MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lyme Neuroborreliosis

(UMLS:C0752235)

Definition:: Nervous system infections caused by tick-borne spirochetes of the BORRELIA BURGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153(2):182-91)
UMLS ID:: C0752235
MeSH ID:: D020852

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.200.450|C01.252.400.155.569.600|C01.252.400.825.480.700|C01.252.847.193.569.600

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.228.180.437

Synonym(s)

Lyme Neuroborreliosis

Bannwarth syndrome

Bannworth's syndrome

Garin-Bujadoux-Bannwarth syndrome

Infection of central nervous system caused by Borrelia burgdorferi

Lyme disease infection of CNS caused by Borrelia burgdorferi

Lyme neuroborreliosis

Neurological Lyme disease

Tick-borne meningopolyneuritis

10.

bannwarth syndrome

11.

bannworth's syndrome

12.

lyme disease bannwarth syndrome

13.

neurological disorders in Lyme disease

14.

neurological lyme disease

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ceftriaxone		19225737	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Relapsing Fever	53.7%
2	Erythema Chronicum Migrans	49.3%
3	Leptospirosis	45.9%
4	Neurosyphilis	44.9%
5	Human Ehrlichiosis	37.2%
6	Meningitis, Bacterial	36.3%
7	Human anaplasmosis	33.5%
8	Japanese Spotted Fever	32.6%
9	Gram-Positive Bacterial Infections	31.9%
10	Tuberculosis, Meningeal	31.2%
11	Meningitis, Haemophilus	31.2%
12	Syphilis	30.8%
13	Meningitis, Listeria	30.5%
14	Borrelia Infections	29.7%
15	Bordetella Infections	29.4%
16	Brucellosis	29.4%
17	Campylobacter infection	29.4%
18	Enterobacteriaceae Infections	29.4%
19	Pseudomonas Infections	29.4%
20	Q Fever	29.4%
21	Vibrio Infections	29.4%
22	Helicobacter Infections	29.4%
23	Neisseriaceae Infections	29.4%
24	Burkholderia Infections	29.4%
25	Flavobacteriaceae Infections	29.4%
26	Moraxellaceae Infections	29.4%
27	Burkholderia cepacia Infection	29.4%
28	Skin Diseases, Bacterial	28.7%
29	Bacteremia	28.6%
30	Meningitis, Pneumococcal	28.3%
31	Bacterial Vaginosis	27.2%
32	Lyme Disease	26.6%
33	Bacterial Endocarditis	25.8%
34	Central Nervous System Bacterial Infections	24.8%
35	Chlamydia Infections	24.7%
36	Gonorrhea	24.7%
37	Pneumonia, Bacterial	24%
38	Rocky Mountain Spotted Fever	23.8%
39	Erysipelas	23.2%
40	Staphylococcal Skin Infections	23.2%
41	Lyme Neuroborreliosis	22.8%
42	Impetigo	21.5%
43	Erythrasma	21%
44	Ecthyma	20.9%
45	Subacute Bacterial Endocarditis	20.9%
46	Mycetoma	20.9%
47	Brain Abscess	20.8%
48	Tuberculosis, Central Nervous System	19.9%
49	Mycoses	19.8%
50	Infection	19.8%
51	Central Nervous System Fungal Infections	19%
52	Pertussis	18.8%
53	Actinomycetales Infections	18.6%
54	Clostridium Infections	18.6%
55	Listeriosis	18.6%
56	Staphylococcal Infections	18.6%
57	Streptococcal Infections	18.6%
58	Bacillaceae Infections	18.6%
59	Clostridium difficile infection	18.6%
60	Epidural Abscess	18.6%
61	Acinetobacter Infections	18.5%
62	Bacteroides Infections	18.5%
63	Cholera	18.5%
64	Escherichia coli Infections	18.5%
65	Haemophilus Infections	18.5%
66	Klebsiella Infections	18.5%
67	Meningococcal Infections	18.5%
68	Mycoplasma Infections	18.5%
69	Pasteurella Infections	18.5%
70	Proteus Infections	18.5%
71	Rickettsia Infections	18.5%
72	Salmonella infections	18.5%
73	Scrub Typhus	18.5%
74	Serratia Infections	18.5%
75	Ureaplasma Infections	18.5%
76	Rhinoscleroma	18.3%
77	Syphilis, Congenital	18.3%
78	Meningoencephalitis	18%
79	Ulcerative stomatitis	17.8%
80	Hidradenitis Suppurativa	17.3%
81	Gram-Negative Bacterial Infections	17.2%
82	Central Nervous System Infection	17.1%
83	Encephalomyelitis	16.9%
84	Lymphogranuloma Venereum	16.8%
85	Erysipelothrix infection	16.5%
86	Waterhouse-Friderichsen Syndrome	15.9%
87	Staphylococcal Scalded Skin Syndrome	15.8%
88	Ophthalmia Neonatorum	15.5%
89	Trachoma	15.5%
90	Hordeolum	15.3%
91	Bacterial conjunctivitis	15.2%
92	Neuroaspergillosis	15%
93	Furunculosis	14.4%
94	furuncle	14.4%
95	Meningitis, Fungal	14%
96	Myelitis	13.9%
97	Dysentery, Bacillary	13.9%
98	Psittacosis	13.1%
99	Paratyphoid Fever	13.1%
100	Plague	13.1%
101	Typhoid Fever	13.1%
102	TYPHUS	13.1%
103	Yersinia pseudotuberculosis Infections	13.1%
104	Bubonic Plague	13.1%
105	Toxoplasmosis, Cerebral	12.8%
106	Dermatomycoses	12.7%
107	Meningitis, Cryptococcal	12.7%
108	carbuncle	12.2%
109	Prion Diseases	12.2%
110	Actinomycosis	12.1%
111	Corynebacterium Infections	12.1%
112	Gas Gangrene	12.1%
113	Mycobacterium Infections	12.1%
114	Nocardia Infections	12.1%
115	Pneumococcal Infections	12.1%
116	Scarlet Fever	12.1%
117	Tetanus	12.1%
118	Pulmonary Nocardiosis	12.1%
119	Salmonella Infections, Animal	11.6%
120	Salmonella food poisoning	11.3%
121	Botulism	11.1%
122	Candidiasis, Chronic Mucocutaneous	11%
123	Cutaneous Candidiasis	11%
124	Panophthalmitis	11%
125	Erythema Induratum	10.8%
126	Aspergillosis	10.6%
127	Candidiasis	10.6%
128	Coccidioidomycosis	10.6%
129	Histoplasmosis	10.6%
130	Paracoccidioidomycosis	10.6%
131	Pelvic Infection	10.6%
132	Wound Infection	10.6%
133	Zygomycosis	10.6%
134	Soft Tissue Infection	10.6%
135	Community-Acquired Infections	10.6%
136	Phaeohyphomycosis	10.6%
137	Pneumocystis Infections	10.6%
138	Subdural Effusion	10.6%
139	Joint Tuberculosis	10.1%
140	Tuberculosis, Osteoarticular	10.1%
141	Bone Tuberculosis	10.1%
142	Candidemia	9.6%
143	Eye Infection	9.4%
144	Respiratory Tract Infections	9.4%
145	Fungemia	9.3%
146	Bone Diseases, Infectious	9.2%
147	Otomycosis	9.2%
148	Pregnancy Complications, Infectious	9.2%
149	Skin Diseases, Infectious	9.2%
150	Rheumatic Fever	9.2%
151	Cerebral Ventriculitis	9.2%
152	Arthritis, Infectious	9.1%
153	Piedra	9.1%
154	Suppuration	9.1%
155	Cross Infection	9.1%
156	Septicemia	9.1%
157	Sepsis	9.1%
158	Enterocolitis, Pseudomembranous	9.1%
159	pseudomembranous colitis	9.1%
160	Poliomyelitis	9%
161	Blastomycosis	9%
162	Diphtheria	8.8%
163	Leprosy	8.8%
164	Mycobacterium Infections, Nontuberculous	8.8%
165	Tuberculosis	8.8%
166	Mycobacterium abscessus Infection	8.8%
167	Lupus Vasculitis, Central Nervous System	8.6%
168	Ocular Motility Disorders	8.5%
169	Cyclophoria	8.5%
170	Opportunistic Infections	8.4%
171	Leukoencephalopathy, Progressive Multifocal	8.4%
172	Cellulitis	8.4%
173	Multiple System Atrophy	8.4%
174	Pneumocephalus	8.3%
175	Brain Diseases	8.2%
176	Meningitis	8.2%
177	Movement Disorders	8.2%
178	Pachymeningitis	8.2%
179	Spinal Cord Diseases	8.2%
180	Lung Diseases, Fungal	8.1%
181	Creutzfeldt-Jakob disease	8.1%
182	Urinary tract infection	8.1%
183	Chromoblastomycosis	7.7%
184	Dermatophytosis	7.7%
185	Sporotrichosis	7.7%
186	Tinea	7.7%
187	Tinea Versicolor	7.7%
188	Trichophytosis	7.7%
189	Invasive Pulmonary Aspergillosis	7.7%
190	Hyalohyphomycosis	7.7%
191	Rheumatic Heart Disease	7.7%
192	Endotoxemia	7.7%
193	Limbic Encephalitis	7.5%
194	Sexually Transmitted Diseases	7.3%
195	Myelitis, Transverse	7.3%
196	Lemierre Syndrome	7.3%
197	Mycobacterium avium-intracellulare Infection	7.2%
198	Lymph Node Tuberculosis	7.2%
199	Tuberculosis, Miliary	7.2%
200	Tuberculosis, Multidrug-Resistant	7.2%
201	Leprosy, Multibacillary	7.2%
202	Latent Tuberculosis	7.2%
203	Lewy Body Disease	7%
204	Stiff-Person Syndrome	7%
205	Tuberculosis, Spinal	7%
206	Scrapie	7%
207	Parkinsonian Disorders	6.9%
208	Subacute Sclerosing Panencephalitis	6.7%
209	Borderline leprosy	6.4%
210	Leprosy, Lepromatous	6.4%
211	Tuberculoid leprosy	6.4%
212	Extensively Drug-Resistant Tuberculosis	6.4%
213	Parkinson Disease	6.3%
214	Tuberculosis, Gastrointestinal	6.3%
215	Subacute Combined Degeneration	6.3%
216	Mucormycosis	6.2%
217	Dandy-Walker Syndrome	6.2%
218	Spinal Muscular Atrophy	6.1%
219	Progressive Muscular Atrophy	6.1%
220	Progressive supranuclear palsy	5.9%
221	Spinal Cord Injuries	5.9%
222	Amyotrophic Lateral Sclerosis	5.9%
223	Dementia, Vascular	5.8%
224	Asterixis	5.7%
225	Ballismus	5.7%
226	Striatonigral Degeneration	5.6%
227	Tuberculosis, Pulmonary	5.5%
228	Meige Syndrome	5.5%
229	Pyomyositis	5.5%
230	Dystonia Musculorum Deformans	5.4%
231	Oral candidiasis	5.4%
232	Endophthalmitis	5.4%
233	Peritonitis	5.4%
234	Osteomyelitis	5.3%
235	Periostitis	5.3%
236	Surgical Wound Infection	5.3%
237	Pulmonary Aspergillosis	5.3%
238	Bronchopulmonary Aspergillosis	5.3%
239	Abscess	5.3%
240	Adnexitis	5.3%
241	Empyema	5.3%
242	Pelvic Inflammatory Disease	5.3%
243	Huntington Disease	5.3%
244	Chronic Fatigue Syndrome	5.3%
245	Pseudorabies	5.2%
246	Fusariosis	5.2%
247	West Nile Fever	5.2%
248	Marchiafava-Bignami Disease	5.1%
249	Shy-Drager Syndrome	5%
250	Cranial nerve diseases	5%
251	Demyelinating Diseases	5%
252	Demyelination	5%
253	Neuromuscular Diseases	5%
254	Chronobiology Disorders	5%
255	Epilepsy, Post-Traumatic	5%
256	Brain Injuries	4.9%
257	Brain Neoplasms	4.9%
258	Spinal Cord Neoplasms	4.9%
259	Akinetic Mutism	4.9%
260	Anoxic Encephalopathy	4.9%
261	Arachnoiditis	4.9%
262	Basal Ganglia Diseases	4.9%
263	Brain Damage, Chronic	4.9%
264	Cerebellar Diseases	4.9%
265	Encephalitis	4.9%
266	Encephalomalacia	4.9%
267	Epilepsy	4.9%
268	Hydrocephalus	4.9%
269	Congenital Hydrocephalus	4.9%
270	Hypothalamic Diseases	4.9%
271	Aseptic Meningitis	4.9%
272	Syringomyelia	4.9%
273	Thalamic Diseases	4.9%
274	Intracranial Hypertension	4.9%
275	Aura	4.9%
276	Leukoencephalopathy	4.9%
277	Essential Tremor	4.9%
278	Neuroaxonal Dystrophies	4.9%
279	Familial Tremor	4.9%
280	Headache Disorders	4.9%
281	Intracranial Hypotension	4.9%
282	Brain Edema	4.9%
283	Brain Hypoxia	4.9%
284	Aqueductal Stenosis	4.9%
285	Pneumorrhachis	4.9%
286	Writer's Cramp	4.9%
287	Basal Ganglia Cerebrovascular Disease	4.8%
288	Ophthalmoplegic Migraine	4.8%
289	Posterior Leukoencephalopathy Syndrome	4.8%
290	Posterior reversible encephalopathy syndrome	4.8%
291	MPTP Poisoning	4.8%
292	Superinfection	4.8%
293	Motor Neuron Disease	4.7%
294	Corneal Ulcer	4.7%
295	Puerperal Infection	4.7%
296	Spondylitis	4.7%
297	Appendicitis	4.7%
298	Bacteriuria	4.7%
299	Pyuria	4.7%
300	Tinea Capitis	4.7%
301	Onychomycosis	4.7%
302	Opsoclonus-Myoclonus Syndrome	4.7%
303	Restless Legs Syndrome	4.6%
304	Endotoxic shock	4.6%
305	Septic Shock	4.6%
306	Toxic Shock Syndrome	4.6%
307	Akathisia, Drug-Induced	4.6%
308	Candidiasis, Vulvovaginal	4.6%
309	Hepatolenticular Degeneration	4.6%
310	Leukoencephalitis, Acute Hemorrhagic	4.5%
311	Neuroleptic Malignant Syndrome	4.5%
312	Myelinolysis, Central Pontine	4.5%
313	Trauma, Nervous System	4.4%
314	Polyradiculoneuropathy	4.4%
315	Polyradiculoneuritis	4.4%
316	Nervous System Neoplasms	4.3%
317	Neurologic Manifestations	4.3%
318	Neurotoxicity Syndromes	4.3%
319	Leukomalacia, Periventricular	4.3%
320	Toxoplasmosis, Congenital	4.3%
321	Cerebellar Neoplasms	4.3%
322	Malaria, Cerebral	4.3%
323	Vascular Headaches	4.2%
324	Neurocysticercosis	4.2%
325	Hypoxia-Ischemia, Brain	4.2%
326	Brain Diseases, Metabolic	4.2%
327	Cerebrovascular Disorders	4.2%
328	Cerebrovascular Insufficiency	4.2%
329	Dementia	4.2%
330	Conus Medullaris Syndrome	4.2%
331	Spinal Cord Vascular Diseases	4.2%
332	Dyskinesia, Drug-Induced	4.2%
333	Tinea Pedis	4.2%
334	Brain Death	4.1%
335	Myoclonic Epilepsy	4.1%
336	Epilepsy, Temporal Lobe	4.1%
337	Epilepsy, Rolandic	4.1%
338	Benign Rolandic Epilepsy	4.1%
339	Arthritis, Reactive	4.1%
340	Miller Fisher Syndrome	4.1%
341	Friedreich Ataxia	4%
342	Psoas Abscess	4%
343	Abdominal Abscess	4%
344	Amblyopia	4%
345	Tuberculosis, Renal	3.9%
346	Sleep Wake Disorders	3.9%
347	AIDS-Related Opportunistic Infections	3.8%
348	Encephalomyelitis, Acute Disseminated	3.8%
349	Autonomic Dysreflexia	3.7%
350	Complex Regional Pain Syndromes	3.7%
351	Basal Ganglia Hemorrhage	3.7%
352	Central Cord Syndrome	3.7%
353	Brain Hemorrhage, Traumatic	3.7%
354	Presenile dementia	3.7%
355	Senile dementia	3.7%
356	Chorea	3.6%
357	Vasculitis, Central Nervous System	3.6%
358	Canavan Disease	3.5%
359	Alexander Disease	3.5%
360	Carotid Artery Injuries	3.5%
361	Pituitary Adenoma	3.5%
362	Pituitary Neoplasms	3.5%
363	Lafora Disease	3.5%
364	Unverricht-Lundborg Syndrome	3.5%
365	Diverticulitis	3.4%
366	Juvenile Myoclonic Epilepsy	3.4%
367	Myoclonic Epilepsies, Progressive	3.4%
368	Guillain-Barre Syndrome	3.4%
369	Amnesia, Transient Global	3.4%
370	Peripheral Nerve Injuries	3.3%
371	Lambert-Eaton Myasthenic Syndrome	3.3%
372	Myasthenia Gravis	3.3%
373	Pituitary Apoplexy	3.2%
374	Paraneoplastic Cerebellar Degeneration	3.2%
375	Brain Injuries, Diffuse	3.2%
376	Traumatic Brain Injury	3.2%
377	Cerebral Palsy	3.2%
378	Epilepsies, Partial	3.2%
379	Epilepsy, Generalized	3.2%
380	Pseudotumor Cerebri	3.2%
381	Hypertensive Encephalopathy	3.2%
382	Simple Partial Seizures	3.2%
383	Epilepsy, Reflex	3.2%
384	Headache Disorders, Primary	3.2%
385	Headache Disorders, Secondary	3.2%
386	Medication overuse headache	3.2%
387	Cerebellar Ataxia	3.2%
388	Supratentorial Neoplasms	3.2%
389	Torticollis	3.2%
390	Brain Infarction	3.2%
391	Putaminal Hemorrhage	3.1%
392	Lung Abscess	3.1%
393	Diverticulum	3.1%
394	Diverticulosis	3.1%
395	Infarction, Middle Cerebral Artery	3%
396	Infarction, Anterior Cerebral Artery	3%
397	Infarction, Posterior Cerebral Artery	3%
398	Discitis	3%
399	Mastoiditis	3%
400	Petrositis	3%
401	Persistent Vegetative State	3%
402	Neuromyelitis Optica	3%
403	Sleep Disorders, Circadian Rhythm	3%
404	Central Nervous System Cysts	2.9%
405	Olfactory Nerve Injuries	2.9%
406	Pituitary Diseases	2.9%
407	Causalgia	2.8%
408	Progressive bulbar palsy	2.8%
409	Bulbar palsy	2.8%
410	Carotid Artery Diseases	2.8%
411	Brain Ischemia	2.8%
412	Cerebrovascular accident	2.8%
413	Kluver-Bucy Syndrome	2.8%
414	Vasospasm, Intracranial	2.8%
415	Spinal Cord Ischemia	2.8%
416	Intracranial Arterial Diseases	2.8%
417	Ataxia Telangiectasia	2.8%
418	Dysautonomia	2.7%
419	Vagus Nerve Disorder	2.7%
420	Glossopharyngeal Neuralgia	2.7%
421	Abducens Nerve Diseases	2.7%
422	Heavy Metal Poisoning, Nervous System	2.7%
423	Neuromuscular Junction Diseases	2.7%
424	Tauopathies	2.7%
425	Trochlear Nerve Diseases	2.7%
426	Peripheral Nervous System Diseases	2.7%
427	Retropharyngeal Abscess	2.7%
428	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.7%
429	Peritonsillar Abscess	2.7%
430	Cerebral Infarction	2.7%
431	Brain Stem Infarctions	2.7%
432	Moyamoya Disease	2.7%
433	Adrenoleukodystrophy	2.6%
434	Tardive Dyskinesia	2.6%
435	Facial Nerve Injuries	2.6%
436	Mitochondrial Encephalomyopathies	2.6%
437	Liver Abscess	2.6%
438	Horner Syndrome	2.5%
439	Subarachnoid Hemorrhage, Traumatic	2.5%
440	Carotid Artery, Internal, Dissection	2.5%
441	Aspergillosis, Allergic Bronchopulmonary	2.4%
442	Multiple Sclerosis	2.4%
443	Reye Syndrome	2.4%
444	Vertebral Artery Dissection	2.4%
445	Intracranial Embolism and Thrombosis	2.4%
446	Hepatic Encephalopathy	2.4%
447	Myopathy	2.4%
448	Optic Neuropathy	2.4%
449	Post-Traumatic Headache	2.4%
450	Tension Headache	2.4%
451	Epilepsy, Complex Partial	2.4%
452	Migraine Disorders	2.4%
453	Abdominal Migraine	2.4%
454	Status Migrainosus	2.4%
455	Cervicogenic Headache	2.4%
456	MELAS Syndrome	2.4%
457	Diffuse Axonal Injury	2.4%
458	Brain Stem Neoplasms	2.4%
459	Lateral Medullary Syndrome	2.4%
460	Tuberous Sclerosis	2.4%
461	Facial Nerve Diseases	2.4%
462	Craniocerebral Trauma	2.4%
463	Parasomnia	2.4%
464	Dyssomnias	2.4%
465	Myasthenia Gravis, Autoimmune, Experimental	2.4%
466	Auditory Perceptual Disorders	2.4%
467	Vestibulocochlear Nerve Diseases	2.3%
468	Decerebrate State	2.3%
469	Hemiparesis	2.3%
470	Hydranencephaly	2.3%
471	Meningism	2.3%
472	Neural Tube Defects	2.3%
473	Paresis	2.3%
474	Seizures	2.3%
475	Sensation Disorders	2.3%
476	Tethered Cord Syndrome	2.3%
477	Central Nervous System Neoplasms	2.3%
478	Complex partial seizures	2.3%
479	Iniencephaly	2.3%
480	Craniorachischisis	2.3%
481	Exencephaly	2.3%
482	Monoparesis	2.3%
483	Septo-Optic Dysplasia	2.3%
484	Cortical Dysplasia	2.3%
485	Neurogenic Inflammation	2.3%
486	Gait Disorders, Neurologic	2.3%
487	Neuromuscular Manifestations	2.3%
488	Malformations of Cortical Development	2.3%
489	Brain Concussion	2.3%
490	Sweating, Gustatory	2.3%
491	Auriculotemporal Syndrome	2.3%
492	Frontotemporal dementia	2.3%
493	Reflex Sympathetic Dystrophy	2.3%
494	Nocturnal Myoclonus Syndrome	2.3%
495	Jet Lag Syndrome	2.3%
496	Alice in Wonderland Syndrome	2.3%
497	Refsum Disease	2.2%
498	Ophthalmoplegia	2.2%
499	External Ophthalmoplegia	2.2%
500	Brain Diseases, Metabolic, Inborn	2.2%
501	Brain Contusion	2.1%
502	Pupil Disorders	2.1%
503	Neurobehavioral Manifestations	2.1%
504	Charcot-Marie-Tooth Disease	2.1%
505	Empty Sella Syndrome	2.1%
506	Hyperpituitarism	2.1%
507	Hypopituitarism	2.1%
508	Hypophysitis	2.1%
509	Paraneoplastic Encephalomyelitis	2.1%
510	Cerebral Arterial Diseases	2.1%
511	Vertebrobasilar Insufficiency	2.1%
512	Anterior Spinal Artery Syndrome	2.1%
513	Basilar Artery Stenosis	2.1%
514	Vertebral Artery Stenosis	2.1%
515	Intracranial Hemorrhage, Hypertensive	2.1%
516	Transient Cerebral Ischemia	2.1%
517	Uveomeningoencephalitic Syndrome	2.1%
518	Sturge-Weber Syndrome	2%
519	Vertigo	2%
520	Alcohol-Induced Disorders, Nervous System	2%
521	Giant Cell Arteritis	2%
522	Temporal Arteritis	2%
523	Acrodynia	2%
524	Cluster Headache	2%
525	Migraine with Aura	2%
526	Familial Hemiplegic Migraine	2%
527	Chronic Paroxysmal Hemicrania	2%
528	SUNCT Syndrome	2%
529	Paroxysmal Hemicrania	2%
530	Choroid Plexus Papilloma	2%
531	Vocal Cord Paralysis	2%
532	Wernicke Encephalopathy	1.9%
533	AIDS Dementia Complex	1.9%
534	Voice Disorders	1.9%
535	Voice Disturbance	1.9%
536	Brachial Plexus Neuritis	1.8%
537	Neuralgic Amyotrophy	1.8%
538	Smith-Magenis syndrome	1.8%
539	Dural Arteriovenous Fistula	1.8%
540	Carotid Stenosis	1.8%
541	Intracranial Aneurysm	1.8%
542	Myotonia Congenita	1.8%
543	Intracranial Arteriosclerosis	1.8%
544	Cerebral Atherosclerosis	1.8%
545	Subarachnoid Hemorrhage	1.8%
546	Cerebral Arteriosclerosis	1.8%
547	Cerebral Hemorrhage	1.8%
548	Cerebral Thrombosis	1.8%
549	Intracranial Embolism	1.8%
550	Intracranial Thrombosis	1.8%
551	Cerebrospinal Fluid Otorrhea	1.8%
552	Cerebrospinal Fluid Rhinorrhea	1.8%
553	Neuritis, Autoimmune, Experimental	1.8%
554	Kernicterus	1.8%
555	Gait Ataxia	1.8%
556	Alcohol Withdrawal Seizures	1.8%
557	Myotonic Dystrophy	1.8%
558	Hyperprolactinemia	1.7%
559	Coma, Post-Head Injury	1.7%
560	Subclavian Steal Syndrome	1.7%
561	Pick Disease of the Brain	1.7%
562	Hematoma, Subdural	1.7%
563	Hematoma, Epidural, Cranial	1.7%
564	Reflex, Abnormal	1.6%
565	Hyporeflexia	1.6%
566	Hyperreflexia	1.6%
567	Akathisia	1.6%
568	Restlessness	1.6%
569	Psychomotor Agitation	1.6%
570	Neuritis	1.6%
571	Polyneuritis	1.6%
572	Radiculitis	1.6%
573	Polyneuropathy	1.6%
574	Mononeuritis	1.6%
575	Mononeuropathies	1.6%
576	Brachial Plexus Neuropathies	1.6%
577	Radiculopathy	1.6%
578	Mononeuropathy Multiplex	1.6%
579	Nerve Root Compression	1.6%
580	Multiple Sclerosis, Chronic Progressive	1.6%
581	Multiple Sclerosis, Relapsing-Remitting	1.6%
582	Tarsal Tunnel Syndrome	1.6%
583	Cauda Equina Syndrome	1.6%
584	Carotid Artery Thrombosis	1.6%
585	Optic Nerve Glioma	1.6%
586	Acromegaly	1.5%
587	Alstrom Syndrome	1.5%
588	Cerebral Amyloid Angiopathy	1.5%
589	Sinus Thrombosis, Intracranial	1.5%
590	Fabry Disease	1.5%
591	Liver Abscess, Amebic	1.5%
592	Gait Apraxia	1.4%
593	Hematoma, Subdural, Intracranial	1.4%
594	Hematoma, Subdural, Chronic	1.4%
595	Hematoma, Subdural, Acute	1.4%
596	Carpal Tunnel Syndrome	1.4%
597	neurofibroma	1.4%
598	Myositis	1.4%
599	Optic Atrophy	1.4%
600	Optic Neuritis	1.4%
601	Papilledema	1.4%
602	Strabismus	1.4%
603	Tolosa-Hunt Syndrome	1.4%
604	Isaacs syndrome	1.4%
605	Arsenic Poisoning	1.4%
606	Myotonic Disorders	1.4%
607	Myasthenic Syndromes, Congenital	1.4%
608	Sciatica	1.4%
609	Diabetic Neuropathies	1.4%
610	Facial Injuries	1.4%
611	Facial Neuralgia	1.4%
612	Diabetic Amyotrophy	1.4%
613	Diabetic Autonomic Neuropathy	1.4%
614	Sleep Talking	1.4%
615	Manganese Poisoning	1.4%
616	Sleep Disorders, Intrinsic	1.4%
617	Orthostatic intolerance	1.4%
618	Acoustic Neuroma	1.4%
619	Anosmia	1.4%
620	Ataxia	1.4%
621	Athetosis	1.4%
622	Catalepsy	1.4%
623	Dystonia	1.4%
624	Hemiplegia	1.4%
625	Locked-In Syndrome	1.4%
626	Meningeal Neoplasms	1.4%
627	Meningomyelocele	1.4%
628	Muscle Hypertonia	1.4%
629	Muscle hypotonia	1.4%
630	Myoclonus	1.4%
631	Myotonia	1.4%
632	Neuralgia	1.4%
633	Paraplegia	1.4%
634	Pseudobulbar Palsy	1.4%
635	Quadriplegia	1.4%
636	Spasm	1.4%
637	Spastic Paraplegia	1.4%
638	Status Epilepticus	1.4%
639	Taste Disorders	1.4%
640	Tremor	1.4%
641	Spina Bifida	1.4%
642	Monoplegia	1.4%
643	Hypokinesia	1.4%
644	Paraparesis	1.4%
645	Bradykinesia	1.4%
646	Waxy flexibility	1.4%
647	Action Tremor	1.4%
648	Resting Tremor	1.4%
649	Dysosmia	1.4%
650	Quadriparesis	1.4%
651	Mercury Poisoning, Nervous System	1.4%
652	Olfaction Disorders	1.4%
653	Myokymia	1.4%
654	Lead Poisoning, Nervous System	1.4%
655	Vestibular Neuronitis	1.4%
656	Somatosensory Disorders	1.4%
657	Neuropathic pain	1.4%
658	Hyperkinesia	1.4%
659	Intention tremor	1.4%
660	Amyloid Neuropathies, Familial	1.3%
661	Cavernous Sinus Thrombosis	1.3%
662	Sagittal Sinus Thrombosis	1.3%
663	Galactosemias	1.3%
664	Urea Cycle Disorders, Inborn	1.3%
665	Tyrosinemias	1.3%
666	Menkes Kinky Hair Syndrome	1.3%
667	Hand-Arm Vibration Syndrome	1.3%
668	Vision Disorders	1.2%
669	Metamorphopsia	1.2%
670	Visual Impairment	1.2%
671	Fibromyalgia	1.2%
672	Optic Neuropathy, Ischemic	1.2%
673	Anterior Ischemic Optic Neuropathy	1.2%
674	Medial Tibial Stress Syndrome	1.2%
675	Facial Hemiatrophy	1.2%
676	Melkersson-Rosenthal Syndrome	1.2%
677	Mitochondrial Myopathies	1.2%
678	Anisocoria	1.2%
679	Confusion	1.2%
680	Facial paralysis	1.2%
681	Lethargy	1.2%
682	Memory Disorders	1.2%
683	Muscle Cramp	1.2%
684	Perceptual Disorders	1.2%
685	Psychomotor Disorders	1.2%
686	Tonic Pupil	1.2%
687	Eosinophilia-Myalgia Syndrome	1.2%
688	Anhedonia	1.2%
689	Disorientation	1.2%
690	Facial Paresis	1.2%
691	Memory Loss	1.2%
692	Hemisensory Neglect	1.2%
693	Dysacusis	1.2%
694	Sleep Bruxism	1.2%
695	Anencephaly	1.2%
696	Meningocele	1.2%
697	Muscular Atrophy	1.2%
698	Respiratory Paralysis	1.2%
699	Encephalocele	1.2%
700	Homocystinuria	1.2%
701	Prolactinoma	1.2%
702	Growth Hormone-Secreting Pituitary Adenoma	1.2%
703	Tetany	1.2%
704	Leigh Disease	1.2%
705	Cubital Tunnel Syndrome	1.2%
706	Nelson Syndrome	1.2%
707	Classical Lissencephalies and Subcortical Band Heterotopias	1.1%
708	Duane Retraction Syndrome	1.1%
709	Consciousness Disorders	1.1%
710	Mental Retardation	1.1%
711	Muscle Weakness	1.1%
712	Depressed Level of Consciousness	1.1%
713	Mental deficiency	1.1%
714	Intellectual Disability	1.1%
715	Mobius Syndrome	1.1%
716	Bell Palsy	1.1%
717	Catatonia	1.1%
718	Herpes Zoster Oticus	1.1%
719	Familial Periodic Paralysis	1.1%
720	Aphonia	1.1%
721	Sleep Deprivation	1.1%
722	Dysphonia	1.1%
723	Sciatic Neuropathy	1.1%
724	Ulnar Neuropathies	1.1%
725	Lesion of Sciatic Nerve	1.1%
726	Ulnar Neuritis	1.1%
727	Radial nerve compression	1.1%
728	Radial Tunnel Syndrome	1.1%
729	Peroneal Neuropathies	1.1%
730	Radial Neuropathy	1.1%
731	Median Neuropathy	1.1%
732	Sciatic Nerve Palsy	1.1%
733	Femoral Neuropathy	1.1%
734	Tibial Neuropathy	1.1%
735	Ulnar Nerve Palsy	1.1%
736	Postural Orthostatic Tachycardia Syndrome	1.1%
737	Radial nerve palsy	1.1%
738	Carbamoyl-Phosphate Synthase I Deficiency Disease	1%
739	Myalgia	1%
740	Zellweger Syndrome	1%
741	Neuronal Ceroid-Lipofuscinoses	1%
742	Kearns-Sayre syndrome	1%
743	Alexia	1%
744	Dyslexia	1%
745	Optic Atrophy, Hereditary, Leber	0.9%
746	Thoracic Outlet Syndrome	0.9%
747	Esotropia	0.9%
748	Exotropia	0.9%
749	Hypotension, Orthostatic	0.9%
750	Sleep Apnea Syndromes	0.9%
751	Polymyositis	0.9%
752	Post-Exercise Hypotension	0.9%
753	Glycogen storage disease type II	0.9%
754	Disorders of Excessive Somnolence	0.9%
755	Sleep Initiation and Maintenance Disorders	0.9%
756	Night Terrors	0.9%
757	Somnambulism	0.9%
758	Trigeminal Nerve Disorder	0.9%
759	Transient Insomnia	0.9%
760	Sleep Paralysis	0.9%
761	Chronic Insomnia	0.9%
762	REM Sleep Behavior Disorder	0.9%
763	Hypersomnia	0.9%
764	Dermal Sinus	0.9%
765	Dysgeusia	0.9%
766	Formication	0.9%
767	Hyperalgesia	0.9%
768	Hyperesthesia	0.9%
769	Hypesthesia	0.9%
770	Language Disorders	0.9%
771	Numbness	0.9%
772	Paresthesia	0.9%
773	Paraparesis, Spastic	0.9%
774	Spina Bifida Cystica	0.9%
775	Trismus	0.9%
776	Spina Bifida Occulta	0.9%
777	Epilepsia Partialis Continua	0.9%
778	Hypogeusia	0.9%
779	Meningeal Carcinomatosis	0.9%
780	Brown-Sequard Syndrome	0.9%
781	Lissencephaly	0.9%
782	Polymicrogyria	0.9%
783	Pachygyria	0.9%
784	Schizencephaly	0.9%
785	Lockjaw	0.9%
786	Allodynia	0.9%
787	Lead Poisoning, Nervous System, Childhood	0.9%
788	Lead Poisoning, Nervous System, Adult	0.9%
789	Periventricular Nodular Heterotopia	0.9%
790	Ageusia	0.9%
791	Aicardi's syndrome	0.9%
792	Hoarseness	0.9%
793	Cockayne Syndrome	0.9%
794	Alcohol Withdrawal Delirium	0.9%
795	Neurofibrosarcoma	0.9%
796	Eye Injuries	0.8%
797	Muscular Dystrophy	0.8%
798	Congenital nystagmus	0.8%
799	Orbital Myositis	0.8%
800	Holoprosencephaly	0.8%
801	Diplopia	0.8%
802	Muscle Rigidity	0.8%
803	Muscle Spasticity	0.8%
804	Scotoma	0.8%
805	Photophobia	0.8%
806	Cogwheel Rigidity	0.8%
807	Hemifacial Spasm	0.8%
808	Amaurosis	0.8%
809	Blindness	0.8%
810	Nuchal Rigidity	0.8%
811	Agnosia	0.8%
812	Apraxias	0.8%
813	Hallucinations	0.8%
814	Hemianopsia	0.8%
815	Hyperacusis	0.8%
816	Tinnitus	0.8%
817	Visual Agnosia	0.8%
818	Anosognosia	0.8%
819	Wernicke-Korsakoff Syndrome	0.8%
820	Phonophobia	0.8%
821	Hearing Loss	0.8%
822	Sarcopenia	0.8%
823	Polyradiculopathy	0.8%
824	Gaucher Disease	0.8%
825	Amnesia	0.7%
826	Delirium	0.7%
827	Dissociative Amnesia	0.7%
828	Color blindness	0.7%
829	Global Amnesia	0.7%
830	Cri-du-Chat Syndrome	0.7%
831	Down Syndrome	0.7%
832	Trisomy 21	0.7%
833	POEMS Syndrome	0.7%
834	Meningioma	0.7%
835	Williams Syndrome	0.7%
836	Microcephaly	0.7%
837	Macrocephaly	0.7%
838	Hypokalemic periodic paralysis	0.7%
839	Porencephaly	0.7%
840	Tay-Sachs Disease	0.7%
841	Sleep Apnea, Obstructive	0.7%
842	Sleep Apnea, Central	0.7%
843	Narcolepsy	0.7%
844	Trigeminal Neuralgia	0.7%
845	Kleine-Levin Syndrome	0.7%
846	Agraphia	0.7%
847	Anomia	0.7%
848	Cluttering	0.7%
849	Language Development Disorders	0.7%
850	Speech Disorders	0.7%
851	Syncope	0.7%
852	Stupor	0.7%
853	Dysgraphia	0.7%
854	Presyncope	0.7%
855	Dyslalia	0.7%
856	Niemann-Pick Disease, Type C	0.7%
857	Prader-Willi Syndrome	0.7%
858	Phantom pain	0.6%
859	Phantom Limb Pain	0.6%
860	Eye Burns	0.6%
861	Welander Distal Myopathy	0.6%
862	Amaurosis Fugax	0.6%
863	Blindness, Cortical	0.6%
864	Dyscalculia	0.6%
865	Rett Syndrome	0.6%
866	Deafness	0.6%
867	Hearing Loss, Sudden	0.6%
868	Gerstmann Syndrome	0.6%
869	Hearing Loss, Bilateral	0.6%
870	Hearing Loss, High-Frequency	0.6%
871	Hearing Loss, Mixed Conductive-Sensorineural	0.6%
872	Prosopagnosia	0.6%
873	Apraxia, Ideomotor	0.6%
874	Charles Bonnet Syndrome	0.6%
875	Hearing Loss, Unilateral	0.6%
876	Complete Hearing Loss	0.6%
877	Alien Hand Syndrome	0.6%
878	Deaf Mutism	0.6%
879	Cataplexy	0.6%
880	Aphasia	0.6%
881	Articulation Disorders	0.6%
882	Echolalia	0.6%
883	Stuttering	0.6%
884	Dysphasia	0.6%
885	Dermatomyositis	0.5%
886	Corneal Scar	0.5%
887	Rubinstein-Taybi Syndrome	0.5%
888	Muscular Dystrophy, Duchenne	0.5%
889	Retrograde amnesia	0.5%
890	Amnesia, Anterograde	0.5%
891	Dysarthria	0.5%
892	Mutism	0.5%
893	Selective Mutism	0.5%
894	Fragile X Syndrome	0.5%
895	Alexia, Pure	0.5%
896	Corneal Perforation	0.4%
897	Mucopolysaccharidosis II	0.4%

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