MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cauda Equina Syndrome

(UMLS:C0392548)

Definition:: Compressive lesion affecting the nerve roots of the CAUDA EQUINA (e.g., compression, herniation, inflammation, rupture, or stenosis), which controls the function of the bladder and bowel. Symptoms may include neurological dysfunction of bladder or bowels, loss of sexual sensation and altered sensation or paralysis in the lower extremities.
UMLS ID:: C0392548
MeSH ID:: D000077684

Classification:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.668.829.550.350|C10.668.829.800.750.150

Synonym(s)

Cauda Equina Syndrome

CAUDA EQUINA SYNDROME

Cauda equina neuritis

Cauda equina syndrome

Cauda equina syndrome, NOS

Polyneuritis equi

cauda equina syndrome

cauda equina; syndrome

lumbosacral syndrome

10.

syndrome cauda equina

11.

syndrome; cauda equina

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Bupivacaine	FAERS: 16	OFFSIDES SIDER US FAERS
2	Cytarabine	FAERS: 16	OFFSIDES SIDER US FAERS
3	Alendronate	FAERS: 6	US FAERS
4	rofecoxib	FAERS: 5	US FAERS
5	Ropivacaine	FAERS: 4 Canada Vigilance: 1	Canada Vigilance OFFSIDES SIDER US FAERS
6	Abiraterone Acetate	FAERS: 3	US FAERS
7	Losartan	FAERS: 3	US FAERS
8	Omeprazole	FAERS: 3	US FAERS
9	Prednisone	FAERS: 3	US FAERS
10	Pregabalin	FAERS: 3	US FAERS
11	Bupivacaine	FAERS: 2	US FAERS
12	Clopidogrel	FAERS: 2	US FAERS
13	Everolimus	FAERS: 2	US FAERS
14	Methylprednisolone Acetate	FAERS: 2	US FAERS
15	Tinzaparin	FAERS: 2	US FAERS
16	tofacitinib	FAERS: 2	US FAERS
17	7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11)benzoxadiazacyclotetradecine-3-carbonitrile	FAERS: 1	US FAERS
18	Albuterol	FAERS: 1	US FAERS
19	Aspirin, Dipyridamole Drug Combination	FAERS: 1	US FAERS
20	Aspirin	FAERS: 1	US FAERS
21	Baclofen	FAERS: 1	US FAERS
22	Enalapril	FAERS: 1	US FAERS
23	Esomeprazole	FAERS: 1	US FAERS
24	Finasteride	FAERS: 1	US FAERS
25	Gatifloxacin	FAERS: 1	US FAERS
26	Iohexol	FAERS: 1	US FAERS
27	Lenalidomide	FAERS: 1	US FAERS
28	Levofloxacin	FAERS: 1	US FAERS
29	Liraglutide	FAERS: 1	US FAERS
30	Lithium Carbonate	FAERS: 1	US FAERS
31	MDV 3100	FAERS: 1	SIDER US FAERS
32	Medroxyprogesterone Acetate	FAERS: 1	US FAERS
33	Mepivacaine	FAERS: 1	US FAERS
34	Methadone	FAERS: 1	US FAERS
35	Methylene Blue	FAERS: 1	US FAERS
36	Ondansetron	FAERS: 1	US FAERS
37	PCI 32765	FAERS: 1	US FAERS
38	Rivaroxaban	FAERS: 1	US FAERS
39	Sunitinib	FAERS: 1	US FAERS
40	Venlafaxine Hydrochloride	FAERS: 1	US FAERS
41	Warfarin	FAERS: 1	US FAERS
42	anagrelide	FAERS: 1	US FAERS
43	anagrelide	FAERS: 1	US FAERS
44	ceritinib	FAERS: 1	US FAERS
45	montelukast	FAERS: 1	US FAERS
46	osimertinib	FAERS: 1	US FAERS
47	reviparin	FAERS: 1	US FAERS
48	teriflunomide	FAERS: 1	US FAERS
49	Alprostadil		OFFSIDES
50	Amikacin		OFFSIDES
51	Amiloride		OFFSIDES
52	Amlodipine		OFFSIDES
53	Anastrozole		OFFSIDES
54	Bisacodyl		OFFSIDES
55	Budesonide		OFFSIDES
56	Capecitabine		OFFSIDES
57	Cefuroxime		OFFSIDES
58	Chlorhexidine		OFFSIDES
59	Chlorthalidone		OFFSIDES
60	Ciprofloxacin		OFFSIDES
61	Deamino Arginine Vasopressin		OFFSIDES
62	Ephedrine		OFFSIDES
63	Fenoterol		OFFSIDES
64	Fondaparinux		OFFSIDES
65	Fulvestrant		OFFSIDES
66	Glipizide		OFFSIDES
67	Ifosfamide		OFFSIDES
68	Indomethacin		OFFSIDES
69	Iopamidol		SIDER
70	Lactulose		OFFSIDES
71	Lidoderm		SIDER
72	Naloxone		OFFSIDES
73	Opalmon		OFFSIDES
74	Pantoprazole		OFFSIDES
75	Propofol		OFFSIDES
76	Pyridoxine		OFFSIDES
77	Rabeprazole		OFFSIDES
78	Sufentanil		OFFSIDES
79	Sulfasalazine		SIDER
80	Tamoxifen		OFFSIDES
81	Vindesine		OFFSIDES
82	Vinorelbine		OFFSIDES
83	Xipamide		OFFSIDES
84	acemetacin		OFFSIDES
85	chlorhexidine gluconate		OFFSIDES
86	mecobalamin		OFFSIDES
87	tetrazepam		OFFSIDES
88	tizanidine		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Tarsal Tunnel Syndrome	46.4%
2	Polyradiculopathy	44.1%
3	Guillain-Barre Syndrome	42.3%
4	Neuritis	41.6%
5	Polyneuritis	41.6%
6	Radiculitis	41.6%
7	Mononeuritis	41.6%
8	Mononeuropathies	41.6%
9	Brachial Plexus Neuropathies	41.6%
10	Radiculopathy	41.6%
11	Mononeuropathy Multiplex	41.6%
12	Nerve Root Compression	41.6%
13	Complex Regional Pain Syndromes	39.8%
14	Brachial Plexus Neuritis	39.4%
15	Neuralgic Amyotrophy	39.4%
16	Carpal Tunnel Syndrome	37.4%
17	Causalgia	35.3%
18	Thoracic Outlet Syndrome	33.3%
19	Peripheral Nerve Injuries	32.3%
20	Motor Neuron Disease	32.1%
21	Isaacs syndrome	32%
22	Neuromuscular Junction Diseases	31.5%
23	Diabetic Neuropathies	31.4%
24	Diabetic Amyotrophy	31.4%
25	Diabetic Autonomic Neuropathy	31.4%
26	Neuralgia	31.2%
27	Neuropathic pain	31.2%
28	Cubital Tunnel Syndrome	30%
29	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	28.4%
30	Acrodynia	27.1%
31	Sciatica	26.8%
32	Hand-Arm Vibration Syndrome	26.6%
33	Sciatic Neuropathy	26.2%
34	Ulnar Neuropathies	26.2%
35	Lesion of Sciatic Nerve	26.2%
36	Ulnar Neuritis	26.2%
37	Radial nerve compression	26.2%
38	Radial Tunnel Syndrome	26.2%
39	Peroneal Neuropathies	26.2%
40	Radial Neuropathy	26.2%
41	Median Neuropathy	26.2%
42	Sciatic Nerve Palsy	26.2%
43	Femoral Neuropathy	26.2%
44	Tibial Neuropathy	26.2%
45	Ulnar Nerve Palsy	26.2%
46	Radial nerve palsy	26.2%
47	Myopathy	24.9%
48	Stiff-Person Syndrome	24.4%
49	Reflex Sympathetic Dystrophy	24.3%
50	Miller Fisher Syndrome	23.6%
51	Polyneuropathy	22.7%
52	Cranial nerve diseases	20.2%
53	Demyelinating Diseases	20.2%
54	Demyelination	20.2%
55	Chronobiology Disorders	20.2%
56	POEMS Syndrome	19.8%
57	Chronic Fatigue Syndrome	19.7%
58	Poliomyelitis	19.3%
59	Polyradiculoneuropathy	18.4%
60	Polyradiculoneuritis	18.4%
61	Spinal Muscular Atrophy	18%
62	Progressive Muscular Atrophy	18%
63	Progressive bulbar palsy	18%
64	Bulbar palsy	18%
65	Myasthenia Gravis	17.3%
66	Cauda Equina Syndrome	16.8%
67	Neuritis, Autoimmune, Experimental	16.2%
68	Charcot-Marie-Tooth Disease	15.9%
69	Trauma, Nervous System	15.8%
70	Amyotrophic Lateral Sclerosis	15.5%
71	Nervous System Neoplasms	15.3%
72	Neurologic Manifestations	15.3%
73	Neurotoxicity Syndromes	15.3%
74	Botulism	14.3%
75	Myositis	13.7%
76	Myotonic Disorders	13.7%
77	Myasthenic Syndromes, Congenital	13.7%
78	neurofibroma	13.5%
79	Ocular Motility Disorders	13.3%
80	Cyclophoria	13.3%
81	Multiple System Atrophy	13.2%
82	Lambert-Eaton Myasthenic Syndrome	13%
83	Restless Legs Syndrome	12.7%
84	Sleep Wake Disorders	12.5%
85	Encephalomyelitis	12.4%
86	Prion Diseases	12.4%
87	Autonomic Dysreflexia	12.4%
88	Subacute Combined Degeneration	11.6%
89	Fibromyalgia	11.1%
90	Medial Tibial Stress Syndrome	11.1%
91	Mitochondrial Myopathies	11%
92	Eosinophilia-Myalgia Syndrome	10.9%
93	Amyloid Neuropathies, Familial	10.8%
94	Marchiafava-Bignami Disease	10.7%
95	Brain Diseases	10.5%
96	Dysautonomia	10.5%
97	Meningitis	10.5%
98	Movement Disorders	10.5%
99	Pachymeningitis	10.5%
100	Spinal Cord Diseases	10.5%
101	Vagus Nerve Disorder	10.5%
102	Glossopharyngeal Neuralgia	10.5%
103	Abducens Nerve Diseases	10.5%
104	Heavy Metal Poisoning, Nervous System	10.5%
105	Tauopathies	10.5%
106	Trochlear Nerve Diseases	10.5%
107	Spinal Cord Injuries	10.4%
108	Ophthalmoplegic Migraine	10.2%
109	Alstrom Syndrome	10.2%
110	Parkinson Disease	10.1%
111	Asterixis	10%
112	Ballismus	10%
113	Meningoencephalitis	9.8%
114	Refsum Disease	9.2%
115	Dandy-Walker Syndrome	9%
116	Familial Periodic Paralysis	9%
117	Pneumocephalus	9%
118	Myelitis	9%
119	Lewy Body Disease	8.9%
120	Myasthenia Gravis, Autoimmune, Experimental	8.7%
121	Myotonia Congenita	8.7%
122	Sleep Disorders, Circadian Rhythm	8.6%
123	Neuroleptic Malignant Syndrome	8.6%
124	Myelinolysis, Central Pontine	8.6%
125	Myotonic Dystrophy	8.5%
126	Polymyositis	8.5%
127	Central Nervous System Infection	8.3%
128	Optic Neuropathy	8.3%
129	Central Nervous System Cysts	8.3%
130	Striatonigral Degeneration	8.1%
131	Facial Nerve Diseases	8%
132	Craniocerebral Trauma	8%
133	Parasomnia	8%
134	Dyssomnias	8%
135	Vestibulocochlear Nerve Diseases	7.9%
136	Decerebrate State	7.9%
137	Hemiparesis	7.9%
138	Hydranencephaly	7.9%
139	Meningism	7.9%
140	Neural Tube Defects	7.9%
141	Paresis	7.9%
142	Seizures	7.9%
143	Sensation Disorders	7.9%
144	Tethered Cord Syndrome	7.9%
145	Central Nervous System Neoplasms	7.9%
146	Complex partial seizures	7.9%
147	Iniencephaly	7.9%
148	Craniorachischisis	7.9%
149	Exencephaly	7.9%
150	Monoparesis	7.9%
151	Septo-Optic Dysplasia	7.9%
152	Cortical Dysplasia	7.9%
153	Neurogenic Inflammation	7.9%
154	Gait Disorders, Neurologic	7.9%
155	Neuromuscular Manifestations	7.9%
156	Malformations of Cortical Development	7.9%
157	Epidural Abscess	7.9%
158	Olfactory Nerve Injuries	7.9%
159	Sweating, Gustatory	7.8%
160	Auriculotemporal Syndrome	7.8%
161	Progressive supranuclear palsy	7.8%
162	Myalgia	7.7%
163	Dyskinesia, Drug-Induced	7.7%
164	Myelitis, Transverse	7.7%
165	MPTP Poisoning	7.6%
166	Neurofibrosarcoma	7.5%
167	Opsoclonus-Myoclonus Syndrome	7.3%
168	Encephalomyelitis, Acute Disseminated	7.3%
169	Subdural Effusion	7.3%
170	Parkinsonian Disorders	7.3%
171	Nocturnal Myoclonus Syndrome	7.3%
172	Leukoencephalitis, Acute Hemorrhagic	7.3%
173	Brain Injuries	7.2%
174	Brain Neoplasms	7.2%
175	Multiple Sclerosis	7.2%
176	Spinal Cord Neoplasms	7.2%
177	Akathisia, Drug-Induced	7.1%
178	Horner Syndrome	7.1%
179	Neuromyelitis Optica	7%
180	Shy-Drager Syndrome	6.9%
181	Muscular Dystrophy	6.9%
182	Orbital Myositis	6.9%
183	Pyomyositis	6.8%
184	Dystonia Musculorum Deformans	6.8%
185	Facial Nerve Injuries	6.8%
186	Pupil Disorders	6.6%
187	Neurobehavioral Manifestations	6.6%
188	Mitochondrial Encephalomyopathies	6.5%
189	Paraneoplastic Encephalomyelitis	6.4%
190	Uveomeningoencephalitic Syndrome	6.3%
191	Sturge-Weber Syndrome	6.3%
192	Vertigo	6.3%
193	Alcohol-Induced Disorders, Nervous System	6.3%
194	Vasculitis, Central Nervous System	6.1%
195	Jet Lag Syndrome	6.1%
196	Brain Abscess	6.1%
197	Ophthalmoplegia	6.1%
198	External Ophthalmoplegia	6.1%
199	Leukoencephalopathy, Progressive Multifocal	6%
200	Akinetic Mutism	5.9%
201	Anoxic Encephalopathy	5.9%
202	Arachnoiditis	5.9%
203	Basal Ganglia Diseases	5.9%
204	Brain Damage, Chronic	5.9%
205	Cerebellar Diseases	5.9%
206	Encephalitis	5.9%
207	Encephalomalacia	5.9%
208	Epilepsy	5.9%
209	Hydrocephalus	5.9%
210	Congenital Hydrocephalus	5.9%
211	Hypothalamic Diseases	5.9%
212	Aseptic Meningitis	5.9%
213	Syringomyelia	5.9%
214	Thalamic Diseases	5.9%
215	Intracranial Hypertension	5.9%
216	Aura	5.9%
217	Leukoencephalopathy	5.9%
218	Essential Tremor	5.9%
219	Neuroaxonal Dystrophies	5.9%
220	Familial Tremor	5.9%
221	Headache Disorders	5.9%
222	Intracranial Hypotension	5.9%
223	Brain Edema	5.9%
224	Brain Hypoxia	5.9%
225	Aqueductal Stenosis	5.9%
226	Pneumorrhachis	5.9%
227	Writer's Cramp	5.9%
228	Scrapie	5.9%
229	Central Cord Syndrome	5.9%
230	Presenile dementia	5.9%
231	Senile dementia	5.9%
232	Meningitis, Bacterial	5.9%
233	Meningitis, Fungal	5.9%
234	Chorea	5.8%
235	Limbic Encephalitis	5.8%
236	Tuberous Sclerosis	5.7%
237	Epilepsy, Post-Traumatic	5.6%
238	Hypokalemic periodic paralysis	5.6%
239	Meige Syndrome	5.6%
240	Cerebral Ventriculitis	5.6%
241	Huntington Disease	5.4%
242	Voice Disorders	5.4%
243	Voice Disturbance	5.4%
244	Smith-Magenis syndrome	5.3%
245	Vocal Cord Paralysis	5.3%
246	Dural Arteriovenous Fistula	5.2%
247	Ataxia Telangiectasia	5%
248	Canavan Disease	5%
249	Alexander Disease	5%
250	Lupus Vasculitis, Central Nervous System	5%
251	Amblyopia	4.9%
252	Paraneoplastic Cerebellar Degeneration	4.9%
253	Brain Death	4.9%
254	Coma, Post-Head Injury	4.9%
255	Cerebrospinal Fluid Otorrhea	4.9%
256	Cerebrospinal Fluid Rhinorrhea	4.9%
257	Welander Distal Myopathy	4.8%
258	Gait Ataxia	4.8%
259	Lafora Disease	4.8%
260	Unverricht-Lundborg Syndrome	4.8%
261	Posterior Leukoencephalopathy Syndrome	4.8%
262	Posterior reversible encephalopathy syndrome	4.8%
263	Brain Diseases, Metabolic	4.6%
264	Cerebrovascular Disorders	4.6%
265	Optic Atrophy	4.6%
266	Optic Neuritis	4.6%
267	Papilledema	4.6%
268	Strabismus	4.6%
269	Tolosa-Hunt Syndrome	4.6%
270	Cerebrovascular Insufficiency	4.6%
271	Arsenic Poisoning	4.6%
272	Dementia	4.6%
273	Central Nervous System Fungal Infections	4.6%
274	Conus Medullaris Syndrome	4.6%
275	Spinal Cord Vascular Diseases	4.6%
276	Creutzfeldt-Jakob disease	4.5%
277	Basal Ganglia Cerebrovascular Disease	4.5%
278	Cerebellar Neoplasms	4.5%
279	Brain Injuries, Diffuse	4.5%
280	Traumatic Brain Injury	4.5%
281	Facial Injuries	4.5%
282	Facial Neuralgia	4.5%
283	Sleep Talking	4.5%
284	Manganese Poisoning	4.5%
285	Sleep Disorders, Intrinsic	4.5%
286	Orthostatic intolerance	4.5%
287	Cerebellar Ataxia	4.5%
288	Supratentorial Neoplasms	4.5%
289	Torticollis	4.5%
290	Multiple Sclerosis, Chronic Progressive	4.5%
291	Multiple Sclerosis, Relapsing-Remitting	4.5%
292	Alcohol Withdrawal Seizures	4.5%
293	Dementia, Vascular	4.5%
294	Anosmia	4.5%
295	Ataxia	4.5%
296	Athetosis	4.5%
297	Catalepsy	4.5%
298	Dystonia	4.5%
299	Hemiplegia	4.5%
300	Locked-In Syndrome	4.5%
301	Meningeal Neoplasms	4.5%
302	Meningomyelocele	4.5%
303	Muscle Hypertonia	4.5%
304	Muscle hypotonia	4.5%
305	Myoclonus	4.5%
306	Myotonia	4.5%
307	Paraplegia	4.5%
308	Pseudobulbar Palsy	4.5%
309	Quadriplegia	4.5%
310	Spasm	4.5%
311	Spastic Paraplegia	4.5%
312	Status Epilepticus	4.5%
313	Taste Disorders	4.5%
314	Tremor	4.5%
315	Spina Bifida	4.5%
316	Monoplegia	4.5%
317	Hypokinesia	4.5%
318	Paraparesis	4.5%
319	Bradykinesia	4.5%
320	Waxy flexibility	4.5%
321	Action Tremor	4.5%
322	Resting Tremor	4.5%
323	Dysosmia	4.5%
324	Quadriparesis	4.5%
325	Mercury Poisoning, Nervous System	4.5%
326	Olfaction Disorders	4.5%
327	Myokymia	4.5%
328	Lead Poisoning, Nervous System	4.5%
329	Vestibular Neuronitis	4.5%
330	Somatosensory Disorders	4.5%
331	Hyperkinesia	4.5%
332	Intention tremor	4.5%
333	Brain Hemorrhage, Traumatic	4.5%
334	Reflex, Abnormal	4.4%
335	Hyporeflexia	4.4%
336	Hyperreflexia	4.4%
337	Friedreich Ataxia	4.4%
338	Hepatolenticular Degeneration	4.3%
339	Carotid Artery Injuries	4.2%
340	Akathisia	4.2%
341	Restlessness	4.2%
342	Psychomotor Agitation	4.2%
343	Dermatomyositis	4.1%
344	Muscular Dystrophy, Duchenne	4.1%
345	Myoclonic Epilepsy	4%
346	Epilepsy, Temporal Lobe	4%
347	Epilepsy, Rolandic	4%
348	Benign Rolandic Epilepsy	4%
349	Tuberculosis, Meningeal	3.9%
350	Vascular Headaches	3.9%
351	Hypoxia-Ischemia, Brain	3.8%
352	Tardive Dyskinesia	3.8%
353	Persistent Vegetative State	3.8%
354	Leukomalacia, Periventricular	3.8%
355	Cerebral Palsy	3.7%
356	Epilepsies, Partial	3.7%
357	Epilepsy, Generalized	3.7%
358	Pseudotumor Cerebri	3.7%
359	Hypertensive Encephalopathy	3.7%
360	Simple Partial Seizures	3.7%
361	Epilepsy, Reflex	3.7%
362	Postural Orthostatic Tachycardia Syndrome	3.7%
363	Headache Disorders, Primary	3.7%
364	Headache Disorders, Secondary	3.7%
365	Medication overuse headache	3.7%
366	Vision Disorders	3.7%
367	Metamorphopsia	3.7%
368	Visual Impairment	3.7%
369	Optic Neuropathy, Ischemic	3.7%
370	Vertebral Artery Dissection	3.7%
371	Anterior Ischemic Optic Neuropathy	3.7%
372	Central Nervous System Bacterial Infections	3.7%
373	Amnesia, Transient Global	3.7%
374	Gait Apraxia	3.7%
375	Facial Hemiatrophy	3.7%
376	Melkersson-Rosenthal Syndrome	3.7%
377	MELAS Syndrome	3.6%
378	Anisocoria	3.6%
379	Confusion	3.6%
380	Facial paralysis	3.6%
381	Lethargy	3.6%
382	Memory Disorders	3.6%
383	Muscle Cramp	3.6%
384	Perceptual Disorders	3.6%
385	Psychomotor Disorders	3.6%
386	Tonic Pupil	3.6%
387	Anhedonia	3.6%
388	Disorientation	3.6%
389	Facial Paresis	3.6%
390	Memory Loss	3.6%
391	Hemisensory Neglect	3.6%
392	Dysacusis	3.6%
393	Alice in Wonderland Syndrome	3.6%
394	Sleep Bruxism	3.6%
395	Anencephaly	3.6%
396	Meningocele	3.6%
397	Muscular Atrophy	3.6%
398	Respiratory Paralysis	3.6%
399	Encephalocele	3.6%
400	Tetany	3.6%
401	Optic Nerve Glioma	3.5%
402	Brain Concussion	3.4%
403	Toxoplasmosis, Cerebral	3.4%
404	Kearns-Sayre syndrome	3.3%
405	Acoustic Neuroma	3.2%
406	Meningitis, Cryptococcal	3.2%
407	Meningitis, Listeria	3.2%
408	Meningitis, Haemophilus	3.2%
409	Meningitis, Pneumococcal	3.2%
410	Frontotemporal dementia	3.2%
411	Diffuse Axonal Injury	3.2%
412	Brain Stem Neoplasms	3.2%
413	Juvenile Myoclonic Epilepsy	3.2%
414	Myoclonic Epilepsies, Progressive	3.2%
415	Duane Retraction Syndrome	3.1%
416	Consciousness Disorders	3.1%
417	Mental Retardation	3.1%
418	Muscle Weakness	3.1%
419	Depressed Level of Consciousness	3.1%
420	Mental deficiency	3.1%
421	Intellectual Disability	3.1%
422	Mobius Syndrome	3%
423	Bell Palsy	3%
424	Catatonia	3%
425	Herpes Zoster Oticus	3%
426	Aphonia	3%
427	Sleep Deprivation	3%
428	Dysphonia	3%
429	Pituitary Diseases	3%
430	Pituitary Adenoma	2.9%
431	Pituitary Neoplasms	2.9%
432	Giant Cell Arteritis	2.9%
433	Temporal Arteritis	2.9%
434	Auditory Perceptual Disorders	2.8%
435	Carotid Artery Diseases	2.8%
436	Brain Ischemia	2.8%
437	Esotropia	2.8%
438	Exotropia	2.8%
439	Hypotension, Orthostatic	2.8%
440	Sleep Apnea Syndromes	2.8%
441	Cerebrovascular accident	2.8%
442	Kluver-Bucy Syndrome	2.8%
443	Vasospasm, Intracranial	2.8%
444	Spinal Cord Ischemia	2.8%
445	Intracranial Arterial Diseases	2.8%
446	Post-Exercise Hypotension	2.8%
447	Disorders of Excessive Somnolence	2.8%
448	Sleep Initiation and Maintenance Disorders	2.8%
449	Night Terrors	2.8%
450	Somnambulism	2.8%
451	Trigeminal Nerve Disorder	2.8%
452	Transient Insomnia	2.8%
453	Sleep Paralysis	2.8%
454	Chronic Insomnia	2.8%
455	REM Sleep Behavior Disorder	2.8%
456	Hypersomnia	2.8%
457	Dermal Sinus	2.8%
458	Dysgeusia	2.8%
459	Formication	2.8%
460	Hyperalgesia	2.8%
461	Hyperesthesia	2.8%
462	Hypesthesia	2.8%
463	Language Disorders	2.8%
464	Numbness	2.8%
465	Paresthesia	2.8%
466	Paraparesis, Spastic	2.8%
467	Spina Bifida Cystica	2.8%
468	Trismus	2.8%
469	Spina Bifida Occulta	2.8%
470	Epilepsia Partialis Continua	2.8%
471	Hypogeusia	2.8%
472	Meningeal Carcinomatosis	2.8%
473	Brown-Sequard Syndrome	2.8%
474	Lissencephaly	2.8%
475	Polymicrogyria	2.8%
476	Pachygyria	2.8%
477	Schizencephaly	2.8%
478	Lockjaw	2.8%
479	Allodynia	2.8%
480	Lead Poisoning, Nervous System, Childhood	2.8%
481	Lead Poisoning, Nervous System, Adult	2.8%
482	Periventricular Nodular Heterotopia	2.8%
483	Ageusia	2.8%
484	Tuberculosis, Central Nervous System	2.8%
485	Basal Ganglia Hemorrhage	2.8%
486	Classical Lissencephalies and Subcortical Band Heterotopias	2.7%
487	Pituitary Apoplexy	2.7%
488	Adrenoleukodystrophy	2.7%
489	Brain Contusion	2.7%
490	Brain Infarction	2.7%
491	Post-Traumatic Headache	2.7%
492	Tension Headache	2.7%
493	Epilepsy, Complex Partial	2.7%
494	Migraine Disorders	2.7%
495	Abdominal Migraine	2.7%
496	Status Migrainosus	2.7%
497	Cervicogenic Headache	2.7%
498	Subarachnoid Hemorrhage, Traumatic	2.7%
499	Carotid Artery, Internal, Dissection	2.7%
500	Subacute Sclerosing Panencephalitis	2.5%
501	Neuronal Ceroid-Lipofuscinoses	2.5%
502	Choroid Plexus Papilloma	2.5%
503	Eye Injuries	2.4%
504	Congenital nystagmus	2.3%
505	Aicardi's syndrome	2.3%
506	Diplopia	2.3%
507	Muscle Rigidity	2.3%
508	Muscle Spasticity	2.3%
509	Scotoma	2.3%
510	Photophobia	2.3%
511	Cogwheel Rigidity	2.3%
512	Hemifacial Spasm	2.3%
513	Amaurosis	2.3%
514	Blindness	2.3%
515	Nuchal Rigidity	2.3%
516	Alexia	2.3%
517	Dyslexia	2.3%
518	Reye Syndrome	2.3%
519	Neuroaspergillosis	2.3%
520	Hoarseness	2.3%
521	Putaminal Hemorrhage	2.3%
522	Intracranial Embolism and Thrombosis	2.3%
523	Hepatic Encephalopathy	2.3%
524	Cockayne Syndrome	2.3%
525	Agnosia	2.3%
526	Apraxias	2.3%
527	Hallucinations	2.3%
528	Hemianopsia	2.3%
529	Hyperacusis	2.3%
530	Tinnitus	2.3%
531	Visual Agnosia	2.3%
532	Anosognosia	2.3%
533	Wernicke-Korsakoff Syndrome	2.3%
534	Phonophobia	2.3%
535	Hearing Loss	2.3%
536	Alcohol Withdrawal Delirium	2.2%
537	Sarcopenia	2.2%
538	Hematoma, Subdural	2.2%
539	Hematoma, Epidural, Cranial	2.2%
540	Infarction, Middle Cerebral Artery	2.2%
541	Infarction, Anterior Cerebral Artery	2.2%
542	Infarction, Posterior Cerebral Artery	2.2%
543	Optic Atrophy, Hereditary, Leber	2.2%
544	Cluster Headache	2.1%
545	Migraine with Aura	2.1%
546	Familial Hemiplegic Migraine	2.1%
547	Chronic Paroxysmal Hemicrania	2.1%
548	SUNCT Syndrome	2.1%
549	Paroxysmal Hemicrania	2.1%
550	Cerebral Infarction	2.1%
551	Brain Stem Infarctions	2.1%
552	Moyamoya Disease	2.1%
553	Empty Sella Syndrome	2%
554	Hyperpituitarism	2%
555	Hypopituitarism	2%
556	Hypophysitis	2%
557	Holoprosencephaly	2%
558	Cerebral Arterial Diseases	2%
559	Vertebrobasilar Insufficiency	2%
560	Anterior Spinal Artery Syndrome	2%
561	Basilar Artery Stenosis	2%
562	Vertebral Artery Stenosis	2%
563	Sleep Apnea, Obstructive	2%
564	Sleep Apnea, Central	2%
565	Intracranial Hemorrhage, Hypertensive	2%
566	Transient Cerebral Ischemia	2%
567	Pseudorabies	2%
568	Narcolepsy	2%
569	Trigeminal Neuralgia	2%
570	Kleine-Levin Syndrome	2%
571	Agraphia	2%
572	Anomia	2%
573	Cluttering	2%
574	Language Development Disorders	2%
575	Speech Disorders	2%
576	Syncope	2%
577	Stupor	2%
578	Dysgraphia	2%
579	Presyncope	2%
580	Dyslalia	2%
581	Amnesia	1.9%
582	Delirium	1.9%
583	Dissociative Amnesia	1.9%
584	Color blindness	1.9%
585	Global Amnesia	1.9%
586	Cri-du-Chat Syndrome	1.9%
587	Down Syndrome	1.9%
588	Brain Diseases, Metabolic, Inborn	1.9%
589	Trisomy 21	1.9%
590	Meningioma	1.9%
591	Williams Syndrome	1.9%
592	Microcephaly	1.9%
593	Macrocephaly	1.9%
594	Neurosyphilis	1.9%
595	Porencephaly	1.9%
596	West Nile Fever	1.9%
597	Lateral Medullary Syndrome	1.8%
598	Hematoma, Subdural, Intracranial	1.7%
599	Hematoma, Subdural, Chronic	1.7%
600	Hematoma, Subdural, Acute	1.7%
601	Toxoplasmosis, Congenital	1.6%
602	Prader-Willi Syndrome	1.6%
603	Eye Burns	1.6%
604	Wernicke Encephalopathy	1.6%
605	Malaria, Cerebral	1.6%
606	AIDS Dementia Complex	1.6%
607	Carotid Stenosis	1.6%
608	Intracranial Aneurysm	1.6%
609	Hyperprolactinemia	1.6%
610	Phantom pain	1.6%
611	Phantom Limb Pain	1.6%
612	Neurocysticercosis	1.6%
613	Lyme Neuroborreliosis	1.6%
614	Amaurosis Fugax	1.6%
615	Blindness, Cortical	1.6%
616	Dyscalculia	1.6%
617	Intracranial Arteriosclerosis	1.6%
618	Cerebral Atherosclerosis	1.6%
619	Rett Syndrome	1.6%
620	Subarachnoid Hemorrhage	1.6%
621	Cerebral Arteriosclerosis	1.6%
622	Cerebral Hemorrhage	1.6%
623	Cerebral Thrombosis	1.6%
624	Intracranial Embolism	1.6%
625	Intracranial Thrombosis	1.6%
626	Deafness	1.6%
627	Hearing Loss, Sudden	1.6%
628	Gerstmann Syndrome	1.6%
629	Hearing Loss, Bilateral	1.6%
630	Hearing Loss, High-Frequency	1.6%
631	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
632	Prosopagnosia	1.6%
633	Apraxia, Ideomotor	1.6%
634	Charles Bonnet Syndrome	1.6%
635	Hearing Loss, Unilateral	1.6%
636	Complete Hearing Loss	1.6%
637	Alien Hand Syndrome	1.6%
638	Deaf Mutism	1.6%
639	Subclavian Steal Syndrome	1.6%
640	Pick Disease of the Brain	1.6%
641	Cataplexy	1.6%
642	Aphasia	1.6%
643	Articulation Disorders	1.6%
644	Echolalia	1.6%
645	Stuttering	1.6%
646	Dysphasia	1.6%
647	Kernicterus	1.4%
648	Dysarthria	1.4%
649	Corneal Scar	1.4%
650	Menkes Kinky Hair Syndrome	1.3%
651	Retrograde amnesia	1.3%
652	Amnesia, Anterograde	1.3%
653	Carotid Artery Thrombosis	1.3%
654	Waterhouse-Friderichsen Syndrome	1.3%
655	Mutism	1.3%
656	Selective Mutism	1.3%
657	Acromegaly	1.3%
658	Cerebral Amyloid Angiopathy	1.3%
659	Rubinstein-Taybi Syndrome	1.3%
660	Sinus Thrombosis, Intracranial	1.3%
661	Fragile X Syndrome	1.1%
662	Alexia, Pure	1.1%
663	Cavernous Sinus Thrombosis	1.1%
664	Sagittal Sinus Thrombosis	1.1%
665	Corneal Perforation	1.1%
666	Galactosemias	1%
667	Urea Cycle Disorders, Inborn	1%
668	Tyrosinemias	1%
669	Fabry Disease	1%
670	Nelson Syndrome	0.9%
671	Prolactinoma	0.9%
672	Growth Hormone-Secreting Pituitary Adenoma	0.9%
673	Homocystinuria	0.9%
674	Leigh Disease	0.9%
675	Mucopolysaccharidosis II	0.8%
676	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.7%
677	Zellweger Syndrome	0.7%
678	Glycogen storage disease type II	0.6%
679	Gaucher Disease	0.5%
680	Tay-Sachs Disease	0.4%
681	Niemann-Pick Disease, Type C	0.4%

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