MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lymphoma, Extranodal NK-T-Cell

(UMLS:C1955906)

Definition:: An extranodal neoplasm, usually possessing an NK-cell phenotype and associated with EPSTEIN-BARR VIRUS. These lymphomas exhibit a broad morphologic spectrum, frequent necrosis, angioinvasion, and most commonly present in the midfacial region, but also in other extranodal sites.
UMLS ID:: C1955906
MeSH ID:: D054391

Classification:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.386.480.750.199

Synonym(s)

Lymphoma, Extranodal NK-T-Cell

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Cyclophosphamide	20839428	CTD
2	Doxorubicin	20839428	CTD
3	Prednisone	20839428	CTD
4	Vincristine	20839428	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Lymphoma, T-Cell, Cutaneous	24.5%
2	Enteropathy-Associated T-Cell Lymphoma	24.5%
3	leukemia	22.7%
4	Neoplasms, Germ Cell and Embryonal	22.7%
5	Neoplasms, Glandular and Epithelial	22.7%
6	Germ Cell Cancer	22.7%
7	Mycosis Fungoides	18.3%
8	Lymphomatoid Papulosis	18.3%
9	Lymphoma, Follicular	17.9%
10	Mantle cell lymphoma	17.9%
11	Neuroectodermal Tumors	16.4%
12	Composite Lymphoma	16.3%
13	Hamartoma	15.3%
14	Neoplasms, Hormone-Dependent	15.3%
15	Neoplasms, Multiple Primary	15.3%
16	Paraneoplastic Syndromes	15.3%
17	Precancerous Conditions	15.3%
18	Neoplasms, Second Primary	15.3%
19	Histiocytic Disorders, Malignant	15.1%
20	Hodgkin Disease	14.2%
21	Neoplasms, Neuroepithelial	13.4%
22	Gliomatosis cerebri	13.4%
23	Carcinosarcoma	13%
24	Hemangiosarcoma	13%
25	lymphangiosarcoma	13%
26	Lymphomatoid Granulomatosis	12.6%
27	Sezary Syndrome	12.4%
28	Adenoma	12.2%
29	Ameloblastoma	12.2%
30	Angiokeratoma	12.2%
31	Carcinoma	12.2%
32	Chordoma	12.2%
33	Hemangioma	12.2%
34	hemangiopericytoma	12.2%
35	Lymphangioma	12.2%
36	Mesenchymoma	12.2%
37	Nevus	12.2%
38	Teratoma	12.2%
39	Hepatoblastoma	12.2%
40	Mixed Tumor, Mullerian	12.2%
41	Germinoma	12.2%
42	Teratocarcinoma	12.2%
43	Angiofibroma	12.2%
44	Sarcoma	12.2%
45	Epithelioma	12.2%
46	Lymphoma, AIDS-Related	11.9%
47	Primary Effusion Lymphoma	11.9%
48	melanoma	10.8%
49	Meningioma	10.4%
50	Cyst	10.2%
51	Neoplastic Processes	10.2%
52	Neoplastic Syndromes, Hereditary	10.2%
53	Pregnancy Complications, Neoplastic	10.2%
54	Trophoblastic Neoplasms	10%
55	Leukemia, Experimental	10%
56	Carcinoma, Ehrlich Tumor	9.9%
57	Dermoid Cyst	9.9%
58	Carcinoma, Lewis Lung	9.9%
59	Neoplasms, Experimental	9.9%
60	Carcinoma 256, Walker	9.8%
61	Leukemia, Plasma Cell	9.7%
62	Basal cell carcinoma	9.6%
63	Carcinoma, Papillary	9.6%
64	Squamous cell carcinoma	9.6%
65	Chondrosarcoma	9.6%
66	Craniopharyngioma	9.6%
67	Cystadenoma	9.6%
68	leiomyosarcoma	9.6%
69	liposarcoma	9.6%
70	Mesothelioma	9.6%
71	synovial sarcoma	9.6%
72	Neuroectodermal Tumor, Melanotic	9.6%
73	Angiomyolipoma	9.6%
74	Clear Cell Sarcoma of Soft Tissue	9.6%
75	Alveolar Soft Part Sarcoma	9.6%
76	Neuroendocrine Tumors	9.6%
77	Sarcoma, Myeloid	9.6%
78	Carcinoma, Basal Cell	9.6%
79	Plasmablastic lymphoma	8.9%
80	Adenoma, Acidophil	8.4%
81	Ganglioneuroma	8.4%
82	Glioma	8.4%
83	Malignant Glioma	8.4%
84	Plasmacytoma	8.2%
85	Malignant histiocytosis	8.1%
86	Histiocytic sarcoma	8.1%
87	Leukemia, Radiation-Induced	8.1%
88	Burkitt Lymphoma	8%
89	Cystadenocarcinoma	8%
90	Fibrosarcoma	8%
91	Osteosarcoma	8%
92	Mucoepidermoid Carcinoma	8%
93	Leukemia L1210	7.6%
94	Leukemia P388	7.6%
95	Acanthoma	7.6%
96	Abdominal Neoplasms	7.6%
97	Erythroplasia	7.6%
98	Follicular cyst	7.6%
99	Head and Neck Neoplasms	7.6%
100	Mucocele	7.6%
101	Pilonidal Cyst	7.6%
102	Soft Tissue Neoplasms	7.6%
103	Thoracic Neoplasms	7.6%
104	Thyroglossal Cyst	7.6%
105	Synovial Cyst	7.6%
106	Aberrant Crypt Foci	7.6%
107	Neoplasms, Radiation-Induced	7.4%
108	Sarcoma, Experimental	7.4%
109	Thymoma	7.3%
110	Melanoma, Experimental	7.3%
111	Adenocarcinoma	7.2%
112	Carcinoma in Situ	7.2%
113	Carcinoma, Transitional Cell	7.2%
114	Phyllodes Tumor	7.2%
115	Dysgerminoma	7.2%
116	Hemangioendothelioma	7.2%
117	Lipoma	7.2%
118	Myoma	7.2%
119	Myxoma	7.2%
120	Neuroma	7.2%
121	Papilloma	7.2%
122	Pseudomyxoma Peritonei	7.2%
123	Seminoma	7.2%
124	Papillomatosis	7.2%
125	Angiolipoma	7.2%
126	Myelolipoma	7.2%
127	Neoplasms, Bone Tissue	7.2%
128	Neoplasms, Fibrous Tissue	7.2%
129	Smooth Muscle Tumor	7.2%
130	Adenomatosis, Pulmonary	7.2%
131	Adenomatous Polyps	7.2%
132	Carcinoma, Large Cell	7.2%
133	Carcinoma, Small Cell	7.2%
134	Desmoplastic Small Round Cell Tumor	7.2%
135	Chondroma	7.2%
136	Enchondroma	7.2%
137	Adenofibroma	7.2%
138	Fibroadenoma	7.2%
139	Malignant Fibrous Histiocytoma	7.2%
140	Carcinoid Tumor	7.1%
141	Neurilemmoma	7.1%
142	Hutchinson's Melanotic Freckle	7.1%
143	Melanoma, Amelanotic	7.1%
144	Medulloblastoma	6.8%
145	Endometrial Stromal Sarcoma	6.7%
146	Multiple Endocrine Neoplasia	6.6%
147	Choriocarcinoma	6.5%
148	Carcinoma, Lobular	6.5%
149	Bowen's Disease	6.3%
150	Paraganglioma	6.3%
151	Rhabdomyosarcoma	6.3%
152	Giant Cell Tumor of Bone	6.3%
153	Paraneoplastic Encephalomyelitis	6%
154	Astrocytoma	5.9%
155	Ependymoma	5.9%
156	oligodendroglioma	5.9%
157	Ganglioglioma	5.9%
158	gliosarcoma	5.9%
159	Anaplastic astrocytoma	5.9%
160	Anaplastic Oligodendroglioma	5.9%
161	Sarcoma 180	5.9%
162	Mammary Neoplasms, Experimental	5.8%
163	Lymphangioleiomyomatosis	5.8%
164	Dermatofibrosarcoma	5.5%
165	Dermatofibrosarcoma Protuberans	5.5%
166	Digestive System Neoplasms	5.4%
167	Endocrine Gland Neoplasms	5.4%
168	Eye Neoplasms	5.4%
169	Nervous System Neoplasms	5.4%
170	Malignant Carcinoid Syndrome	5.3%
171	Bone neoplasms	5.1%
172	Leukoplakia	5.1%
173	Lymphocele	5.1%
174	Pancreatic Cyst	5.1%
175	Skin Neoplasms	5.1%
176	Hematologic Neoplasms	5.1%
177	Barrett Esophagus	5%
178	Breast Cyst	5%
179	Actinic keratosis	5%
180	Mediastinal Cyst	5%
181	Neoplasm Invasiveness	5%
182	Neoplasm Metastasis	5%
183	Neoplasm Recurrence, Local	5%
184	Parovarian Cyst	5%
185	Pericardial Cyst	5%
186	Splenic Neoplasms	5%
187	Thymic Cyst	5%
188	Carcinogenesis	5%
189	Myxoid cyst	5%
190	Metastasis	5%
191	Primary amyloidosis	4.9%
192	Retinoblastoma	4.9%
193	Leukemia, Myelomonocytic, Chronic	4.8%
194	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.8%
195	Adenoid Cystic Carcinoma	4.8%
196	fibroma	4.8%
197	Fibromatosis	4.8%
198	Osteoblastoma	4.8%
199	Osteoma	4.8%
200	Rhabdomyoma	4.8%
201	Chondromatosis	4.8%
202	Adenocarcinoma, Clear Cell	4.8%
203	Cholangiocarcinoma	4.8%
204	Cervical Intraepithelial Neoplasia	4.8%
205	Hemangioblastoma	4.8%
206	Pheochromocytoma	4.7%
207	Alveolar rhabdomyosarcoma	4.7%
208	Glioblastoma	4.7%
209	Neuroblastoma	4.7%
210	Glioblastoma Multiforme	4.7%
211	Nephroblastoma	4.7%
212	Tuberous Sclerosis	4.6%
213	Neurofibrosarcoma	4.4%
214	Ganglioneuroblastoma	4.1%
215	Retroperitoneal Neoplasms	4.1%
216	Hepatocellular Adenoma	3.9%
217	Mesoblastic Nephroma	3.9%
218	Basal Cell Nevus Syndrome	3.8%
219	Mastocytosis	3.7%
220	Sturge-Weber Syndrome	3.7%
221	Corpus Luteum Cyst	3.7%
222	Ovarian Cysts	3.7%
223	Gastrointestinal Stromal Tumors	3.7%
224	Hemangioma, Cavernous	3.6%
225	Carcinoid Heart Disease	3.6%
226	Leukemia, T-Cell	3.6%
227	Leukemia, B-Cell	3.6%
228	neurofibroma	3.6%
229	Hydatidiform Mole	3.6%
230	Fibromatosis, Aggressive	3.6%
231	Fibromatosis, Abdominal	3.6%
232	Klatskin Tumor	3.6%
233	Multiple Endocrine Neoplasia Type 1	3.5%
234	Waldenstrom Macroglobulinemia	3.5%
235	Multiple Myeloma	3.5%
236	Parathyroid Neoplasms	3.4%
237	Peritoneal Neoplasms	3.4%
238	Thyroid Neoplasm	3.4%
239	Thyroid carcinoma	3.4%
240	Carcinoma, Pancreatic Ductal	3.3%
241	Liver Neoplasms, Experimental	3.3%
242	Prolactinoma	3.2%
243	Growth Hormone-Secreting Pituitary Adenoma	3.2%
244	Mastocytoma	3.2%
245	Mastocytosis, Systemic	3.2%
246	Leukemia, Myeloid, Chronic-Phase	3.2%
247	Choledochal Cyst	3.1%
248	Acoustic Neuroma	3%
249	Peutz-Jeghers Syndrome	3%
250	Pancreatic Neoplasm	2.8%
251	Mouth Neoplasms	2.8%
252	Central Nervous System Neoplasms	2.8%
253	Vascular Neoplasms	2.8%
254	Thymus Neoplasms	2.8%
255	granulosa cell tumor	2.8%
256	Carcinoma, Ovarian Epithelial	2.8%
257	Genital Neoplasms, Female	2.7%
258	Pancreatic Pseudocyst	2.7%
259	Lymphatic Metastasis	2.7%
260	Neoplasms, Unknown Primary	2.7%
261	Leukemic Infiltration	2.7%
262	Breast Neoplasms, Male	2.7%
263	Neoplasm Micrometastasis	2.7%
264	Triple Negative Breast Neoplasms	2.7%
265	Tracheal Neoplasms	2.7%
266	Optic Nerve Glioma	2.7%
267	Adenomatous Polyposis Coli	2.7%
268	Leukoplakia, Oral	2.6%
269	Paraneoplastic Cerebellar Degeneration	2.6%
270	Vipoma	2.6%
271	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
272	Leukemia, Large Granular Lymphocytic	2.4%
273	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.4%
274	insulinoma	2.3%
275	Esophageal Neoplasms	2.2%
276	Limbic Encephalitis	2.2%
277	Adrenocortical carcinoma	2.1%
278	Adrenal Gland Neoplasms	2.1%
279	Gastrointestinal Neoplasms	2.1%
280	Genital Neoplasms, Male	2.1%
281	Liver neoplasms	2.1%
282	Uveal Neoplasms	2.1%
283	Nasopharyngeal carcinoma	2.1%
284	Urologic Neoplasms	2.1%
285	Sebaceous Gland Neoplasms	2.1%
286	Spinal Neoplasms	2.1%
287	Bone Marrow Neoplasms	2.1%
288	Polycystic Ovary Syndrome	2%
289	Thyroid Nodule	2%
290	Gastrinoma	1.9%
291	Glucagonoma	1.9%
292	Denys-Drash Syndrome	1.9%
293	Lambert-Eaton Myasthenic Syndrome	1.9%
294	Testicular Neoplasms	1.9%
295	Leydig Cell Tumor	1.9%
296	Dupuytren Contracture	1.9%
297	Renal Cell Carcinoma	1.8%
298	Papillary Renal Cell Carcinoma	1.8%
299	Urticaria Pigmentosa	1.8%
300	Carcinoma, Endometrioid	1.7%
301	Xeroderma Pigmentosum	1.7%
302	Opsoclonus-Myoclonus Syndrome	1.7%
303	Meningeal Neoplasms	1.6%
304	Myelitis, Transverse	1.5%
305	ovarian neoplasm	1.4%
306	Nose Neoplasms	1.3%
307	Ear Neoplasms	1.3%
308	Eyelid Neoplasms	1.3%
309	Lung Neoplasms	1.3%
310	Pleural Neoplasms	1.3%
311	Cell Transformation, Viral	1.2%
312	Brain Neoplasms	1.2%
313	Salivary Gland Neoplasms	1.2%
314	Spinal Cord Neoplasms	1.2%
315	Tongue Neoplasms	1.2%
316	Uterine Neoplasms	1.2%
317	Vaginal Neoplasms	1.2%
318	Vulvar Neoplasms	1.2%
319	Uterine Cancer	1.2%
320	Fallopian Tube Neoplasms	1.2%
321	Palatal Neoplasms	1.2%
322	Pituitary Adenoma	1.1%
323	Pituitary Neoplasms	1.1%
324	Meningeal Carcinomatosis	1.1%
325	Zollinger-Ellison syndrome	1%
326	Pharyngeal Neoplasms	1%
327	Central Nervous System Cysts	1%
328	Bile Duct Neoplasms	1%
329	gallbladder neoplasm	1%
330	Intestinal Neoplasms	1%
331	Penile Neoplasms	1%
332	Prostatic Neoplasms	1%
333	Stomach Neoplasms	1%
334	Polycythemia Vera	1%
335	Laryngeal neoplasm	0.9%
336	Bronchial Neoplasms	0.8%
337	Bladder Neoplasm	0.8%
338	Kidney Neoplasm	0.8%
339	Ureteral Neoplasms	0.8%
340	Urethral Neoplasms	0.8%
341	Multiple Pulmonary Nodules	0.8%
342	Supratentorial Neoplasms	0.8%
343	Endometrial Neoplasms	0.8%
344	Hypopharyngeal Neoplasms	0.7%
345	Pleural Effusion, Malignant	0.7%
346	Hypopharyngeal Cancer	0.7%
347	Parotid Neoplasms	0.6%
348	Prostatic Neoplasms, Castration-Resistant	0.6%
349	Nelson Syndrome	0.6%
350	Brain Stem Neoplasms	0.6%
351	Cecal Neoplasms	0.5%
352	Duodenal Neoplasms	0.5%
353	Choroid Plexus Papilloma	0.5%
354	Tonsillar Neoplasms	0.5%
355	Cerebellar Neoplasms	0.5%
356	Nasopharyngeal Neoplasms	0.5%
357	Colorectal Neoplasms	0.5%
358	Paranasal Sinus Neoplasms	0.4%
359	Radicular Cyst	0.4%
360	Appendiceal Neoplasms	0.4%
361	Colonic Neoplasms	0.4%
362	Rectal Neoplasms	0.4%
363	Maxillary Sinus Neoplasms	0.3%
364	Anus Neoplasms	0.3%
365	Sigmoid Neoplasms	0.3%

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