.3%
607	Pseudodementia	4.3%
608	Psychotic Disorders	4.3%
609	Sadism	4.3%
610	Schizoaffective Disorder	4.3%
611	Schizoid Personality Disorder	4.3%
612	Schizophrenia	4.3%
613	Schizophrenia, Childhood	4.3%
614	Schizotypal Personality Disorder	4.3%
615	Stereotypic Movement Disorder	4.3%
616	Transvestism	4.3%
617	Trichotillomania	4.3%
618	Voyeurism	4.3%
619	Attention Deficit and Disruptive Behavior Disorders	4.3%
620	Hyperkinetic Heart Syndrome	4.3%
621	Reactive Attachment Disorder	4.3%
622	Sexual and Gender Disorders	4.3%
623	Gender Dysphoria	4.3%
624	Paranoia	4.3%
625	Compulsive Personality Disorder	4.3%
626	Bulimia Nervosa	4.3%
627	Empty Sella Syndrome	4.1%
628	Hyperpituitarism	4.1%
629	Hypopituitarism	4.1%
630	Hypophysitis	4.1%
631	Eye Injuries	4%
632	Cerebral Arterial Diseases	4%
633	Vertebrobasilar Insufficiency	4%
634	Anterior Spinal Artery Syndrome	4%
635	Basilar Artery Stenosis	4%
636	Vertebral Artery Stenosis	4%
637	Intracranial Hemorrhage, Hypertensive	4%
638	Transient Cerebral Ischemia	4%
639	Trigeminal Neuralgia	4%
640	Agraphia	4%
641	Anomia	4%
642	Cluttering	4%
643	Language Development Disorders	4%
644	Speech Disorders	4%
645	Syncope	4%
646	Stupor	4%
647	Dysgraphia	4%
648	Presyncope	4%
649	Dyslalia	4%
650	Muscular Dystrophy	4%
651	Congenital nystagmus	4%
652	Orbital Myositis	4%
653	Diplopia	4%
654	Muscle Rigidity	4%
655	Muscle Spasticity	4%
656	Scotoma	4%
657	Photophobia	4%
658	Cogwheel Rigidity	4%
659	Hemifacial Spasm	4%
660	Amaurosis	4%
661	Blindness	4%
662	Nuchal Rigidity	4%
663	Reye Syndrome	3.9%
664	Neuroaspergillosis	3.9%
665	Pyomyositis	3.9%
666	Intracranial Embolism and Thrombosis	3.9%
667	Hepatic Encephalopathy	3.9%
668	Agnosia	3.9%
669	Apraxias	3.9%
670	Hallucinations	3.9%
671	Hemianopsia	3.9%
672	Hyperacusis	3.9%
673	Tinnitus	3.9%
674	Visual Agnosia	3.9%
675	Anosognosia	3.9%
676	Wernicke-Korsakoff Syndrome	3.9%
677	Phonophobia	3.9%
678	Hearing Loss	3.9%
679	Sarcopenia	3.9%
680	Myalgia	3.8%
681	Neuronal Ceroid-Lipofuscinoses	3.8%
682	Hyperprolactinemia	3.7%
683	Subclavian Steal Syndrome	3.7%
684	Aphasia	3.7%
685	Articulation Disorders	3.7%
686	Echolalia	3.7%
687	Stuttering	3.7%
688	Dysphasia	3.7%
689	Marijuana Abuse	3.6%
690	Opioid-Related Disorders	3.6%
691	Nicotine Dependence	3.6%
692	Opioid abuse	3.6%
693	Phencyclidine Abuse	3.6%
694	Substance Abuse, Intravenous	3.6%
695	Substance Withdrawal Syndrome	3.6%
696	Tobacco Use Disorder	3.6%
697	Alcohol-Related Disorders	3.6%
698	Amphetamine-Related Disorders	3.6%
699	Cocaine-Related Disorders	3.6%
700	Pseudorabies	3.6%
701	Dysarthria	3.6%
702	Gambling	3.5%
703	Premature Ejaculation	3.5%
704	Erectile dysfunction	3.5%
705	Aicardi's syndrome	3.5%
706	Toxoplasmosis, Congenital	3.5%
707	Eye Burns	3.4%
708	Waterhouse-Friderichsen Syndrome	3.4%
709	Color blindness	3.4%
710	Malaria, Cerebral	3.4%
711	Hoarseness	3.4%
712	Cri-du-Chat Syndrome	3.4%
713	Down Syndrome	3.4%
714	Brain Diseases, Metabolic, Inborn	3.4%
715	Trisomy 21	3.4%
716	Carotid Stenosis	3.4%
717	Intracranial Aneurysm	3.4%
718	Welander Distal Myopathy	3.4%
719	POEMS Syndrome	3.4%
720	Neurocysticercosis	3.4%
721	Cockayne Syndrome	3.4%
722	Meningioma	3.4%
723	Williams Syndrome	3.4%
724	Amaurosis Fugax	3.4%
725	Blindness, Cortical	3.4%
726	Intracranial Arteriosclerosis	3.4%
727	Cerebral Atherosclerosis	3.4%
728	Rett Syndrome	3.4%
729	Subarachnoid Hemorrhage	3.4%
730	Cerebral Arteriosclerosis	3.4%
731	Cerebral Hemorrhage	3.4%
732	Cerebral Thrombosis	3.4%
733	Intracranial Embolism	3.4%
734	Intracranial Thrombosis	3.4%
735	Microcephaly	3.4%
736	Macrocephaly	3.4%
737	Deafness	3.4%
738	Hearing Loss, Sudden	3.4%
739	Gerstmann Syndrome	3.4%
740	Hearing Loss, Bilateral	3.4%
741	Hearing Loss, High-Frequency	3.4%
742	Hearing Loss, Mixed Conductive-Sensorineural	3.4%
743	Prosopagnosia	3.4%
744	Apraxia, Ideomotor	3.4%
745	Charles Bonnet Syndrome	3.4%
746	Hearing Loss, Unilateral	3.4%
747	Complete Hearing Loss	3.4%
748	Alien Hand Syndrome	3.4%
749	Deaf Mutism	3.4%
750	Neurosyphilis	3.4%
751	Hypokalemic periodic paralysis	3.4%
752	Porencephaly	3.4%
753	Menkes Kinky Hair Syndrome	3.3%
754	Acromegaly	3.2%
755	Cerebral Amyloid Angiopathy	3.2%
756	Sinus Thrombosis, Intracranial	3.1%
757	Holoprosencephaly	3.1%
758	Neonatal Abstinence Syndrome	3.1%
759	Dermatomyositis	3%
760	Prader-Willi Syndrome	3%
761	Corneal Scar	3%
762	Cavernous Sinus Thrombosis	3%
763	Sagittal Sinus Thrombosis	3%
764	Phantom pain	3%
765	Phantom Limb Pain	3%
766	Psychoses, Alcoholic	3%
767	Lyme Neuroborreliosis	3%
768	Muscular Dystrophy, Duchenne	3%
769	Dyspareunia	3%
770	Carotid Artery Thrombosis	3%
771	Combat Disorders	2.8%
772	Dysthymic Disorder	2.8%
773	Hysteria	2.8%
774	Schizophrenia, Catatonic	2.8%
775	Schizophrenia, Disorganized	2.8%
776	Post-Traumatic Stress Disorder	2.8%
777	Attention Deficit Disorder	2.8%
778	Seasonal Affective Disorder	2.8%
779	Conduct Disorder	2.8%
780	Social Communication Disorder	2.8%
781	Psychological Trauma	2.8%
782	Hoarding Disorder	2.8%
783	Phonological Disorder	2.8%
784	Corneal Perforation	2.8%
785	Kernicterus	2.7%
786	Fabry Disease	2.7%
787	Nelson Syndrome	2.6%
788	Fragile X Syndrome	2.6%
789	Enuresis	2.6%
790	Rubinstein-Taybi Syndrome	2.5%
791	Prolactinoma	2.4%
792	Growth Hormone-Secreting Pituitary Adenoma	2.4%
793	Galactosemias	2.3%
794	Urea Cycle Disorders, Inborn	2.3%
795	Tyrosinemias	2.3%
796	Alcohol Use Disorder	2.3%
797	Alcoholic Intoxication	2.3%
798	Heroin Dependence	2.3%
799	Morphine Dependence	2.3%
800	Alcohol abuse	2.3%
801	Depression, Postpartum	2.3%
802	Premenstrual Dysphoric Disorder	2.3%
803	Homocystinuria	2.1%
804	Leigh Disease	2.1%
805	Autistic Disorder	2.1%
806	Asperger Syndrome	2.1%
807	Binge Drinking	2%
808	Carbamoyl-Phosphate Synthase I Deficiency Disease	2%
809	Mucopolysaccharidosis II	1.9%
810	Glycogen storage disease type II	1.8%
811	Diurnal Enuresis	1.7%
812	Zellweger Syndrome	1.7%
813	Gaucher Disease	1.6%
814	Tay-Sachs Disease	1.5%
815	Niemann-Pick Disease, Type C	1.4%

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