MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Decerebrate State

(UMLS:C0011103)

Definition:: A condition characterized by abnormal posturing of the limbs that is associated with injury to the brainstem. This may occur as a clinical manifestation or induced experimentally in animals. The extensor reflexes are exaggerated leading to rigid extension of the limbs accompanied by hyperreflexia and opisthotonus. This condition is usually caused by lesions which occur in the region of the brainstem that lies between the red nuclei and the vestibular nuclei. In contrast, decorticate rigidity is characterized by flexion of the elbows and wrists with extension of the legs and feet. The causative lesion for this condition is located above the red nuclei and usually consists of diffuse cerebral damage. (From Adams et al., Principles of Neurology, 6th ed, p358)
UMLS ID:: C0011103
MeSH ID:: D003655

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.597.305

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.888.592.298

Synonym(s)

Decerebrate State

Decerebrate posturing

Decerebrate rigidity

decerebrate rigidity

decerebrate rigidity was noted

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Baclofen		19577646	CTD
2	Methotrexate		4739170	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hemiparesis	44.8%
2	Meningism	44.8%
3	Paresis	44.8%
4	Seizures	44.8%
5	Sensation Disorders	44.8%
6	Complex partial seizures	44.8%
7	Monoparesis	44.8%
8	Gait Disorders, Neurologic	44.8%
9	Neuromuscular Manifestations	44.8%
10	Asterixis	39.7%
11	Ballismus	39.7%
12	Gait Ataxia	39.4%
13	Pupil Disorders	37.1%
14	Neurobehavioral Manifestations	37.1%
15	Vertigo	35.4%
16	Akathisia	33.8%
17	Restlessness	33.8%
18	Psychomotor Agitation	33.8%
19	Anosmia	32.8%
20	Ataxia	32.8%
21	Athetosis	32.8%
22	Catalepsy	32.8%
23	Dystonia	32.8%
24	Hemiplegia	32.8%
25	Locked-In Syndrome	32.8%
26	Muscle Hypertonia	32.8%
27	Muscle hypotonia	32.8%
28	Myoclonus	32.8%
29	Myotonia	32.8%
30	Paraplegia	32.8%
31	Pseudobulbar Palsy	32.8%
32	Quadriplegia	32.8%
33	Spasm	32.8%
34	Spastic Paraplegia	32.8%
35	Status Epilepticus	32.8%
36	Taste Disorders	32.8%
37	Tremor	32.8%
38	Monoplegia	32.8%
39	Hypokinesia	32.8%
40	Paraparesis	32.8%
41	Bradykinesia	32.8%
42	Waxy flexibility	32.8%
43	Action Tremor	32.8%
44	Resting Tremor	32.8%
45	Dysosmia	32.8%
46	Quadriparesis	32.8%
47	Olfaction Disorders	32.8%
48	Myokymia	32.8%
49	Somatosensory Disorders	32.8%
50	Hyperkinesia	32.8%
51	Intention tremor	32.8%
52	Gait Apraxia	32%
53	Psychophysiologic Disorders	31.8%
54	Voice Disorders	30.2%
55	Voice Disturbance	30.2%
56	Sleep Wake Disorders	29.4%
57	Chorea	29.3%
58	Muscular Atrophy	28.9%
59	Orthostatic intolerance	28.8%
60	Alice in Wonderland Syndrome	28.3%
61	Abdominal Pain	27.7%
62	Alexia	27.3%
63	Vision Disorders	27.3%
64	Metamorphopsia	27.3%
65	Dyslexia	27.3%
66	Visual Impairment	27.3%
67	Dysgeusia	27%
68	Formication	27%
69	Hyperalgesia	27%
70	Hyperesthesia	27%
71	Hypesthesia	27%
72	Language Disorders	27%
73	Numbness	27%
74	Paresthesia	27%
75	Paraparesis, Spastic	27%
76	Trismus	27%
77	Epilepsia Partialis Continua	27%
78	Hypogeusia	27%
79	Brown-Sequard Syndrome	27%
80	Lockjaw	27%
81	Allodynia	27%
82	Ageusia	27%
83	Anisocoria	26.5%
84	Confusion	26.5%
85	Facial paralysis	26.5%
86	Lethargy	26.5%
87	Memory Disorders	26.5%
88	Muscle Cramp	26.5%
89	Perceptual Disorders	26.5%
90	Psychomotor Disorders	26.5%
91	Tonic Pupil	26.5%
92	Anhedonia	26.5%
93	Disorientation	26.5%
94	Facial Paresis	26.5%
95	Memory Loss	26.5%
96	Hemisensory Neglect	26.5%
97	Dysacusis	26.5%
98	Respiratory Paralysis	26.2%
99	Tetany	26%
100	Muscle Weakness	25.7%
101	Ophthalmoplegia	25.4%
102	External Ophthalmoplegia	25.4%
103	Phantom pain	24.9%
104	Phantom Limb Pain	24.9%
105	Reflex, Abnormal	24.9%
106	Hyporeflexia	24.9%
107	Hyperreflexia	24.9%
108	Cerebellar Ataxia	24.8%
109	Torticollis	24.8%
110	Tardive Dyskinesia	24.3%
111	Cerebrospinal Fluid Otorrhea	24.3%
112	Cerebrospinal Fluid Rhinorrhea	24.3%
113	Neurogenic Inflammation	24.1%
114	Agraphia	24.1%
115	Anomia	24.1%
116	Cluttering	24.1%
117	Language Development Disorders	24.1%
118	Speech Disorders	24.1%
119	Syncope	24.1%
120	Stupor	24.1%
121	Dysgraphia	24.1%
122	Presyncope	24.1%
123	Dyslalia	24.1%
124	Back Pain	23.6%
125	Neck Pain	23.6%
126	Chest Pain	23.6%
127	Dizziness	23.6%
128	Facial Pain	23.6%
129	Flank Pain	23.6%
130	Headache	23.6%
131	Pain, Intractable	23.6%
132	Pelvic Pain	23.6%
133	Chronic pain	23.6%
134	Lightheadedness	23.6%
135	Pain, Referred	23.6%
136	Throbbing Headache	23.6%
137	Labor Pain	23.6%
138	Cancer Pain	23.6%
139	Nociceptive Pain	23.6%
140	Sarcopenia	23.4%
141	Aphasia	22.7%
142	Articulation Disorders	22.7%
143	Echolalia	22.7%
144	Stuttering	22.7%
145	Dysphasia	22.7%
146	Horner Syndrome	22.7%
147	Neuralgia	22.7%
148	Neuropathic pain	22.7%
149	Persistent Vegetative State	22.5%
150	Eye pain	22.4%
151	Consciousness Disorders	22.3%
152	Mental Retardation	22.3%
153	Depressed Level of Consciousness	22.3%
154	Mental deficiency	22.3%
155	Intellectual Disability	22.3%
156	Catatonia	22%
157	Dyskinesia, Drug-Induced	22%
158	Dysarthria	22%
159	Abdomen, Acute	22%
160	Vocal Cord Paralysis	22%
161	Diplopia	21.9%
162	Muscle Rigidity	21.9%
163	Muscle Spasticity	21.9%
164	Scotoma	21.9%
165	Photophobia	21.9%
166	Cogwheel Rigidity	21.9%
167	Hemifacial Spasm	21.9%
168	Amaurosis	21.9%
169	Blindness	21.9%
170	Nuchal Rigidity	21.9%
171	Aphonia	21.8%
172	Renal Colic	21.8%
173	Dysphonia	21.8%
174	Agnosia	21.6%
175	Apraxias	21.6%
176	Hallucinations	21.6%
177	Hemianopsia	21.6%
178	Hyperacusis	21.6%
179	Tinnitus	21.6%
180	Visual Agnosia	21.6%
181	Anosognosia	21.6%
182	Wernicke-Korsakoff Syndrome	21.6%
183	Phonophobia	21.6%
184	Hearing Loss	21.6%
185	Amblyopia	21.6%
186	Hoarseness	21.5%
187	Ophthalmoplegic Migraine	21.4%
188	Polydipsia	21.1%
189	Pain, Postoperative	21%
190	Asthenia	20.9%
191	Body Temperature Changes	20.9%
192	Cyanosis	20.9%
193	Edema	20.9%
194	Failure to Thrive	20.9%
195	Fatigue	20.9%
196	Feminization	20.9%
197	Fetal Distress	20.9%
198	Motion Sickness	20.9%
199	Signs and Symptoms, Digestive	20.9%
200	Signs and Symptoms, Respiratory	20.9%
201	Skin Manifestations	20.9%
202	Chills	20.9%
203	Lassitude	20.9%
204	Pseudophakia	20.9%
205	Urological Manifestations	20.9%
206	Mobility Limitation	20.9%
207	Somnolence	20.9%
208	Progressive supranuclear palsy	20%
209	Low Back Pain	19.6%
210	Visceral Pain	19.6%
211	Amaurosis Fugax	19.3%
212	Blindness, Cortical	19.3%
213	Dyscalculia	19.3%
214	Deafness	19.2%
215	Hearing Loss, Sudden	19.2%
216	Gerstmann Syndrome	19.2%
217	Hearing Loss, Bilateral	19.2%
218	Hearing Loss, High-Frequency	19.2%
219	Hearing Loss, Mixed Conductive-Sensorineural	19.2%
220	Prosopagnosia	19.2%
221	Apraxia, Ideomotor	19.2%
222	Charles Bonnet Syndrome	19.2%
223	Hearing Loss, Unilateral	19.2%
224	Complete Hearing Loss	19.2%
225	Alien Hand Syndrome	19.2%
226	Deaf Mutism	19.2%
227	Pain	18.9%
228	Ache	18.9%
229	Alcohol Withdrawal Seizures	18.6%
230	Mutism	18.5%
231	Selective Mutism	18.5%
232	Amnesia	18.2%
233	Delirium	18.2%
234	Dissociative Amnesia	18.2%
235	Color blindness	18.2%
236	Global Amnesia	18.2%
237	Dysmenorrhea	18%
238	Failed Back Surgery Syndrome	18%
239	Sciatica	17.8%
240	Alexia, Pure	17.7%
241	Gastroparesis	17.6%
242	Amnesia, Transient Global	16.6%
243	Eye Manifestations	16.4%
244	Retrograde amnesia	16%
245	Amnesia, Anterograde	16%
246	Cardiac Output, High	15.8%
247	Myocardial Stunning	15.8%
248	Reticulocytosis	15.8%
249	Low Cardiac Output Syndrome	15.8%
250	Auditory Perceptual Disorders	15.5%
251	Intermittent Claudication	15.4%
252	Akathisia, Drug-Induced	15.3%
253	Brain Death	15.2%
254	Sleep Deprivation	15.1%
255	Toothache	14.9%
256	Postoperative Nausea and Vomiting	14.7%
257	Cranial nerve diseases	14.6%
258	Demyelinating Diseases	14.6%
259	Demyelination	14.6%
260	Neuromuscular Diseases	14.6%
261	Chronobiology Disorders	14.6%
262	Metatarsalgia	14.5%
263	Multiple System Atrophy	14.1%
264	Mastodynia	14.1%
265	Motor Neuron Disease	14%
266	Breakthrough Pain	14%
267	Anorexia	13.6%
268	Anoxia	13.6%
269	Constipation	13.6%
270	Diarrhea	13.6%
271	Dyspepsia	13.6%
272	Eructation	13.6%
273	Fever	13.6%
274	Flatulence	13.6%
275	Flushing	13.6%
276	Halitosis	13.6%
277	Heartburn	13.6%
278	Hiccough	13.6%
279	Hypercalciuria	13.6%
280	Hypercapnia	13.6%
281	Hyperphagia	13.6%
282	Nausea	13.6%
283	Pallor	13.6%
284	Vomiting	13.6%
285	Hypocapnia	13.6%
286	Dyschezia	13.6%
287	Hypoxia	13.6%
288	Hyperoxia	13.6%
289	Lower Urinary Tract Symptoms	13.6%
290	Hypoxemia	13.6%
291	Urinoma	13.6%
292	jaundice	13.6%
293	Stiff-Person Syndrome	12.6%
294	Subacute Combined Degeneration	12.6%
295	Coma, Post-Head Injury	12.5%
296	Hypergammaglobulinemia	12.5%
297	Opsoclonus-Myoclonus Syndrome	12.3%
298	Meningoencephalitis	12.2%
299	Pathological Conditions, Anatomical	12.2%
300	Spinal Muscular Atrophy	12.2%
301	Progressive Muscular Atrophy	12.2%
302	Encephalomyelitis	12.1%
303	Prion Diseases	12.1%
304	Autonomic Dysreflexia	12.1%
305	Complex Regional Pain Syndromes	12.1%
306	Jet Lag Syndrome	12%
307	Polyradiculoneuropathy	12%
308	Polyradiculoneuritis	12%
309	Musculoskeletal Pain	11.9%
310	Parkinson Disease	11.8%
311	Arthralgia	11.7%
312	Polyarthralgia	11.7%
313	Angina Pectoris	11.7%
314	Ocular Motility Disorders	11.6%
315	Cyclophoria	11.6%
316	Amyotrophic Lateral Sclerosis	11.5%
317	Trauma, Nervous System	11.3%
318	Striatonigral Degeneration	11.3%
319	Restless Legs Syndrome	11.3%
320	Eye Hemorrhage	11.3%
321	Myalgia	11.2%
322	Marchiafava-Bignami Disease	11.1%
323	Hemoptysis	11%
324	Nervous System Neoplasms	10.9%
325	Neurotoxicity Syndromes	10.9%
326	Ecchymosis	10.8%
327	Petechiae	10.8%
328	Purpura	10.8%
329	Lewy Body Disease	10.7%
330	Guillain-Barre Syndrome	10.7%
331	Causalgia	10.7%
332	Angina, Unstable	10.4%
333	Kearns-Sayre syndrome	10.4%
334	Apnea	10.3%
335	Cheyne-Stokes Respiration	10.3%
336	Dyspnea	10.3%
337	Hyperventilation	10.3%
338	Mouth Breathing	10.3%
339	Pruritus	10.3%
340	Sneezing	10.3%
341	Erythema	10.3%
342	Necrolytic Migratory Erythema	10.3%
343	Tachypnea	10.3%
344	Edema, Cardiac	10.2%
345	Mental Fatigue	10.2%
346	Hirsutism	10.2%
347	Myelitis	10.2%
348	Progressive bulbar palsy	10.2%
349	Hypoventilation	10.2%
350	Bulbar palsy	10.2%
351	Bulimia	10.1%
352	Dandy-Walker Syndrome	10.1%
353	Dysuria	10.1%
354	Fever of Unknown Origin	10.1%
355	Nocturia	10.1%
356	Snoring	10.1%
357	Prostatism	10.1%
358	Leukoencephalitis, Acute Hemorrhagic	10.1%
359	Pneumocephalus	10.1%
360	Poliomyelitis	10.1%
361	Body Weight Changes	10%
362	Jaundice, Obstructive	10%
363	Spinal Cord Injuries	10%
364	Miller Fisher Syndrome	10%
365	Angina Pectoris, Variant	9.7%
366	Peripheral Nerve Injuries	9.7%
367	Shy-Drager Syndrome	9.7%
368	Myasthenia Gravis	9.6%
369	Shoulder Pain	9.6%
370	Epidural Abscess	9.4%
371	Olfactory Nerve Injuries	9.4%
372	Ataxia Telangiectasia	9.4%
373	MPTP Poisoning	9.3%
374	Brain Diseases	9.3%
375	Dysautonomia	9.3%
376	Meningitis	9.3%
377	Movement Disorders	9.3%
378	Pachymeningitis	9.3%
379	Spinal Cord Diseases	9.3%
380	Vagus Nerve Disorder	9.3%
381	Glossopharyngeal Neuralgia	9.3%
382	Abducens Nerve Diseases	9.3%
383	Heavy Metal Poisoning, Nervous System	9.3%
384	Neuromuscular Junction Diseases	9.3%
385	Tauopathies	9.3%
386	Trochlear Nerve Diseases	9.3%
387	Peripheral Nervous System Diseases	9.3%
388	Myelitis, Transverse	9.3%
389	Reflex Sympathetic Dystrophy	9.2%
390	Subdural Effusion	9.2%
391	Parkinsonian Disorders	9.2%
392	Nocturnal Myoclonus Syndrome	9.2%
393	Epistaxis	9.2%
394	Encephalomyelitis, Acute Disseminated	9.1%
395	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	9.1%
396	Rett Syndrome	8.9%
397	Neuromyelitis Optica	8.9%
398	Dystonia Musculorum Deformans	8.9%
399	Neuroleptic Malignant Syndrome	8.8%
400	Myelinolysis, Central Pontine	8.8%
401	Body Weight	8.5%
402	Vascular Remodeling	8.5%
403	Lambert-Eaton Myasthenic Syndrome	8.4%
404	Cri-du-Chat Syndrome	8.4%
405	Down Syndrome	8.4%
406	Emaciation	8.4%
407	Trisomy 21	8.4%
408	Chronic Fatigue Syndrome	8.3%
409	Meige Syndrome	8.3%
410	Brachial Plexus Neuritis	8.3%
411	Neuralgic Amyotrophy	8.3%
412	Cerebral Ventriculitis	8.3%
413	Williams Syndrome	8.3%
414	Epilepsy, Post-Traumatic	8.2%
415	Sleep Disorders, Circadian Rhythm	8.2%
416	Pleural Rub	8.2%
417	Rales	8.2%
418	Respiratory Sounds	8.2%
419	Rhonchi	8.2%
420	Stridor	8.2%
421	Wheezing	8.2%
422	Livedo Reticularis	8.1%
423	Brain Injuries	8.1%
424	Facial Nerve Injuries	8.1%
425	Brain Neoplasms	8.1%
426	Multiple Sclerosis	8.1%
427	Oliguria	8.1%
428	Polyuria	8.1%
429	Proteinuria	8.1%
430	Spinal Cord Neoplasms	8.1%
431	Leukoencephalopathy, Progressive Multifocal	8%
432	Hematemesis	8%
433	Purpura Fulminans	7.9%
434	Underweight	7.9%
435	Overweight	7.9%
436	Botulism	7.9%
437	Central Nervous System Cysts	7.9%
438	Tarsal Tunnel Syndrome	7.9%
439	Cauda Equina Syndrome	7.9%
440	Posterior Leukoencephalopathy Syndrome	7.9%
441	Posterior reversible encephalopathy syndrome	7.9%
442	Lafora Disease	7.8%
443	Unverricht-Lundborg Syndrome	7.8%
444	Morning Sickness	7.7%
445	Cerebellar Neoplasms	7.6%
446	Limbic Encephalitis	7.6%
447	Huntington Disease	7.6%
448	Cachexia	7.5%
449	Scrapie	7.5%
450	Central Cord Syndrome	7.5%
451	Weight Gain	7.5%
452	Myoclonic Epilepsy	7.4%
453	Epilepsy, Temporal Lobe	7.4%
454	Epilepsy, Rolandic	7.4%
455	Benign Rolandic Epilepsy	7.4%
456	Lupus Vasculitis, Central Nervous System	7.4%
457	Presenile dementia	7.4%
458	Senile dementia	7.4%
459	Meningitis, Bacterial	7.4%
460	Meningitis, Fungal	7.4%
461	Acrodynia	7.3%
462	Charcot-Marie-Tooth Disease	7.3%
463	Central Nervous System Infection	7.3%
464	Myopathy	7.3%
465	Optic Neuropathy	7.3%
466	Prader-Willi Syndrome	7.1%
467	Myasthenia Gravis, Autoimmune, Experimental	7%
468	Facial Nerve Diseases	7%
469	Craniocerebral Trauma	7%
470	Parasomnia	7%
471	Dyssomnias	7%
472	Juvenile Myoclonic Epilepsy	7%
473	Myoclonic Epilepsies, Progressive	7%
474	Dementia, Vascular	7%
475	Ascites	7%
476	Calculi	7%
477	Fibrosis	7%
478	Gliosis	7%
479	Growth Disorders	7%
480	Hemorrhage	7%
481	Hernia	7%
482	Hyperbilirubinemia	7%
483	Hyperplasia	7%
484	Hypertrophy	7%
485	Hypomenorrhea	7%
486	Inflammation	7%
487	Intraoperative Complications	7%
488	Ischemia	7%
489	Lithiasis	7%
490	Malacoplakia	7%
491	Menstruation Disturbances	7%
492	Metaplasia	7%
493	Nails, Malformed	7%
494	Nerve Degeneration	7%
495	Ochronosis	7%
496	Polymenorrhea	7%
497	polyps	7%
498	Postoperative Complications	7%
499	Rupture, Spontaneous	7%
500	Sclerosis	7%
501	Shock	7%
502	Ulcer	7%
503	Enterocele	7%
504	Hyperammonemia	7%
505	Hyperamylasemia	7%
506	Teratogenesis	7%
507	Atheroma	7%
508	Cardiac Death	7%
509	Hypovolemia	7%
510	Hyperuricemia	7%
511	Leukoaraiosis	7%
512	Stenosis	7%
513	Facial asymmetry	7%
514	Dysbacteriosis	7%
515	Delayed Graft Function	7%
516	Cirrhosis	7%
517	Plaque, Amyloid	7%
518	Plaque, Atherosclerotic	7%
519	Neointima	7%
520	Dysbiosis	7%
521	Brain Hemorrhage, Traumatic	7%
522	Vestibulocochlear Nerve Diseases	6.9%
523	Hydranencephaly	6.9%
524	Neural Tube Defects	6.9%
525	Tethered Cord Syndrome	6.9%
526	Central Nervous System Neoplasms	6.9%
527	Iniencephaly	6.9%
528	Craniorachischisis	6.9%
529	Exencephaly	6.9%
530	Septo-Optic Dysplasia	6.9%
531	Cortical Dysplasia	6.9%
532	Malformations of Cortical Development	6.9%
533	Sweating, Gustatory	6.8%
534	Auriculotemporal Syndrome	6.8%
535	Friedreich Ataxia	6.8%
536	Akinetic Mutism	6.8%
537	Anoxic Encephalopathy	6.8%
538	Arachnoiditis	6.8%
539	Basal Ganglia Diseases	6.8%
540	Brain Damage, Chronic	6.8%
541	Cerebellar Diseases	6.8%
542	Encephalitis	6.8%
543	Encephalomalacia	6.8%
544	Epilepsy	6.8%
545	Gagging	6.8%
546	Hydrocephalus	6.8%
547	Congenital Hydrocephalus	6.8%
548	Hypothalamic Diseases	6.8%
549	Aseptic Meningitis	6.8%
550	Neuritis	6.8%
551	Polyneuritis	6.8%
552	Radiculitis	6.8%
553	Syringomyelia	6.8%
554	Thalamic Diseases	6.8%
555	Intracranial Hypertension	6.8%
556	Polyneuropathy	6.8%
557	Mononeuritis	6.8%
558	Aura	6.8%
559	Leukoencephalopathy	6.8%
560	Essential Tremor	6.8%
561	Neuroaxonal Dystrophies	6.8%
562	Familial Tremor	6.8%
563	Headache Disorders	6.8%
564	Mononeuropathies	6.8%
565	Intracranial Hypotension	6.8%
566	Brachial Plexus Neuropathies	6.8%
567	Radiculopathy	6.8%
568	Mononeuropathy Multiplex	6.8%
569	Nerve Root Compression	6.8%
570	Brain Edema	6.8%
571	Brain Hypoxia	6.8%
572	Aqueductal Stenosis	6.8%
573	Pneumorrhachis	6.8%
574	Writer's Cramp	6.8%
575	Canavan Disease	6.8%
576	Alexander Disease	6.8%
577	Brain Abscess	6.8%
578	Infarction	6.8%
579	Postoperative Hemorrhage	6.8%
580	Shock, Hemorrhagic	6.8%
581	Systemic Inflammatory Response Syndrome	6.8%
582	Incisional hernia	6.8%
583	Meningocele	6.7%
584	Encephalocele	6.7%
585	Creutzfeldt-Jakob disease	6.7%
586	Basal Ganglia Cerebrovascular Disease	6.7%
587	Brain Injuries, Diffuse	6.6%
588	Traumatic Brain Injury	6.6%
589	Supratentorial Neoplasms	6.6%
590	Multiple Sclerosis, Chronic Progressive	6.6%
591	Multiple Sclerosis, Relapsing-Remitting	6.6%
592	Tuberculosis, Meningeal	6.5%
593	Basal Ganglia Hemorrhage	6.4%
594	Fragile X Syndrome	6.3%
595	Carpal Tunnel Syndrome	6.3%
596	Vascular Headaches	6.3%
597	Vasculitis, Central Nervous System	6.3%
598	Hyperemesis Gravidarum	6.3%
599	neurofibroma	6.3%
600	Hypoxia-Ischemia, Brain	6.3%
601	Hematoma, Subdural	6.2%
602	Hematoma, Epidural, Cranial	6.2%
603	Carotid Artery Injuries	6.2%
604	Waterhouse-Friderichsen Syndrome	6.1%
605	Myotonia Congenita	6.1%
606	Fetal Hypoxia	6.1%
607	Paraneoplastic Cerebellar Degeneration	6.1%
608	Neuritis, Autoimmune, Experimental	6.1%
609	Dyspnea, Paroxysmal	6%
610	Urinary Incontinence	6%
611	Putaminal Hemorrhage	6%
612	Albuminuria	5.9%
613	Hemoglobinuria	5.9%
614	Cubital Tunnel Syndrome	5.9%
615	Diffuse Axonal Injury	5.9%
616	Adrenoleukodystrophy	5.9%
617	Brain Stem Neoplasms	5.9%
618	Tuberous Sclerosis	5.9%
619	Thrombocytopenic purpura	5.8%
620	Pituitary Adenoma	5.8%
621	Pituitary Neoplasms	5.8%
622	Brain Concussion	5.7%
623	Myotonic Dystrophy	5.7%
624	Purpura, Hyperglobulinemic	5.7%
625	Cerebral Palsy	5.6%
626	Epilepsies, Partial	5.6%
627	Epilepsy, Generalized	5.6%
628	Pseudotumor Cerebri	5.6%
629	Sciatic Neuropathy	5.6%
630	Hypertensive Encephalopathy	5.6%
631	Ulnar Neuropathies	5.6%
632	Lesion of Sciatic Nerve	5.6%
633	Simple Partial Seizures	5.6%
634	Epilepsy, Reflex	5.6%
635	Ulnar Neuritis	5.6%
636	Radial nerve compression	5.6%
637	Radial Tunnel Syndrome	5.6%
638	Peroneal Neuropathies	5.6%
639	Radial Neuropathy	5.6%
640	Median Neuropathy	5.6%
641	Sciatic Nerve Palsy	5.6%
642	Femoral Neuropathy	5.6%
643	Tibial Neuropathy	5.6%
644	Ulnar Nerve Palsy	5.6%
645	Postural Orthostatic Tachycardia Syndrome	5.6%
646	Radial nerve palsy	5.6%
647	Headache Disorders, Primary	5.6%
648	Headache Disorders, Secondary	5.6%
649	Medication overuse headache	5.6%
650	Birth Weight	5.6%
651	Leukomalacia, Periventricular	5.6%
652	Paraneoplastic Encephalomyelitis	5.6%
653	Choroid Plexus Papilloma	5.5%
654	Rubinstein-Taybi Syndrome	5.5%
655	Hematoma, Subdural, Intracranial	5.5%
656	Hematoma, Subdural, Chronic	5.5%
657	Hematoma, Subdural, Acute	5.5%
658	Uveomeningoencephalitic Syndrome	5.5%
659	Hepatolenticular Degeneration	5.5%
660	Cyst	5.5%
661	Extravasation of Diagnostic and Therapeutic Materials	5.5%
662	Neoplastic Processes	5.5%
663	Sturge-Weber Syndrome	5.4%
664	Alcohol-Induced Disorders, Nervous System	5.4%
665	Toxoplasmosis, Cerebral	5.3%
666	Leukoplakia	5.3%
667	Necrosis	5.3%
668	Granulomatosis, Orofacial	5.3%
669	Pigmentation Disorders	5.3%
670	Respiratory Aspiration	5.3%
671	Airway Remodeling	5.3%
672	Optic Nerve Glioma	5.3%
673	Meningitis, Cryptococcal	5.2%
674	Meningitis, Listeria	5.2%
675	Meningitis, Haemophilus	5.2%
676	Meningitis, Pneumococcal	5.2%
677	Frontotemporal dementia	5.2%
678	Acantholysis	5.2%
679	Brain Diseases, Metabolic	5.2%
680	Cerebrovascular Disorders	5.2%
681	Chromosome Aberrations	5.2%
682	Dehydration	5.2%
683	Granuloma	5.2%
684	Leukocytosis	5.2%
685	Myositis	5.2%
686	Optic Atrophy	5.2%
687	Optic Neuritis	5.2%
688	Papilledema	5.2%
689	Strabismus	5.2%
690	Tolosa-Hunt Syndrome	5.2%
691	Pleocytosis	5.2%
692	Cerebrovascular Insufficiency	5.2%
693	Isaacs syndrome	5.2%
694	Arsenic Poisoning	5.2%
695	Dementia	5.2%
696	Myotonic Disorders	5.2%
697	Ventricular Remodeling	5.2%
698	Central Nervous System Fungal Infections	5.2%
699	Conus Medullaris Syndrome	5.2%
700	Myasthenic Syndromes, Congenital	5.2%
701	Spinal Cord Vascular Diseases	5.2%
702	Alopecia	5.1%
703	Androgenetic Alopecia	5.1%
704	Diabetic Neuropathies	5.1%
705	Facial Injuries	5.1%
706	Facial Neuralgia	5.1%
707	Diabetic Amyotrophy	5.1%
708	Diabetic Autonomic Neuropathy	5.1%
709	Sleep Talking	5.1%
710	Manganese Poisoning	5.1%
711	Sleep Disorders, Intrinsic	5.1%
712	Meningeal Neoplasms	5%
713	Meningomyelocele	5%
714	Spina Bifida	5%
715	Mercury Poisoning, Nervous System	5%
716	Lead Poisoning, Nervous System	5%
717	Vestibular Neuronitis	5%
718	Infarction, Middle Cerebral Artery	5%
719	Infarction, Anterior Cerebral Artery	5%
720	Infarction, Posterior Cerebral Artery	5%
721	Polyradiculopathy	5%
722	Post-Traumatic Headache	5%
723	Tension Headache	5%
724	Epilepsy, Complex Partial	5%
725	Migraine Disorders	5%
726	Abdominal Migraine	5%
727	Status Migrainosus	5%
728	Cervicogenic Headache	5%
729	Refsum Disease	5%
730	Pituitary Apoplexy	5%
731	Sudden infant death syndrome	5%
732	Vertebral Artery Dissection	5%
733	Subarachnoid Hemorrhage	5%
734	Cerebral Hemorrhage	5%
735	Urge Incontinence	4.9%
736	Brain Contusion	4.9%
737	Obesity	4.9%
738	Brain Infarction	4.9%
739	Subacute Sclerosing Panencephalitis	4.9%
740	Menkes Kinky Hair Syndrome	4.9%
741	Subarachnoid Hemorrhage, Traumatic	4.9%
742	Carotid Artery, Internal, Dissection	4.9%
743	Mitochondrial Encephalomyopathies	4.7%
744	Cluster Headache	4.7%
745	Migraine with Aura	4.7%
746	Familial Hemiplegic Migraine	4.7%
747	Chronic Paroxysmal Hemicrania	4.7%
748	SUNCT Syndrome	4.7%
749	Paroxysmal Hemicrania	4.7%
750	Purpura, Thrombotic Thrombocytopenic	4.7%
751	Menorrhagia	4.7%
752	Alstrom Syndrome	4.6%
753	Cerebral Infarction	4.6%
754	Brain Stem Infarctions	4.6%
755	Acute Disease	4.5%
756	Acute-Phase Reaction	4.5%
757	Amenorrhea	4.5%
758	Chronic disease	4.5%
759	Critical Illness	4.5%
760	Sudden death	4.5%
761	Fat necrosis	4.5%
762	Gangrene	4.5%
763	Graft Occlusion, Vascular	4.5%
764	Granuloma, Plasma Cell	4.5%
765	Hematoma	4.5%
766	Diaphragmatic Hernia	4.5%
767	Iatrogenic Disease	4.5%
768	Intestinal Polyps	4.5%
769	Multiple Organ Failure	4.5%
770	Oligomenorrhea	4.5%
771	Premenstrual syndrome	4.5%
772	Recurrence	4.5%
773	Retrograde Degeneration	4.5%
774	Retroperitoneal fibrosis	4.5%
775	Serositis	4.5%
776	Splenomegaly	4.5%
777	Subcutaneous Emphysema	4.5%
778	Surgical Wound Dehiscence	4.5%
779	Syndrome	4.5%
780	Wallerian Degeneration	4.5%
781	Pyogenic granuloma	4.5%
782	Exsanguination	4.5%
783	Disease Progression	4.5%
784	Seroma	4.5%
785	Premenstrual Tension	4.5%
786	Delayed Emergence from Anesthesia	4.5%
787	Infant Death	4.5%
788	Smith-Magenis syndrome	4.5%
789	Anastomotic Leak	4.5%
790	Intraoperative Awareness	4.5%
791	Dural Arteriovenous Fistula	4.5%
792	Chromosomal Instability	4.5%
793	Lateral Medullary Syndrome	4.5%
794	Hydrops Fetalis	4.4%
795	Pituitary Diseases	4.4%
796	Classical Lissencephalies and Subcortical Band Heterotopias	4.4%
797	Fetal Weight	4.4%
798	Mucopolysaccharidosis II	4.4%
799	Genomic Instability	4.3%
800	Hand-Arm Vibration Syndrome	4.3%
801	Thoracic Outlet Syndrome	4.3%
802	Tinea Pedis	4.2%
803	Carotid Artery Diseases	4.2%
804	Brain Ischemia	4.2%
805	Esotropia	4.2%
806	Exotropia	4.2%
807	Hypotension, Orthostatic	4.2%
808	Sleep Apnea Syndromes	4.2%
809	Cerebrovascular accident	4.2%
810	Polymyositis	4.2%
811	Kluver-Bucy Syndrome	4.2%
812	Vasospasm, Intracranial	4.2%
813	Spinal Cord Ischemia	4.2%
814	Intracranial Arterial Diseases	4.2%
815	Post-Exercise Hypotension	4.2%
816	Fibromyalgia	4.2%
817	Disorders of Excessive Somnolence	4.2%
818	Sleep Initiation and Maintenance Disorders	4.2%
819	Night Terrors	4.2%
820	Somnambulism	4.2%
821	Trigeminal Nerve Disorder	4.2%
822	Optic Neuropathy, Ischemic	4.2%
823	Transient Insomnia	4.2%
824	Sleep Paralysis	4.2%
825	Chronic Insomnia	4.2%
826	Anterior Ischemic Optic Neuropathy	4.2%
827	REM Sleep Behavior Disorder	4.2%
828	Central Nervous System Bacterial Infections	4.2%
829	Hypersomnia	4.2%
830	Medial Tibial Stress Syndrome	4.2%
831	Dermal Sinus	4.1%
832	Spina Bifida Cystica	4.1%
833	Spina Bifida Occulta	4.1%
834	Meningeal Carcinomatosis	4.1%
835	Lissencephaly	4.1%
836	Polymicrogyria	4.1%
837	Pachygyria	4.1%
838	Schizencephaly	4.1%
839	Lead Poisoning, Nervous System, Childhood	4.1%
840	Lead Poisoning, Nervous System, Adult	4.1%
841	Periventricular Nodular Heterotopia	4.1%
842	Tuberculosis, Central Nervous System	4.1%
843	West Nile Fever	4.1%
844	Facial Hemiatrophy	4.1%
845	Melkersson-Rosenthal Syndrome	4.1%
846	Mitochondrial Myopathies	4.1%
847	Moyamoya Disease	4.1%
848	Eosinophilia-Myalgia Syndrome	4.1%
849	Pediatric Obesity	4.1%
850	Diverticulum	4.1%
851	Sleep Bruxism	4.1%
852	Diverticulosis	4.1%
853	Neurofibrosarcoma	4.1%
854	Azotemia	4%
855	Anencephaly	4%
856	Amyloid Neuropathies, Familial	4%
857	MELAS Syndrome	4%
858	Giant Cell Arteritis	3.8%
859	Temporal Arteritis	3.8%
860	Empty Sella Syndrome	3.8%
861	Hyperpituitarism	3.8%
862	Hypopituitarism	3.8%
863	Hypophysitis	3.8%
864	Kernicterus	3.8%
865	Cerebral Arterial Diseases	3.7%
866	Vertebrobasilar Insufficiency	3.7%
867	Anterior Spinal Artery Syndrome	3.7%
868	Basilar Artery Stenosis	3.7%
869	Vertebral Artery Stenosis	3.7%
870	Sleep Apnea, Obstructive	3.7%
871	Sleep Apnea, Central	3.7%
872	Intracranial Hemorrhage, Hypertensive	3.7%
873	Transient Cerebral Ischemia	3.7%
874	Narcolepsy	3.7%
875	Trigeminal Neuralgia	3.7%
876	Kleine-Levin Syndrome	3.7%
877	Autoimmune thrombocytopenia	3.7%
878	Immune thrombocytopenic purpura	3.7%
879	Endotoxic shock	3.7%
880	Septic Shock	3.7%
881	Toxic Shock Syndrome	3.7%
882	Acoustic Neuroma	3.6%
883	Asphyxia	3.6%
884	Granuloma, Respiratory Tract	3.6%
885	Shock, Traumatic	3.6%
886	Respiratory Tract Fistula	3.6%
887	Hyperprolactinemia	3.5%
888	Subclavian Steal Syndrome	3.5%
889	Pick Disease of the Brain	3.5%
890	Cataplexy	3.5%
891	Optic Atrophy, Hereditary, Leber	3.5%
892	Eye Injuries	3.5%
893	Cardiotoxicity	3.5%
894	Disease susceptibility	3.4%
895	Duane Retraction Syndrome	3.4%
896	Fetal Death	3.4%
897	Foreign-Body Reaction	3.4%
898	Gastrointestinal Hemorrhage	3.4%
899	Cardiomegaly	3.4%
900	Hemarthrosis	3.4%
901	Hemoperitoneum	3.4%
902	Hemothorax	3.4%
903	Hepatomegaly	3.4%
904	Neoplasm Invasiveness	3.4%
905	Neoplasm Metastasis	3.4%
906	Neoplasm Recurrence, Local	3.4%
907	Parovarian Cyst	3.4%
908	Postpericardiotomy Syndrome	3.4%
909	Prosthesis Failure	3.4%
910	Reperfusion Injury	3.4%
911	Spermatocele	3.4%
912	Oral Fistula	3.4%
913	Injection Site Reaction	3.4%
914	Retrobulbar Hemorrhage	3.4%
915	Cutaneous Fistula	3.4%
916	Aseptic Necrosis of Bone	3.4%
917	Peritoneal Fibrosis	3.4%
918	Carcinogenesis	3.4%
919	Perinatal death	3.4%
920	Infusion site reaction	3.4%
921	Cardiac Hypertrophy	3.4%
922	Nephrogenic Fibrosing Dermopathy	3.4%
923	Corneal Endothelial Cell Loss	3.4%
924	Encapsulating Peritoneal Sclerosis	3.4%
925	Vasoplegia	3.4%
926	Suppuration	3.4%
927	Nephrogenic Systemic Fibrosis	3.4%
928	Metastasis	3.4%
929	Mobius Syndrome	3.4%
930	Bell Palsy	3.4%
931	Muscular Dystrophy	3.4%
932	Congenital nystagmus	3.4%
933	Orbital Myositis	3.4%
934	Sinus Arrhythmia	3.4%
935	Atrial Fibrillation	3.4%
936	Atrial Flutter	3.4%
937	Dental Pulp Necrosis	3.4%
938	Granuloma, Foreign-Body	3.4%
939	Mediastinal Emphysema	3.4%
940	Surgical Wound Infection	3.4%
941	Ventricular Fibrillation	3.4%
942	Ventricular Flutter	3.4%
943	Parasystole	3.4%
944	Paroxysmal atrial fibrillation	3.4%
945	Facies	3.4%
946	Bradycardia	3.4%
947	Embryo Loss	3.4%
948	Herpes Zoster Oticus	3.4%
949	Tissue Adhesions	3.4%
950	Colonic Polyps	3.4%
951	Familial Periodic Paralysis	3.4%
952	Hematoma, Epidural, Spinal	3.4%
953	Afferent Loop Syndrome	3.4%
954	Sex Chromosome Aberrations	3.4%
955	Short Bowel Syndrome	3.4%
956	Uterine hemorrhage	3.4%
957	Vaginal Fistula	3.4%
958	Rectocele	3.4%
959	No-Reflow Phenomenon	3.4%
960	Reye Syndrome	3.4%
961	Neuroaspergillosis	3.4%
962	Pyomyositis	3.4%
963	Intracranial Embolism and Thrombosis	3.3%
964	Hepatic Encephalopathy	3.3%
965	Chromosome Fragility	3.3%
966	Toxoplasmosis, Congenital	3%
967	Eye Burns	3%
968	Malaria, Cerebral	3%
969	Carotid Stenosis	3%
970	Intracranial Aneurysm	3%
971	Welander Distal Myopathy	3%
972	Neurocysticercosis	3%
973	Intracranial Arteriosclerosis	3%
974	Cerebral Atherosclerosis	3%
975	Cerebral Arteriosclerosis	3%
976	Cerebral Thrombosis	3%
977	Intracranial Embolism	3%
978	Intracranial Thrombosis	3%
979	Pseudorabies	2.9%
980	Acromegaly	2.8%
981	Neuronal Ceroid-Lipofuscinoses	2.8%
982	Drowning	2.8%
983	Sick Sinus Syndrome	2.8%
984	Trisomy	2.8%
985	Hematoma, Subdural, Spinal	2.8%
986	Brain Diseases, Metabolic, Inborn	2.8%
987	Cerebral Amyloid Angiopathy	2.8%
988	Nasal Polyps	2.8%
989	Sinus Thrombosis, Intracranial	2.8%
990	POEMS Syndrome	2.8%
991	Meningioma	2.8%
992	Microcephaly	2.8%
993	Macrocephaly	2.8%
994	Neurosyphilis	2.7%
995	Hypokalemic periodic paralysis	2.7%
996	Fetal Growth Retardation	2.7%
997	DNA Degradation, Necrotic	2.7%
998	Porencephaly	2.7%
999	Aneuploidy	2.7%
1000	Polyploidy	2.7%
1001	Microsatellite Instability	2.7%
1002	Heart Block	2.7%
1003	Tachycardia	2.7%
1004	Tachyarrhythmia	2.7%
1005	Cicatrix	2.7%
1006	Cavernous Sinus Thrombosis	2.7%
1007	Sagittal Sinus Thrombosis	2.7%
1008	Hematuria	2.7%
1009	Urinary Calculi	2.7%
1010	Granuloma Annulare	2.7%
1011	Chromosome Breakage	2.7%
1012	Shock, Cardiogenic	2.7%
1013	Biliary Fistula	2.6%
1014	Cross Infection	2.6%
1015	Gastric Fistula	2.6%
1016	Hyphema	2.6%
1017	Retinal Neovascularization	2.6%
1018	Septicemia	2.6%
1019	Vitreous Hemorrhage	2.6%
1020	Congenital diaphragmatic hernia	2.6%
1021	Sepsis	2.6%
1022	Vesicovaginal Fistula	2.6%
1023	Aicardi's syndrome	2.6%
1024	Dermatomyositis	2.5%
1025	Corneal Scar	2.5%
1026	Abscess	2.5%
1027	Dental Fistula	2.5%
1028	Empyema	2.5%
1029	Femur Head Necrosis	2.5%
1030	Fetal Resorption	2.5%
1031	Lymphatic Metastasis	2.5%
1032	Neoplasms, Unknown Primary	2.5%
1033	Oroantral Fistula	2.5%
1034	Peptic Ulcer Hemorrhage	2.5%
1035	Sudden Cardiac Death	2.5%
1036	Left Ventricular Hypertrophy	2.5%
1037	Leukemic Infiltration	2.5%
1038	Right Ventricular Hypertrophy	2.5%
1039	Premenstrual Dysphoric Disorder	2.5%
1040	Choroidal Neovascularization	2.5%
1041	Primary Graft Dysfunction	2.5%
1042	Neoplasm Micrometastasis	2.5%
1043	Cockayne Syndrome	2.5%
1044	Dumping Syndrome	2.5%
1045	Rectal Prolapse	2.5%
1046	Uterine Prolapse	2.5%
1047	Cicatrix, Hypertrophic	2.5%
1048	Vaginal Prolapse	2.5%
1049	Sinus Arrest, Cardiac	2.5%
1050	Alcohol Withdrawal Delirium	2.5%
1051	Muscular Dystrophy, Duchenne	2.5%
1052	Metrorrhagia	2.5%
1053	Carotid Artery Thrombosis	2.5%
1054	Wernicke Encephalopathy	2.4%
1055	AIDS Dementia Complex	2.4%
1056	Lyme Neuroborreliosis	2.3%
1057	Corneal Perforation	2.3%
1058	Giant Cell Epulis	2.3%
1059	Nelson Syndrome	2.2%
1060	Leukoplakia, Oral	2.2%
1061	Long QT Syndrome	2.2%
1062	Holoprosencephaly	2.2%
1063	Viremia	2.2%
1064	Parasitemia	2.2%
1065	Micronuclei, Chromosome-Defective	2.2%
1066	Umbilical hernia	2.1%
1067	Bronchial Fistula	2.1%
1068	Pancreatic Fistula	2.1%
1069	Retinal Hemorrhage	2.1%
1070	Choroid Hemorrhage	2%
1071	Intestinal Fistula	2%
1072	Melena	2%
1073	Gastroschisis	2%
1074	Enterocutaneous Fistula	2%
1075	Postpartum Hemorrhage	2%
1076	Salivary Gland Fistula	2%
1077	Prolactinoma	2%
1078	Growth Hormone-Secreting Pituitary Adenoma	2%
1079	Cystocele	2%
1080	Gingival Hemorrhage	2%
1081	Keloid	2%
1082	Monosomy	2%
1083	Tetraploidy	2%
1084	Stillbirth	2%
1085	Adams-Stokes Syndrome	2%
1086	Atrioventricular Block	2%
1087	Bundle-Branch Block	2%
1088	Atrial Premature Complexes	2%
1089	Sinoatrial Block	2%
1090	Tachycardia, Paroxysmal	2%
1091	Supraventricular tachycardia	2%
1092	Tachycardia, Ventricular	2%
1093	Tachycardia, Reciprocating	2%
1094	Fabry Disease	2%
1095	Eosinophilic Granuloma	1.9%
1096	Galactosemias	1.8%
1097	Urea Cycle Disorders, Inborn	1.8%
1098	Tyrosinemias	1.8%
1099	Bacteremia	1.7%
1100	Cellulitis	1.7%
1101	Cell Transformation, Viral	1.7%
1102	Fungemia	1.7%
1103	Homocystinuria	1.6%
1104	Romano-Ward Syndrome	1.6%
1105	Tachycardia, Atrioventricular Nodal Reentry	1.6%
1106	Tachycardia, Ectopic Atrial	1.6%
1107	Tachycardia, Ectopic Junctional	1.6%
1108	Sinus Tachycardia	1.6%
1109	Torsades de Pointes	1.6%
1110	Accelerated Idioventricular Rhythm	1.6%
1111	Leigh Disease	1.6%
1112	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.5%
1113	Endotoxemia	1.5%
1114	Granuloma, Laryngeal	1.5%
1115	Myocardial Reperfusion Injury	1.4%
1116	Urinary Bladder Fistula	1.4%
1117	Rectal Fistula	1.4%
1118	Anal Fistula	1.4%
1119	Glycogen storage disease type II	1.4%
1120	Zellweger Syndrome	1.2%
1121	Arteriovenous fistula	1.2%
1122	Philadelphia Chromosome	1.2%
1123	Gaucher Disease	1.2%
1124	Tay-Sachs Disease	1.2%
1125	Kidney Calculi	1.1%
1126	Ureteral Calculi	1.1%
1127	Niemann-Pick Disease, Type C	1.1%
1128	Candidemia	1.1%

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